Amino acid dipepetide frequency for Wuhan spider virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.336AlaAla: 5.336 ± 0.0
0.314AlaCys: 0.314 ± 0.0
4.394AlaAsp: 4.394 ± 0.0
7.533AlaGlu: 7.533 ± 0.0
5.65AlaPhe: 5.65 ± 0.0
2.511AlaGly: 2.511 ± 0.0
2.197AlaHis: 2.197 ± 0.0
5.964AlaIle: 5.964 ± 0.0
2.825AlaLys: 2.825 ± 0.0
4.08AlaLeu: 4.08 ± 0.0
1.255AlaMet: 1.255 ± 0.0
4.08AlaAsn: 4.08 ± 0.0
2.511AlaPro: 2.511 ± 0.0
1.883AlaGln: 1.883 ± 0.0
3.139AlaArg: 3.139 ± 0.0
4.394AlaSer: 4.394 ± 0.0
3.766AlaThr: 3.766 ± 0.0
4.708AlaVal: 4.708 ± 0.0
0.628AlaTrp: 0.628 ± 0.0
1.883AlaTyr: 1.883 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.942CysAla: 0.942 ± 0.0
0.628CysCys: 0.628 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.628CysGlu: 0.628 ± 0.0
0.314CysPhe: 0.314 ± 0.0
1.569CysGly: 1.569 ± 0.0
0.314CysHis: 0.314 ± 0.0
0.942CysIle: 0.942 ± 0.0
1.883CysLys: 1.883 ± 0.0
1.255CysLeu: 1.255 ± 0.0
0.628CysMet: 0.628 ± 0.0
0.314CysAsn: 0.314 ± 0.0
0.628CysPro: 0.628 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.942CysArg: 0.942 ± 0.0
2.197CysSer: 2.197 ± 0.0
2.197CysThr: 2.197 ± 0.0
0.628CysVal: 0.628 ± 0.0
0.628CysTrp: 0.628 ± 0.0
1.883CysTyr: 1.883 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.511AspAla: 2.511 ± 0.0
1.255AspCys: 1.255 ± 0.0
3.453AspAsp: 3.453 ± 0.0
1.883AspGlu: 1.883 ± 0.0
3.453AspPhe: 3.453 ± 0.0
2.825AspGly: 2.825 ± 0.0
0.942AspHis: 0.942 ± 0.0
2.511AspIle: 2.511 ± 0.0
4.394AspLys: 4.394 ± 0.0
6.277AspLeu: 6.277 ± 0.0
0.314AspMet: 0.314 ± 0.0
4.708AspAsn: 4.708 ± 0.0
2.197AspPro: 2.197 ± 0.0
1.569AspGln: 1.569 ± 0.0
1.883AspArg: 1.883 ± 0.0
4.708AspSer: 4.708 ± 0.0
2.825AspThr: 2.825 ± 0.0
3.139AspVal: 3.139 ± 0.0
0.0AspTrp: 0.0 ± 0.0
2.825AspTyr: 2.825 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
3.453GluAla: 3.453 ± 0.0
0.628GluCys: 0.628 ± 0.0
3.139GluAsp: 3.139 ± 0.0
3.766GluGlu: 3.766 ± 0.0
3.766GluPhe: 3.766 ± 0.0
4.708GluGly: 4.708 ± 0.0
1.255GluHis: 1.255 ± 0.0
2.511GluIle: 2.511 ± 0.0
5.964GluLys: 5.964 ± 0.0
5.65GluLeu: 5.65 ± 0.0
2.197GluMet: 2.197 ± 0.0
2.197GluAsn: 2.197 ± 0.0
1.883GluPro: 1.883 ± 0.0
2.197GluGln: 2.197 ± 0.0
2.511GluArg: 2.511 ± 0.0
3.766GluSer: 3.766 ± 0.0
3.453GluThr: 3.453 ± 0.0
3.139GluVal: 3.139 ± 0.0
1.569GluTrp: 1.569 ± 0.0
0.942GluTyr: 0.942 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
3.766PheAla: 3.766 ± 0.0
0.628PheCys: 0.628 ± 0.0
3.139PheAsp: 3.139 ± 0.0
3.139PheGlu: 3.139 ± 0.0
3.453PhePhe: 3.453 ± 0.0
3.453PheGly: 3.453 ± 0.0
0.628PheHis: 0.628 ± 0.0
4.08PheIle: 4.08 ± 0.0
4.708PheLys: 4.708 ± 0.0
3.766PheLeu: 3.766 ± 0.0
0.942PheMet: 0.942 ± 0.0
4.394PheAsn: 4.394 ± 0.0
3.139PhePro: 3.139 ± 0.0
1.883PheGln: 1.883 ± 0.0
2.197PheArg: 2.197 ± 0.0
4.708PheSer: 4.708 ± 0.0
3.766PheThr: 3.766 ± 0.0
5.964PheVal: 5.964 ± 0.0
1.255PheTrp: 1.255 ± 0.0
1.569PheTyr: 1.569 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
4.394GlyAla: 4.394 ± 0.0
1.255GlyCys: 1.255 ± 0.0
5.65GlyAsp: 5.65 ± 0.0
5.336GlyGlu: 5.336 ± 0.0
2.825GlyPhe: 2.825 ± 0.0
2.197GlyGly: 2.197 ± 0.0
1.255GlyHis: 1.255 ± 0.0
5.022GlyIle: 5.022 ± 0.0
3.453GlyLys: 3.453 ± 0.0
2.511GlyLeu: 2.511 ± 0.0
2.197GlyMet: 2.197 ± 0.0
3.766GlyAsn: 3.766 ± 0.0
1.569GlyPro: 1.569 ± 0.0
1.569GlyGln: 1.569 ± 0.0
2.511GlyArg: 2.511 ± 0.0
5.022GlySer: 5.022 ± 0.0
1.255GlyThr: 1.255 ± 0.0
2.197GlyVal: 2.197 ± 0.0
0.942GlyTrp: 0.942 ± 0.0
2.197GlyTyr: 2.197 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.255HisAla: 1.255 ± 0.0
0.314HisCys: 0.314 ± 0.0
0.942HisAsp: 0.942 ± 0.0
0.314HisGlu: 0.314 ± 0.0
0.942HisPhe: 0.942 ± 0.0
0.942HisGly: 0.942 ± 0.0
0.628HisHis: 0.628 ± 0.0
0.314HisIle: 0.314 ± 0.0
0.942HisLys: 0.942 ± 0.0
3.139HisLeu: 3.139 ± 0.0
0.314HisMet: 0.314 ± 0.0
0.942HisAsn: 0.942 ± 0.0
0.314HisPro: 0.314 ± 0.0
0.314HisGln: 0.314 ± 0.0
1.883HisArg: 1.883 ± 0.0
1.883HisSer: 1.883 ± 0.0
0.628HisThr: 0.628 ± 0.0
2.197HisVal: 2.197 ± 0.0
1.255HisTrp: 1.255 ± 0.0
0.942HisTyr: 0.942 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
5.964IleAla: 5.964 ± 0.0
0.942IleCys: 0.942 ± 0.0
1.883IleAsp: 1.883 ± 0.0
2.197IleGlu: 2.197 ± 0.0
3.453IlePhe: 3.453 ± 0.0
4.394IleGly: 4.394 ± 0.0
1.883IleHis: 1.883 ± 0.0
3.453IleIle: 3.453 ± 0.0
6.905IleLys: 6.905 ± 0.0
5.65IleLeu: 5.65 ± 0.0
2.511IleMet: 2.511 ± 0.0
2.511IleAsn: 2.511 ± 0.0
4.708IlePro: 4.708 ± 0.0
0.942IleGln: 0.942 ± 0.0
3.453IleArg: 3.453 ± 0.0
5.336IleSer: 5.336 ± 0.0
3.139IleThr: 3.139 ± 0.0
3.139IleVal: 3.139 ± 0.0
0.628IleTrp: 0.628 ± 0.0
1.883IleTyr: 1.883 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
3.139LysAla: 3.139 ± 0.0
1.255LysCys: 1.255 ± 0.0
5.65LysAsp: 5.65 ± 0.0
4.08LysGlu: 4.08 ± 0.0
5.964LysPhe: 5.964 ± 0.0
1.569LysGly: 1.569 ± 0.0
1.255LysHis: 1.255 ± 0.0
7.533LysIle: 7.533 ± 0.0
2.197LysLys: 2.197 ± 0.0
5.336LysLeu: 5.336 ± 0.0
1.569LysMet: 1.569 ± 0.0
3.139LysAsn: 3.139 ± 0.0
4.394LysPro: 4.394 ± 0.0
3.453LysGln: 3.453 ± 0.0
3.139LysArg: 3.139 ± 0.0
5.022LysSer: 5.022 ± 0.0
2.511LysThr: 2.511 ± 0.0
3.139LysVal: 3.139 ± 0.0
0.942LysTrp: 0.942 ± 0.0
2.197LysTyr: 2.197 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
6.277LeuAla: 6.277 ± 0.0
0.942LeuCys: 0.942 ± 0.0
5.022LeuAsp: 5.022 ± 0.0
7.533LeuGlu: 7.533 ± 0.0
2.825LeuPhe: 2.825 ± 0.0
4.08LeuGly: 4.08 ± 0.0
0.628LeuHis: 0.628 ± 0.0
4.08LeuIle: 4.08 ± 0.0
6.905LeuLys: 6.905 ± 0.0
6.277LeuLeu: 6.277 ± 0.0
0.942LeuMet: 0.942 ± 0.0
4.708LeuAsn: 4.708 ± 0.0
4.708LeuPro: 4.708 ± 0.0
4.08LeuGln: 4.08 ± 0.0
4.394LeuArg: 4.394 ± 0.0
5.022LeuSer: 5.022 ± 0.0
4.708LeuThr: 4.708 ± 0.0
5.964LeuVal: 5.964 ± 0.0
0.942LeuTrp: 0.942 ± 0.0
2.197LeuTyr: 2.197 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
3.139MetAla: 3.139 ± 0.0
0.628MetCys: 0.628 ± 0.0
1.883MetAsp: 1.883 ± 0.0
1.255MetGlu: 1.255 ± 0.0
1.883MetPhe: 1.883 ± 0.0
1.255MetGly: 1.255 ± 0.0
0.942MetHis: 0.942 ± 0.0
1.255MetIle: 1.255 ± 0.0
0.314MetLys: 0.314 ± 0.0
1.883MetLeu: 1.883 ± 0.0
0.0MetMet: 0.0 ± 0.0
0.942MetAsn: 0.942 ± 0.0
1.883MetPro: 1.883 ± 0.0
0.628MetGln: 0.628 ± 0.0
1.255MetArg: 1.255 ± 0.0
0.628MetSer: 0.628 ± 0.0
1.255MetThr: 1.255 ± 0.0
0.628MetVal: 0.628 ± 0.0
0.314MetTrp: 0.314 ± 0.0
1.255MetTyr: 1.255 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.139AsnAla: 3.139 ± 0.0
1.883AsnCys: 1.883 ± 0.0
1.569AsnAsp: 1.569 ± 0.0
1.569AsnGlu: 1.569 ± 0.0
2.825AsnPhe: 2.825 ± 0.0
3.453AsnGly: 3.453 ± 0.0
1.883AsnHis: 1.883 ± 0.0
2.511AsnIle: 2.511 ± 0.0
3.139AsnLys: 3.139 ± 0.0
5.022AsnLeu: 5.022 ± 0.0
2.197AsnMet: 2.197 ± 0.0
2.197AsnAsn: 2.197 ± 0.0
4.08AsnPro: 4.08 ± 0.0
1.569AsnGln: 1.569 ± 0.0
2.511AsnArg: 2.511 ± 0.0
5.65AsnSer: 5.65 ± 0.0
1.883AsnThr: 1.883 ± 0.0
2.197AsnVal: 2.197 ± 0.0
2.197AsnTrp: 2.197 ± 0.0
2.511AsnTyr: 2.511 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.453ProAla: 3.453 ± 0.0
0.628ProCys: 0.628 ± 0.0
2.511ProAsp: 2.511 ± 0.0
2.825ProGlu: 2.825 ± 0.0
3.766ProPhe: 3.766 ± 0.0
1.883ProGly: 1.883 ± 0.0
0.628ProHis: 0.628 ± 0.0
4.708ProIle: 4.708 ± 0.0
3.453ProLys: 3.453 ± 0.0
3.139ProLeu: 3.139 ± 0.0
1.883ProMet: 1.883 ± 0.0
0.942ProAsn: 0.942 ± 0.0
3.139ProPro: 3.139 ± 0.0
1.569ProGln: 1.569 ± 0.0
3.139ProArg: 3.139 ± 0.0
4.394ProSer: 4.394 ± 0.0
2.197ProThr: 2.197 ± 0.0
3.453ProVal: 3.453 ± 0.0
0.314ProTrp: 0.314 ± 0.0
3.453ProTyr: 3.453 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
1.569GlnAla: 1.569 ± 0.0
0.942GlnCys: 0.942 ± 0.0
0.628GlnAsp: 0.628 ± 0.0
1.883GlnGlu: 1.883 ± 0.0
3.453GlnPhe: 3.453 ± 0.0
3.453GlnGly: 3.453 ± 0.0
0.942GlnHis: 0.942 ± 0.0
1.255GlnIle: 1.255 ± 0.0
1.255GlnLys: 1.255 ± 0.0
4.394GlnLeu: 4.394 ± 0.0
1.569GlnMet: 1.569 ± 0.0
2.197GlnAsn: 2.197 ± 0.0
0.942GlnPro: 0.942 ± 0.0
0.942GlnGln: 0.942 ± 0.0
1.883GlnArg: 1.883 ± 0.0
0.942GlnSer: 0.942 ± 0.0
0.942GlnThr: 0.942 ± 0.0
1.255GlnVal: 1.255 ± 0.0
0.942GlnTrp: 0.942 ± 0.0
1.255GlnTyr: 1.255 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.197ArgAla: 2.197 ± 0.0
1.569ArgCys: 1.569 ± 0.0
2.825ArgAsp: 2.825 ± 0.0
2.511ArgGlu: 2.511 ± 0.0
1.569ArgPhe: 1.569 ± 0.0
4.08ArgGly: 4.08 ± 0.0
0.0ArgHis: 0.0 ± 0.0
3.139ArgIle: 3.139 ± 0.0
2.825ArgLys: 2.825 ± 0.0
4.708ArgLeu: 4.708 ± 0.0
1.569ArgMet: 1.569 ± 0.0
3.139ArgAsn: 3.139 ± 0.0
2.197ArgPro: 2.197 ± 0.0
2.197ArgGln: 2.197 ± 0.0
4.394ArgArg: 4.394 ± 0.0
2.511ArgSer: 2.511 ± 0.0
1.255ArgThr: 1.255 ± 0.0
4.08ArgVal: 4.08 ± 0.0
1.255ArgTrp: 1.255 ± 0.0
1.255ArgTyr: 1.255 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
3.766SerAla: 3.766 ± 0.0
1.883SerCys: 1.883 ± 0.0
4.08SerAsp: 4.08 ± 0.0
4.08SerGlu: 4.08 ± 0.0
5.964SerPhe: 5.964 ± 0.0
2.825SerGly: 2.825 ± 0.0
1.569SerHis: 1.569 ± 0.0
5.022SerIle: 5.022 ± 0.0
5.65SerLys: 5.65 ± 0.0
6.905SerLeu: 6.905 ± 0.0
1.883SerMet: 1.883 ± 0.0
5.65SerAsn: 5.65 ± 0.0
4.394SerPro: 4.394 ± 0.0
0.942SerGln: 0.942 ± 0.0
2.825SerArg: 2.825 ± 0.0
6.905SerSer: 6.905 ± 0.0
3.139SerThr: 3.139 ± 0.0
4.08SerVal: 4.08 ± 0.0
1.569SerTrp: 1.569 ± 0.0
2.197SerTyr: 2.197 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
3.453ThrAla: 3.453 ± 0.0
0.314ThrCys: 0.314 ± 0.0
0.628ThrAsp: 0.628 ± 0.0
1.883ThrGlu: 1.883 ± 0.0
2.511ThrPhe: 2.511 ± 0.0
4.394ThrGly: 4.394 ± 0.0
0.942ThrHis: 0.942 ± 0.0
4.394ThrIle: 4.394 ± 0.0
2.197ThrLys: 2.197 ± 0.0
3.453ThrLeu: 3.453 ± 0.0
0.628ThrMet: 0.628 ± 0.0
1.255ThrAsn: 1.255 ± 0.0
2.825ThrPro: 2.825 ± 0.0
1.255ThrGln: 1.255 ± 0.0
2.197ThrArg: 2.197 ± 0.0
4.08ThrSer: 4.08 ± 0.0
2.825ThrThr: 2.825 ± 0.0
3.766ThrVal: 3.766 ± 0.0
1.255ThrTrp: 1.255 ± 0.0
2.197ThrTyr: 2.197 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
7.219ValAla: 7.219 ± 0.0
0.628ValCys: 0.628 ± 0.0
4.08ValAsp: 4.08 ± 0.0
4.08ValGlu: 4.08 ± 0.0
2.511ValPhe: 2.511 ± 0.0
4.08ValGly: 4.08 ± 0.0
1.569ValHis: 1.569 ± 0.0
3.766ValIle: 3.766 ± 0.0
4.08ValLys: 4.08 ± 0.0
5.65ValLeu: 5.65 ± 0.0
0.314ValMet: 0.314 ± 0.0
3.453ValAsn: 3.453 ± 0.0
3.766ValPro: 3.766 ± 0.0
1.883ValGln: 1.883 ± 0.0
2.197ValArg: 2.197 ± 0.0
3.453ValSer: 3.453 ± 0.0
1.569ValThr: 1.569 ± 0.0
5.022ValVal: 5.022 ± 0.0
0.628ValTrp: 0.628 ± 0.0
0.942ValTyr: 0.942 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
1.255TrpAla: 1.255 ± 0.0
0.628TrpCys: 0.628 ± 0.0
1.255TrpAsp: 1.255 ± 0.0
0.942TrpGlu: 0.942 ± 0.0
2.197TrpPhe: 2.197 ± 0.0
0.314TrpGly: 0.314 ± 0.0
0.314TrpHis: 0.314 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.883TrpLys: 1.883 ± 0.0
0.942TrpLeu: 0.942 ± 0.0
0.0TrpMet: 0.0 ± 0.0
1.255TrpAsn: 1.255 ± 0.0
0.628TrpPro: 0.628 ± 0.0
1.255TrpGln: 1.255 ± 0.0
1.569TrpArg: 1.569 ± 0.0
1.569TrpSer: 1.569 ± 0.0
0.942TrpThr: 0.942 ± 0.0
0.942TrpVal: 0.942 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.628TrpTyr: 0.628 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.825TyrAla: 2.825 ± 0.0
1.255TyrCys: 1.255 ± 0.0
0.942TyrAsp: 0.942 ± 0.0
1.255TyrGlu: 1.255 ± 0.0
1.255TyrPhe: 1.255 ± 0.0
3.139TyrGly: 3.139 ± 0.0
0.628TyrHis: 0.628 ± 0.0
2.511TyrIle: 2.511 ± 0.0
2.825TyrLys: 2.825 ± 0.0
2.197TyrLeu: 2.197 ± 0.0
0.0TyrMet: 0.0 ± 0.0
2.197TyrAsn: 2.197 ± 0.0
1.569TyrPro: 1.569 ± 0.0
2.511TyrGln: 2.511 ± 0.0
1.255TyrArg: 1.255 ± 0.0
3.139TyrSer: 3.139 ± 0.0
2.197TyrThr: 2.197 ± 0.0
1.255TyrVal: 1.255 ± 0.0
1.255TyrTrp: 1.255 ± 0.0
1.255TyrTyr: 1.255 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (3187 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski