Amino acid dipepetide frequency for Abyssicoccus albus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.46AlaAla: 3.46 ± 0.11
0.507AlaCys: 0.507 ± 0.032
2.482AlaAsp: 2.482 ± 0.082
3.303AlaGlu: 3.303 ± 0.098
2.584AlaPhe: 2.584 ± 0.086
3.686AlaGly: 3.686 ± 0.106
1.391AlaHis: 1.391 ± 0.052
5.51AlaIle: 5.51 ± 0.128
4.281AlaLys: 4.281 ± 0.105
6.323AlaLeu: 6.323 ± 0.127
1.96AlaMet: 1.96 ± 0.068
2.478AlaAsn: 2.478 ± 0.067
1.604AlaPro: 1.604 ± 0.063
2.17AlaGln: 2.17 ± 0.07
2.18AlaArg: 2.18 ± 0.076
3.428AlaSer: 3.428 ± 0.086
3.255AlaThr: 3.255 ± 0.098
3.799AlaVal: 3.799 ± 0.101
0.398AlaTrp: 0.398 ± 0.027
2.069AlaTyr: 2.069 ± 0.063
0.0AlaXaa: 0.0 ± 0.0
Cys
0.385CysAla: 0.385 ± 0.029
0.084CysCys: 0.084 ± 0.015
0.375CysAsp: 0.375 ± 0.029
0.4CysGlu: 0.4 ± 0.029
0.23CysPhe: 0.23 ± 0.023
0.526CysGly: 0.526 ± 0.035
0.226CysHis: 0.226 ± 0.02
0.616CysIle: 0.616 ± 0.034
0.364CysLys: 0.364 ± 0.03
0.511CysLeu: 0.511 ± 0.035
0.176CysMet: 0.176 ± 0.017
0.341CysAsn: 0.341 ± 0.024
0.281CysPro: 0.281 ± 0.025
0.205CysGln: 0.205 ± 0.02
0.233CysArg: 0.233 ± 0.021
0.467CysSer: 0.467 ± 0.035
0.383CysThr: 0.383 ± 0.027
0.442CysVal: 0.442 ± 0.028
0.05CysTrp: 0.05 ± 0.01
0.266CysTyr: 0.266 ± 0.024
0.0CysXaa: 0.0 ± 0.0
Asp
3.397AspAla: 3.397 ± 0.086
0.366AspCys: 0.366 ± 0.031
4.036AspAsp: 4.036 ± 0.103
6.134AspGlu: 6.134 ± 0.145
2.488AspPhe: 2.488 ± 0.075
3.803AspGly: 3.803 ± 0.18
1.65AspHis: 1.65 ± 0.058
5.548AspIle: 5.548 ± 0.118
4.082AspLys: 4.082 ± 0.111
4.938AspLeu: 4.938 ± 0.099
1.556AspMet: 1.556 ± 0.05
2.681AspAsn: 2.681 ± 0.087
1.671AspPro: 1.671 ± 0.086
2.689AspGln: 2.689 ± 0.069
2.404AspArg: 2.404 ± 0.073
3.527AspSer: 3.527 ± 0.36
2.809AspThr: 2.809 ± 0.084
4.612AspVal: 4.612 ± 0.165
0.455AspTrp: 0.455 ± 0.03
2.721AspTyr: 2.721 ± 0.077
0.0AspXaa: 0.0 ± 0.0
Glu
4.654GluAla: 4.654 ± 0.102
0.406GluCys: 0.406 ± 0.03
4.427GluAsp: 4.427 ± 0.126
6.277GluGlu: 6.277 ± 0.18
2.633GluPhe: 2.633 ± 0.066
3.965GluGly: 3.965 ± 0.096
2.121GluHis: 2.121 ± 0.062
5.697GluIle: 5.697 ± 0.121
4.804GluLys: 4.804 ± 0.104
7.066GluLeu: 7.066 ± 0.121
2.53GluMet: 2.53 ± 0.071
3.186GluAsn: 3.186 ± 0.083
2.132GluPro: 2.132 ± 0.28
4.17GluGln: 4.17 ± 0.1
3.498GluArg: 3.498 ± 0.095
4.398GluSer: 4.398 ± 0.105
3.586GluThr: 3.586 ± 0.095
5.598GluVal: 5.598 ± 0.131
0.599GluTrp: 0.599 ± 0.036
3.016GluTyr: 3.016 ± 0.08
0.0GluXaa: 0.0 ± 0.0
Phe
2.26PheAla: 2.26 ± 0.075
0.245PheCys: 0.245 ± 0.025
3.062PheAsp: 3.062 ± 0.084
3.141PheGlu: 3.141 ± 0.087
1.939PhePhe: 1.939 ± 0.075
3.098PheGly: 3.098 ± 0.091
0.854PheHis: 0.854 ± 0.044
4.901PheIle: 4.901 ± 0.115
3.162PheLys: 3.162 ± 0.081
3.424PheLeu: 3.424 ± 0.094
1.278PheMet: 1.278 ± 0.057
2.953PheAsn: 2.953 ± 0.085
1.102PhePro: 1.102 ± 0.048
1.127PheGln: 1.127 ± 0.046
1.177PheArg: 1.177 ± 0.05
2.547PheSer: 2.547 ± 0.075
2.442PheThr: 2.442 ± 0.071
2.974PheVal: 2.974 ± 0.084
0.306PheTrp: 0.306 ± 0.029
1.629PheTyr: 1.629 ± 0.064
0.0PheXaa: 0.0 ± 0.0
Gly
3.9GlyAla: 3.9 ± 0.113
0.498GlyCys: 0.498 ± 0.03
3.265GlyAsp: 3.265 ± 0.101
4.111GlyGlu: 4.111 ± 0.099
2.898GlyPhe: 2.898 ± 0.072
3.948GlyGly: 3.948 ± 0.108
1.51GlyHis: 1.51 ± 0.047
5.395GlyIle: 5.395 ± 0.137
3.763GlyLys: 3.763 ± 0.103
5.711GlyLeu: 5.711 ± 0.122
1.839GlyMet: 1.839 ± 0.052
2.145GlyAsn: 2.145 ± 0.062
1.541GlyPro: 1.541 ± 0.059
2.383GlyGln: 2.383 ± 0.072
2.203GlyArg: 2.203 ± 0.078
3.391GlySer: 3.391 ± 0.083
3.422GlyThr: 3.422 ± 0.104
4.589GlyVal: 4.589 ± 0.101
0.431GlyTrp: 0.431 ± 0.03
2.857GlyTyr: 2.857 ± 0.082
0.002GlyXaa: 0.002 ± 0.002
His
1.296HisAla: 1.296 ± 0.053
0.216HisCys: 0.216 ± 0.022
1.719HisAsp: 1.719 ± 0.062
1.61HisGlu: 1.61 ± 0.057
1.166HisPhe: 1.166 ± 0.052
1.433HisGly: 1.433 ± 0.053
0.984HisHis: 0.984 ± 0.049
2.306HisIle: 2.306 ± 0.068
1.355HisLys: 1.355 ± 0.059
2.184HisLeu: 2.184 ± 0.082
0.662HisMet: 0.662 ± 0.036
1.236HisAsn: 1.236 ± 0.062
1.062HisPro: 1.062 ± 0.052
1.097HisGln: 1.097 ± 0.052
1.032HisArg: 1.032 ± 0.039
1.372HisSer: 1.372 ± 0.059
1.215HisThr: 1.215 ± 0.062
1.516HisVal: 1.516 ± 0.061
0.189HisTrp: 0.189 ± 0.02
1.188HisTyr: 1.188 ± 0.049
0.0HisXaa: 0.0 ± 0.0
Ile
5.629IleAla: 5.629 ± 0.125
0.712IleCys: 0.712 ± 0.043
6.474IleAsp: 6.474 ± 0.118
7.542IleGlu: 7.542 ± 0.193
3.451IlePhe: 3.451 ± 0.101
5.933IleGly: 5.933 ± 0.13
2.26IleHis: 2.26 ± 0.071
7.86IleIle: 7.86 ± 0.186
6.09IleLys: 6.09 ± 0.116
7.169IleLeu: 7.169 ± 0.152
2.197IleMet: 2.197 ± 0.065
4.727IleAsn: 4.727 ± 0.106
3.045IlePro: 3.045 ± 0.083
3.537IleGln: 3.537 ± 0.082
2.79IleArg: 2.79 ± 0.081
5.177IleSer: 5.177 ± 0.1
4.637IleThr: 4.637 ± 0.098
6.231IleVal: 6.231 ± 0.13
0.521IleTrp: 0.521 ± 0.037
3.129IleTyr: 3.129 ± 0.085
0.0IleXaa: 0.0 ± 0.0
Lys
4.316LysAla: 4.316 ± 0.105
0.329LysCys: 0.329 ± 0.027
4.829LysAsp: 4.829 ± 0.107
6.486LysGlu: 6.486 ± 0.128
2.344LysPhe: 2.344 ± 0.058
3.862LysGly: 3.862 ± 0.095
1.768LysHis: 1.768 ± 0.068
4.769LysIle: 4.769 ± 0.101
5.466LysLys: 5.466 ± 0.127
5.751LysLeu: 5.751 ± 0.103
2.17LysMet: 2.17 ± 0.073
3.213LysAsn: 3.213 ± 0.087
2.237LysPro: 2.237 ± 0.067
3.313LysGln: 3.313 ± 0.085
2.855LysArg: 2.855 ± 0.076
4.752LysSer: 4.752 ± 0.097
3.755LysThr: 3.755 ± 0.082
4.666LysVal: 4.666 ± 0.102
0.448LysTrp: 0.448 ± 0.026
2.861LysTyr: 2.861 ± 0.08
0.0LysXaa: 0.0 ± 0.0
Leu
5.005LeuAla: 5.005 ± 0.111
0.595LeuCys: 0.595 ± 0.034
5.02LeuAsp: 5.02 ± 0.103
5.653LeuGlu: 5.653 ± 0.12
4.62LeuPhe: 4.62 ± 0.132
5.414LeuGly: 5.414 ± 0.133
1.673LeuHis: 1.673 ± 0.06
8.539LeuIle: 8.539 ± 0.284
6.783LeuLys: 6.783 ± 0.13
8.825LeuLeu: 8.825 ± 0.179
2.831LeuMet: 2.831 ± 0.079
6.166LeuAsn: 6.166 ± 0.148
3.156LeuPro: 3.156 ± 0.091
2.964LeuGln: 2.964 ± 0.073
2.855LeuArg: 2.855 ± 0.077
7.068LeuSer: 7.068 ± 0.139
5.696LeuThr: 5.696 ± 0.16
5.364LeuVal: 5.364 ± 0.237
0.57LeuTrp: 0.57 ± 0.034
3.462LeuTyr: 3.462 ± 0.1
0.0LeuXaa: 0.0 ± 0.0
Met
1.694MetAla: 1.694 ± 0.059
0.168MetCys: 0.168 ± 0.017
1.721MetAsp: 1.721 ± 0.06
1.678MetGlu: 1.678 ± 0.055
1.21MetPhe: 1.21 ± 0.059
1.481MetGly: 1.481 ± 0.057
0.578MetHis: 0.578 ± 0.032
2.869MetIle: 2.869 ± 0.077
2.645MetLys: 2.645 ± 0.068
2.718MetLeu: 2.718 ± 0.071
1.093MetMet: 1.093 ± 0.06
2.348MetAsn: 2.348 ± 0.068
0.949MetPro: 0.949 ± 0.039
0.932MetGln: 0.932 ± 0.041
0.94MetArg: 0.94 ± 0.047
2.061MetSer: 2.061 ± 0.065
2.0MetThr: 2.0 ± 0.063
1.594MetVal: 1.594 ± 0.057
0.155MetTrp: 0.155 ± 0.016
1.02MetTyr: 1.02 ± 0.043
0.0MetXaa: 0.0 ± 0.0
Asn
2.963AsnAla: 2.963 ± 0.08
0.276AsnCys: 0.276 ± 0.024
3.594AsnAsp: 3.594 ± 0.097
4.645AsnGlu: 4.645 ± 0.131
1.877AsnPhe: 1.877 ± 0.069
2.986AsnGly: 2.986 ± 0.092
1.613AsnHis: 1.613 ± 0.06
4.807AsnIle: 4.807 ± 0.113
4.186AsnLys: 4.186 ± 0.107
3.808AsnLeu: 3.808 ± 0.082
1.386AsnMet: 1.386 ± 0.055
2.808AsnAsn: 2.808 ± 0.094
1.935AsnPro: 1.935 ± 0.068
2.475AsnGln: 2.475 ± 0.076
2.023AsnArg: 2.023 ± 0.064
2.454AsnSer: 2.454 ± 0.079
2.624AsnThr: 2.624 ± 0.087
3.481AsnVal: 3.481 ± 0.091
0.312AsnTrp: 0.312 ± 0.024
1.99AsnTyr: 1.99 ± 0.068
0.0AsnXaa: 0.0 ± 0.0
Pro
1.363ProAla: 1.363 ± 0.056
0.191ProCys: 0.191 ± 0.021
1.793ProAsp: 1.793 ± 0.146
2.237ProGlu: 2.237 ± 0.067
1.711ProPhe: 1.711 ± 0.06
1.698ProGly: 1.698 ± 0.068
0.748ProHis: 0.748 ± 0.036
2.898ProIle: 2.898 ± 0.084
2.18ProLys: 2.18 ± 0.073
3.196ProLeu: 3.196 ± 0.22
0.921ProMet: 0.921 ± 0.039
1.736ProAsn: 1.736 ± 0.055
0.676ProPro: 0.676 ± 0.033
0.821ProGln: 0.821 ± 0.037
0.844ProArg: 0.844 ± 0.039
2.121ProSer: 2.121 ± 0.075
2.122ProThr: 2.122 ± 0.079
2.174ProVal: 2.174 ± 0.068
0.276ProTrp: 0.276 ± 0.025
1.345ProTyr: 1.345 ± 0.048
0.0ProXaa: 0.0 ± 0.0
Gln
2.145GlnAla: 2.145 ± 0.069
0.268GlnCys: 0.268 ± 0.026
2.136GlnAsp: 2.136 ± 0.07
2.099GlnGlu: 2.099 ± 0.066
2.22GlnPhe: 2.22 ± 0.074
1.964GlnGly: 1.964 ± 0.069
1.146GlnHis: 1.146 ± 0.042
2.733GlnIle: 2.733 ± 0.083
2.572GlnLys: 2.572 ± 0.091
4.526GlnLeu: 4.526 ± 0.111
1.343GlnMet: 1.343 ± 0.054
1.941GlnAsn: 1.941 ± 0.064
0.995GlnPro: 0.995 ± 0.05
2.298GlnGln: 2.298 ± 0.091
1.535GlnArg: 1.535 ± 0.058
3.114GlnSer: 3.114 ± 0.086
2.023GlnThr: 2.023 ± 0.06
2.243GlnVal: 2.243 ± 0.062
0.383GlnTrp: 0.383 ± 0.027
2.092GlnTyr: 2.092 ± 0.059
0.0GlnXaa: 0.0 ± 0.0
Arg
2.008ArgAla: 2.008 ± 0.073
0.182ArgCys: 0.182 ± 0.02
2.071ArgAsp: 2.071 ± 0.066
2.492ArgGlu: 2.492 ± 0.075
1.657ArgPhe: 1.657 ± 0.066
1.998ArgGly: 1.998 ± 0.065
0.947ArgHis: 0.947 ± 0.043
3.026ArgIle: 3.026 ± 0.08
2.618ArgLys: 2.618 ± 0.075
3.514ArgLeu: 3.514 ± 0.089
1.131ArgMet: 1.131 ± 0.046
1.958ArgAsn: 1.958 ± 0.056
1.085ArgPro: 1.085 ± 0.054
1.579ArgGln: 1.579 ± 0.064
1.623ArgArg: 1.623 ± 0.064
1.981ArgSer: 1.981 ± 0.069
1.889ArgThr: 1.889 ± 0.068
2.484ArgVal: 2.484 ± 0.078
0.222ArgTrp: 0.222 ± 0.023
1.627ArgTyr: 1.627 ± 0.055
0.0ArgXaa: 0.0 ± 0.0
Ser
3.007SerAla: 3.007 ± 0.081
0.354SerCys: 0.354 ± 0.028
3.447SerAsp: 3.447 ± 0.097
4.346SerGlu: 4.346 ± 0.106
2.974SerPhe: 2.974 ± 0.082
3.705SerGly: 3.705 ± 0.085
1.441SerHis: 1.441 ± 0.057
5.967SerIle: 5.967 ± 0.116
4.658SerLys: 4.658 ± 0.104
6.371SerLeu: 6.371 ± 0.344
1.962SerMet: 1.962 ± 0.063
3.518SerAsn: 3.518 ± 0.099
1.692SerPro: 1.692 ± 0.064
2.138SerGln: 2.138 ± 0.063
2.17SerArg: 2.17 ± 0.065
3.789SerSer: 3.789 ± 0.11
3.665SerThr: 3.665 ± 0.109
3.872SerVal: 3.872 ± 0.085
0.411SerTrp: 0.411 ± 0.029
2.398SerTyr: 2.398 ± 0.062
0.0SerXaa: 0.0 ± 0.0
Thr
2.986ThrAla: 2.986 ± 0.094
0.325ThrCys: 0.325 ± 0.024
3.087ThrAsp: 3.087 ± 0.083
4.025ThrGlu: 4.025 ± 0.143
2.536ThrPhe: 2.536 ± 0.079
3.418ThrGly: 3.418 ± 0.089
1.401ThrHis: 1.401 ± 0.053
5.119ThrIle: 5.119 ± 0.104
3.454ThrLys: 3.454 ± 0.07
5.638ThrLeu: 5.638 ± 0.122
1.56ThrMet: 1.56 ± 0.058
2.676ThrAsn: 2.676 ± 0.091
2.216ThrPro: 2.216 ± 0.069
1.753ThrGln: 1.753 ± 0.057
1.743ThrArg: 1.743 ± 0.054
3.389ThrSer: 3.389 ± 0.085
3.42ThrThr: 3.42 ± 0.148
4.002ThrVal: 4.002 ± 0.109
0.352ThrTrp: 0.352 ± 0.028
2.098ThrTyr: 2.098 ± 0.064
0.0ThrXaa: 0.0 ± 0.0
Val
3.879ValAla: 3.879 ± 0.108
0.505ValCys: 0.505 ± 0.03
4.869ValAsp: 4.869 ± 0.348
5.085ValGlu: 5.085 ± 0.114
2.827ValPhe: 2.827 ± 0.09
4.224ValGly: 4.224 ± 0.094
1.365ValHis: 1.365 ± 0.055
6.17ValIle: 6.17 ± 0.114
4.578ValLys: 4.578 ± 0.096
6.195ValLeu: 6.195 ± 0.111
1.939ValMet: 1.939 ± 0.067
3.506ValAsn: 3.506 ± 0.087
2.165ValPro: 2.165 ± 0.077
2.32ValGln: 2.32 ± 0.065
2.249ValArg: 2.249 ± 0.065
4.017ValSer: 4.017 ± 0.095
3.904ValThr: 3.904 ± 0.093
4.641ValVal: 4.641 ± 0.104
0.465ValTrp: 0.465 ± 0.03
2.304ValTyr: 2.304 ± 0.065
0.002ValXaa: 0.002 ± 0.002
Trp
0.371TrpAla: 0.371 ± 0.032
0.071TrpCys: 0.071 ± 0.012
0.3TrpAsp: 0.3 ± 0.021
0.331TrpGlu: 0.331 ± 0.024
0.419TrpPhe: 0.419 ± 0.028
0.383TrpGly: 0.383 ± 0.032
0.142TrpHis: 0.142 ± 0.019
0.706TrpIle: 0.706 ± 0.041
0.381TrpLys: 0.381 ± 0.03
0.878TrpLeu: 0.878 ± 0.042
0.287TrpMet: 0.287 ± 0.027
0.367TrpAsn: 0.367 ± 0.026
0.195TrpPro: 0.195 ± 0.019
0.247TrpGln: 0.247 ± 0.02
0.216TrpArg: 0.216 ± 0.02
0.455TrpSer: 0.455 ± 0.033
0.352TrpThr: 0.352 ± 0.028
0.446TrpVal: 0.446 ± 0.03
0.08TrpTrp: 0.08 ± 0.012
0.272TrpTyr: 0.272 ± 0.024
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.153TyrAla: 2.153 ± 0.059
0.262TyrCys: 0.262 ± 0.027
2.861TyrAsp: 2.861 ± 0.076
3.169TyrGlu: 3.169 ± 0.088
1.839TyrPhe: 1.839 ± 0.075
2.276TyrGly: 2.276 ± 0.055
1.02TyrHis: 1.02 ± 0.043
3.673TyrIle: 3.673 ± 0.09
2.771TyrLys: 2.771 ± 0.089
3.512TyrLeu: 3.512 ± 0.094
1.032TyrMet: 1.032 ± 0.052
2.258TyrAsn: 2.258 ± 0.072
1.311TyrPro: 1.311 ± 0.046
1.56TyrGln: 1.56 ± 0.055
1.52TyrArg: 1.52 ± 0.064
2.377TyrSer: 2.377 ± 0.07
1.998TyrThr: 1.998 ± 0.059
2.476TyrVal: 2.476 ± 0.076
0.278TyrTrp: 0.278 ± 0.023
1.858TyrTyr: 1.858 ± 0.065
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.002XaaLeu: 0.002 ± 0.002
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.002XaaVal: 0.002 ± 0.002
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.006XaaXaa: 0.006 ± 0.004
Statistics based on 1737 proteins (522518 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski