Amino acid dipepetide frequency for Feline papillomavirus type 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.91AlaAla: 5.91 ± 2.232
0.844AlaCys: 0.844 ± 0.691
3.799AlaAsp: 3.799 ± 1.432
5.488AlaGlu: 5.488 ± 1.731
1.266AlaPhe: 1.266 ± 0.439
3.799AlaGly: 3.799 ± 1.663
1.266AlaHis: 1.266 ± 0.417
1.688AlaIle: 1.688 ± 0.626
1.688AlaLys: 1.688 ± 0.626
6.332AlaLeu: 6.332 ± 2.471
1.688AlaMet: 1.688 ± 0.883
2.533AlaAsn: 2.533 ± 1.009
6.754AlaPro: 6.754 ± 2.213
2.955AlaGln: 2.955 ± 0.934
6.332AlaArg: 6.332 ± 1.543
4.221AlaSer: 4.221 ± 0.982
4.221AlaThr: 4.221 ± 1.053
4.221AlaVal: 4.221 ± 1.925
1.688AlaTrp: 1.688 ± 0.846
2.533AlaTyr: 2.533 ± 0.515
0.0AlaXaa: 0.0 ± 0.0
Cys
0.844CysAla: 0.844 ± 0.423
0.422CysCys: 0.422 ± 0.379
1.266CysAsp: 1.266 ± 0.693
1.688CysGlu: 1.688 ± 1.053
0.0CysPhe: 0.0 ± 0.0
2.955CysGly: 2.955 ± 1.468
0.422CysHis: 0.422 ± 0.382
1.266CysIle: 1.266 ± 0.93
1.688CysLys: 1.688 ± 0.648
3.377CysLeu: 3.377 ± 1.631
0.0CysMet: 0.0 ± 0.0
0.844CysAsn: 0.844 ± 0.669
2.533CysPro: 2.533 ± 0.565
1.266CysGln: 1.266 ± 0.712
0.844CysArg: 0.844 ± 1.068
1.688CysSer: 1.688 ± 1.338
0.844CysThr: 0.844 ± 0.551
2.533CysVal: 2.533 ± 1.132
0.844CysTrp: 0.844 ± 0.423
0.844CysTyr: 0.844 ± 0.551
0.0CysXaa: 0.0 ± 0.0
Asp
4.643AspAla: 4.643 ± 1.328
1.266AspCys: 1.266 ± 1.147
2.955AspAsp: 2.955 ± 1.331
2.533AspGlu: 2.533 ± 0.423
1.688AspPhe: 1.688 ± 0.554
6.754AspGly: 6.754 ± 1.376
0.844AspHis: 0.844 ± 0.627
3.799AspIle: 3.799 ± 1.154
2.533AspLys: 2.533 ± 0.516
6.754AspLeu: 6.754 ± 2.499
1.266AspMet: 1.266 ± 0.731
2.533AspAsn: 2.533 ± 0.891
4.643AspPro: 4.643 ± 1.755
1.266AspGln: 1.266 ± 0.666
2.533AspArg: 2.533 ± 1.201
4.643AspSer: 4.643 ± 1.289
2.955AspThr: 2.955 ± 0.524
5.488AspVal: 5.488 ± 2.218
1.688AspTrp: 1.688 ± 0.846
2.955AspTyr: 2.955 ± 0.692
0.0AspXaa: 0.0 ± 0.0
Glu
5.065GluAla: 5.065 ± 1.142
1.266GluCys: 1.266 ± 1.147
5.065GluAsp: 5.065 ± 0.818
4.643GluGlu: 4.643 ± 1.171
0.0GluPhe: 0.0 ± 0.0
2.533GluGly: 2.533 ± 1.497
1.266GluHis: 1.266 ± 0.574
1.688GluIle: 1.688 ± 0.887
1.266GluLys: 1.266 ± 0.689
5.065GluLeu: 5.065 ± 0.776
0.844GluMet: 0.844 ± 0.423
2.533GluAsn: 2.533 ± 1.383
2.111GluPro: 2.111 ± 0.737
0.844GluGln: 0.844 ± 0.423
2.533GluArg: 2.533 ± 1.098
2.533GluSer: 2.533 ± 0.784
4.221GluThr: 4.221 ± 1.172
3.799GluVal: 3.799 ± 1.209
1.688GluTrp: 1.688 ± 0.514
2.111GluTyr: 2.111 ± 0.713
0.0GluXaa: 0.0 ± 0.0
Phe
2.955PheAla: 2.955 ± 1.703
0.844PheCys: 0.844 ± 1.068
2.533PheAsp: 2.533 ± 0.556
0.844PheGlu: 0.844 ± 0.442
1.688PhePhe: 1.688 ± 0.62
2.533PheGly: 2.533 ± 0.834
0.0PheHis: 0.0 ± 0.0
0.844PheIle: 0.844 ± 0.627
2.111PheLys: 2.111 ± 1.131
2.955PheLeu: 2.955 ± 1.021
0.844PheMet: 0.844 ± 0.437
1.266PheAsn: 1.266 ± 1.021
1.266PhePro: 1.266 ± 0.384
2.533PheGln: 2.533 ± 0.739
2.955PheArg: 2.955 ± 0.507
1.688PheSer: 1.688 ± 0.188
2.533PheThr: 2.533 ± 1.434
0.844PheVal: 0.844 ± 0.423
1.266PheTrp: 1.266 ± 0.666
0.844PheTyr: 0.844 ± 0.442
0.0PheXaa: 0.0 ± 0.0
Gly
8.02GlyAla: 8.02 ± 2.357
1.266GlyCys: 1.266 ± 0.384
7.176GlyAsp: 7.176 ± 1.406
3.799GlyGlu: 3.799 ± 1.419
2.955GlyPhe: 2.955 ± 1.232
10.131GlyGly: 10.131 ± 4.51
2.111GlyHis: 2.111 ± 0.786
3.799GlyIle: 3.799 ± 1.076
3.799GlyLys: 3.799 ± 1.837
4.221GlyLeu: 4.221 ± 2.22
0.844GlyMet: 0.844 ± 0.442
2.955GlyAsn: 2.955 ± 0.724
8.864GlyPro: 8.864 ± 2.978
3.799GlyGln: 3.799 ± 1.415
6.332GlyArg: 6.332 ± 1.552
7.176GlySer: 7.176 ± 0.796
8.864GlyThr: 8.864 ± 2.442
5.91GlyVal: 5.91 ± 1.282
0.422GlyTrp: 0.422 ± 0.379
1.266GlyTyr: 1.266 ± 0.347
0.0GlyXaa: 0.0 ± 0.0
His
1.266HisAla: 1.266 ± 0.692
0.844HisCys: 0.844 ± 0.669
0.0HisAsp: 0.0 ± 0.0
1.266HisGlu: 1.266 ± 0.574
2.111HisPhe: 2.111 ± 1.135
1.266HisGly: 1.266 ± 0.724
0.422HisHis: 0.422 ± 0.398
0.0HisIle: 0.0 ± 0.0
0.844HisLys: 0.844 ± 0.765
2.111HisLeu: 2.111 ± 0.963
0.422HisMet: 0.422 ± 0.379
0.422HisAsn: 0.422 ± 0.382
2.111HisPro: 2.111 ± 0.426
0.422HisGln: 0.422 ± 0.382
1.266HisArg: 1.266 ± 0.58
0.0HisSer: 0.0 ± 0.0
2.111HisThr: 2.111 ± 1.001
1.266HisVal: 1.266 ± 0.417
1.688HisTrp: 1.688 ± 0.635
0.844HisTyr: 0.844 ± 0.759
0.0HisXaa: 0.0 ± 0.0
Ile
2.533IleAla: 2.533 ± 0.773
1.266IleCys: 1.266 ± 0.666
1.266IleAsp: 1.266 ± 0.417
3.799IleGlu: 3.799 ± 1.23
0.844IlePhe: 0.844 ± 0.423
3.799IleGly: 3.799 ± 1.506
0.844IleHis: 0.844 ± 0.551
0.844IleIle: 0.844 ± 0.441
2.111IleLys: 2.111 ± 0.785
2.533IleLeu: 2.533 ± 1.06
1.266IleMet: 1.266 ± 0.632
0.422IleAsn: 0.422 ± 0.382
2.955IlePro: 2.955 ± 1.86
0.844IleGln: 0.844 ± 0.765
1.688IleArg: 1.688 ± 1.313
3.377IleSer: 3.377 ± 0.634
0.844IleThr: 0.844 ± 0.441
1.688IleVal: 1.688 ± 0.634
0.422IleTrp: 0.422 ± 0.534
0.422IleTyr: 0.422 ± 0.34
0.0IleXaa: 0.0 ± 0.0
Lys
2.533LysAla: 2.533 ± 0.748
1.266LysCys: 1.266 ± 0.712
4.221LysAsp: 4.221 ± 1.05
1.266LysGlu: 1.266 ± 0.666
2.955LysPhe: 2.955 ± 1.544
2.111LysGly: 2.111 ± 0.914
1.266LysHis: 1.266 ± 0.712
0.844LysIle: 0.844 ± 0.441
1.688LysLys: 1.688 ± 0.635
2.111LysLeu: 2.111 ± 0.806
0.844LysMet: 0.844 ± 0.989
0.422LysAsn: 0.422 ± 0.382
0.0LysPro: 0.0 ± 0.0
2.955LysGln: 2.955 ± 0.978
4.221LysArg: 4.221 ± 0.928
1.688LysSer: 1.688 ± 1.529
2.111LysThr: 2.111 ± 0.921
2.533LysVal: 2.533 ± 1.332
0.0LysTrp: 0.0 ± 0.0
1.266LysTyr: 1.266 ± 0.717
0.0LysXaa: 0.0 ± 0.0
Leu
5.488LeuAla: 5.488 ± 0.903
2.955LeuCys: 2.955 ± 1.583
7.598LeuAsp: 7.598 ± 1.038
3.377LeuGlu: 3.377 ± 1.439
4.221LeuPhe: 4.221 ± 1.338
8.02LeuGly: 8.02 ± 2.959
2.533LeuHis: 2.533 ± 0.672
1.688LeuIle: 1.688 ± 0.846
3.799LeuLys: 3.799 ± 0.932
10.553LeuLeu: 10.553 ± 1.703
1.688LeuMet: 1.688 ± 0.71
2.533LeuAsn: 2.533 ± 1.349
3.799LeuPro: 3.799 ± 1.289
5.488LeuGln: 5.488 ± 2.059
4.643LeuArg: 4.643 ± 0.913
5.91LeuSer: 5.91 ± 1.881
5.488LeuThr: 5.488 ± 1.535
5.91LeuVal: 5.91 ± 1.512
0.844LeuTrp: 0.844 ± 0.765
3.799LeuTyr: 3.799 ± 0.657
0.0LeuXaa: 0.0 ± 0.0
Met
1.266MetAla: 1.266 ± 0.731
0.0MetCys: 0.0 ± 0.0
0.844MetAsp: 0.844 ± 0.423
0.844MetGlu: 0.844 ± 0.657
0.422MetPhe: 0.422 ± 0.382
2.111MetGly: 2.111 ± 0.826
0.422MetHis: 0.422 ± 0.382
1.266MetIle: 1.266 ± 0.657
0.0MetLys: 0.0 ± 0.0
0.422MetLeu: 0.422 ± 0.379
0.844MetMet: 0.844 ± 0.423
0.422MetAsn: 0.422 ± 0.34
0.422MetPro: 0.422 ± 0.382
0.844MetGln: 0.844 ± 0.423
1.266MetArg: 1.266 ± 0.721
2.533MetSer: 2.533 ± 0.423
0.0MetThr: 0.0 ± 0.0
1.266MetVal: 1.266 ± 0.724
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.377AsnAla: 3.377 ± 1.586
0.844AsnCys: 0.844 ± 0.423
0.844AsnAsp: 0.844 ± 0.765
1.266AsnGlu: 1.266 ± 0.678
0.844AsnPhe: 0.844 ± 0.423
1.266AsnGly: 1.266 ± 0.574
0.0AsnHis: 0.0 ± 0.0
0.844AsnIle: 0.844 ± 0.441
0.844AsnLys: 0.844 ± 0.441
2.955AsnLeu: 2.955 ± 0.605
0.844AsnMet: 0.844 ± 0.423
1.266AsnAsn: 1.266 ± 0.666
2.111AsnPro: 2.111 ± 0.91
2.111AsnGln: 2.111 ± 0.713
2.111AsnArg: 2.111 ± 1.702
2.533AsnSer: 2.533 ± 0.725
2.111AsnThr: 2.111 ± 0.732
1.266AsnVal: 1.266 ± 0.384
0.422AsnTrp: 0.422 ± 0.382
0.422AsnTyr: 0.422 ± 0.34
0.0AsnXaa: 0.0 ± 0.0
Pro
7.176ProAla: 7.176 ± 2.065
3.377ProCys: 3.377 ± 1.915
3.377ProAsp: 3.377 ± 1.483
5.488ProGlu: 5.488 ± 1.253
1.266ProPhe: 1.266 ± 0.721
6.332ProGly: 6.332 ± 2.903
1.266ProHis: 1.266 ± 0.712
2.111ProIle: 2.111 ± 0.426
2.955ProLys: 2.955 ± 0.934
8.442ProLeu: 8.442 ± 2.173
0.0ProMet: 0.0 ± 0.0
2.111ProAsn: 2.111 ± 0.412
11.397ProPro: 11.397 ± 3.674
2.955ProGln: 2.955 ± 1.452
2.111ProArg: 2.111 ± 0.645
6.754ProSer: 6.754 ± 1.904
2.955ProThr: 2.955 ± 1.025
2.955ProVal: 2.955 ± 0.731
0.422ProTrp: 0.422 ± 0.398
2.533ProTyr: 2.533 ± 1.178
0.0ProXaa: 0.0 ± 0.0
Gln
2.955GlnAla: 2.955 ± 1.229
0.844GlnCys: 0.844 ± 0.765
2.533GlnAsp: 2.533 ± 0.953
2.955GlnGlu: 2.955 ± 0.455
2.111GlnPhe: 2.111 ± 0.802
2.955GlnGly: 2.955 ± 0.965
2.111GlnHis: 2.111 ± 1.102
2.955GlnIle: 2.955 ± 1.517
0.422GlnLys: 0.422 ± 0.34
4.221GlnLeu: 4.221 ± 1.844
0.422GlnMet: 0.422 ± 0.466
0.844GlnAsn: 0.844 ± 0.423
3.377GlnPro: 3.377 ± 0.766
2.533GlnGln: 2.533 ± 0.956
2.111GlnArg: 2.111 ± 0.412
1.688GlnSer: 1.688 ± 0.846
2.111GlnThr: 2.111 ± 0.74
1.688GlnVal: 1.688 ± 0.188
0.422GlnTrp: 0.422 ± 0.382
1.266GlnTyr: 1.266 ± 1.021
0.0GlnXaa: 0.0 ± 0.0
Arg
3.799ArgAla: 3.799 ± 0.519
1.688ArgCys: 1.688 ± 1.024
0.422ArgAsp: 0.422 ± 0.382
2.111ArgGlu: 2.111 ± 0.747
2.111ArgPhe: 2.111 ± 0.855
8.864ArgGly: 8.864 ± 2.62
1.266ArgHis: 1.266 ± 0.692
2.533ArgIle: 2.533 ± 0.953
2.955ArgLys: 2.955 ± 1.224
4.643ArgLeu: 4.643 ± 1.335
0.422ArgMet: 0.422 ± 0.382
0.844ArgAsn: 0.844 ± 0.765
5.065ArgPro: 5.065 ± 1.956
2.955ArgGln: 2.955 ± 1.16
7.176ArgArg: 7.176 ± 2.257
3.799ArgSer: 3.799 ± 1.252
5.91ArgThr: 5.91 ± 1.896
5.065ArgVal: 5.065 ± 1.093
0.422ArgTrp: 0.422 ± 0.382
4.221ArgTyr: 4.221 ± 1.282
0.0ArgXaa: 0.0 ± 0.0
Ser
2.955SerAla: 2.955 ± 1.114
2.111SerCys: 2.111 ± 1.261
5.91SerAsp: 5.91 ± 0.82
1.266SerGlu: 1.266 ± 0.439
2.111SerPhe: 2.111 ± 1.131
7.598SerGly: 7.598 ± 2.125
0.844SerHis: 0.844 ± 0.423
2.111SerIle: 2.111 ± 0.789
1.688SerLys: 1.688 ± 0.846
7.176SerLeu: 7.176 ± 1.235
1.266SerMet: 1.266 ± 0.347
2.111SerAsn: 2.111 ± 0.921
5.91SerPro: 5.91 ± 1.181
2.111SerGln: 2.111 ± 0.734
5.488SerArg: 5.488 ± 1.67
4.643SerSer: 4.643 ± 0.955
5.488SerThr: 5.488 ± 1.407
7.176SerVal: 7.176 ± 2.099
1.266SerTrp: 1.266 ± 0.712
0.844SerTyr: 0.844 ± 0.441
0.0SerXaa: 0.0 ± 0.0
Thr
3.799ThrAla: 3.799 ± 1.704
1.266ThrCys: 1.266 ± 0.748
5.488ThrAsp: 5.488 ± 1.531
1.266ThrGlu: 1.266 ± 0.731
1.688ThrPhe: 1.688 ± 0.615
8.02ThrGly: 8.02 ± 1.882
0.422ThrHis: 0.422 ± 0.398
1.266ThrIle: 1.266 ± 0.678
1.266ThrLys: 1.266 ± 0.75
7.176ThrLeu: 7.176 ± 1.831
1.266ThrMet: 1.266 ± 0.666
1.688ThrAsn: 1.688 ± 0.188
6.332ThrPro: 6.332 ± 1.192
1.266ThrGln: 1.266 ± 0.75
5.065ThrArg: 5.065 ± 1.826
5.91ThrSer: 5.91 ± 1.909
5.065ThrThr: 5.065 ± 0.835
6.754ThrVal: 6.754 ± 0.989
1.266ThrTrp: 1.266 ± 0.689
1.266ThrTyr: 1.266 ± 0.347
0.0ThrXaa: 0.0 ± 0.0
Val
1.266ValAla: 1.266 ± 0.75
2.955ValCys: 2.955 ± 1.286
4.643ValAsp: 4.643 ± 1.94
4.643ValGlu: 4.643 ± 1.14
3.799ValPhe: 3.799 ± 0.691
6.332ValGly: 6.332 ± 1.483
2.111ValHis: 2.111 ± 0.698
2.111ValIle: 2.111 ± 0.758
1.688ValLys: 1.688 ± 1.529
5.065ValLeu: 5.065 ± 0.789
0.0ValMet: 0.0 ± 0.0
1.266ValAsn: 1.266 ± 0.417
5.065ValPro: 5.065 ± 1.663
1.688ValGln: 1.688 ± 1.061
4.643ValArg: 4.643 ± 2.586
6.754ValSer: 6.754 ± 0.887
5.488ValThr: 5.488 ± 1.682
4.643ValVal: 4.643 ± 0.929
0.844ValTrp: 0.844 ± 0.442
2.955ValTyr: 2.955 ± 0.834
0.0ValXaa: 0.0 ± 0.0
Trp
1.266TrpAla: 1.266 ± 0.384
0.422TrpCys: 0.422 ± 0.379
0.844TrpAsp: 0.844 ± 0.423
0.844TrpGlu: 0.844 ± 0.423
0.422TrpPhe: 0.422 ± 0.379
0.844TrpGly: 0.844 ± 0.423
0.422TrpHis: 0.422 ± 0.379
0.844TrpIle: 0.844 ± 0.765
1.688TrpLys: 1.688 ± 0.734
1.688TrpLeu: 1.688 ± 0.846
0.0TrpMet: 0.0 ± 0.0
0.422TrpAsn: 0.422 ± 0.34
0.422TrpPro: 0.422 ± 0.379
0.844TrpGln: 0.844 ± 0.441
0.422TrpArg: 0.422 ± 0.382
1.688TrpSer: 1.688 ± 0.578
1.688TrpThr: 1.688 ± 1.26
0.844TrpVal: 0.844 ± 0.765
0.0TrpTrp: 0.0 ± 0.0
0.844TrpTyr: 0.844 ± 0.551
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.111TyrAla: 2.111 ± 1.011
0.422TyrCys: 0.422 ± 0.534
2.955TyrAsp: 2.955 ± 0.727
1.688TyrGlu: 1.688 ± 0.547
0.844TyrPhe: 0.844 ± 0.681
5.488TyrGly: 5.488 ± 1.174
0.844TyrHis: 0.844 ± 0.442
1.266TyrIle: 1.266 ± 0.657
1.688TyrLys: 1.688 ± 0.582
2.533TyrLeu: 2.533 ± 0.725
0.0TyrMet: 0.0 ± 0.0
0.844TyrAsn: 0.844 ± 0.423
0.844TyrPro: 0.844 ± 0.442
0.844TyrGln: 0.844 ± 0.442
2.533TyrArg: 2.533 ± 0.887
0.844TyrSer: 0.844 ± 0.795
2.533TyrThr: 2.533 ± 0.577
2.111TyrVal: 2.111 ± 0.412
0.844TyrTrp: 0.844 ± 0.423
2.111TyrTyr: 2.111 ± 0.429
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2370 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski