Amino acid dipepetide frequency for Aurantiacibacter atlanticus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.511AlaAla: 15.511 ± 0.185	1.121AlaCys: 1.121 ± 0.038	7.136AlaAsp: 7.136 ± 0.095	7.913AlaGlu: 7.913 ± 0.105	4.234AlaPhe: 4.234 ± 0.067	10.154AlaGly: 10.154 ± 0.115	2.264AlaHis: 2.264 ± 0.054	6.994AlaIle: 6.994 ± 0.104	3.983AlaLys: 3.983 ± 0.087	12.922AlaLeu: 12.922 ± 0.174	3.926AlaMet: 3.926 ± 0.063	3.364AlaAsn: 3.364 ± 0.072	5.166AlaPro: 5.166 ± 0.081	4.869AlaGln: 4.869 ± 0.082	8.63AlaArg: 8.63 ± 0.112	6.84AlaSer: 6.84 ± 0.098	5.742AlaThr: 5.742 ± 0.095	7.51AlaVal: 7.51 ± 0.104	1.492AlaTrp: 1.492 ± 0.045	2.443AlaTyr: 2.443 ± 0.055	0.0AlaXaa: 0.0 ± 0.0
Cys	1.027CysAla: 1.027 ± 0.037	0.123CysCys: 0.123 ± 0.012	0.646CysAsp: 0.646 ± 0.027	0.56CysGlu: 0.56 ± 0.025	0.304CysPhe: 0.304 ± 0.016	0.907CysGly: 0.907 ± 0.035	0.215CysHis: 0.215 ± 0.014	0.401CysIle: 0.401 ± 0.021	0.21CysLys: 0.21 ± 0.017	0.73CysLeu: 0.73 ± 0.028	0.138CysMet: 0.138 ± 0.012	0.27CysAsn: 0.27 ± 0.016	0.486CysPro: 0.486 ± 0.027	0.236CysGln: 0.236 ± 0.018	0.58CysArg: 0.58 ± 0.025	0.536CysSer: 0.536 ± 0.023	0.393CysThr: 0.393 ± 0.021	0.59CysVal: 0.59 ± 0.028	0.11CysTrp: 0.11 ± 0.01	0.185CysTyr: 0.185 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	7.482AspAla: 7.482 ± 0.09	0.589AspCys: 0.589 ± 0.027	3.902AspAsp: 3.902 ± 0.076	4.163AspGlu: 4.163 ± 0.083	2.363AspPhe: 2.363 ± 0.05	5.691AspGly: 5.691 ± 0.091	1.354AspHis: 1.354 ± 0.048	3.435AspIle: 3.435 ± 0.071	1.832AspLys: 1.832 ± 0.046	6.016AspLeu: 6.016 ± 0.086	1.692AspMet: 1.692 ± 0.05	1.733AspAsn: 1.733 ± 0.041	3.546AspPro: 3.546 ± 0.057	1.862AspGln: 1.862 ± 0.04	4.472AspArg: 4.472 ± 0.077	2.732AspSer: 2.732 ± 0.058	2.918AspThr: 2.918 ± 0.063	4.055AspVal: 4.055 ± 0.077	1.102AspTrp: 1.102 ± 0.037	1.589AspTyr: 1.589 ± 0.037	0.0AspXaa: 0.0 ± 0.0
Glu	7.923GluAla: 7.923 ± 0.11	0.444GluCys: 0.444 ± 0.025	3.8GluAsp: 3.8 ± 0.074	4.142GluGlu: 4.142 ± 0.078	1.974GluPhe: 1.974 ± 0.043	4.924GluGly: 4.924 ± 0.071	1.32GluHis: 1.32 ± 0.037	3.539GluIle: 3.539 ± 0.058	2.376GluLys: 2.376 ± 0.066	5.806GluLeu: 5.806 ± 0.082	1.774GluMet: 1.774 ± 0.047	1.913GluAsn: 1.913 ± 0.049	2.681GluPro: 2.681 ± 0.056	2.485GluGln: 2.485 ± 0.057	5.105GluArg: 5.105 ± 0.092	2.874GluSer: 2.874 ± 0.058	3.633GluThr: 3.633 ± 0.057	3.971GluVal: 3.971 ± 0.069	0.921GluTrp: 0.921 ± 0.03	1.221GluTyr: 1.221 ± 0.039	0.0GluXaa: 0.0 ± 0.0
Phe	4.986PheAla: 4.986 ± 0.078	0.368PheCys: 0.368 ± 0.019	2.86PheAsp: 2.86 ± 0.059	2.246PheGlu: 2.246 ± 0.048	1.373PhePhe: 1.373 ± 0.046	3.563PheGly: 3.563 ± 0.065	0.715PheHis: 0.715 ± 0.03	1.799PheIle: 1.799 ± 0.052	0.865PheLys: 0.865 ± 0.035	3.265PheLeu: 3.265 ± 0.063	0.847PheMet: 0.847 ± 0.033	1.02PheAsn: 1.02 ± 0.039	1.597PhePro: 1.597 ± 0.039	0.891PheGln: 0.891 ± 0.03	2.019PheArg: 2.019 ± 0.046	2.298PheSer: 2.298 ± 0.049	2.109PheThr: 2.109 ± 0.05	2.634PheVal: 2.634 ± 0.055	0.584PheTrp: 0.584 ± 0.027	0.927PheTyr: 0.927 ± 0.034	0.0PheXaa: 0.0 ± 0.0
Gly	9.017GlyAla: 9.017 ± 0.091	0.821GlyCys: 0.821 ± 0.032	4.941GlyAsp: 4.941 ± 0.074	5.542GlyGlu: 5.542 ± 0.085	3.63GlyPhe: 3.63 ± 0.074	7.584GlyGly: 7.584 ± 0.13	1.745GlyHis: 1.745 ± 0.048	4.513GlyIle: 4.513 ± 0.077	3.436GlyLys: 3.436 ± 0.082	8.156GlyLeu: 8.156 ± 0.116	2.462GlyMet: 2.462 ± 0.052	2.568GlyAsn: 2.568 ± 0.065	3.39GlyPro: 3.39 ± 0.058	3.04GlyGln: 3.04 ± 0.054	5.711GlyArg: 5.711 ± 0.077	5.065GlySer: 5.065 ± 0.087	4.591GlyThr: 4.591 ± 0.081	5.837GlyVal: 5.837 ± 0.088	1.512GlyTrp: 1.512 ± 0.042	2.143GlyTyr: 2.143 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	2.2HisAla: 2.2 ± 0.048	0.255HisCys: 0.255 ± 0.017	1.277HisAsp: 1.277 ± 0.038	1.223HisGlu: 1.223 ± 0.038	0.884HisPhe: 0.884 ± 0.03	1.854HisGly: 1.854 ± 0.051	0.516HisHis: 0.516 ± 0.025	1.027HisIle: 1.027 ± 0.031	0.51HisLys: 0.51 ± 0.024	1.943HisLeu: 1.943 ± 0.046	0.443HisMet: 0.443 ± 0.022	0.492HisAsn: 0.492 ± 0.027	1.202HisPro: 1.202 ± 0.038	0.571HisGln: 0.571 ± 0.024	1.433HisArg: 1.433 ± 0.042	1.101HisSer: 1.101 ± 0.036	0.817HisThr: 0.817 ± 0.034	1.327HisVal: 1.327 ± 0.04	0.359HisTrp: 0.359 ± 0.022	0.546HisTyr: 0.546 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	8.117IleAla: 8.117 ± 0.099	0.539IleCys: 0.539 ± 0.025	3.917IleAsp: 3.917 ± 0.065	3.868IleGlu: 3.868 ± 0.069	1.78IlePhe: 1.78 ± 0.043	5.291IleGly: 5.291 ± 0.09	0.914IleHis: 0.914 ± 0.033	2.474IleIle: 2.474 ± 0.062	1.278IleLys: 1.278 ± 0.036	4.222IleLeu: 4.222 ± 0.073	1.105IleMet: 1.105 ± 0.035	1.441IleAsn: 1.441 ± 0.048	2.312IlePro: 2.312 ± 0.043	1.154IleGln: 1.154 ± 0.035	3.155IleArg: 3.155 ± 0.06	3.158IleSer: 3.158 ± 0.063	2.773IleThr: 2.773 ± 0.059	4.112IleVal: 4.112 ± 0.07	0.657IleTrp: 0.657 ± 0.03	1.088IleTyr: 1.088 ± 0.034	0.0IleXaa: 0.0 ± 0.0
Lys	3.687LysAla: 3.687 ± 0.086	0.199LysCys: 0.199 ± 0.015	1.659LysAsp: 1.659 ± 0.045	1.536LysGlu: 1.536 ± 0.051	0.88LysPhe: 0.88 ± 0.035	2.589LysGly: 2.589 ± 0.069	0.657LysHis: 0.657 ± 0.03	1.571LysIle: 1.571 ± 0.045	1.225LysLys: 1.225 ± 0.056	3.22LysLeu: 3.22 ± 0.068	0.78LysMet: 0.78 ± 0.029	0.861LysAsn: 0.861 ± 0.039	1.707LysPro: 1.707 ± 0.055	0.968LysGln: 0.968 ± 0.032	2.37LysArg: 2.37 ± 0.051	1.788LysSer: 1.788 ± 0.051	1.642LysThr: 1.642 ± 0.045	2.151LysVal: 2.151 ± 0.053	0.401LysTrp: 0.401 ± 0.02	0.584LysTyr: 0.584 ± 0.029	0.0LysXaa: 0.0 ± 0.0
Leu	13.666LeuAla: 13.666 ± 0.147	0.792LeuCys: 0.792 ± 0.029	6.202LeuAsp: 6.202 ± 0.082	5.825LeuGlu: 5.825 ± 0.084	3.596LeuPhe: 3.596 ± 0.071	8.022LeuGly: 8.022 ± 0.105	1.807LeuHis: 1.807 ± 0.038	4.789LeuIle: 4.789 ± 0.09	2.827LeuLys: 2.827 ± 0.064	9.607LeuLeu: 9.607 ± 0.153	2.203LeuMet: 2.203 ± 0.052	2.42LeuAsn: 2.42 ± 0.049	5.403LeuPro: 5.403 ± 0.086	2.885LeuGln: 2.885 ± 0.057	6.776LeuArg: 6.776 ± 0.094	6.214LeuSer: 6.214 ± 0.097	5.415LeuThr: 5.415 ± 0.084	7.187LeuVal: 7.187 ± 0.086	1.118LeuTrp: 1.118 ± 0.042	1.842LeuTyr: 1.842 ± 0.04	0.0LeuXaa: 0.0 ± 0.0
Met	3.374MetAla: 3.374 ± 0.066	0.173MetCys: 0.173 ± 0.015	1.35MetAsp: 1.35 ± 0.042	1.41MetGlu: 1.41 ± 0.041	0.834MetPhe: 0.834 ± 0.029	2.07MetGly: 2.07 ± 0.053	0.512MetHis: 0.512 ± 0.021	1.449MetIle: 1.449 ± 0.039	0.939MetLys: 0.939 ± 0.033	2.778MetLeu: 2.778 ± 0.068	0.76MetMet: 0.76 ± 0.032	0.808MetAsn: 0.808 ± 0.029	1.44MetPro: 1.44 ± 0.037	0.96MetGln: 0.96 ± 0.035	1.978MetArg: 1.978 ± 0.051	1.506MetSer: 1.506 ± 0.046	1.606MetThr: 1.606 ± 0.043	1.777MetVal: 1.777 ± 0.042	0.267MetTrp: 0.267 ± 0.018	0.303MetTyr: 0.303 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	3.331AsnAla: 3.331 ± 0.06	0.282AsnCys: 0.282 ± 0.019	1.584AsnAsp: 1.584 ± 0.043	1.421AsnGlu: 1.421 ± 0.035	1.006AsnPhe: 1.006 ± 0.034	2.545AsnGly: 2.545 ± 0.06	0.542AsnHis: 0.542 ± 0.023	1.47AsnIle: 1.47 ± 0.038	0.665AsnLys: 0.665 ± 0.026	2.76AsnLeu: 2.76 ± 0.055	0.673AsnMet: 0.673 ± 0.028	0.722AsnAsn: 0.722 ± 0.037	1.831AsnPro: 1.831 ± 0.047	0.835AsnGln: 0.835 ± 0.028	2.034AsnArg: 2.034 ± 0.053	1.56AsnSer: 1.56 ± 0.044	1.32AsnThr: 1.32 ± 0.041	2.058AsnVal: 2.058 ± 0.057	0.474AsnTrp: 0.474 ± 0.022	0.719AsnTyr: 0.719 ± 0.029	0.0AsnXaa: 0.0 ± 0.0
Pro	5.846ProAla: 5.846 ± 0.084	0.319ProCys: 0.319 ± 0.019	3.908ProAsp: 3.908 ± 0.071	3.903ProGlu: 3.903 ± 0.071	1.876ProPhe: 1.876 ± 0.043	4.179ProGly: 4.179 ± 0.078	1.022ProHis: 1.022 ± 0.031	2.525ProIle: 2.525 ± 0.054	1.319ProLys: 1.319 ± 0.043	4.642ProLeu: 4.642 ± 0.066	1.215ProMet: 1.215 ± 0.033	1.177ProAsn: 1.177 ± 0.037	2.493ProPro: 2.493 ± 0.078	1.775ProGln: 1.775 ± 0.048	2.723ProArg: 2.723 ± 0.053	2.685ProSer: 2.685 ± 0.048	2.241ProThr: 2.241 ± 0.051	3.894ProVal: 3.894 ± 0.065	0.637ProTrp: 0.637 ± 0.025	1.025ProTyr: 1.025 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	4.028GlnAla: 4.028 ± 0.076	0.274GlnCys: 0.274 ± 0.017	1.864GlnAsp: 1.864 ± 0.046	1.784GlnGlu: 1.784 ± 0.05	1.238GlnPhe: 1.238 ± 0.033	2.561GlnGly: 2.561 ± 0.056	0.691GlnHis: 0.691 ± 0.026	1.988GlnIle: 1.988 ± 0.047	0.91GlnLys: 0.91 ± 0.031	3.427GlnLeu: 3.427 ± 0.061	1.003GlnMet: 1.003 ± 0.034	0.868GlnAsn: 0.868 ± 0.035	1.806GlnPro: 1.806 ± 0.046	1.375GlnGln: 1.375 ± 0.036	2.534GlnArg: 2.534 ± 0.061	2.121GlnSer: 2.121 ± 0.047	1.655GlnThr: 1.655 ± 0.047	2.31GlnVal: 2.31 ± 0.05	0.436GlnTrp: 0.436 ± 0.025	0.673GlnTyr: 0.673 ± 0.026	0.0GlnXaa: 0.0 ± 0.0
Arg	7.545ArgAla: 7.545 ± 0.107	0.472ArgCys: 0.472 ± 0.024	4.206ArgAsp: 4.206 ± 0.07	4.66ArgGlu: 4.66 ± 0.075	2.952ArgPhe: 2.952 ± 0.063	4.847ArgGly: 4.847 ± 0.077	1.55ArgHis: 1.55 ± 0.045	4.061ArgIle: 4.061 ± 0.071	2.393ArgLys: 2.393 ± 0.056	7.518ArgLeu: 7.518 ± 0.114	1.942ArgMet: 1.942 ± 0.048	2.126ArgAsn: 2.126 ± 0.048	3.153ArgPro: 3.153 ± 0.059	2.551ArgGln: 2.551 ± 0.061	5.135ArgArg: 5.135 ± 0.1	3.87ArgSer: 3.87 ± 0.071	3.233ArgThr: 3.233 ± 0.068	4.346ArgVal: 4.346 ± 0.075	1.071ArgTrp: 1.071 ± 0.034	1.699ArgTyr: 1.699 ± 0.044	0.0ArgXaa: 0.0 ± 0.0
Ser	6.731SerAla: 6.731 ± 0.112	0.494SerCys: 0.494 ± 0.025	3.67SerAsp: 3.67 ± 0.068	3.306SerGlu: 3.306 ± 0.061	2.355SerPhe: 2.355 ± 0.056	5.713SerGly: 5.713 ± 0.081	1.059SerHis: 1.059 ± 0.036	2.884SerIle: 2.884 ± 0.058	1.566SerLys: 1.566 ± 0.046	5.496SerLeu: 5.496 ± 0.082	1.408SerMet: 1.408 ± 0.036	1.651SerAsn: 1.651 ± 0.048	2.79SerPro: 2.79 ± 0.057	1.966SerGln: 1.966 ± 0.047	3.828SerArg: 3.828 ± 0.066	3.406SerSer: 3.406 ± 0.068	2.776SerThr: 2.776 ± 0.061	3.736SerVal: 3.736 ± 0.065	0.874SerTrp: 0.874 ± 0.028	1.384SerTyr: 1.384 ± 0.043	0.0SerXaa: 0.0 ± 0.0
Thr	5.821ThrAla: 5.821 ± 0.082	0.439ThrCys: 0.439 ± 0.025	2.982ThrAsp: 2.982 ± 0.057	2.633ThrGlu: 2.633 ± 0.056	1.791ThrPhe: 1.791 ± 0.04	5.219ThrGly: 5.219 ± 0.082	0.955ThrHis: 0.955 ± 0.03	2.905ThrIle: 2.905 ± 0.058	1.271ThrLys: 1.271 ± 0.039	5.447ThrLeu: 5.447 ± 0.08	1.371ThrMet: 1.371 ± 0.042	1.381ThrAsn: 1.381 ± 0.045	3.021ThrPro: 3.021 ± 0.06	1.688ThrGln: 1.688 ± 0.044	3.335ThrArg: 3.335 ± 0.054	2.984ThrSer: 2.984 ± 0.057	2.47ThrThr: 2.47 ± 0.055	3.797ThrVal: 3.797 ± 0.074	0.535ThrTrp: 0.535 ± 0.026	1.178ThrTyr: 1.178 ± 0.036	0.0ThrXaa: 0.0 ± 0.0
Val	8.202ValAla: 8.202 ± 0.105	0.559ValCys: 0.559 ± 0.028	4.357ValAsp: 4.357 ± 0.075	4.755ValGlu: 4.755 ± 0.08	2.341ValPhe: 2.341 ± 0.058	5.071ValGly: 5.071 ± 0.079	1.298ValHis: 1.298 ± 0.042	3.928ValIle: 3.928 ± 0.067	1.883ValLys: 1.883 ± 0.048	6.706ValLeu: 6.706 ± 0.097	1.752ValMet: 1.752 ± 0.047	1.958ValAsn: 1.958 ± 0.051	3.705ValPro: 3.705 ± 0.058	2.104ValGln: 2.104 ± 0.049	4.487ValArg: 4.487 ± 0.072	4.136ValSer: 4.136 ± 0.066	4.185ValThr: 4.185 ± 0.065	4.911ValVal: 4.911 ± 0.081	0.791ValTrp: 0.791 ± 0.03	1.251ValTyr: 1.251 ± 0.041	0.0ValXaa: 0.0 ± 0.0
Trp	1.274TrpAla: 1.274 ± 0.038	0.125TrpCys: 0.125 ± 0.011	0.754TrpAsp: 0.754 ± 0.028	0.696TrpGlu: 0.696 ± 0.024	0.651TrpPhe: 0.651 ± 0.028	0.93TrpGly: 0.93 ± 0.033	0.371TrpHis: 0.371 ± 0.022	0.686TrpIle: 0.686 ± 0.027	0.447TrpLys: 0.447 ± 0.02	1.803TrpLeu: 1.803 ± 0.046	0.383TrpMet: 0.383 ± 0.019	0.45TrpAsn: 0.45 ± 0.02	0.654TrpPro: 0.654 ± 0.027	0.651TrpGln: 0.651 ± 0.027	1.208TrpArg: 1.208 ± 0.037	0.876TrpSer: 0.876 ± 0.028	0.696TrpThr: 0.696 ± 0.025	0.755TrpVal: 0.755 ± 0.029	0.244TrpTrp: 0.244 ± 0.017	0.261TrpTyr: 0.261 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.447TyrAla: 2.447 ± 0.047	0.255TyrCys: 0.255 ± 0.017	1.51TyrAsp: 1.51 ± 0.043	1.238TyrGlu: 1.238 ± 0.04	0.904TyrPhe: 0.904 ± 0.033	1.988TyrGly: 1.988 ± 0.04	0.474TyrHis: 0.474 ± 0.024	0.918TyrIle: 0.918 ± 0.036	0.543TyrLys: 0.543 ± 0.025	2.134TyrLeu: 2.134 ± 0.047	0.418TyrMet: 0.418 ± 0.023	0.61TyrAsn: 0.61 ± 0.027	1.019TyrPro: 1.019 ± 0.034	0.682TyrGln: 0.682 ± 0.026	1.819TyrArg: 1.819 ± 0.043	1.343TyrSer: 1.343 ± 0.038	1.007TyrThr: 1.007 ± 0.038	1.42TyrVal: 1.42 ± 0.039	0.33TyrTrp: 0.33 ± 0.019	0.634TyrTyr: 0.634 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3172 proteins (959350 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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