Amino acid dipepetide frequency for Beihai picorna-like virus 124

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.006AlaAla: 4.006 ± 2.101
0.401AlaCys: 0.401 ± 0.467
3.606AlaAsp: 3.606 ± 0.818
5.609AlaGlu: 5.609 ± 0.91
3.606AlaPhe: 3.606 ± 0.14
6.01AlaGly: 6.01 ± 1.798
2.003AlaHis: 2.003 ± 0.373
3.606AlaIle: 3.606 ± 1.214
2.404AlaLys: 2.404 ± 0.584
5.208AlaLeu: 5.208 ± 0.7
1.603AlaMet: 1.603 ± 0.163
3.606AlaAsn: 3.606 ± 0.818
2.003AlaPro: 2.003 ± 0.304
2.003AlaGln: 2.003 ± 0.304
3.606AlaArg: 3.606 ± 0.537
2.804AlaSer: 2.804 ± 0.794
4.006AlaThr: 4.006 ± 1.962
4.808AlaVal: 4.808 ± 2.522
0.401AlaTrp: 0.401 ± 0.467
4.808AlaTyr: 4.808 ± 0.187
0.0AlaXaa: 0.0 ± 0.0
Cys
1.202CysAla: 1.202 ± 0.047
0.0CysCys: 0.0 ± 0.0
1.202CysAsp: 1.202 ± 0.047
0.401CysGlu: 0.401 ± 0.21
0.801CysPhe: 0.801 ± 0.934
1.202CysGly: 1.202 ± 0.63
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.801CysLys: 0.801 ± 0.42
0.0CysLeu: 0.0 ± 0.0
0.401CysMet: 0.401 ± 0.21
0.401CysAsn: 0.401 ± 0.21
0.0CysPro: 0.0 ± 0.0
0.401CysGln: 0.401 ± 0.21
1.603CysArg: 1.603 ± 0.841
0.401CysSer: 0.401 ± 0.467
1.202CysThr: 1.202 ± 0.047
1.202CysVal: 1.202 ± 0.63
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.006AspAla: 4.006 ± 0.07
1.202AspCys: 1.202 ± 0.63
3.205AspAsp: 3.205 ± 0.327
3.606AspGlu: 3.606 ± 1.214
6.01AspPhe: 6.01 ± 1.588
3.205AspGly: 3.205 ± 1.004
1.202AspHis: 1.202 ± 1.401
3.205AspIle: 3.205 ± 1.681
3.606AspLys: 3.606 ± 1.214
5.609AspLeu: 5.609 ± 0.91
1.202AspMet: 1.202 ± 1.401
1.202AspAsn: 1.202 ± 0.724
2.804AspPro: 2.804 ± 0.794
1.202AspGln: 1.202 ± 0.047
2.804AspArg: 2.804 ± 0.794
3.606AspSer: 3.606 ± 1.495
5.208AspThr: 5.208 ± 0.654
7.612AspVal: 7.612 ± 0.607
0.0AspTrp: 0.0 ± 0.0
2.404AspTyr: 2.404 ± 0.094
0.0AspXaa: 0.0 ± 0.0
Glu
3.606GluAla: 3.606 ± 0.537
0.401GluCys: 0.401 ± 0.21
2.804GluAsp: 2.804 ± 0.117
4.006GluGlu: 4.006 ± 1.424
1.603GluPhe: 1.603 ± 0.841
2.804GluGly: 2.804 ± 0.794
1.202GluHis: 1.202 ± 0.63
2.404GluIle: 2.404 ± 0.771
3.205GluLys: 3.205 ± 1.681
6.01GluLeu: 6.01 ± 1.12
3.205GluMet: 3.205 ± 1.004
3.205GluAsn: 3.205 ± 0.327
1.202GluPro: 1.202 ± 0.047
0.801GluGln: 0.801 ± 0.42
3.205GluArg: 3.205 ± 0.327
2.804GluSer: 2.804 ± 0.117
2.804GluThr: 2.804 ± 2.592
4.808GluVal: 4.808 ± 1.844
0.801GluTrp: 0.801 ± 0.257
1.202GluTyr: 1.202 ± 0.724
0.0GluXaa: 0.0 ± 0.0
Phe
0.801PheAla: 0.801 ± 0.257
0.401PheCys: 0.401 ± 0.21
3.606PheAsp: 3.606 ± 0.14
2.003PheGlu: 2.003 ± 1.051
0.401PhePhe: 0.401 ± 0.21
2.003PheGly: 2.003 ± 0.304
0.801PheHis: 0.801 ± 0.934
0.801PheIle: 0.801 ± 0.257
2.804PheLys: 2.804 ± 0.794
3.606PheLeu: 3.606 ± 1.495
3.205PheMet: 3.205 ± 0.327
1.603PheAsn: 1.603 ± 0.841
2.404PhePro: 2.404 ± 0.584
1.603PheGln: 1.603 ± 0.163
4.407PheArg: 4.407 ± 1.075
2.804PheSer: 2.804 ± 0.561
3.606PheThr: 3.606 ± 0.818
2.804PheVal: 2.804 ± 0.561
0.401PheTrp: 0.401 ± 0.21
2.804PheTyr: 2.804 ± 0.117
0.0PheXaa: 0.0 ± 0.0
Gly
3.606GlyAla: 3.606 ± 0.537
0.801GlyCys: 0.801 ± 0.42
5.609GlyAsp: 5.609 ± 0.233
4.407GlyGlu: 4.407 ± 0.28
2.404GlyPhe: 2.404 ± 0.094
2.804GlyGly: 2.804 ± 0.561
0.401GlyHis: 0.401 ± 0.21
3.606GlyIle: 3.606 ± 1.214
4.808GlyLys: 4.808 ± 0.49
6.811GlyLeu: 6.811 ± 0.186
3.205GlyMet: 3.205 ± 0.351
4.006GlyAsn: 4.006 ± 1.962
2.804GlyPro: 2.804 ± 0.117
0.801GlyGln: 0.801 ± 0.257
2.804GlyArg: 2.804 ± 0.794
6.01GlySer: 6.01 ± 0.234
4.006GlyThr: 4.006 ± 0.607
4.808GlyVal: 4.808 ± 0.49
0.801GlyTrp: 0.801 ± 0.42
1.603GlyTyr: 1.603 ± 0.514
0.0GlyXaa: 0.0 ± 0.0
His
1.202HisAla: 1.202 ± 0.724
0.0HisCys: 0.0 ± 0.0
0.401HisAsp: 0.401 ± 0.21
0.801HisGlu: 0.801 ± 0.257
0.0HisPhe: 0.0 ± 0.0
1.202HisGly: 1.202 ± 0.047
0.0HisHis: 0.0 ± 0.0
0.401HisIle: 0.401 ± 0.21
1.202HisLys: 1.202 ± 0.047
3.205HisLeu: 3.205 ± 0.351
0.401HisMet: 0.401 ± 0.467
0.0HisAsn: 0.0 ± 0.0
0.801HisPro: 0.801 ± 0.42
0.0HisGln: 0.0 ± 0.0
2.003HisArg: 2.003 ± 0.373
0.401HisSer: 0.401 ± 0.21
1.603HisThr: 1.603 ± 0.514
3.205HisVal: 3.205 ± 0.327
0.401HisTrp: 0.401 ± 0.21
1.603HisTyr: 1.603 ± 0.163
0.0HisXaa: 0.0 ± 0.0
Ile
4.407IleAla: 4.407 ± 0.957
0.801IleCys: 0.801 ± 0.257
3.606IleAsp: 3.606 ± 0.818
2.404IleGlu: 2.404 ± 1.261
2.003IlePhe: 2.003 ± 1.051
1.202IleGly: 1.202 ± 0.047
1.603IleHis: 1.603 ± 0.841
1.603IleIle: 1.603 ± 0.841
2.804IleLys: 2.804 ± 0.561
4.006IleLeu: 4.006 ± 2.101
2.003IleMet: 2.003 ± 1.051
1.603IleAsn: 1.603 ± 0.514
3.205IlePro: 3.205 ± 1.028
2.003IleGln: 2.003 ± 0.304
2.003IleArg: 2.003 ± 0.304
4.006IleSer: 4.006 ± 0.07
3.606IleThr: 3.606 ± 0.537
3.205IleVal: 3.205 ± 0.327
0.401IleTrp: 0.401 ± 0.467
0.801IleTyr: 0.801 ± 0.257
0.0IleXaa: 0.0 ± 0.0
Lys
3.606LysAla: 3.606 ± 0.537
0.801LysCys: 0.801 ± 0.42
5.208LysAsp: 5.208 ± 1.377
3.606LysGlu: 3.606 ± 1.214
1.603LysPhe: 1.603 ± 0.163
3.205LysGly: 3.205 ± 0.327
0.801LysHis: 0.801 ± 0.257
3.205LysIle: 3.205 ± 1.681
4.006LysLys: 4.006 ± 0.747
2.404LysLeu: 2.404 ± 0.094
2.003LysMet: 2.003 ± 0.304
3.606LysAsn: 3.606 ± 1.214
3.205LysPro: 3.205 ± 0.351
1.202LysGln: 1.202 ± 0.047
2.003LysArg: 2.003 ± 1.051
4.006LysSer: 4.006 ± 0.07
4.808LysThr: 4.808 ± 0.187
5.208LysVal: 5.208 ± 0.7
1.202LysTrp: 1.202 ± 0.724
1.603LysTyr: 1.603 ± 0.163
0.0LysXaa: 0.0 ± 0.0
Leu
5.208LeuAla: 5.208 ± 1.377
1.202LeuCys: 1.202 ± 0.63
4.006LeuAsp: 4.006 ± 1.285
4.006LeuGlu: 4.006 ± 1.285
4.808LeuPhe: 4.808 ± 1.844
7.212LeuGly: 7.212 ± 0.281
0.801LeuHis: 0.801 ± 0.42
4.006LeuIle: 4.006 ± 1.424
6.01LeuLys: 6.01 ± 1.12
4.808LeuLeu: 4.808 ± 1.167
1.603LeuMet: 1.603 ± 0.163
4.407LeuAsn: 4.407 ± 0.397
4.407LeuPro: 4.407 ± 0.957
3.606LeuGln: 3.606 ± 0.14
3.205LeuArg: 3.205 ± 0.327
8.814LeuSer: 8.814 ± 0.117
7.212LeuThr: 7.212 ± 1.635
10.016LeuVal: 10.016 ± 0.842
0.401LeuTrp: 0.401 ± 0.21
2.804LeuTyr: 2.804 ± 0.117
0.0LeuXaa: 0.0 ± 0.0
Met
2.003MetAla: 2.003 ± 0.304
0.401MetCys: 0.401 ± 0.21
2.804MetAsp: 2.804 ± 0.561
2.804MetGlu: 2.804 ± 0.794
0.0MetPhe: 0.0 ± 0.0
2.003MetGly: 2.003 ± 0.304
0.401MetHis: 0.401 ± 0.467
1.603MetIle: 1.603 ± 0.841
2.804MetLys: 2.804 ± 0.117
3.205MetLeu: 3.205 ± 0.327
0.801MetMet: 0.801 ± 0.934
0.801MetAsn: 0.801 ± 0.257
2.003MetPro: 2.003 ± 0.373
1.603MetGln: 1.603 ± 0.514
2.404MetArg: 2.404 ± 0.584
1.603MetSer: 1.603 ± 1.191
1.202MetThr: 1.202 ± 0.63
3.205MetVal: 3.205 ± 0.351
0.0MetTrp: 0.0 ± 0.0
0.401MetTyr: 0.401 ± 0.21
0.0MetXaa: 0.0 ± 0.0
Asn
4.407AsnAla: 4.407 ± 0.957
0.401AsnCys: 0.401 ± 0.467
1.202AsnAsp: 1.202 ± 0.724
2.003AsnGlu: 2.003 ± 0.981
2.003AsnPhe: 2.003 ± 0.304
2.804AsnGly: 2.804 ± 1.238
0.401AsnHis: 0.401 ± 0.467
2.404AsnIle: 2.404 ± 0.771
2.404AsnLys: 2.404 ± 2.125
4.808AsnLeu: 4.808 ± 1.167
2.003AsnMet: 2.003 ± 0.981
3.606AsnAsn: 3.606 ± 0.14
3.205AsnPro: 3.205 ± 1.028
1.603AsnGln: 1.603 ± 0.163
2.003AsnArg: 2.003 ± 0.373
3.205AsnSer: 3.205 ± 1.028
4.006AsnThr: 4.006 ± 1.285
4.808AsnVal: 4.808 ± 0.187
0.401AsnTrp: 0.401 ± 0.21
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
2.804ProAla: 2.804 ± 1.238
0.401ProCys: 0.401 ± 0.21
2.804ProAsp: 2.804 ± 0.117
1.603ProGlu: 1.603 ± 0.841
3.205ProPhe: 3.205 ± 1.705
2.804ProGly: 2.804 ± 0.117
2.404ProHis: 2.404 ± 1.448
2.804ProIle: 2.804 ± 0.794
2.003ProLys: 2.003 ± 0.373
4.407ProLeu: 4.407 ± 0.397
1.603ProMet: 1.603 ± 0.514
2.003ProAsn: 2.003 ± 0.304
3.606ProPro: 3.606 ± 1.495
1.603ProGln: 1.603 ± 0.841
2.003ProArg: 2.003 ± 0.373
4.006ProSer: 4.006 ± 0.07
3.606ProThr: 3.606 ± 0.818
3.205ProVal: 3.205 ± 1.028
0.401ProTrp: 0.401 ± 0.21
1.603ProTyr: 1.603 ± 1.191
0.0ProXaa: 0.0 ± 0.0
Gln
1.603GlnAla: 1.603 ± 0.514
0.801GlnCys: 0.801 ± 0.257
0.801GlnAsp: 0.801 ± 0.257
2.404GlnGlu: 2.404 ± 1.448
0.401GlnPhe: 0.401 ± 0.467
2.404GlnGly: 2.404 ± 0.771
0.401GlnHis: 0.401 ± 0.21
1.603GlnIle: 1.603 ± 0.163
3.205GlnLys: 3.205 ± 1.004
3.606GlnLeu: 3.606 ± 0.537
0.801GlnMet: 0.801 ± 0.42
2.003GlnAsn: 2.003 ± 0.304
0.401GlnPro: 0.401 ± 0.21
0.401GlnGln: 0.401 ± 0.21
1.202GlnArg: 1.202 ± 0.63
1.603GlnSer: 1.603 ± 0.514
1.603GlnThr: 1.603 ± 0.514
0.801GlnVal: 0.801 ± 0.257
0.801GlnTrp: 0.801 ± 0.257
1.603GlnTyr: 1.603 ± 0.841
0.0GlnXaa: 0.0 ± 0.0
Arg
4.407ArgAla: 4.407 ± 0.28
0.401ArgCys: 0.401 ± 0.21
3.205ArgAsp: 3.205 ± 0.327
1.603ArgGlu: 1.603 ± 0.841
3.205ArgPhe: 3.205 ± 0.327
6.01ArgGly: 6.01 ± 0.234
1.603ArgHis: 1.603 ± 0.841
3.205ArgIle: 3.205 ± 1.028
1.603ArgLys: 1.603 ± 0.163
4.407ArgLeu: 4.407 ± 1.634
0.801ArgMet: 0.801 ± 0.42
1.603ArgAsn: 1.603 ± 0.163
2.804ArgPro: 2.804 ± 0.117
2.003ArgGln: 2.003 ± 0.304
4.407ArgArg: 4.407 ± 0.28
3.205ArgSer: 3.205 ± 0.327
2.404ArgThr: 2.404 ± 1.261
3.205ArgVal: 3.205 ± 1.004
0.401ArgTrp: 0.401 ± 0.21
2.804ArgTyr: 2.804 ± 0.561
0.0ArgXaa: 0.0 ± 0.0
Ser
2.404SerAla: 2.404 ± 0.094
0.401SerCys: 0.401 ± 0.21
6.811SerAsp: 6.811 ± 1.541
2.404SerGlu: 2.404 ± 0.584
2.003SerPhe: 2.003 ± 1.051
5.208SerGly: 5.208 ± 0.7
1.202SerHis: 1.202 ± 0.047
3.606SerIle: 3.606 ± 0.14
2.404SerLys: 2.404 ± 0.094
6.811SerLeu: 6.811 ± 1.845
1.603SerMet: 1.603 ± 0.514
4.407SerAsn: 4.407 ± 1.075
3.205SerPro: 3.205 ± 1.705
3.205SerGln: 3.205 ± 1.705
1.603SerArg: 1.603 ± 0.514
5.208SerSer: 5.208 ± 1.332
4.808SerThr: 4.808 ± 2.896
8.413SerVal: 8.413 ± 0.328
1.603SerTrp: 1.603 ± 0.514
2.003SerTyr: 2.003 ± 0.304
0.0SerXaa: 0.0 ± 0.0
Thr
4.006ThrAla: 4.006 ± 1.285
0.401ThrCys: 0.401 ± 0.21
4.006ThrAsp: 4.006 ± 1.285
2.804ThrGlu: 2.804 ± 0.561
3.205ThrPhe: 3.205 ± 1.028
2.804ThrGly: 2.804 ± 0.561
2.003ThrHis: 2.003 ± 0.373
4.407ThrIle: 4.407 ± 1.075
5.609ThrLys: 5.609 ± 0.233
5.208ThrLeu: 5.208 ± 0.654
2.404ThrMet: 2.404 ± 0.38
3.205ThrAsn: 3.205 ± 2.382
3.606ThrPro: 3.606 ± 1.495
0.401ThrGln: 0.401 ± 0.21
5.208ThrArg: 5.208 ± 0.023
4.808ThrSer: 4.808 ± 0.187
8.013ThrThr: 8.013 ± 0.538
6.01ThrVal: 6.01 ± 0.911
0.801ThrTrp: 0.801 ± 0.257
2.804ThrTyr: 2.804 ± 0.561
0.0ThrXaa: 0.0 ± 0.0
Val
9.215ValAla: 9.215 ± 2.802
1.202ValCys: 1.202 ± 0.047
5.609ValAsp: 5.609 ± 2.265
3.205ValGlu: 3.205 ± 0.351
3.205ValPhe: 3.205 ± 1.028
6.41ValGly: 6.41 ± 1.331
1.603ValHis: 1.603 ± 0.841
2.404ValIle: 2.404 ± 0.094
2.804ValLys: 2.804 ± 0.794
8.814ValLeu: 8.814 ± 2.591
1.603ValMet: 1.603 ± 0.749
4.006ValAsn: 4.006 ± 1.285
6.41ValPro: 6.41 ± 1.378
2.003ValGln: 2.003 ± 0.981
4.808ValArg: 4.808 ± 0.49
6.41ValSer: 6.41 ± 2.733
6.01ValThr: 6.01 ± 1.12
8.413ValVal: 8.413 ± 1.704
1.202ValTrp: 1.202 ± 0.047
3.205ValTyr: 3.205 ± 1.028
0.0ValXaa: 0.0 ± 0.0
Trp
1.202TrpAla: 1.202 ± 0.63
0.401TrpCys: 0.401 ± 0.21
0.401TrpAsp: 0.401 ± 0.21
0.401TrpGlu: 0.401 ± 0.21
0.401TrpPhe: 0.401 ± 0.21
0.801TrpGly: 0.801 ± 0.257
0.0TrpHis: 0.0 ± 0.0
0.401TrpIle: 0.401 ± 0.467
0.801TrpLys: 0.801 ± 0.257
0.801TrpLeu: 0.801 ± 0.257
0.401TrpMet: 0.401 ± 0.21
1.202TrpAsn: 1.202 ± 1.401
0.0TrpPro: 0.0 ± 0.0
0.401TrpGln: 0.401 ± 0.21
0.401TrpArg: 0.401 ± 0.21
1.202TrpSer: 1.202 ± 0.724
0.801TrpThr: 0.801 ± 0.934
1.202TrpVal: 1.202 ± 0.63
0.0TrpTrp: 0.0 ± 0.0
0.401TrpTyr: 0.401 ± 0.21
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.404TyrAla: 2.404 ± 0.094
0.401TyrCys: 0.401 ± 0.467
2.003TyrAsp: 2.003 ± 1.051
2.003TyrGlu: 2.003 ± 1.051
2.003TyrPhe: 2.003 ± 0.304
4.006TyrGly: 4.006 ± 1.285
0.0TyrHis: 0.0 ± 0.0
2.003TyrIle: 2.003 ± 0.981
2.003TyrLys: 2.003 ± 1.051
4.808TyrLeu: 4.808 ± 3.573
0.801TyrMet: 0.801 ± 0.257
1.202TyrAsn: 1.202 ± 0.047
0.801TyrPro: 0.801 ± 0.934
1.603TyrGln: 1.603 ± 0.841
1.603TyrArg: 1.603 ± 0.163
2.404TyrSer: 2.404 ± 0.094
1.603TyrThr: 1.603 ± 0.841
1.603TyrVal: 1.603 ± 0.514
1.202TyrTrp: 1.202 ± 0.047
0.801TyrTyr: 0.801 ± 0.934
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2497 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski