Amino acid dipepetide frequency for Gemycircularvirus gemy-ch-rat1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.168AlaAla: 5.168 ± 1.746
0.0AlaCys: 0.0 ± 0.0
7.752AlaAsp: 7.752 ± 3.694
7.752AlaGlu: 7.752 ± 2.173
0.0AlaPhe: 0.0 ± 0.0
3.876AlaGly: 3.876 ± 2.534
0.0AlaHis: 0.0 ± 0.0
2.584AlaIle: 2.584 ± 0.848
1.292AlaLys: 1.292 ± 0.953
6.46AlaLeu: 6.46 ± 1.396
3.876AlaMet: 3.876 ± 0.482
2.584AlaAsn: 2.584 ± 1.906
2.584AlaPro: 2.584 ± 0.848
2.584AlaGln: 2.584 ± 1.69
7.752AlaArg: 7.752 ± 3.694
3.876AlaSer: 3.876 ± 0.482
7.752AlaThr: 7.752 ± 2.627
3.876AlaVal: 3.876 ± 0.482
0.0AlaTrp: 0.0 ± 0.0
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
2.584CysAla: 2.584 ± 0.848
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
1.292CysPhe: 1.292 ± 0.953
1.292CysGly: 1.292 ± 0.845
1.292CysHis: 1.292 ± 0.845
3.876CysIle: 3.876 ± 1.399
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
1.292CysAsn: 1.292 ± 0.845
1.292CysPro: 1.292 ± 0.953
0.0CysGln: 0.0 ± 0.0
3.876CysArg: 3.876 ± 2.534
1.292CysSer: 1.292 ± 1.285
1.292CysThr: 1.292 ± 0.845
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.292AspAla: 1.292 ± 0.845
0.0AspCys: 0.0 ± 0.0
1.292AspAsp: 1.292 ± 0.953
1.292AspGlu: 1.292 ± 0.953
2.584AspPhe: 2.584 ± 1.094
5.168AspGly: 5.168 ± 2.15
1.292AspHis: 1.292 ± 1.285
0.0AspIle: 0.0 ± 0.0
5.168AspLys: 5.168 ± 1.696
6.46AspLeu: 6.46 ± 1.712
0.0AspMet: 0.0 ± 0.982
0.0AspAsn: 0.0 ± 0.0
1.292AspPro: 1.292 ± 0.845
2.584AspGln: 2.584 ± 0.848
2.584AspArg: 2.584 ± 1.094
2.584AspSer: 2.584 ± 2.57
3.876AspThr: 3.876 ± 2.859
6.46AspVal: 6.46 ± 2.154
2.584AspTrp: 2.584 ± 0.848
2.584AspTyr: 2.584 ± 0.848
0.0AspXaa: 0.0 ± 0.0
Glu
2.584GluAla: 2.584 ± 1.094
1.292GluCys: 1.292 ± 0.845
2.584GluAsp: 2.584 ± 1.261
2.584GluGlu: 2.584 ± 1.094
2.584GluPhe: 2.584 ± 1.094
1.292GluGly: 1.292 ± 1.285
1.292GluHis: 1.292 ± 0.845
0.0GluIle: 0.0 ± 0.0
3.876GluLys: 3.876 ± 1.594
3.876GluLeu: 3.876 ± 1.473
0.0GluMet: 0.0 ± 0.0
6.46GluAsn: 6.46 ± 1.341
1.292GluPro: 1.292 ± 0.845
0.0GluGln: 0.0 ± 0.0
7.752GluArg: 7.752 ± 2.87
7.752GluSer: 7.752 ± 1.509
1.292GluThr: 1.292 ± 0.845
1.292GluVal: 1.292 ± 1.285
0.0GluTrp: 0.0 ± 0.0
2.584GluTyr: 2.584 ± 1.094
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
1.292PheCys: 1.292 ± 0.953
2.584PheAsp: 2.584 ± 1.69
0.0PheGlu: 0.0 ± 0.0
3.876PhePhe: 3.876 ± 1.594
3.876PheGly: 3.876 ± 1.473
3.876PheHis: 3.876 ± 2.534
1.292PheIle: 1.292 ± 0.953
1.292PheLys: 1.292 ± 0.953
1.292PheLeu: 1.292 ± 1.285
0.0PheMet: 0.0 ± 0.0
2.584PheAsn: 2.584 ± 1.906
1.292PhePro: 1.292 ± 0.845
2.584PheGln: 2.584 ± 0.848
0.0PheArg: 0.0 ± 0.0
6.46PheSer: 6.46 ± 0.5
1.292PheThr: 1.292 ± 1.285
2.584PheVal: 2.584 ± 1.094
2.584PheTrp: 2.584 ± 0.848
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
9.044GlyAla: 9.044 ± 1.307
2.584GlyCys: 2.584 ± 1.094
5.168GlyAsp: 5.168 ± 1.746
5.168GlyGlu: 5.168 ± 0.549
3.876GlyPhe: 3.876 ± 1.829
11.628GlyGly: 11.628 ± 3.784
0.0GlyHis: 0.0 ± 0.0
5.168GlyIle: 5.168 ± 2.15
1.292GlyLys: 1.292 ± 0.845
11.628GlyLeu: 11.628 ± 4.851
2.584GlyMet: 2.584 ± 0.848
2.584GlyAsn: 2.584 ± 0.848
3.876GlyPro: 3.876 ± 1.594
2.584GlyGln: 2.584 ± 0.848
6.46GlyArg: 6.46 ± 2.897
10.336GlySer: 10.336 ± 1.779
2.584GlyThr: 2.584 ± 0.848
1.292GlyVal: 1.292 ± 0.845
0.0GlyTrp: 0.0 ± 0.0
3.876GlyTyr: 3.876 ± 1.399
0.0GlyXaa: 0.0 ± 0.0
His
3.876HisAla: 3.876 ± 2.534
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.292HisGlu: 1.292 ± 0.845
1.292HisPhe: 1.292 ± 0.845
2.584HisGly: 2.584 ± 1.69
0.0HisHis: 0.0 ± 0.0
1.292HisIle: 1.292 ± 0.845
0.0HisLys: 0.0 ± 0.0
1.292HisLeu: 1.292 ± 0.845
0.0HisMet: 0.0 ± 0.0
1.292HisAsn: 1.292 ± 1.285
1.292HisPro: 1.292 ± 0.845
0.0HisGln: 0.0 ± 0.0
2.584HisArg: 2.584 ± 0.848
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
1.292HisVal: 1.292 ± 0.845
1.292HisTrp: 1.292 ± 1.285
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.292IleAla: 1.292 ± 0.845
1.292IleCys: 1.292 ± 0.953
0.0IleAsp: 0.0 ± 0.0
2.584IleGlu: 2.584 ± 1.261
2.584IlePhe: 2.584 ± 0.848
2.584IleGly: 2.584 ± 0.848
1.292IleHis: 1.292 ± 0.845
0.0IleIle: 0.0 ± 0.0
2.584IleLys: 2.584 ± 1.69
2.584IleLeu: 2.584 ± 1.906
0.0IleMet: 0.0 ± 0.0
1.292IleAsn: 1.292 ± 0.953
1.292IlePro: 1.292 ± 0.845
3.876IleGln: 3.876 ± 1.594
2.584IleArg: 2.584 ± 1.906
3.876IleSer: 3.876 ± 0.482
5.168IleThr: 5.168 ± 2.15
3.876IleVal: 3.876 ± 1.594
1.292IleTrp: 1.292 ± 0.845
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
1.292LysAla: 1.292 ± 0.845
2.584LysCys: 2.584 ± 0.848
1.292LysAsp: 1.292 ± 0.845
2.584LysGlu: 2.584 ± 1.69
0.0LysPhe: 0.0 ± 0.0
3.876LysGly: 3.876 ± 1.399
0.0LysHis: 0.0 ± 0.0
2.584LysIle: 2.584 ± 1.906
1.292LysLys: 1.292 ± 0.953
0.0LysLeu: 0.0 ± 0.0
3.876LysMet: 3.876 ± 1.594
3.876LysAsn: 3.876 ± 1.594
1.292LysPro: 1.292 ± 0.845
1.292LysGln: 1.292 ± 0.953
1.292LysArg: 1.292 ± 0.953
5.168LysSer: 5.168 ± 1.696
1.292LysThr: 1.292 ± 0.845
1.292LysVal: 1.292 ± 0.845
0.0LysTrp: 0.0 ± 0.0
1.292LysTyr: 1.292 ± 0.953
0.0LysXaa: 0.0 ± 0.0
Leu
5.168LeuAla: 5.168 ± 2.137
2.584LeuCys: 2.584 ± 0.848
5.168LeuAsp: 5.168 ± 1.746
3.876LeuGlu: 3.876 ± 2.232
3.876LeuPhe: 3.876 ± 1.399
5.168LeuGly: 5.168 ± 2.188
0.0LeuHis: 0.0 ± 0.0
2.584LeuIle: 2.584 ± 0.848
2.584LeuLys: 2.584 ± 0.848
1.292LeuLeu: 1.292 ± 1.285
3.876LeuMet: 3.876 ± 2.306
2.584LeuAsn: 2.584 ± 1.906
2.584LeuPro: 2.584 ± 1.261
6.46LeuGln: 6.46 ± 3.561
2.584LeuArg: 2.584 ± 2.57
7.752LeuSer: 7.752 ± 4.464
7.752LeuThr: 7.752 ± 3.783
7.752LeuVal: 7.752 ± 0.963
5.168LeuTrp: 5.168 ± 1.746
2.584LeuTyr: 2.584 ± 1.69
0.0LeuXaa: 0.0 ± 0.0
Met
2.584MetAla: 2.584 ± 1.094
0.0MetCys: 0.0 ± 0.0
1.292MetAsp: 1.292 ± 0.953
2.584MetGlu: 2.584 ± 1.261
1.292MetPhe: 1.292 ± 1.285
1.292MetGly: 1.292 ± 1.285
1.292MetHis: 1.292 ± 1.285
1.292MetIle: 1.292 ± 0.845
1.292MetLys: 1.292 ± 0.953
1.292MetLeu: 1.292 ± 0.953
0.0MetMet: 0.0 ± 0.0
3.876MetAsn: 3.876 ± 0.482
2.584MetPro: 2.584 ± 1.094
1.292MetGln: 1.292 ± 0.845
2.584MetArg: 2.584 ± 0.848
2.584MetSer: 2.584 ± 1.261
1.292MetThr: 1.292 ± 0.953
0.0MetVal: 0.0 ± 0.0
2.584MetTrp: 2.584 ± 2.57
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
5.168AsnAla: 5.168 ± 1.696
1.292AsnCys: 1.292 ± 0.845
1.292AsnAsp: 1.292 ± 0.953
0.0AsnGlu: 0.0 ± 0.0
2.584AsnPhe: 2.584 ± 1.094
5.168AsnGly: 5.168 ± 2.63
1.292AsnHis: 1.292 ± 0.845
3.876AsnIle: 3.876 ± 1.399
2.584AsnLys: 2.584 ± 1.906
2.584AsnLeu: 2.584 ± 1.906
1.292AsnMet: 1.292 ± 1.285
1.292AsnAsn: 1.292 ± 0.953
1.292AsnPro: 1.292 ± 1.285
1.292AsnGln: 1.292 ± 0.953
1.292AsnArg: 1.292 ± 0.845
3.876AsnSer: 3.876 ± 2.859
3.876AsnThr: 3.876 ± 2.859
5.168AsnVal: 5.168 ± 0.549
2.584AsnTrp: 2.584 ± 1.69
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
1.292ProAla: 1.292 ± 0.953
1.292ProCys: 1.292 ± 0.845
1.292ProAsp: 1.292 ± 0.845
2.584ProGlu: 2.584 ± 1.69
0.0ProPhe: 0.0 ± 0.0
2.584ProGly: 2.584 ± 1.906
0.0ProHis: 0.0 ± 0.0
1.292ProIle: 1.292 ± 0.845
1.292ProLys: 1.292 ± 0.845
3.876ProLeu: 3.876 ± 0.482
3.876ProMet: 3.876 ± 2.361
2.584ProAsn: 2.584 ± 0.848
1.292ProPro: 1.292 ± 1.285
0.0ProGln: 0.0 ± 0.0
2.584ProArg: 2.584 ± 1.69
3.876ProSer: 3.876 ± 1.473
3.876ProThr: 3.876 ± 1.829
1.292ProVal: 1.292 ± 0.953
2.584ProTrp: 2.584 ± 0.848
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
1.292GlnCys: 1.292 ± 0.845
2.584GlnAsp: 2.584 ± 0.848
3.876GlnGlu: 3.876 ± 2.361
1.292GlnPhe: 1.292 ± 0.845
1.292GlnGly: 1.292 ± 0.845
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
1.292GlnLys: 1.292 ± 0.845
2.584GlnLeu: 2.584 ± 1.261
1.292GlnMet: 1.292 ± 0.845
1.292GlnAsn: 1.292 ± 1.285
1.292GlnPro: 1.292 ± 0.953
0.0GlnGln: 0.0 ± 0.0
5.168GlnArg: 5.168 ± 5.141
5.168GlnSer: 5.168 ± 2.486
3.876GlnThr: 3.876 ± 1.829
2.584GlnVal: 2.584 ± 0.848
0.0GlnTrp: 0.0 ± 0.0
1.292GlnTyr: 1.292 ± 0.953
0.0GlnXaa: 0.0 ± 0.0
Arg
5.168ArgAla: 5.168 ± 2.188
0.0ArgCys: 0.0 ± 0.0
0.0ArgAsp: 0.0 ± 0.0
2.584ArgGlu: 2.584 ± 1.094
2.584ArgPhe: 2.584 ± 1.69
2.584ArgGly: 2.584 ± 1.906
2.584ArgHis: 2.584 ± 1.69
5.168ArgIle: 5.168 ± 1.041
5.168ArgLys: 5.168 ± 1.696
7.752ArgLeu: 7.752 ± 4.312
1.292ArgMet: 1.292 ± 1.285
5.168ArgAsn: 5.168 ± 1.696
2.584ArgPro: 2.584 ± 1.69
2.584ArgGln: 2.584 ± 1.094
3.876ArgArg: 3.876 ± 0.482
7.752ArgSer: 7.752 ± 2.173
1.292ArgThr: 1.292 ± 1.285
2.584ArgVal: 2.584 ± 0.848
1.292ArgTrp: 1.292 ± 1.285
5.168ArgTyr: 5.168 ± 0.549
0.0ArgXaa: 0.0 ± 0.0
Ser
3.876SerAla: 3.876 ± 3.856
1.292SerCys: 1.292 ± 0.845
1.292SerAsp: 1.292 ± 0.953
3.876SerGlu: 3.876 ± 1.594
1.292SerPhe: 1.292 ± 0.845
20.672SerGly: 20.672 ± 0.99
2.584SerHis: 2.584 ± 1.69
5.168SerIle: 5.168 ± 2.63
0.0SerLys: 0.0 ± 0.0
7.752SerLeu: 7.752 ± 2.945
1.292SerMet: 1.292 ± 1.285
6.46SerAsn: 6.46 ± 0.5
1.292SerPro: 1.292 ± 1.285
2.584SerGln: 2.584 ± 2.57
5.168SerArg: 5.168 ± 0.549
9.044SerSer: 9.044 ± 4.066
11.628SerThr: 11.628 ± 2.525
9.044SerVal: 9.044 ± 2.854
1.292SerTrp: 1.292 ± 1.285
2.584SerTyr: 2.584 ± 0.848
0.0SerXaa: 0.0 ± 0.0
Thr
5.168ThrAla: 5.168 ± 2.63
0.0ThrCys: 0.0 ± 0.0
3.876ThrAsp: 3.876 ± 2.859
1.292ThrGlu: 1.292 ± 0.845
1.292ThrPhe: 1.292 ± 0.953
5.168ThrGly: 5.168 ± 2.522
2.584ThrHis: 2.584 ± 0.848
2.584ThrIle: 2.584 ± 0.848
0.0ThrLys: 0.0 ± 0.0
6.46ThrLeu: 6.46 ± 4.74
2.584ThrMet: 2.584 ± 0.848
1.292ThrAsn: 1.292 ± 0.953
5.168ThrPro: 5.168 ± 2.486
3.876ThrGln: 3.876 ± 2.361
3.876ThrArg: 3.876 ± 0.482
11.628ThrSer: 11.628 ± 3.964
6.46ThrThr: 6.46 ± 2.994
2.584ThrVal: 2.584 ± 1.69
1.292ThrTrp: 1.292 ± 0.845
2.584ThrTyr: 2.584 ± 1.094
0.0ThrXaa: 0.0 ± 0.0
Val
2.584ValAla: 2.584 ± 1.094
2.584ValCys: 2.584 ± 1.69
9.044ValAsp: 9.044 ± 3.182
3.876ValGlu: 3.876 ± 0.482
3.876ValPhe: 3.876 ± 1.399
6.46ValGly: 6.46 ± 2.897
0.0ValHis: 0.0 ± 0.0
0.0ValIle: 0.0 ± 0.0
2.584ValLys: 2.584 ± 0.848
7.752ValLeu: 7.752 ± 2.87
1.292ValMet: 1.292 ± 0.724
1.292ValAsn: 1.292 ± 0.953
1.292ValPro: 1.292 ± 1.285
0.0ValGln: 0.0 ± 0.0
1.292ValArg: 1.292 ± 1.285
2.584ValSer: 2.584 ± 1.906
3.876ValThr: 3.876 ± 0.482
5.168ValVal: 5.168 ± 3.379
3.876ValTrp: 3.876 ± 1.473
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
3.876TrpAla: 3.876 ± 2.534
0.0TrpCys: 0.0 ± 0.0
2.584TrpAsp: 2.584 ± 2.57
2.584TrpGlu: 2.584 ± 1.094
2.584TrpPhe: 2.584 ± 1.906
2.584TrpGly: 2.584 ± 1.094
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.292TrpLys: 1.292 ± 0.845
5.168TrpLeu: 5.168 ± 2.137
1.292TrpMet: 1.292 ± 1.285
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.292TrpGln: 1.292 ± 1.285
2.584TrpArg: 2.584 ± 0.848
1.292TrpSer: 1.292 ± 1.285
1.292TrpThr: 1.292 ± 0.953
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.292TrpTyr: 1.292 ± 0.953
0.0TrpXaa: 0.0 ± 0.0
Tyr
7.752TyrAla: 7.752 ± 3.773
0.0TyrCys: 0.0 ± 0.0
1.292TyrAsp: 1.292 ± 0.845
0.0TyrGlu: 0.0 ± 0.0
0.0TyrPhe: 0.0 ± 0.0
2.584TyrGly: 2.584 ± 1.094
0.0TyrHis: 0.0 ± 0.0
1.292TyrIle: 1.292 ± 0.953
1.292TyrLys: 1.292 ± 0.845
1.292TyrLeu: 1.292 ± 1.285
1.292TyrMet: 1.292 ± 0.953
0.0TyrAsn: 0.0 ± 0.0
2.584TyrPro: 2.584 ± 0.848
1.292TyrGln: 1.292 ± 0.953
1.292TyrArg: 1.292 ± 1.285
1.292TyrSer: 1.292 ± 0.845
0.0TyrThr: 0.0 ± 0.0
1.292TyrVal: 1.292 ± 0.953
1.292TyrTrp: 1.292 ± 0.953
1.292TyrTyr: 1.292 ± 0.953
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (775 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski