Amino acid dipepetide frequency for Colletotrichum fructicola (strain Nara gc5) (Anthracnose fungus) (Colletotrichum gloeosporioides (strain Nara gc5))

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.421AlaAla: 10.421 ± 0.064
1.2AlaCys: 1.2 ± 0.013
4.68AlaAsp: 4.68 ± 0.027
5.353AlaGlu: 5.353 ± 0.037
3.36AlaPhe: 3.36 ± 0.023
6.321AlaGly: 6.321 ± 0.032
1.716AlaHis: 1.716 ± 0.015
4.404AlaIle: 4.404 ± 0.03
4.24AlaLys: 4.24 ± 0.027
7.917AlaLeu: 7.917 ± 0.039
2.168AlaMet: 2.168 ± 0.019
3.147AlaAsn: 3.147 ± 0.024
5.004AlaPro: 5.004 ± 0.046
3.403AlaGln: 3.403 ± 0.022
4.858AlaArg: 4.858 ± 0.029
7.37AlaSer: 7.37 ± 0.047
5.635AlaThr: 5.635 ± 0.034
5.912AlaVal: 5.912 ± 0.033
1.348AlaTrp: 1.348 ± 0.013
2.3AlaTyr: 2.3 ± 0.02
0.0AlaXaa: 0.0 ± 0.0
Cys
1.002CysAla: 1.002 ± 0.012
0.272CysCys: 0.272 ± 0.007
0.742CysAsp: 0.742 ± 0.01
0.627CysGlu: 0.627 ± 0.01
0.562CysPhe: 0.562 ± 0.009
1.022CysGly: 1.022 ± 0.011
0.333CysHis: 0.333 ± 0.006
0.727CysIle: 0.727 ± 0.009
0.537CysLys: 0.537 ± 0.009
1.275CysLeu: 1.275 ± 0.013
0.295CysMet: 0.295 ± 0.007
0.471CysAsn: 0.471 ± 0.008
0.695CysPro: 0.695 ± 0.011
0.472CysGln: 0.472 ± 0.008
0.778CysArg: 0.778 ± 0.011
0.94CysSer: 0.94 ± 0.012
0.722CysThr: 0.722 ± 0.011
0.848CysVal: 0.848 ± 0.011
0.24CysTrp: 0.24 ± 0.005
0.375CysTyr: 0.375 ± 0.008
0.0CysXaa: 0.0 ± 0.0
Asp
5.096AspAla: 5.096 ± 0.029
0.693AspCys: 0.693 ± 0.01
4.499AspAsp: 4.499 ± 0.035
4.49AspGlu: 4.49 ± 0.031
2.362AspPhe: 2.362 ± 0.021
4.447AspGly: 4.447 ± 0.029
1.252AspHis: 1.252 ± 0.013
2.968AspIle: 2.968 ± 0.02
2.479AspLys: 2.479 ± 0.02
5.074AspLeu: 5.074 ± 0.028
1.302AspMet: 1.302 ± 0.012
1.969AspAsn: 1.969 ± 0.017
3.303AspPro: 3.303 ± 0.02
1.823AspGln: 1.823 ± 0.018
3.024AspArg: 3.024 ± 0.029
3.914AspSer: 3.914 ± 0.028
2.956AspThr: 2.956 ± 0.019
3.927AspVal: 3.927 ± 0.024
0.991AspTrp: 0.991 ± 0.011
1.62AspTyr: 1.62 ± 0.016
0.0AspXaa: 0.0 ± 0.0
Glu
5.648GluAla: 5.648 ± 0.035
0.636GluCys: 0.636 ± 0.01
4.162GluAsp: 4.162 ± 0.03
5.129GluGlu: 5.129 ± 0.05
1.938GluPhe: 1.938 ± 0.015
3.772GluGly: 3.772 ± 0.021
1.364GluHis: 1.364 ± 0.015
2.915GluIle: 2.915 ± 0.021
3.648GluLys: 3.648 ± 0.029
4.934GluLeu: 4.934 ± 0.029
1.488GluMet: 1.488 ± 0.014
2.213GluAsn: 2.213 ± 0.018
2.827GluPro: 2.827 ± 0.032
2.273GluGln: 2.273 ± 0.021
3.726GluArg: 3.726 ± 0.031
3.964GluSer: 3.964 ± 0.024
3.507GluThr: 3.507 ± 0.027
3.683GluVal: 3.683 ± 0.023
0.954GluTrp: 0.954 ± 0.01
1.634GluTyr: 1.634 ± 0.016
0.0GluXaa: 0.0 ± 0.0
Phe
3.3PheAla: 3.3 ± 0.028
0.605PheCys: 0.605 ± 0.011
2.403PheAsp: 2.403 ± 0.018
2.213PheGlu: 2.213 ± 0.019
1.728PhePhe: 1.728 ± 0.018
3.025PheGly: 3.025 ± 0.022
0.928PheHis: 0.928 ± 0.012
1.859PheIle: 1.859 ± 0.017
1.574PheLys: 1.574 ± 0.015
3.474PheLeu: 3.474 ± 0.023
0.855PheMet: 0.855 ± 0.01
1.517PheAsn: 1.517 ± 0.015
1.983PhePro: 1.983 ± 0.018
1.419PheGln: 1.419 ± 0.011
2.008PheArg: 2.008 ± 0.016
2.959PheSer: 2.959 ± 0.018
2.235PheThr: 2.235 ± 0.017
2.519PheVal: 2.519 ± 0.02
0.714PheTrp: 0.714 ± 0.01
1.151PheTyr: 1.151 ± 0.014
0.0PheXaa: 0.0 ± 0.0
Gly
5.839GlyAla: 5.839 ± 0.035
0.985GlyCys: 0.985 ± 0.013
3.799GlyAsp: 3.799 ± 0.026
3.517GlyGlu: 3.517 ± 0.024
2.995GlyPhe: 2.995 ± 0.022
6.172GlyGly: 6.172 ± 0.049
1.733GlyHis: 1.733 ± 0.017
3.601GlyIle: 3.601 ± 0.022
3.452GlyLys: 3.452 ± 0.022
6.27GlyLeu: 6.27 ± 0.034
1.693GlyMet: 1.693 ± 0.018
2.677GlyAsn: 2.677 ± 0.022
3.452GlyPro: 3.452 ± 0.026
2.563GlyGln: 2.563 ± 0.023
4.162GlyArg: 4.162 ± 0.026
5.664GlySer: 5.664 ± 0.033
4.186GlyThr: 4.186 ± 0.039
4.676GlyVal: 4.676 ± 0.03
1.304GlyTrp: 1.304 ± 0.015
2.2GlyTyr: 2.2 ± 0.021
0.0GlyXaa: 0.0 ± 0.0
His
1.819HisAla: 1.819 ± 0.02
0.343HisCys: 0.343 ± 0.008
1.32HisAsp: 1.32 ± 0.013
1.292HisGlu: 1.292 ± 0.012
0.951HisPhe: 0.951 ± 0.011
1.721HisGly: 1.721 ± 0.017
0.84HisHis: 0.84 ± 0.013
1.156HisIle: 1.156 ± 0.012
0.915HisLys: 0.915 ± 0.012
2.167HisLeu: 2.167 ± 0.02
0.522HisMet: 0.522 ± 0.009
0.826HisAsn: 0.826 ± 0.011
1.561HisPro: 1.561 ± 0.015
0.964HisGln: 0.964 ± 0.013
1.469HisArg: 1.469 ± 0.015
1.642HisSer: 1.642 ± 0.015
1.198HisThr: 1.198 ± 0.013
1.463HisVal: 1.463 ± 0.013
0.37HisTrp: 0.37 ± 0.006
0.676HisTyr: 0.676 ± 0.01
0.0HisXaa: 0.0 ± 0.0
Ile
4.285IleAla: 4.285 ± 0.025
0.741IleCys: 0.741 ± 0.01
2.882IleAsp: 2.882 ± 0.021
2.724IleGlu: 2.724 ± 0.019
2.008IlePhe: 2.008 ± 0.02
3.301IleGly: 3.301 ± 0.026
1.177IleHis: 1.177 ± 0.013
2.557IleIle: 2.557 ± 0.025
2.139IleLys: 2.139 ± 0.018
4.37IleLeu: 4.37 ± 0.03
1.073IleMet: 1.073 ± 0.012
1.804IleAsn: 1.804 ± 0.017
2.897IlePro: 2.897 ± 0.022
1.835IleGln: 1.835 ± 0.016
2.72IleArg: 2.72 ± 0.019
3.611IleSer: 3.611 ± 0.027
2.894IleThr: 2.894 ± 0.026
3.236IleVal: 3.236 ± 0.021
0.795IleTrp: 0.795 ± 0.012
1.357IleTyr: 1.357 ± 0.013
0.0IleXaa: 0.0 ± 0.0
Lys
4.446LysAla: 4.446 ± 0.029
0.516LysCys: 0.516 ± 0.007
2.883LysAsp: 2.883 ± 0.022
3.26LysGlu: 3.26 ± 0.026
1.505LysPhe: 1.505 ± 0.014
3.045LysGly: 3.045 ± 0.021
1.11LysHis: 1.11 ± 0.012
2.205LysIle: 2.205 ± 0.019
3.216LysLys: 3.216 ± 0.038
4.011LysLeu: 4.011 ± 0.024
1.048LysMet: 1.048 ± 0.012
1.722LysAsn: 1.722 ± 0.018
2.715LysPro: 2.715 ± 0.023
1.76LysGln: 1.76 ± 0.019
3.149LysArg: 3.149 ± 0.024
3.324LysSer: 3.324 ± 0.024
2.958LysThr: 2.958 ± 0.02
2.859LysVal: 2.859 ± 0.022
0.726LysTrp: 0.726 ± 0.011
1.379LysTyr: 1.379 ± 0.014
0.0LysXaa: 0.0 ± 0.0
Leu
8.073LeuAla: 8.073 ± 0.041
1.23LeuCys: 1.23 ± 0.014
5.111LeuAsp: 5.111 ± 0.03
5.252LeuGlu: 5.252 ± 0.031
3.341LeuPhe: 3.341 ± 0.023
6.116LeuGly: 6.116 ± 0.035
2.138LeuHis: 2.138 ± 0.016
3.794LeuIle: 3.794 ± 0.026
4.077LeuLys: 4.077 ± 0.026
8.044LeuLeu: 8.044 ± 0.041
1.843LeuMet: 1.843 ± 0.016
3.064LeuAsn: 3.064 ± 0.023
5.379LeuPro: 5.379 ± 0.036
3.61LeuGln: 3.61 ± 0.023
5.64LeuArg: 5.64 ± 0.034
6.836LeuSer: 6.836 ± 0.033
4.749LeuThr: 4.749 ± 0.029
5.517LeuVal: 5.517 ± 0.029
1.347LeuTrp: 1.347 ± 0.015
2.304LeuTyr: 2.304 ± 0.018
0.0LeuXaa: 0.0 ± 0.0
Met
2.39MetAla: 2.39 ± 0.019
0.268MetCys: 0.268 ± 0.006
1.295MetAsp: 1.295 ± 0.012
1.32MetGlu: 1.32 ± 0.013
0.827MetPhe: 0.827 ± 0.01
1.52MetGly: 1.52 ± 0.017
0.494MetHis: 0.494 ± 0.009
1.035MetIle: 1.035 ± 0.013
1.057MetLys: 1.057 ± 0.011
1.891MetLeu: 1.891 ± 0.014
0.645MetMet: 0.645 ± 0.01
0.834MetAsn: 0.834 ± 0.011
1.305MetPro: 1.305 ± 0.013
0.821MetGln: 0.821 ± 0.01
1.333MetArg: 1.333 ± 0.013
1.897MetSer: 1.897 ± 0.016
1.385MetThr: 1.385 ± 0.015
1.38MetVal: 1.38 ± 0.013
0.309MetTrp: 0.309 ± 0.006
0.556MetTyr: 0.556 ± 0.01
0.0MetXaa: 0.0 ± 0.0
Asn
3.208AsnAla: 3.208 ± 0.023
0.491AsnCys: 0.491 ± 0.008
2.056AsnAsp: 2.056 ± 0.018
1.955AsnGlu: 1.955 ± 0.017
1.459AsnPhe: 1.459 ± 0.014
3.125AsnGly: 3.125 ± 0.025
0.83AsnHis: 0.83 ± 0.011
2.012AsnIle: 2.012 ± 0.017
1.523AsnLys: 1.523 ± 0.015
3.202AsnLeu: 3.202 ± 0.022
0.885AsnMet: 0.885 ± 0.011
1.564AsnAsn: 1.564 ± 0.02
2.355AsnPro: 2.355 ± 0.018
1.31AsnGln: 1.31 ± 0.015
1.871AsnArg: 1.871 ± 0.015
2.581AsnSer: 2.581 ± 0.02
2.217AsnThr: 2.217 ± 0.015
2.366AsnVal: 2.366 ± 0.017
0.609AsnTrp: 0.609 ± 0.008
1.076AsnTyr: 1.076 ± 0.013
0.0AsnXaa: 0.0 ± 0.0
Pro
5.615ProAla: 5.615 ± 0.05
0.534ProCys: 0.534 ± 0.009
3.285ProAsp: 3.285 ± 0.02
3.929ProGlu: 3.929 ± 0.031
2.087ProPhe: 2.087 ± 0.017
4.036ProGly: 4.036 ± 0.029
1.215ProHis: 1.215 ± 0.013
2.478ProIle: 2.478 ± 0.017
2.691ProLys: 2.691 ± 0.02
4.516ProLeu: 4.516 ± 0.028
1.094ProMet: 1.094 ± 0.015
2.158ProAsn: 2.158 ± 0.018
4.839ProPro: 4.839 ± 0.061
2.357ProGln: 2.357 ± 0.023
3.289ProArg: 3.289 ± 0.03
5.388ProSer: 5.388 ± 0.038
3.872ProThr: 3.872 ± 0.035
3.559ProVal: 3.559 ± 0.026
0.835ProTrp: 0.835 ± 0.01
1.486ProTyr: 1.486 ± 0.015
0.0ProXaa: 0.0 ± 0.0
Gln
3.493GlnAla: 3.493 ± 0.023
0.455GlnCys: 0.455 ± 0.008
2.006GlnAsp: 2.006 ± 0.016
2.272GlnGlu: 2.272 ± 0.018
1.237GlnPhe: 1.237 ± 0.013
2.384GlnGly: 2.384 ± 0.022
1.039GlnHis: 1.039 ± 0.014
1.777GlnIle: 1.777 ± 0.016
1.912GlnLys: 1.912 ± 0.017
3.327GlnLeu: 3.327 ± 0.024
0.914GlnMet: 0.914 ± 0.012
1.439GlnAsn: 1.439 ± 0.014
2.486GlnPro: 2.486 ± 0.026
2.385GlnGln: 2.385 ± 0.041
2.507GlnArg: 2.507 ± 0.019
2.819GlnSer: 2.819 ± 0.022
2.314GlnThr: 2.314 ± 0.019
2.142GlnVal: 2.142 ± 0.018
0.594GlnTrp: 0.594 ± 0.009
1.124GlnTyr: 1.124 ± 0.012
0.0GlnXaa: 0.0 ± 0.0
Arg
4.617ArgAla: 4.617 ± 0.026
0.741ArgCys: 0.741 ± 0.01
3.45ArgAsp: 3.45 ± 0.026
3.649ArgGlu: 3.649 ± 0.031
2.186ArgPhe: 2.186 ± 0.016
3.692ArgGly: 3.692 ± 0.03
1.531ArgHis: 1.531 ± 0.014
2.792ArgIle: 2.792 ± 0.022
3.246ArgLys: 3.246 ± 0.025
5.384ArgLeu: 5.384 ± 0.032
1.334ArgMet: 1.334 ± 0.013
2.175ArgAsn: 2.175 ± 0.016
3.398ArgPro: 3.398 ± 0.027
2.544ArgGln: 2.544 ± 0.02
4.916ArgArg: 4.916 ± 0.041
4.34ArgSer: 4.34 ± 0.03
3.137ArgThr: 3.137 ± 0.022
3.349ArgVal: 3.349 ± 0.023
1.012ArgTrp: 1.012 ± 0.012
1.64ArgTyr: 1.64 ± 0.015
0.0ArgXaa: 0.0 ± 0.0
Ser
6.603SerAla: 6.603 ± 0.043
0.901SerCys: 0.901 ± 0.014
4.133SerAsp: 4.133 ± 0.03
3.923SerGlu: 3.923 ± 0.024
3.058SerPhe: 3.058 ± 0.024
5.461SerGly: 5.461 ± 0.035
1.768SerHis: 1.768 ± 0.016
3.775SerIle: 3.775 ± 0.022
3.504SerLys: 3.504 ± 0.026
6.708SerLeu: 6.708 ± 0.031
1.728SerMet: 1.728 ± 0.018
2.837SerAsn: 2.837 ± 0.021
5.003SerPro: 5.003 ± 0.042
3.041SerGln: 3.041 ± 0.021
4.592SerArg: 4.592 ± 0.031
7.829SerSer: 7.829 ± 0.065
5.218SerThr: 5.218 ± 0.042
4.564SerVal: 4.564 ± 0.028
1.215SerTrp: 1.215 ± 0.014
2.018SerTyr: 2.018 ± 0.015
0.0SerXaa: 0.0 ± 0.0
Thr
5.591ThrAla: 5.591 ± 0.04
0.795ThrCys: 0.795 ± 0.011
2.907ThrAsp: 2.907 ± 0.022
3.131ThrGlu: 3.131 ± 0.021
2.307ThrPhe: 2.307 ± 0.018
4.318ThrGly: 4.318 ± 0.037
1.218ThrHis: 1.218 ± 0.013
3.123ThrIle: 3.123 ± 0.031
2.667ThrLys: 2.667 ± 0.019
5.103ThrLeu: 5.103 ± 0.036
1.217ThrMet: 1.217 ± 0.012
2.161ThrAsn: 2.161 ± 0.018
4.198ThrPro: 4.198 ± 0.031
2.068ThrGln: 2.068 ± 0.017
3.032ThrArg: 3.032 ± 0.021
5.125ThrSer: 5.125 ± 0.04
4.439ThrThr: 4.439 ± 0.053
3.879ThrVal: 3.879 ± 0.038
0.986ThrTrp: 0.986 ± 0.011
1.718ThrTyr: 1.718 ± 0.014
0.0ThrXaa: 0.0 ± 0.0
Val
5.757ValAla: 5.757 ± 0.03
0.87ValCys: 0.87 ± 0.012
3.836ValAsp: 3.836 ± 0.024
3.911ValGlu: 3.911 ± 0.023
2.679ValPhe: 2.679 ± 0.02
4.236ValGly: 4.236 ± 0.028
1.366ValHis: 1.366 ± 0.014
3.048ValIle: 3.048 ± 0.023
2.968ValLys: 2.968 ± 0.023
5.724ValLeu: 5.724 ± 0.034
1.402ValMet: 1.402 ± 0.014
2.288ValAsn: 2.288 ± 0.02
3.673ValPro: 3.673 ± 0.026
2.295ValGln: 2.295 ± 0.02
3.434ValArg: 3.434 ± 0.021
4.591ValSer: 4.591 ± 0.031
3.723ValThr: 3.723 ± 0.033
4.647ValVal: 4.647 ± 0.031
0.998ValTrp: 0.998 ± 0.013
1.792ValTyr: 1.792 ± 0.017
0.0ValXaa: 0.0 ± 0.0
Trp
1.32TrpAla: 1.32 ± 0.015
0.221TrpCys: 0.221 ± 0.005
1.0TrpAsp: 1.0 ± 0.013
0.916TrpGlu: 0.916 ± 0.01
0.639TrpPhe: 0.639 ± 0.011
1.05TrpGly: 1.05 ± 0.014
0.39TrpHis: 0.39 ± 0.008
0.825TrpIle: 0.825 ± 0.012
0.891TrpLys: 0.891 ± 0.011
1.467TrpLeu: 1.467 ± 0.016
0.421TrpMet: 0.421 ± 0.008
0.691TrpAsn: 0.691 ± 0.01
0.731TrpPro: 0.731 ± 0.01
0.62TrpGln: 0.62 ± 0.009
1.007TrpArg: 1.007 ± 0.011
1.131TrpSer: 1.131 ± 0.014
1.042TrpThr: 1.042 ± 0.013
1.0TrpVal: 1.0 ± 0.012
0.308TrpTrp: 0.308 ± 0.007
0.494TrpTyr: 0.494 ± 0.008
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.235TyrAla: 2.235 ± 0.019
0.435TyrCys: 0.435 ± 0.008
1.742TyrAsp: 1.742 ± 0.013
1.549TyrGlu: 1.549 ± 0.015
1.239TyrPhe: 1.239 ± 0.013
2.174TyrGly: 2.174 ± 0.017
0.775TyrHis: 0.775 ± 0.01
1.357TyrIle: 1.357 ± 0.014
1.105TyrLys: 1.105 ± 0.013
2.608TyrLeu: 2.608 ± 0.019
0.634TyrMet: 0.634 ± 0.008
1.141TyrAsn: 1.141 ± 0.014
1.458TyrPro: 1.458 ± 0.016
1.063TyrGln: 1.063 ± 0.012
1.618TyrArg: 1.618 ± 0.016
1.955TyrSer: 1.955 ± 0.017
1.593TyrThr: 1.593 ± 0.016
1.711TyrVal: 1.711 ± 0.015
0.507TyrTrp: 0.507 ± 0.008
0.931TyrTyr: 0.931 ± 0.013
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 17182 proteins (8073644 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski