Amino acid dipepetide frequency for Beihai picorna-like virus 9

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.367AlaAla: 5.367 ± 1.162
0.894AlaCys: 0.894 ± 0.476
5.814AlaAsp: 5.814 ± 1.594
5.367AlaGlu: 5.367 ± 1.516
4.025AlaPhe: 4.025 ± 0.802
2.683AlaGly: 2.683 ± 0.581
1.342AlaHis: 1.342 ± 0.044
4.025AlaIle: 4.025 ± 0.537
4.025AlaLys: 4.025 ± 0.802
4.025AlaLeu: 4.025 ± 1.472
2.236AlaMet: 2.236 ± 0.15
2.683AlaAsn: 2.683 ± 0.581
2.236AlaPro: 2.236 ± 0.819
1.789AlaGln: 1.789 ± 0.282
3.578AlaArg: 3.578 ± 0.564
4.919AlaSer: 4.919 ± 2.739
3.578AlaThr: 3.578 ± 0.105
5.814AlaVal: 5.814 ± 0.255
0.447AlaTrp: 0.447 ± 0.432
4.472AlaTyr: 4.472 ± 1.638
0.0AlaXaa: 0.0 ± 0.0
Cys
2.236CysAla: 2.236 ± 0.52
0.447CysCys: 0.447 ± 0.238
0.894CysAsp: 0.894 ± 0.194
0.0CysGlu: 0.0 ± 0.0
0.447CysPhe: 0.447 ± 0.238
3.131CysGly: 3.131 ± 0.996
0.0CysHis: 0.0 ± 0.0
0.447CysIle: 0.447 ± 0.238
0.447CysLys: 0.447 ± 0.238
2.683CysLeu: 2.683 ± 0.581
1.789CysMet: 1.789 ± 0.952
1.342CysAsn: 1.342 ± 0.044
1.789CysPro: 1.789 ± 0.387
0.447CysGln: 0.447 ± 0.238
0.447CysArg: 0.447 ± 0.432
0.894CysSer: 0.894 ± 0.476
2.236CysThr: 2.236 ± 0.52
0.894CysVal: 0.894 ± 0.476
0.894CysTrp: 0.894 ± 0.476
1.342CysTyr: 1.342 ± 0.044
0.0CysXaa: 0.0 ± 0.0
Asp
3.578AspAla: 3.578 ± 0.564
1.342AspCys: 1.342 ± 0.714
3.131AspAsp: 3.131 ± 0.996
5.367AspGlu: 5.367 ± 0.846
3.131AspPhe: 3.131 ± 0.343
1.789AspGly: 1.789 ± 0.282
0.447AspHis: 0.447 ± 0.432
4.472AspIle: 4.472 ± 0.969
6.261AspLys: 6.261 ± 1.322
9.392AspLeu: 9.392 ± 1.648
3.131AspMet: 3.131 ± 0.195
0.894AspAsn: 0.894 ± 0.194
2.683AspPro: 2.683 ± 1.251
0.447AspGln: 0.447 ± 0.432
2.236AspArg: 2.236 ± 0.52
5.367AspSer: 5.367 ± 1.832
3.131AspThr: 3.131 ± 1.013
2.683AspVal: 2.683 ± 0.088
2.236AspTrp: 2.236 ± 0.52
4.025AspTyr: 4.025 ± 0.802
0.0AspXaa: 0.0 ± 0.0
Glu
3.131GluAla: 3.131 ± 1.013
0.894GluCys: 0.894 ± 0.476
4.919GluAsp: 4.919 ± 0.061
1.789GluGlu: 1.789 ± 0.952
1.342GluPhe: 1.342 ± 0.044
0.894GluGly: 0.894 ± 0.194
0.0GluHis: 0.0 ± 0.0
6.261GluIle: 6.261 ± 0.017
5.814GluLys: 5.814 ± 1.754
6.261GluLeu: 6.261 ± 0.652
1.789GluMet: 1.789 ± 0.387
3.131GluAsn: 3.131 ± 0.996
1.789GluPro: 1.789 ± 0.282
0.894GluGln: 0.894 ± 0.194
2.236GluArg: 2.236 ± 1.19
2.236GluSer: 2.236 ± 1.19
3.131GluThr: 3.131 ± 1.665
6.261GluVal: 6.261 ± 0.652
1.789GluTrp: 1.789 ± 0.952
0.894GluTyr: 0.894 ± 0.863
0.0GluXaa: 0.0 ± 0.0
Phe
1.789PheAla: 1.789 ± 0.282
0.0PheCys: 0.0 ± 0.0
4.025PheAsp: 4.025 ± 0.802
2.683PheGlu: 2.683 ± 1.251
1.789PhePhe: 1.789 ± 1.057
4.919PheGly: 4.919 ± 0.608
2.236PheHis: 2.236 ± 0.15
2.683PheIle: 2.683 ± 1.427
1.789PheLys: 1.789 ± 0.282
4.025PheLeu: 4.025 ± 0.537
0.447PheMet: 0.447 ± 0.238
3.131PheAsn: 3.131 ± 1.682
0.447PhePro: 0.447 ± 0.432
1.789PheGln: 1.789 ± 0.387
1.789PheArg: 1.789 ± 0.387
5.367PheSer: 5.367 ± 0.493
4.025PheThr: 4.025 ± 0.537
3.578PheVal: 3.578 ± 0.105
0.894PheTrp: 0.894 ± 0.476
0.894PheTyr: 0.894 ± 0.194
0.0PheXaa: 0.0 ± 0.0
Gly
5.814GlyAla: 5.814 ± 0.925
1.342GlyCys: 1.342 ± 0.625
3.578GlyAsp: 3.578 ± 0.564
4.472GlyGlu: 4.472 ± 1.638
2.236GlyPhe: 2.236 ± 0.819
4.472GlyGly: 4.472 ± 2.308
0.447GlyHis: 0.447 ± 0.238
3.131GlyIle: 3.131 ± 0.996
4.025GlyLys: 4.025 ± 0.537
3.578GlyLeu: 3.578 ± 0.564
1.789GlyMet: 1.789 ± 0.282
3.578GlyAsn: 3.578 ± 0.105
2.236GlyPro: 2.236 ± 0.15
1.789GlyGln: 1.789 ± 0.282
2.236GlyArg: 2.236 ± 0.15
4.025GlySer: 4.025 ± 2.141
3.131GlyThr: 3.131 ± 0.343
3.131GlyVal: 3.131 ± 0.326
0.894GlyTrp: 0.894 ± 0.863
2.683GlyTyr: 2.683 ± 0.581
0.0GlyXaa: 0.0 ± 0.0
His
0.894HisAla: 0.894 ± 0.194
0.894HisCys: 0.894 ± 0.476
0.0HisAsp: 0.0 ± 0.0
0.447HisGlu: 0.447 ± 0.238
0.0HisPhe: 0.0 ± 0.0
1.342HisGly: 1.342 ± 0.044
0.0HisHis: 0.0 ± 0.0
3.131HisIle: 3.131 ± 0.996
0.894HisLys: 0.894 ± 0.863
0.447HisLeu: 0.447 ± 0.238
0.447HisMet: 0.447 ± 0.238
0.447HisAsn: 0.447 ± 0.238
0.894HisPro: 0.894 ± 0.863
0.894HisGln: 0.894 ± 0.194
1.342HisArg: 1.342 ± 0.714
0.447HisSer: 0.447 ± 0.238
0.447HisThr: 0.447 ± 0.432
2.236HisVal: 2.236 ± 0.15
0.0HisTrp: 0.0 ± 0.0
0.447HisTyr: 0.447 ± 0.432
0.0HisXaa: 0.0 ± 0.0
Ile
3.578IleAla: 3.578 ± 0.564
2.683IleCys: 2.683 ± 0.581
3.578IleAsp: 3.578 ± 0.564
4.919IleGlu: 4.919 ± 1.278
2.683IlePhe: 2.683 ± 0.758
3.578IleGly: 3.578 ± 0.105
0.447IleHis: 0.447 ± 0.432
4.025IleIle: 4.025 ± 0.133
3.131IleLys: 3.131 ± 0.343
2.236IleLeu: 2.236 ± 0.52
1.342IleMet: 1.342 ± 0.625
2.236IleAsn: 2.236 ± 0.15
2.236IlePro: 2.236 ± 0.52
1.342IleGln: 1.342 ± 0.044
2.236IleArg: 2.236 ± 0.52
6.261IleSer: 6.261 ± 0.687
5.814IleThr: 5.814 ± 1.754
7.603IleVal: 7.603 ± 0.027
0.447IleTrp: 0.447 ± 0.238
2.236IleTyr: 2.236 ± 0.819
0.0IleXaa: 0.0 ± 0.0
Lys
3.131LysAla: 3.131 ± 0.996
1.342LysCys: 1.342 ± 0.714
4.472LysAsp: 4.472 ± 1.709
5.814LysGlu: 5.814 ± 1.084
4.025LysPhe: 4.025 ± 0.133
3.131LysGly: 3.131 ± 0.996
2.683LysHis: 2.683 ± 0.088
3.578LysIle: 3.578 ± 1.903
3.131LysLys: 3.131 ± 1.665
7.603LysLeu: 7.603 ± 0.642
1.342LysMet: 1.342 ± 0.714
1.342LysAsn: 1.342 ± 0.044
2.683LysPro: 2.683 ± 0.088
0.894LysGln: 0.894 ± 0.194
1.789LysArg: 1.789 ± 0.952
4.472LysSer: 4.472 ± 0.37
4.919LysThr: 4.919 ± 1.278
3.131LysVal: 3.131 ± 0.996
1.342LysTrp: 1.342 ± 0.625
2.683LysTyr: 2.683 ± 1.427
0.0LysXaa: 0.0 ± 0.0
Leu
6.261LeuAla: 6.261 ± 1.322
1.342LeuCys: 1.342 ± 0.714
5.814LeuAsp: 5.814 ± 0.255
4.472LeuGlu: 4.472 ± 0.37
3.131LeuPhe: 3.131 ± 1.013
1.342LeuGly: 1.342 ± 0.714
2.236LeuHis: 2.236 ± 0.52
0.894LeuIle: 0.894 ± 0.194
6.261LeuLys: 6.261 ± 1.992
4.919LeuLeu: 4.919 ± 0.061
1.789LeuMet: 1.789 ± 0.282
6.708LeuAsn: 6.708 ± 1.118
3.578LeuPro: 3.578 ± 0.775
0.894LeuGln: 0.894 ± 0.476
4.025LeuArg: 4.025 ± 0.537
5.814LeuSer: 5.814 ± 0.255
5.367LeuThr: 5.367 ± 1.832
6.708LeuVal: 6.708 ± 1.56
0.894LeuTrp: 0.894 ± 0.194
4.472LeuTyr: 4.472 ± 0.37
0.0LeuXaa: 0.0 ± 0.0
Met
2.236MetAla: 2.236 ± 1.19
1.789MetCys: 1.789 ± 0.282
2.236MetAsp: 2.236 ± 0.52
1.342MetGlu: 1.342 ± 0.044
1.789MetPhe: 1.789 ± 0.282
2.683MetGly: 2.683 ± 0.581
0.447MetHis: 0.447 ± 0.238
2.236MetIle: 2.236 ± 0.819
1.342MetLys: 1.342 ± 0.044
2.236MetLeu: 2.236 ± 0.819
0.0MetMet: 0.0 ± 0.0
0.894MetAsn: 0.894 ± 0.476
4.025MetPro: 4.025 ± 0.537
0.894MetGln: 0.894 ± 0.194
1.789MetArg: 1.789 ± 0.952
3.131MetSer: 3.131 ± 0.326
1.789MetThr: 1.789 ± 1.057
2.683MetVal: 2.683 ± 0.758
0.447MetTrp: 0.447 ± 0.432
0.447MetTyr: 0.447 ± 0.238
0.0MetXaa: 0.0 ± 0.0
Asn
1.789AsnAla: 1.789 ± 0.387
0.894AsnCys: 0.894 ± 0.476
5.814AsnAsp: 5.814 ± 0.255
2.236AsnGlu: 2.236 ± 0.52
0.447AsnPhe: 0.447 ± 0.238
3.131AsnGly: 3.131 ± 1.682
0.894AsnHis: 0.894 ± 0.476
2.683AsnIle: 2.683 ± 0.088
3.578AsnLys: 3.578 ± 0.105
2.236AsnLeu: 2.236 ± 0.15
2.236AsnMet: 2.236 ± 0.15
1.342AsnAsn: 1.342 ± 0.714
3.578AsnPro: 3.578 ± 0.775
0.894AsnGln: 0.894 ± 0.476
1.789AsnArg: 1.789 ± 0.282
5.367AsnSer: 5.367 ± 0.177
3.578AsnThr: 3.578 ± 2.114
2.683AsnVal: 2.683 ± 0.581
0.0AsnTrp: 0.0 ± 0.0
1.789AsnTyr: 1.789 ± 1.057
0.0AsnXaa: 0.0 ± 0.0
Pro
3.131ProAla: 3.131 ± 0.326
2.236ProCys: 2.236 ± 1.489
1.789ProAsp: 1.789 ± 0.282
0.894ProGlu: 0.894 ± 0.476
0.894ProPhe: 0.894 ± 0.863
1.789ProGly: 1.789 ± 0.282
0.447ProHis: 0.447 ± 0.432
4.025ProIle: 4.025 ± 0.133
1.342ProLys: 1.342 ± 0.044
3.131ProLeu: 3.131 ± 0.326
0.894ProMet: 0.894 ± 0.194
1.789ProAsn: 1.789 ± 0.282
2.236ProPro: 2.236 ± 0.15
1.789ProGln: 1.789 ± 0.387
1.342ProArg: 1.342 ± 0.625
5.814ProSer: 5.814 ± 0.255
4.025ProThr: 4.025 ± 0.537
3.131ProVal: 3.131 ± 1.013
1.789ProTrp: 1.789 ± 0.387
2.236ProTyr: 2.236 ± 1.489
0.0ProXaa: 0.0 ± 0.0
Gln
2.236GlnAla: 2.236 ± 0.819
0.447GlnCys: 0.447 ± 0.238
0.894GlnAsp: 0.894 ± 0.863
0.894GlnGlu: 0.894 ± 0.194
3.131GlnPhe: 3.131 ± 0.343
1.342GlnGly: 1.342 ± 0.625
0.0GlnHis: 0.0 ± 0.0
2.683GlnIle: 2.683 ± 0.581
2.236GlnLys: 2.236 ± 0.15
1.342GlnLeu: 1.342 ± 0.714
1.342GlnMet: 1.342 ± 0.625
1.342GlnAsn: 1.342 ± 0.044
0.0GlnPro: 0.0 ± 0.0
1.342GlnGln: 1.342 ± 0.044
0.447GlnArg: 0.447 ± 0.238
2.683GlnSer: 2.683 ± 0.581
1.342GlnThr: 1.342 ± 0.625
0.0GlnVal: 0.0 ± 0.0
1.342GlnTrp: 1.342 ± 0.714
0.894GlnTyr: 0.894 ± 0.476
0.0GlnXaa: 0.0 ± 0.0
Arg
3.131ArgAla: 3.131 ± 1.013
1.342ArgCys: 1.342 ± 0.044
2.683ArgAsp: 2.683 ± 0.758
1.789ArgGlu: 1.789 ± 0.387
4.472ArgPhe: 4.472 ± 0.37
2.236ArgGly: 2.236 ± 0.15
0.447ArgHis: 0.447 ± 0.238
1.789ArgIle: 1.789 ± 0.282
3.131ArgLys: 3.131 ± 0.996
2.236ArgLeu: 2.236 ± 0.15
2.683ArgMet: 2.683 ± 1.251
3.131ArgAsn: 3.131 ± 0.343
1.789ArgPro: 1.789 ± 0.387
0.447ArgGln: 0.447 ± 0.432
2.683ArgArg: 2.683 ± 0.088
1.789ArgSer: 1.789 ± 0.952
1.342ArgThr: 1.342 ± 0.044
2.683ArgVal: 2.683 ± 0.088
0.894ArgTrp: 0.894 ± 0.194
0.894ArgTyr: 0.894 ± 0.194
0.0ArgXaa: 0.0 ± 0.0
Ser
5.367SerAla: 5.367 ± 2.502
0.447SerCys: 0.447 ± 0.238
4.472SerAsp: 4.472 ± 0.299
4.919SerGlu: 4.919 ± 1.947
5.367SerPhe: 5.367 ± 0.493
6.261SerGly: 6.261 ± 0.687
1.342SerHis: 1.342 ± 0.044
4.919SerIle: 4.919 ± 0.608
4.025SerLys: 4.025 ± 1.472
5.367SerLeu: 5.367 ± 0.846
4.025SerMet: 4.025 ± 0.802
4.025SerAsn: 4.025 ± 2.546
4.025SerPro: 4.025 ± 0.133
3.578SerGln: 3.578 ± 2.114
4.472SerArg: 4.472 ± 2.977
4.472SerSer: 4.472 ± 1.04
4.472SerThr: 4.472 ± 0.969
5.814SerVal: 5.814 ± 0.255
0.447SerTrp: 0.447 ± 0.238
2.683SerTyr: 2.683 ± 0.088
0.0SerXaa: 0.0 ± 0.0
Thr
1.789ThrAla: 1.789 ± 1.057
0.0ThrCys: 0.0 ± 0.0
2.236ThrAsp: 2.236 ± 0.819
1.342ThrGlu: 1.342 ± 0.714
2.683ThrPhe: 2.683 ± 0.088
4.025ThrGly: 4.025 ± 0.802
0.894ThrHis: 0.894 ± 0.194
4.919ThrIle: 4.919 ± 0.061
4.472ThrLys: 4.472 ± 1.709
7.603ThrLeu: 7.603 ± 0.642
3.578ThrMet: 3.578 ± 0.277
4.025ThrAsn: 4.025 ± 0.802
4.472ThrPro: 4.472 ± 0.299
1.789ThrGln: 1.789 ± 0.387
1.789ThrArg: 1.789 ± 1.057
6.261ThrSer: 6.261 ± 2.026
5.814ThrThr: 5.814 ± 2.264
4.919ThrVal: 4.919 ± 1.4
0.447ThrTrp: 0.447 ± 0.238
0.894ThrTyr: 0.894 ± 0.194
0.0ThrXaa: 0.0 ± 0.0
Val
7.156ValAla: 7.156 ± 0.211
3.578ValCys: 3.578 ± 1.234
4.025ValAsp: 4.025 ± 0.537
3.578ValGlu: 3.578 ± 1.234
3.131ValPhe: 3.131 ± 1.013
4.919ValGly: 4.919 ± 1.4
0.0ValHis: 0.0 ± 0.0
1.789ValIle: 1.789 ± 0.387
4.919ValLys: 4.919 ± 1.947
4.919ValLeu: 4.919 ± 0.731
1.342ValMet: 1.342 ± 0.714
3.578ValAsn: 3.578 ± 0.775
3.578ValPro: 3.578 ± 0.105
1.342ValGln: 1.342 ± 0.044
3.578ValArg: 3.578 ± 0.105
6.708ValSer: 6.708 ± 1.118
4.025ValThr: 4.025 ± 0.802
1.789ValVal: 1.789 ± 0.952
0.894ValTrp: 0.894 ± 0.476
3.131ValTyr: 3.131 ± 1.665
0.0ValXaa: 0.0 ± 0.0
Trp
0.894TrpAla: 0.894 ± 0.194
0.0TrpCys: 0.0 ± 0.0
1.789TrpAsp: 1.789 ± 0.387
1.789TrpGlu: 1.789 ± 0.952
0.894TrpPhe: 0.894 ± 0.476
0.894TrpGly: 0.894 ± 0.194
0.0TrpHis: 0.0 ± 0.0
1.789TrpIle: 1.789 ± 0.952
1.789TrpLys: 1.789 ± 0.952
0.894TrpLeu: 0.894 ± 0.194
0.447TrpMet: 0.447 ± 0.238
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.894TrpGln: 0.894 ± 0.194
0.447TrpArg: 0.447 ± 0.432
1.342TrpSer: 1.342 ± 0.625
0.894TrpThr: 0.894 ± 0.194
0.447TrpVal: 0.447 ± 0.432
0.0TrpTrp: 0.0 ± 0.0
0.894TrpTyr: 0.894 ± 0.476
0.0TrpXaa: 0.0 ± 0.0
Tyr
5.814TyrAla: 5.814 ± 0.925
0.894TyrCys: 0.894 ± 0.476
4.025TyrAsp: 4.025 ± 0.802
1.342TyrGlu: 1.342 ± 0.625
2.683TyrPhe: 2.683 ± 0.581
4.025TyrGly: 4.025 ± 0.133
1.342TyrHis: 1.342 ± 0.044
3.131TyrIle: 3.131 ± 1.013
0.894TyrLys: 0.894 ± 0.476
1.789TyrLeu: 1.789 ± 0.387
1.342TyrMet: 1.342 ± 0.044
1.342TyrAsn: 1.342 ± 0.044
0.447TyrPro: 0.447 ± 0.238
1.789TyrGln: 1.789 ± 0.282
1.342TyrArg: 1.342 ± 0.044
3.131TyrSer: 3.131 ± 1.682
0.894TyrThr: 0.894 ± 0.194
1.789TyrVal: 1.789 ± 0.952
0.0TyrTrp: 0.0 ± 0.0
0.894TyrTyr: 0.894 ± 0.194
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2237 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski