Amino acid dipepetide frequency for Pineapple mealybug wilt-associated virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.037AlaAla: 5.037 ± 0.704
0.959AlaCys: 0.959 ± 0.587
3.358AlaAsp: 3.358 ± 0.775
3.838AlaGlu: 3.838 ± 0.66
1.679AlaPhe: 1.679 ± 0.592
4.557AlaGly: 4.557 ± 1.862
1.919AlaHis: 1.919 ± 0.657
4.557AlaIle: 4.557 ± 1.773
3.838AlaLys: 3.838 ± 0.971
8.635AlaLeu: 8.635 ± 0.66
0.48AlaMet: 0.48 ± 0.294
4.557AlaAsn: 4.557 ± 0.614
0.72AlaPro: 0.72 ± 0.415
0.959AlaGln: 0.959 ± 0.293
3.118AlaArg: 3.118 ± 0.866
3.358AlaSer: 3.358 ± 0.725
1.679AlaThr: 1.679 ± 1.404
6.716AlaVal: 6.716 ± 1.389
0.48AlaTrp: 0.48 ± 0.69
2.159AlaTyr: 2.159 ± 0.924
0.0AlaXaa: 0.0 ± 0.0
Cys
2.159CysAla: 2.159 ± 0.518
0.0CysCys: 0.0 ± 0.0
0.48CysAsp: 0.48 ± 0.416
0.48CysGlu: 0.48 ± 0.294
0.959CysPhe: 0.959 ± 0.481
0.48CysGly: 0.48 ± 0.245
0.24CysHis: 0.24 ± 0.147
0.72CysIle: 0.72 ± 0.286
2.639CysLys: 2.639 ± 0.798
1.199CysLeu: 1.199 ± 0.46
0.0CysMet: 0.0 ± 0.0
0.72CysAsn: 0.72 ± 0.441
0.72CysPro: 0.72 ± 0.286
0.0CysGln: 0.0 ± 0.0
0.72CysArg: 0.72 ± 0.286
1.199CysSer: 1.199 ± 0.4
0.72CysThr: 0.72 ± 0.944
1.919CysVal: 1.919 ± 0.443
0.48CysTrp: 0.48 ± 0.294
0.24CysTyr: 0.24 ± 0.147
0.0CysXaa: 0.0 ± 0.0
Asp
3.118AspAla: 3.118 ± 0.889
0.959AspCys: 0.959 ± 0.432
3.598AspAsp: 3.598 ± 0.462
3.118AspGlu: 3.118 ± 0.659
3.358AspPhe: 3.358 ± 1.289
2.878AspGly: 2.878 ± 0.644
0.24AspHis: 0.24 ± 0.147
3.358AspIle: 3.358 ± 0.591
2.639AspLys: 2.639 ± 0.753
5.757AspLeu: 5.757 ± 1.27
0.959AspMet: 0.959 ± 0.71
2.399AspAsn: 2.399 ± 1.181
1.439AspPro: 1.439 ± 0.64
1.439AspGln: 1.439 ± 0.409
4.318AspArg: 4.318 ± 1.24
6.476AspSer: 6.476 ± 0.835
2.399AspThr: 2.399 ± 0.527
5.517AspVal: 5.517 ± 1.396
0.959AspTrp: 0.959 ± 0.293
0.959AspTyr: 0.959 ± 0.693
0.0AspXaa: 0.0 ± 0.0
Glu
3.118GluAla: 3.118 ± 0.535
0.959GluCys: 0.959 ± 0.367
2.878GluAsp: 2.878 ± 0.844
4.797GluGlu: 4.797 ± 1.128
1.919GluPhe: 1.919 ± 0.588
3.358GluGly: 3.358 ± 1.095
2.159GluHis: 2.159 ± 0.782
4.797GluIle: 4.797 ± 0.793
3.598GluLys: 3.598 ± 0.785
5.997GluLeu: 5.997 ± 1.036
0.959GluMet: 0.959 ± 0.289
3.598GluAsn: 3.598 ± 0.534
0.72GluPro: 0.72 ± 0.29
2.159GluGln: 2.159 ± 0.96
2.878GluArg: 2.878 ± 0.523
5.757GluSer: 5.757 ± 0.797
2.399GluThr: 2.399 ± 0.941
6.237GluVal: 6.237 ± 1.183
0.0GluTrp: 0.0 ± 0.0
1.439GluTyr: 1.439 ± 0.606
0.0GluXaa: 0.0 ± 0.0
Phe
2.399PheAla: 2.399 ± 0.993
1.679PheCys: 1.679 ± 0.509
3.838PheAsp: 3.838 ± 1.324
3.358PheGlu: 3.358 ± 0.833
2.159PhePhe: 2.159 ± 0.819
2.878PheGly: 2.878 ± 0.836
0.48PheHis: 0.48 ± 0.245
2.878PheIle: 2.878 ± 0.956
3.118PheLys: 3.118 ± 1.01
3.598PheLeu: 3.598 ± 1.011
1.439PheMet: 1.439 ± 0.439
3.358PheAsn: 3.358 ± 0.952
1.199PhePro: 1.199 ± 0.509
1.439PheGln: 1.439 ± 0.652
0.959PheArg: 0.959 ± 0.295
5.517PheSer: 5.517 ± 1.199
2.399PheThr: 2.399 ± 0.732
2.878PheVal: 2.878 ± 0.73
0.0PheTrp: 0.0 ± 0.0
1.919PheTyr: 1.919 ± 0.696
0.0PheXaa: 0.0 ± 0.0
Gly
3.358GlyAla: 3.358 ± 0.791
0.48GlyCys: 0.48 ± 0.556
3.118GlyAsp: 3.118 ± 0.744
4.797GlyGlu: 4.797 ± 1.006
2.399GlyPhe: 2.399 ± 0.74
4.318GlyGly: 4.318 ± 2.058
0.72GlyHis: 0.72 ± 0.343
3.118GlyIle: 3.118 ± 0.88
5.757GlyLys: 5.757 ± 1.465
5.277GlyLeu: 5.277 ± 0.808
1.199GlyMet: 1.199 ± 0.335
2.639GlyAsn: 2.639 ± 0.621
2.159GlyPro: 2.159 ± 0.702
0.959GlyGln: 0.959 ± 0.434
4.078GlyArg: 4.078 ± 1.083
5.037GlySer: 5.037 ± 0.651
1.919GlyThr: 1.919 ± 0.635
4.078GlyVal: 4.078 ± 0.48
0.48GlyTrp: 0.48 ± 0.287
1.919GlyTyr: 1.919 ± 0.573
0.0GlyXaa: 0.0 ± 0.0
His
1.439HisAla: 1.439 ± 0.425
0.24HisCys: 0.24 ± 0.33
1.439HisAsp: 1.439 ± 0.699
1.199HisGlu: 1.199 ± 0.391
0.959HisPhe: 0.959 ± 0.489
1.439HisGly: 1.439 ± 0.701
0.24HisHis: 0.24 ± 0.345
0.72HisIle: 0.72 ± 0.453
2.159HisLys: 2.159 ± 0.867
1.919HisLeu: 1.919 ± 1.515
0.48HisMet: 0.48 ± 0.413
0.48HisAsn: 0.48 ± 0.413
0.72HisPro: 0.72 ± 0.29
0.24HisGln: 0.24 ± 0.147
0.959HisArg: 0.959 ± 0.372
0.959HisSer: 0.959 ± 0.295
1.199HisThr: 1.199 ± 0.481
1.199HisVal: 1.199 ± 0.391
0.0HisTrp: 0.0 ± 0.0
0.72HisTyr: 0.72 ± 0.298
0.0HisXaa: 0.0 ± 0.0
Ile
1.439IleAla: 1.439 ± 1.015
1.199IleCys: 1.199 ± 0.533
3.838IleAsp: 3.838 ± 1.633
2.399IleGlu: 2.399 ± 0.442
3.598IlePhe: 3.598 ± 1.248
3.358IleGly: 3.358 ± 0.985
0.48IleHis: 0.48 ± 0.287
1.679IleIle: 1.679 ± 1.038
3.358IleLys: 3.358 ± 0.811
5.277IleLeu: 5.277 ± 1.246
1.199IleMet: 1.199 ± 0.507
2.878IleAsn: 2.878 ± 0.781
3.598IlePro: 3.598 ± 0.45
1.679IleGln: 1.679 ± 0.456
2.159IleArg: 2.159 ± 0.63
3.838IleSer: 3.838 ± 0.646
2.878IleThr: 2.878 ± 0.823
4.557IleVal: 4.557 ± 0.662
0.24IleTrp: 0.24 ± 0.246
0.959IleTyr: 0.959 ± 0.539
0.0IleXaa: 0.0 ± 0.0
Lys
6.476LysAla: 6.476 ± 1.564
0.48LysCys: 0.48 ± 0.241
4.078LysAsp: 4.078 ± 0.411
2.639LysGlu: 2.639 ± 0.683
3.598LysPhe: 3.598 ± 0.881
3.838LysGly: 3.838 ± 1.076
1.679LysHis: 1.679 ± 0.854
3.358LysIle: 3.358 ± 0.766
2.639LysLys: 2.639 ± 0.786
5.997LysLeu: 5.997 ± 0.736
1.679LysMet: 1.679 ± 0.351
2.639LysAsn: 2.639 ± 0.283
3.358LysPro: 3.358 ± 1.347
1.919LysGln: 1.919 ± 0.755
3.838LysArg: 3.838 ± 1.174
4.557LysSer: 4.557 ± 1.028
5.757LysThr: 5.757 ± 0.719
6.237LysVal: 6.237 ± 0.99
0.72LysTrp: 0.72 ± 0.32
2.878LysTyr: 2.878 ± 0.82
0.0LysXaa: 0.0 ± 0.0
Leu
5.517LeuAla: 5.517 ± 2.299
1.439LeuCys: 1.439 ± 0.42
4.797LeuAsp: 4.797 ± 1.196
5.277LeuGlu: 5.277 ± 0.824
4.318LeuPhe: 4.318 ± 1.147
4.797LeuGly: 4.797 ± 1.215
0.959LeuHis: 0.959 ± 0.483
4.797LeuIle: 4.797 ± 1.248
9.834LeuLys: 9.834 ± 2.627
8.875LeuLeu: 8.875 ± 2.22
2.159LeuMet: 2.159 ± 0.781
5.517LeuAsn: 5.517 ± 0.947
5.277LeuPro: 5.277 ± 1.648
2.159LeuGln: 2.159 ± 0.667
5.277LeuArg: 5.277 ± 1.521
8.875LeuSer: 8.875 ± 1.139
4.318LeuThr: 4.318 ± 1.076
7.916LeuVal: 7.916 ± 1.317
1.679LeuTrp: 1.679 ± 1.153
2.399LeuTyr: 2.399 ± 0.433
0.0LeuXaa: 0.0 ± 0.0
Met
2.159MetAla: 2.159 ± 1.323
0.72MetCys: 0.72 ± 0.417
0.24MetAsp: 0.24 ± 0.345
1.199MetGlu: 1.199 ± 0.623
0.72MetPhe: 0.72 ± 0.441
1.199MetGly: 1.199 ± 0.877
0.48MetHis: 0.48 ± 0.69
0.959MetIle: 0.959 ± 0.909
0.72MetLys: 0.72 ± 0.441
1.919MetLeu: 1.919 ± 0.477
1.199MetMet: 1.199 ± 0.711
1.199MetAsn: 1.199 ± 0.45
1.199MetPro: 1.199 ± 0.362
0.48MetGln: 0.48 ± 0.56
1.679MetArg: 1.679 ± 0.43
1.199MetSer: 1.199 ± 0.563
2.399MetThr: 2.399 ± 0.723
2.399MetVal: 2.399 ± 0.503
0.0MetTrp: 0.0 ± 0.0
0.24MetTyr: 0.24 ± 0.345
0.0MetXaa: 0.0 ± 0.0
Asn
3.118AsnAla: 3.118 ± 0.727
1.199AsnCys: 1.199 ± 0.563
1.679AsnAsp: 1.679 ± 0.509
3.838AsnGlu: 3.838 ± 1.088
2.399AsnPhe: 2.399 ± 1.241
1.679AsnGly: 1.679 ± 0.529
0.959AsnHis: 0.959 ± 0.295
2.639AsnIle: 2.639 ± 1.639
4.078AsnLys: 4.078 ± 1.04
5.277AsnLeu: 5.277 ± 0.847
1.199AsnMet: 1.199 ± 1.067
2.159AsnAsn: 2.159 ± 0.684
3.838AsnPro: 3.838 ± 0.543
1.199AsnGln: 1.199 ± 0.264
4.557AsnArg: 4.557 ± 1.121
3.838AsnSer: 3.838 ± 0.782
3.598AsnThr: 3.598 ± 0.504
4.557AsnVal: 4.557 ± 1.307
0.24AsnTrp: 0.24 ± 0.147
2.399AsnTyr: 2.399 ± 1.14
0.0AsnXaa: 0.0 ± 0.0
Pro
1.679ProAla: 1.679 ± 0.375
0.24ProCys: 0.24 ± 0.246
1.919ProAsp: 1.919 ± 0.534
4.078ProGlu: 4.078 ± 0.582
1.199ProPhe: 1.199 ± 0.264
2.399ProGly: 2.399 ± 1.001
1.679ProHis: 1.679 ± 0.659
2.639ProIle: 2.639 ± 0.513
2.399ProLys: 2.399 ± 0.994
2.878ProLeu: 2.878 ± 0.94
0.959ProMet: 0.959 ± 0.506
3.118ProAsn: 3.118 ± 0.863
2.159ProPro: 2.159 ± 0.386
0.48ProGln: 0.48 ± 0.294
2.399ProArg: 2.399 ± 0.874
1.919ProSer: 1.919 ± 0.772
2.399ProThr: 2.399 ± 0.716
4.318ProVal: 4.318 ± 0.798
0.24ProTrp: 0.24 ± 0.147
0.72ProTyr: 0.72 ± 0.339
0.0ProXaa: 0.0 ± 0.0
Gln
1.679GlnAla: 1.679 ± 0.781
0.48GlnCys: 0.48 ± 0.294
1.199GlnAsp: 1.199 ± 0.45
1.439GlnGlu: 1.439 ± 0.881
1.919GlnPhe: 1.919 ± 0.863
1.199GlnGly: 1.199 ± 0.43
0.0GlnHis: 0.0 ± 0.0
0.959GlnIle: 0.959 ± 0.295
0.959GlnLys: 0.959 ± 0.529
1.919GlnLeu: 1.919 ± 0.377
0.72GlnMet: 0.72 ± 0.54
1.919GlnAsn: 1.919 ± 0.453
0.72GlnPro: 0.72 ± 0.453
1.199GlnGln: 1.199 ± 0.569
1.919GlnArg: 1.919 ± 0.539
2.639GlnSer: 2.639 ± 0.857
1.919GlnThr: 1.919 ± 0.921
1.679GlnVal: 1.679 ± 0.589
0.48GlnTrp: 0.48 ± 0.245
0.959GlnTyr: 0.959 ± 0.372
0.0GlnXaa: 0.0 ± 0.0
Arg
4.078ArgAla: 4.078 ± 0.933
0.72ArgCys: 0.72 ± 0.441
2.639ArgAsp: 2.639 ± 0.784
3.358ArgGlu: 3.358 ± 1.257
3.598ArgPhe: 3.598 ± 0.784
3.598ArgGly: 3.598 ± 0.611
0.48ArgHis: 0.48 ± 0.287
3.118ArgIle: 3.118 ± 0.879
2.878ArgLys: 2.878 ± 0.433
6.476ArgLeu: 6.476 ± 1.848
1.919ArgMet: 1.919 ± 0.871
3.358ArgAsn: 3.358 ± 0.671
1.439ArgPro: 1.439 ± 0.483
1.679ArgGln: 1.679 ± 0.552
6.237ArgArg: 6.237 ± 1.821
5.277ArgSer: 5.277 ± 1.108
2.878ArgThr: 2.878 ± 1.012
4.078ArgVal: 4.078 ± 1.109
0.24ArgTrp: 0.24 ± 0.147
1.919ArgTyr: 1.919 ± 1.314
0.0ArgXaa: 0.0 ± 0.0
Ser
4.318SerAla: 4.318 ± 0.785
0.72SerCys: 0.72 ± 0.391
4.797SerAsp: 4.797 ± 0.826
5.277SerGlu: 5.277 ± 0.83
4.318SerPhe: 4.318 ± 1.41
5.997SerGly: 5.997 ± 1.674
1.679SerHis: 1.679 ± 1.028
1.679SerIle: 1.679 ± 0.786
6.476SerLys: 6.476 ± 1.028
8.155SerLeu: 8.155 ± 0.795
1.679SerMet: 1.679 ± 0.693
3.838SerAsn: 3.838 ± 0.725
3.118SerPro: 3.118 ± 0.781
2.639SerGln: 2.639 ± 1.18
4.797SerArg: 4.797 ± 0.901
9.595SerSer: 9.595 ± 1.574
5.037SerThr: 5.037 ± 1.713
8.395SerVal: 8.395 ± 2.009
0.0SerTrp: 0.0 ± 0.0
3.118SerTyr: 3.118 ± 0.634
0.0SerXaa: 0.0 ± 0.0
Thr
3.358ThrAla: 3.358 ± 1.365
0.24ThrCys: 0.24 ± 0.147
3.118ThrAsp: 3.118 ± 1.167
1.439ThrGlu: 1.439 ± 0.42
3.598ThrPhe: 3.598 ± 1.503
1.919ThrGly: 1.919 ± 0.468
1.199ThrHis: 1.199 ± 0.45
3.118ThrIle: 3.118 ± 0.336
2.159ThrLys: 2.159 ± 0.835
6.716ThrLeu: 6.716 ± 1.65
1.439ThrMet: 1.439 ± 0.642
3.118ThrAsn: 3.118 ± 0.535
1.439ThrPro: 1.439 ± 0.539
1.919ThrGln: 1.919 ± 0.803
2.399ThrArg: 2.399 ± 0.597
3.358ThrSer: 3.358 ± 0.61
2.399ThrThr: 2.399 ± 0.9
3.838ThrVal: 3.838 ± 0.607
0.48ThrTrp: 0.48 ± 0.401
1.919ThrTyr: 1.919 ± 0.802
0.0ThrXaa: 0.0 ± 0.0
Val
5.757ValAla: 5.757 ± 1.357
2.878ValCys: 2.878 ± 0.869
6.476ValAsp: 6.476 ± 0.969
5.517ValGlu: 5.517 ± 0.825
2.159ValPhe: 2.159 ± 0.601
5.037ValGly: 5.037 ± 1.312
2.639ValHis: 2.639 ± 0.453
2.878ValIle: 2.878 ± 0.595
6.956ValLys: 6.956 ± 1.179
6.476ValLeu: 6.476 ± 1.185
1.679ValMet: 1.679 ± 0.559
5.757ValAsn: 5.757 ± 0.912
4.318ValPro: 4.318 ± 1.662
2.159ValGln: 2.159 ± 0.702
5.037ValArg: 5.037 ± 2.301
7.916ValSer: 7.916 ± 1.126
2.159ValThr: 2.159 ± 1.074
11.034ValVal: 11.034 ± 1.351
0.24ValTrp: 0.24 ± 0.147
3.358ValTyr: 3.358 ± 0.803
0.0ValXaa: 0.0 ± 0.0
Trp
0.959TrpAla: 0.959 ± 0.409
0.24TrpCys: 0.24 ± 0.345
0.0TrpAsp: 0.0 ± 0.0
0.24TrpGlu: 0.24 ± 0.458
0.72TrpPhe: 0.72 ± 0.32
0.72TrpGly: 0.72 ± 0.391
0.24TrpHis: 0.24 ± 0.246
0.48TrpIle: 0.48 ± 0.245
0.24TrpLys: 0.24 ± 0.147
0.48TrpLeu: 0.48 ± 0.245
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.24TrpPro: 0.24 ± 0.392
0.48TrpGln: 0.48 ± 0.401
0.72TrpArg: 0.72 ± 0.298
0.48TrpSer: 0.48 ± 0.69
0.24TrpThr: 0.24 ± 0.147
0.24TrpVal: 0.24 ± 0.246
0.24TrpTrp: 0.24 ± 0.345
0.24TrpTyr: 0.24 ± 0.147
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.439TyrAla: 1.439 ± 0.616
0.24TyrCys: 0.24 ± 0.147
2.399TyrAsp: 2.399 ± 1.137
1.439TyrGlu: 1.439 ± 0.866
1.919TyrPhe: 1.919 ± 0.385
2.159TyrGly: 2.159 ± 0.991
0.24TyrHis: 0.24 ± 0.147
2.159TyrIle: 2.159 ± 1.017
1.919TyrLys: 1.919 ± 0.62
3.358TyrLeu: 3.358 ± 1.265
0.72TyrMet: 0.72 ± 0.507
1.199TyrAsn: 1.199 ± 0.362
1.439TyrPro: 1.439 ± 0.365
0.72TyrGln: 0.72 ± 0.343
1.919TyrArg: 1.919 ± 0.972
3.838TyrSer: 3.838 ± 0.657
0.48TyrThr: 0.48 ± 0.401
2.878TyrVal: 2.878 ± 0.977
0.0TyrTrp: 0.0 ± 0.0
1.199TyrTyr: 1.199 ± 0.391
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (4170 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski