Amino acid dipepetide frequency for Beihai picorna-like virus 69

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.388AlaAla: 0.388 ± 0.0
0.775AlaCys: 0.775 ± 0.0
2.326AlaAsp: 2.326 ± 0.0
2.714AlaGlu: 2.714 ± 0.0
2.326AlaPhe: 2.326 ± 0.0
5.816AlaGly: 5.816 ± 0.0
2.326AlaHis: 2.326 ± 0.0
3.49AlaIle: 3.49 ± 0.0
1.939AlaLys: 1.939 ± 0.0
1.939AlaLeu: 1.939 ± 0.0
0.388AlaMet: 0.388 ± 0.0
3.102AlaAsn: 3.102 ± 0.0
1.939AlaPro: 1.939 ± 0.0
1.163AlaGln: 1.163 ± 0.0
1.163AlaArg: 1.163 ± 0.0
3.877AlaSer: 3.877 ± 0.0
3.49AlaThr: 3.49 ± 0.0
3.102AlaVal: 3.102 ± 0.0
0.775AlaTrp: 0.775 ± 0.0
0.388AlaTyr: 0.388 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.775CysAla: 0.775 ± 0.0
0.388CysCys: 0.388 ± 0.0
0.388CysAsp: 0.388 ± 0.0
0.388CysGlu: 0.388 ± 0.0
0.775CysPhe: 0.775 ± 0.0
2.326CysGly: 2.326 ± 0.0
0.388CysHis: 0.388 ± 0.0
1.163CysIle: 1.163 ± 0.0
0.775CysLys: 0.775 ± 0.0
2.326CysLeu: 2.326 ± 0.0
0.0CysMet: 0.0 ± 0.0
1.939CysAsn: 1.939 ± 0.0
0.775CysPro: 0.775 ± 0.0
0.775CysGln: 0.775 ± 0.0
1.551CysArg: 1.551 ± 0.0
2.714CysSer: 2.714 ± 0.0
0.775CysThr: 0.775 ± 0.0
0.388CysVal: 0.388 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.163CysTyr: 1.163 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
0.388AspAla: 0.388 ± 0.0
1.163AspCys: 1.163 ± 0.0
4.265AspAsp: 4.265 ± 0.0
3.102AspGlu: 3.102 ± 0.0
5.428AspPhe: 5.428 ± 0.0
2.326AspGly: 2.326 ± 0.0
0.388AspHis: 0.388 ± 0.0
3.102AspIle: 3.102 ± 0.0
2.326AspLys: 2.326 ± 0.0
7.755AspLeu: 7.755 ± 0.0
1.939AspMet: 1.939 ± 0.0
1.939AspAsn: 1.939 ± 0.0
1.939AspPro: 1.939 ± 0.0
3.49AspGln: 3.49 ± 0.0
3.49AspArg: 3.49 ± 0.0
4.653AspSer: 4.653 ± 0.0
1.551AspThr: 1.551 ± 0.0
3.102AspVal: 3.102 ± 0.0
0.0AspTrp: 0.0 ± 0.0
3.102AspTyr: 3.102 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
2.714GluAla: 2.714 ± 0.0
0.388GluCys: 0.388 ± 0.0
1.939GluAsp: 1.939 ± 0.0
3.49GluGlu: 3.49 ± 0.0
5.428GluPhe: 5.428 ± 0.0
5.041GluGly: 5.041 ± 0.0
2.714GluHis: 2.714 ± 0.0
3.102GluIle: 3.102 ± 0.0
3.49GluLys: 3.49 ± 0.0
2.714GluLeu: 2.714 ± 0.0
3.49GluMet: 3.49 ± 0.0
3.102GluAsn: 3.102 ± 0.0
1.163GluPro: 1.163 ± 0.0
0.775GluGln: 0.775 ± 0.0
3.49GluArg: 3.49 ± 0.0
4.265GluSer: 4.265 ± 0.0
1.551GluThr: 1.551 ± 0.0
6.592GluVal: 6.592 ± 0.0
1.163GluTrp: 1.163 ± 0.0
3.49GluTyr: 3.49 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
0.388PheAla: 0.388 ± 0.0
1.551PheCys: 1.551 ± 0.0
3.49PheAsp: 3.49 ± 0.0
3.49PheGlu: 3.49 ± 0.0
2.714PhePhe: 2.714 ± 0.0
5.428PheGly: 5.428 ± 0.0
0.388PheHis: 0.388 ± 0.0
1.551PheIle: 1.551 ± 0.0
3.877PheLys: 3.877 ± 0.0
5.428PheLeu: 5.428 ± 0.0
0.775PheMet: 0.775 ± 0.0
2.714PheAsn: 2.714 ± 0.0
2.714PhePro: 2.714 ± 0.0
3.102PheGln: 3.102 ± 0.0
2.326PheArg: 2.326 ± 0.0
6.204PheSer: 6.204 ± 0.0
1.551PheThr: 1.551 ± 0.0
4.265PheVal: 4.265 ± 0.0
0.388PheTrp: 0.388 ± 0.0
2.326PheTyr: 2.326 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
4.265GlyAla: 4.265 ± 0.0
0.388GlyCys: 0.388 ± 0.0
5.816GlyAsp: 5.816 ± 0.0
1.939GlyGlu: 1.939 ± 0.0
4.265GlyPhe: 4.265 ± 0.0
4.653GlyGly: 4.653 ± 0.0
1.163GlyHis: 1.163 ± 0.0
2.714GlyIle: 2.714 ± 0.0
2.714GlyLys: 2.714 ± 0.0
5.816GlyLeu: 5.816 ± 0.0
1.551GlyMet: 1.551 ± 0.0
2.714GlyAsn: 2.714 ± 0.0
2.714GlyPro: 2.714 ± 0.0
2.326GlyGln: 2.326 ± 0.0
3.49GlyArg: 3.49 ± 0.0
9.306GlySer: 9.306 ± 0.0
5.816GlyThr: 5.816 ± 0.0
5.816GlyVal: 5.816 ± 0.0
0.0GlyTrp: 0.0 ± 0.0
3.877GlyTyr: 3.877 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.163HisAla: 1.163 ± 0.0
0.388HisCys: 0.388 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.939HisGlu: 1.939 ± 0.0
1.551HisPhe: 1.551 ± 0.0
0.388HisGly: 0.388 ± 0.0
0.388HisHis: 0.388 ± 0.0
1.163HisIle: 1.163 ± 0.0
1.163HisLys: 1.163 ± 0.0
1.551HisLeu: 1.551 ± 0.0
1.163HisMet: 1.163 ± 0.0
1.939HisAsn: 1.939 ± 0.0
0.775HisPro: 0.775 ± 0.0
1.163HisGln: 1.163 ± 0.0
0.388HisArg: 0.388 ± 0.0
1.551HisSer: 1.551 ± 0.0
0.388HisThr: 0.388 ± 0.0
2.714HisVal: 2.714 ± 0.0
0.0HisTrp: 0.0 ± 0.0
2.714HisTyr: 2.714 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.102IleAla: 3.102 ± 0.0
0.388IleCys: 0.388 ± 0.0
4.653IleAsp: 4.653 ± 0.0
3.49IleGlu: 3.49 ± 0.0
2.326IlePhe: 2.326 ± 0.0
5.041IleGly: 5.041 ± 0.0
1.551IleHis: 1.551 ± 0.0
5.041IleIle: 5.041 ± 0.0
3.49IleLys: 3.49 ± 0.0
5.428IleLeu: 5.428 ± 0.0
0.388IleMet: 0.388 ± 0.0
1.939IleAsn: 1.939 ± 0.0
3.102IlePro: 3.102 ± 0.0
1.163IleGln: 1.163 ± 0.0
3.49IleArg: 3.49 ± 0.0
5.816IleSer: 5.816 ± 0.0
3.49IleThr: 3.49 ± 0.0
4.265IleVal: 4.265 ± 0.0
0.0IleTrp: 0.0 ± 0.0
