Human circovirus VS6600022

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Arfiviricetes; Cirlivirales; Circoviridae; Circovirus; unclassified Circovirus

Average proteome isoelectric point is 7.87

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 4 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A0A0Q923|A0A0A0Q923_9CIRC Uncharacterized protein OS=Human circovirus VS6600022 OX=1525173 PE=4 SV=1
MM1 pKa = 7.54VYY3 pKa = 10.52NSSGKK8 pKa = 7.93YY9 pKa = 8.88RR10 pKa = 11.84KK11 pKa = 10.18VFVTSFNTSAMEE23 pKa = 4.06ALNIQDD29 pKa = 6.01LVDD32 pKa = 4.32CDD34 pKa = 3.54VARR37 pKa = 11.84YY38 pKa = 9.47VCMSMEE44 pKa = 4.37HH45 pKa = 6.7APTTGRR51 pKa = 11.84IHH53 pKa = 5.3YY54 pKa = 9.25HH55 pKa = 6.45LYY57 pKa = 10.23IEE59 pKa = 5.44FYY61 pKa = 9.73SQKK64 pKa = 9.59TMNTIKK70 pKa = 10.66KK71 pKa = 8.96ILKK74 pKa = 9.84DD75 pKa = 3.26ATANIQPARR84 pKa = 11.84GTPQEE89 pKa = 3.91AVDD92 pKa = 4.03YY93 pKa = 10.0IKK95 pKa = 10.92KK96 pKa = 10.65DD97 pKa = 3.0GATWKK102 pKa = 10.42EE103 pKa = 3.81AGTMSNQGHH112 pKa = 6.77RR113 pKa = 11.84SDD115 pKa = 5.3LDD117 pKa = 3.87DD118 pKa = 3.57VFQRR122 pKa = 11.84LQVGDD127 pKa = 4.46NILDD131 pKa = 4.09IIEE134 pKa = 4.3GHH136 pKa = 7.13PGTCIRR142 pKa = 11.84YY143 pKa = 8.83IKK145 pKa = 10.47GILAVKK151 pKa = 10.28GLVDD155 pKa = 3.89QRR157 pKa = 11.84RR158 pKa = 11.84QRR160 pKa = 11.84QEE162 pKa = 3.36ARR164 pKa = 11.84QMPTVLVYY172 pKa = 10.37IGKK175 pKa = 9.44SGAGKK180 pKa = 9.6SHH182 pKa = 7.1ACSQDD187 pKa = 2.76PDD189 pKa = 3.99YY190 pKa = 11.29QRR192 pKa = 11.84SGYY195 pKa = 9.38KK196 pKa = 10.22YY197 pKa = 9.54PVQGPSKK204 pKa = 10.69VYY206 pKa = 9.11FDD208 pKa = 4.88GYY210 pKa = 9.38TGEE213 pKa = 4.09STIWFDD219 pKa = 3.54EE220 pKa = 4.49FGGSVLPFHH229 pKa = 6.85VFLRR233 pKa = 11.84LADD236 pKa = 3.7KK237 pKa = 11.35YY238 pKa = 7.39EE239 pKa = 4.07TRR241 pKa = 11.84VEE243 pKa = 4.3TKK245 pKa = 10.31GGSVCITGLQKK256 pKa = 10.55ILISTTTPPKK266 pKa = 10.39LWWCEE271 pKa = 3.63SRR273 pKa = 11.84KK274 pKa = 9.97FNEE277 pKa = 4.98DD278 pKa = 3.31PYY280 pKa = 10.53QLWRR284 pKa = 11.84RR285 pKa = 11.84LTRR288 pKa = 11.84VYY290 pKa = 10.29YY291 pKa = 9.94IPRR294 pKa = 11.84PSWGFADD301 pKa = 3.87PVLIQHH307 pKa = 6.81PEE309 pKa = 3.83NFDD312 pKa = 3.62EE313 pKa = 5.71LVAAQLEE320 pKa = 4.71RR321 pKa = 11.84EE322 pKa = 4.34AEE324 pKa = 4.18TRR326 pKa = 11.84GPSLDD331 pKa = 3.68GEE333 pKa = 4.69SVRR336 pKa = 11.84GQPGPVDD343 pKa = 3.51PVHH346 pKa = 6.65EE347 pKa = 5.14RR348 pKa = 11.84DD349 pKa = 4.31DD350 pKa = 5.3DD351 pKa = 4.47SDD353 pKa = 4.06SEE355 pKa = 4.34RR356 pKa = 11.84TIDD359 pKa = 3.59TSDD362 pKa = 4.03GEE364 pKa = 4.54HH365 pKa = 6.23STTAAA370 pKa = 3.51

Molecular weight: 41.82 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A0A0Q9Q5|A0A0A0Q9Q5_9CIRC Capsid protein OS=Human circovirus VS6600022 OX=1525173 PE=4 SV=1
MM1 pKa = 6.93VRR3 pKa = 11.84RR4 pKa = 11.84RR5 pKa = 11.84YY6 pKa = 9.62RR7 pKa = 11.84KK8 pKa = 8.01RR9 pKa = 11.84GRR11 pKa = 11.84RR12 pKa = 11.84RR13 pKa = 11.84RR14 pKa = 11.84RR15 pKa = 11.84RR16 pKa = 11.84VYY18 pKa = 10.41RR19 pKa = 11.84KK20 pKa = 9.33VRR22 pKa = 11.84LSKK25 pKa = 10.27SLYY28 pKa = 7.83RR29 pKa = 11.84RR30 pKa = 11.84KK31 pKa = 9.46IRR33 pKa = 11.84RR34 pKa = 11.84RR35 pKa = 11.84YY36 pKa = 7.67RR37 pKa = 11.84GKK39 pKa = 10.02RR40 pKa = 11.84RR41 pKa = 11.84GRR43 pKa = 11.84GMTVSGTRR51 pKa = 11.84EE52 pKa = 4.0SQLVDD57 pKa = 3.38CSFIPLAKK65 pKa = 9.63PVLGTDD71 pKa = 2.86VGTPPGGFYY80 pKa = 9.53TWNINPLPTSVVNIPGDD97 pKa = 3.74PKK99 pKa = 10.93FVGAWSSDD107 pKa = 3.2PKK109 pKa = 11.0NILIRR114 pKa = 11.84QIGVGPNGTTEE125 pKa = 3.87TRR127 pKa = 11.84MLTDD131 pKa = 3.31MPVCISNVSVKK142 pKa = 10.86NIVRR146 pKa = 11.84CEE148 pKa = 4.23TMWKK152 pKa = 9.34LHH154 pKa = 5.4KK155 pKa = 10.14LYY157 pKa = 10.58RR158 pKa = 11.84ITFVSCTFTVPEE170 pKa = 4.01FTEE173 pKa = 4.57GKK175 pKa = 9.81RR176 pKa = 11.84NHH178 pKa = 6.19NLYY181 pKa = 10.82LEE183 pKa = 4.46WTHH186 pKa = 6.96LPRR189 pKa = 11.84GRR191 pKa = 11.84CAAYY195 pKa = 9.52EE196 pKa = 4.22DD197 pKa = 4.51CNGMVVGSAASSMNSFGFNWIVNPPDD223 pKa = 3.31IAEE226 pKa = 4.31ACCPDD231 pKa = 3.23GRR233 pKa = 11.84NNRR236 pKa = 11.84LNGWHH241 pKa = 6.72RR242 pKa = 11.84RR243 pKa = 11.84QLAYY247 pKa = 10.53NRR249 pKa = 11.84PVTISWRR256 pKa = 11.84PRR258 pKa = 11.84HH259 pKa = 5.14TNILEE264 pKa = 3.86DD265 pKa = 3.57HH266 pKa = 6.2QNYY269 pKa = 9.87LDD271 pKa = 4.48SIGSSGQGTMRR282 pKa = 11.84VLDD285 pKa = 3.65HH286 pKa = 7.11FGTKK290 pKa = 9.65NKK292 pKa = 9.33MIRR295 pKa = 11.84GYY297 pKa = 10.93LPTDD301 pKa = 3.05VDD303 pKa = 3.73QNIFDD308 pKa = 4.34EE309 pKa = 4.7RR310 pKa = 11.84QFWMGPVIRR319 pKa = 11.84LVDD322 pKa = 3.79ADD324 pKa = 4.69MPISDD329 pKa = 4.17QGGGINNKK337 pKa = 9.58SLFDD341 pKa = 3.66VYY343 pKa = 10.56GVRR346 pKa = 11.84VSTLVKK352 pKa = 10.85VKK354 pKa = 10.45FKK356 pKa = 11.41DD357 pKa = 3.48MNTTDD362 pKa = 4.07PLFPEE367 pKa = 4.61YY368 pKa = 11.07VPP370 pKa = 4.74

Molecular weight: 42.49 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

4

0

4

1250

195

370

312.5

35.58

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

4.16 ± 0.657

1.52 ± 0.359

4.72 ± 1.384

3.36 ± 1.094

2.8 ± 0.43

6.08 ± 1.214

3.36 ± 0.785

7.2 ± 1.677

4.96 ± 0.276

6.56 ± 0.494

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.72 ± 0.514

4.72 ± 0.933

6.88 ± 0.858

4.16 ± 0.698

9.12 ± 1.518

8.4 ± 1.58

8.64 ± 1.707

5.6 ± 1.228

1.52 ± 0.359

3.52 ± 0.522
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski