Amino acid dipepetide frequency for Vigna angularis var. angularis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.926AlaAla: 5.926 ± 0.036	1.263AlaCys: 1.263 ± 0.011	2.894AlaAsp: 2.894 ± 0.019	4.022AlaGlu: 4.022 ± 0.021	2.773AlaPhe: 2.773 ± 0.018	3.788AlaGly: 3.788 ± 0.022	1.319AlaHis: 1.319 ± 0.012	3.658AlaIle: 3.658 ± 0.021	3.758AlaLys: 3.758 ± 0.017	6.492AlaLeu: 6.492 ± 0.031	1.693AlaMet: 1.693 ± 0.013	2.537AlaAsn: 2.537 ± 0.016	2.763AlaPro: 2.763 ± 0.017	2.059AlaGln: 2.059 ± 0.013	3.238AlaArg: 3.238 ± 0.021	5.953AlaSer: 5.953 ± 0.025	3.671AlaThr: 3.671 ± 0.023	4.734AlaVal: 4.734 ± 0.022	0.754AlaTrp: 0.754 ± 0.008	1.763AlaTyr: 1.763 ± 0.015	0.0AlaXaa: 0.0 ± 0.0
Cys	1.024CysAla: 1.024 ± 0.01	0.595CysCys: 0.595 ± 0.008	0.905CysAsp: 0.905 ± 0.011	0.913CysGlu: 0.913 ± 0.011	0.996CysPhe: 0.996 ± 0.01	1.396CysGly: 1.396 ± 0.013	0.536CysHis: 0.536 ± 0.008	1.012CysIle: 1.012 ± 0.01	1.118CysLys: 1.118 ± 0.012	1.905CysLeu: 1.905 ± 0.013	0.471CysMet: 0.471 ± 0.007	0.891CysAsn: 0.891 ± 0.01	0.942CysPro: 0.942 ± 0.01	0.605CysGln: 0.605 ± 0.008	1.047CysArg: 1.047 ± 0.01	1.928CysSer: 1.928 ± 0.015	0.918CysThr: 0.918 ± 0.01	1.194CysVal: 1.194 ± 0.022	0.273CysTrp: 0.273 ± 0.005	0.573CysTyr: 0.573 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	3.326AspAla: 3.326 ± 0.018	0.935AspCys: 0.935 ± 0.01	3.434AspAsp: 3.434 ± 0.024	3.816AspGlu: 3.816 ± 0.024	2.316AspPhe: 2.316 ± 0.015	3.571AspGly: 3.571 ± 0.021	1.237AspHis: 1.237 ± 0.013	2.949AspIle: 2.949 ± 0.016	2.698AspLys: 2.698 ± 0.017	4.888AspLeu: 4.888 ± 0.024	1.295AspMet: 1.295 ± 0.012	2.142AspAsn: 2.142 ± 0.017	2.527AspPro: 2.527 ± 0.017	1.668AspGln: 1.668 ± 0.013	2.254AspArg: 2.254 ± 0.017	4.238AspSer: 4.238 ± 0.024	2.247AspThr: 2.247 ± 0.016	3.588AspVal: 3.588 ± 0.018	0.688AspTrp: 0.688 ± 0.008	1.512AspTyr: 1.512 ± 0.013	0.0AspXaa: 0.0 ± 0.0
Glu	4.558GluAla: 4.558 ± 0.026	0.944GluCys: 0.944 ± 0.011	3.826GluAsp: 3.826 ± 0.023	6.108GluGlu: 6.108 ± 0.041	2.319GluPhe: 2.319 ± 0.015	3.76GluGly: 3.76 ± 0.02	1.3GluHis: 1.3 ± 0.011	3.677GluIle: 3.677 ± 0.019	4.781GluLys: 4.781 ± 0.027	5.745GluLeu: 5.745 ± 0.027	1.695GluMet: 1.695 ± 0.014	3.201GluAsn: 3.201 ± 0.019	2.071GluPro: 2.071 ± 0.014	2.115GluGln: 2.115 ± 0.016	3.399GluArg: 3.399 ± 0.024	4.545GluSer: 4.545 ± 0.024	2.994GluThr: 2.994 ± 0.02	4.136GluVal: 4.136 ± 0.023	0.72GluTrp: 0.72 ± 0.008	1.635GluTyr: 1.635 ± 0.015	0.0GluXaa: 0.0 ± 0.0
Phe	2.457PheAla: 2.457 ± 0.014	0.993PheCys: 0.993 ± 0.01	2.329PheAsp: 2.329 ± 0.015	2.302PheGlu: 2.302 ± 0.012	2.211PhePhe: 2.211 ± 0.019	3.121PheGly: 3.121 ± 0.02	1.253PheHis: 1.253 ± 0.011	2.176PheIle: 2.176 ± 0.016	2.126PheLys: 2.126 ± 0.015	4.591PheLeu: 4.591 ± 0.024	0.994PheMet: 0.994 ± 0.01	1.874PheAsn: 1.874 ± 0.014	2.259PhePro: 2.259 ± 0.016	1.634PheGln: 1.634 ± 0.012	2.126PheArg: 2.126 ± 0.015	4.443PheSer: 4.443 ± 0.022	2.1PheThr: 2.1 ± 0.014	2.871PheVal: 2.871 ± 0.017	0.587PheTrp: 0.587 ± 0.007	1.329PheTyr: 1.329 ± 0.01	0.0PheXaa: 0.0 ± 0.0
Gly	3.722GlyAla: 3.722 ± 0.024	1.319GlyCys: 1.319 ± 0.013	3.223GlyAsp: 3.223 ± 0.023	3.612GlyGlu: 3.612 ± 0.021	3.113GlyPhe: 3.113 ± 0.016	5.094GlyGly: 5.094 ± 0.049	1.548GlyHis: 1.548 ± 0.013	3.522GlyIle: 3.522 ± 0.019	4.072GlyLys: 4.072 ± 0.02	5.735GlyLeu: 5.735 ± 0.025	1.465GlyMet: 1.465 ± 0.013	3.128GlyAsn: 3.128 ± 0.02	2.316GlyPro: 2.316 ± 0.017	1.968GlyGln: 1.968 ± 0.015	3.545GlyArg: 3.545 ± 0.021	5.846GlySer: 5.846 ± 0.029	3.222GlyThr: 3.222 ± 0.019	4.257GlyVal: 4.257 ± 0.023	0.893GlyTrp: 0.893 ± 0.009	2.046GlyTyr: 2.046 ± 0.019	0.0GlyXaa: 0.0 ± 0.0
His	1.541HisAla: 1.541 ± 0.012	0.567HisCys: 0.567 ± 0.008	1.217HisAsp: 1.217 ± 0.011	1.311HisGlu: 1.311 ± 0.01	1.185HisPhe: 1.185 ± 0.011	1.747HisGly: 1.747 ± 0.013	1.144HisHis: 1.144 ± 0.014	1.252HisIle: 1.252 ± 0.012	1.248HisLys: 1.248 ± 0.011	2.537HisLeu: 2.537 ± 0.015	0.586HisMet: 0.586 ± 0.008	1.098HisAsn: 1.098 ± 0.01	1.457HisPro: 1.457 ± 0.012	1.083HisGln: 1.083 ± 0.011	1.467HisArg: 1.467 ± 0.013	2.239HisSer: 2.239 ± 0.015	1.146HisThr: 1.146 ± 0.012	1.715HisVal: 1.715 ± 0.016	0.314HisTrp: 0.314 ± 0.006	0.746HisTyr: 0.746 ± 0.008	0.0HisXaa: 0.0 ± 0.0
Ile	3.481IleAla: 3.481 ± 0.019	1.108IleCys: 1.108 ± 0.011	2.794IleAsp: 2.794 ± 0.016	3.087IleGlu: 3.087 ± 0.021	2.367IlePhe: 2.367 ± 0.015	3.34IleGly: 3.34 ± 0.021	1.38IleHis: 1.38 ± 0.011	2.86IleIle: 2.86 ± 0.019	2.898IleLys: 2.898 ± 0.015	5.292IleLeu: 5.292 ± 0.025	1.181IleMet: 1.181 ± 0.01	2.233IleAsn: 2.233 ± 0.013	2.992IlePro: 2.992 ± 0.023	2.019IleGln: 2.019 ± 0.014	2.6IleArg: 2.6 ± 0.015	4.829IleSer: 4.829 ± 0.021	2.679IleThr: 2.679 ± 0.016	3.471IleVal: 3.471 ± 0.019	0.688IleTrp: 0.688 ± 0.007	1.495IleTyr: 1.495 ± 0.012	0.0IleXaa: 0.0 ± 0.0
Lys	3.868LysAla: 3.868 ± 0.021	0.993LysCys: 0.993 ± 0.011	3.186LysAsp: 3.186 ± 0.019	4.643LysGlu: 4.643 ± 0.029	2.219LysPhe: 2.219 ± 0.014	3.74LysGly: 3.74 ± 0.021	1.475LysHis: 1.475 ± 0.012	3.257LysIle: 3.257 ± 0.018	4.685LysLys: 4.685 ± 0.031	5.951LysLeu: 5.951 ± 0.028	1.512LysMet: 1.512 ± 0.012	2.742LysAsn: 2.742 ± 0.017	2.743LysPro: 2.743 ± 0.02	2.282LysGln: 2.282 ± 0.014	3.64LysArg: 3.64 ± 0.02	4.675LysSer: 4.675 ± 0.023	2.965LysThr: 2.965 ± 0.02	3.959LysVal: 3.959 ± 0.019	0.814LysTrp: 0.814 ± 0.01	1.603LysTyr: 1.603 ± 0.014	0.0LysXaa: 0.0 ± 0.0
Leu	6.297LeuAla: 6.297 ± 0.027	1.976LeuCys: 1.976 ± 0.016	4.963LeuAsp: 4.963 ± 0.023	6.122LeuGlu: 6.122 ± 0.03	4.16LeuPhe: 4.16 ± 0.022	5.653LeuGly: 5.653 ± 0.025	2.866LeuHis: 2.866 ± 0.019	4.592LeuIle: 4.592 ± 0.023	6.176LeuLys: 6.176 ± 0.031	10.256LeuLeu: 10.256 ± 0.047	2.113LeuMet: 2.113 ± 0.013	4.126LeuAsn: 4.126 ± 0.019	5.211LeuPro: 5.211 ± 0.025	4.354LeuGln: 4.354 ± 0.023	5.412LeuArg: 5.412 ± 0.026	8.992LeuSer: 8.992 ± 0.035	4.563LeuThr: 4.563 ± 0.022	6.426LeuVal: 6.426 ± 0.028	1.168LeuTrp: 1.168 ± 0.011	2.559LeuTyr: 2.559 ± 0.015	0.0LeuXaa: 0.0 ± 0.0
Met	2.005MetAla: 2.005 ± 0.014	0.346MetCys: 0.346 ± 0.006	1.346MetAsp: 1.346 ± 0.012	1.953MetGlu: 1.953 ± 0.014	0.855MetPhe: 0.855 ± 0.01	1.578MetGly: 1.578 ± 0.013	0.571MetHis: 0.571 ± 0.007	1.188MetIle: 1.188 ± 0.012	1.709MetLys: 1.709 ± 0.013	2.196MetLeu: 2.196 ± 0.014	0.694MetMet: 0.694 ± 0.008	1.062MetAsn: 1.062 ± 0.01	1.015MetPro: 1.015 ± 0.01	0.951MetGln: 0.951 ± 0.012	1.184MetArg: 1.184 ± 0.01	1.789MetSer: 1.789 ± 0.013	1.045MetThr: 1.045 ± 0.011	1.656MetVal: 1.656 ± 0.013	0.276MetTrp: 0.276 ± 0.004	0.592MetTyr: 0.592 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	2.719AsnAla: 2.719 ± 0.017	0.903AsnCys: 0.903 ± 0.009	2.15AsnAsp: 2.15 ± 0.018	2.564AsnGlu: 2.564 ± 0.019	2.075AsnPhe: 2.075 ± 0.014	3.229AsnGly: 3.229 ± 0.021	1.249AsnHis: 1.249 ± 0.011	2.599AsnIle: 2.599 ± 0.018	2.488AsnLys: 2.488 ± 0.017	4.789AsnLeu: 4.789 ± 0.029	1.164AsnMet: 1.164 ± 0.01	2.531AsnAsn: 2.531 ± 0.032	2.358AsnPro: 2.358 ± 0.015	1.711AsnGln: 1.711 ± 0.015	2.072AsnArg: 2.072 ± 0.016	4.112AsnSer: 4.112 ± 0.022	2.162AsnThr: 2.162 ± 0.014	2.935AsnVal: 2.935 ± 0.02	0.586AsnTrp: 0.586 ± 0.008	1.351AsnTyr: 1.351 ± 0.013	0.0AsnXaa: 0.0 ± 0.0
Pro	2.812ProAla: 2.812 ± 0.024	0.809ProCys: 0.809 ± 0.01	2.327ProAsp: 2.327 ± 0.016	2.93ProGlu: 2.93 ± 0.018	2.211ProPhe: 2.211 ± 0.014	2.516ProGly: 2.516 ± 0.018	1.249ProHis: 1.249 ± 0.014	2.282ProIle: 2.282 ± 0.015	2.748ProLys: 2.748 ± 0.019	4.548ProLeu: 4.548 ± 0.024	0.937ProMet: 0.937 ± 0.008	2.424ProAsn: 2.424 ± 0.018	3.972ProPro: 3.972 ± 0.059	1.883ProGln: 1.883 ± 0.016	2.372ProArg: 2.372 ± 0.016	5.422ProSer: 5.422 ± 0.03	2.701ProThr: 2.701 ± 0.018	2.993ProVal: 2.993 ± 0.02	0.601ProTrp: 0.601 ± 0.007	1.327ProTyr: 1.327 ± 0.014	0.0ProXaa: 0.0 ± 0.0
Gln	2.223GlnAla: 2.223 ± 0.016	0.621GlnCys: 0.621 ± 0.008	1.612GlnAsp: 1.612 ± 0.013	2.32GlnGlu: 2.32 ± 0.015	1.433GlnPhe: 1.433 ± 0.012	2.038GlnGly: 2.038 ± 0.014	1.046GlnHis: 1.046 ± 0.012	2.064GlnIle: 2.064 ± 0.013	2.358GlnLys: 2.358 ± 0.016	3.642GlnLeu: 3.642 ± 0.021	0.974GlnMet: 0.974 ± 0.009	1.925GlnAsn: 1.925 ± 0.016	1.805GlnPro: 1.805 ± 0.016	2.066GlnGln: 2.066 ± 0.029	2.127GlnArg: 2.127 ± 0.015	2.884GlnSer: 2.884 ± 0.019	1.825GlnThr: 1.825 ± 0.014	2.289GlnVal: 2.289 ± 0.015	0.464GlnTrp: 0.464 ± 0.008	0.943GlnTyr: 0.943 ± 0.011	0.0GlnXaa: 0.0 ± 0.0
Arg	3.092ArgAla: 3.092 ± 0.018	0.986ArgCys: 0.986 ± 0.009	2.612ArgAsp: 2.612 ± 0.018	3.376ArgGlu: 3.376 ± 0.018	2.243ArgPhe: 2.243 ± 0.013	3.156ArgGly: 3.156 ± 0.022	1.345ArgHis: 1.345 ± 0.012	2.804ArgIle: 2.804 ± 0.016	3.819ArgLys: 3.819 ± 0.02	4.893ArgLeu: 4.893 ± 0.022	1.309ArgMet: 1.309 ± 0.01	2.513ArgAsn: 2.513 ± 0.017	2.273ArgPro: 2.273 ± 0.017	1.803ArgGln: 1.803 ± 0.012	3.869ArgArg: 3.869 ± 0.024	4.311ArgSer: 4.311 ± 0.027	2.511ArgThr: 2.511 ± 0.016	3.413ArgVal: 3.413 ± 0.018	0.744ArgTrp: 0.744 ± 0.01	1.414ArgTyr: 1.414 ± 0.012	0.0ArgXaa: 0.0 ± 0.0
Ser	5.312SerAla: 5.312 ± 0.022	1.758SerCys: 1.758 ± 0.015	4.426SerAsp: 4.426 ± 0.023	4.88SerGlu: 4.88 ± 0.024	4.285SerPhe: 4.285 ± 0.022	5.79SerGly: 5.79 ± 0.03	2.276SerHis: 2.276 ± 0.016	4.572SerIle: 4.572 ± 0.021	5.009SerLys: 5.009 ± 0.024	9.056SerLeu: 9.056 ± 0.037	2.102SerMet: 2.102 ± 0.017	4.327SerAsn: 4.327 ± 0.025	4.652SerPro: 4.652 ± 0.035	3.109SerGln: 3.109 ± 0.019	4.381SerArg: 4.381 ± 0.024	11.142SerSer: 11.142 ± 0.055	4.794SerThr: 4.794 ± 0.024	5.498SerVal: 5.498 ± 0.025	1.192SerTrp: 1.192 ± 0.011	2.375SerTyr: 2.375 ± 0.016	0.0SerXaa: 0.0 ± 0.0
Thr	3.357ThrAla: 3.357 ± 0.02	0.98ThrCys: 0.98 ± 0.011	2.228ThrAsp: 2.228 ± 0.016	2.795ThrGlu: 2.795 ± 0.019	2.232ThrPhe: 2.232 ± 0.015	3.161ThrGly: 3.161 ± 0.017	1.173ThrHis: 1.173 ± 0.011	2.756ThrIle: 2.756 ± 0.018	2.798ThrLys: 2.798 ± 0.017	5.013ThrLeu: 5.013 ± 0.022	1.214ThrMet: 1.214 ± 0.012	2.233ThrAsn: 2.233 ± 0.016	2.711ThrPro: 2.711 ± 0.021	1.631ThrGln: 1.631 ± 0.013	2.399ThrArg: 2.399 ± 0.014	4.666ThrSer: 4.666 ± 0.022	3.174ThrThr: 3.174 ± 0.023	3.493ThrVal: 3.493 ± 0.018	0.65ThrTrp: 0.65 ± 0.008	1.392ThrTyr: 1.392 ± 0.012	0.0ThrXaa: 0.0 ± 0.0
Val	4.836ValAla: 4.836 ± 0.025	1.236ValCys: 1.236 ± 0.021	3.65ValAsp: 3.65 ± 0.022	4.446ValGlu: 4.446 ± 0.022	2.876ValPhe: 2.876 ± 0.018	4.153ValGly: 4.153 ± 0.021	1.581ValHis: 1.581 ± 0.015	3.421ValIle: 3.421 ± 0.02	3.953ValLys: 3.953 ± 0.022	6.449ValLeu: 6.449 ± 0.03	1.546ValMet: 1.546 ± 0.013	2.694ValAsn: 2.694 ± 0.018	3.23ValPro: 3.23 ± 0.019	2.333ValGln: 2.333 ± 0.015	3.114ValArg: 3.114 ± 0.018	5.625ValSer: 5.625 ± 0.025	3.364ValThr: 3.364 ± 0.016	5.125ValVal: 5.125 ± 0.027	0.787ValTrp: 0.787 ± 0.008	1.926ValTyr: 1.926 ± 0.014	0.0ValXaa: 0.0 ± 0.0
Trp	0.718TrpAla: 0.718 ± 0.009	0.26TrpCys: 0.26 ± 0.005	0.675TrpAsp: 0.675 ± 0.008	0.751TrpGlu: 0.751 ± 0.008	0.576TrpPhe: 0.576 ± 0.008	0.733TrpGly: 0.733 ± 0.009	0.306TrpHis: 0.306 ± 0.006	0.696TrpIle: 0.696 ± 0.008	0.978TrpLys: 0.978 ± 0.011	1.252TrpLeu: 1.252 ± 0.011	0.345TrpMet: 0.345 ± 0.005	0.741TrpAsn: 0.741 ± 0.009	0.493TrpPro: 0.493 ± 0.007	0.449TrpGln: 0.449 ± 0.007	0.813TrpArg: 0.813 ± 0.009	1.003TrpSer: 1.003 ± 0.01	0.664TrpThr: 0.664 ± 0.008	0.797TrpVal: 0.797 ± 0.01	0.259TrpTrp: 0.259 ± 0.005	0.347TrpTyr: 0.347 ± 0.006	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.784TyrAla: 1.784 ± 0.016	0.646TyrCys: 0.646 ± 0.008	1.532TyrAsp: 1.532 ± 0.012	1.579TyrGlu: 1.579 ± 0.012	1.33TyrPhe: 1.33 ± 0.012	2.083TyrGly: 2.083 ± 0.019	0.747TyrHis: 0.747 ± 0.008	1.459TyrIle: 1.459 ± 0.012	1.528TyrLys: 1.528 ± 0.013	2.757TyrLeu: 2.757 ± 0.018	0.721TyrMet: 0.721 ± 0.009	1.328TyrAsn: 1.328 ± 0.015	1.275TyrPro: 1.275 ± 0.013	0.933TyrGln: 0.933 ± 0.009	1.428TyrArg: 1.428 ± 0.012	2.296TyrSer: 2.296 ± 0.016	1.311TyrThr: 1.311 ± 0.009	1.794TyrVal: 1.794 ± 0.014	0.4TyrTrp: 0.4 ± 0.006	0.985TyrTyr: 0.985 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 30270 proteins (11002619 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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