2.714IleTyr: 2.714 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
1.551LysAla: 1.551 ± 0.0
0.0LysCys: 0.0 ± 0.0
2.714LysAsp: 2.714 ± 0.0
2.714LysGlu: 2.714 ± 0.0
1.939LysPhe: 1.939 ± 0.0
2.326LysGly: 2.326 ± 0.0
1.163LysHis: 1.163 ± 0.0
5.041LysIle: 5.041 ± 0.0
3.877LysLys: 3.877 ± 0.0
4.265LysLeu: 4.265 ± 0.0
0.775LysMet: 0.775 ± 0.0
2.714LysAsn: 2.714 ± 0.0
4.653LysPro: 4.653 ± 0.0
1.163LysGln: 1.163 ± 0.0
3.102LysArg: 3.102 ± 0.0
6.592LysSer: 6.592 ± 0.0
4.653LysThr: 4.653 ± 0.0
3.102LysVal: 3.102 ± 0.0
0.388LysTrp: 0.388 ± 0.0
2.326LysTyr: 2.326 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
4.265LeuAla: 4.265 ± 0.0
0.388LeuCys: 0.388 ± 0.0
7.755LeuAsp: 7.755 ± 0.0
4.653LeuGlu: 4.653 ± 0.0
3.102LeuPhe: 3.102 ± 0.0
6.592LeuGly: 6.592 ± 0.0
1.939LeuHis: 1.939 ± 0.0
2.714LeuIle: 2.714 ± 0.0
5.816LeuLys: 5.816 ± 0.0
7.367LeuLeu: 7.367 ± 0.0
1.939LeuMet: 1.939 ± 0.0
2.326LeuAsn: 2.326 ± 0.0
2.326LeuPro: 2.326 ± 0.0
2.326LeuGln: 2.326 ± 0.0
4.653LeuArg: 4.653 ± 0.0
5.428LeuSer: 5.428 ± 0.0
3.49LeuThr: 3.49 ± 0.0
6.592LeuVal: 6.592 ± 0.0
1.163LeuTrp: 1.163 ± 0.0
1.939LeuTyr: 1.939 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
0.388MetAla: 0.388 ± 0.0
0.775MetCys: 0.775 ± 0.0
1.163MetAsp: 1.163 ± 0.0
1.163MetGlu: 1.163 ± 0.0
0.388MetPhe: 0.388 ± 0.0
1.939MetGly: 1.939 ± 0.0
0.388MetHis: 0.388 ± 0.0
1.939MetIle: 1.939 ± 0.0
2.326MetLys: 2.326 ± 0.0
1.163MetLeu: 1.163 ± 0.0
0.0MetMet: 0.0 ± 0.0
1.939MetAsn: 1.939 ± 0.0
1.163MetPro: 1.163 ± 0.0
0.388MetGln: 0.388 ± 0.0
0.775MetArg: 0.775 ± 0.0
1.939MetSer: 1.939 ± 0.0
0.388MetThr: 0.388 ± 0.0
1.939MetVal: 1.939 ± 0.0
0.0MetTrp: 0.0 ± 0.0
1.551MetTyr: 1.551 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.326AsnAla: 2.326 ± 0.0
2.326AsnCys: 2.326 ± 0.0
2.326AsnAsp: 2.326 ± 0.0
1.163AsnGlu: 1.163 ± 0.0
2.326AsnPhe: 2.326 ± 0.0
4.265AsnGly: 4.265 ± 0.0
0.388AsnHis: 0.388 ± 0.0
3.877AsnIle: 3.877 ± 0.0
2.714AsnLys: 2.714 ± 0.0
1.939AsnLeu: 1.939 ± 0.0
1.163AsnMet: 1.163 ± 0.0
1.939AsnAsn: 1.939 ± 0.0
2.326AsnPro: 2.326 ± 0.0
2.326AsnGln: 2.326 ± 0.0
1.939AsnArg: 1.939 ± 0.0
5.041AsnSer: 5.041 ± 0.0
2.326AsnThr: 2.326 ± 0.0
3.49AsnVal: 3.49 ± 0.0
0.775AsnTrp: 0.775 ± 0.0
1.551AsnTyr: 1.551 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
1.163ProAla: 1.163 ± 0.0
1.163ProCys: 1.163 ± 0.0
0.775ProAsp: 0.775 ± 0.0
5.041ProGlu: 5.041 ± 0.0
2.714ProPhe: 2.714 ± 0.0
3.877ProGly: 3.877 ± 0.0
1.939ProHis: 1.939 ± 0.0
1.163ProIle: 1.163 ± 0.0
2.326ProLys: 2.326 ± 0.0
3.49ProLeu: 3.49 ± 0.0
0.775ProMet: 0.775 ± 0.0
2.326ProAsn: 2.326 ± 0.0
3.102ProPro: 3.102 ± 0.0
1.163ProGln: 1.163 ± 0.0
3.877ProArg: 3.877 ± 0.0
3.49ProSer: 3.49 ± 0.0
2.714ProThr: 2.714 ± 0.0
3.49ProVal: 3.49 ± 0.0
0.0ProTrp: 0.0 ± 0.0
1.551ProTyr: 1.551 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
1.551GlnAla: 1.551 ± 0.0
0.775GlnCys: 0.775 ± 0.0
0.388GlnAsp: 0.388 ± 0.0
3.877GlnGlu: 3.877 ± 0.0
1.163GlnPhe: 1.163 ± 0.0
1.551GlnGly: 1.551 ± 0.0
0.0GlnHis: 0.0 ± 0.0
2.714GlnIle: 2.714 ± 0.0
1.939GlnLys: 1.939 ± 0.0
2.326GlnLeu: 2.326 ± 0.0
0.0GlnMet: 0.0 ± 0.0
0.388GlnAsn: 0.388 ± 0.0
1.551GlnPro: 1.551 ± 0.0
0.775GlnGln: 0.775 ± 0.0
2.714GlnArg: 2.714 ± 0.0
1.551GlnSer: 1.551 ± 0.0
1.939GlnThr: 1.939 ± 0.0
3.102GlnVal: 3.102 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
2.326GlnTyr: 2.326 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.326ArgAla: 2.326 ± 0.0
1.163ArgCys: 1.163 ± 0.0
5.041ArgAsp: 5.041 ± 0.0
3.877ArgGlu: 3.877 ± 0.0
1.551ArgPhe: 1.551 ± 0.0
2.714ArgGly: 2.714 ± 0.0
1.163ArgHis: 1.163 ± 0.0
5.041ArgIle: 5.041 ± 0.0
3.102ArgLys: 3.102 ± 0.0
2.326ArgLeu: 2.326 ± 0.0
0.775ArgMet: 0.775 ± 0.0
2.714ArgAsn: 2.714 ± 0.0
1.939ArgPro: 1.939 ± 0.0
1.163ArgGln: 1.163 ± 0.0
5.428ArgArg: 5.428 ± 0.0
2.714ArgSer: 2.714 ± 0.0
2.714ArgThr: 2.714 ± 0.0
8.53ArgVal: 8.53 ± 0.0
0.0ArgTrp: 0.0 ± 0.0
3.877ArgTyr: 3.877 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
5.041SerAla: 5.041 ± 0.0
1.163SerCys: 1.163 ± 0.0
5.816SerAsp: 5.816 ± 0.0
5.041SerGlu: 5.041 ± 0.0
5.041SerPhe: 5.041 ± 0.0
5.041SerGly: 5.041 ± 0.0
1.939SerHis: 1.939 ± 0.0
6.204SerIle: 6.204 ± 0.0
2.714SerLys: 2.714 ± 0.0
5.816SerLeu: 5.816 ± 0.0
3.102SerMet: 3.102 ± 0.0
3.877SerAsn: 3.877 ± 0.0
4.265SerPro: 4.265 ± 0.0
1.939SerGln: 1.939 ± 0.0
6.979SerArg: 6.979 ± 0.0
8.143SerSer: 8.143 ± 0.0
5.816SerThr: 5.816 ± 0.0
8.918SerVal: 8.918 ± 0.0
0.388SerTrp: 0.388 ± 0.0
0.775SerTyr: 0.775 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
4.653ThrAla: 4.653 ± 0.0
1.163ThrCys: 1.163 ± 0.0
0.775ThrAsp: 0.775 ± 0.0
1.939ThrGlu: 1.939 ± 0.0
4.265ThrPhe: 4.265 ± 0.0
5.816ThrGly: 5.816 ± 0.0
0.388ThrHis: 0.388 ± 0.0
3.49ThrIle: 3.49 ± 0.0
1.551ThrLys: 1.551 ± 0.0
5.041ThrLeu: 5.041 ± 0.0
1.163ThrMet: 1.163 ± 0.0
2.714ThrAsn: 2.714 ± 0.0
2.326ThrPro: 2.326 ± 0.0
1.551ThrGln: 1.551 ± 0.0
2.714ThrArg: 2.714 ± 0.0
3.49ThrSer: 3.49 ± 0.0
4.265ThrThr: 4.265 ± 0.0
3.49ThrVal: 3.49 ± 0.0
0.775ThrTrp: 0.775 ± 0.0
2.714ThrTyr: 2.714 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
5.428ValAla: 5.428 ± 0.0
1.939ValCys: 1.939 ± 0.0
4.265ValAsp: 4.265 ± 0.0
6.592ValGlu: 6.592 ± 0.0
5.428ValPhe: 5.428 ± 0.0
4.265ValGly: 4.265 ± 0.0
1.939ValHis: 1.939 ± 0.0
3.49ValIle: 3.49 ± 0.0
4.265ValLys: 4.265 ± 0.0
7.367ValLeu: 7.367 ± 0.0
1.163ValMet: 1.163 ± 0.0
4.653ValAsn: 4.653 ± 0.0
5.816ValPro: 5.816 ± 0.0
2.326ValGln: 2.326 ± 0.0
2.714ValArg: 2.714 ± 0.0
6.979ValSer: 6.979 ± 0.0
5.041ValThr: 5.041 ± 0.0
8.143ValVal: 8.143 ± 0.0
0.0ValTrp: 0.0 ± 0.0
3.102ValTyr: 3.102 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.388TrpAla: 0.388 ± 0.0
0.388TrpCys: 0.388 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.775TrpPhe: 0.775 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.163TrpIle: 1.163 ± 0.0
0.388TrpLys: 0.388 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.388TrpMet: 0.388 ± 0.0
0.388TrpAsn: 0.388 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.775TrpArg: 0.775 ± 0.0
0.775TrpSer: 0.775 ± 0.0
0.775TrpThr: 0.775 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.388TrpTyr: 0.388 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.163TyrAla: 1.163 ± 0.0
3.102TyrCys: 3.102 ± 0.0
1.551TyrAsp: 1.551 ± 0.0
3.49TyrGlu: 3.49 ± 0.0
1.163TyrPhe: 1.163 ± 0.0
1.939TyrGly: 1.939 ± 0.0
1.939TyrHis: 1.939 ± 0.0
2.714TyrIle: 2.714 ± 0.0
4.265TyrLys: 4.265 ± 0.0
2.714TyrLeu: 2.714 ± 0.0
0.388TyrMet: 0.388 ± 0.0
1.163TyrAsn: 1.163 ± 0.0
1.551TyrPro: 1.551 ± 0.0
1.551TyrGln: 1.551 ± 0.0
3.102TyrArg: 3.102 ± 0.0
3.49TyrSer: 3.49 ± 0.0
1.551TyrThr: 1.551 ± 0.0
4.265TyrVal: 4.265 ± 0.0
0.775TyrTrp: 0.775 ± 0.0
1.163TyrTyr: 1.163 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (2580 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski