Amino acid dipepetide frequency for Fusobacterium necrophorum subsp. funduliforme 1_1_36S

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.411AlaAla: 4.411 ± 0.119	0.7AlaCys: 0.7 ± 0.039	2.619AlaAsp: 2.619 ± 0.062	4.235AlaGlu: 4.235 ± 0.083	3.066AlaPhe: 3.066 ± 0.078	4.557AlaGly: 4.557 ± 0.1	0.941AlaHis: 0.941 ± 0.035	5.155AlaIle: 5.155 ± 0.099	5.392AlaLys: 5.392 ± 0.104	6.258AlaLeu: 6.258 ± 0.118	1.871AlaMet: 1.871 ± 0.055	2.522AlaAsn: 2.522 ± 0.067	1.476AlaPro: 1.476 ± 0.047	1.606AlaGln: 1.606 ± 0.05	2.19AlaArg: 2.19 ± 0.051	3.483AlaSer: 3.483 ± 0.077	2.733AlaThr: 2.733 ± 0.08	4.223AlaVal: 4.223 ± 0.103	0.499AlaTrp: 0.499 ± 0.032	2.297AlaTyr: 2.297 ± 0.058	0.0AlaXaa: 0.0 ± 0.0
Cys	0.411CysAla: 0.411 ± 0.026	0.188CysCys: 0.188 ± 0.016	0.425CysAsp: 0.425 ± 0.028	0.585CysGlu: 0.585 ± 0.029	0.617CysPhe: 0.617 ± 0.031	0.867CysGly: 0.867 ± 0.044	0.253CysHis: 0.253 ± 0.02	0.937CysIle: 0.937 ± 0.036	0.675CysLys: 0.675 ± 0.027	0.953CysLeu: 0.953 ± 0.039	0.316CysMet: 0.316 ± 0.024	0.475CysAsn: 0.475 ± 0.027	0.451CysPro: 0.451 ± 0.029	0.338CysGln: 0.338 ± 0.02	0.435CysArg: 0.435 ± 0.026	0.694CysSer: 0.694 ± 0.038	0.393CysThr: 0.393 ± 0.024	0.518CysVal: 0.518 ± 0.026	0.063CysTrp: 0.063 ± 0.009	0.428CysTyr: 0.428 ± 0.025	0.0CysXaa: 0.0 ± 0.0
Asp	2.41AspAla: 2.41 ± 0.059	0.544AspCys: 0.544 ± 0.026	1.695AspAsp: 1.695 ± 0.059	3.252AspGlu: 3.252 ± 0.065	2.925AspPhe: 2.925 ± 0.072	3.054AspGly: 3.054 ± 0.097	0.571AspHis: 0.571 ± 0.029	4.625AspIle: 4.625 ± 0.077	3.6AspLys: 3.6 ± 0.074	4.463AspLeu: 4.463 ± 0.088	1.442AspMet: 1.442 ± 0.045	1.859AspAsn: 1.859 ± 0.059	1.312AspPro: 1.312 ± 0.045	0.831AspGln: 0.831 ± 0.036	1.91AspArg: 1.91 ± 0.061	2.915AspSer: 2.915 ± 0.065	2.288AspThr: 2.288 ± 0.058	2.864AspVal: 2.864 ± 0.057	0.489AspTrp: 0.489 ± 0.027	2.44AspTyr: 2.44 ± 0.075	0.0AspXaa: 0.0 ± 0.0
Glu	5.158GluAla: 5.158 ± 0.097	0.52GluCys: 0.52 ± 0.029	4.028GluAsp: 4.028 ± 0.086	10.157GluGlu: 10.157 ± 0.167	3.231GluPhe: 3.231 ± 0.07	4.469GluGly: 4.469 ± 0.08	1.369GluHis: 1.369 ± 0.05	7.846GluIle: 7.846 ± 0.118	10.157GluLys: 10.157 ± 0.167	6.937GluLeu: 6.937 ± 0.11	2.421GluMet: 2.421 ± 0.063	5.216GluAsn: 5.216 ± 0.091	1.257GluPro: 1.257 ± 0.05	2.602GluGln: 2.602 ± 0.063	3.712GluArg: 3.712 ± 0.082	3.417GluSer: 3.417 ± 0.081	3.576GluThr: 3.576 ± 0.076	5.216GluVal: 5.216 ± 0.083	0.602GluTrp: 0.602 ± 0.031	3.541GluTyr: 3.541 ± 0.08	0.0GluXaa: 0.0 ± 0.0
Phe	2.747PheAla: 2.747 ± 0.067	0.587PheCys: 0.587 ± 0.03	2.315PheAsp: 2.315 ± 0.062	3.211PheGlu: 3.211 ± 0.073	2.829PhePhe: 2.829 ± 0.082	3.323PheGly: 3.323 ± 0.075	1.163PheHis: 1.163 ± 0.045	3.615PheIle: 3.615 ± 0.085	2.61PheLys: 2.61 ± 0.058	5.69PheLeu: 5.69 ± 0.117	1.546PheMet: 1.546 ± 0.052	1.746PheAsn: 1.746 ± 0.048	1.656PhePro: 1.656 ± 0.056	2.267PheGln: 2.267 ± 0.055	1.939PheArg: 1.939 ± 0.057	4.166PheSer: 4.166 ± 0.077	2.145PheThr: 2.145 ± 0.057	2.958PheVal: 2.958 ± 0.07	0.471PheTrp: 0.471 ± 0.028	2.185PheTyr: 2.185 ± 0.058	0.0PheXaa: 0.0 ± 0.0
Gly	4.399GlyAla: 4.399 ± 0.11	0.654GlyCys: 0.654 ± 0.034	2.918GlyAsp: 2.918 ± 0.071	4.972GlyGlu: 4.972 ± 0.1	3.068GlyPhe: 3.068 ± 0.079	4.488GlyGly: 4.488 ± 0.093	1.01GlyHis: 1.01 ± 0.04	6.515GlyIle: 6.515 ± 0.111	6.825GlyLys: 6.825 ± 0.124	5.254GlyLeu: 5.254 ± 0.107	2.008GlyMet: 2.008 ± 0.059	3.472GlyAsn: 3.472 ± 0.08	1.096GlyPro: 1.096 ± 0.042	1.566GlyGln: 1.566 ± 0.057	2.769GlyArg: 2.769 ± 0.061	3.825GlySer: 3.825 ± 0.082	3.314GlyThr: 3.314 ± 0.077	4.568GlyVal: 4.568 ± 0.079	0.462GlyTrp: 0.462 ± 0.025	2.712GlyTyr: 2.712 ± 0.062	0.0GlyXaa: 0.0 ± 0.0
His	0.889HisAla: 0.889 ± 0.034	0.234HisCys: 0.234 ± 0.017	0.721HisAsp: 0.721 ± 0.03	1.049HisGlu: 1.049 ± 0.043	1.151HisPhe: 1.151 ± 0.043	1.215HisGly: 1.215 ± 0.044	0.46HisHis: 0.46 ± 0.033	1.518HisIle: 1.518 ± 0.047	1.195HisLys: 1.195 ± 0.039	1.835HisLeu: 1.835 ± 0.053	0.393HisMet: 0.393 ± 0.027	0.764HisAsn: 0.764 ± 0.032	0.749HisPro: 0.749 ± 0.031	0.639HisGln: 0.639 ± 0.03	0.775HisArg: 0.775 ± 0.037	1.233HisSer: 1.233 ± 0.044	0.827HisThr: 0.827 ± 0.033	0.828HisVal: 0.828 ± 0.039	0.171HisTrp: 0.171 ± 0.016	0.833HisTyr: 0.833 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	5.769IleAla: 5.769 ± 0.112	0.943IleCys: 0.943 ± 0.038	3.846IleAsp: 3.846 ± 0.083	6.222IleGlu: 6.222 ± 0.104	4.503IlePhe: 4.503 ± 0.1	5.559IleGly: 5.559 ± 0.106	1.639IleHis: 1.639 ± 0.051	5.966IleIle: 5.966 ± 0.114	5.695IleLys: 5.695 ± 0.097	9.614IleLeu: 9.614 ± 0.147	1.959IleMet: 1.959 ± 0.057	3.137IleAsn: 3.137 ± 0.079	3.374IlePro: 3.374 ± 0.071	3.581IleGln: 3.581 ± 0.076	3.42IleArg: 3.42 ± 0.073	6.086IleSer: 6.086 ± 0.104	3.989IleThr: 3.989 ± 0.079	5.169IleVal: 5.169 ± 0.09	0.609IleTrp: 0.609 ± 0.03	3.18IleTyr: 3.18 ± 0.073	0.0IleXaa: 0.0 ± 0.0
Lys	5.112LysAla: 5.112 ± 0.089	0.59LysCys: 0.59 ± 0.029	4.335LysAsp: 4.335 ± 0.091	9.672LysGlu: 9.672 ± 0.141	2.92LysPhe: 2.92 ± 0.062	4.668LysGly: 4.668 ± 0.089	1.393LysHis: 1.393 ± 0.045	8.392LysIle: 8.392 ± 0.121	9.264LysLys: 9.264 ± 0.139	6.915LysLeu: 6.915 ± 0.107	2.928LysMet: 2.928 ± 0.07	5.607LysAsn: 5.607 ± 0.108	1.685LysPro: 1.685 ± 0.049	3.048LysGln: 3.048 ± 0.076	3.745LysArg: 3.745 ± 0.081	4.078LysSer: 4.078 ± 0.084	4.333LysThr: 4.333 ± 0.083	5.303LysVal: 5.303 ± 0.114	0.727LysTrp: 0.727 ± 0.033	3.897LysTyr: 3.897 ± 0.087	0.0LysXaa: 0.0 ± 0.0
Leu	5.876LeuAla: 5.876 ± 0.11	1.138LeuCys: 1.138 ± 0.044	4.591LeuAsp: 4.591 ± 0.083	9.243LeuGlu: 9.243 ± 0.122	4.813LeuPhe: 4.813 ± 0.105	6.891LeuGly: 6.891 ± 0.121	1.743LeuHis: 1.743 ± 0.052	5.882LeuIle: 5.882 ± 0.113	7.924LeuLys: 7.924 ± 0.095	9.545LeuLeu: 9.545 ± 0.161	2.38LeuMet: 2.38 ± 0.066	4.11LeuAsn: 4.11 ± 0.085	3.115LeuPro: 3.115 ± 0.069	3.901LeuGln: 3.901 ± 0.083	3.833LeuArg: 3.833 ± 0.071	7.215LeuSer: 7.215 ± 0.121	4.351LeuThr: 4.351 ± 0.08	5.151LeuVal: 5.151 ± 0.08	0.848LeuTrp: 0.848 ± 0.036	3.411LeuTyr: 3.411 ± 0.074	0.001LeuXaa: 0.001 ± 0.001
Met	1.807MetAla: 1.807 ± 0.048	0.183MetCys: 0.183 ± 0.017	1.347MetAsp: 1.347 ± 0.047	2.756MetGlu: 2.756 ± 0.073	0.964MetPhe: 0.964 ± 0.042	1.856MetGly: 1.856 ± 0.061	0.322MetHis: 0.322 ± 0.021	2.507MetIle: 2.507 ± 0.077	3.344MetLys: 3.344 ± 0.081	2.562MetLeu: 2.562 ± 0.064	0.795MetMet: 0.795 ± 0.038	1.478MetAsn: 1.478 ± 0.054	0.812MetPro: 0.812 ± 0.038	0.861MetGln: 0.861 ± 0.039	1.084MetArg: 1.084 ± 0.039	1.513MetSer: 1.513 ± 0.045	1.49MetThr: 1.49 ± 0.044	1.531MetVal: 1.531 ± 0.051	0.168MetTrp: 0.168 ± 0.017	0.912MetTyr: 0.912 ± 0.037	0.0MetXaa: 0.0 ± 0.0
Asn	2.54AsnAla: 2.54 ± 0.07	0.474AsnCys: 0.474 ± 0.029	1.697AsnAsp: 1.697 ± 0.06	2.791AsnGlu: 2.791 ± 0.062	2.581AsnPhe: 2.581 ± 0.057	3.13AsnGly: 3.13 ± 0.074	0.922AsnHis: 0.922 ± 0.035	4.904AsnIle: 4.904 ± 0.094	3.713AsnLys: 3.713 ± 0.092	4.795AsnLeu: 4.795 ± 0.08	1.496AsnMet: 1.496 ± 0.047	2.065AsnAsn: 2.065 ± 0.059	2.149AsnPro: 2.149 ± 0.054	1.723AsnGln: 1.723 ± 0.052	2.163AsnArg: 2.163 ± 0.057	2.902AsnSer: 2.902 ± 0.085	2.501AsnThr: 2.501 ± 0.071	2.75AsnVal: 2.75 ± 0.068	0.423AsnTrp: 0.423 ± 0.022	2.248AsnTyr: 2.248 ± 0.059	0.0AsnXaa: 0.0 ± 0.0
Pro	1.528ProAla: 1.528 ± 0.059	0.313ProCys: 0.313 ± 0.021	1.223ProAsp: 1.223 ± 0.042	2.599ProGlu: 2.599 ± 0.067	1.607ProPhe: 1.607 ± 0.053	1.731ProGly: 1.731 ± 0.056	0.521ProHis: 0.521 ± 0.027	2.426ProIle: 2.426 ± 0.065	2.558ProLys: 2.558 ± 0.059	2.605ProLeu: 2.605 ± 0.071	0.836ProMet: 0.836 ± 0.035	1.488ProAsn: 1.488 ± 0.045	0.524ProPro: 0.524 ± 0.029	0.751ProGln: 0.751 ± 0.034	0.919ProArg: 0.919 ± 0.038	1.65ProSer: 1.65 ± 0.048	1.33ProThr: 1.33 ± 0.044	1.987ProVal: 1.987 ± 0.059	0.235ProTrp: 0.235 ± 0.018	1.284ProTyr: 1.284 ± 0.048	0.0ProXaa: 0.0 ± 0.0
Gln	2.002GlnAla: 2.002 ± 0.064	0.27GlnCys: 0.27 ± 0.021	1.618GlnAsp: 1.618 ± 0.057	3.879GlnGlu: 3.879 ± 0.084	1.335GlnPhe: 1.335 ± 0.04	2.286GlnGly: 2.286 ± 0.062	0.521GlnHis: 0.521 ± 0.028	2.531GlnIle: 2.531 ± 0.055	3.715GlnLys: 3.715 ± 0.087	2.766GlnLeu: 2.766 ± 0.069	0.784GlnMet: 0.784 ± 0.033	1.92GlnAsn: 1.92 ± 0.052	0.538GlnPro: 0.538 ± 0.029	1.111GlnGln: 1.111 ± 0.047	1.412GlnArg: 1.412 ± 0.045	1.676GlnSer: 1.676 ± 0.052	1.268GlnThr: 1.268 ± 0.044	1.869GlnVal: 1.869 ± 0.058	0.276GlnTrp: 0.276 ± 0.019	1.491GlnTyr: 1.491 ± 0.044	0.0GlnXaa: 0.0 ± 0.0
Arg	2.258ArgAla: 2.258 ± 0.06	0.338ArgCys: 0.338 ± 0.021	1.948ArgAsp: 1.948 ± 0.06	4.239ArgGlu: 4.239 ± 0.085	1.756ArgPhe: 1.756 ± 0.053	2.491ArgGly: 2.491 ± 0.068	0.572ArgHis: 0.572 ± 0.031	3.551ArgIle: 3.551 ± 0.079	4.466ArgLys: 4.466 ± 0.089	3.411ArgLeu: 3.411 ± 0.065	1.297ArgMet: 1.297 ± 0.047	2.343ArgAsn: 2.343 ± 0.059	0.859ArgPro: 0.859 ± 0.04	1.248ArgGln: 1.248 ± 0.045	1.983ArgArg: 1.983 ± 0.059	1.868ArgSer: 1.868 ± 0.056	1.571ArgThr: 1.571 ± 0.047	2.608ArgVal: 2.608 ± 0.062	0.301ArgTrp: 0.301 ± 0.02	1.74ArgTyr: 1.74 ± 0.06	0.0ArgXaa: 0.0 ± 0.0
Ser	3.22SerAla: 3.22 ± 0.093	0.657SerCys: 0.657 ± 0.039	2.432SerAsp: 2.432 ± 0.054	3.916SerGlu: 3.916 ± 0.079	3.874SerPhe: 3.874 ± 0.08	4.177SerGly: 4.177 ± 0.088	1.236SerHis: 1.236 ± 0.047	5.421SerIle: 5.421 ± 0.098	4.919SerLys: 4.919 ± 0.094	6.834SerLeu: 6.834 ± 0.124	1.871SerMet: 1.871 ± 0.057	2.605SerAsn: 2.605 ± 0.068	1.853SerPro: 1.853 ± 0.053	1.868SerGln: 1.868 ± 0.059	2.239SerArg: 2.239 ± 0.059	4.42SerSer: 4.42 ± 0.097	2.857SerThr: 2.857 ± 0.063	3.645SerVal: 3.645 ± 0.085	0.526SerTrp: 0.526 ± 0.031	2.984SerTyr: 2.984 ± 0.07	0.0SerXaa: 0.0 ± 0.0
Thr	2.991ThrAla: 2.991 ± 0.085	0.422ThrCys: 0.422 ± 0.026	2.172ThrAsp: 2.172 ± 0.06	3.675ThrGlu: 3.675 ± 0.072	2.172ThrPhe: 2.172 ± 0.052	3.734ThrGly: 3.734 ± 0.075	0.758ThrHis: 0.758 ± 0.034	3.731ThrIle: 3.731 ± 0.078	3.775ThrLys: 3.775 ± 0.072	4.647ThrLeu: 4.647 ± 0.095	1.141ThrMet: 1.141 ± 0.043	2.017ThrAsn: 2.017 ± 0.06	1.712ThrPro: 1.712 ± 0.049	1.229ThrGln: 1.229 ± 0.043	1.723ThrArg: 1.723 ± 0.048	2.842ThrSer: 2.842 ± 0.059	2.359ThrThr: 2.359 ± 0.065	3.287ThrVal: 3.287 ± 0.068	0.45ThrTrp: 0.45 ± 0.026	1.61ThrTyr: 1.61 ± 0.051	0.0ThrXaa: 0.0 ± 0.0
Val	4.061ValAla: 4.061 ± 0.104	0.666ValCys: 0.666 ± 0.032	3.031ValAsp: 3.031 ± 0.083	5.067ValGlu: 5.067 ± 0.1	2.979ValPhe: 2.979 ± 0.078	4.178ValGly: 4.178 ± 0.089	0.997ValHis: 0.997 ± 0.039	4.927ValIle: 4.927 ± 0.083	4.904ValLys: 4.904 ± 0.109	6.004ValLeu: 6.004 ± 0.101	1.554ValMet: 1.554 ± 0.055	2.838ValAsn: 2.838 ± 0.076	1.898ValPro: 1.898 ± 0.057	1.776ValGln: 1.776 ± 0.053	2.216ValArg: 2.216 ± 0.064	4.26ValSer: 4.26 ± 0.084	2.918ValThr: 2.918 ± 0.081	3.973ValVal: 3.973 ± 0.097	0.469ValTrp: 0.469 ± 0.026	2.263ValTyr: 2.263 ± 0.055	0.0ValXaa: 0.0 ± 0.0
Trp	0.381TrpAla: 0.381 ± 0.027	0.094TrpCys: 0.094 ± 0.012	0.371TrpAsp: 0.371 ± 0.024	0.778TrpGlu: 0.778 ± 0.036	0.328TrpPhe: 0.328 ± 0.021	0.535TrpGly: 0.535 ± 0.027	0.116TrpHis: 0.116 ± 0.014	0.815TrpIle: 0.815 ± 0.032	1.126TrpLys: 1.126 ± 0.046	0.663TrpLeu: 0.663 ± 0.028	0.282TrpMet: 0.282 ± 0.02	0.536TrpAsn: 0.536 ± 0.031	0.13TrpPro: 0.13 ± 0.011	0.285TrpGln: 0.285 ± 0.02	0.337TrpArg: 0.337 ± 0.025	0.401TrpSer: 0.401 ± 0.022	0.387TrpThr: 0.387 ± 0.026	0.369TrpVal: 0.369 ± 0.027	0.08TrpTrp: 0.08 ± 0.01	0.277TrpTyr: 0.277 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.261TyrAla: 2.261 ± 0.05	0.509TyrCys: 0.509 ± 0.024	2.158TyrAsp: 2.158 ± 0.06	3.134TyrGlu: 3.134 ± 0.079	2.452TyrPhe: 2.452 ± 0.055	2.687TyrGly: 2.687 ± 0.065	0.973TyrHis: 0.973 ± 0.039	2.994TyrIle: 2.994 ± 0.081	2.754TyrLys: 2.754 ± 0.074	4.211TyrLeu: 4.211 ± 0.078	0.971TyrMet: 0.971 ± 0.036	1.768TyrAsn: 1.768 ± 0.058	1.47TyrPro: 1.47 ± 0.048	2.036TyrGln: 2.036 ± 0.064	2.047TyrArg: 2.047 ± 0.058	2.909TyrSer: 2.909 ± 0.078	1.816TyrThr: 1.816 ± 0.049	2.158TyrVal: 2.158 ± 0.052	0.422TyrTrp: 0.422 ± 0.024	1.959TyrTyr: 1.959 ± 0.06	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.001XaaGly: 0.001 ± 0.001	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3196 proteins (671340 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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