Amino acid dipepetide frequency for Caminicella sporogenes DSM 14501

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	3.876AlaAla: 3.876 ± 0.109	0.59AlaCys: 0.59 ± 0.029	2.584AlaAsp: 2.584 ± 0.064	3.468AlaGlu: 3.468 ± 0.079	2.27AlaPhe: 2.27 ± 0.076	3.914AlaGly: 3.914 ± 0.093	0.84AlaHis: 0.84 ± 0.038	5.664AlaIle: 5.664 ± 0.1	5.115AlaLys: 5.115 ± 0.103	5.478AlaLeu: 5.478 ± 0.103	1.515AlaMet: 1.515 ± 0.053	2.514AlaAsn: 2.514 ± 0.067	1.339AlaPro: 1.339 ± 0.049	1.437AlaGln: 1.437 ± 0.049	2.079AlaArg: 2.079 ± 0.047	2.958AlaSer: 2.958 ± 0.067	2.466AlaThr: 2.466 ± 0.071	4.632AlaVal: 4.632 ± 0.08	0.32AlaTrp: 0.32 ± 0.022	1.975AlaTyr: 1.975 ± 0.049	0.0AlaXaa: 0.0 ± 0.0
Cys	0.48CysAla: 0.48 ± 0.026	0.126CysCys: 0.126 ± 0.014	0.534CysAsp: 0.534 ± 0.028	0.669CysGlu: 0.669 ± 0.035	0.444CysPhe: 0.444 ± 0.027	0.948CysGly: 0.948 ± 0.041	0.187CysHis: 0.187 ± 0.015	1.02CysIle: 1.02 ± 0.04	0.837CysLys: 0.837 ± 0.034	0.726CysLeu: 0.726 ± 0.031	0.223CysMet: 0.223 ± 0.019	0.511CysAsn: 0.511 ± 0.025	0.438CysPro: 0.438 ± 0.026	0.186CysGln: 0.186 ± 0.017	0.434CysArg: 0.434 ± 0.024	0.643CysSer: 0.643 ± 0.036	0.432CysThr: 0.432 ± 0.028	0.532CysVal: 0.532 ± 0.027	0.065CysTrp: 0.065 ± 0.01	0.367CysTyr: 0.367 ± 0.022	0.0CysXaa: 0.0 ± 0.0
Asp	2.381AspAla: 2.381 ± 0.064	0.528AspCys: 0.528 ± 0.028	2.714AspAsp: 2.714 ± 0.08	4.867AspGlu: 4.867 ± 0.093	2.751AspPhe: 2.751 ± 0.067	3.12AspGly: 3.12 ± 0.091	0.435AspHis: 0.435 ± 0.026	6.863AspIle: 6.863 ± 0.117	5.973AspLys: 5.973 ± 0.101	4.813AspLeu: 4.813 ± 0.079	1.523AspMet: 1.523 ± 0.042	2.918AspAsn: 2.918 ± 0.075	1.252AspPro: 1.252 ± 0.048	0.552AspGln: 0.552 ± 0.026	2.087AspArg: 2.087 ± 0.053	2.69AspSer: 2.69 ± 0.068	2.166AspThr: 2.166 ± 0.053	3.749AspVal: 3.749 ± 0.069	0.388AspTrp: 0.388 ± 0.025	2.645AspTyr: 2.645 ± 0.066	0.0AspXaa: 0.0 ± 0.0
Glu	4.04GluAla: 4.04 ± 0.084	0.567GluCys: 0.567 ± 0.029	4.083GluAsp: 4.083 ± 0.081	6.99GluGlu: 6.99 ± 0.12	2.997GluPhe: 2.997 ± 0.066	4.144GluGly: 4.144 ± 0.087	0.904GluHis: 0.904 ± 0.037	9.022GluIle: 9.022 ± 0.134	9.327GluLys: 9.327 ± 0.14	6.542GluLeu: 6.542 ± 0.103	2.092GluMet: 2.092 ± 0.062	5.385GluAsn: 5.385 ± 0.097	1.418GluPro: 1.418 ± 0.047	1.605GluGln: 1.605 ± 0.054	2.947GluArg: 2.947 ± 0.071	3.113GluSer: 3.113 ± 0.068	2.808GluThr: 2.808 ± 0.066	5.249GluVal: 5.249 ± 0.089	0.395GluTrp: 0.395 ± 0.023	3.069GluTyr: 3.069 ± 0.071	0.0GluXaa: 0.0 ± 0.0
Phe	2.244PheAla: 2.244 ± 0.066	0.471PheCys: 0.471 ± 0.026	2.55PheAsp: 2.55 ± 0.066	3.033PheGlu: 3.033 ± 0.079	1.97PhePhe: 1.97 ± 0.073	2.902PheGly: 2.902 ± 0.072	0.539PheHis: 0.539 ± 0.028	4.831PheIle: 4.831 ± 0.101	4.187PheLys: 4.187 ± 0.08	3.952PheLeu: 3.952 ± 0.085	1.102PheMet: 1.102 ± 0.04	2.656PheAsn: 2.656 ± 0.056	1.229PhePro: 1.229 ± 0.043	0.888PheGln: 0.888 ± 0.038	1.293PheArg: 1.293 ± 0.044	2.79PheSer: 2.79 ± 0.064	2.257PheThr: 2.257 ± 0.066	2.545PheVal: 2.545 ± 0.07	0.273PheTrp: 0.273 ± 0.023	1.774PheTyr: 1.774 ± 0.057	0.0PheXaa: 0.0 ± 0.0
Gly	4.02GlyAla: 4.02 ± 0.115	0.762GlyCys: 0.762 ± 0.038	3.012GlyAsp: 3.012 ± 0.067	4.027GlyGlu: 4.027 ± 0.088	3.121GlyPhe: 3.121 ± 0.063	4.157GlyGly: 4.157 ± 0.094	0.965GlyHis: 0.965 ± 0.037	7.436GlyIle: 7.436 ± 0.117	6.059GlyLys: 6.059 ± 0.095	5.594GlyLeu: 5.594 ± 0.091	1.677GlyMet: 1.677 ± 0.055	3.002GlyAsn: 3.002 ± 0.065	1.356GlyPro: 1.356 ± 0.044	1.505GlyGln: 1.505 ± 0.055	2.512GlyArg: 2.512 ± 0.065	3.174GlySer: 3.174 ± 0.07	3.209GlyThr: 3.209 ± 0.073	4.307GlyVal: 4.307 ± 0.098	0.473GlyTrp: 0.473 ± 0.03	2.912GlyTyr: 2.912 ± 0.06	0.0GlyXaa: 0.0 ± 0.0
His	0.715HisAla: 0.715 ± 0.033	0.148HisCys: 0.148 ± 0.016	0.651HisAsp: 0.651 ± 0.031	0.919HisGlu: 0.919 ± 0.036	0.66HisPhe: 0.66 ± 0.031	0.937HisGly: 0.937 ± 0.036	0.317HisHis: 0.317 ± 0.021	1.471HisIle: 1.471 ± 0.045	1.062HisLys: 1.062 ± 0.04	1.182HisLeu: 1.182 ± 0.04	0.316HisMet: 0.316 ± 0.022	0.748HisAsn: 0.748 ± 0.03	0.736HisPro: 0.736 ± 0.032	0.309HisGln: 0.309 ± 0.02	0.561HisArg: 0.561 ± 0.03	0.8HisSer: 0.8 ± 0.035	0.642HisThr: 0.642 ± 0.031	0.78HisVal: 0.78 ± 0.035	0.104HisTrp: 0.104 ± 0.011	0.539HisTyr: 0.539 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	6.244IleAla: 6.244 ± 0.1	1.103IleCys: 1.103 ± 0.039	6.93IleAsp: 6.93 ± 0.12	8.411IleGlu: 8.411 ± 0.114	4.679IlePhe: 4.679 ± 0.097	6.764IleGly: 6.764 ± 0.125	1.403IleHis: 1.403 ± 0.051	10.834IleIle: 10.834 ± 0.153	10.648IleLys: 10.648 ± 0.135	10.049IleLeu: 10.049 ± 0.127	2.288IleMet: 2.288 ± 0.055	6.637IleAsn: 6.637 ± 0.092	3.781IlePro: 3.781 ± 0.062	2.273IleGln: 2.273 ± 0.053	3.679IleArg: 3.679 ± 0.072	6.723IleSer: 6.723 ± 0.107	4.767IleThr: 4.767 ± 0.083	6.62IleVal: 6.62 ± 0.105	0.531IleTrp: 0.531 ± 0.029	3.956IleTyr: 3.956 ± 0.071	0.0IleXaa: 0.0 ± 0.0
Lys	5.19LysAla: 5.19 ± 0.096	0.787LysCys: 0.787 ± 0.037	5.763LysAsp: 5.763 ± 0.106	9.503LysGlu: 9.503 ± 0.137	3.699LysPhe: 3.699 ± 0.073	5.478LysGly: 5.478 ± 0.094	1.221LysHis: 1.221 ± 0.043	10.799LysIle: 10.799 ± 0.119	10.421LysLys: 10.421 ± 0.141	8.592LysLeu: 8.592 ± 0.125	2.55LysMet: 2.55 ± 0.06	7.015LysAsn: 7.015 ± 0.127	2.469LysPro: 2.469 ± 0.063	2.324LysGln: 2.324 ± 0.057	3.882LysArg: 3.882 ± 0.073	5.015LysSer: 5.015 ± 0.083	4.304LysThr: 4.304 ± 0.077	6.547LysVal: 6.547 ± 0.11	0.633LysTrp: 0.633 ± 0.03	4.734LysTyr: 4.734 ± 0.094	0.0LysXaa: 0.0 ± 0.0
Leu	5.087LeuAla: 5.087 ± 0.103	0.89LeuCys: 0.89 ± 0.039	5.09LeuAsp: 5.09 ± 0.09	6.698LeuGlu: 6.698 ± 0.13	3.634LeuPhe: 3.634 ± 0.077	5.892LeuGly: 5.892 ± 0.113	1.124LeuHis: 1.124 ± 0.041	8.756LeuIle: 8.756 ± 0.129	9.791LeuLys: 9.791 ± 0.126	7.669LeuLeu: 7.669 ± 0.131	2.184LeuMet: 2.184 ± 0.064	5.736LeuAsn: 5.736 ± 0.104	2.818LeuPro: 2.818 ± 0.064	1.953LeuGln: 1.953 ± 0.06	3.261LeuArg: 3.261 ± 0.077	6.071LeuSer: 6.071 ± 0.092	4.239LeuThr: 4.239 ± 0.078	5.266LeuVal: 5.266 ± 0.081	0.482LeuTrp: 0.482 ± 0.028	3.079LeuTyr: 3.079 ± 0.069	0.0LeuXaa: 0.0 ± 0.0
Met	1.825MetAla: 1.825 ± 0.053	0.194MetCys: 0.194 ± 0.016	1.378MetAsp: 1.378 ± 0.045	1.784MetGlu: 1.784 ± 0.055	0.977MetPhe: 0.977 ± 0.038	1.781MetGly: 1.781 ± 0.061	0.317MetHis: 0.317 ± 0.025	2.452MetIle: 2.452 ± 0.065	2.556MetLys: 2.556 ± 0.059	2.02MetLeu: 2.02 ± 0.054	0.639MetMet: 0.639 ± 0.032	1.521MetAsn: 1.521 ± 0.047	0.865MetPro: 0.865 ± 0.038	0.617MetGln: 0.617 ± 0.029	0.894MetArg: 0.894 ± 0.035	1.544MetSer: 1.544 ± 0.044	1.17MetThr: 1.17 ± 0.046	1.461MetVal: 1.461 ± 0.045	0.147MetTrp: 0.147 ± 0.013	0.809MetTyr: 0.809 ± 0.034	0.0MetXaa: 0.0 ± 0.0
Asn	2.606AsnAla: 2.606 ± 0.059	0.567AsnCys: 0.567 ± 0.03	2.793AsnAsp: 2.793 ± 0.071	4.119AsnGlu: 4.119 ± 0.077	2.563AsnPhe: 2.563 ± 0.071	3.345AsnGly: 3.345 ± 0.081	0.762AsnHis: 0.762 ± 0.033	7.454AsnIle: 7.454 ± 0.11	6.236AsnLys: 6.236 ± 0.118	5.83AsnLeu: 5.83 ± 0.096	1.572AsnMet: 1.572 ± 0.042	3.808AsnAsn: 3.808 ± 0.098	2.128AsnPro: 2.128 ± 0.055	1.284AsnGln: 1.284 ± 0.043	2.226AsnArg: 2.226 ± 0.06	3.449AsnSer: 3.449 ± 0.078	2.588AsnThr: 2.588 ± 0.059	3.425AsnVal: 3.425 ± 0.07	0.381AsnTrp: 0.381 ± 0.026	2.488AsnTyr: 2.488 ± 0.058	0.0AsnXaa: 0.0 ± 0.0
Pro	1.471ProAla: 1.471 ± 0.056	0.277ProCys: 0.277 ± 0.018	1.593ProAsp: 1.593 ± 0.046	2.345ProGlu: 2.345 ± 0.06	1.466ProPhe: 1.466 ± 0.052	1.831ProGly: 1.831 ± 0.057	0.55ProHis: 0.55 ± 0.027	3.056ProIle: 3.056 ± 0.065	2.456ProLys: 2.456 ± 0.056	2.563ProLeu: 2.563 ± 0.073	0.714ProMet: 0.714 ± 0.034	1.685ProAsn: 1.685 ± 0.052	0.779ProPro: 0.779 ± 0.038	0.712ProGln: 0.712 ± 0.032	0.931ProArg: 0.931 ± 0.037	1.644ProSer: 1.644 ± 0.053	1.415ProThr: 1.415 ± 0.048	2.212ProVal: 2.212 ± 0.062	0.22ProTrp: 0.22 ± 0.016	1.306ProTyr: 1.306 ± 0.05	0.0ProXaa: 0.0 ± 0.0
Gln	1.247GlnAla: 1.247 ± 0.044	0.182GlnCys: 0.182 ± 0.016	0.984GlnAsp: 0.984 ± 0.039	1.536GlnGlu: 1.536 ± 0.05	0.879GlnPhe: 0.879 ± 0.034	1.317GlnGly: 1.317 ± 0.039	0.295GlnHis: 0.295 ± 0.022	2.467GlnIle: 2.467 ± 0.061	2.204GlnLys: 2.204 ± 0.055	1.941GlnLeu: 1.941 ± 0.052	0.608GlnMet: 0.608 ± 0.03	1.48GlnAsn: 1.48 ± 0.048	0.585GlnPro: 0.585 ± 0.032	0.654GlnGln: 0.654 ± 0.031	0.986GlnArg: 0.986 ± 0.044	1.135GlnSer: 1.135 ± 0.045	0.9GlnThr: 0.9 ± 0.038	1.367GlnVal: 1.367 ± 0.043	0.151GlnTrp: 0.151 ± 0.015	0.9GlnTyr: 0.9 ± 0.037	0.0GlnXaa: 0.0 ± 0.0
Arg	2.146ArgAla: 2.146 ± 0.058	0.381ArgCys: 0.381 ± 0.024	1.996ArgAsp: 1.996 ± 0.056	3.691ArgGlu: 3.691 ± 0.079	1.62ArgPhe: 1.62 ± 0.049	2.311ArgGly: 2.311 ± 0.063	0.572ArgHis: 0.572 ± 0.03	3.424ArgIle: 3.424 ± 0.075	3.838ArgLys: 3.838 ± 0.082	3.318ArgLeu: 3.318 ± 0.076	0.948ArgMet: 0.948 ± 0.044	2.121ArgAsn: 2.121 ± 0.052	1.088ArgPro: 1.088 ± 0.04	1.005ArgGln: 1.005 ± 0.033	1.731ArgArg: 1.731 ± 0.056	1.401ArgSer: 1.401 ± 0.049	1.521ArgThr: 1.521 ± 0.044	2.399ArgVal: 2.399 ± 0.059	0.266ArgTrp: 0.266 ± 0.023	1.546ArgTyr: 1.546 ± 0.047	0.0ArgXaa: 0.0 ± 0.0
Ser	2.695SerAla: 2.695 ± 0.061	0.571SerCys: 0.571 ± 0.028	2.778SerAsp: 2.778 ± 0.068	3.741SerGlu: 3.741 ± 0.081	2.729SerPhe: 2.729 ± 0.068	3.639SerGly: 3.639 ± 0.084	0.84SerHis: 0.84 ± 0.035	6.451SerIle: 6.451 ± 0.121	5.707SerLys: 5.707 ± 0.104	5.206SerLeu: 5.206 ± 0.089	1.475SerMet: 1.475 ± 0.05	3.194SerAsn: 3.194 ± 0.075	1.551SerPro: 1.551 ± 0.047	1.313SerGln: 1.313 ± 0.046	2.094SerArg: 2.094 ± 0.057	3.489SerSer: 3.489 ± 0.086	2.516SerThr: 2.516 ± 0.058	3.278SerVal: 3.278 ± 0.071	0.381SerTrp: 0.381 ± 0.024	2.092SerTyr: 2.092 ± 0.059	0.0SerXaa: 0.0 ± 0.0
Thr	2.889ThrAla: 2.889 ± 0.077	0.446ThrCys: 0.446 ± 0.024	2.326ThrAsp: 2.326 ± 0.057	2.731ThrGlu: 2.731 ± 0.069	1.909ThrPhe: 1.909 ± 0.051	3.519ThrGly: 3.519 ± 0.077	0.714ThrHis: 0.714 ± 0.025	4.609ThrIle: 4.609 ± 0.092	3.582ThrLys: 3.582 ± 0.075	4.144ThrLeu: 4.144 ± 0.08	0.972ThrMet: 0.972 ± 0.039	2.316ThrAsn: 2.316 ± 0.057	1.767ThrPro: 1.767 ± 0.05	0.974ThrGln: 0.974 ± 0.036	1.593ThrArg: 1.593 ± 0.051	2.67ThrSer: 2.67 ± 0.06	2.184ThrThr: 2.184 ± 0.059	3.184ThrVal: 3.184 ± 0.072	0.269ThrTrp: 0.269 ± 0.019	1.695ThrTyr: 1.695 ± 0.055	0.0ThrXaa: 0.0 ± 0.0
Val	3.706ValAla: 3.706 ± 0.083	0.692ValCys: 0.692 ± 0.033	3.821ValAsp: 3.821 ± 0.067	4.826ValGlu: 4.826 ± 0.084	2.807ValPhe: 2.807 ± 0.078	4.258ValGly: 4.258 ± 0.089	0.882ValHis: 0.882 ± 0.038	6.653ValIle: 6.653 ± 0.109	6.361ValLys: 6.361 ± 0.112	5.964ValLeu: 5.964 ± 0.095	1.455ValMet: 1.455 ± 0.043	3.514ValAsn: 3.514 ± 0.076	2.155ValPro: 2.155 ± 0.064	1.295ValGln: 1.295 ± 0.041	2.222ValArg: 2.222 ± 0.059	3.805ValSer: 3.805 ± 0.075	2.821ValThr: 2.821 ± 0.07	4.811ValVal: 4.811 ± 0.099	0.383ValTrp: 0.383 ± 0.021	2.463ValTyr: 2.463 ± 0.059	0.0ValXaa: 0.0 ± 0.0
Trp	0.381TrpAla: 0.381 ± 0.024	0.057TrpCys: 0.057 ± 0.009	0.338TrpAsp: 0.338 ± 0.024	0.406TrpGlu: 0.406 ± 0.026	0.301TrpPhe: 0.301 ± 0.021	0.473TrpGly: 0.473 ± 0.032	0.129TrpHis: 0.129 ± 0.015	0.645TrpIle: 0.645 ± 0.031	0.532TrpLys: 0.532 ± 0.031	0.56TrpLeu: 0.56 ± 0.032	0.169TrpMet: 0.169 ± 0.016	0.417TrpAsn: 0.417 ± 0.024	0.137TrpPro: 0.137 ± 0.014	0.176TrpGln: 0.176 ± 0.015	0.231TrpArg: 0.231 ± 0.019	0.297TrpSer: 0.297 ± 0.025	0.27TrpThr: 0.27 ± 0.02	0.342TrpVal: 0.342 ± 0.022	0.067TrpTrp: 0.067 ± 0.01	0.268TrpTyr: 0.268 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.792TyrAla: 1.792 ± 0.053	0.463TyrCys: 0.463 ± 0.028	2.496TyrAsp: 2.496 ± 0.062	2.934TyrGlu: 2.934 ± 0.066	2.01TyrPhe: 2.01 ± 0.056	2.549TyrGly: 2.549 ± 0.063	0.602TyrHis: 0.602 ± 0.032	4.415TyrIle: 4.415 ± 0.067	4.036TyrLys: 4.036 ± 0.089	3.576TyrLeu: 3.576 ± 0.078	0.926TyrMet: 0.926 ± 0.037	2.445TyrAsn: 2.445 ± 0.059	1.338TyrPro: 1.338 ± 0.052	0.754TyrGln: 0.754 ± 0.031	1.679TyrArg: 1.679 ± 0.056	2.329TyrSer: 2.329 ± 0.062	1.819TyrThr: 1.819 ± 0.048	2.187TyrVal: 2.187 ± 0.059	0.266TyrTrp: 0.266 ± 0.021	1.832TyrTyr: 1.832 ± 0.055	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2351 proteins (721450 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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