Amino acid dipepetide frequency for Grapevine geminivirus A

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.662AlaAla: 2.662 ± 1.215
1.775AlaCys: 1.775 ± 1.356
3.549AlaAsp: 3.549 ± 2.645
2.662AlaGlu: 2.662 ± 1.399
1.775AlaPhe: 1.775 ± 1.212
1.775AlaGly: 1.775 ± 0.713
1.775AlaHis: 1.775 ± 0.713
0.887AlaIle: 0.887 ± 0.606
5.324AlaLys: 5.324 ± 1.851
8.873AlaLeu: 8.873 ± 3.721
0.0AlaMet: 0.0 ± 0.0
3.549AlaAsn: 3.549 ± 1.308
2.662AlaPro: 2.662 ± 1.045
5.324AlaGln: 5.324 ± 2.066
2.662AlaArg: 2.662 ± 0.903
1.775AlaSer: 1.775 ± 0.713
2.662AlaThr: 2.662 ± 0.903
0.0AlaVal: 0.0 ± 0.0
0.0AlaTrp: 0.0 ± 0.0
0.887AlaTyr: 0.887 ± 0.606
0.0AlaXaa: 0.0 ± 0.0
Cys
0.887CysAla: 0.887 ± 0.812
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.887CysGlu: 0.887 ± 1.019
0.887CysPhe: 0.887 ± 1.238
0.0CysGly: 0.0 ± 0.0
0.887CysHis: 0.887 ± 0.606
0.887CysIle: 0.887 ± 1.09
0.887CysLys: 0.887 ± 0.812
0.0CysLeu: 0.0 ± 0.0
0.887CysMet: 0.887 ± 1.238
3.549CysAsn: 3.549 ± 2.367
0.0CysPro: 0.0 ± 0.0
1.775CysGln: 1.775 ± 2.18
2.662CysArg: 2.662 ± 2.198
0.887CysSer: 0.887 ± 1.019
0.887CysThr: 0.887 ± 0.812
0.0CysVal: 0.0 ± 0.0
0.887CysTrp: 0.887 ± 0.812
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.549AspAla: 3.549 ± 1.188
0.0AspCys: 0.0 ± 0.0
2.662AspAsp: 2.662 ± 0.903
3.549AspGlu: 3.549 ± 1.188
1.775AspPhe: 1.775 ± 1.248
3.549AspGly: 3.549 ± 2.424
2.662AspHis: 2.662 ± 1.696
1.775AspIle: 1.775 ± 1.028
2.662AspLys: 2.662 ± 1.05
5.324AspLeu: 5.324 ± 1.562
0.0AspMet: 0.0 ± 0.0
0.887AspAsn: 0.887 ± 1.09
0.887AspPro: 0.887 ± 0.606
2.662AspGln: 2.662 ± 1.189
3.549AspArg: 3.549 ± 1.379
6.211AspSer: 6.211 ± 1.401
1.775AspThr: 1.775 ± 0.982
3.549AspVal: 3.549 ± 1.805
2.662AspTrp: 2.662 ± 1.05
1.775AspTyr: 1.775 ± 1.212
0.0AspXaa: 0.0 ± 0.0
Glu
0.887GluAla: 0.887 ± 0.606
0.0GluCys: 0.0 ± 0.0
2.662GluAsp: 2.662 ± 1.402
5.324GluGlu: 5.324 ± 2.688
3.549GluPhe: 3.549 ± 1.805
6.211GluGly: 6.211 ± 2.822
0.0GluHis: 0.0 ± 0.0
1.775GluIle: 1.775 ± 2.039
6.211GluLys: 6.211 ± 3.454
5.324GluLeu: 5.324 ± 1.804
1.775GluMet: 1.775 ± 1.535
2.662GluAsn: 2.662 ± 1.565
0.887GluPro: 0.887 ± 0.606
0.887GluGln: 0.887 ± 0.606
0.887GluArg: 0.887 ± 1.019
5.324GluSer: 5.324 ± 2.136
0.887GluThr: 0.887 ± 0.812
0.887GluVal: 0.887 ± 1.238
0.0GluTrp: 0.0 ± 0.0
0.887GluTyr: 0.887 ± 0.606
0.0GluXaa: 0.0 ± 0.0
Phe
0.887PheAla: 0.887 ± 0.812
0.0PheCys: 0.0 ± 0.0
1.775PheAsp: 1.775 ± 0.89
1.775PheGlu: 1.775 ± 1.377
0.887PhePhe: 0.887 ± 0.606
3.549PheGly: 3.549 ± 1.604
1.775PheHis: 1.775 ± 1.212
2.662PheIle: 2.662 ± 1.402
4.437PheLys: 4.437 ± 2.365
3.549PheLeu: 3.549 ± 1.805
2.662PheMet: 2.662 ± 1.283
3.549PheAsn: 3.549 ± 1.044
0.887PhePro: 0.887 ± 0.606
4.437PheGln: 4.437 ± 1.477
5.324PheArg: 5.324 ± 2.197
2.662PheSer: 2.662 ± 1.215
5.324PheThr: 5.324 ± 1.806
0.887PheVal: 0.887 ± 0.606
0.0PheTrp: 0.0 ± 0.0
1.775PheTyr: 1.775 ± 1.623
0.0PheXaa: 0.0 ± 0.0
Gly
5.324GlyAla: 5.324 ± 1.851
0.0GlyCys: 0.0 ± 0.0
2.662GlyAsp: 2.662 ± 1.045
3.549GlyGlu: 3.549 ± 1.044
4.437GlyPhe: 4.437 ± 1.956
7.098GlyGly: 7.098 ± 3.521
2.662GlyHis: 2.662 ± 1.198
2.662GlyIle: 2.662 ± 1.198
6.211GlyLys: 6.211 ± 2.544
6.211GlyLeu: 6.211 ± 1.479
0.0GlyMet: 0.0 ± 0.0
2.662GlyAsn: 2.662 ± 2.456
3.549GlyPro: 3.549 ± 2.127
2.662GlyGln: 2.662 ± 1.05
4.437GlyArg: 4.437 ± 1.683
4.437GlySer: 4.437 ± 2.973
0.887GlyThr: 0.887 ± 1.019
4.437GlyVal: 4.437 ± 2.509
0.887GlyTrp: 0.887 ± 0.606
0.887GlyTyr: 0.887 ± 0.812
0.0GlyXaa: 0.0 ± 0.0
His
0.887HisAla: 0.887 ± 0.606
0.887HisCys: 0.887 ± 1.238
0.887HisAsp: 0.887 ± 0.812
0.887HisGlu: 0.887 ± 1.09
1.775HisPhe: 1.775 ± 1.212
0.887HisGly: 0.887 ± 1.019
0.887HisHis: 0.887 ± 0.606
2.662HisIle: 2.662 ± 1.565
1.775HisLys: 1.775 ± 1.377
5.324HisLeu: 5.324 ± 1.47
0.887HisMet: 0.887 ± 0.757
3.549HisAsn: 3.549 ± 1.013
1.775HisPro: 1.775 ± 1.064
0.887HisGln: 0.887 ± 0.606
1.775HisArg: 1.775 ± 1.248
0.887HisSer: 0.887 ± 0.812
1.775HisThr: 1.775 ± 1.248
4.437HisVal: 4.437 ± 1.543
0.887HisTrp: 0.887 ± 0.812
2.662HisTyr: 2.662 ± 1.818
0.0HisXaa: 0.0 ± 0.0
Ile
1.775IleAla: 1.775 ± 0.982
1.775IleCys: 1.775 ± 1.535
2.662IleAsp: 2.662 ± 1.399
1.775IleGlu: 1.775 ± 1.212
5.324IlePhe: 5.324 ± 2.371
0.0IleGly: 0.0 ± 0.0
1.775IleHis: 1.775 ± 1.064
3.549IleIle: 3.549 ± 1.013
2.662IleLys: 2.662 ± 1.402
6.211IleLeu: 6.211 ± 1.598
0.0IleMet: 0.0 ± 0.0
2.662IleAsn: 2.662 ± 1.768
1.775IlePro: 1.775 ± 0.982
5.324IleGln: 5.324 ± 2.644
2.662IleArg: 2.662 ± 1.666
9.76IleSer: 9.76 ± 2.489
0.887IleThr: 0.887 ± 0.812
0.0IleVal: 0.0 ± 0.0
0.887IleTrp: 0.887 ± 1.09
3.549IleTyr: 3.549 ± 1.408
0.0IleXaa: 0.0 ± 0.0
Lys
3.549LysAla: 3.549 ± 1.009
0.887LysCys: 0.887 ± 0.812
2.662LysAsp: 2.662 ± 1.818
5.324LysGlu: 5.324 ± 2.974
1.775LysPhe: 1.775 ± 0.89
4.437LysGly: 4.437 ± 1.711
2.662LysHis: 2.662 ± 1.045
2.662LysIle: 2.662 ± 1.415
0.0LysLys: 0.0 ± 0.0
2.662LysLeu: 2.662 ± 2.435
0.0LysMet: 0.0 ± 0.0
4.437LysAsn: 4.437 ± 2.365
2.662LysPro: 2.662 ± 1.818
0.887LysGln: 0.887 ± 1.09
2.662LysArg: 2.662 ± 1.826
7.098LysSer: 7.098 ± 0.849
5.324LysThr: 5.324 ± 2.011
3.549LysVal: 3.549 ± 1.188
0.0LysTrp: 0.0 ± 0.0
2.662LysTyr: 2.662 ± 1.402
0.0LysXaa: 0.0 ± 0.0
Leu
1.775LeuAla: 1.775 ± 1.028
0.887LeuCys: 0.887 ± 0.606
7.986LeuAsp: 7.986 ± 2.565
4.437LeuGlu: 4.437 ± 1.291
3.549LeuPhe: 3.549 ± 1.408
6.211LeuGly: 6.211 ± 1.528
5.324LeuHis: 5.324 ± 0.896
2.662LeuIle: 2.662 ± 1.283
7.986LeuLys: 7.986 ± 2.978
0.887LeuLeu: 0.887 ± 0.606
2.662LeuMet: 2.662 ± 1.696
4.437LeuAsn: 4.437 ± 1.689
1.775LeuPro: 1.775 ± 1.338
4.437LeuGln: 4.437 ± 1.888
2.662LeuArg: 2.662 ± 1.593
4.437LeuSer: 4.437 ± 2.029
7.098LeuThr: 7.098 ± 1.716
6.211LeuVal: 6.211 ± 1.074
2.662LeuTrp: 2.662 ± 1.045
4.437LeuTyr: 4.437 ± 2.637
0.0LeuXaa: 0.0 ± 0.0
Met
0.887MetAla: 0.887 ± 0.606
0.0MetCys: 0.0 ± 0.0
2.662MetAsp: 2.662 ± 1.427
0.887MetGlu: 0.887 ± 1.019
0.0MetPhe: 0.0 ± 0.0
1.775MetGly: 1.775 ± 1.291
0.887MetHis: 0.887 ± 1.238
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
2.662MetLeu: 2.662 ± 1.768
0.0MetMet: 0.0 ± 0.0
1.775MetAsn: 1.775 ± 1.623
3.549MetPro: 3.549 ± 1.009
0.887MetGln: 0.887 ± 1.09
0.887MetArg: 0.887 ± 0.812
1.775MetSer: 1.775 ± 1.34
0.887MetThr: 0.887 ± 0.812
0.0MetVal: 0.0 ± 0.0
0.887MetTrp: 0.887 ± 1.019
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.549AsnAla: 3.549 ± 2.424
3.549AsnCys: 3.549 ± 2.495
4.437AsnAsp: 4.437 ± 1.291
0.887AsnGlu: 0.887 ± 0.812
1.775AsnPhe: 1.775 ± 1.34
0.0AsnGly: 0.0 ± 0.0
2.662AsnHis: 2.662 ± 2.347
4.437AsnIle: 4.437 ± 2.124
0.0AsnLys: 0.0 ± 0.0
1.775AsnLeu: 1.775 ± 0.89
2.662AsnMet: 2.662 ± 1.154
0.887AsnAsn: 0.887 ± 0.606
6.211AsnPro: 6.211 ± 1.992
0.887AsnGln: 0.887 ± 0.606
2.662AsnArg: 2.662 ± 2.449
3.549AsnSer: 3.549 ± 2.583
1.775AsnThr: 1.775 ± 0.713
1.775AsnVal: 1.775 ± 0.713
0.887AsnTrp: 0.887 ± 0.606
0.887AsnTyr: 0.887 ± 0.606
0.0AsnXaa: 0.0 ± 0.0
Pro
3.549ProAla: 3.549 ± 1.01
1.775ProCys: 1.775 ± 2.18
2.662ProAsp: 2.662 ± 0.903
1.775ProGlu: 1.775 ± 1.623
1.775ProPhe: 1.775 ± 1.212
2.662ProGly: 2.662 ± 1.189
3.549ProHis: 3.549 ± 1.188
3.549ProIle: 3.549 ± 2.035
3.549ProLys: 3.549 ± 1.805
4.437ProLeu: 4.437 ± 1.45
0.0ProMet: 0.0 ± 0.0
1.775ProAsn: 1.775 ± 1.212
2.662ProPro: 2.662 ± 1.818
5.324ProGln: 5.324 ± 1.175
4.437ProArg: 4.437 ± 1.367
7.098ProSer: 7.098 ± 1.703
2.662ProThr: 2.662 ± 1.565
1.775ProVal: 1.775 ± 0.89
0.0ProTrp: 0.0 ± 0.0
0.887ProTyr: 0.887 ± 0.812
0.0ProXaa: 0.0 ± 0.0
Gln
2.662GlnAla: 2.662 ± 1.565
1.775GlnCys: 1.775 ± 0.982
3.549GlnAsp: 3.549 ± 1.255
1.775GlnGlu: 1.775 ± 1.064
2.662GlnPhe: 2.662 ± 1.198
4.437GlnGly: 4.437 ± 2.092
2.662GlnHis: 2.662 ± 1.696
4.437GlnIle: 4.437 ± 1.098
0.887GlnLys: 0.887 ± 1.09
4.437GlnLeu: 4.437 ± 2.235
0.887GlnMet: 0.887 ± 1.09
0.0GlnAsn: 0.0 ± 0.0
0.887GlnPro: 0.887 ± 0.606
1.775GlnGln: 1.775 ± 1.338
3.549GlnArg: 3.549 ± 1.408
7.098GlnSer: 7.098 ± 1.404
4.437GlnThr: 4.437 ± 1.806
2.662GlnVal: 2.662 ± 1.05
0.887GlnTrp: 0.887 ± 1.019
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.549ArgAla: 3.549 ± 1.009
0.0ArgCys: 0.0 ± 0.0
0.887ArgAsp: 0.887 ± 0.812
2.662ArgGlu: 2.662 ± 1.565
1.775ArgPhe: 1.775 ± 0.713
6.211ArgGly: 6.211 ± 1.211
0.887ArgHis: 0.887 ± 0.812
5.324ArgIle: 5.324 ± 1.635
3.549ArgLys: 3.549 ± 1.367
4.437ArgLeu: 4.437 ± 2.062
0.887ArgMet: 0.887 ± 1.093
1.775ArgAsn: 1.775 ± 1.623
5.324ArgPro: 5.324 ± 1.58
2.662ArgGln: 2.662 ± 1.189
9.76ArgArg: 9.76 ± 6.013
5.324ArgSer: 5.324 ± 1.985
4.437ArgThr: 4.437 ± 1.249
2.662ArgVal: 2.662 ± 1.666
0.887ArgTrp: 0.887 ± 0.812
0.0ArgTyr: 0.0 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
4.437SerAla: 4.437 ± 2.112
0.887SerCys: 0.887 ± 0.812
2.662SerAsp: 2.662 ± 1.402
4.437SerGlu: 4.437 ± 1.951
5.324SerPhe: 5.324 ± 0.896
4.437SerGly: 4.437 ± 2.112
0.887SerHis: 0.887 ± 0.606
4.437SerIle: 4.437 ± 1.376
2.662SerLys: 2.662 ± 0.903
7.986SerLeu: 7.986 ± 1.963
4.437SerMet: 4.437 ± 2.254
1.775SerAsn: 1.775 ± 0.982
7.098SerPro: 7.098 ± 3.717
5.324SerGln: 5.324 ± 2.091
7.098SerArg: 7.098 ± 3.341
17.746SerSer: 17.746 ± 2.628
4.437SerThr: 4.437 ± 2.138
6.211SerVal: 6.211 ± 2.951
3.549SerTrp: 3.549 ± 2.367
4.437SerTyr: 4.437 ± 1.303
0.0SerXaa: 0.0 ± 0.0
Thr
3.549ThrAla: 3.549 ± 1.677
0.887ThrCys: 0.887 ± 0.812
2.662ThrAsp: 2.662 ± 1.624
1.775ThrGlu: 1.775 ± 1.704
3.549ThrPhe: 3.549 ± 1.74
4.437ThrGly: 4.437 ± 1.758
0.887ThrHis: 0.887 ± 1.09
1.775ThrIle: 1.775 ± 1.028
2.662ThrLys: 2.662 ± 1.402
6.211ThrLeu: 6.211 ± 3.027
1.775ThrMet: 1.775 ± 0.713
2.662ThrAsn: 2.662 ± 0.903
6.211ThrPro: 6.211 ± 2.576
2.662ThrGln: 2.662 ± 1.624
0.0ThrArg: 0.0 ± 0.0
4.437ThrSer: 4.437 ± 1.098
3.549ThrThr: 3.549 ± 1.044
0.887ThrVal: 0.887 ± 1.09
0.887ThrTrp: 0.887 ± 1.238
5.324ThrTyr: 5.324 ± 2.039
0.0ThrXaa: 0.0 ± 0.0
Val
0.887ValAla: 0.887 ± 0.812
1.775ValCys: 1.775 ± 1.704
1.775ValAsp: 1.775 ± 1.064
0.887ValGlu: 0.887 ± 0.606
3.549ValPhe: 3.549 ± 1.188
5.324ValGly: 5.324 ± 1.884
0.0ValHis: 0.0 ± 0.0
2.662ValIle: 2.662 ± 0.819
2.662ValLys: 2.662 ± 1.283
3.549ValLeu: 3.549 ± 1.367
0.0ValMet: 0.0 ± 0.0
0.887ValAsn: 0.887 ± 0.812
2.662ValPro: 2.662 ± 0.903
1.775ValGln: 1.775 ± 0.982
2.662ValArg: 2.662 ± 1.665
4.437ValSer: 4.437 ± 1.566
3.549ValThr: 3.549 ± 1.604
0.0ValVal: 0.0 ± 0.0
2.662ValTrp: 2.662 ± 0.819
1.775ValTyr: 1.775 ± 1.028
0.0ValXaa: 0.0 ± 0.0
Trp
3.549TrpAla: 3.549 ± 0.899
0.0TrpCys: 0.0 ± 0.0
1.775TrpAsp: 1.775 ± 0.89
1.775TrpGlu: 1.775 ± 0.713
0.0TrpPhe: 0.0 ± 0.0
0.887TrpGly: 0.887 ± 0.606
0.0TrpHis: 0.0 ± 0.0
3.549TrpIle: 3.549 ± 2.675
0.0TrpLys: 0.0 ± 0.0
0.887TrpLeu: 0.887 ± 1.019
0.0TrpMet: 0.0 ± 0.0
0.887TrpAsn: 0.887 ± 0.812
0.0TrpPro: 0.0 ± 0.0
0.887TrpGln: 0.887 ± 0.606
0.887TrpArg: 0.887 ± 0.812
0.887TrpSer: 0.887 ± 0.812
1.775TrpThr: 1.775 ± 1.625
0.887TrpVal: 0.887 ± 0.606
0.0TrpTrp: 0.0 ± 0.0
0.887TrpTyr: 0.887 ± 1.238
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.775TyrAla: 1.775 ± 0.982
0.0TyrCys: 0.0 ± 0.0
0.887TyrAsp: 0.887 ± 0.812
0.0TyrGlu: 0.0 ± 0.0
2.662TyrPhe: 2.662 ± 0.819
1.775TyrGly: 1.775 ± 0.713
3.549TyrHis: 3.549 ± 2.178
2.662TyrIle: 2.662 ± 1.215
1.775TyrLys: 1.775 ± 0.713
1.775TyrLeu: 1.775 ± 1.212
0.0TyrMet: 0.0 ± 0.752
0.887TyrAsn: 0.887 ± 0.606
4.437TyrPro: 4.437 ± 1.52
0.0TyrGln: 0.0 ± 0.0
1.775TyrArg: 1.775 ± 1.028
4.437TyrSer: 4.437 ± 2.26
1.775TyrThr: 1.775 ± 0.713
2.662TyrVal: 2.662 ± 1.665
0.0TyrTrp: 0.0 ± 0.0
0.887TyrTyr: 0.887 ± 0.812
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1128 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski