Amino acid dipepetide frequency for Beihai picorna-like virus 63

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.589AlaAla: 3.589 ± 2.035
0.0AlaCys: 0.0 ± 0.0
1.994AlaAsp: 1.994 ± 0.628
3.987AlaGlu: 3.987 ± 0.126
3.589AlaPhe: 3.589 ± 0.339
1.595AlaGly: 1.595 ± 0.842
1.196AlaHis: 1.196 ± 0.49
2.791AlaIle: 2.791 ± 0.364
2.791AlaLys: 2.791 ± 0.201
5.981AlaLeu: 5.981 ± 1.884
1.196AlaMet: 1.196 ± 0.641
0.797AlaAsn: 0.797 ± 0.427
1.595AlaPro: 1.595 ± 0.276
1.595AlaGln: 1.595 ± 0.289
1.994AlaArg: 1.994 ± 0.628
3.987AlaSer: 3.987 ± 1.256
3.987AlaThr: 3.987 ± 2.387
3.19AlaVal: 3.19 ± 0.013
0.399AlaTrp: 0.399 ± 0.352
0.399AlaTyr: 0.399 ± 0.352
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.797CysAsp: 0.797 ± 0.427
0.399CysGlu: 0.399 ± 0.214
0.399CysPhe: 0.399 ± 0.214
0.399CysGly: 0.399 ± 0.214
0.0CysHis: 0.0 ± 0.0
1.595CysIle: 1.595 ± 0.842
0.797CysLys: 0.797 ± 0.138
0.797CysLeu: 0.797 ± 0.427
0.399CysMet: 0.399 ± 0.214
1.196CysAsn: 1.196 ± 0.075
0.797CysPro: 0.797 ± 0.138
0.399CysGln: 0.399 ± 0.214
0.797CysArg: 0.797 ± 0.138
0.797CysSer: 0.797 ± 0.427
1.196CysThr: 1.196 ± 0.075
0.399CysVal: 0.399 ± 0.214
0.0CysTrp: 0.0 ± 0.0
0.399CysTyr: 0.399 ± 0.214
0.0CysXaa: 0.0 ± 0.0
Asp
1.196AspAla: 1.196 ± 0.49
2.392AspCys: 2.392 ± 0.151
3.589AspAsp: 3.589 ± 0.339
4.785AspGlu: 4.785 ± 1.432
4.785AspPhe: 4.785 ± 0.302
2.791AspGly: 2.791 ± 0.364
0.399AspHis: 0.399 ± 0.214
5.981AspIle: 5.981 ± 0.754
5.183AspLys: 5.183 ± 1.08
6.778AspLeu: 6.778 ± 0.326
2.392AspMet: 2.392 ± 0.98
4.386AspAsn: 4.386 ± 1.043
3.589AspPro: 3.589 ± 0.904
0.797AspGln: 0.797 ± 0.703
1.196AspArg: 1.196 ± 0.075
3.589AspSer: 3.589 ± 0.226
2.392AspThr: 2.392 ± 0.151
4.785AspVal: 4.785 ± 0.264
0.0AspTrp: 0.0 ± 0.0
2.392AspTyr: 2.392 ± 0.716
0.0AspXaa: 0.0 ± 0.0
Glu
3.987GluAla: 3.987 ± 0.691
0.797GluCys: 0.797 ± 0.427
4.785GluAsp: 4.785 ± 0.867
2.791GluGlu: 2.791 ± 0.201
2.392GluPhe: 2.392 ± 0.151
3.987GluGly: 3.987 ± 0.44
1.196GluHis: 1.196 ± 0.641
3.589GluIle: 3.589 ± 1.357
3.589GluLys: 3.589 ± 0.226
6.778GluLeu: 6.778 ± 0.326
1.595GluMet: 1.595 ± 0.289
2.392GluAsn: 2.392 ± 0.716
1.196GluPro: 1.196 ± 0.49
1.196GluGln: 1.196 ± 0.49
0.797GluArg: 0.797 ± 0.703
7.974GluSer: 7.974 ± 0.816
2.392GluThr: 2.392 ± 0.716
2.392GluVal: 2.392 ± 0.151
0.399GluTrp: 0.399 ± 0.352
3.987GluTyr: 3.987 ± 1.57
0.0GluXaa: 0.0 ± 0.0
Phe
3.589PheAla: 3.589 ± 0.339
0.0PheCys: 0.0 ± 0.0
3.19PheAsp: 3.19 ± 0.013
1.595PheGlu: 1.595 ± 0.276
4.785PhePhe: 4.785 ± 0.302
3.987PheGly: 3.987 ± 0.126
1.595PheHis: 1.595 ± 0.276
5.183PheIle: 5.183 ± 0.05
4.386PheLys: 4.386 ± 0.653
3.987PheLeu: 3.987 ± 1.57
0.399PheMet: 0.399 ± 0.214
2.791PheAsn: 2.791 ± 0.201
1.595PhePro: 1.595 ± 0.854
1.196PheGln: 1.196 ± 0.075
3.19PheArg: 3.19 ± 0.553
5.582PheSer: 5.582 ± 0.163
4.386PheThr: 4.386 ± 0.477
6.778PheVal: 6.778 ± 0.892
0.0PheTrp: 0.0 ± 0.0
3.19PheTyr: 3.19 ± 0.578
0.0PheXaa: 0.0 ± 0.0
Gly
3.19GlyAla: 3.19 ± 1.118
0.399GlyCys: 0.399 ± 0.214
4.785GlyAsp: 4.785 ± 1.432
2.392GlyGlu: 2.392 ± 0.415
1.994GlyPhe: 1.994 ± 0.628
3.589GlyGly: 3.589 ± 0.339
0.399GlyHis: 0.399 ± 0.214
3.589GlyIle: 3.589 ± 0.791
4.785GlyLys: 4.785 ± 0.867
3.987GlyLeu: 3.987 ± 1.57
0.399GlyMet: 0.399 ± 0.214
3.589GlyAsn: 3.589 ± 0.339
1.994GlyPro: 1.994 ± 0.628
0.797GlyGln: 0.797 ± 0.138
0.797GlyArg: 0.797 ± 0.138
3.589GlySer: 3.589 ± 0.339
3.589GlyThr: 3.589 ± 2.035
1.994GlyVal: 1.994 ± 0.063
0.0GlyTrp: 0.0 ± 0.0
1.994GlyTyr: 1.994 ± 0.503
0.0GlyXaa: 0.0 ± 0.0
His
0.399HisAla: 0.399 ± 0.352
0.399HisCys: 0.399 ± 0.214
1.994HisAsp: 1.994 ± 1.068
0.399HisGlu: 0.399 ± 0.214
1.196HisPhe: 1.196 ± 0.075
1.595HisGly: 1.595 ± 0.289
0.399HisHis: 0.399 ± 0.214
0.797HisIle: 0.797 ± 0.427
2.392HisLys: 2.392 ± 0.151
0.797HisLeu: 0.797 ± 0.427
0.0HisMet: 0.0 ± 0.0
0.797HisAsn: 0.797 ± 0.427
0.399HisPro: 0.399 ± 0.352
0.399HisGln: 0.399 ± 0.214
0.797HisArg: 0.797 ± 0.703
1.196HisSer: 1.196 ± 0.075
3.19HisThr: 3.19 ± 1.143
0.399HisVal: 0.399 ± 0.214
0.399HisTrp: 0.399 ± 0.352
0.797HisTyr: 0.797 ± 0.138
0.0HisXaa: 0.0 ± 0.0
Ile
3.987IleAla: 3.987 ± 0.126
0.797IleCys: 0.797 ± 0.427
3.987IleAsp: 3.987 ± 0.44
5.183IleGlu: 5.183 ± 0.515
3.987IlePhe: 3.987 ± 0.126
3.987IleGly: 3.987 ± 0.126
1.196IleHis: 1.196 ± 0.641
4.785IleIle: 4.785 ± 1.432
3.987IleLys: 3.987 ± 1.005
4.386IleLeu: 4.386 ± 1.784
1.196IleMet: 1.196 ± 0.641
7.177IleAsn: 7.177 ± 0.678
2.392IlePro: 2.392 ± 0.98
1.196IleGln: 1.196 ± 0.49
2.791IleArg: 2.791 ± 0.766
7.177IleSer: 7.177 ± 0.452
2.791IleThr: 2.791 ± 0.364
6.38IleVal: 6.38 ± 1.156
0.0IleTrp: 0.0 ± 0.0
3.987IleTyr: 3.987 ± 0.44
0.0IleXaa: 0.0 ± 0.0
Lys
3.19LysAla: 3.19 ± 0.553
1.196LysCys: 1.196 ± 0.075
5.183LysAsp: 5.183 ± 1.08
4.386LysGlu: 4.386 ± 0.088
5.183LysPhe: 5.183 ± 0.05
2.791LysGly: 2.791 ± 0.93
2.791LysHis: 2.791 ± 1.495
5.981LysIle: 5.981 ± 0.188
6.38LysLys: 6.38 ± 1.156
6.778LysLeu: 6.778 ± 0.804
2.392LysMet: 2.392 ± 1.281
3.589LysAsn: 3.589 ± 0.791
1.994LysPro: 1.994 ± 0.063
1.994LysGln: 1.994 ± 0.063
3.987LysArg: 3.987 ± 0.126
7.576LysSer: 7.576 ± 2.927
3.589LysThr: 3.589 ± 0.791
3.589LysVal: 3.589 ± 0.791
0.399LysTrp: 0.399 ± 0.214
3.987LysTyr: 3.987 ± 0.44
0.0LysXaa: 0.0 ± 0.0
Leu
3.19LeuAla: 3.19 ± 0.553
0.797LeuCys: 0.797 ± 0.427
5.582LeuAsp: 5.582 ± 0.402
5.582LeuGlu: 5.582 ± 0.163
7.576LeuPhe: 7.576 ± 0.666
5.582LeuGly: 5.582 ± 0.163
1.196LeuHis: 1.196 ± 0.075
5.981LeuIle: 5.981 ± 1.508
9.569LeuLys: 9.569 ± 1.734
7.576LeuLeu: 7.576 ± 1.231
5.183LeuMet: 5.183 ± 1.08
1.595LeuAsn: 1.595 ± 0.276
3.19LeuPro: 3.19 ± 0.013
1.196LeuGln: 1.196 ± 0.075
2.392LeuArg: 2.392 ± 1.281
10.367LeuSer: 10.367 ± 2.362
5.582LeuThr: 5.582 ± 0.402
4.785LeuVal: 4.785 ± 1.432
1.196LeuTrp: 1.196 ± 0.075
3.589LeuTyr: 3.589 ± 0.226
0.0LeuXaa: 0.0 ± 0.0
Met
1.595MetAla: 1.595 ± 0.842
1.196MetCys: 1.196 ± 0.075
0.797MetAsp: 0.797 ± 0.427
3.987MetGlu: 3.987 ± 0.44
1.196MetPhe: 1.196 ± 0.49
0.0MetGly: 0.0 ± 0.0
0.399MetHis: 0.399 ± 0.214
1.196MetIle: 1.196 ± 0.641
1.196MetLys: 1.196 ± 0.641
1.595MetLeu: 1.595 ± 0.289
0.0MetMet: 0.0 ± 0.0
0.797MetAsn: 0.797 ± 0.138
1.994MetPro: 1.994 ± 0.503
0.399MetGln: 0.399 ± 0.214
1.595MetArg: 1.595 ± 0.289
1.196MetSer: 1.196 ± 0.641
1.994MetThr: 1.994 ± 0.063
0.797MetVal: 0.797 ± 0.138
0.399MetTrp: 0.399 ± 0.352
1.994MetTyr: 1.994 ± 1.068
0.0MetXaa: 0.0 ± 0.0
Asn
1.196AsnAla: 1.196 ± 0.075
0.0AsnCys: 0.0 ± 0.0
2.791AsnAsp: 2.791 ± 0.201
2.392AsnGlu: 2.392 ± 0.415
3.19AsnPhe: 3.19 ± 0.578
2.392AsnGly: 2.392 ± 0.415
1.994AsnHis: 1.994 ± 0.063
6.778AsnIle: 6.778 ± 0.804
5.183AsnLys: 5.183 ± 1.646
3.987AsnLeu: 3.987 ± 1.005
1.196AsnMet: 1.196 ± 0.148
5.582AsnAsn: 5.582 ± 0.967
3.987AsnPro: 3.987 ± 0.691
1.595AsnGln: 1.595 ± 0.276
1.595AsnArg: 1.595 ± 0.289
6.778AsnSer: 6.778 ± 1.457
3.987AsnThr: 3.987 ± 1.821
2.791AsnVal: 2.791 ± 0.766
0.797AsnTrp: 0.797 ± 0.427
2.392AsnTyr: 2.392 ± 0.151
0.0AsnXaa: 0.0 ± 0.0
Pro
1.595ProAla: 1.595 ± 0.276
0.0ProCys: 0.0 ± 0.0
2.791ProAsp: 2.791 ± 0.201
3.589ProGlu: 3.589 ± 1.357
2.392ProPhe: 2.392 ± 0.415
1.196ProGly: 1.196 ± 0.641
0.0ProHis: 0.0 ± 0.0
1.994ProIle: 1.994 ± 1.193
3.987ProLys: 3.987 ± 0.126
4.785ProLeu: 4.785 ± 0.867
1.196ProMet: 1.196 ± 0.49
1.196ProAsn: 1.196 ± 1.055
0.399ProPro: 0.399 ± 0.214
0.0ProGln: 0.0 ± 0.0
1.994ProArg: 1.994 ± 0.628
1.994ProSer: 1.994 ± 0.063
2.791ProThr: 2.791 ± 0.766
3.589ProVal: 3.589 ± 0.904
0.399ProTrp: 0.399 ± 0.352
1.994ProTyr: 1.994 ± 0.063
0.0ProXaa: 0.0 ± 0.0
Gln
1.196GlnAla: 1.196 ± 0.49
0.399GlnCys: 0.399 ± 0.352
0.399GlnAsp: 0.399 ± 0.214
0.797GlnGlu: 0.797 ± 0.138
0.0GlnPhe: 0.0 ± 0.0
0.797GlnGly: 0.797 ± 0.703
0.0GlnHis: 0.0 ± 0.0
2.392GlnIle: 2.392 ± 0.151
0.797GlnLys: 0.797 ± 0.703
2.791GlnLeu: 2.791 ± 0.201
0.0GlnMet: 0.0 ± 0.0
1.196GlnAsn: 1.196 ± 0.641
2.392GlnPro: 2.392 ± 0.415
0.399GlnGln: 0.399 ± 0.352
0.399GlnArg: 0.399 ± 0.214
1.994GlnSer: 1.994 ± 0.063
0.399GlnThr: 0.399 ± 0.352
1.595GlnVal: 1.595 ± 0.854
0.0GlnTrp: 0.0 ± 0.0
2.392GlnTyr: 2.392 ± 0.415
0.0GlnXaa: 0.0 ± 0.0
Arg
1.994ArgAla: 1.994 ± 0.063
0.399ArgCys: 0.399 ± 0.352
1.994ArgAsp: 1.994 ± 0.063
1.994ArgGlu: 1.994 ± 1.068
3.589ArgPhe: 3.589 ± 0.791
2.392ArgGly: 2.392 ± 0.415
0.399ArgHis: 0.399 ± 0.352
1.196ArgIle: 1.196 ± 0.075
3.589ArgLys: 3.589 ± 1.47
3.987ArgLeu: 3.987 ± 1.256
1.196ArgMet: 1.196 ± 0.075
3.19ArgAsn: 3.19 ± 0.578
1.196ArgPro: 1.196 ± 1.055
1.196ArgGln: 1.196 ± 0.641
1.994ArgArg: 1.994 ± 0.503
3.19ArgSer: 3.19 ± 1.118
1.994ArgThr: 1.994 ± 0.063
2.392ArgVal: 2.392 ± 0.415
0.399ArgTrp: 0.399 ± 0.352
0.399ArgTyr: 0.399 ± 0.214
0.0ArgXaa: 0.0 ± 0.0
Ser
2.392SerAla: 2.392 ± 1.545
0.399SerCys: 0.399 ± 0.352
6.778SerAsp: 6.778 ± 4.284
5.183SerGlu: 5.183 ± 0.515
8.772SerPhe: 8.772 ± 0.741
5.183SerGly: 5.183 ± 1.181
1.196SerHis: 1.196 ± 0.075
8.373SerIle: 8.373 ± 0.528
7.576SerLys: 7.576 ± 2.362
8.373SerLeu: 8.373 ± 1.093
2.392SerMet: 2.392 ± 0.559
5.582SerAsn: 5.582 ± 0.967
2.791SerPro: 2.791 ± 0.364
2.791SerGln: 2.791 ± 0.201
3.19SerArg: 3.19 ± 0.578
9.968SerSer: 9.968 ± 0.251
5.582SerThr: 5.582 ± 2.663
6.38SerVal: 6.38 ± 0.025
0.0SerTrp: 0.0 ± 0.0
3.987SerTyr: 3.987 ± 0.691
0.0SerXaa: 0.0 ± 0.0
Thr
3.987ThrAla: 3.987 ± 1.256
0.797ThrCys: 0.797 ± 0.427
3.19ThrAsp: 3.19 ± 1.118
1.196ThrGlu: 1.196 ± 0.49
3.589ThrPhe: 3.589 ± 0.339
1.196ThrGly: 1.196 ± 0.075
0.399ThrHis: 0.399 ± 0.214
3.589ThrIle: 3.589 ± 0.226
0.797ThrLys: 0.797 ± 0.427
8.772ThrLeu: 8.772 ± 0.389
1.196ThrMet: 1.196 ± 0.49
5.582ThrAsn: 5.582 ± 2.663
0.797ThrPro: 0.797 ± 0.427
0.797ThrGln: 0.797 ± 0.138
2.791ThrArg: 2.791 ± 1.332
7.974ThrSer: 7.974 ± 1.947
5.183ThrThr: 5.183 ± 3.442
3.19ThrVal: 3.19 ± 0.553
0.0ThrTrp: 0.0 ± 0.0
3.589ThrTyr: 3.589 ± 0.339
0.0ThrXaa: 0.0 ± 0.0
Val
1.994ValAla: 1.994 ± 0.503
1.196ValCys: 1.196 ± 0.075
4.785ValAsp: 4.785 ± 0.829
3.987ValGlu: 3.987 ± 0.126
0.797ValPhe: 0.797 ± 0.427
2.791ValGly: 2.791 ± 0.364
2.392ValHis: 2.392 ± 0.716
3.19ValIle: 3.19 ± 0.013
6.38ValLys: 6.38 ± 1.156
3.987ValLeu: 3.987 ± 0.691
0.797ValMet: 0.797 ± 0.138
3.589ValAsn: 3.589 ± 0.791
1.994ValPro: 1.994 ± 0.628
1.595ValGln: 1.595 ± 0.276
3.987ValArg: 3.987 ± 0.691
7.177ValSer: 7.177 ± 0.452
2.791ValThr: 2.791 ± 1.332
3.589ValVal: 3.589 ± 0.904
0.0ValTrp: 0.0 ± 0.0
4.386ValTyr: 4.386 ± 0.653
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.399TrpCys: 0.399 ± 0.214
0.797TrpAsp: 0.797 ± 0.703
0.0TrpGlu: 0.0 ± 0.0
0.399TrpPhe: 0.399 ± 0.214
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.399TrpIle: 0.399 ± 0.352
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.797TrpAsn: 0.797 ± 0.138
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.399TrpArg: 0.399 ± 0.352
1.196TrpSer: 1.196 ± 0.49
0.399TrpThr: 0.399 ± 0.214
0.399TrpVal: 0.399 ± 0.214
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.386TyrAla: 4.386 ± 0.088
0.0TyrCys: 0.0 ± 0.0
3.19TyrAsp: 3.19 ± 1.709
3.589TyrGlu: 3.589 ± 0.339
1.595TyrPhe: 1.595 ± 0.842
1.595TyrGly: 1.595 ± 0.289
1.595TyrHis: 1.595 ± 0.276
1.994TyrIle: 1.994 ± 1.068
3.589TyrLys: 3.589 ± 1.357
5.582TyrLeu: 5.582 ± 0.163
0.797TyrMet: 0.797 ± 0.427
4.785TyrAsn: 4.785 ± 1.998
3.589TyrPro: 3.589 ± 0.791
0.797TyrGln: 0.797 ± 0.703
1.994TyrArg: 1.994 ± 0.503
3.987TyrSer: 3.987 ± 0.691
0.399TyrThr: 0.399 ± 0.352
1.994TyrVal: 1.994 ± 0.628
0.399TyrTrp: 0.399 ± 0.214
2.392TyrTyr: 2.392 ± 0.415
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2509 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski