Amino acid dipepetide frequency for Tilletia walkeri

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	14.834AlaAla: 14.834 ± 0.135	0.835AlaCys: 0.835 ± 0.018	5.049AlaAsp: 5.049 ± 0.039	5.98AlaGlu: 5.98 ± 0.053	3.193AlaPhe: 3.193 ± 0.029	8.27AlaGly: 8.27 ± 0.063	2.239AlaHis: 2.239 ± 0.029	3.935AlaIle: 3.935 ± 0.037	4.199AlaLys: 4.199 ± 0.042	9.128AlaLeu: 9.128 ± 0.06	1.998AlaMet: 1.998 ± 0.021	3.099AlaAsn: 3.099 ± 0.029	6.444AlaPro: 6.444 ± 0.067	4.52AlaGln: 4.52 ± 0.044	6.293AlaArg: 6.293 ± 0.042	11.002AlaSer: 11.002 ± 0.076	6.125AlaThr: 6.125 ± 0.043	5.896AlaVal: 5.896 ± 0.045	1.097AlaTrp: 1.097 ± 0.02	1.995AlaTyr: 1.995 ± 0.025	0.0AlaXaa: 0.0 ± 0.0
Cys	0.835CysAla: 0.835 ± 0.015	0.155CysCys: 0.155 ± 0.007	0.474CysAsp: 0.474 ± 0.012	0.43CysGlu: 0.43 ± 0.009	0.36CysPhe: 0.36 ± 0.01	0.701CysGly: 0.701 ± 0.014	0.204CysHis: 0.204 ± 0.008	0.475CysIle: 0.475 ± 0.012	0.38CysLys: 0.38 ± 0.01	0.894CysLeu: 0.894 ± 0.016	0.182CysMet: 0.182 ± 0.006	0.277CysAsn: 0.277 ± 0.009	0.515CysPro: 0.515 ± 0.013	0.305CysGln: 0.305 ± 0.009	0.544CysArg: 0.544 ± 0.012	0.738CysSer: 0.738 ± 0.018	0.548CysThr: 0.548 ± 0.014	0.588CysVal: 0.588 ± 0.012	0.128CysTrp: 0.128 ± 0.006	0.237CysTyr: 0.237 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	5.54AspAla: 5.54 ± 0.045	0.461AspCys: 0.461 ± 0.011	5.169AspAsp: 5.169 ± 0.062	4.965AspGlu: 4.965 ± 0.054	1.824AspPhe: 1.824 ± 0.021	4.545AspGly: 4.545 ± 0.04	1.106AspHis: 1.106 ± 0.017	2.222AspIle: 2.222 ± 0.027	1.846AspLys: 1.846 ± 0.026	4.656AspLeu: 4.656 ± 0.038	0.982AspMet: 0.982 ± 0.015	1.44AspAsn: 1.44 ± 0.017	3.303AspPro: 3.303 ± 0.028	1.841AspGln: 1.841 ± 0.019	3.1AspArg: 3.1 ± 0.039	4.212AspSer: 4.212 ± 0.035	2.526AspThr: 2.526 ± 0.025	3.608AspVal: 3.608 ± 0.034	0.718AspTrp: 0.718 ± 0.014	1.135AspTyr: 1.135 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	6.023GluAla: 6.023 ± 0.058	0.465GluCys: 0.465 ± 0.011	4.59GluAsp: 4.59 ± 0.05	6.126GluGlu: 6.126 ± 0.075	1.391GluPhe: 1.391 ± 0.018	4.398GluGly: 4.398 ± 0.034	1.327GluHis: 1.327 ± 0.02	2.183GluIle: 2.183 ± 0.027	2.736GluLys: 2.736 ± 0.032	4.914GluLeu: 4.914 ± 0.044	1.242GluMet: 1.242 ± 0.016	1.559GluAsn: 1.559 ± 0.018	2.468GluPro: 2.468 ± 0.027	2.508GluGln: 2.508 ± 0.028	4.353GluArg: 4.353 ± 0.041	3.774GluSer: 3.774 ± 0.033	2.695GluThr: 2.695 ± 0.027	3.396GluVal: 3.396 ± 0.032	0.739GluTrp: 0.739 ± 0.014	1.175GluTyr: 1.175 ± 0.016	0.001GluXaa: 0.001 ± 0.0
Phe	2.986PheAla: 2.986 ± 0.029	0.407PheCys: 0.407 ± 0.008	2.042PheAsp: 2.042 ± 0.023	1.781PheGlu: 1.781 ± 0.021	1.306PhePhe: 1.306 ± 0.021	2.776PheGly: 2.776 ± 0.034	0.733PheHis: 0.733 ± 0.013	1.273PheIle: 1.273 ± 0.021	1.182PheLys: 1.182 ± 0.017	2.892PheLeu: 2.892 ± 0.034	0.557PheMet: 0.557 ± 0.011	1.091PheAsn: 1.091 ± 0.016	1.68PhePro: 1.68 ± 0.021	1.128PheGln: 1.128 ± 0.016	1.758PheArg: 1.758 ± 0.021	2.788PheSer: 2.788 ± 0.027	1.741PheThr: 1.741 ± 0.019	2.067PheVal: 2.067 ± 0.027	0.452PheTrp: 0.452 ± 0.011	0.767PheTyr: 0.767 ± 0.013	0.0PheXaa: 0.0 ± 0.0
Gly	7.697GlyAla: 7.697 ± 0.064	0.635GlyCys: 0.635 ± 0.013	3.712GlyAsp: 3.712 ± 0.035	3.889GlyGlu: 3.889 ± 0.038	2.352GlyPhe: 2.352 ± 0.026	9.902GlyGly: 9.902 ± 0.129	1.735GlyHis: 1.735 ± 0.023	2.917GlyIle: 2.917 ± 0.032	3.579GlyLys: 3.579 ± 0.038	6.011GlyLeu: 6.011 ± 0.04	1.734GlyMet: 1.734 ± 0.029	2.504GlyAsn: 2.504 ± 0.027	4.541GlyPro: 4.541 ± 0.05	2.949GlyGln: 2.949 ± 0.035	4.797GlyArg: 4.797 ± 0.036	8.411GlySer: 8.411 ± 0.083	4.619GlyThr: 4.619 ± 0.04	4.33GlyVal: 4.33 ± 0.036	0.988GlyTrp: 0.988 ± 0.017	1.665GlyTyr: 1.665 ± 0.026	0.0GlyXaa: 0.0 ± 0.0
His	2.23HisAla: 2.23 ± 0.023	0.226HisCys: 0.226 ± 0.007	1.123HisAsp: 1.123 ± 0.019	1.079HisGlu: 1.079 ± 0.016	0.862HisPhe: 0.862 ± 0.016	1.735HisGly: 1.735 ± 0.023	1.174HisHis: 1.174 ± 0.028	1.015HisIle: 1.015 ± 0.015	0.741HisLys: 0.741 ± 0.014	2.303HisLeu: 2.303 ± 0.024	0.395HisMet: 0.395 ± 0.009	0.699HisAsn: 0.699 ± 0.013	1.822HisPro: 1.822 ± 0.024	1.204HisGln: 1.204 ± 0.019	1.57HisArg: 1.57 ± 0.022	2.139HisSer: 2.139 ± 0.027	1.241HisThr: 1.241 ± 0.017	1.243HisVal: 1.243 ± 0.017	0.278HisTrp: 0.278 ± 0.008	0.507HisTyr: 0.507 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	3.848IleAla: 3.848 ± 0.032	0.496IleCys: 0.496 ± 0.012	2.382IleAsp: 2.382 ± 0.024	2.237IleGlu: 2.237 ± 0.028	1.473IlePhe: 1.473 ± 0.021	2.708IleGly: 2.708 ± 0.028	0.911IleHis: 0.911 ± 0.014	1.761IleIle: 1.761 ± 0.025	1.7IleLys: 1.7 ± 0.022	3.651IleLeu: 3.651 ± 0.034	0.72IleMet: 0.72 ± 0.014	1.325IleAsn: 1.325 ± 0.02	2.615IlePro: 2.615 ± 0.028	1.493IleGln: 1.493 ± 0.021	2.536IleArg: 2.536 ± 0.026	3.359IleSer: 3.359 ± 0.029	2.234IleThr: 2.234 ± 0.025	2.64IleVal: 2.64 ± 0.03	0.508IleTrp: 0.508 ± 0.012	0.91IleTyr: 0.91 ± 0.014	0.0IleXaa: 0.0 ± 0.0
Lys	4.507LysAla: 4.507 ± 0.045	0.343LysCys: 0.343 ± 0.01	2.368LysAsp: 2.368 ± 0.027	2.878LysGlu: 2.878 ± 0.037	1.007LysPhe: 1.007 ± 0.017	2.994LysGly: 2.994 ± 0.031	0.941LysHis: 0.941 ± 0.015	1.646LysIle: 1.646 ± 0.021	2.982LysLys: 2.982 ± 0.044	3.405LysLeu: 3.405 ± 0.029	0.857LysMet: 0.857 ± 0.015	1.319LysAsn: 1.319 ± 0.02	2.151LysPro: 2.151 ± 0.031	1.58LysGln: 1.58 ± 0.023	3.275LysArg: 3.275 ± 0.03	3.048LysSer: 3.048 ± 0.033	2.433LysThr: 2.433 ± 0.024	2.483LysVal: 2.483 ± 0.028	0.48LysTrp: 0.48 ± 0.011	0.897LysTyr: 0.897 ± 0.014	0.0LysXaa: 0.0 ± 0.0
Leu	8.783LeuAla: 8.783 ± 0.055	0.991LeuCys: 0.991 ± 0.019	4.906LeuAsp: 4.906 ± 0.034	4.787LeuGlu: 4.787 ± 0.049	2.881LeuPhe: 2.881 ± 0.032	6.099LeuGly: 6.099 ± 0.042	2.124LeuHis: 2.124 ± 0.024	3.31LeuIle: 3.31 ± 0.034	3.451LeuLys: 3.451 ± 0.036	8.208LeuLeu: 8.208 ± 0.075	1.486LeuMet: 1.486 ± 0.02	2.868LeuAsn: 2.868 ± 0.028	6.067LeuPro: 6.067 ± 0.049	3.613LeuGln: 3.613 ± 0.036	6.071LeuArg: 6.071 ± 0.04	7.769LeuSer: 7.769 ± 0.053	4.671LeuThr: 4.671 ± 0.033	4.921LeuVal: 4.921 ± 0.04	0.932LeuTrp: 0.932 ± 0.015	1.796LeuTyr: 1.796 ± 0.022	0.0LeuXaa: 0.0 ± 0.0
Met	1.999MetAla: 1.999 ± 0.023	0.174MetCys: 0.174 ± 0.007	1.107MetAsp: 1.107 ± 0.017	1.076MetGlu: 1.076 ± 0.018	0.546MetPhe: 0.546 ± 0.011	1.537MetGly: 1.537 ± 0.027	0.436MetHis: 0.436 ± 0.009	0.689MetIle: 0.689 ± 0.014	0.672MetLys: 0.672 ± 0.013	1.734MetLeu: 1.734 ± 0.021	0.533MetMet: 0.533 ± 0.013	0.62MetAsn: 0.62 ± 0.012	1.283MetPro: 1.283 ± 0.022	0.798MetGln: 0.798 ± 0.015	1.279MetArg: 1.279 ± 0.018	1.924MetSer: 1.924 ± 0.024	1.147MetThr: 1.147 ± 0.017	1.039MetVal: 1.039 ± 0.016	0.194MetTrp: 0.194 ± 0.007	0.402MetTyr: 0.402 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.37AsnAla: 3.37 ± 0.028	0.277AsnCys: 0.277 ± 0.009	1.599AsnAsp: 1.599 ± 0.018	1.594AsnGlu: 1.594 ± 0.019	1.069AsnPhe: 1.069 ± 0.018	3.021AsnGly: 3.021 ± 0.034	0.658AsnHis: 0.658 ± 0.013	1.337AsnIle: 1.337 ± 0.02	1.279AsnLys: 1.279 ± 0.02	2.7AsnLeu: 2.7 ± 0.028	0.639AsnMet: 0.639 ± 0.012	1.381AsnAsn: 1.381 ± 0.028	2.067AsnPro: 2.067 ± 0.02	1.092AsnGln: 1.092 ± 0.016	1.734AsnArg: 1.734 ± 0.019	2.77AsnSer: 2.77 ± 0.03	1.893AsnThr: 1.893 ± 0.023	2.008AsnVal: 2.008 ± 0.024	0.361AsnTrp: 0.361 ± 0.009	0.668AsnTyr: 0.668 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	7.017ProAla: 7.017 ± 0.074	0.393ProCys: 0.393 ± 0.01	2.823ProAsp: 2.823 ± 0.024	3.129ProGlu: 3.129 ± 0.028	2.004ProPhe: 2.004 ± 0.021	4.422ProGly: 4.422 ± 0.051	1.497ProHis: 1.497 ± 0.021	2.439ProIle: 2.439 ± 0.023	2.195ProLys: 2.195 ± 0.023	4.978ProLeu: 4.978 ± 0.041	1.027ProMet: 1.027 ± 0.019	2.021ProAsn: 2.021 ± 0.025	6.351ProPro: 6.351 ± 0.083	2.508ProGln: 2.508 ± 0.03	3.481ProArg: 3.481 ± 0.038	8.17ProSer: 8.17 ± 0.074	4.699ProThr: 4.699 ± 0.044	3.538ProVal: 3.538 ± 0.03	0.562ProTrp: 0.562 ± 0.012	1.263ProTyr: 1.263 ± 0.02	0.0ProXaa: 0.0 ± 0.0
Gln	4.238GlnAla: 4.238 ± 0.037	0.331GlnCys: 0.331 ± 0.012	2.075GlnAsp: 2.075 ± 0.027	2.226GlnGlu: 2.226 ± 0.029	0.988GlnPhe: 0.988 ± 0.017	2.785GlnGly: 2.785 ± 0.029	1.423GlnHis: 1.423 ± 0.025	1.545GlnIle: 1.545 ± 0.02	1.531GlnLys: 1.531 ± 0.023	3.489GlnLeu: 3.489 ± 0.034	0.82GlnMet: 0.82 ± 0.015	1.224GlnAsn: 1.224 ± 0.022	2.757GlnPro: 2.757 ± 0.036	4.337GlnGln: 4.337 ± 0.12	2.999GlnArg: 2.999 ± 0.031	3.288GlnSer: 3.288 ± 0.034	2.236GlnThr: 2.236 ± 0.024	2.186GlnVal: 2.186 ± 0.026	0.421GlnTrp: 0.421 ± 0.009	0.882GlnTyr: 0.882 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	6.345ArgAla: 6.345 ± 0.041	0.597ArgCys: 0.597 ± 0.013	3.147ArgAsp: 3.147 ± 0.033	3.679ArgGlu: 3.679 ± 0.037	2.029ArgPhe: 2.029 ± 0.022	4.063ArgGly: 4.063 ± 0.039	1.472ArgHis: 1.472 ± 0.02	2.789ArgIle: 2.789 ± 0.024	3.375ArgLys: 3.375 ± 0.032	5.594ArgLeu: 5.594 ± 0.044	1.386ArgMet: 1.386 ± 0.017	2.022ArgAsn: 2.022 ± 0.021	3.948ArgPro: 3.948 ± 0.039	2.67ArgGln: 2.67 ± 0.026	5.874ArgArg: 5.874 ± 0.051	6.118ArgSer: 6.118 ± 0.049	3.968ArgThr: 3.968 ± 0.035	3.324ArgVal: 3.324 ± 0.028	0.838ArgTrp: 0.838 ± 0.015	1.35ArgTyr: 1.35 ± 0.02	0.0ArgXaa: 0.0 ± 0.0
Ser	10.768SerAla: 10.768 ± 0.075	0.617SerCys: 0.617 ± 0.014	4.441SerAsp: 4.441 ± 0.035	4.053SerGlu: 4.053 ± 0.039	2.936SerPhe: 2.936 ± 0.027	7.824SerGly: 7.824 ± 0.072	2.145SerHis: 2.145 ± 0.027	3.69SerIle: 3.69 ± 0.029	3.736SerLys: 3.736 ± 0.036	7.459SerLeu: 7.459 ± 0.046	1.826SerMet: 1.826 ± 0.021	3.308SerAsn: 3.308 ± 0.033	6.391SerPro: 6.391 ± 0.072	3.577SerGln: 3.577 ± 0.039	5.685SerArg: 5.685 ± 0.053	15.609SerSer: 15.609 ± 0.151	7.667SerThr: 7.667 ± 0.065	4.88SerVal: 4.88 ± 0.035	0.894SerTrp: 0.894 ± 0.016	1.777SerTyr: 1.777 ± 0.021	0.0SerXaa: 0.0 ± 0.0
Thr	6.596ThrAla: 6.596 ± 0.042	0.537ThrCys: 0.537 ± 0.014	2.723ThrAsp: 2.723 ± 0.026	2.699ThrGlu: 2.699 ± 0.025	2.032ThrPhe: 2.032 ± 0.023	4.346ThrGly: 4.346 ± 0.036	1.311ThrHis: 1.311 ± 0.019	2.492ThrIle: 2.492 ± 0.028	2.195ThrLys: 2.195 ± 0.027	5.183ThrLeu: 5.183 ± 0.039	1.105ThrMet: 1.105 ± 0.016	1.819ThrAsn: 1.819 ± 0.022	4.67ThrPro: 4.67 ± 0.045	2.044ThrGln: 2.044 ± 0.02	3.317ThrArg: 3.317 ± 0.029	7.057ThrSer: 7.057 ± 0.065	4.984ThrThr: 4.984 ± 0.063	3.43ThrVal: 3.43 ± 0.029	0.621ThrTrp: 0.621 ± 0.013	1.241ThrTyr: 1.241 ± 0.019	0.001ThrXaa: 0.001 ± 0.0
Val	5.486ValAla: 5.486 ± 0.039	0.615ValCys: 0.615 ± 0.013	3.481ValAsp: 3.481 ± 0.03	3.637ValGlu: 3.637 ± 0.031	1.948ValPhe: 1.948 ± 0.026	4.401ValGly: 4.401 ± 0.039	1.333ValHis: 1.333 ± 0.018	2.344ValIle: 2.344 ± 0.027	2.502ValLys: 2.502 ± 0.029	5.534ValLeu: 5.534 ± 0.049	1.046ValMet: 1.046 ± 0.015	1.753ValAsn: 1.753 ± 0.02	3.802ValPro: 3.802 ± 0.034	2.344ValGln: 2.344 ± 0.026	3.789ValArg: 3.789 ± 0.03	4.561ValSer: 4.561 ± 0.035	3.022ValThr: 3.022 ± 0.028	3.855ValVal: 3.855 ± 0.035	0.697ValTrp: 0.697 ± 0.012	1.212ValTyr: 1.212 ± 0.018	0.001ValXaa: 0.001 ± 0.0
Trp	1.037TrpAla: 1.037 ± 0.015	0.147TrpCys: 0.147 ± 0.006	0.711TrpAsp: 0.711 ± 0.014	0.643TrpGlu: 0.643 ± 0.013	0.377TrpPhe: 0.377 ± 0.011	0.691TrpGly: 0.691 ± 0.013	0.264TrpHis: 0.264 ± 0.008	0.541TrpIle: 0.541 ± 0.014	0.574TrpLys: 0.574 ± 0.011	1.051TrpLeu: 1.051 ± 0.018	0.271TrpMet: 0.271 ± 0.008	0.448TrpAsn: 0.448 ± 0.011	0.52TrpPro: 0.52 ± 0.012	0.434TrpGln: 0.434 ± 0.01	0.828TrpArg: 0.828 ± 0.016	0.928TrpSer: 0.928 ± 0.016	0.775TrpThr: 0.775 ± 0.013	0.66TrpVal: 0.66 ± 0.012	0.213TrpTrp: 0.213 ± 0.007	0.281TrpTyr: 0.281 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.99TyrAla: 1.99 ± 0.022	0.268TyrCys: 0.268 ± 0.008	1.275TyrAsp: 1.275 ± 0.018	1.172TyrGlu: 1.172 ± 0.017	0.828TyrPhe: 0.828 ± 0.014	1.75TyrGly: 1.75 ± 0.025	0.553TyrHis: 0.553 ± 0.012	0.904TyrIle: 0.904 ± 0.014	0.739TyrLys: 0.739 ± 0.014	1.951TyrLeu: 1.951 ± 0.023	0.383TyrMet: 0.383 ± 0.009	0.74TyrAsn: 0.74 ± 0.014	1.124TyrPro: 1.124 ± 0.02	0.836TyrGln: 0.836 ± 0.015	1.304TyrArg: 1.304 ± 0.021	1.618TyrSer: 1.618 ± 0.021	1.179TyrThr: 1.179 ± 0.019	1.271TyrVal: 1.271 ± 0.018	0.274TyrTrp: 0.274 ± 0.009	0.576TyrTyr: 0.576 ± 0.012	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.001XaaMet: 0.001 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.057XaaXaa: 0.057 ± 0.014

Statistics based on 7968 proteins (4572796 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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