Amino acid dipepetide frequency for Beihai picorna-like virus 39

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.784AlaAla: 3.784 ± 0.723
0.0AlaCys: 0.0 ± 0.0
4.919AlaAsp: 4.919 ± 1.301
6.054AlaGlu: 6.054 ± 0.071
2.27AlaPhe: 2.27 ± 0.554
4.54AlaGly: 4.54 ± 0.7
2.27AlaHis: 2.27 ± 0.049
4.54AlaIle: 4.54 ± 1.109
4.54AlaLys: 4.54 ± 0.506
6.432AlaLeu: 6.432 ± 1.47
2.649AlaMet: 2.649 ± 0.459
2.649AlaAsn: 2.649 ± 0.747
4.54AlaPro: 4.54 ± 0.7
1.135AlaGln: 1.135 ± 0.579
3.405AlaArg: 3.405 ± 0.676
4.54AlaSer: 4.54 ± 2.509
2.649AlaThr: 2.649 ± 0.144
3.405AlaVal: 3.405 ± 0.53
1.135AlaTrp: 1.135 ± 0.627
1.892AlaTyr: 1.892 ± 0.361
0.0AlaXaa: 0.0 ± 0.0
Cys
1.892CysAla: 1.892 ± 0.361
0.0CysCys: 0.0 ± 0.0
1.135CysAsp: 1.135 ± 0.579
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
2.649CysGly: 2.649 ± 0.747
1.135CysHis: 1.135 ± 0.579
0.0CysIle: 0.0 ± 0.0
0.757CysLys: 0.757 ± 0.217
1.135CysLeu: 1.135 ± 0.579
0.378CysMet: 0.378 ± 0.193
0.378CysAsn: 0.378 ± 0.193
0.757CysPro: 0.757 ± 0.386
0.378CysGln: 0.378 ± 0.41
0.378CysArg: 0.378 ± 0.193
1.513CysSer: 1.513 ± 0.169
0.378CysThr: 0.378 ± 0.193
1.513CysVal: 1.513 ± 0.771
0.0CysTrp: 0.0 ± 0.0
0.757CysTyr: 0.757 ± 0.217
0.0CysXaa: 0.0 ± 0.0
Asp
4.54AspAla: 4.54 ± 1.109
0.757AspCys: 0.757 ± 0.386
5.297AspAsp: 5.297 ± 1.494
3.405AspGlu: 3.405 ± 0.53
4.162AspPhe: 4.162 ± 1.519
4.54AspGly: 4.54 ± 0.506
0.378AspHis: 0.378 ± 0.193
3.784AspIle: 3.784 ± 0.483
1.513AspLys: 1.513 ± 0.169
5.297AspLeu: 5.297 ± 0.891
2.27AspMet: 2.27 ± 0.554
4.919AspAsn: 4.919 ± 2.316
4.919AspPro: 4.919 ± 1.713
1.135AspGln: 1.135 ± 0.627
1.513AspArg: 1.513 ± 0.169
3.027AspSer: 3.027 ± 0.266
2.649AspThr: 2.649 ± 1.061
5.297AspVal: 5.297 ± 1.494
1.135AspTrp: 1.135 ± 0.579
2.27AspTyr: 2.27 ± 0.049
0.0AspXaa: 0.0 ± 0.0
Glu
3.405GluAla: 3.405 ± 1.133
1.135GluCys: 1.135 ± 0.024
3.405GluAsp: 3.405 ± 1.279
3.405GluGlu: 3.405 ± 0.073
4.919GluPhe: 4.919 ± 0.096
3.784GluGly: 3.784 ± 1.326
1.513GluHis: 1.513 ± 0.771
3.405GluIle: 3.405 ± 0.53
4.54GluLys: 4.54 ± 1.711
6.81GluLeu: 6.81 ± 1.352
3.784GluMet: 3.784 ± 1.326
3.784GluAsn: 3.784 ± 0.12
2.649GluPro: 2.649 ± 0.459
1.135GluGln: 1.135 ± 0.024
4.162GluArg: 4.162 ± 0.29
4.919GluSer: 4.919 ± 0.096
1.135GluThr: 1.135 ± 0.024
3.405GluVal: 3.405 ± 0.53
0.757GluTrp: 0.757 ± 0.82
1.892GluTyr: 1.892 ± 0.361
0.0GluXaa: 0.0 ± 0.0
Phe
2.649PheAla: 2.649 ± 1.061
1.892PheCys: 1.892 ± 0.241
3.405PheAsp: 3.405 ± 1.133
2.649PheGlu: 2.649 ± 0.747
1.513PhePhe: 1.513 ± 1.037
3.784PheGly: 3.784 ± 0.483
2.27PheHis: 2.27 ± 0.049
4.162PheIle: 4.162 ± 0.313
2.27PheLys: 2.27 ± 0.554
2.649PheLeu: 2.649 ± 0.144
0.0PheMet: 0.0 ± 0.0
2.649PheAsn: 2.649 ± 0.144
2.649PhePro: 2.649 ± 0.747
1.513PheGln: 1.513 ± 0.169
3.784PheArg: 3.784 ± 0.12
6.432PheSer: 6.432 ± 1.544
1.892PheThr: 1.892 ± 0.241
1.513PheVal: 1.513 ± 0.169
0.0PheTrp: 0.0 ± 0.0
2.27PheTyr: 2.27 ± 0.049
0.0PheXaa: 0.0 ± 0.0
Gly
4.54GlyAla: 4.54 ± 0.506
0.757GlyCys: 0.757 ± 0.386
4.162GlyAsp: 4.162 ± 0.916
2.27GlyGlu: 2.27 ± 0.049
3.027GlyPhe: 3.027 ± 0.94
3.405GlyGly: 3.405 ± 0.073
1.513GlyHis: 1.513 ± 0.771
3.405GlyIle: 3.405 ± 0.53
4.919GlyLys: 4.919 ± 0.507
5.297GlyLeu: 5.297 ± 0.289
1.135GlyMet: 1.135 ± 0.024
3.405GlyAsn: 3.405 ± 1.279
2.649GlyPro: 2.649 ± 0.144
3.027GlyGln: 3.027 ± 1.543
2.649GlyArg: 2.649 ± 1.061
1.892GlySer: 1.892 ± 0.361
1.513GlyThr: 1.513 ± 1.64
6.432GlyVal: 6.432 ± 0.867
1.513GlyTrp: 1.513 ± 1.037
3.027GlyTyr: 3.027 ± 1.472
0.0GlyXaa: 0.0 ± 0.0
His
1.513HisAla: 1.513 ± 0.169
0.757HisCys: 0.757 ± 0.386
1.513HisAsp: 1.513 ± 0.169
0.757HisGlu: 0.757 ± 0.386
1.135HisPhe: 1.135 ± 0.579
0.757HisGly: 0.757 ± 0.217
1.135HisHis: 1.135 ± 0.024
2.27HisIle: 2.27 ± 0.049
1.513HisLys: 1.513 ± 0.169
1.892HisLeu: 1.892 ± 0.241
1.513HisMet: 1.513 ± 0.771
1.892HisAsn: 1.892 ± 0.361
3.027HisPro: 3.027 ± 0.94
1.135HisGln: 1.135 ± 0.024
1.135HisArg: 1.135 ± 0.579
2.649HisSer: 2.649 ± 0.747
0.757HisThr: 0.757 ± 0.217
2.27HisVal: 2.27 ± 0.554
0.0HisTrp: 0.0 ± 0.0
0.757HisTyr: 0.757 ± 0.386
0.0HisXaa: 0.0 ± 0.0
Ile
6.432IleAla: 6.432 ± 0.867
2.649IleCys: 2.649 ± 1.35
3.027IleAsp: 3.027 ± 0.869
4.54IleGlu: 4.54 ± 1.109
3.027IlePhe: 3.027 ± 0.337
3.405IleGly: 3.405 ± 0.676
1.892IleHis: 1.892 ± 0.241
1.513IleIle: 1.513 ± 0.169
3.027IleLys: 3.027 ± 0.266
4.162IleLeu: 4.162 ± 1.519
0.757IleMet: 0.757 ± 0.319
4.54IleAsn: 4.54 ± 0.097
2.649IlePro: 2.649 ± 1.061
1.892IleGln: 1.892 ± 0.964
2.649IleArg: 2.649 ± 1.35
4.919IleSer: 4.919 ± 2.316
2.27IleThr: 2.27 ± 0.049
4.919IleVal: 4.919 ± 0.507
0.0IleTrp: 0.0 ± 0.0
0.757IleTyr: 0.757 ± 0.217
0.0IleXaa: 0.0 ± 0.0
Lys
3.405LysAla: 3.405 ± 0.53
1.135LysCys: 1.135 ± 0.579
2.649LysAsp: 2.649 ± 1.35
3.405LysGlu: 3.405 ± 0.073
1.892LysPhe: 1.892 ± 0.241
3.405LysGly: 3.405 ± 0.53
1.135LysHis: 1.135 ± 0.579
4.162LysIle: 4.162 ± 0.29
4.54LysLys: 4.54 ± 1.711
2.649LysLeu: 2.649 ± 0.144
1.513LysMet: 1.513 ± 1.037
0.757LysAsn: 0.757 ± 0.217
2.649LysPro: 2.649 ± 1.35
3.027LysGln: 3.027 ± 1.543
2.649LysArg: 2.649 ± 0.747
3.784LysSer: 3.784 ± 1.326
2.649LysThr: 2.649 ± 0.144
4.162LysVal: 4.162 ± 0.916
0.0LysTrp: 0.0 ± 0.0
3.027LysTyr: 3.027 ± 1.543
0.0LysXaa: 0.0 ± 0.0
Leu
7.567LeuAla: 7.567 ± 0.843
0.0LeuCys: 0.0 ± 0.0
4.54LeuAsp: 4.54 ± 0.506
7.189LeuGlu: 7.189 ± 0.047
4.919LeuPhe: 4.919 ± 0.096
2.27LeuGly: 2.27 ± 0.049
3.405LeuHis: 3.405 ± 0.53
4.54LeuIle: 4.54 ± 0.506
3.405LeuLys: 3.405 ± 1.736
5.297LeuLeu: 5.297 ± 0.289
1.513LeuMet: 1.513 ± 0.771
5.675LeuAsn: 5.675 ± 0.481
4.919LeuPro: 4.919 ± 0.507
3.405LeuGln: 3.405 ± 0.53
1.892LeuArg: 1.892 ± 0.241
6.432LeuSer: 6.432 ± 0.942
6.432LeuThr: 6.432 ± 0.339
3.784LeuVal: 3.784 ± 0.723
1.135LeuTrp: 1.135 ± 1.23
1.892LeuTyr: 1.892 ± 0.361
0.0LeuXaa: 0.0 ± 0.0
Met
2.649MetAla: 2.649 ± 1.061
0.378MetCys: 0.378 ± 0.193
0.757MetAsp: 0.757 ± 0.386
2.649MetGlu: 2.649 ± 0.144
1.892MetPhe: 1.892 ± 0.361
1.135MetGly: 1.135 ± 0.579
0.757MetHis: 0.757 ± 0.386
1.135MetIle: 1.135 ± 0.627
1.892MetLys: 1.892 ± 0.361
2.649MetLeu: 2.649 ± 0.747
0.757MetMet: 0.757 ± 0.386
0.757MetAsn: 0.757 ± 0.217
0.757MetPro: 0.757 ± 0.217
1.513MetGln: 1.513 ± 0.169
1.513MetArg: 1.513 ± 0.169
1.513MetSer: 1.513 ± 0.169
0.757MetThr: 0.757 ± 0.386
1.135MetVal: 1.135 ± 0.024
0.757MetTrp: 0.757 ± 0.217
1.135MetTyr: 1.135 ± 0.579
0.0MetXaa: 0.0 ± 0.0
Asn
3.027AsnAla: 3.027 ± 0.266
0.757AsnCys: 0.757 ± 0.386
1.892AsnAsp: 1.892 ± 0.241
2.649AsnGlu: 2.649 ± 1.061
4.162AsnPhe: 4.162 ± 2.099
4.919AsnGly: 4.919 ± 0.096
1.513AsnHis: 1.513 ± 0.771
2.27AsnIle: 2.27 ± 0.049
1.513AsnLys: 1.513 ± 0.771
3.784AsnLeu: 3.784 ± 0.12
2.27AsnMet: 2.27 ± 1.157
2.27AsnAsn: 2.27 ± 0.554
3.784AsnPro: 3.784 ± 0.723
1.513AsnGln: 1.513 ± 1.64
2.27AsnArg: 2.27 ± 0.554
3.027AsnSer: 3.027 ± 2.074
3.784AsnThr: 3.784 ± 0.483
4.162AsnVal: 4.162 ± 2.099
0.757AsnTrp: 0.757 ± 0.386
0.378AsnTyr: 0.378 ± 0.193
0.0AsnXaa: 0.0 ± 0.0
Pro
2.27ProAla: 2.27 ± 0.554
0.757ProCys: 0.757 ± 0.217
3.784ProAsp: 3.784 ± 0.12
4.919ProGlu: 4.919 ± 1.11
3.027ProPhe: 3.027 ± 1.472
1.135ProGly: 1.135 ± 0.627
0.757ProHis: 0.757 ± 0.217
3.784ProIle: 3.784 ± 1.326
2.649ProLys: 2.649 ± 1.35
4.919ProLeu: 4.919 ± 0.699
1.135ProMet: 1.135 ± 0.627
0.757ProAsn: 0.757 ± 0.386
2.649ProPro: 2.649 ± 0.459
3.027ProGln: 3.027 ± 0.869
3.027ProArg: 3.027 ± 2.074
5.297ProSer: 5.297 ± 0.917
3.027ProThr: 3.027 ± 1.472
4.54ProVal: 4.54 ± 1.906
1.513ProTrp: 1.513 ± 0.434
0.757ProTyr: 0.757 ± 0.82
0.0ProXaa: 0.0 ± 0.0
Gln
1.892GlnAla: 1.892 ± 0.361
0.0GlnCys: 0.0 ± 0.0
4.919GlnAsp: 4.919 ± 0.507
1.513GlnGlu: 1.513 ± 0.434
1.513GlnPhe: 1.513 ± 0.169
3.784GlnGly: 3.784 ± 0.723
1.135GlnHis: 1.135 ± 0.579
1.135GlnIle: 1.135 ± 0.024
0.757GlnLys: 0.757 ± 0.386
3.405GlnLeu: 3.405 ± 0.073
0.757GlnMet: 0.757 ± 0.228
1.513GlnAsn: 1.513 ± 0.434
0.757GlnPro: 0.757 ± 0.217
0.378GlnGln: 0.378 ± 0.193
2.649GlnArg: 2.649 ± 0.144
3.405GlnSer: 3.405 ± 1.279
1.135GlnThr: 1.135 ± 0.024
1.513GlnVal: 1.513 ± 0.169
0.378GlnTrp: 0.378 ± 0.193
0.757GlnTyr: 0.757 ± 0.386
0.0GlnXaa: 0.0 ± 0.0
Arg
2.27ArgAla: 2.27 ± 0.554
0.757ArgCys: 0.757 ± 0.386
3.405ArgAsp: 3.405 ± 1.279
3.027ArgGlu: 3.027 ± 1.543
3.405ArgPhe: 3.405 ± 0.53
3.027ArgGly: 3.027 ± 1.472
0.757ArgHis: 0.757 ± 0.217
3.784ArgIle: 3.784 ± 0.723
2.649ArgLys: 2.649 ± 0.459
4.54ArgLeu: 4.54 ± 0.097
0.0ArgMet: 0.0 ± 0.0
2.649ArgAsn: 2.649 ± 0.144
2.27ArgPro: 2.27 ± 2.46
0.757ArgGln: 0.757 ± 0.217
3.405ArgArg: 3.405 ± 0.53
4.919ArgSer: 4.919 ± 0.096
3.405ArgThr: 3.405 ± 0.53
3.405ArgVal: 3.405 ± 0.073
0.757ArgTrp: 0.757 ± 0.217
2.27ArgTyr: 2.27 ± 0.651
0.0ArgXaa: 0.0 ± 0.0
Ser
6.054SerAla: 6.054 ± 1.134
0.757SerCys: 0.757 ± 0.386
5.297SerAsp: 5.297 ± 0.917
4.54SerGlu: 4.54 ± 0.097
2.27SerPhe: 2.27 ± 0.049
4.162SerGly: 4.162 ± 1.496
1.135SerHis: 1.135 ± 0.024
4.54SerIle: 4.54 ± 1.303
3.027SerLys: 3.027 ± 1.543
5.675SerLeu: 5.675 ± 0.724
1.892SerMet: 1.892 ± 0.241
4.54SerAsn: 4.54 ± 2.509
4.54SerPro: 4.54 ± 0.7
2.27SerGln: 2.27 ± 0.651
3.784SerArg: 3.784 ± 0.483
7.946SerSer: 7.946 ± 1.979
6.432SerThr: 6.432 ± 2.147
4.919SerVal: 4.919 ± 0.699
1.135SerTrp: 1.135 ± 0.024
2.27SerTyr: 2.27 ± 0.651
0.0SerXaa: 0.0 ± 0.0
Thr
1.513ThrAla: 1.513 ± 0.434
0.757ThrCys: 0.757 ± 0.386
1.513ThrAsp: 1.513 ± 0.434
3.027ThrGlu: 3.027 ± 0.337
2.27ThrPhe: 2.27 ± 0.651
2.649ThrGly: 2.649 ± 0.459
1.135ThrHis: 1.135 ± 0.024
2.27ThrIle: 2.27 ± 1.254
2.649ThrLys: 2.649 ± 0.144
3.405ThrLeu: 3.405 ± 1.133
1.135ThrMet: 1.135 ± 0.024
3.027ThrAsn: 3.027 ± 0.869
4.162ThrPro: 4.162 ± 2.702
1.892ThrGln: 1.892 ± 0.844
3.784ThrArg: 3.784 ± 0.483
4.162ThrSer: 4.162 ± 0.893
4.54ThrThr: 4.54 ± 1.906
4.919ThrVal: 4.919 ± 1.11
0.378ThrTrp: 0.378 ± 0.41
1.135ThrTyr: 1.135 ± 0.579
0.0ThrXaa: 0.0 ± 0.0
Val
5.297ValAla: 5.297 ± 0.917
0.378ValCys: 0.378 ± 0.193
4.919ValAsp: 4.919 ± 0.096
4.54ValGlu: 4.54 ± 0.506
2.649ValPhe: 2.649 ± 0.747
4.919ValGly: 4.919 ± 1.904
1.892ValHis: 1.892 ± 0.361
5.297ValIle: 5.297 ± 0.891
4.919ValLys: 4.919 ± 1.904
5.675ValLeu: 5.675 ± 1.327
1.513ValMet: 1.513 ± 1.037
3.405ValAsn: 3.405 ± 0.53
2.649ValPro: 2.649 ± 1.061
0.757ValGln: 0.757 ± 0.386
4.162ValArg: 4.162 ± 0.29
3.784ValSer: 3.784 ± 0.483
3.405ValThr: 3.405 ± 1.279
7.567ValVal: 7.567 ± 0.843
0.378ValTrp: 0.378 ± 0.193
3.027ValTyr: 3.027 ± 0.337
0.0ValXaa: 0.0 ± 0.0
Trp
0.757TrpAla: 0.757 ± 0.217
0.0TrpCys: 0.0 ± 0.0
0.378TrpAsp: 0.378 ± 0.193
0.757TrpGlu: 0.757 ± 0.217
0.757TrpPhe: 0.757 ± 0.217
1.513TrpGly: 1.513 ± 0.434
0.757TrpHis: 0.757 ± 0.386
0.757TrpIle: 0.757 ± 0.82
0.0TrpLys: 0.0 ± 0.0
1.513TrpLeu: 1.513 ± 0.434
0.378TrpMet: 0.378 ± 0.193
0.378TrpAsn: 0.378 ± 0.41
0.378TrpPro: 0.378 ± 0.41
0.757TrpGln: 0.757 ± 0.217
1.513TrpArg: 1.513 ± 1.037
0.0TrpSer: 0.0 ± 0.0
0.757TrpThr: 0.757 ± 0.217
1.135TrpVal: 1.135 ± 0.024
0.0TrpTrp: 0.0 ± 0.0
0.378TrpTyr: 0.378 ± 0.41
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.892TyrAla: 1.892 ± 0.241
1.513TyrCys: 1.513 ± 0.434
1.892TyrAsp: 1.892 ± 0.361
2.649TyrGlu: 2.649 ± 1.35
1.135TyrPhe: 1.135 ± 0.627
0.757TyrGly: 0.757 ± 0.386
1.892TyrHis: 1.892 ± 0.361
2.27TyrIle: 2.27 ± 0.554
1.513TyrLys: 1.513 ± 0.434
3.027TyrLeu: 3.027 ± 0.337
0.757TyrMet: 0.757 ± 0.386
0.757TyrAsn: 0.757 ± 0.386
0.378TyrPro: 0.378 ± 0.41
3.027TyrGln: 3.027 ± 0.266
1.135TyrArg: 1.135 ± 0.024
3.027TyrSer: 3.027 ± 0.266
0.757TyrThr: 0.757 ± 0.217
1.135TyrVal: 1.135 ± 0.024
1.135TyrTrp: 1.135 ± 0.627
2.27TyrTyr: 2.27 ± 0.554
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2644 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski