Amino acid dipepetide frequency for Human feces smacovirus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.096AlaAla: 3.096 ± 1.919
3.096AlaCys: 3.096 ± 1.919
1.548AlaAsp: 1.548 ± 0.96
7.74AlaGlu: 7.74 ± 4.137
0.0AlaPhe: 0.0 ± 0.0
10.836AlaGly: 10.836 ± 4.483
1.548AlaHis: 1.548 ± 0.96
6.192AlaIle: 6.192 ± 0.629
3.096AlaLys: 3.096 ± 0.315
7.74AlaLeu: 7.74 ± 0.33
4.644AlaMet: 4.644 ± 2.879
0.0AlaAsn: 0.0 ± 0.0
1.548AlaPro: 1.548 ± 0.96
1.548AlaGln: 1.548 ± 1.274
1.548AlaArg: 1.548 ± 1.274
9.288AlaSer: 9.288 ± 1.29
4.644AlaThr: 4.644 ± 3.823
3.096AlaVal: 3.096 ± 0.315
0.0AlaTrp: 0.0 ± 0.0
3.096AlaTyr: 3.096 ± 2.548
0.0AlaXaa: 0.0 ± 0.0
Cys
1.548CysAla: 1.548 ± 0.96
0.0CysCys: 0.0 ± 0.0
1.548CysAsp: 1.548 ± 0.96
0.0CysGlu: 0.0 ± 0.0
1.548CysPhe: 1.548 ± 0.96
1.548CysGly: 1.548 ± 0.96
0.0CysHis: 0.0 ± 0.0
1.548CysIle: 1.548 ± 1.274
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.548CysArg: 1.548 ± 1.274
1.548CysSer: 1.548 ± 1.274
0.0CysThr: 0.0 ± 0.0
3.096CysVal: 3.096 ± 1.919
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.548AspAla: 1.548 ± 0.96
1.548AspCys: 1.548 ± 0.96
1.548AspAsp: 1.548 ± 0.96
0.0AspGlu: 0.0 ± 0.0
0.0AspPhe: 0.0 ± 0.0
7.74AspGly: 7.74 ± 0.33
0.0AspHis: 0.0 ± 0.0
7.74AspIle: 7.74 ± 1.904
1.548AspLys: 1.548 ± 1.274
4.644AspLeu: 4.644 ± 0.645
3.096AspMet: 3.096 ± 0.315
3.096AspAsn: 3.096 ± 0.315
4.644AspPro: 4.644 ± 1.589
3.096AspGln: 3.096 ± 1.919
4.644AspArg: 4.644 ± 3.823
4.644AspSer: 4.644 ± 2.879
6.192AspThr: 6.192 ± 0.629
3.096AspVal: 3.096 ± 1.919
1.548AspTrp: 1.548 ± 0.96
1.548AspTyr: 1.548 ± 0.96
0.0AspXaa: 0.0 ± 0.0
Glu
3.096GluAla: 3.096 ± 0.315
1.548GluCys: 1.548 ± 1.274
0.0GluAsp: 0.0 ± 0.0
1.548GluGlu: 1.548 ± 1.274
1.548GluPhe: 1.548 ± 0.96
4.644GluGly: 4.644 ± 3.823
0.0GluHis: 0.0 ± 0.0
3.096GluIle: 3.096 ± 0.315
1.548GluLys: 1.548 ± 1.274
4.644GluLeu: 4.644 ± 0.645
0.0GluMet: 0.0 ± 0.0
0.0GluAsn: 0.0 ± 0.0
0.0GluPro: 0.0 ± 0.0
6.192GluGln: 6.192 ± 2.863
1.548GluArg: 1.548 ± 1.274
4.644GluSer: 4.644 ± 0.645
3.096GluThr: 3.096 ± 1.919
4.644GluVal: 4.644 ± 1.589
1.548GluTrp: 1.548 ± 1.274
1.548GluTyr: 1.548 ± 1.274
0.0GluXaa: 0.0 ± 0.0
Phe
3.096PheAla: 3.096 ± 0.315
0.0PheCys: 0.0 ± 0.0
0.0PheAsp: 0.0 ± 0.0
0.0PheGlu: 0.0 ± 0.0
1.548PhePhe: 1.548 ± 0.96
3.096PheGly: 3.096 ± 0.315
0.0PheHis: 0.0 ± 0.0
0.0PheIle: 0.0 ± 0.0
1.548PheLys: 1.548 ± 1.274
1.548PheLeu: 1.548 ± 0.96
0.0PheMet: 0.0 ± 0.0
1.548PheAsn: 1.548 ± 0.96
0.0PhePro: 0.0 ± 0.0
0.0PheGln: 0.0 ± 0.0
0.0PheArg: 0.0 ± 0.0
1.548PheSer: 1.548 ± 0.96
0.0PheThr: 0.0 ± 0.0
6.192PheVal: 6.192 ± 3.838
0.0PheTrp: 0.0 ± 0.0
1.548PheTyr: 1.548 ± 0.96
0.0PheXaa: 0.0 ± 0.0
Gly
6.192GlyAla: 6.192 ± 2.863
0.0GlyCys: 0.0 ± 0.0
4.644GlyAsp: 4.644 ± 0.645
0.0GlyGlu: 0.0 ± 0.0
4.644GlyPhe: 4.644 ± 0.645
3.096GlyGly: 3.096 ± 0.315
0.0GlyHis: 0.0 ± 0.0
3.096GlyIle: 3.096 ± 0.315
7.74GlyLys: 7.74 ± 0.33
9.288GlyLeu: 9.288 ± 0.944
1.548GlyMet: 1.548 ± 0.96
3.096GlyAsn: 3.096 ± 0.315
7.74GlyPro: 7.74 ± 0.33
1.548GlyGln: 1.548 ± 0.96
4.644GlyArg: 4.644 ± 0.645
7.74GlySer: 7.74 ± 4.798
1.548GlyThr: 1.548 ± 0.96
6.192GlyVal: 6.192 ± 1.604
1.548GlyTrp: 1.548 ± 0.96
4.644GlyTyr: 4.644 ± 3.823
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
3.096HisLys: 3.096 ± 0.315
1.548HisLeu: 1.548 ± 1.274
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
0.0HisSer: 0.0 ± 0.0
3.096HisThr: 3.096 ± 0.315
0.0HisVal: 0.0 ± 0.0
1.548HisTrp: 1.548 ± 1.274
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.548IleAla: 1.548 ± 0.96
0.0IleCys: 0.0 ± 0.0
4.644IleAsp: 4.644 ± 1.589
4.644IleGlu: 4.644 ± 3.823
0.0IlePhe: 0.0 ± 0.0
6.192IleGly: 6.192 ± 5.097
4.644IleHis: 4.644 ± 1.589
7.74IleIle: 7.74 ± 4.137
3.096IleLys: 3.096 ± 2.548
3.096IleLeu: 3.096 ± 1.919
4.644IleMet: 4.644 ± 3.823
1.548IleAsn: 1.548 ± 1.274
3.096IlePro: 3.096 ± 2.548
3.096IleGln: 3.096 ± 1.919
3.096IleArg: 3.096 ± 2.548
0.0IleSer: 0.0 ± 0.0
3.096IleThr: 3.096 ± 1.919
0.0IleVal: 0.0 ± 0.0
0.0IleTrp: 0.0 ± 0.0
3.096IleTyr: 3.096 ± 0.315
0.0IleXaa: 0.0 ± 0.0
Lys
3.096LysAla: 3.096 ± 1.919
0.0LysCys: 0.0 ± 0.0
3.096LysAsp: 3.096 ± 2.548
3.096LysGlu: 3.096 ± 0.315
0.0LysPhe: 0.0 ± 0.0
1.548LysGly: 1.548 ± 0.96
0.0LysHis: 0.0 ± 0.0
1.548LysIle: 1.548 ± 1.274
3.096LysLys: 3.096 ± 0.315
4.644LysLeu: 4.644 ± 1.589
3.096LysMet: 3.096 ± 1.919
1.548LysAsn: 1.548 ± 0.96
1.548LysPro: 1.548 ± 1.274
3.096LysGln: 3.096 ± 0.315
1.548LysArg: 1.548 ± 1.274
1.548LysSer: 1.548 ± 1.274
6.192LysThr: 6.192 ± 2.863
9.288LysVal: 9.288 ± 1.29
3.096LysTrp: 3.096 ± 2.548
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
9.288LeuAla: 9.288 ± 0.944
0.0LeuCys: 0.0 ± 0.0
3.096LeuAsp: 3.096 ± 0.315
1.548LeuGlu: 1.548 ± 1.274
0.0LeuPhe: 0.0 ± 0.0
4.644LeuGly: 4.644 ± 2.879
0.0LeuHis: 0.0 ± 0.0
3.096LeuIle: 3.096 ± 0.315
3.096LeuLys: 3.096 ± 0.315
6.192LeuLeu: 6.192 ± 3.838
0.0LeuMet: 0.0 ± 0.0
1.548LeuAsn: 1.548 ± 0.96
6.192LeuPro: 6.192 ± 3.838
4.644LeuGln: 4.644 ± 0.645
6.192LeuArg: 6.192 ± 0.629
9.288LeuSer: 9.288 ± 1.29
4.644LeuThr: 4.644 ± 0.645
3.096LeuVal: 3.096 ± 1.919
0.0LeuTrp: 0.0 ± 0.0
6.192LeuTyr: 6.192 ± 0.629
0.0LeuXaa: 0.0 ± 0.0
Met
3.096MetAla: 3.096 ± 2.548
0.0MetCys: 0.0 ± 0.0
3.096MetAsp: 3.096 ± 2.548
1.548MetGlu: 1.548 ± 0.96
3.096MetPhe: 3.096 ± 1.919
3.096MetGly: 3.096 ± 0.315
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.548MetLys: 1.548 ± 1.274
3.096MetLeu: 3.096 ± 1.919
0.0MetMet: 0.0 ± 0.0
1.548MetAsn: 1.548 ± 1.274
4.644MetPro: 4.644 ± 0.645
0.0MetGln: 0.0 ± 0.0
1.548MetArg: 1.548 ± 0.96
1.548MetSer: 1.548 ± 0.96
6.192MetThr: 6.192 ± 0.629
4.644MetVal: 4.644 ± 0.645
1.548MetTrp: 1.548 ± 0.96
1.548MetTyr: 1.548 ± 0.96
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
0.0AsnCys: 0.0 ± 0.0
3.096AsnAsp: 3.096 ± 0.315
1.548AsnGlu: 1.548 ± 0.96
0.0AsnPhe: 0.0 ± 0.0
0.0AsnGly: 0.0 ± 0.0
1.548AsnHis: 1.548 ± 1.274
4.644AsnIle: 4.644 ± 3.823
0.0AsnLys: 0.0 ± 0.0
3.096AsnLeu: 3.096 ± 1.919
1.548AsnMet: 1.548 ± 0.96
1.548AsnAsn: 1.548 ± 1.274
4.644AsnPro: 4.644 ± 0.645
0.0AsnGln: 0.0 ± 0.0
1.548AsnArg: 1.548 ± 0.96
4.644AsnSer: 4.644 ± 2.879
3.096AsnThr: 3.096 ± 0.315
1.548AsnVal: 1.548 ± 0.96
3.096AsnTrp: 3.096 ± 0.315
1.548AsnTyr: 1.548 ± 0.96
0.0AsnXaa: 0.0 ± 0.0
Pro
9.288ProAla: 9.288 ± 1.29
0.0ProCys: 0.0 ± 0.0
4.644ProAsp: 4.644 ± 2.879
1.548ProGlu: 1.548 ± 1.274
0.0ProPhe: 0.0 ± 0.0
3.096ProGly: 3.096 ± 1.919
0.0ProHis: 0.0 ± 0.0
4.644ProIle: 4.644 ± 0.645
1.548ProLys: 1.548 ± 1.274
3.096ProLeu: 3.096 ± 1.919
0.0ProMet: 0.0 ± 0.826
1.548ProAsn: 1.548 ± 0.96
3.096ProPro: 3.096 ± 0.315
4.644ProGln: 4.644 ± 0.645
6.192ProArg: 6.192 ± 2.863
4.644ProSer: 4.644 ± 1.589
0.0ProThr: 0.0 ± 0.0
0.0ProVal: 0.0 ± 0.0
0.0ProTrp: 0.0 ± 0.0
3.096ProTyr: 3.096 ± 0.315
0.0ProXaa: 0.0 ± 0.0
Gln
7.74GlnAla: 7.74 ± 2.564
1.548GlnCys: 1.548 ± 1.274
1.548GlnAsp: 1.548 ± 0.96
1.548GlnGlu: 1.548 ± 1.274
1.548GlnPhe: 1.548 ± 0.96
6.192GlnGly: 6.192 ± 0.629
1.548GlnHis: 1.548 ± 1.274
0.0GlnIle: 0.0 ± 0.0
3.096GlnLys: 3.096 ± 0.315
3.096GlnLeu: 3.096 ± 0.315
1.548GlnMet: 1.548 ± 1.274
1.548GlnAsn: 1.548 ± 0.96
3.096GlnPro: 3.096 ± 0.315
1.548GlnGln: 1.548 ± 1.274
0.0GlnArg: 0.0 ± 0.0
1.548GlnSer: 1.548 ± 0.96
1.548GlnThr: 1.548 ± 0.96
3.096GlnVal: 3.096 ± 0.315
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
1.548ArgAla: 1.548 ± 1.274
0.0ArgCys: 0.0 ± 0.0
3.096ArgAsp: 3.096 ± 2.548
4.644ArgGlu: 4.644 ± 0.645
6.192ArgPhe: 6.192 ± 0.629
3.096ArgGly: 3.096 ± 0.315
0.0ArgHis: 0.0 ± 0.0
4.644ArgIle: 4.644 ± 1.589
1.548ArgLys: 1.548 ± 0.96
7.74ArgLeu: 7.74 ± 2.564
0.0ArgMet: 0.0 ± 0.0
0.0ArgAsn: 0.0 ± 0.0
4.644ArgPro: 4.644 ± 0.645
1.548ArgGln: 1.548 ± 1.274
0.0ArgArg: 0.0 ± 0.0
3.096ArgSer: 3.096 ± 2.548
3.096ArgThr: 3.096 ± 2.548
0.0ArgVal: 0.0 ± 0.0
1.548ArgTrp: 1.548 ± 1.274
1.548ArgTyr: 1.548 ± 1.274
0.0ArgXaa: 0.0 ± 0.0
Ser
4.644SerAla: 4.644 ± 0.645
3.096SerCys: 3.096 ± 1.919
10.836SerAsp: 10.836 ± 2.249
6.192SerGlu: 6.192 ± 1.604
1.548SerPhe: 1.548 ± 0.96
6.192SerGly: 6.192 ± 1.604
0.0SerHis: 0.0 ± 0.0
3.096SerIle: 3.096 ± 2.548
1.548SerLys: 1.548 ± 0.96
3.096SerLeu: 3.096 ± 0.315
6.192SerMet: 6.192 ± 3.386
4.644SerAsn: 4.644 ± 2.879
1.548SerPro: 1.548 ± 1.274
1.548SerGln: 1.548 ± 0.96
3.096SerArg: 3.096 ± 1.919
7.74SerSer: 7.74 ± 2.564
7.74SerThr: 7.74 ± 2.564
3.096SerVal: 3.096 ± 1.919
6.192SerTrp: 6.192 ± 5.097
1.548SerTyr: 1.548 ± 0.96
0.0SerXaa: 0.0 ± 0.0
Thr
6.192ThrAla: 6.192 ± 2.863
0.0ThrCys: 0.0 ± 0.0
3.096ThrAsp: 3.096 ± 1.919
1.548ThrGlu: 1.548 ± 1.274
0.0ThrPhe: 0.0 ± 0.0
1.548ThrGly: 1.548 ± 1.274
0.0ThrHis: 0.0 ± 0.0
1.548ThrIle: 1.548 ± 1.274
1.548ThrLys: 1.548 ± 0.96
1.548ThrLeu: 1.548 ± 0.96
6.192ThrMet: 6.192 ± 2.863
9.288ThrAsn: 9.288 ± 3.178
1.548ThrPro: 1.548 ± 0.96
3.096ThrGln: 3.096 ± 1.919
6.192ThrArg: 6.192 ± 0.629
9.288ThrSer: 9.288 ± 5.757
0.0ThrThr: 0.0 ± 0.0
7.74ThrVal: 7.74 ± 1.904
3.096ThrTrp: 3.096 ± 1.919
3.096ThrTyr: 3.096 ± 1.919
0.0ThrXaa: 0.0 ± 0.0
Val
7.74ValAla: 7.74 ± 0.33
1.548ValCys: 1.548 ± 0.96
4.644ValAsp: 4.644 ± 2.879
3.096ValGlu: 3.096 ± 1.919
0.0ValPhe: 0.0 ± 0.0
7.74ValGly: 7.74 ± 0.33
0.0ValHis: 0.0 ± 0.0
3.096ValIle: 3.096 ± 2.548
6.192ValLys: 6.192 ± 2.863
1.548ValLeu: 1.548 ± 0.96
7.74ValMet: 7.74 ± 0.33
3.096ValAsn: 3.096 ± 1.919
1.548ValPro: 1.548 ± 0.96
0.0ValGln: 0.0 ± 0.0
1.548ValArg: 1.548 ± 1.274
4.644ValSer: 4.644 ± 2.879
7.74ValThr: 7.74 ± 4.798
7.74ValVal: 7.74 ± 0.33
1.548ValTrp: 1.548 ± 1.274
3.096ValTyr: 3.096 ± 1.919
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
3.096TrpAsp: 3.096 ± 2.548
1.548TrpGlu: 1.548 ± 1.274
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.548TrpIle: 1.548 ± 1.274
4.644TrpLys: 4.644 ± 0.645
1.548TrpLeu: 1.548 ± 1.274
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
3.096TrpGln: 3.096 ± 2.548
0.0TrpArg: 0.0 ± 0.0
3.096TrpSer: 3.096 ± 0.315
1.548TrpThr: 1.548 ± 0.96
3.096TrpVal: 3.096 ± 0.315
0.0TrpTrp: 0.0 ± 0.0
3.096TrpTyr: 3.096 ± 0.315
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.548TyrAla: 1.548 ± 0.96
1.548TyrCys: 1.548 ± 1.274
4.644TyrAsp: 4.644 ± 0.645
3.096TyrGlu: 3.096 ± 2.548
0.0TyrPhe: 0.0 ± 0.0
4.644TyrGly: 4.644 ± 2.879
0.0TyrHis: 0.0 ± 0.0
0.0TyrIle: 0.0 ± 0.0
1.548TyrLys: 1.548 ± 0.96
1.548TyrLeu: 1.548 ± 1.274
0.0TyrMet: 0.0 ± 0.0
1.548TyrAsn: 1.548 ± 0.96
3.096TyrPro: 3.096 ± 0.315
3.096TyrGln: 3.096 ± 0.315
3.096TyrArg: 3.096 ± 1.919
3.096TyrSer: 3.096 ± 2.548
3.096TyrThr: 3.096 ± 2.548
4.644TyrVal: 4.644 ± 0.645
0.0TyrTrp: 0.0 ± 0.0
3.096TyrTyr: 3.096 ± 1.919
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (647 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski