Amino acid dipepetide frequency for Planctomyces bekefii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	13.483AlaAla: 13.483 ± 0.218	1.178AlaCys: 1.178 ± 0.044	6.198AlaAsp: 6.198 ± 0.1	6.916AlaGlu: 6.916 ± 0.134	3.33AlaPhe: 3.33 ± 0.074	9.765AlaGly: 9.765 ± 0.14	1.461AlaHis: 1.461 ± 0.04	4.503AlaIle: 4.503 ± 0.086	3.251AlaLys: 3.251 ± 0.088	8.89AlaLeu: 8.89 ± 0.132	2.165AlaMet: 2.165 ± 0.058	2.523AlaAsn: 2.523 ± 0.059	3.953AlaPro: 3.953 ± 0.091	3.298AlaGln: 3.298 ± 0.072	5.829AlaArg: 5.829 ± 0.103	5.731AlaSer: 5.731 ± 0.098	5.11AlaThr: 5.11 ± 0.089	8.013AlaVal: 8.013 ± 0.138	1.558AlaTrp: 1.558 ± 0.056	1.691AlaTyr: 1.691 ± 0.049	0.0AlaXaa: 0.0 ± 0.0
Cys	1.008CysAla: 1.008 ± 0.041	0.289CysCys: 0.289 ± 0.021	0.649CysAsp: 0.649 ± 0.033	0.693CysGlu: 0.693 ± 0.033	0.537CysPhe: 0.537 ± 0.028	1.191CysGly: 1.191 ± 0.039	0.421CysHis: 0.421 ± 0.027	0.482CysIle: 0.482 ± 0.027	0.282CysLys: 0.282 ± 0.023	1.329CysLeu: 1.329 ± 0.042	0.23CysMet: 0.23 ± 0.018	0.354CysAsn: 0.354 ± 0.023	0.6CysPro: 0.6 ± 0.029	0.453CysGln: 0.453 ± 0.026	1.023CysArg: 1.023 ± 0.044	0.931CysSer: 0.931 ± 0.035	0.541CysThr: 0.541 ± 0.029	0.932CysVal: 0.932 ± 0.039	0.252CysTrp: 0.252 ± 0.022	0.31CysTyr: 0.31 ± 0.021	0.0CysXaa: 0.0 ± 0.0
Asp	5.196AspAla: 5.196 ± 0.099	0.664AspCys: 0.664 ± 0.028	2.929AspAsp: 2.929 ± 0.075	3.351AspGlu: 3.351 ± 0.077	2.552AspPhe: 2.552 ± 0.056	4.822AspGly: 4.822 ± 0.097	1.15AspHis: 1.15 ± 0.042	2.47AspIle: 2.47 ± 0.073	1.539AspLys: 1.539 ± 0.054	5.743AspLeu: 5.743 ± 0.105	0.954AspMet: 0.954 ± 0.034	1.46AspAsn: 1.46 ± 0.051	3.185AspPro: 3.185 ± 0.071	2.258AspGln: 2.258 ± 0.062	4.05AspArg: 4.05 ± 0.076	3.508AspSer: 3.508 ± 0.076	2.294AspThr: 2.294 ± 0.063	3.845AspVal: 3.845 ± 0.071	0.974AspTrp: 0.974 ± 0.037	1.522AspTyr: 1.522 ± 0.048	0.0AspXaa: 0.0 ± 0.0
Glu	5.378GluAla: 5.378 ± 0.114	0.653GluCys: 0.653 ± 0.031	2.728GluAsp: 2.728 ± 0.07	3.045GluGlu: 3.045 ± 0.088	2.464GluPhe: 2.464 ± 0.063	3.864GluGly: 3.864 ± 0.124	1.263GluHis: 1.263 ± 0.041	3.389GluIle: 3.389 ± 0.084	2.664GluLys: 2.664 ± 0.08	6.899GluLeu: 6.899 ± 0.105	1.344GluMet: 1.344 ± 0.039	1.942GluAsn: 1.942 ± 0.056	2.489GluPro: 2.489 ± 0.071	3.215GluGln: 3.215 ± 0.073	4.326GluArg: 4.326 ± 0.091	4.092GluSer: 4.092 ± 0.078	3.209GluThr: 3.209 ± 0.063	3.964GluVal: 3.964 ± 0.078	0.767GluTrp: 0.767 ± 0.038	1.507GluTyr: 1.507 ± 0.048	0.0GluXaa: 0.0 ± 0.0
Phe	3.662PheAla: 3.662 ± 0.078	0.604PheCys: 0.604 ± 0.028	2.428PheAsp: 2.428 ± 0.053	2.384PheGlu: 2.384 ± 0.063	1.633PhePhe: 1.633 ± 0.055	3.444PheGly: 3.444 ± 0.08	0.843PheHis: 0.843 ± 0.035	1.526PheIle: 1.526 ± 0.047	1.06PheLys: 1.06 ± 0.042	3.926PheLeu: 3.926 ± 0.077	0.708PheMet: 0.708 ± 0.03	1.326PheAsn: 1.326 ± 0.048	1.755PhePro: 1.755 ± 0.058	1.575PheGln: 1.575 ± 0.047	2.94PheArg: 2.94 ± 0.061	2.833PheSer: 2.833 ± 0.054	1.956PheThr: 1.956 ± 0.062	2.741PheVal: 2.741 ± 0.063	0.567PheTrp: 0.567 ± 0.03	1.077PheTyr: 1.077 ± 0.04	0.0PheXaa: 0.0 ± 0.0
Gly	6.797GlyAla: 6.797 ± 0.117	1.104GlyCys: 1.104 ± 0.038	4.343GlyAsp: 4.343 ± 0.091	4.49GlyGlu: 4.49 ± 0.097	3.44GlyPhe: 3.44 ± 0.066	7.249GlyGly: 7.249 ± 0.161	1.644GlyHis: 1.644 ± 0.049	3.885GlyIle: 3.885 ± 0.075	3.11GlyLys: 3.11 ± 0.074	8.043GlyLeu: 8.043 ± 0.127	1.994GlyMet: 1.994 ± 0.05	2.643GlyAsn: 2.643 ± 0.117	3.118GlyPro: 3.118 ± 0.082	3.253GlyGln: 3.253 ± 0.069	6.16GlyArg: 6.16 ± 0.113	5.569GlySer: 5.569 ± 0.103	4.642GlyThr: 4.642 ± 0.118	5.787GlyVal: 5.787 ± 0.098	1.334GlyTrp: 1.334 ± 0.041	2.044GlyTyr: 2.044 ± 0.057	0.0GlyXaa: 0.0 ± 0.0
His	1.828HisAla: 1.828 ± 0.054	0.343HisCys: 0.343 ± 0.019	1.025HisAsp: 1.025 ± 0.041	1.124HisGlu: 1.124 ± 0.04	0.868HisPhe: 0.868 ± 0.033	1.801HisGly: 1.801 ± 0.062	0.639HisHis: 0.639 ± 0.032	0.811HisIle: 0.811 ± 0.034	0.559HisLys: 0.559 ± 0.031	2.119HisLeu: 2.119 ± 0.05	0.41HisMet: 0.41 ± 0.024	0.635HisAsn: 0.635 ± 0.03	1.447HisPro: 1.447 ± 0.045	0.781HisGln: 0.781 ± 0.037	1.43HisArg: 1.43 ± 0.049	1.333HisSer: 1.333 ± 0.044	0.949HisThr: 0.949 ± 0.035	1.255HisVal: 1.255 ± 0.039	0.396HisTrp: 0.396 ± 0.025	0.605HisTyr: 0.605 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	4.669IleAla: 4.669 ± 0.079	0.751IleCys: 0.751 ± 0.034	3.035IleAsp: 3.035 ± 0.072	3.041IleGlu: 3.041 ± 0.07	1.641IlePhe: 1.641 ± 0.046	3.516IleGly: 3.516 ± 0.074	0.968IleHis: 0.968 ± 0.037	1.948IleIle: 1.948 ± 0.061	1.509IleLys: 1.509 ± 0.069	4.385IleLeu: 4.385 ± 0.086	0.75IleMet: 0.75 ± 0.034	1.696IleAsn: 1.696 ± 0.059	2.653IlePro: 2.653 ± 0.066	1.719IleGln: 1.719 ± 0.054	3.621IleArg: 3.621 ± 0.066	3.582IleSer: 3.582 ± 0.083	2.505IleThr: 2.505 ± 0.074	3.318IleVal: 3.318 ± 0.07	0.638IleTrp: 0.638 ± 0.029	1.123IleTyr: 1.123 ± 0.039	0.0IleXaa: 0.0 ± 0.0
Lys	3.265LysAla: 3.265 ± 0.089	0.297LysCys: 0.297 ± 0.02	1.728LysAsp: 1.728 ± 0.061	1.864LysGlu: 1.864 ± 0.065	1.355LysPhe: 1.355 ± 0.041	2.139LysGly: 2.139 ± 0.075	0.698LysHis: 0.698 ± 0.035	2.027LysIle: 2.027 ± 0.075	2.097LysLys: 2.097 ± 0.094	3.63LysLeu: 3.63 ± 0.089	0.781LysMet: 0.781 ± 0.037	1.418LysAsn: 1.418 ± 0.055	1.898LysPro: 1.898 ± 0.058	1.48LysGln: 1.48 ± 0.049	2.019LysArg: 2.019 ± 0.056	2.568LysSer: 2.568 ± 0.072	2.227LysThr: 2.227 ± 0.094	2.374LysVal: 2.374 ± 0.073	0.442LysTrp: 0.442 ± 0.024	0.987LysTyr: 0.987 ± 0.036	0.0LysXaa: 0.0 ± 0.0
Leu	10.636LeuAla: 10.636 ± 0.131	1.254LeuCys: 1.254 ± 0.043	5.403LeuAsp: 5.403 ± 0.09	5.922LeuGlu: 5.922 ± 0.101	3.558LeuPhe: 3.558 ± 0.064	7.154LeuGly: 7.154 ± 0.096	2.08LeuHis: 2.08 ± 0.058	4.6LeuIle: 4.6 ± 0.085	4.344LeuLys: 4.344 ± 0.099	12.198LeuLeu: 12.198 ± 0.194	2.086LeuMet: 2.086 ± 0.058	3.494LeuAsn: 3.494 ± 0.082	5.657LeuPro: 5.657 ± 0.104	5.764LeuGln: 5.764 ± 0.114	7.507LeuArg: 7.507 ± 0.119	7.237LeuSer: 7.237 ± 0.093	6.081LeuThr: 6.081 ± 0.099	6.985LeuVal: 6.985 ± 0.094	1.355LeuTrp: 1.355 ± 0.055	2.216LeuTyr: 2.216 ± 0.059	0.0LeuXaa: 0.0 ± 0.0
Met	2.086MetAla: 2.086 ± 0.062	0.225MetCys: 0.225 ± 0.015	1.01MetAsp: 1.01 ± 0.038	1.057MetGlu: 1.057 ± 0.037	0.744MetPhe: 0.744 ± 0.035	1.413MetGly: 1.413 ± 0.047	0.42MetHis: 0.42 ± 0.023	1.079MetIle: 1.079 ± 0.041	0.953MetLys: 0.953 ± 0.036	2.418MetLeu: 2.418 ± 0.061	0.541MetMet: 0.541 ± 0.028	0.785MetAsn: 0.785 ± 0.033	1.158MetPro: 1.158 ± 0.042	1.048MetGln: 1.048 ± 0.037	1.344MetArg: 1.344 ± 0.045	1.56MetSer: 1.56 ± 0.041	1.35MetThr: 1.35 ± 0.041	1.334MetVal: 1.334 ± 0.04	0.217MetTrp: 0.217 ± 0.018	0.382MetTyr: 0.382 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	2.741AsnAla: 2.741 ± 0.07	0.449AsnCys: 0.449 ± 0.022	1.646AsnAsp: 1.646 ± 0.055	1.494AsnGlu: 1.494 ± 0.05	1.343AsnPhe: 1.343 ± 0.044	2.631AsnGly: 2.631 ± 0.079	0.649AsnHis: 0.649 ± 0.03	1.557AsnIle: 1.557 ± 0.056	1.054AsnLys: 1.054 ± 0.095	3.202AsnLeu: 3.202 ± 0.07	0.607AsnMet: 0.607 ± 0.028	1.189AsnAsn: 1.189 ± 0.058	2.16AsnPro: 2.16 ± 0.061	1.281AsnGln: 1.281 ± 0.047	2.223AsnArg: 2.223 ± 0.064	2.442AsnSer: 2.442 ± 0.067	1.541AsnThr: 1.541 ± 0.067	2.035AsnVal: 2.035 ± 0.063	0.517AsnTrp: 0.517 ± 0.027	0.909AsnTyr: 0.909 ± 0.037	0.0AsnXaa: 0.0 ± 0.0
Pro	6.052ProAla: 6.052 ± 0.129	0.44ProCys: 0.44 ± 0.026	3.261ProAsp: 3.261 ± 0.066	3.964ProGlu: 3.964 ± 0.076	1.687ProPhe: 1.687 ± 0.05	4.523ProGly: 4.523 ± 0.085	0.962ProHis: 0.962 ± 0.035	1.931ProIle: 1.931 ± 0.046	1.616ProLys: 1.616 ± 0.058	4.83ProLeu: 4.83 ± 0.069	0.982ProMet: 0.982 ± 0.036	1.491ProAsn: 1.491 ± 0.056	2.371ProPro: 2.371 ± 0.073	2.242ProGln: 2.242 ± 0.067	2.715ProArg: 2.715 ± 0.07	2.691ProSer: 2.691 ± 0.062	2.388ProThr: 2.388 ± 0.063	3.906ProVal: 3.906 ± 0.069	0.848ProTrp: 0.848 ± 0.038	0.986ProTyr: 0.986 ± 0.036	0.0ProXaa: 0.0 ± 0.0
Gln	4.167GlnAla: 4.167 ± 0.086	0.419GlnCys: 0.419 ± 0.023	1.901GlnAsp: 1.901 ± 0.049	2.254GlnGlu: 2.254 ± 0.064	1.765GlnPhe: 1.765 ± 0.047	2.685GlnGly: 2.685 ± 0.069	1.011GlnHis: 1.011 ± 0.035	2.334GlnIle: 2.334 ± 0.059	1.821GlnLys: 1.821 ± 0.053	5.093GlnLeu: 5.093 ± 0.089	1.011GlnMet: 1.011 ± 0.038	1.398GlnAsn: 1.398 ± 0.047	2.382GlnPro: 2.382 ± 0.064	2.902GlnGln: 2.902 ± 0.08	3.316GlnArg: 3.316 ± 0.083	2.807GlnSer: 2.807 ± 0.056	2.32GlnThr: 2.32 ± 0.066	2.894GlnVal: 2.894 ± 0.073	0.596GlnTrp: 0.596 ± 0.029	0.985GlnTyr: 0.985 ± 0.037	0.0GlnXaa: 0.0 ± 0.0
Arg	5.408ArgAla: 5.408 ± 0.096	0.817ArgCys: 0.817 ± 0.036	3.624ArgAsp: 3.624 ± 0.068	4.333ArgGlu: 4.333 ± 0.087	3.046ArgPhe: 3.046 ± 0.062	4.933ArgGly: 4.933 ± 0.092	1.553ArgHis: 1.553 ± 0.037	3.743ArgIle: 3.743 ± 0.087	2.248ArgLys: 2.248 ± 0.064	8.274ArgLeu: 8.274 ± 0.117	1.747ArgMet: 1.747 ± 0.044	2.212ArgAsn: 2.212 ± 0.056	3.244ArgPro: 3.244 ± 0.075	3.436ArgGln: 3.436 ± 0.082	5.982ArgArg: 5.982 ± 0.116	4.526ArgSer: 4.526 ± 0.099	3.482ArgThr: 3.482 ± 0.069	4.753ArgVal: 4.753 ± 0.083	1.179ArgTrp: 1.179 ± 0.045	1.724ArgTyr: 1.724 ± 0.052	0.0ArgXaa: 0.0 ± 0.0
Ser	6.748SerAla: 6.748 ± 0.102	0.739SerCys: 0.739 ± 0.032	3.634SerAsp: 3.634 ± 0.064	4.207SerGlu: 4.207 ± 0.079	2.54SerPhe: 2.54 ± 0.056	6.78SerGly: 6.78 ± 0.127	1.297SerHis: 1.297 ± 0.044	3.03SerIle: 3.03 ± 0.072	2.061SerLys: 2.061 ± 0.067	7.014SerLeu: 7.014 ± 0.115	1.44SerMet: 1.44 ± 0.044	1.905SerAsn: 1.905 ± 0.061	3.386SerPro: 3.386 ± 0.073	2.605SerGln: 2.605 ± 0.065	4.569SerArg: 4.569 ± 0.077	4.444SerSer: 4.444 ± 0.103	3.463SerThr: 3.463 ± 0.083	4.7SerVal: 4.7 ± 0.082	1.049SerTrp: 1.049 ± 0.04	1.405SerTyr: 1.405 ± 0.046	0.0SerXaa: 0.0 ± 0.0
Thr	6.016ThrAla: 6.016 ± 0.115	0.563ThrCys: 0.563 ± 0.027	2.975ThrAsp: 2.975 ± 0.075	2.993ThrGlu: 2.993 ± 0.095	1.908ThrPhe: 1.908 ± 0.062	5.015ThrGly: 5.015 ± 0.102	0.996ThrHis: 0.996 ± 0.035	2.564ThrIle: 2.564 ± 0.075	1.585ThrLys: 1.585 ± 0.045	5.313ThrLeu: 5.313 ± 0.092	1.054ThrMet: 1.054 ± 0.033	1.516ThrAsn: 1.516 ± 0.057	3.055ThrPro: 3.055 ± 0.08	1.841ThrGln: 1.841 ± 0.053	2.865ThrArg: 2.865 ± 0.067	3.34ThrSer: 3.34 ± 0.082	2.982ThrThr: 2.982 ± 0.097	4.414ThrVal: 4.414 ± 0.098	0.822ThrTrp: 0.822 ± 0.029	1.112ThrTyr: 1.112 ± 0.048	0.0ThrXaa: 0.0 ± 0.0
Val	6.7ValAla: 6.7 ± 0.105	1.088ValCys: 1.088 ± 0.045	3.868ValAsp: 3.868 ± 0.082	4.104ValGlu: 4.104 ± 0.081	2.892ValPhe: 2.892 ± 0.064	4.704ValGly: 4.704 ± 0.099	1.444ValHis: 1.444 ± 0.049	3.534ValIle: 3.534 ± 0.073	2.136ValLys: 2.136 ± 0.062	7.877ValLeu: 7.877 ± 0.121	1.533ValMet: 1.533 ± 0.048	2.221ValAsn: 2.221 ± 0.06	3.605ValPro: 3.605 ± 0.075	2.984ValGln: 2.984 ± 0.067	5.259ValArg: 5.259 ± 0.097	5.094ValSer: 5.094 ± 0.094	3.962ValThr: 3.962 ± 0.093	5.761ValVal: 5.761 ± 0.123	1.095ValTrp: 1.095 ± 0.042	1.642ValTyr: 1.642 ± 0.051	0.0ValXaa: 0.0 ± 0.0
Trp	1.033TrpAla: 1.033 ± 0.037	0.257TrpCys: 0.257 ± 0.02	0.793TrpAsp: 0.793 ± 0.03	0.667TrpGlu: 0.667 ± 0.031	0.596TrpPhe: 0.596 ± 0.034	0.995TrpGly: 0.995 ± 0.039	0.354TrpHis: 0.354 ± 0.021	0.792TrpIle: 0.792 ± 0.032	0.688TrpLys: 0.688 ± 0.027	1.913TrpLeu: 1.913 ± 0.058	0.396TrpMet: 0.396 ± 0.021	0.595TrpAsn: 0.595 ± 0.029	0.625TrpPro: 0.625 ± 0.032	0.909TrpGln: 0.909 ± 0.038	1.147TrpArg: 1.147 ± 0.039	1.082TrpSer: 1.082 ± 0.038	0.846TrpThr: 0.846 ± 0.039	0.916TrpVal: 0.916 ± 0.041	0.297TrpTrp: 0.297 ± 0.019	0.408TrpTyr: 0.408 ± 0.025	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.973TyrAla: 1.973 ± 0.055	0.374TyrCys: 0.374 ± 0.026	1.289TyrAsp: 1.289 ± 0.048	1.298TyrGlu: 1.298 ± 0.044	1.087TyrPhe: 1.087 ± 0.039	2.027TyrGly: 2.027 ± 0.052	0.504TyrHis: 0.504 ± 0.026	0.86TyrIle: 0.86 ± 0.038	0.718TyrLys: 0.718 ± 0.039	2.435TyrLeu: 2.435 ± 0.06	0.387TyrMet: 0.387 ± 0.022	0.865TyrAsn: 0.865 ± 0.035	1.146TyrPro: 1.146 ± 0.034	1.016TyrGln: 1.016 ± 0.04	1.935TyrArg: 1.935 ± 0.063	1.649TyrSer: 1.649 ± 0.051	1.082TyrThr: 1.082 ± 0.038	1.581TyrVal: 1.581 ± 0.055	0.406TyrTrp: 0.406 ± 0.024	0.688TyrTyr: 0.688 ± 0.033	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3028 proteins (761673 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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