Amino acid dipepetide frequency for Blochmannia endosymbiont of Polyrhachis (Hedomyrma) turneri

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.275AlaAla: 3.275 ± 0.14
0.833AlaCys: 0.833 ± 0.071
1.888AlaAsp: 1.888 ± 0.095
2.256AlaGlu: 2.256 ± 0.125
1.842AlaPhe: 1.842 ± 0.107
3.24AlaGly: 3.24 ± 0.158
1.11AlaHis: 1.11 ± 0.079
5.224AlaIle: 5.224 ± 0.168
3.18AlaLys: 3.18 ± 0.127
5.36AlaLeu: 5.36 ± 0.166
1.368AlaMet: 1.368 ± 0.091
2.64AlaAsn: 2.64 ± 0.119
1.317AlaPro: 1.317 ± 0.081
1.812AlaGln: 1.812 ± 0.087
2.503AlaArg: 2.503 ± 0.123
3.124AlaSer: 3.124 ± 0.151
2.534AlaThr: 2.534 ± 0.124
3.195AlaVal: 3.195 ± 0.138
0.53AlaTrp: 0.53 ± 0.05
1.877AlaTyr: 1.877 ± 0.101
0.0AlaXaa: 0.0 ± 0.0
Cys
0.833CysAla: 0.833 ± 0.064
0.363CysCys: 0.363 ± 0.037
0.974CysAsp: 0.974 ± 0.083
0.681CysGlu: 0.681 ± 0.061
0.883CysPhe: 0.883 ± 0.066
1.156CysGly: 1.156 ± 0.074
0.434CysHis: 0.434 ± 0.052
1.554CysIle: 1.554 ± 0.088
0.868CysLys: 0.868 ± 0.068
1.625CysLeu: 1.625 ± 0.079
0.399CysMet: 0.399 ± 0.042
1.125CysAsn: 1.125 ± 0.073
0.525CysPro: 0.525 ± 0.056
0.59CysGln: 0.59 ± 0.049
0.656CysArg: 0.656 ± 0.062
1.358CysSer: 1.358 ± 0.082
0.671CysThr: 0.671 ± 0.054
1.257CysVal: 1.257 ± 0.096
0.242CysTrp: 0.242 ± 0.036
0.757CysTyr: 0.757 ± 0.069
0.0CysXaa: 0.0 ± 0.0
Asp
2.11AspAla: 2.11 ± 0.094
0.762AspCys: 0.762 ± 0.066
1.953AspAsp: 1.953 ± 0.113
2.19AspGlu: 2.19 ± 0.111
2.508AspPhe: 2.508 ± 0.102
2.407AspGly: 2.407 ± 0.14
1.156AspHis: 1.156 ± 0.079
5.587AspIle: 5.587 ± 0.184
2.776AspLys: 2.776 ± 0.116
4.35AspLeu: 4.35 ± 0.133
1.247AspMet: 1.247 ± 0.076
2.781AspAsn: 2.781 ± 0.121
1.479AspPro: 1.479 ± 0.095
1.479AspGln: 1.479 ± 0.09
2.125AspArg: 2.125 ± 0.129
2.756AspSer: 2.756 ± 0.123
2.291AspThr: 2.291 ± 0.111
3.548AspVal: 3.548 ± 0.175
0.515AspTrp: 0.515 ± 0.058
1.802AspTyr: 1.802 ± 0.099
0.0AspXaa: 0.0 ± 0.0
Glu
2.251GluAla: 2.251 ± 0.126
0.717GluCys: 0.717 ± 0.059
1.812GluAsp: 1.812 ± 0.113
2.574GluGlu: 2.574 ± 0.153
2.024GluPhe: 2.024 ± 0.108
2.135GluGly: 2.135 ± 0.126
1.282GluHis: 1.282 ± 0.076
5.365GluIle: 5.365 ± 0.185
3.841GluLys: 3.841 ± 0.133
5.027GluLeu: 5.027 ± 0.146
1.191GluMet: 1.191 ± 0.078
2.942GluAsn: 2.942 ± 0.133
1.206GluPro: 1.206 ± 0.084
1.711GluGln: 1.711 ± 0.098
2.352GluArg: 2.352 ± 0.109
3.195GluSer: 3.195 ± 0.161
2.009GluThr: 2.009 ± 0.11
2.892GluVal: 2.892 ± 0.142
0.414GluTrp: 0.414 ± 0.045
1.877GluTyr: 1.877 ± 0.096
0.0GluXaa: 0.0 ± 0.0
Phe
1.696PheAla: 1.696 ± 0.103
1.045PheCys: 1.045 ± 0.08
2.392PheAsp: 2.392 ± 0.119
1.913PheGlu: 1.913 ± 0.112
2.993PhePhe: 2.993 ± 0.139
3.477PheGly: 3.477 ± 0.164
1.206PheHis: 1.206 ± 0.078
4.547PheIle: 4.547 ± 0.183
2.443PheLys: 2.443 ± 0.104
4.885PheLeu: 4.885 ± 0.189
1.136PheMet: 1.136 ± 0.072
2.887PheAsn: 2.887 ± 0.124
1.807PhePro: 1.807 ± 0.121
1.433PheGln: 1.433 ± 0.085
1.882PheArg: 1.882 ± 0.114
4.542PheSer: 4.542 ± 0.143
1.933PheThr: 1.933 ± 0.101
2.609PheVal: 2.609 ± 0.144
0.5PheTrp: 0.5 ± 0.051
1.948PheTyr: 1.948 ± 0.114
0.0PheXaa: 0.0 ± 0.0
Gly
3.452GlyAla: 3.452 ± 0.182
1.08GlyCys: 1.08 ± 0.066
2.897GlyAsp: 2.897 ± 0.146
2.927GlyGlu: 2.927 ± 0.132
2.584GlyPhe: 2.584 ± 0.113
4.133GlyGly: 4.133 ± 0.18
1.615GlyHis: 1.615 ± 0.098
6.733GlyIle: 6.733 ± 0.202
3.967GlyLys: 3.967 ± 0.176
5.229GlyLeu: 5.229 ± 0.172
1.696GlyMet: 1.696 ± 0.093
2.922GlyAsn: 2.922 ± 0.142
1.454GlyPro: 1.454 ± 0.088
1.771GlyGln: 1.771 ± 0.107
2.816GlyArg: 2.816 ± 0.161
3.578GlySer: 3.578 ± 0.162
3.048GlyThr: 3.048 ± 0.156
4.557GlyVal: 4.557 ± 0.17
0.565GlyTrp: 0.565 ± 0.062
2.539GlyTyr: 2.539 ± 0.112
0.0GlyXaa: 0.0 ± 0.0
His
1.6HisAla: 1.6 ± 0.094
0.389HisCys: 0.389 ± 0.045
1.181HisAsp: 1.181 ± 0.067
1.221HisGlu: 1.221 ± 0.085
1.07HisPhe: 1.07 ± 0.08
1.832HisGly: 1.832 ± 0.098
0.802HisHis: 0.802 ± 0.065
2.735HisIle: 2.735 ± 0.139
1.499HisLys: 1.499 ± 0.104
2.105HisLeu: 2.105 ± 0.086
0.585HisMet: 0.585 ± 0.05
1.756HisAsn: 1.756 ± 0.104
1.332HisPro: 1.332 ± 0.088
1.025HisGln: 1.025 ± 0.078
1.216HisArg: 1.216 ± 0.073
1.66HisSer: 1.66 ± 0.09
1.554HisThr: 1.554 ± 0.105
1.645HisVal: 1.645 ± 0.097
0.313HisTrp: 0.313 ± 0.045
0.969HisTyr: 0.969 ± 0.07
0.0HisXaa: 0.0 ± 0.0
Ile
5.663IleAla: 5.663 ± 0.187
1.62IleCys: 1.62 ± 0.091
5.405IleAsp: 5.405 ± 0.183
4.901IleGlu: 4.901 ± 0.162
5.249IlePhe: 5.249 ± 0.205
6.45IleGly: 6.45 ± 0.228
2.776IleHis: 2.776 ± 0.134
10.891IleIle: 10.891 ± 0.367
6.606IleLys: 6.606 ± 0.208
10.336IleLeu: 10.336 ± 0.29
2.387IleMet: 2.387 ± 0.092
7.348IleAsn: 7.348 ± 0.247
3.679IlePro: 3.679 ± 0.157
3.76IleGln: 3.76 ± 0.174
4.522IleArg: 4.522 ± 0.167
8.146IleSer: 8.146 ± 0.206
5.794IleThr: 5.794 ± 0.233
5.723IleVal: 5.723 ± 0.203
0.959IleTrp: 0.959 ± 0.076
3.674IleTyr: 3.674 ± 0.147
0.0IleXaa: 0.0 ± 0.0
Lys
2.009LysAla: 2.009 ± 0.108
0.868LysCys: 0.868 ± 0.067
2.609LysAsp: 2.609 ± 0.129
2.968LysGlu: 2.968 ± 0.133
2.862LysPhe: 2.862 ± 0.14
2.534LysGly: 2.534 ± 0.131
1.963LysHis: 1.963 ± 0.111
8.353LysIle: 8.353 ± 0.274
7.54LysLys: 7.54 ± 0.269
6.379LysLeu: 6.379 ± 0.163
1.701LysMet: 1.701 ± 0.088
6.445LysAsn: 6.445 ± 0.228
1.494LysPro: 1.494 ± 0.083
2.594LysGln: 2.594 ± 0.124
2.867LysArg: 2.867 ± 0.126
4.078LysSer: 4.078 ± 0.133
3.412LysThr: 3.412 ± 0.159
3.124LysVal: 3.124 ± 0.137
0.454LysTrp: 0.454 ± 0.047
3.28LysTyr: 3.28 ± 0.143
0.0LysXaa: 0.0 ± 0.0
Leu
5.097LeuAla: 5.097 ± 0.153
1.756LeuCys: 1.756 ± 0.079
4.583LeuAsp: 4.583 ± 0.153
5.254LeuGlu: 5.254 ± 0.159
4.82LeuPhe: 4.82 ± 0.186
5.607LeuGly: 5.607 ± 0.186
2.846LeuHis: 2.846 ± 0.145
9.034LeuIle: 9.034 ± 0.283
6.859LeuLys: 6.859 ± 0.191
11.456LeuLeu: 11.456 ± 0.345
2.357LeuMet: 2.357 ± 0.098
6.157LeuAsn: 6.157 ± 0.198
4.007LeuPro: 4.007 ± 0.155
3.795LeuGln: 3.795 ± 0.146
4.527LeuArg: 4.527 ± 0.148
8.469LeuSer: 8.469 ± 0.246
4.81LeuThr: 4.81 ± 0.157
5.516LeuVal: 5.516 ± 0.218
0.908LeuTrp: 0.908 ± 0.068
3.669LeuTyr: 3.669 ± 0.149
0.0LeuXaa: 0.0 ± 0.0
Met
1.221MetAla: 1.221 ± 0.074
0.379MetCys: 0.379 ± 0.04
0.949MetAsp: 0.949 ± 0.058
1.075MetGlu: 1.075 ± 0.076
1.08MetPhe: 1.08 ± 0.074
1.504MetGly: 1.504 ± 0.101
0.626MetHis: 0.626 ± 0.056
2.296MetIle: 2.296 ± 0.107
1.802MetLys: 1.802 ± 0.102
2.947MetLeu: 2.947 ± 0.113
0.732MetMet: 0.732 ± 0.055
1.706MetAsn: 1.706 ± 0.096
0.833MetPro: 0.833 ± 0.068
0.949MetGln: 0.949 ± 0.067
1.201MetArg: 1.201 ± 0.085
1.787MetSer: 1.787 ± 0.098
1.009MetThr: 1.009 ± 0.066
1.524MetVal: 1.524 ± 0.106
0.197MetTrp: 0.197 ± 0.035
0.833MetTyr: 0.833 ± 0.066
0.0MetXaa: 0.0 ± 0.0
Asn
2.382AsnAla: 2.382 ± 0.121
0.939AsnCys: 0.939 ± 0.062
3.084AsnAsp: 3.084 ± 0.129
2.614AsnGlu: 2.614 ± 0.107
3.255AsnPhe: 3.255 ± 0.147
2.836AsnGly: 2.836 ± 0.128
1.605AsnHis: 1.605 ± 0.098
9.024AsnIle: 9.024 ± 0.31
5.087AsnLys: 5.087 ± 0.213
5.203AsnLeu: 5.203 ± 0.155
1.65AsnMet: 1.65 ± 0.087
5.764AsnAsn: 5.764 ± 0.276
1.882AsnPro: 1.882 ± 0.088
2.579AsnGln: 2.579 ± 0.134
2.493AsnArg: 2.493 ± 0.107
3.679AsnSer: 3.679 ± 0.155
3.795AsnThr: 3.795 ± 0.194
3.74AsnVal: 3.74 ± 0.151
0.702AsnTrp: 0.702 ± 0.06
2.493AsnTyr: 2.493 ± 0.131
0.0AsnXaa: 0.0 ± 0.0
Pro
1.363ProAla: 1.363 ± 0.09
0.53ProCys: 0.53 ± 0.045
1.403ProAsp: 1.403 ± 0.082
1.792ProGlu: 1.792 ± 0.094
1.448ProPhe: 1.448 ± 0.078
2.211ProGly: 2.211 ± 0.124
0.848ProHis: 0.848 ± 0.069
3.578ProIle: 3.578 ± 0.142
1.958ProLys: 1.958 ± 0.097
3.069ProLeu: 3.069 ± 0.127
0.792ProMet: 0.792 ± 0.064
2.054ProAsn: 2.054 ± 0.114
0.913ProPro: 0.913 ± 0.068
1.014ProGln: 1.014 ± 0.079
1.156ProArg: 1.156 ± 0.078
2.135ProSer: 2.135 ± 0.106
1.696ProThr: 1.696 ± 0.104
2.327ProVal: 2.327 ± 0.121
0.368ProTrp: 0.368 ± 0.047
1.368ProTyr: 1.368 ± 0.085
0.0ProXaa: 0.0 ± 0.0
Gln
1.983GlnAla: 1.983 ± 0.108
0.58GlnCys: 0.58 ± 0.052
1.277GlnAsp: 1.277 ± 0.072
2.135GlnGlu: 2.135 ± 0.122
1.665GlnPhe: 1.665 ± 0.083
2.054GlnGly: 2.054 ± 0.096
1.004GlnHis: 1.004 ± 0.071
3.503GlnIle: 3.503 ± 0.153
2.705GlnLys: 2.705 ± 0.135
3.937GlnLeu: 3.937 ± 0.145
0.686GlnMet: 0.686 ± 0.054
2.13GlnAsn: 2.13 ± 0.129
1.136GlnPro: 1.136 ± 0.081
1.696GlnGln: 1.696 ± 0.107
1.62GlnArg: 1.62 ± 0.092
2.407GlnSer: 2.407 ± 0.117
1.817GlnThr: 1.817 ± 0.116
1.913GlnVal: 1.913 ± 0.1
0.419GlnTrp: 0.419 ± 0.045
1.923GlnTyr: 1.923 ± 0.117
0.0GlnXaa: 0.0 ± 0.0
Arg
2.493ArgAla: 2.493 ± 0.112
0.818ArgCys: 0.818 ± 0.071
2.039ArgAsp: 2.039 ± 0.113
2.165ArgGlu: 2.165 ± 0.112
2.281ArgPhe: 2.281 ± 0.111
2.498ArgGly: 2.498 ± 0.125
1.115ArgHis: 1.115 ± 0.081
4.002ArgIle: 4.002 ± 0.151
2.65ArgLys: 2.65 ± 0.123
4.547ArgLeu: 4.547 ± 0.163
1.161ArgMet: 1.161 ± 0.078
2.614ArgAsn: 2.614 ± 0.104
1.307ArgPro: 1.307 ± 0.075
1.751ArgGln: 1.751 ± 0.094
2.115ArgArg: 2.115 ± 0.116
3.195ArgSer: 3.195 ± 0.138
1.857ArgThr: 1.857 ± 0.094
3.089ArgVal: 3.089 ± 0.177
0.575ArgTrp: 0.575 ± 0.061
2.094ArgTyr: 2.094 ± 0.104
0.0ArgXaa: 0.0 ± 0.0
Ser
3.573SerAla: 3.573 ± 0.15
1.332SerCys: 1.332 ± 0.09
3.422SerAsp: 3.422 ± 0.144
3.321SerGlu: 3.321 ± 0.139
3.265SerPhe: 3.265 ± 0.144
5.274SerGly: 5.274 ± 0.159
1.701SerHis: 1.701 ± 0.099
6.95SerIle: 6.95 ± 0.211
4.159SerLys: 4.159 ± 0.151
7.01SerLeu: 7.01 ± 0.219
1.898SerMet: 1.898 ± 0.089
4.088SerAsn: 4.088 ± 0.157
1.893SerPro: 1.893 ± 0.091
2.433SerGln: 2.433 ± 0.118
2.937SerArg: 2.937 ± 0.145
5.133SerSer: 5.133 ± 0.196
3.371SerThr: 3.371 ± 0.14
4.845SerVal: 4.845 ± 0.18
0.626SerTrp: 0.626 ± 0.055
2.65SerTyr: 2.65 ± 0.12
0.0SerXaa: 0.0 ± 0.0
Thr
2.483ThrAla: 2.483 ± 0.123
0.742ThrCys: 0.742 ± 0.066
2.19ThrAsp: 2.19 ± 0.095
2.11ThrGlu: 2.11 ± 0.122
2.039ThrPhe: 2.039 ± 0.102
3.376ThrGly: 3.376 ± 0.136
1.474ThrHis: 1.474 ± 0.091
5.446ThrIle: 5.446 ± 0.23
2.988ThrLys: 2.988 ± 0.14
5.925ThrLeu: 5.925 ± 0.193
0.873ThrMet: 0.873 ± 0.065
2.912ThrAsn: 2.912 ± 0.151
1.999ThrPro: 1.999 ± 0.121
1.908ThrGln: 1.908 ± 0.109
1.953ThrArg: 1.953 ± 0.088
3.084ThrSer: 3.084 ± 0.116
2.645ThrThr: 2.645 ± 0.141
2.831ThrVal: 2.831 ± 0.122
0.611ThrTrp: 0.611 ± 0.064
1.716ThrTyr: 1.716 ± 0.101
0.0ThrXaa: 0.0 ± 0.0
Val
3.301ValAla: 3.301 ± 0.134
1.131ValCys: 1.131 ± 0.083
3.316ValAsp: 3.316 ± 0.154
2.614ValGlu: 2.614 ± 0.141
2.912ValPhe: 2.912 ± 0.152
3.891ValGly: 3.891 ± 0.159
1.428ValHis: 1.428 ± 0.085
6.314ValIle: 6.314 ± 0.192
3.513ValLys: 3.513 ± 0.146
6.662ValLeu: 6.662 ± 0.25
1.681ValMet: 1.681 ± 0.116
3.255ValAsn: 3.255 ± 0.14
2.11ValPro: 2.11 ± 0.105
1.958ValGln: 1.958 ± 0.1
3.099ValArg: 3.099 ± 0.14
4.396ValSer: 4.396 ± 0.161
2.902ValThr: 2.902 ± 0.122
4.83ValVal: 4.83 ± 0.258
0.51ValTrp: 0.51 ± 0.058
2.004ValTyr: 2.004 ± 0.108
0.0ValXaa: 0.0 ± 0.0
Trp
0.368TrpAla: 0.368 ± 0.039
0.192TrpCys: 0.192 ± 0.039
0.419TrpAsp: 0.419 ± 0.053
0.5TrpGlu: 0.5 ± 0.045
0.459TrpPhe: 0.459 ± 0.051
0.469TrpGly: 0.469 ± 0.051
0.288TrpHis: 0.288 ± 0.035
1.1TrpIle: 1.1 ± 0.082
0.873TrpLys: 0.873 ± 0.071
1.337TrpLeu: 1.337 ± 0.088
0.288TrpMet: 0.288 ± 0.035
0.575TrpAsn: 0.575 ± 0.059
0.303TrpPro: 0.303 ± 0.037
0.404TrpGln: 0.404 ± 0.046
0.505TrpArg: 0.505 ± 0.055
0.525TrpSer: 0.525 ± 0.052
0.358TrpThr: 0.358 ± 0.04
0.51TrpVal: 0.51 ± 0.054
0.091TrpTrp: 0.091 ± 0.02
0.429TrpTyr: 0.429 ± 0.043
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.953TyrAla: 1.953 ± 0.103
0.878TyrCys: 0.878 ± 0.067
2.029TyrAsp: 2.029 ± 0.084
1.605TyrGlu: 1.605 ± 0.094
2.034TyrPhe: 2.034 ± 0.11
2.478TyrGly: 2.478 ± 0.129
1.211TyrHis: 1.211 ± 0.087
3.654TyrIle: 3.654 ± 0.13
2.221TyrLys: 2.221 ± 0.119
4.143TyrLeu: 4.143 ± 0.16
0.818TyrMet: 0.818 ± 0.067
2.705TyrAsn: 2.705 ± 0.126
1.348TyrPro: 1.348 ± 0.092
1.928TyrGln: 1.928 ± 0.108
1.822TyrArg: 1.822 ± 0.102
2.634TyrSer: 2.634 ± 0.129
1.797TyrThr: 1.797 ± 0.101
2.15TyrVal: 2.15 ± 0.099
0.495TyrTrp: 0.495 ± 0.053
1.691TyrTyr: 1.691 ± 0.104
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 589 proteins (198143 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski