Amino acid dipepetide frequency for Hubei picorna-like virus 38

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.411AlaAla: 4.411 ± 0.0
0.339AlaCys: 0.339 ± 0.0
2.715AlaAsp: 2.715 ± 0.0
2.715AlaGlu: 2.715 ± 0.0
2.036AlaPhe: 2.036 ± 0.0
4.072AlaGly: 4.072 ± 0.0
0.339AlaHis: 0.339 ± 0.0
2.036AlaIle: 2.036 ± 0.0
3.054AlaLys: 3.054 ± 0.0
7.805AlaLeu: 7.805 ± 0.0
2.375AlaMet: 2.375 ± 0.0
3.054AlaAsn: 3.054 ± 0.0
1.018AlaPro: 1.018 ± 0.0
1.018AlaGln: 1.018 ± 0.0
2.375AlaArg: 2.375 ± 0.0
3.393AlaSer: 3.393 ± 0.0
6.447AlaThr: 6.447 ± 0.0
3.733AlaVal: 3.733 ± 0.0
0.679AlaTrp: 0.679 ± 0.0
2.036AlaTyr: 2.036 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.679CysAla: 0.679 ± 0.0
0.339CysCys: 0.339 ± 0.0
0.679CysAsp: 0.679 ± 0.0
0.679CysGlu: 0.679 ± 0.0
0.0CysPhe: 0.0 ± 0.0
2.036CysGly: 2.036 ± 0.0
0.339CysHis: 0.339 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.357CysLys: 1.357 ± 0.0
1.018CysLeu: 1.018 ± 0.0
0.679CysMet: 0.679 ± 0.0
1.018CysAsn: 1.018 ± 0.0
1.018CysPro: 1.018 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.018CysArg: 1.018 ± 0.0
0.679CysSer: 0.679 ± 0.0
0.679CysThr: 0.679 ± 0.0
0.679CysVal: 0.679 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.697CysTyr: 1.697 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.036AspAla: 2.036 ± 0.0
0.0AspCys: 0.0 ± 0.0
3.393AspAsp: 3.393 ± 0.0
4.751AspGlu: 4.751 ± 0.0
2.715AspPhe: 2.715 ± 0.0
1.357AspGly: 1.357 ± 0.0
0.339AspHis: 0.339 ± 0.0
3.733AspIle: 3.733 ± 0.0
5.769AspLys: 5.769 ± 0.0
3.733AspLeu: 3.733 ± 0.0
1.357AspMet: 1.357 ± 0.0
2.375AspAsn: 2.375 ± 0.0
3.054AspPro: 3.054 ± 0.0
1.697AspGln: 1.697 ± 0.0
2.036AspArg: 2.036 ± 0.0
4.751AspSer: 4.751 ± 0.0
5.769AspThr: 5.769 ± 0.0
4.072AspVal: 4.072 ± 0.0
0.679AspTrp: 0.679 ± 0.0
4.072AspTyr: 4.072 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
2.715GluAla: 2.715 ± 0.0
0.339GluCys: 0.339 ± 0.0
3.733GluAsp: 3.733 ± 0.0
4.072GluGlu: 4.072 ± 0.0
2.375GluPhe: 2.375 ± 0.0
3.054GluGly: 3.054 ± 0.0
2.715GluHis: 2.715 ± 0.0
3.733GluIle: 3.733 ± 0.0
4.411GluLys: 4.411 ± 0.0
5.429GluLeu: 5.429 ± 0.0
1.357GluMet: 1.357 ± 0.0
2.036GluAsn: 2.036 ± 0.0
3.054GluPro: 3.054 ± 0.0
2.036GluGln: 2.036 ± 0.0
1.357GluArg: 1.357 ± 0.0
4.751GluSer: 4.751 ± 0.0
3.393GluThr: 3.393 ± 0.0
6.787GluVal: 6.787 ± 0.0
0.679GluTrp: 0.679 ± 0.0
1.018GluTyr: 1.018 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
3.054PheAla: 3.054 ± 0.0
0.339PheCys: 0.339 ± 0.0
2.375PheAsp: 2.375 ± 0.0
1.357PheGlu: 1.357 ± 0.0
1.018PhePhe: 1.018 ± 0.0
2.036PheGly: 2.036 ± 0.0
0.339PheHis: 0.339 ± 0.0
2.715PheIle: 2.715 ± 0.0
6.447PheLys: 6.447 ± 0.0
2.375PheLeu: 2.375 ± 0.0
1.697PheMet: 1.697 ± 0.0
3.054PheAsn: 3.054 ± 0.0
3.054PhePro: 3.054 ± 0.0
2.036PheGln: 2.036 ± 0.0
1.018PheArg: 1.018 ± 0.0
2.715PheSer: 2.715 ± 0.0
3.733PheThr: 3.733 ± 0.0
2.715PheVal: 2.715 ± 0.0
0.679PheTrp: 0.679 ± 0.0
0.679PheTyr: 0.679 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
1.697GlyAla: 1.697 ± 0.0
1.018GlyCys: 1.018 ± 0.0
3.733GlyAsp: 3.733 ± 0.0
3.733GlyGlu: 3.733 ± 0.0
3.054GlyPhe: 3.054 ± 0.0
1.697GlyGly: 1.697 ± 0.0
1.697GlyHis: 1.697 ± 0.0
4.072GlyIle: 4.072 ± 0.0
2.715GlyLys: 2.715 ± 0.0
6.447GlyLeu: 6.447 ± 0.0
1.697GlyMet: 1.697 ± 0.0
1.697GlyAsn: 1.697 ± 0.0
2.715GlyPro: 2.715 ± 0.0
1.018GlyGln: 1.018 ± 0.0
1.697GlyArg: 1.697 ± 0.0
3.054GlySer: 3.054 ± 0.0
3.054GlyThr: 3.054 ± 0.0
5.429GlyVal: 5.429 ± 0.0
0.0GlyTrp: 0.0 ± 0.0
2.375GlyTyr: 2.375 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
2.036HisAla: 2.036 ± 0.0
1.018HisCys: 1.018 ± 0.0
0.679HisAsp: 0.679 ± 0.0
1.018HisGlu: 1.018 ± 0.0
2.375HisPhe: 2.375 ± 0.0
1.018HisGly: 1.018 ± 0.0
0.0HisHis: 0.0 ± 0.0
1.697HisIle: 1.697 ± 0.0
1.357HisLys: 1.357 ± 0.0
2.036HisLeu: 2.036 ± 0.0
0.0HisMet: 0.0 ± 0.0
0.679HisAsn: 0.679 ± 0.0
1.018HisPro: 1.018 ± 0.0
1.018HisGln: 1.018 ± 0.0
1.697HisArg: 1.697 ± 0.0
0.679HisSer: 0.679 ± 0.0
1.697HisThr: 1.697 ± 0.0
1.018HisVal: 1.018 ± 0.0
0.339HisTrp: 0.339 ± 0.0
1.697HisTyr: 1.697 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.733IleAla: 3.733 ± 0.0
2.715IleCys: 2.715 ± 0.0
4.072IleAsp: 4.072 ± 0.0
3.733IleGlu: 3.733 ± 0.0
2.375IlePhe: 2.375 ± 0.0
2.375IleGly: 2.375 ± 0.0
2.375IleHis: 2.375 ± 0.0
4.411IleIle: 4.411 ± 0.0
5.769IleLys: 5.769 ± 0.0
7.805IleLeu: 7.805 ± 0.0
2.715IleMet: 2.715 ± 0.0
4.072IleAsn: 4.072 ± 0.0
3.393IlePro: 3.393 ± 0.0
3.054IleGln: 3.054 ± 0.0
3.393IleArg: 3.393 ± 0.0
2.715IleSer: 2.715 ± 0.0
4.072IleThr: 4.072 ± 0.0
4.751IleVal: 4.751 ± 0.0
0.339IleTrp: 0.339 ± 0.0
2.375IleTyr: 2.375 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
1.697LysAla: 1.697 ± 0.0
1.018LysCys: 1.018 ± 0.0
5.429LysAsp: 5.429 ± 0.0
4.751LysGlu: 4.751 ± 0.0
2.715LysPhe: 2.715 ± 0.0
3.054LysGly: 3.054 ± 0.0
2.715LysHis: 2.715 ± 0.0
5.429LysIle: 5.429 ± 0.0
5.429LysLys: 5.429 ± 0.0
7.465LysLeu: 7.465 ± 0.0
1.697LysMet: 1.697 ± 0.0
4.072LysAsn: 4.072 ± 0.0
3.054LysPro: 3.054 ± 0.0
2.715LysGln: 2.715 ± 0.0
3.393LysArg: 3.393 ± 0.0
5.09LysSer: 5.09 ± 0.0
4.072LysThr: 4.072 ± 0.0
4.411LysVal: 4.411 ± 0.0
0.679LysTrp: 0.679 ± 0.0
3.733LysTyr: 3.733 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
5.09LeuAla: 5.09 ± 0.0
1.357LeuCys: 1.357 ± 0.0
3.054LeuAsp: 3.054 ± 0.0
5.429LeuGlu: 5.429 ± 0.0
3.393LeuPhe: 3.393 ± 0.0
3.733LeuGly: 3.733 ± 0.0
1.357LeuHis: 1.357 ± 0.0
6.787LeuIle: 6.787 ± 0.0
6.108LeuLys: 6.108 ± 0.0
8.144LeuLeu: 8.144 ± 0.0
2.715LeuMet: 2.715 ± 0.0
8.823LeuAsn: 8.823 ± 0.0
7.465LeuPro: 7.465 ± 0.0
2.375LeuGln: 2.375 ± 0.0
2.375LeuArg: 2.375 ± 0.0
5.09LeuSer: 5.09 ± 0.0
6.787LeuThr: 6.787 ± 0.0
7.805LeuVal: 7.805 ± 0.0
1.018LeuTrp: 1.018 ± 0.0
2.715LeuTyr: 2.715 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
4.072MetAla: 4.072 ± 0.0
0.0MetCys: 0.0 ± 0.0
3.054MetAsp: 3.054 ± 0.0
3.393MetGlu: 3.393 ± 0.0
1.018MetPhe: 1.018 ± 0.0
1.697MetGly: 1.697 ± 0.0
1.018MetHis: 1.018 ± 0.0
1.018MetIle: 1.018 ± 0.0
0.679MetLys: 0.679 ± 0.0
2.375MetLeu: 2.375 ± 0.0
0.679MetMet: 0.679 ± 0.0
1.697MetAsn: 1.697 ± 0.0
1.018MetPro: 1.018 ± 0.0
0.339MetGln: 0.339 ± 0.0
1.697MetArg: 1.697 ± 0.0
1.697MetSer: 1.697 ± 0.0
0.339MetThr: 0.339 ± 0.0
0.679MetVal: 0.679 ± 0.0
1.357MetTrp: 1.357 ± 0.0
0.339MetTyr: 0.339 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
4.411AsnAla: 4.411 ± 0.0
1.697AsnCys: 1.697 ± 0.0
2.375AsnAsp: 2.375 ± 0.0
2.036AsnGlu: 2.036 ± 0.0
4.411AsnPhe: 4.411 ± 0.0
4.411AsnGly: 4.411 ± 0.0
1.357AsnHis: 1.357 ± 0.0
5.769AsnIle: 5.769 ± 0.0
4.072AsnLys: 4.072 ± 0.0
3.054AsnLeu: 3.054 ± 0.0
1.018AsnMet: 1.018 ± 0.0
4.411AsnAsn: 4.411 ± 0.0
4.411AsnPro: 4.411 ± 0.0
2.375AsnGln: 2.375 ± 0.0
2.715AsnArg: 2.715 ± 0.0
2.036AsnSer: 2.036 ± 0.0
2.375AsnThr: 2.375 ± 0.0
2.375AsnVal: 2.375 ± 0.0
0.679AsnTrp: 0.679 ± 0.0
3.393AsnTyr: 3.393 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
1.357ProAla: 1.357 ± 0.0
1.018ProCys: 1.018 ± 0.0
2.715ProAsp: 2.715 ± 0.0
2.715ProGlu: 2.715 ± 0.0
3.054ProPhe: 3.054 ± 0.0
2.375ProGly: 2.375 ± 0.0
1.697ProHis: 1.697 ± 0.0
4.751ProIle: 4.751 ± 0.0
4.072ProLys: 4.072 ± 0.0
6.108ProLeu: 6.108 ± 0.0
0.679ProMet: 0.679 ± 0.0
3.054ProAsn: 3.054 ± 0.0
1.357ProPro: 1.357 ± 0.0
0.679ProGln: 0.679 ± 0.0
0.679ProArg: 0.679 ± 0.0
5.09ProSer: 5.09 ± 0.0
3.054ProThr: 3.054 ± 0.0
2.375ProVal: 2.375 ± 0.0
1.018ProTrp: 1.018 ± 0.0
1.697ProTyr: 1.697 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
2.036GlnAla: 2.036 ± 0.0
0.0GlnCys: 0.0 ± 0.0
1.018GlnAsp: 1.018 ± 0.0
0.339GlnGlu: 0.339 ± 0.0
0.679GlnPhe: 0.679 ± 0.0
2.715GlnGly: 2.715 ± 0.0
1.697GlnHis: 1.697 ± 0.0
3.393GlnIle: 3.393 ± 0.0
1.018GlnLys: 1.018 ± 0.0
3.054GlnLeu: 3.054 ± 0.0
1.697GlnMet: 1.697 ± 0.0
2.375GlnAsn: 2.375 ± 0.0
1.357GlnPro: 1.357 ± 0.0
1.357GlnGln: 1.357 ± 0.0
1.357GlnArg: 1.357 ± 0.0
2.375GlnSer: 2.375 ± 0.0
1.018GlnThr: 1.018 ± 0.0
2.375GlnVal: 2.375 ± 0.0
0.679GlnTrp: 0.679 ± 0.0
1.357GlnTyr: 1.357 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.036ArgAla: 2.036 ± 0.0
0.679ArgCys: 0.679 ± 0.0
3.733ArgAsp: 3.733 ± 0.0
1.697ArgGlu: 1.697 ± 0.0
1.357ArgPhe: 1.357 ± 0.0
1.697ArgGly: 1.697 ± 0.0
1.018ArgHis: 1.018 ± 0.0
2.036ArgIle: 2.036 ± 0.0
3.733ArgLys: 3.733 ± 0.0
5.09ArgLeu: 5.09 ± 0.0
0.679ArgMet: 0.679 ± 0.0
4.411ArgAsn: 4.411 ± 0.0
1.697ArgPro: 1.697 ± 0.0
1.697ArgGln: 1.697 ± 0.0
2.715ArgArg: 2.715 ± 0.0
1.697ArgSer: 1.697 ± 0.0
1.018ArgThr: 1.018 ± 0.0
2.036ArgVal: 2.036 ± 0.0
1.018ArgTrp: 1.018 ± 0.0
0.679ArgTyr: 0.679 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
4.411SerAla: 4.411 ± 0.0
1.357SerCys: 1.357 ± 0.0
3.054SerAsp: 3.054 ± 0.0
3.393SerGlu: 3.393 ± 0.0
3.393SerPhe: 3.393 ± 0.0
5.09SerGly: 5.09 ± 0.0
2.036SerHis: 2.036 ± 0.0
7.805SerIle: 7.805 ± 0.0
3.393SerLys: 3.393 ± 0.0
3.733SerLeu: 3.733 ± 0.0
2.036SerMet: 2.036 ± 0.0
3.393SerAsn: 3.393 ± 0.0
1.018SerPro: 1.018 ± 0.0
1.697SerGln: 1.697 ± 0.0
2.036SerArg: 2.036 ± 0.0
3.733SerSer: 3.733 ± 0.0
5.769SerThr: 5.769 ± 0.0
2.036SerVal: 2.036 ± 0.0
0.339SerTrp: 0.339 ± 0.0
3.393SerTyr: 3.393 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
3.733ThrAla: 3.733 ± 0.0
0.679ThrCys: 0.679 ± 0.0
5.429ThrAsp: 5.429 ± 0.0
5.769ThrGlu: 5.769 ± 0.0
3.054ThrPhe: 3.054 ± 0.0
2.036ThrGly: 2.036 ± 0.0
0.679ThrHis: 0.679 ± 0.0
6.447ThrIle: 6.447 ± 0.0
4.411ThrLys: 4.411 ± 0.0
6.787ThrLeu: 6.787 ± 0.0
2.375ThrMet: 2.375 ± 0.0
4.072ThrAsn: 4.072 ± 0.0
4.072ThrPro: 4.072 ± 0.0
2.715ThrGln: 2.715 ± 0.0
3.054ThrArg: 3.054 ± 0.0
3.393ThrSer: 3.393 ± 0.0
9.501ThrThr: 9.501 ± 0.0
3.054ThrVal: 3.054 ± 0.0
0.339ThrTrp: 0.339 ± 0.0
2.715ThrTyr: 2.715 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
4.411ValAla: 4.411 ± 0.0
0.339ValCys: 0.339 ± 0.0
3.054ValAsp: 3.054 ± 0.0
4.411ValGlu: 4.411 ± 0.0
2.036ValPhe: 2.036 ± 0.0
4.751ValGly: 4.751 ± 0.0
0.679ValHis: 0.679 ± 0.0
2.036ValIle: 2.036 ± 0.0
4.751ValLys: 4.751 ± 0.0
3.733ValLeu: 3.733 ± 0.0
0.679ValMet: 0.679 ± 0.0
2.715ValAsn: 2.715 ± 0.0
4.751ValPro: 4.751 ± 0.0
2.036ValGln: 2.036 ± 0.0
3.054ValArg: 3.054 ± 0.0
6.108ValSer: 6.108 ± 0.0
5.429ValThr: 5.429 ± 0.0
4.072ValVal: 4.072 ± 0.0
0.0ValTrp: 0.0 ± 0.0
2.715ValTyr: 2.715 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.339TrpAla: 0.339 ± 0.0
0.339TrpCys: 0.339 ± 0.0
1.697TrpAsp: 1.697 ± 0.0
0.679TrpGlu: 0.679 ± 0.0
0.339TrpPhe: 0.339 ± 0.0
1.018TrpGly: 1.018 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.339TrpIle: 0.339 ± 0.0
1.018TrpLys: 1.018 ± 0.0
1.697TrpLeu: 1.697 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.339TrpAsn: 0.339 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.339TrpSer: 0.339 ± 0.0
2.375TrpThr: 2.375 ± 0.0
0.339TrpVal: 0.339 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.697TyrAla: 1.697 ± 0.0
0.0TyrCys: 0.0 ± 0.0
1.697TyrAsp: 1.697 ± 0.0
2.375TyrGlu: 2.375 ± 0.0
2.036TyrPhe: 2.036 ± 0.0
2.375TyrGly: 2.375 ± 0.0
0.679TyrHis: 0.679 ± 0.0
2.036TyrIle: 2.036 ± 0.0
3.054TyrLys: 3.054 ± 0.0
3.733TyrLeu: 3.733 ± 0.0
1.697TyrMet: 1.697 ± 0.0
2.375TyrAsn: 2.375 ± 0.0
1.018TyrPro: 1.018 ± 0.0
2.036TyrGln: 2.036 ± 0.0
3.054TyrArg: 3.054 ± 0.0
3.733TyrSer: 3.733 ± 0.0
3.733TyrThr: 3.733 ± 0.0
1.018TyrVal: 1.018 ± 0.0
0.339TyrTrp: 0.339 ± 0.0
1.018TyrTyr: 1.018 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (2948 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski