Amino acid dipepetide frequency for Sida leaf curl virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.094AlaAla: 8.094 ± 2.657
1.799AlaCys: 1.799 ± 0.725
0.0AlaAsp: 0.0 ± 0.0
0.899AlaGlu: 0.899 ± 1.002
1.799AlaPhe: 1.799 ± 1.395
0.899AlaGly: 0.899 ± 0.78
2.698AlaHis: 2.698 ± 1.431
0.899AlaIle: 0.899 ± 0.78
3.597AlaLys: 3.597 ± 1.456
6.295AlaLeu: 6.295 ± 2.07
0.0AlaMet: 0.0 ± 0.0
2.698AlaAsn: 2.698 ± 1.373
2.698AlaPro: 2.698 ± 1.16
3.597AlaGln: 3.597 ± 1.357
4.496AlaArg: 4.496 ± 1.621
5.396AlaSer: 5.396 ± 1.988
5.396AlaThr: 5.396 ± 3.156
2.698AlaVal: 2.698 ± 1.645
0.899AlaTrp: 0.899 ± 0.672
1.799AlaTyr: 1.799 ± 0.725
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.799CysCys: 1.799 ± 2.004
0.0CysAsp: 0.0 ± 0.0
1.799CysGlu: 1.799 ± 0.725
0.899CysPhe: 0.899 ± 0.966
1.799CysGly: 1.799 ± 1.043
0.899CysHis: 0.899 ± 1.031
0.0CysIle: 0.0 ± 0.0
3.597CysLys: 3.597 ± 1.86
0.899CysLeu: 0.899 ± 0.78
0.0CysMet: 0.0 ± 0.0
0.899CysAsn: 0.899 ± 0.672
1.799CysPro: 1.799 ± 2.004
0.899CysGln: 0.899 ± 0.672
1.799CysArg: 1.799 ± 0.725
2.698CysSer: 2.698 ± 1.157
2.698CysThr: 2.698 ± 2.003
0.899CysVal: 0.899 ± 0.78
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.698AspAla: 2.698 ± 1.16
0.0AspCys: 0.0 ± 0.0
1.799AspAsp: 1.799 ± 0.725
2.698AspGlu: 2.698 ± 0.859
0.899AspPhe: 0.899 ± 0.78
1.799AspGly: 1.799 ± 1.344
1.799AspHis: 1.799 ± 1.932
1.799AspIle: 1.799 ± 1.173
1.799AspLys: 1.799 ± 0.725
5.396AspLeu: 5.396 ± 2.078
1.799AspMet: 1.799 ± 1.395
1.799AspAsn: 1.799 ± 1.031
2.698AspPro: 2.698 ± 1.206
0.899AspGln: 0.899 ± 1.002
5.396AspArg: 5.396 ± 1.862
5.396AspSer: 5.396 ± 1.822
1.799AspThr: 1.799 ± 0.725
3.597AspVal: 3.597 ± 1.451
0.899AspTrp: 0.899 ± 0.672
1.799AspTyr: 1.799 ± 1.037
0.0AspXaa: 0.0 ± 0.0
Glu
1.799GluAla: 1.799 ± 0.725
0.899GluCys: 0.899 ± 1.031
0.899GluAsp: 0.899 ± 0.781
7.194GluGlu: 7.194 ± 4.493
2.698GluPhe: 2.698 ± 1.431
6.295GluGly: 6.295 ± 1.956
0.899GluHis: 0.899 ± 1.031
0.899GluIle: 0.899 ± 1.002
1.799GluLys: 1.799 ± 1.037
4.496GluLeu: 4.496 ± 1.996
0.0GluMet: 0.0 ± 0.0
5.396GluAsn: 5.396 ± 1.959
3.597GluPro: 3.597 ± 1.195
0.899GluGln: 0.899 ± 1.002
0.0GluArg: 0.0 ± 0.0
3.597GluSer: 3.597 ± 1.525
1.799GluThr: 1.799 ± 1.037
2.698GluVal: 2.698 ± 1.419
2.698GluTrp: 2.698 ± 1.419
3.597GluTyr: 3.597 ± 1.357
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.899PheCys: 0.899 ± 0.78
4.496PheAsp: 4.496 ± 1.361
1.799PheGlu: 1.799 ± 1.037
1.799PhePhe: 1.799 ± 1.037
0.0PheGly: 0.0 ± 0.0
3.597PheHis: 3.597 ± 1.064
0.899PheIle: 0.899 ± 0.966
1.799PheLys: 1.799 ± 0.979
6.295PheLeu: 6.295 ± 1.949
0.899PheMet: 0.899 ± 0.672
3.597PheAsn: 3.597 ± 1.753
0.899PhePro: 0.899 ± 1.002
3.597PheGln: 3.597 ± 1.267
5.396PheArg: 5.396 ± 2.891
0.899PheSer: 0.899 ± 0.672
3.597PheThr: 3.597 ± 2.009
1.799PheVal: 1.799 ± 0.725
0.899PheTrp: 0.899 ± 0.78
2.698PheTyr: 2.698 ± 2.34
0.0PheXaa: 0.0 ± 0.0
Gly
2.698GlyAla: 2.698 ± 2.015
1.799GlyCys: 1.799 ± 1.117
3.597GlyAsp: 3.597 ± 1.402
4.496GlyGlu: 4.496 ± 1.843
2.698GlyPhe: 2.698 ± 2.137
3.597GlyGly: 3.597 ± 1.752
1.799GlyHis: 1.799 ± 0.725
4.496GlyIle: 4.496 ± 1.316
7.194GlyLys: 7.194 ± 2.341
1.799GlyLeu: 1.799 ± 1.117
0.0GlyMet: 0.0 ± 0.0
2.698GlyAsn: 2.698 ± 2.342
3.597GlyPro: 3.597 ± 1.752
3.597GlyGln: 3.597 ± 0.913
0.899GlyArg: 0.899 ± 0.672
0.899GlySer: 0.899 ± 0.672
1.799GlyThr: 1.799 ± 1.173
2.698GlyVal: 2.698 ± 2.002
0.0GlyTrp: 0.0 ± 0.0
1.799GlyTyr: 1.799 ± 1.395
0.0GlyXaa: 0.0 ± 0.0
His
1.799HisAla: 1.799 ± 1.56
1.799HisCys: 1.799 ± 2.062
0.899HisAsp: 0.899 ± 0.966
1.799HisGlu: 1.799 ± 1.037
2.698HisPhe: 2.698 ± 2.015
1.799HisGly: 1.799 ± 1.346
1.799HisHis: 1.799 ± 2.062
1.799HisIle: 1.799 ± 0.873
1.799HisLys: 1.799 ± 1.254
2.698HisLeu: 2.698 ± 1.112
0.899HisMet: 0.899 ± 0.78
5.396HisAsn: 5.396 ± 2.956
1.799HisPro: 1.799 ± 0.979
2.698HisGln: 2.698 ± 0.859
1.799HisArg: 1.799 ± 1.117
0.0HisSer: 0.0 ± 0.0
1.799HisThr: 1.799 ± 1.56
1.799HisVal: 1.799 ± 0.979
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
0.899IleAla: 0.899 ± 1.002
0.899IleCys: 0.899 ± 0.78
2.698IleAsp: 2.698 ± 2.015
1.799IleGlu: 1.799 ± 1.043
2.698IlePhe: 2.698 ± 1.348
1.799IleGly: 1.799 ± 1.56
2.698IleHis: 2.698 ± 1.243
1.799IleIle: 1.799 ± 1.173
4.496IleLys: 4.496 ± 0.999
0.899IleLeu: 0.899 ± 0.966
0.0IleMet: 0.0 ± 0.0
0.899IleAsn: 0.899 ± 0.966
0.899IlePro: 0.899 ± 0.672
4.496IleGln: 4.496 ± 2.289
3.597IleArg: 3.597 ± 1.817
5.396IleSer: 5.396 ± 2.791
2.698IleThr: 2.698 ± 2.898
0.899IleVal: 0.899 ± 0.78
1.799IleTrp: 1.799 ± 1.173
1.799IleTyr: 1.799 ± 1.043
0.0IleXaa: 0.0 ± 0.0
Lys
2.698LysAla: 2.698 ± 2.055
3.597LysCys: 3.597 ± 1.123
3.597LysAsp: 3.597 ± 1.195
4.496LysGlu: 4.496 ± 1.665
1.799LysPhe: 1.799 ± 1.173
1.799LysGly: 1.799 ± 0.725
0.899LysHis: 0.899 ± 0.672
2.698LysIle: 2.698 ± 1.402
2.698LysLys: 2.698 ± 1.206
0.0LysLeu: 0.0 ± 0.0
0.899LysMet: 0.899 ± 1.002
4.496LysAsn: 4.496 ± 1.815
2.698LysPro: 2.698 ± 1.16
0.0LysGln: 0.0 ± 0.0
4.496LysArg: 4.496 ± 1.921
4.496LysSer: 4.496 ± 0.979
1.799LysThr: 1.799 ± 1.344
5.396LysVal: 5.396 ± 1.737
0.0LysTrp: 0.0 ± 0.0
6.295LysTyr: 6.295 ± 1.824
0.0LysXaa: 0.0 ± 0.0
Leu
1.799LeuAla: 1.799 ± 1.037
1.799LeuCys: 1.799 ± 1.344
7.194LeuAsp: 7.194 ± 2.519
4.496LeuGlu: 4.496 ± 2.12
0.0LeuPhe: 0.0 ± 0.0
7.194LeuGly: 7.194 ± 3.182
1.799LeuHis: 1.799 ± 0.979
2.698LeuIle: 2.698 ± 1.316
3.597LeuLys: 3.597 ± 1.752
2.698LeuLeu: 2.698 ± 1.653
0.0LeuMet: 0.0 ± 0.0
5.396LeuAsn: 5.396 ± 1.388
1.799LeuPro: 1.799 ± 1.269
1.799LeuGln: 1.799 ± 1.037
9.892LeuArg: 9.892 ± 3.061
4.496LeuSer: 4.496 ± 1.665
7.194LeuThr: 7.194 ± 1.461
1.799LeuVal: 1.799 ± 1.344
0.0LeuTrp: 0.0 ± 0.0
5.396LeuTyr: 5.396 ± 2.818
0.0LeuXaa: 0.0 ± 0.0
Met
4.496MetAla: 4.496 ± 1.316
0.0MetCys: 0.0 ± 0.0
2.698MetAsp: 2.698 ± 1.362
0.899MetGlu: 0.899 ± 0.672
1.799MetPhe: 1.799 ± 1.117
2.698MetGly: 2.698 ± 0.826
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
0.899MetLeu: 0.899 ± 1.002
0.0MetMet: 0.0 ± 0.0
0.899MetAsn: 0.899 ± 0.78
0.0MetPro: 0.0 ± 0.0
0.899MetGln: 0.899 ± 1.002
0.899MetArg: 0.899 ± 1.031
1.799MetSer: 1.799 ± 1.031
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
1.799MetTrp: 1.799 ± 1.037
0.899MetTyr: 0.899 ± 0.78
0.0MetXaa: 0.0 ± 0.0
Asn
2.698AsnAla: 2.698 ± 1.16
0.899AsnCys: 0.899 ± 1.031
2.698AsnAsp: 2.698 ± 1.16
1.799AsnGlu: 1.799 ± 1.205
1.799AsnPhe: 1.799 ± 1.205
1.799AsnGly: 1.799 ± 0.873
5.396AsnHis: 5.396 ± 2.811
2.698AsnIle: 2.698 ± 1.16
0.899AsnLys: 0.899 ± 0.672
6.295AsnLeu: 6.295 ± 2.123
0.899AsnMet: 0.899 ± 0.97
1.799AsnAsn: 1.799 ± 1.173
3.597AsnPro: 3.597 ± 0.983
2.698AsnGln: 2.698 ± 1.112
6.295AsnArg: 6.295 ± 1.592
1.799AsnSer: 1.799 ± 1.344
4.496AsnThr: 4.496 ± 1.621
5.396AsnVal: 5.396 ± 1.548
0.0AsnTrp: 0.0 ± 0.0
2.698AsnTyr: 2.698 ± 1.16
0.0AsnXaa: 0.0 ± 0.0
Pro
1.799ProAla: 1.799 ± 1.56
0.899ProCys: 0.899 ± 0.78
1.799ProAsp: 1.799 ± 1.117
4.496ProGlu: 4.496 ± 1.516
1.799ProPhe: 1.799 ± 0.979
2.698ProGly: 2.698 ± 0.859
2.698ProHis: 2.698 ± 2.015
2.698ProIle: 2.698 ± 1.354
3.597ProLys: 3.597 ± 1.752
5.396ProLeu: 5.396 ± 1.377
3.597ProMet: 3.597 ± 1.171
2.698ProAsn: 2.698 ± 2.015
2.698ProPro: 2.698 ± 1.962
4.496ProGln: 4.496 ± 2.686
4.496ProArg: 4.496 ± 2.271
5.396ProSer: 5.396 ± 1.846
4.496ProThr: 4.496 ± 1.51
2.698ProVal: 2.698 ± 0.859
0.0ProTrp: 0.0 ± 0.0
0.899ProTyr: 0.899 ± 1.002
0.0ProXaa: 0.0 ± 0.0
Gln
5.396GlnAla: 5.396 ± 2.891
0.0GlnCys: 0.0 ± 0.0
0.899GlnAsp: 0.899 ± 1.031
2.698GlnGlu: 2.698 ± 0.994
1.799GlnPhe: 1.799 ± 1.344
1.799GlnGly: 1.799 ± 0.979
1.799GlnHis: 1.799 ± 1.562
2.698GlnIle: 2.698 ± 2.015
1.799GlnLys: 1.799 ± 1.346
0.0GlnLeu: 0.0 ± 0.0
1.799GlnMet: 1.799 ± 1.269
3.597GlnAsn: 3.597 ± 1.981
3.597GlnPro: 3.597 ± 3.161
3.597GlnGln: 3.597 ± 0.983
1.799GlnArg: 1.799 ± 1.344
5.396GlnSer: 5.396 ± 1.616
3.597GlnThr: 3.597 ± 1.891
6.295GlnVal: 6.295 ± 3.039
0.0GlnTrp: 0.0 ± 0.0
0.899GlnTyr: 0.899 ± 0.78
0.0GlnXaa: 0.0 ± 0.0
Arg
2.698ArgAla: 2.698 ± 1.104
0.899ArgCys: 0.899 ± 1.002
3.597ArgAsp: 3.597 ± 1.456
2.698ArgGlu: 2.698 ± 1.348
7.194ArgPhe: 7.194 ± 2.823
3.597ArgGly: 3.597 ± 0.913
1.799ArgHis: 1.799 ± 1.346
3.597ArgIle: 3.597 ± 1.327
4.496ArgLys: 4.496 ± 2.343
3.597ArgLeu: 3.597 ± 2.097
1.799ArgMet: 1.799 ± 1.041
1.799ArgAsn: 1.799 ± 1.932
8.094ArgPro: 8.094 ± 2.396
1.799ArgGln: 1.799 ± 1.4
8.993ArgArg: 8.993 ± 5.247
7.194ArgSer: 7.194 ± 1.699
4.496ArgThr: 4.496 ± 1.527
5.396ArgVal: 5.396 ± 1.08
0.899ArgTrp: 0.899 ± 0.78
0.0ArgTyr: 0.0 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
5.396SerAla: 5.396 ± 1.642
1.799SerCys: 1.799 ± 2.004
4.496SerAsp: 4.496 ± 1.764
1.799SerGlu: 1.799 ± 1.043
4.496SerPhe: 4.496 ± 0.964
1.799SerGly: 1.799 ± 0.979
0.899SerHis: 0.899 ± 1.031
2.698SerIle: 2.698 ± 2.068
3.597SerLys: 3.597 ± 1.195
5.396SerLeu: 5.396 ± 1.978
1.799SerMet: 1.799 ± 1.205
5.396SerAsn: 5.396 ± 2.017
8.993SerPro: 8.993 ± 1.672
3.597SerGln: 3.597 ± 2.085
3.597SerArg: 3.597 ± 1.653
16.187SerSer: 16.187 ± 5.794
3.597SerThr: 3.597 ± 2.744
2.698SerVal: 2.698 ± 0.994
0.899SerTrp: 0.899 ± 1.031
3.597SerTyr: 3.597 ± 1.195
0.0SerXaa: 0.0 ± 0.0
Thr
4.496ThrAla: 4.496 ± 1.4
0.899ThrCys: 0.899 ± 0.781
0.0ThrAsp: 0.0 ± 0.0
3.597ThrGlu: 3.597 ± 0.995
1.799ThrPhe: 1.799 ± 1.228
5.396ThrGly: 5.396 ± 1.234
2.698ThrHis: 2.698 ± 1.627
2.698ThrIle: 2.698 ± 1.373
1.799ThrLys: 1.799 ± 1.344
4.496ThrLeu: 4.496 ± 1.277
0.899ThrMet: 0.899 ± 0.672
3.597ThrAsn: 3.597 ± 2.08
5.396ThrPro: 5.396 ± 1.652
2.698ThrGln: 2.698 ± 2.177
2.698ThrArg: 2.698 ± 1.34
3.597ThrSer: 3.597 ± 2.048
0.899ThrThr: 0.899 ± 0.781
5.396ThrVal: 5.396 ± 3.162
3.597ThrTrp: 3.597 ± 1.891
1.799ThrTyr: 1.799 ± 1.043
0.0ThrXaa: 0.0 ± 0.0
Val
1.799ValAla: 1.799 ± 0.725
0.899ValCys: 0.899 ± 0.672
1.799ValAsp: 1.799 ± 1.043
0.899ValGlu: 0.899 ± 0.672
2.698ValPhe: 2.698 ± 1.354
1.799ValGly: 1.799 ± 1.56
0.899ValHis: 0.899 ± 1.002
4.496ValIle: 4.496 ± 2.674
4.496ValLys: 4.496 ± 2.113
8.993ValLeu: 8.993 ± 2.25
0.899ValMet: 0.899 ± 0.78
0.899ValAsn: 0.899 ± 0.78
3.597ValPro: 3.597 ± 1.754
6.295ValGln: 6.295 ± 1.352
3.597ValArg: 3.597 ± 1.479
4.496ValSer: 4.496 ± 1.996
3.597ValThr: 3.597 ± 2.08
2.698ValVal: 2.698 ± 1.16
0.0ValTrp: 0.0 ± 0.0
5.396ValTyr: 5.396 ± 1.913
0.0ValXaa: 0.0 ± 0.0
Trp
2.698TrpAla: 2.698 ± 2.015
0.0TrpCys: 0.0 ± 0.0
1.799TrpAsp: 1.799 ± 1.254
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.899TrpGly: 0.899 ± 0.672
0.0TrpHis: 0.0 ± 0.0
0.899TrpIle: 0.899 ± 0.78
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.899TrpMet: 0.899 ± 0.78
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.899TrpGln: 0.899 ± 0.672
1.799TrpArg: 1.799 ± 1.395
0.899TrpSer: 0.899 ± 0.781
1.799TrpThr: 1.799 ± 1.173
0.899TrpVal: 0.899 ± 1.031
0.0TrpTrp: 0.0 ± 0.0
0.899TrpTyr: 0.899 ± 0.672
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.698TyrAla: 2.698 ± 1.348
1.799TyrCys: 1.799 ± 1.037
1.799TyrAsp: 1.799 ± 1.56
1.799TyrGlu: 1.799 ± 1.205
4.496TyrPhe: 4.496 ± 1.316
2.698TyrGly: 2.698 ± 1.206
0.0TyrHis: 0.0 ± 0.0
2.698TyrIle: 2.698 ± 1.373
1.799TyrLys: 1.799 ± 1.344
4.496TyrLeu: 4.496 ± 1.401
2.698TyrMet: 2.698 ± 1.295
3.597TyrAsn: 3.597 ± 1.015
0.899TyrPro: 0.899 ± 0.672
0.0TyrGln: 0.0 ± 0.0
2.698TyrArg: 2.698 ± 2.34
2.698TyrSer: 2.698 ± 1.16
0.899TyrThr: 0.899 ± 0.966
4.496TyrVal: 4.496 ± 1.876
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1113 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski