Amino acid dipepetide frequency for Marmoricola solisilvae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.918AlaAla: 17.918 ± 0.162	0.97AlaCys: 0.97 ± 0.03	7.989AlaAsp: 7.989 ± 0.077	7.944AlaGlu: 7.944 ± 0.123	3.736AlaPhe: 3.736 ± 0.058	11.735AlaGly: 11.735 ± 0.117	2.421AlaHis: 2.421 ± 0.048	4.999AlaIle: 4.999 ± 0.066	3.443AlaLys: 3.443 ± 0.057	12.751AlaLeu: 12.751 ± 0.134	2.698AlaMet: 2.698 ± 0.053	2.597AlaAsn: 2.597 ± 0.059	5.855AlaPro: 5.855 ± 0.088	3.581AlaGln: 3.581 ± 0.059	8.06AlaArg: 8.06 ± 0.09	6.626AlaSer: 6.626 ± 0.071	7.461AlaThr: 7.461 ± 0.109	10.89AlaVal: 10.89 ± 0.115	1.795AlaTrp: 1.795 ± 0.038	2.514AlaTyr: 2.514 ± 0.046	0.0AlaXaa: 0.0 ± 0.0
Cys	0.881CysAla: 0.881 ± 0.028	0.077CysCys: 0.077 ± 0.009	0.462CysAsp: 0.462 ± 0.023	0.376CysGlu: 0.376 ± 0.019	0.262CysPhe: 0.262 ± 0.016	0.895CysGly: 0.895 ± 0.031	0.197CysHis: 0.197 ± 0.013	0.257CysIle: 0.257 ± 0.014	0.154CysLys: 0.154 ± 0.012	0.611CysLeu: 0.611 ± 0.024	0.114CysMet: 0.114 ± 0.009	0.163CysAsn: 0.163 ± 0.011	0.455CysPro: 0.455 ± 0.021	0.201CysGln: 0.201 ± 0.012	0.481CysArg: 0.481 ± 0.021	0.547CysSer: 0.547 ± 0.025	0.533CysThr: 0.533 ± 0.025	0.6CysVal: 0.6 ± 0.022	0.123CysTrp: 0.123 ± 0.011	0.154CysTyr: 0.154 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	7.539AspAla: 7.539 ± 0.085	0.412AspCys: 0.412 ± 0.021	3.811AspAsp: 3.811 ± 0.062	4.072AspGlu: 4.072 ± 0.073	1.819AspPhe: 1.819 ± 0.043	6.191AspGly: 6.191 ± 0.075	1.436AspHis: 1.436 ± 0.032	2.128AspIle: 2.128 ± 0.045	1.444AspLys: 1.444 ± 0.035	7.213AspLeu: 7.213 ± 0.077	0.848AspMet: 0.848 ± 0.027	1.176AspAsn: 1.176 ± 0.033	4.434AspPro: 4.434 ± 0.058	1.922AspGln: 1.922 ± 0.04	4.177AspArg: 4.177 ± 0.067	2.741AspSer: 2.741 ± 0.054	2.732AspThr: 2.732 ± 0.052	5.576AspVal: 5.576 ± 0.084	0.968AspTrp: 0.968 ± 0.03	1.162AspTyr: 1.162 ± 0.032	0.0AspXaa: 0.0 ± 0.0
Glu	6.833GluAla: 6.833 ± 0.105	0.316GluCys: 0.316 ± 0.017	3.153GluAsp: 3.153 ± 0.052	3.153GluGlu: 3.153 ± 0.069	1.594GluPhe: 1.594 ± 0.036	3.882GluGly: 3.882 ± 0.065	1.636GluHis: 1.636 ± 0.037	2.75GluIle: 2.75 ± 0.055	1.672GluLys: 1.672 ± 0.042	6.358GluLeu: 6.358 ± 0.099	1.042GluMet: 1.042 ± 0.028	1.268GluAsn: 1.268 ± 0.034	2.976GluPro: 2.976 ± 0.062	2.146GluGln: 2.146 ± 0.046	4.538GluArg: 4.538 ± 0.077	2.684GluSer: 2.684 ± 0.046	2.912GluThr: 2.912 ± 0.055	5.106GluVal: 5.106 ± 0.074	0.676GluTrp: 0.676 ± 0.025	1.122GluTyr: 1.122 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	3.758PheAla: 3.758 ± 0.064	0.276PheCys: 0.276 ± 0.015	2.298PheAsp: 2.298 ± 0.046	1.686PheGlu: 1.686 ± 0.04	0.999PhePhe: 0.999 ± 0.033	3.395PheGly: 3.395 ± 0.057	0.595PheHis: 0.595 ± 0.022	0.979PheIle: 0.979 ± 0.027	0.724PheLys: 0.724 ± 0.024	2.738PheLeu: 2.738 ± 0.052	0.454PheMet: 0.454 ± 0.019	0.796PheAsn: 0.796 ± 0.03	1.35PhePro: 1.35 ± 0.034	0.704PheGln: 0.704 ± 0.023	1.703PheArg: 1.703 ± 0.043	1.854PheSer: 1.854 ± 0.042	2.26PheThr: 2.26 ± 0.049	2.7PheVal: 2.7 ± 0.052	0.451PheTrp: 0.451 ± 0.02	0.64PheTyr: 0.64 ± 0.022	0.0PheXaa: 0.0 ± 0.0
Gly	9.964GlyAla: 9.964 ± 0.106	0.884GlyCys: 0.884 ± 0.029	5.333GlyAsp: 5.333 ± 0.078	4.706GlyGlu: 4.706 ± 0.076	3.18GlyPhe: 3.18 ± 0.052	8.07GlyGly: 8.07 ± 0.134	2.077GlyHis: 2.077 ± 0.044	4.195GlyIle: 4.195 ± 0.064	2.776GlyLys: 2.776 ± 0.051	9.24GlyLeu: 9.24 ± 0.106	2.041GlyMet: 2.041 ± 0.035	2.212GlyAsn: 2.212 ± 0.064	4.278GlyPro: 4.278 ± 0.063	2.751GlyGln: 2.751 ± 0.053	5.979GlyArg: 5.979 ± 0.081	6.224GlySer: 6.224 ± 0.093	6.318GlyThr: 6.318 ± 0.111	7.787GlyVal: 7.787 ± 0.088	1.56GlyTrp: 1.56 ± 0.039	2.314GlyTyr: 2.314 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	2.402HisAla: 2.402 ± 0.048	0.166HisCys: 0.166 ± 0.012	1.392HisAsp: 1.392 ± 0.035	1.222HisGlu: 1.222 ± 0.029	0.647HisPhe: 0.647 ± 0.023	2.217HisGly: 2.217 ± 0.044	0.637HisHis: 0.637 ± 0.024	0.637HisIle: 0.637 ± 0.023	0.38HisLys: 0.38 ± 0.019	2.278HisLeu: 2.278 ± 0.041	0.303HisMet: 0.303 ± 0.017	0.416HisAsn: 0.416 ± 0.02	1.472HisPro: 1.472 ± 0.039	0.702HisGln: 0.702 ± 0.026	1.652HisArg: 1.652 ± 0.036	0.987HisSer: 0.987 ± 0.028	1.133HisThr: 1.133 ± 0.033	1.85HisVal: 1.85 ± 0.041	0.334HisTrp: 0.334 ± 0.015	0.463HisTyr: 0.463 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	5.853IleAla: 5.853 ± 0.072	0.342IleCys: 0.342 ± 0.018	2.933IleAsp: 2.933 ± 0.052	2.589IleGlu: 2.589 ± 0.053	1.034IlePhe: 1.034 ± 0.033	4.376IleGly: 4.376 ± 0.071	0.676IleHis: 0.676 ± 0.028	1.251IleIle: 1.251 ± 0.034	1.123IleLys: 1.123 ± 0.036	3.06IleLeu: 3.06 ± 0.057	0.558IleMet: 0.558 ± 0.021	1.102IleAsn: 1.102 ± 0.032	2.156IlePro: 2.156 ± 0.045	0.939IleGln: 0.939 ± 0.026	2.52IleArg: 2.52 ± 0.051	2.474IleSer: 2.474 ± 0.051	2.877IleThr: 2.877 ± 0.061	3.531IleVal: 3.531 ± 0.054	0.48IleTrp: 0.48 ± 0.019	0.724IleTyr: 0.724 ± 0.022	0.0IleXaa: 0.0 ± 0.0
Lys	3.547LysAla: 3.547 ± 0.058	0.132LysCys: 0.132 ± 0.01	1.533LysAsp: 1.533 ± 0.037	1.18LysGlu: 1.18 ± 0.034	0.661LysPhe: 0.661 ± 0.025	2.017LysGly: 2.017 ± 0.042	0.61LysHis: 0.61 ± 0.023	1.19LysIle: 1.19 ± 0.03	1.145LysLys: 1.145 ± 0.057	2.418LysLeu: 2.418 ± 0.047	0.508LysMet: 0.508 ± 0.021	0.786LysAsn: 0.786 ± 0.027	1.631LysPro: 1.631 ± 0.038	0.873LysGln: 0.873 ± 0.026	1.664LysArg: 1.664 ± 0.037	1.489LysSer: 1.489 ± 0.033	1.643LysThr: 1.643 ± 0.04	2.678LysVal: 2.678 ± 0.05	0.289LysTrp: 0.289 ± 0.015	0.638LysTyr: 0.638 ± 0.023	0.0LysXaa: 0.0 ± 0.0
Leu	13.989LeuAla: 13.989 ± 0.139	0.721LeuCys: 0.721 ± 0.023	6.796LeuAsp: 6.796 ± 0.082	5.395LeuGlu: 5.395 ± 0.08	2.634LeuPhe: 2.634 ± 0.055	9.488LeuGly: 9.488 ± 0.107	2.035LeuHis: 2.035 ± 0.046	3.848LeuIle: 3.848 ± 0.065	2.43LeuLys: 2.43 ± 0.046	9.942LeuLeu: 9.942 ± 0.121	1.634LeuMet: 1.634 ± 0.04	2.17LeuAsn: 2.17 ± 0.044	5.505LeuPro: 5.505 ± 0.071	2.359LeuGln: 2.359 ± 0.046	6.772LeuArg: 6.772 ± 0.093	5.424LeuSer: 5.424 ± 0.073	6.491LeuThr: 6.491 ± 0.078	9.807LeuVal: 9.807 ± 0.106	1.108LeuTrp: 1.108 ± 0.03	1.555LeuTyr: 1.555 ± 0.04	0.001LeuXaa: 0.001 ± 0.001
Met	2.195MetAla: 2.195 ± 0.043	0.129MetCys: 0.129 ± 0.011	0.87MetAsp: 0.87 ± 0.027	0.747MetGlu: 0.747 ± 0.028	0.575MetPhe: 0.575 ± 0.025	1.444MetGly: 1.444 ± 0.037	0.404MetHis: 0.404 ± 0.019	0.813MetIle: 0.813 ± 0.026	0.59MetLys: 0.59 ± 0.022	1.833MetLeu: 1.833 ± 0.039	0.393MetMet: 0.393 ± 0.02	0.512MetAsn: 0.512 ± 0.022	1.137MetPro: 1.137 ± 0.031	0.508MetGln: 0.508 ± 0.019	1.401MetArg: 1.401 ± 0.034	1.531MetSer: 1.531 ± 0.035	1.736MetThr: 1.736 ± 0.039	1.564MetVal: 1.564 ± 0.037	0.198MetTrp: 0.198 ± 0.014	0.312MetTyr: 0.312 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	2.871AsnAla: 2.871 ± 0.059	0.178AsnCys: 0.178 ± 0.013	1.294AsnAsp: 1.294 ± 0.038	1.095AsnGlu: 1.095 ± 0.028	0.688AsnPhe: 0.688 ± 0.026	2.413AsnGly: 2.413 ± 0.067	0.489AsnHis: 0.489 ± 0.019	0.887AsnIle: 0.887 ± 0.028	0.654AsnLys: 0.654 ± 0.026	2.333AsnLeu: 2.333 ± 0.052	0.362AsnMet: 0.362 ± 0.017	0.657AsnAsn: 0.657 ± 0.035	1.752AsnPro: 1.752 ± 0.052	0.747AsnGln: 0.747 ± 0.031	1.36AsnArg: 1.36 ± 0.033	1.173AsnSer: 1.173 ± 0.042	1.43AsnThr: 1.43 ± 0.042	1.922AsnVal: 1.922 ± 0.045	0.307AsnTrp: 0.307 ± 0.017	0.517AsnTyr: 0.517 ± 0.022	0.0AsnXaa: 0.0 ± 0.0
Pro	6.776ProAla: 6.776 ± 0.086	0.295ProCys: 0.295 ± 0.016	3.971ProAsp: 3.971 ± 0.054	3.764ProGlu: 3.764 ± 0.058	1.554ProPhe: 1.554 ± 0.033	5.507ProGly: 5.507 ± 0.075	1.059ProHis: 1.059 ± 0.027	2.007ProIle: 2.007 ± 0.045	1.463ProLys: 1.463 ± 0.039	4.549ProLeu: 4.549 ± 0.073	1.039ProMet: 1.039 ± 0.029	1.228ProAsn: 1.228 ± 0.038	2.522ProPro: 2.522 ± 0.055	1.458ProGln: 1.458 ± 0.035	3.02ProArg: 3.02 ± 0.058	3.105ProSer: 3.105 ± 0.06	3.684ProThr: 3.684 ± 0.071	4.983ProVal: 4.983 ± 0.075	0.817ProTrp: 0.817 ± 0.028	1.171ProTyr: 1.171 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	3.699GlnAla: 3.699 ± 0.054	0.179GlnCys: 0.179 ± 0.012	1.347GlnAsp: 1.347 ± 0.038	1.196GlnGlu: 1.196 ± 0.036	0.868GlnPhe: 0.868 ± 0.027	2.132GlnGly: 2.132 ± 0.046	0.703GlnHis: 0.703 ± 0.026	1.383GlnIle: 1.383 ± 0.032	0.769GlnLys: 0.769 ± 0.03	3.127GlnLeu: 3.127 ± 0.06	0.596GlnMet: 0.596 ± 0.019	0.657GlnAsn: 0.657 ± 0.022	1.592GlnPro: 1.592 ± 0.039	1.171GlnGln: 1.171 ± 0.037	2.269GlnArg: 2.269 ± 0.046	1.303GlnSer: 1.303 ± 0.036	1.551GlnThr: 1.551 ± 0.036	2.915GlnVal: 2.915 ± 0.059	0.398GlnTrp: 0.398 ± 0.017	0.609GlnTyr: 0.609 ± 0.02	0.0GlnXaa: 0.0 ± 0.0
Arg	7.571ArgAla: 7.571 ± 0.089	0.44ArgCys: 0.44 ± 0.023	3.793ArgAsp: 3.793 ± 0.063	3.907ArgGlu: 3.907 ± 0.068	2.261ArgPhe: 2.261 ± 0.049	4.837ArgGly: 4.837 ± 0.064	1.466ArgHis: 1.466 ± 0.04	3.337ArgIle: 3.337 ± 0.054	1.687ArgLys: 1.687 ± 0.039	7.066ArgLeu: 7.066 ± 0.105	1.711ArgMet: 1.711 ± 0.035	1.445ArgAsn: 1.445 ± 0.036	3.399ArgPro: 3.399 ± 0.06	1.831ArgGln: 1.831 ± 0.04	5.746ArgArg: 5.746 ± 0.101	3.958ArgSer: 3.958 ± 0.065	4.468ArgThr: 4.468 ± 0.068	5.38ArgVal: 5.38 ± 0.076	1.233ArgTrp: 1.233 ± 0.03	1.508ArgTyr: 1.508 ± 0.032	0.001ArgXaa: 0.001 ± 0.001
Ser	6.861SerAla: 6.861 ± 0.084	0.479SerCys: 0.479 ± 0.024	3.182SerAsp: 3.182 ± 0.053	2.661SerGlu: 2.661 ± 0.048	1.902SerPhe: 1.902 ± 0.041	6.292SerGly: 6.292 ± 0.106	0.993SerHis: 0.993 ± 0.024	2.324SerIle: 2.324 ± 0.047	1.463SerLys: 1.463 ± 0.032	5.218SerLeu: 5.218 ± 0.067	1.347SerMet: 1.347 ± 0.037	1.34SerAsn: 1.34 ± 0.037	2.978SerPro: 2.978 ± 0.055	1.528SerGln: 1.528 ± 0.037	3.527SerArg: 3.527 ± 0.06	3.806SerSer: 3.806 ± 0.07	4.018SerThr: 4.018 ± 0.079	4.77SerVal: 4.77 ± 0.069	0.96SerTrp: 0.96 ± 0.033	1.457SerTyr: 1.457 ± 0.039	0.0SerXaa: 0.0 ± 0.0
Thr	7.793ThrAla: 7.793 ± 0.097	0.56ThrCys: 0.56 ± 0.022	3.621ThrAsp: 3.621 ± 0.06	3.12ThrGlu: 3.12 ± 0.059	2.127ThrPhe: 2.127 ± 0.053	6.474ThrGly: 6.474 ± 0.093	1.191ThrHis: 1.191 ± 0.037	2.628ThrIle: 2.628 ± 0.053	1.671ThrLys: 1.671 ± 0.042	5.869ThrLeu: 5.869 ± 0.074	1.113ThrMet: 1.113 ± 0.029	1.514ThrAsn: 1.514 ± 0.042	3.891ThrPro: 3.891 ± 0.069	1.643ThrGln: 1.643 ± 0.04	3.627ThrArg: 3.627 ± 0.064	4.066ThrSer: 4.066 ± 0.088	4.411ThrThr: 4.411 ± 0.08	5.917ThrVal: 5.917 ± 0.09	1.119ThrTrp: 1.119 ± 0.034	1.598ThrTyr: 1.598 ± 0.044	0.0ThrXaa: 0.0 ± 0.0
Val	11.358ValAla: 11.358 ± 0.108	0.692ValCys: 0.692 ± 0.026	5.644ValAsp: 5.644 ± 0.069	5.315ValGlu: 5.315 ± 0.07	2.537ValPhe: 2.537 ± 0.05	7.491ValGly: 7.491 ± 0.086	1.938ValHis: 1.938 ± 0.043	3.838ValIle: 3.838 ± 0.059	2.151ValLys: 2.151 ± 0.043	9.683ValLeu: 9.683 ± 0.11	1.571ValMet: 1.571 ± 0.031	2.14ValAsn: 2.14 ± 0.051	4.849ValPro: 4.849 ± 0.075	2.264ValGln: 2.264 ± 0.041	6.03ValArg: 6.03 ± 0.09	4.903ValSer: 4.903 ± 0.078	6.089ValThr: 6.089 ± 0.082	9.168ValVal: 9.168 ± 0.108	0.993ValTrp: 0.993 ± 0.03	1.51ValTyr: 1.51 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	1.503TrpAla: 1.503 ± 0.036	0.13TrpCys: 0.13 ± 0.011	0.809TrpAsp: 0.809 ± 0.027	0.635TrpGlu: 0.635 ± 0.025	0.541TrpPhe: 0.541 ± 0.022	1.026TrpGly: 1.026 ± 0.029	0.375TrpHis: 0.375 ± 0.018	0.604TrpIle: 0.604 ± 0.024	0.426TrpLys: 0.426 ± 0.021	1.622TrpLeu: 1.622 ± 0.038	0.323TrpMet: 0.323 ± 0.016	0.447TrpAsn: 0.447 ± 0.022	0.682TrpPro: 0.682 ± 0.025	0.508TrpGln: 0.508 ± 0.021	1.021TrpArg: 1.021 ± 0.03	1.042TrpSer: 1.042 ± 0.032	0.997TrpThr: 0.997 ± 0.034	1.166TrpVal: 1.166 ± 0.033	0.329TrpTrp: 0.329 ± 0.016	0.312TrpTyr: 0.312 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.671TyrAla: 2.671 ± 0.048	0.165TyrCys: 0.165 ± 0.011	1.568TyrAsp: 1.568 ± 0.039	1.057TyrGlu: 1.057 ± 0.032	0.739TyrPhe: 0.739 ± 0.026	2.009TyrGly: 2.009 ± 0.036	0.352TyrHis: 0.352 ± 0.018	0.543TyrIle: 0.543 ± 0.022	0.468TyrLys: 0.468 ± 0.021	2.195TyrLeu: 2.195 ± 0.047	0.238TyrMet: 0.238 ± 0.014	0.503TyrAsn: 0.503 ± 0.024	1.059TyrPro: 1.059 ± 0.031	0.626TyrGln: 0.626 ± 0.02	1.497TyrArg: 1.497 ± 0.037	1.169TyrSer: 1.169 ± 0.042	1.207TyrThr: 1.207 ± 0.041	1.856TyrVal: 1.856 ± 0.038	0.358TyrTrp: 0.358 ± 0.018	0.471TyrTyr: 0.471 ± 0.023	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.001	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.001XaaSer: 0.001 ± 0.001	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3726 proteins (1174687 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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