Amino acid dipepetide frequency for Lake Sarah-associated circular virus-45

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.658AlaAla: 11.658 ± 0.778
2.591AlaCys: 2.591 ± 2.432
0.0AlaAsp: 0.0 ± 0.0
5.181AlaGlu: 5.181 ± 2.91
2.591AlaPhe: 2.591 ± 2.432
10.363AlaGly: 10.363 ± 1.913
1.295AlaHis: 1.295 ± 0.738
7.772AlaIle: 7.772 ± 3.388
3.886AlaLys: 3.886 ± 0.259
6.477AlaLeu: 6.477 ± 0.219
3.886AlaMet: 3.886 ± 2.213
3.886AlaAsn: 3.886 ± 2.213
2.591AlaPro: 2.591 ± 2.432
3.886AlaGln: 3.886 ± 2.213
3.886AlaArg: 3.886 ± 2.213
6.477AlaSer: 6.477 ± 3.688
5.181AlaThr: 5.181 ± 0.997
2.591AlaVal: 2.591 ± 1.475
1.295AlaTrp: 1.295 ± 0.738
1.295AlaTyr: 1.295 ± 0.738
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
2.591CysGlu: 2.591 ± 0.478
1.295CysPhe: 1.295 ± 0.738
1.295CysGly: 1.295 ± 1.216
0.0CysHis: 0.0 ± 0.0
2.591CysIle: 2.591 ± 2.432
1.295CysLys: 1.295 ± 1.216
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
2.591CysAsn: 2.591 ± 0.478
1.295CysPro: 1.295 ± 0.738
2.591CysGln: 2.591 ± 0.478
1.295CysArg: 1.295 ± 1.216
2.591CysSer: 2.591 ± 1.475
1.295CysThr: 1.295 ± 1.216
1.295CysVal: 1.295 ± 0.738
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.181AspAla: 5.181 ± 0.997
1.295AspCys: 1.295 ± 0.738
2.591AspAsp: 2.591 ± 2.432
0.0AspGlu: 0.0 ± 0.0
2.591AspPhe: 2.591 ± 2.432
2.591AspGly: 2.591 ± 2.432
0.0AspHis: 0.0 ± 0.0
2.591AspIle: 2.591 ± 0.478
1.295AspLys: 1.295 ± 1.216
6.477AspLeu: 6.477 ± 1.734
0.0AspMet: 0.0 ± 0.0
2.591AspAsn: 2.591 ± 1.475
3.886AspPro: 3.886 ± 1.694
1.295AspGln: 1.295 ± 1.216
1.295AspArg: 1.295 ± 0.738
3.886AspSer: 3.886 ± 0.259
1.295AspThr: 1.295 ± 1.216
3.886AspVal: 3.886 ± 0.259
2.591AspTrp: 2.591 ± 2.432
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
2.591GluAla: 2.591 ± 2.432
1.295GluCys: 1.295 ± 0.738
3.886GluAsp: 3.886 ± 1.694
3.886GluGlu: 3.886 ± 0.259
0.0GluPhe: 0.0 ± 0.0
1.295GluGly: 1.295 ± 1.216
1.295GluHis: 1.295 ± 1.216
3.886GluIle: 3.886 ± 0.259
1.295GluLys: 1.295 ± 1.216
2.591GluLeu: 2.591 ± 0.478
0.0GluMet: 0.0 ± 0.0
2.591GluAsn: 2.591 ± 0.478
2.591GluPro: 2.591 ± 1.475
0.0GluGln: 0.0 ± 0.0
0.0GluArg: 0.0 ± 0.0
3.886GluSer: 3.886 ± 1.694
3.886GluThr: 3.886 ± 0.259
0.0GluVal: 0.0 ± 0.0
1.295GluTrp: 1.295 ± 1.216
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
3.886PheAla: 3.886 ± 2.213
0.0PheCys: 0.0 ± 0.0
6.477PheAsp: 6.477 ± 2.172
1.295PheGlu: 1.295 ± 1.216
2.591PhePhe: 2.591 ± 0.478
2.591PheGly: 2.591 ± 1.475
1.295PheHis: 1.295 ± 1.216
1.295PheIle: 1.295 ± 1.216
5.181PheLys: 5.181 ± 0.997
3.886PheLeu: 3.886 ± 1.694
0.0PheMet: 0.0 ± 0.0
3.886PheAsn: 3.886 ± 3.647
1.295PhePro: 1.295 ± 0.738
2.591PheGln: 2.591 ± 0.478
1.295PheArg: 1.295 ± 0.738
2.591PheSer: 2.591 ± 1.475
3.886PheThr: 3.886 ± 1.694
3.886PheVal: 3.886 ± 0.259
0.0PheTrp: 0.0 ± 0.0
1.295PheTyr: 1.295 ± 1.216
0.0PheXaa: 0.0 ± 0.0
Gly
3.886GlyAla: 3.886 ± 2.213
2.591GlyCys: 2.591 ± 0.478
1.295GlyAsp: 1.295 ± 0.738
1.295GlyGlu: 1.295 ± 1.216
2.591GlyPhe: 2.591 ± 0.478
3.886GlyGly: 3.886 ± 0.259
3.886GlyHis: 3.886 ± 0.259
5.181GlyIle: 5.181 ± 2.95
6.477GlyLys: 6.477 ± 0.219
6.477GlyLeu: 6.477 ± 1.734
0.0GlyMet: 0.0 ± 0.0
2.591GlyAsn: 2.591 ± 0.478
5.181GlyPro: 5.181 ± 0.997
2.591GlyGln: 2.591 ± 2.432
6.477GlyArg: 6.477 ± 3.688
1.295GlySer: 1.295 ± 0.738
10.363GlyThr: 10.363 ± 0.04
3.886GlyVal: 3.886 ± 0.259
0.0GlyTrp: 0.0 ± 0.0
3.886GlyTyr: 3.886 ± 1.694
0.0GlyXaa: 0.0 ± 0.0
His
2.591HisAla: 2.591 ± 2.432
1.295HisCys: 1.295 ± 0.738
1.295HisAsp: 1.295 ± 1.216
1.295HisGlu: 1.295 ± 1.216
1.295HisPhe: 1.295 ± 0.738
1.295HisGly: 1.295 ± 1.216
1.295HisHis: 1.295 ± 1.216
3.886HisIle: 3.886 ± 1.694
1.295HisLys: 1.295 ± 1.216
2.591HisLeu: 2.591 ± 0.478
0.0HisMet: 0.0 ± 0.0
1.295HisAsn: 1.295 ± 0.738
2.591HisPro: 2.591 ± 0.478
0.0HisGln: 0.0 ± 0.0
1.295HisArg: 1.295 ± 1.216
2.591HisSer: 2.591 ± 0.478
1.295HisThr: 1.295 ± 0.738
1.295HisVal: 1.295 ± 1.216
0.0HisTrp: 0.0 ± 0.0
1.295HisTyr: 1.295 ± 1.216
0.0HisXaa: 0.0 ± 0.0
Ile
1.295IleAla: 1.295 ± 1.216
0.0IleCys: 0.0 ± 0.0
2.591IleAsp: 2.591 ± 0.478
1.295IleGlu: 1.295 ± 1.216
3.886IlePhe: 3.886 ± 1.694
1.295IleGly: 1.295 ± 0.738
3.886IleHis: 3.886 ± 1.694
3.886IleIle: 3.886 ± 1.694
2.591IleLys: 2.591 ± 1.475
1.295IleLeu: 1.295 ± 0.738
1.295IleMet: 1.295 ± 0.738
5.181IleAsn: 5.181 ± 0.997
1.295IlePro: 1.295 ± 1.216
1.295IleGln: 1.295 ± 1.216
3.886IleArg: 3.886 ± 1.694
3.886IleSer: 3.886 ± 0.259
6.477IleThr: 6.477 ± 1.734
9.067IleVal: 9.067 ± 2.65
0.0IleTrp: 0.0 ± 0.0
2.591IleTyr: 2.591 ± 1.475
0.0IleXaa: 0.0 ± 0.0
Lys
2.591LysAla: 2.591 ± 0.478
0.0LysCys: 0.0 ± 0.0
1.295LysAsp: 1.295 ± 1.216
1.295LysGlu: 1.295 ± 0.738
3.886LysPhe: 3.886 ± 0.259
3.886LysGly: 3.886 ± 0.259
1.295LysHis: 1.295 ± 1.216
1.295LysIle: 1.295 ± 1.216
2.591LysLys: 2.591 ± 1.475
5.181LysLeu: 5.181 ± 2.95
0.0LysMet: 0.0 ± 0.0
0.0LysAsn: 0.0 ± 0.0
3.886LysPro: 3.886 ± 0.259
5.181LysGln: 5.181 ± 2.91
5.181LysArg: 5.181 ± 0.956
3.886LysSer: 3.886 ± 2.213
7.772LysThr: 7.772 ± 3.388
3.886LysVal: 3.886 ± 0.259
0.0LysTrp: 0.0 ± 0.0
2.591LysTyr: 2.591 ± 1.475
0.0LysXaa: 0.0 ± 0.0
Leu
5.181LeuAla: 5.181 ± 2.91
1.295LeuCys: 1.295 ± 0.738
1.295LeuAsp: 1.295 ± 1.216
2.591LeuGlu: 2.591 ± 1.475
6.477LeuPhe: 6.477 ± 1.734
0.0LeuGly: 0.0 ± 0.0
1.295LeuHis: 1.295 ± 1.216
1.295LeuIle: 1.295 ± 0.738
9.067LeuLys: 9.067 ± 1.256
6.477LeuLeu: 6.477 ± 1.734
1.295LeuMet: 1.295 ± 0.738
1.295LeuAsn: 1.295 ± 0.738
1.295LeuPro: 1.295 ± 0.738
1.295LeuGln: 1.295 ± 0.738
5.181LeuArg: 5.181 ± 0.997
2.591LeuSer: 2.591 ± 1.475
11.658LeuThr: 11.658 ± 3.129
3.886LeuVal: 3.886 ± 2.213
1.295LeuTrp: 1.295 ± 1.216
6.477LeuTyr: 6.477 ± 3.688
0.0LeuXaa: 0.0 ± 0.0
Met
1.295MetAla: 1.295 ± 0.738
1.295MetCys: 1.295 ± 1.216
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
1.295MetPhe: 1.295 ± 0.738
1.295MetGly: 1.295 ± 0.738
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.295MetLys: 1.295 ± 0.738
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
1.295MetAsn: 1.295 ± 0.738
2.591MetPro: 2.591 ± 0.478
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
2.591MetSer: 2.591 ± 1.475
1.295MetThr: 1.295 ± 0.738
0.0MetVal: 0.0 ± 0.0
1.295MetTrp: 1.295 ± 0.738
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
6.477AsnAla: 6.477 ± 3.688
1.295AsnCys: 1.295 ± 0.738
1.295AsnAsp: 1.295 ± 0.738
3.886AsnGlu: 3.886 ± 0.259
3.886AsnPhe: 3.886 ± 1.694
6.477AsnGly: 6.477 ± 0.219
1.295AsnHis: 1.295 ± 1.216
3.886AsnIle: 3.886 ± 2.213
2.591AsnLys: 2.591 ± 0.478
2.591AsnLeu: 2.591 ± 1.475
2.591AsnMet: 2.591 ± 0.481
0.0AsnAsn: 0.0 ± 0.0
2.591AsnPro: 2.591 ± 0.478
0.0AsnGln: 0.0 ± 0.0
5.181AsnArg: 5.181 ± 0.997
1.295AsnSer: 1.295 ± 1.216
6.477AsnThr: 6.477 ± 3.688
5.181AsnVal: 5.181 ± 0.997
0.0AsnTrp: 0.0 ± 0.0
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
2.591ProAla: 2.591 ± 2.432
0.0ProCys: 0.0 ± 0.0
2.591ProAsp: 2.591 ± 1.475
1.295ProGlu: 1.295 ± 1.216
1.295ProPhe: 1.295 ± 0.738
5.181ProGly: 5.181 ± 0.997
1.295ProHis: 1.295 ± 1.216
1.295ProIle: 1.295 ± 0.738
2.591ProLys: 2.591 ± 0.478
3.886ProLeu: 3.886 ± 0.259
1.295ProMet: 1.295 ± 0.738
3.886ProAsn: 3.886 ± 0.259
3.886ProPro: 3.886 ± 0.259
1.295ProGln: 1.295 ± 1.216
9.067ProArg: 9.067 ± 0.697
6.477ProSer: 6.477 ± 0.219
1.295ProThr: 1.295 ± 0.738
0.0ProVal: 0.0 ± 0.0
0.0ProTrp: 0.0 ± 0.0
1.295ProTyr: 1.295 ± 0.738
0.0ProXaa: 0.0 ± 0.0
Gln
1.295GlnAla: 1.295 ± 0.738
1.295GlnCys: 1.295 ± 1.216
1.295GlnAsp: 1.295 ± 1.216
1.295GlnGlu: 1.295 ± 0.738
3.886GlnPhe: 3.886 ± 0.259
1.295GlnGly: 1.295 ± 0.738
2.591GlnHis: 2.591 ± 2.432
3.886GlnIle: 3.886 ± 0.259
0.0GlnLys: 0.0 ± 0.0
0.0GlnLeu: 0.0 ± 0.0
1.295GlnMet: 1.295 ± 1.216
5.181GlnAsn: 5.181 ± 2.95
3.886GlnPro: 3.886 ± 0.259
0.0GlnGln: 0.0 ± 0.0
0.0GlnArg: 0.0 ± 0.0
0.0GlnSer: 0.0 ± 0.0
0.0GlnThr: 0.0 ± 0.0
1.295GlnVal: 1.295 ± 0.738
0.0GlnTrp: 0.0 ± 0.0
2.591GlnTyr: 2.591 ± 2.432
0.0GlnXaa: 0.0 ± 0.0
Arg
9.067ArgAla: 9.067 ± 1.256
0.0ArgCys: 0.0 ± 0.0
2.591ArgAsp: 2.591 ± 0.478
1.295ArgGlu: 1.295 ± 1.216
2.591ArgPhe: 2.591 ± 0.478
9.067ArgGly: 9.067 ± 3.21
1.295ArgHis: 1.295 ± 0.738
5.181ArgIle: 5.181 ± 0.997
5.181ArgLys: 5.181 ± 0.956
1.295ArgLeu: 1.295 ± 1.216
0.0ArgMet: 0.0 ± 0.0
2.591ArgAsn: 2.591 ± 1.475
0.0ArgPro: 0.0 ± 0.0
0.0ArgGln: 0.0 ± 0.0
7.772ArgArg: 7.772 ± 0.519
5.181ArgSer: 5.181 ± 2.95
2.591ArgThr: 2.591 ± 0.478
3.886ArgVal: 3.886 ± 1.694
0.0ArgTrp: 0.0 ± 0.0
2.591ArgTyr: 2.591 ± 0.478
0.0ArgXaa: 0.0 ± 0.0
Ser
9.067SerAla: 9.067 ± 3.21
0.0SerCys: 0.0 ± 0.0
6.477SerAsp: 6.477 ± 1.734
1.295SerGlu: 1.295 ± 0.738
1.295SerPhe: 1.295 ± 1.216
10.363SerGly: 10.363 ± 3.947
1.295SerHis: 1.295 ± 1.216
0.0SerIle: 0.0 ± 0.0
2.591SerLys: 2.591 ± 0.478
9.067SerLeu: 9.067 ± 1.256
2.591SerMet: 2.591 ± 1.475
1.295SerAsn: 1.295 ± 0.738
1.295SerPro: 1.295 ± 0.738
0.0SerGln: 0.0 ± 0.0
3.886SerArg: 3.886 ± 2.213
5.181SerSer: 5.181 ± 2.95
3.886SerThr: 3.886 ± 0.259
5.181SerVal: 5.181 ± 0.997
0.0SerTrp: 0.0 ± 0.0
1.295SerTyr: 1.295 ± 0.738
0.0SerXaa: 0.0 ± 0.0
Thr
2.591ThrAla: 2.591 ± 1.475
5.181ThrCys: 5.181 ± 0.956
2.591ThrAsp: 2.591 ± 2.432
0.0ThrGlu: 0.0 ± 0.0
6.477ThrPhe: 6.477 ± 0.219
3.886ThrGly: 3.886 ± 0.259
2.591ThrHis: 2.591 ± 2.432
2.591ThrIle: 2.591 ± 2.432
2.591ThrLys: 2.591 ± 1.475
6.477ThrLeu: 6.477 ± 0.219
0.0ThrMet: 0.0 ± 0.591
3.886ThrAsn: 3.886 ± 2.213
6.477ThrPro: 6.477 ± 1.734
2.591ThrGln: 2.591 ± 1.475
1.295ThrArg: 1.295 ± 1.216
6.477ThrSer: 6.477 ± 1.734
6.477ThrThr: 6.477 ± 1.734
9.067ThrVal: 9.067 ± 1.256
1.295ThrTrp: 1.295 ± 1.216
2.591ThrTyr: 2.591 ± 2.432
0.0ThrXaa: 0.0 ± 0.0
Val
10.363ValAla: 10.363 ± 0.04
0.0ValCys: 0.0 ± 0.0
3.886ValAsp: 3.886 ± 1.694
3.886ValGlu: 3.886 ± 1.694
0.0ValPhe: 0.0 ± 0.0
3.886ValGly: 3.886 ± 2.213
2.591ValHis: 2.591 ± 1.475
3.886ValIle: 3.886 ± 0.259
3.886ValLys: 3.886 ± 1.694
5.181ValLeu: 5.181 ± 0.997
0.0ValMet: 0.0 ± 0.0
6.477ValAsn: 6.477 ± 0.219
1.295ValPro: 1.295 ± 0.738
1.295ValGln: 1.295 ± 0.738
2.591ValArg: 2.591 ± 2.432
5.181ValSer: 5.181 ± 0.997
1.295ValThr: 1.295 ± 0.738
3.886ValVal: 3.886 ± 1.694
1.295ValTrp: 1.295 ± 0.738
3.886ValTyr: 3.886 ± 2.213
0.0ValXaa: 0.0 ± 0.0
Trp
1.295TrpAla: 1.295 ± 1.216
1.295TrpCys: 1.295 ± 1.216
0.0TrpAsp: 0.0 ± 0.0
1.295TrpGlu: 1.295 ± 1.216
1.295TrpPhe: 1.295 ± 1.216
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
2.591TrpAsn: 2.591 ± 0.478
0.0TrpPro: 0.0 ± 0.0
1.295TrpGln: 1.295 ± 0.738
1.295TrpArg: 1.295 ± 0.738
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
1.295TrpTrp: 1.295 ± 0.738
1.295TrpTyr: 1.295 ± 1.216
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.886TyrAla: 3.886 ± 1.694
1.295TyrCys: 1.295 ± 1.216
3.886TyrAsp: 3.886 ± 2.213
1.295TyrGlu: 1.295 ± 0.738
0.0TyrPhe: 0.0 ± 0.0
3.886TyrGly: 3.886 ± 0.259
1.295TyrHis: 1.295 ± 0.738
2.591TyrIle: 2.591 ± 0.478
0.0TyrLys: 0.0 ± 0.0
1.295TyrLeu: 1.295 ± 0.738
0.0TyrMet: 0.0 ± 0.0
3.886TyrAsn: 3.886 ± 0.259
2.591TyrPro: 2.591 ± 2.432
3.886TyrGln: 3.886 ± 2.213
1.295TyrArg: 1.295 ± 0.738
0.0TyrSer: 0.0 ± 0.0
0.0TyrThr: 0.0 ± 0.0
2.591TyrVal: 2.591 ± 0.478
1.295TyrTrp: 1.295 ± 1.216
2.591TyrTyr: 2.591 ± 0.478
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (773 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski