Capuchin monkey hepatitis B virus

Taxonomy: Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes; Blubervirales; Hepadnaviridae; Orthohepadnavirus

Average proteome isoelectric point is 8.15

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 6 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A2R4KZU8|A0A2R4KZU8_9HEPA Protein X OS=Capuchin monkey hepatitis B virus OX=2163996 GN=X PE=3 SV=1
MM1 pKa = 7.71GLNQSTINPLGFFPSHH17 pKa = 6.03QLDD20 pKa = 3.75PLFKK24 pKa = 10.35ANSPAADD31 pKa = 3.47WDD33 pKa = 4.12QNPHH37 pKa = 6.38KK38 pKa = 10.57DD39 pKa = 3.48PWPSAHH45 pKa = 6.29EE46 pKa = 4.3VPVGAFGPGLVPPHH60 pKa = 6.62GGLLGWNPQSQGQVTLLPKK79 pKa = 10.49DD80 pKa = 4.01PPAQLPNRR88 pKa = 11.84NSARR92 pKa = 11.84VPTPITPPLRR102 pKa = 11.84DD103 pKa = 3.51THH105 pKa = 5.95PQAMTWNISNFQKK118 pKa = 10.81ALQDD122 pKa = 3.33PRR124 pKa = 11.84VRR126 pKa = 11.84GLYY129 pKa = 9.96FPAGGSSSGIPTPAPTTASTISSLFATTGDD159 pKa = 3.18PVEE162 pKa = 4.21NMEE165 pKa = 4.96NITSGFLGPLLALQAVFFLLTKK187 pKa = 10.24ILTIPQSLDD196 pKa = 3.56SLWTSLNFLGEE207 pKa = 4.28TPACPGRR214 pKa = 11.84NLQSPTCSHH223 pKa = 6.69SPTSCPQTCPGYY235 pKa = 10.61RR236 pKa = 11.84WMCLRR241 pKa = 11.84RR242 pKa = 11.84FIIFLFIPLLCLIFLLVLLDD262 pKa = 3.96YY263 pKa = 11.31QGMLPVCPLLPGTTTTTTTGPCKK286 pKa = 9.66TCTPIAPGSSMYY298 pKa = 10.25PSCCCTKK305 pKa = 9.49PTDD308 pKa = 4.27GNCTCIPIPSSWAFARR324 pKa = 11.84FLWDD328 pKa = 2.94WASVRR333 pKa = 11.84FSWLSLLAPFVQWFVGLSPTAWLLVIWMIWFWGPSLYY370 pKa = 10.49TILSPFFPLLPVFFCLWVYY389 pKa = 10.5II390 pKa = 4.23

Molecular weight: 42.82 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A2R4QN08|A0A2R4QN08_9HEPA Middle surface antigen OS=Capuchin monkey hepatitis B virus OX=2163996 PE=4 SV=1
MM1 pKa = 7.8PLSCQLFRR9 pKa = 11.84KK10 pKa = 9.82LLLLEE15 pKa = 4.89GDD17 pKa = 3.51QGPLEE22 pKa = 4.34EE23 pKa = 4.74EE24 pKa = 4.39LPRR27 pKa = 11.84LADD30 pKa = 3.38EE31 pKa = 4.61DD32 pKa = 4.03LNRR35 pKa = 11.84RR36 pKa = 11.84VAEE39 pKa = 4.31DD40 pKa = 4.58LNLQLPPVSIPWTHH54 pKa = 5.68TVGEE58 pKa = 4.34FTGLYY63 pKa = 9.97SVTPLRR69 pKa = 11.84YY70 pKa = 9.03NPEE73 pKa = 3.45WKK75 pKa = 10.09IPEE78 pKa = 4.28FPNIHH83 pKa = 6.73LKK85 pKa = 10.04QDD87 pKa = 3.38IIKK90 pKa = 10.32RR91 pKa = 11.84CTDD94 pKa = 3.64FVGPLNANEE103 pKa = 3.9TRR105 pKa = 11.84RR106 pKa = 11.84LKK108 pKa = 10.86LVLPARR114 pKa = 11.84FYY116 pKa = 11.11PKK118 pKa = 8.17VTKK121 pKa = 10.3YY122 pKa = 10.46FPLEE126 pKa = 4.06KK127 pKa = 9.93GIKK130 pKa = 8.49PHH132 pKa = 7.02YY133 pKa = 8.48PDD135 pKa = 3.51QVVNHH140 pKa = 5.4YY141 pKa = 10.63FKK143 pKa = 10.87VQEE146 pKa = 4.11YY147 pKa = 10.52LHH149 pKa = 6.05TLWKK153 pKa = 10.61SGILYY158 pKa = 10.13KK159 pKa = 10.5RR160 pKa = 11.84EE161 pKa = 4.21TTHH164 pKa = 6.06SASFFGSPYY173 pKa = 8.4TWEE176 pKa = 4.26HH177 pKa = 5.18QLQHH181 pKa = 5.04GTKK184 pKa = 9.22PVYY187 pKa = 9.64HH188 pKa = 6.34QSSGVLPQSSARR200 pKa = 11.84PLVQSEE206 pKa = 4.54FTSSRR211 pKa = 11.84LGSKK215 pKa = 10.16SSQRR219 pKa = 11.84PLAFSSRR226 pKa = 11.84SACRR230 pKa = 11.84GLWTRR235 pKa = 11.84PSSSSRR241 pKa = 11.84RR242 pKa = 11.84FARR245 pKa = 11.84LEE247 pKa = 3.91SSVTGSSHH255 pKa = 6.62PVAKK259 pKa = 10.38RR260 pKa = 11.84SACSTAQSQLSQSTHH275 pKa = 4.23SHH277 pKa = 4.56NTTTKK282 pKa = 8.24GHH284 pKa = 6.52SSPSHH289 pKa = 5.72DD290 pKa = 4.55LEE292 pKa = 4.07YY293 pKa = 11.15LKK295 pKa = 10.91LSEE298 pKa = 4.33GSSRR302 pKa = 11.84SSSQGAVFPCWWLQFRR318 pKa = 11.84DD319 pKa = 4.08SNPCSDD325 pKa = 3.96YY326 pKa = 10.79CLHH329 pKa = 6.93HH330 pKa = 6.62IVSLRR335 pKa = 11.84DD336 pKa = 3.06NWGPCGEE343 pKa = 4.61HH344 pKa = 6.65GEE346 pKa = 4.06HH347 pKa = 7.36HH348 pKa = 6.08IRR350 pKa = 11.84IPRR353 pKa = 11.84TPARR357 pKa = 11.84ITGGVFLVDD366 pKa = 4.0KK367 pKa = 10.39NPHH370 pKa = 5.83NSSEE374 pKa = 4.07SRR376 pKa = 11.84LVVDD380 pKa = 5.53FSQFSRR386 pKa = 11.84GDD388 pKa = 3.55TRR390 pKa = 11.84VSWPKK395 pKa = 9.99FAVPNLQSLTNLLSSDD411 pKa = 4.31LSWLSLDD418 pKa = 3.48VSAAFYY424 pKa = 10.35HH425 pKa = 6.61LPLHH429 pKa = 6.16PAVMPHH435 pKa = 6.65LLVGTAGLSRR445 pKa = 11.84YY446 pKa = 7.18VARR449 pKa = 11.84LSSPARR455 pKa = 11.84NNNHH459 pKa = 5.34HH460 pKa = 6.31HH461 pKa = 6.49HH462 pKa = 6.52RR463 pKa = 11.84TLQDD467 pKa = 2.99LHH469 pKa = 6.29AHH471 pKa = 5.84CTRR474 pKa = 11.84EE475 pKa = 4.18LYY477 pKa = 10.68VSLMLLYY484 pKa = 8.84QTYY487 pKa = 9.1GWKK490 pKa = 10.04LHH492 pKa = 6.48LYY494 pKa = 8.45SHH496 pKa = 7.36PIVLGFRR503 pKa = 11.84KK504 pKa = 9.99VPMGLGLSPFLLAQFTSAICSVVRR528 pKa = 11.84RR529 pKa = 11.84AFPHH533 pKa = 6.38CMAFSYY539 pKa = 10.53MDD541 pKa = 4.5DD542 pKa = 3.65LVLGAKK548 pKa = 9.36SVHH551 pKa = 6.13HH552 pKa = 6.53LEE554 pKa = 4.43SLFSAITSFLLSLGIHH570 pKa = 6.68LNPEE574 pKa = 3.65KK575 pKa = 10.04TKK577 pKa = 10.52RR578 pKa = 11.84WGKK581 pKa = 9.39SLQFMGYY588 pKa = 10.21VIGAWGSLPQDD599 pKa = 4.11HH600 pKa = 6.82IRR602 pKa = 11.84AKK604 pKa = 9.95IQRR607 pKa = 11.84CFRR610 pKa = 11.84TLPCNRR616 pKa = 11.84PIDD619 pKa = 3.55WKK621 pKa = 8.96VCQRR625 pKa = 11.84IVGLLGFAAPFTQCGYY641 pKa = 8.88PALMPIYY648 pKa = 10.04HH649 pKa = 7.4AIKK652 pKa = 10.19LKK654 pKa = 10.31QAFSFSLTYY663 pKa = 10.44KK664 pKa = 10.77AFLRR668 pKa = 11.84DD669 pKa = 3.4QYY671 pKa = 11.04LTLHH675 pKa = 6.18PVARR679 pKa = 11.84QRR681 pKa = 11.84PGPCQVFADD690 pKa = 4.34ATPTGWGLVCGQQRR704 pKa = 11.84MRR706 pKa = 11.84GDD708 pKa = 3.89FVSPLPIHH716 pKa = 5.41TAEE719 pKa = 4.49LLAACFARR727 pKa = 11.84CWTGAKK733 pKa = 9.96HH734 pKa = 6.11IATDD738 pKa = 3.49NSVVLSRR745 pKa = 11.84KK746 pKa = 7.43YY747 pKa = 9.41TSFPWLLGCAANWILRR763 pKa = 11.84GTCFVYY769 pKa = 10.73VPSQQNPADD778 pKa = 4.03DD779 pKa = 4.24PSRR782 pKa = 11.84GRR784 pKa = 11.84LGLLRR789 pKa = 11.84PLPRR793 pKa = 11.84LHH795 pKa = 6.93FLPSTGRR802 pKa = 11.84TSLYY806 pKa = 10.51ADD808 pKa = 3.69SPPVPFHH815 pKa = 6.63RR816 pKa = 11.84PARR819 pKa = 11.84VHH821 pKa = 6.17FASPLHH827 pKa = 6.31DD828 pKa = 3.21AWRR831 pKa = 11.84PPP833 pKa = 3.23

Molecular weight: 94.05 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

6

0

6

2097

153

833

349.5

39.05

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.056 ± 0.665

3.958 ± 0.754

2.957 ± 0.324

2.48 ± 0.54

5.818 ± 0.576

5.866 ± 0.235

2.909 ± 1.158

3.958 ± 0.692

2.48 ± 0.644

13.114 ± 0.607

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.621 ± 0.261

2.575 ± 0.229

9.68 ± 0.977

3.624 ± 0.341

5.675 ± 1.08

9.537 ± 0.443

7.058 ± 1.059

5.007 ± 0.404

3.195 ± 0.592

2.432 ± 0.393
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski