Amino acid dipepetide frequency for Chlamydia phage 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.509AlaAla: 3.509 ± 2.167
0.0AlaCys: 0.0 ± 0.0
2.105AlaAsp: 2.105 ± 0.855
3.509AlaGlu: 3.509 ± 1.334
4.912AlaPhe: 4.912 ± 2.145
4.912AlaGly: 4.912 ± 1.999
0.702AlaHis: 0.702 ± 1.053
2.807AlaIle: 2.807 ± 1.552
4.211AlaLys: 4.211 ± 2.741
4.912AlaLeu: 4.912 ± 2.165
2.105AlaMet: 2.105 ± 1.778
1.404AlaAsn: 1.404 ± 1.454
2.105AlaPro: 2.105 ± 1.111
4.912AlaGln: 4.912 ± 1.745
7.018AlaArg: 7.018 ± 1.949
4.211AlaSer: 4.211 ± 2.555
5.614AlaThr: 5.614 ± 1.643
3.509AlaVal: 3.509 ± 1.582
0.702AlaTrp: 0.702 ± 0.457
4.211AlaTyr: 4.211 ± 0.909
0.0AlaXaa: 0.0 ± 0.0
Cys
2.807CysAla: 2.807 ± 1.174
0.0CysCys: 0.0 ± 0.0
2.105CysAsp: 2.105 ± 1.302
0.702CysGlu: 0.702 ± 1.281
1.404CysPhe: 1.404 ± 1.284
2.105CysGly: 2.105 ± 0.855
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.404CysLeu: 1.404 ± 0.602
2.105CysMet: 2.105 ± 1.355
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.702CysGln: 0.702 ± 0.457
1.404CysArg: 1.404 ± 1.284
0.702CysSer: 0.702 ± 0.642
0.702CysThr: 0.702 ± 1.281
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.404AspAla: 1.404 ± 0.913
1.404AspCys: 1.404 ± 1.454
2.105AspAsp: 2.105 ± 1.288
3.509AspGlu: 3.509 ± 1.829
3.509AspPhe: 3.509 ± 1.095
1.404AspGly: 1.404 ± 0.897
2.105AspHis: 2.105 ± 1.158
2.105AspIle: 2.105 ± 1.698
4.211AspLys: 4.211 ± 3.213
2.807AspLeu: 2.807 ± 1.379
1.404AspMet: 1.404 ± 1.266
2.105AspAsn: 2.105 ± 0.855
2.807AspPro: 2.807 ± 1.984
1.404AspGln: 1.404 ± 1.231
4.211AspArg: 4.211 ± 1.17
5.614AspSer: 5.614 ± 1.394
2.105AspThr: 2.105 ± 1.37
1.404AspVal: 1.404 ± 1.126
0.702AspTrp: 0.702 ± 0.642
3.509AspTyr: 3.509 ± 1.23
0.0AspXaa: 0.0 ± 0.0
Glu
6.316GluAla: 6.316 ± 4.04
0.702GluCys: 0.702 ± 0.89
3.509GluAsp: 3.509 ± 2.223
5.614GluGlu: 5.614 ± 3.059
2.105GluPhe: 2.105 ± 0.855
2.105GluGly: 2.105 ± 0.906
2.105GluHis: 2.105 ± 0.834
4.211GluIle: 4.211 ± 1.957
2.807GluLys: 2.807 ± 1.926
2.807GluLeu: 2.807 ± 1.188
1.404GluMet: 1.404 ± 0.975
4.211GluAsn: 4.211 ± 1.569
2.105GluPro: 2.105 ± 1.111
5.614GluGln: 5.614 ± 1.888
4.912GluArg: 4.912 ± 2.507
2.807GluSer: 2.807 ± 1.324
0.0GluThr: 0.0 ± 0.0
2.807GluVal: 2.807 ± 1.231
0.0GluTrp: 0.0 ± 0.0
4.211GluTyr: 4.211 ± 1.235
0.0GluXaa: 0.0 ± 0.0
Phe
2.105PheAla: 2.105 ± 1.185
2.105PheCys: 2.105 ± 0.855
2.807PheAsp: 2.807 ± 1.138
1.404PheGlu: 1.404 ± 0.897
2.105PhePhe: 2.105 ± 0.974
2.807PheGly: 2.807 ± 1.187
0.0PheHis: 0.0 ± 0.0
2.807PheIle: 2.807 ± 1.023
2.807PheLys: 2.807 ± 1.424
5.614PheLeu: 5.614 ± 1.338
2.105PheMet: 2.105 ± 1.405
2.105PheAsn: 2.105 ± 0.855
2.105PhePro: 2.105 ± 1.158
2.105PheGln: 2.105 ± 0.906
2.807PheArg: 2.807 ± 2.409
5.614PheSer: 5.614 ± 2.324
4.211PheThr: 4.211 ± 1.842
3.509PheVal: 3.509 ± 1.151
1.404PheTrp: 1.404 ± 1.191
0.702PheTyr: 0.702 ± 0.457
0.0PheXaa: 0.0 ± 0.0
Gly
5.614GlyAla: 5.614 ± 1.952
0.702GlyCys: 0.702 ± 0.642
2.105GlyAsp: 2.105 ± 0.855
2.807GlyGlu: 2.807 ± 1.231
2.807GlyPhe: 2.807 ± 0.931
4.912GlyGly: 4.912 ± 2.238
0.0GlyHis: 0.0 ± 0.0
2.807GlyIle: 2.807 ± 1.266
4.211GlyLys: 4.211 ± 2.082
7.719GlyLeu: 7.719 ± 2.718
0.0GlyMet: 0.0 ± 0.0
3.509GlyAsn: 3.509 ± 1.207
2.105GlyPro: 2.105 ± 1.111
0.702GlyGln: 0.702 ± 0.642
0.702GlyArg: 0.702 ± 0.816
5.614GlySer: 5.614 ± 1.377
3.509GlyThr: 3.509 ± 2.15
5.614GlyVal: 5.614 ± 1.888
0.702GlyTrp: 0.702 ± 0.457
3.509GlyTyr: 3.509 ± 1.334
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.702HisAsp: 0.702 ± 0.457
0.702HisGlu: 0.702 ± 0.642
2.105HisPhe: 2.105 ± 1.37
0.702HisGly: 0.702 ± 0.457
0.0HisHis: 0.0 ± 0.0
0.702HisIle: 0.702 ± 0.642
1.404HisLys: 1.404 ± 1.126
2.807HisLeu: 2.807 ± 1.204
0.0HisMet: 0.0 ± 0.0
0.702HisAsn: 0.702 ± 0.89
2.105HisPro: 2.105 ± 1.67
0.0HisGln: 0.0 ± 0.0
0.702HisArg: 0.702 ± 0.457
1.404HisSer: 1.404 ± 0.602
0.0HisThr: 0.0 ± 0.0
1.404HisVal: 1.404 ± 0.897
0.0HisTrp: 0.0 ± 0.0
1.404HisTyr: 1.404 ± 1.284
0.0HisXaa: 0.0 ± 0.0
Ile
2.807IleAla: 2.807 ± 1.866
0.0IleCys: 0.0 ± 0.0
1.404IleAsp: 1.404 ± 0.602
2.807IleGlu: 2.807 ± 1.443
2.105IlePhe: 2.105 ± 0.855
2.807IleGly: 2.807 ± 1.023
0.702IleHis: 0.702 ± 0.457
1.404IleIle: 1.404 ± 1.191
1.404IleLys: 1.404 ± 1.126
2.105IleLeu: 2.105 ± 1.794
0.702IleMet: 0.702 ± 1.265
1.404IleAsn: 1.404 ± 0.897
2.105IlePro: 2.105 ± 1.185
1.404IleGln: 1.404 ± 0.913
6.316IleArg: 6.316 ± 2.991
2.105IleSer: 2.105 ± 1.363
0.702IleThr: 0.702 ± 0.457
1.404IleVal: 1.404 ± 0.897
2.105IleTrp: 2.105 ± 0.855
4.211IleTyr: 4.211 ± 1.73
0.0IleXaa: 0.0 ± 0.0
Lys
4.211LysAla: 4.211 ± 1.735
1.404LysCys: 1.404 ± 1.387
1.404LysAsp: 1.404 ± 1.78
1.404LysGlu: 1.404 ± 0.913
3.509LysPhe: 3.509 ± 1.207
3.509LysGly: 3.509 ± 1.678
1.404LysHis: 1.404 ± 1.024
2.807LysIle: 2.807 ± 1.187
4.211LysLys: 4.211 ± 2.304
5.614LysLeu: 5.614 ± 2.154
2.807LysMet: 2.807 ± 2.296
2.807LysAsn: 2.807 ± 1.104
2.807LysPro: 2.807 ± 1.773
3.509LysGln: 3.509 ± 2.015
4.211LysArg: 4.211 ± 1.807
4.912LysSer: 4.912 ± 2.491
2.807LysThr: 2.807 ± 1.023
2.807LysVal: 2.807 ± 1.293
0.0LysTrp: 0.0 ± 0.0
1.404LysTyr: 1.404 ± 0.975
0.0LysXaa: 0.0 ± 0.0
Leu
6.316LeuAla: 6.316 ± 2.341
0.0LeuCys: 0.0 ± 0.0
7.018LeuAsp: 7.018 ± 2.303
2.105LeuGlu: 2.105 ± 0.834
4.912LeuPhe: 4.912 ± 2.506
7.018LeuGly: 7.018 ± 2.178
0.702LeuHis: 0.702 ± 0.642
4.211LeuIle: 4.211 ± 1.373
4.912LeuLys: 4.912 ± 1.694
2.807LeuLeu: 2.807 ± 1.204
2.807LeuMet: 2.807 ± 1.33
4.211LeuAsn: 4.211 ± 1.466
8.421LeuPro: 8.421 ± 1.291
4.912LeuGln: 4.912 ± 1.379
7.719LeuArg: 7.719 ± 2.787
4.912LeuSer: 4.912 ± 0.915
5.614LeuThr: 5.614 ± 1.687
1.404LeuVal: 1.404 ± 1.284
0.702LeuTrp: 0.702 ± 0.642
2.807LeuTyr: 2.807 ± 1.023
0.0LeuXaa: 0.0 ± 0.0
Met
2.807MetAla: 2.807 ± 1.266
0.702MetCys: 0.702 ± 0.642
2.807MetAsp: 2.807 ± 1.795
2.105MetGlu: 2.105 ± 1.153
0.702MetPhe: 0.702 ± 0.89
0.702MetGly: 0.702 ± 0.457
1.404MetHis: 1.404 ± 1.234
0.0MetIle: 0.0 ± 0.0
2.105MetLys: 2.105 ± 1.504
2.807MetLeu: 2.807 ± 2.131
0.0MetMet: 0.0 ± 0.0
2.105MetAsn: 2.105 ± 1.482
0.702MetPro: 0.702 ± 0.457
2.105MetGln: 2.105 ± 1.278
2.105MetArg: 2.105 ± 2.697
2.105MetSer: 2.105 ± 1.223
0.702MetThr: 0.702 ± 0.642
1.404MetVal: 1.404 ± 1.024
1.404MetTrp: 1.404 ± 1.191
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
4.211AsnAla: 4.211 ± 0.952
1.404AsnCys: 1.404 ± 1.387
1.404AsnAsp: 1.404 ± 0.97
1.404AsnGlu: 1.404 ± 1.024
0.702AsnPhe: 0.702 ± 0.457
2.105AsnGly: 2.105 ± 1.158
0.0AsnHis: 0.0 ± 0.0
2.105AsnIle: 2.105 ± 1.111
2.105AsnLys: 2.105 ± 1.111
4.211AsnLeu: 4.211 ± 1.812
0.0AsnMet: 0.0 ± 0.0
2.105AsnAsn: 2.105 ± 0.991
4.912AsnPro: 4.912 ± 2.018
4.211AsnGln: 4.211 ± 0.858
2.105AsnArg: 2.105 ± 1.437
4.211AsnSer: 4.211 ± 1.634
1.404AsnThr: 1.404 ± 1.633
2.807AsnVal: 2.807 ± 1.795
0.0AsnTrp: 0.0 ± 0.0
3.509AsnTyr: 3.509 ± 1.207
0.0AsnXaa: 0.0 ± 0.0
Pro
3.509ProAla: 3.509 ± 1.233
0.702ProCys: 0.702 ± 0.642
2.105ProAsp: 2.105 ± 0.855
6.316ProGlu: 6.316 ± 2.729
2.105ProPhe: 2.105 ± 1.5
4.211ProGly: 4.211 ± 0.909
2.105ProHis: 2.105 ± 1.158
2.807ProIle: 2.807 ± 1.826
2.105ProLys: 2.105 ± 1.345
2.807ProLeu: 2.807 ± 1.023
2.807ProMet: 2.807 ± 1.036
0.702ProAsn: 0.702 ± 0.816
1.404ProPro: 1.404 ± 0.602
4.912ProGln: 4.912 ± 1.971
4.211ProArg: 4.211 ± 2.431
2.105ProSer: 2.105 ± 1.37
2.807ProThr: 2.807 ± 1.476
4.912ProVal: 4.912 ± 2.116
2.105ProTrp: 2.105 ± 1.201
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
3.509GlnAla: 3.509 ± 1.528
0.702GlnCys: 0.702 ± 0.457
4.211GlnAsp: 4.211 ± 2.316
4.211GlnGlu: 4.211 ± 1.795
1.404GlnPhe: 1.404 ± 1.384
3.509GlnGly: 3.509 ± 1.625
0.702GlnHis: 0.702 ± 0.89
1.404GlnIle: 1.404 ± 0.732
4.912GlnLys: 4.912 ± 1.987
2.807GlnLeu: 2.807 ± 1.188
2.807GlnMet: 2.807 ± 1.524
4.211GlnAsn: 4.211 ± 2.588
1.404GlnPro: 1.404 ± 1.126
2.105GlnGln: 2.105 ± 1.288
4.912GlnArg: 4.912 ± 1.88
2.807GlnSer: 2.807 ± 1.231
2.105GlnThr: 2.105 ± 1.111
2.105GlnVal: 2.105 ± 1.078
0.0GlnTrp: 0.0 ± 0.0
2.105GlnTyr: 2.105 ± 0.855
0.0GlnXaa: 0.0 ± 0.0
Arg
4.211ArgAla: 4.211 ± 1.569
1.404ArgCys: 1.404 ± 0.602
4.912ArgAsp: 4.912 ± 1.765
5.614ArgGlu: 5.614 ± 2.526
4.211ArgPhe: 4.211 ± 1.766
2.807ArgGly: 2.807 ± 1.221
0.702ArgHis: 0.702 ± 0.642
3.509ArgIle: 3.509 ± 4.049
2.105ArgLys: 2.105 ± 2.063
10.526ArgLeu: 10.526 ± 4.635
3.509ArgMet: 3.509 ± 1.86
2.105ArgAsn: 2.105 ± 1.437
2.105ArgPro: 2.105 ± 1.158
0.702ArgGln: 0.702 ± 0.642
8.421ArgArg: 8.421 ± 7.303
5.614ArgSer: 5.614 ± 2.338
3.509ArgThr: 3.509 ± 1.795
4.912ArgVal: 4.912 ± 1.59
1.404ArgTrp: 1.404 ± 0.602
5.614ArgTyr: 5.614 ± 1.577
0.0ArgXaa: 0.0 ± 0.0
Ser
4.912SerAla: 4.912 ± 1.999
2.105SerCys: 2.105 ± 1.269
2.105SerAsp: 2.105 ± 1.548
2.807SerGlu: 2.807 ± 1.616
5.614SerPhe: 5.614 ± 3.445
4.912SerGly: 4.912 ± 2.93
2.105SerHis: 2.105 ± 1.37
1.404SerIle: 1.404 ± 0.916
4.912SerLys: 4.912 ± 1.765
7.719SerLeu: 7.719 ± 2.101
0.0SerMet: 0.0 ± 0.0
3.509SerAsn: 3.509 ± 1.625
6.316SerPro: 6.316 ± 1.84
2.105SerGln: 2.105 ± 1.158
5.614SerArg: 5.614 ± 3.63
7.719SerSer: 7.719 ± 2.444
4.912SerThr: 4.912 ± 1.961
4.912SerVal: 4.912 ± 1.971
2.105SerTrp: 2.105 ± 1.363
2.105SerTyr: 2.105 ± 1.5
0.0SerXaa: 0.0 ± 0.0
Thr
3.509ThrAla: 3.509 ± 1.898
0.702ThrCys: 0.702 ± 0.642
2.105ThrAsp: 2.105 ± 1.37
2.807ThrGlu: 2.807 ± 1.104
2.105ThrPhe: 2.105 ± 1.185
4.912ThrGly: 4.912 ± 3.112
0.0ThrHis: 0.0 ± 0.0
1.404ThrIle: 1.404 ± 0.913
3.509ThrLys: 3.509 ± 1.63
3.509ThrLeu: 3.509 ± 0.76
0.0ThrMet: 0.0 ± 0.0
0.702ThrAsn: 0.702 ± 0.816
3.509ThrPro: 3.509 ± 2.283
3.509ThrGln: 3.509 ± 1.609
2.807ThrArg: 2.807 ± 1.204
5.614ThrSer: 5.614 ± 2.367
3.509ThrThr: 3.509 ± 1.802
2.105ThrVal: 2.105 ± 0.974
0.0ThrTrp: 0.0 ± 0.0
2.105ThrTyr: 2.105 ± 1.605
0.0ThrXaa: 0.0 ± 0.0
Val
4.912ValAla: 4.912 ± 2.513
0.702ValCys: 0.702 ± 0.642
0.702ValAsp: 0.702 ± 0.457
2.807ValGlu: 2.807 ± 0.863
2.807ValPhe: 2.807 ± 2.048
2.105ValGly: 2.105 ± 0.855
0.0ValHis: 0.0 ± 0.0
1.404ValIle: 1.404 ± 0.897
4.211ValLys: 4.211 ± 1.614
6.316ValLeu: 6.316 ± 2.2
0.702ValMet: 0.702 ± 0.457
3.509ValAsn: 3.509 ± 1.25
3.509ValPro: 3.509 ± 1.286
4.211ValGln: 4.211 ± 1.17
3.509ValArg: 3.509 ± 1.731
2.105ValSer: 2.105 ± 0.749
2.807ValThr: 2.807 ± 1.231
2.105ValVal: 2.105 ± 1.383
0.0ValTrp: 0.0 ± 0.0
2.807ValTyr: 2.807 ± 0.931
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.702TrpCys: 0.702 ± 1.281
1.404TrpAsp: 1.404 ± 0.602
0.0TrpGlu: 0.0 ± 0.0
0.702TrpPhe: 0.702 ± 0.457
0.0TrpGly: 0.0 ± 0.0
1.404TrpHis: 1.404 ± 0.913
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
1.404TrpAsn: 1.404 ± 1.191
2.105TrpPro: 2.105 ± 0.855
0.0TrpGln: 0.0 ± 0.0
0.702TrpArg: 0.702 ± 1.281
3.509TrpSer: 3.509 ± 1.162
0.0TrpThr: 0.0 ± 0.0
0.702TrpVal: 0.702 ± 0.642
0.0TrpTrp: 0.0 ± 0.0
1.404TrpTyr: 1.404 ± 0.602
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.702TyrAla: 0.702 ± 0.457
0.702TyrCys: 0.702 ± 0.457
2.807TyrAsp: 2.807 ± 1.293
7.719TyrGlu: 7.719 ± 2.776
2.105TyrPhe: 2.105 ± 0.855
2.105TyrGly: 2.105 ± 1.158
0.702TyrHis: 0.702 ± 0.642
2.105TyrIle: 2.105 ± 0.974
1.404TyrLys: 1.404 ± 0.602
4.211TyrLeu: 4.211 ± 1.373
2.807TyrMet: 2.807 ± 0.877
2.105TyrAsn: 2.105 ± 0.855
2.105TyrPro: 2.105 ± 1.925
2.807TyrGln: 2.807 ± 1.104
3.509TyrArg: 3.509 ± 1.312
4.211TyrSer: 4.211 ± 1.838
1.404TyrThr: 1.404 ± 0.913
1.404TyrVal: 1.404 ± 0.602
0.702TyrTrp: 0.702 ± 0.457
2.105TyrTyr: 2.105 ± 0.855
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (1426 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski