Amino acid dipepetide frequency for Arachidicoccus soli

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.597AlaAla: 5.597 ± 0.088	0.678AlaCys: 0.678 ± 0.025	3.716AlaAsp: 3.716 ± 0.061	3.924AlaGlu: 3.924 ± 0.066	3.539AlaPhe: 3.539 ± 0.058	4.693AlaGly: 4.693 ± 0.063	1.293AlaHis: 1.293 ± 0.032	5.715AlaIle: 5.715 ± 0.085	4.971AlaLys: 4.971 ± 0.065	6.521AlaLeu: 6.521 ± 0.09	1.683AlaMet: 1.683 ± 0.039	3.928AlaAsn: 3.928 ± 0.071	2.242AlaPro: 2.242 ± 0.044	2.862AlaGln: 2.862 ± 0.044	2.255AlaArg: 2.255 ± 0.046	4.422AlaSer: 4.422 ± 0.064	4.015AlaThr: 4.015 ± 0.059	4.122AlaVal: 4.122 ± 0.063	0.823AlaTrp: 0.823 ± 0.028	2.876AlaTyr: 2.876 ± 0.048	0.0AlaXaa: 0.0 ± 0.0
Cys	0.547CysAla: 0.547 ± 0.021	0.127CysCys: 0.127 ± 0.01	0.441CysAsp: 0.441 ± 0.018	0.437CysGlu: 0.437 ± 0.022	0.521CysPhe: 0.521 ± 0.022	0.702CysGly: 0.702 ± 0.027	0.177CysHis: 0.177 ± 0.014	0.758CysIle: 0.758 ± 0.03	0.549CysLys: 0.549 ± 0.024	0.876CysLeu: 0.876 ± 0.03	0.193CysMet: 0.193 ± 0.012	0.503CysAsn: 0.503 ± 0.022	0.339CysPro: 0.339 ± 0.018	0.248CysGln: 0.248 ± 0.015	0.329CysArg: 0.329 ± 0.018	0.594CysSer: 0.594 ± 0.026	0.47CysThr: 0.47 ± 0.022	0.486CysVal: 0.486 ± 0.018	0.118CysTrp: 0.118 ± 0.01	0.358CysTyr: 0.358 ± 0.021	0.0CysXaa: 0.0 ± 0.0
Asp	3.964AspAla: 3.964 ± 0.065	0.427AspCys: 0.427 ± 0.02	2.242AspAsp: 2.242 ± 0.052	3.021AspGlu: 3.021 ± 0.057	3.128AspPhe: 3.128 ± 0.054	3.515AspGly: 3.515 ± 0.069	0.806AspHis: 0.806 ± 0.027	4.263AspIle: 4.263 ± 0.059	4.004AspLys: 4.004 ± 0.077	4.629AspLeu: 4.629 ± 0.06	1.105AspMet: 1.105 ± 0.03	3.12AspAsn: 3.12 ± 0.069	1.763AspPro: 1.763 ± 0.046	1.312AspGln: 1.312 ± 0.038	1.815AspArg: 1.815 ± 0.041	3.463AspSer: 3.463 ± 0.064	2.665AspThr: 2.665 ± 0.051	3.058AspVal: 3.058 ± 0.057	0.937AspTrp: 0.937 ± 0.028	2.615AspTyr: 2.615 ± 0.051	0.0AspXaa: 0.0 ± 0.0
Glu	3.948GluAla: 3.948 ± 0.08	0.351GluCys: 0.351 ± 0.019	2.818GluAsp: 2.818 ± 0.052	3.859GluGlu: 3.859 ± 0.083	2.153GluPhe: 2.153 ± 0.041	3.32GluGly: 3.32 ± 0.048	1.025GluHis: 1.025 ± 0.033	4.625GluIle: 4.625 ± 0.076	5.483GluLys: 5.483 ± 0.075	5.171GluLeu: 5.171 ± 0.082	1.553GluMet: 1.553 ± 0.036	4.129GluAsn: 4.129 ± 0.072	1.388GluPro: 1.388 ± 0.034	2.175GluGln: 2.175 ± 0.051	2.291GluArg: 2.291 ± 0.049	2.747GluSer: 2.747 ± 0.048	2.842GluThr: 2.842 ± 0.057	3.357GluVal: 3.357 ± 0.054	0.709GluTrp: 0.709 ± 0.023	1.945GluTyr: 1.945 ± 0.044	0.0GluXaa: 0.0 ± 0.0
Phe	3.297PheAla: 3.297 ± 0.058	0.541PheCys: 0.541 ± 0.018	2.879PheAsp: 2.879 ± 0.051	2.722PheGlu: 2.722 ± 0.052	2.547PhePhe: 2.547 ± 0.059	3.451PheGly: 3.451 ± 0.063	0.914PheHis: 0.914 ± 0.027	3.812PheIle: 3.812 ± 0.07	3.291PheLys: 3.291 ± 0.051	4.625PheLeu: 4.625 ± 0.078	1.077PheMet: 1.077 ± 0.028	3.112PheAsn: 3.112 ± 0.064	1.971PhePro: 1.971 ± 0.04	1.589PheGln: 1.589 ± 0.036	1.648PheArg: 1.648 ± 0.033	3.985PheSer: 3.985 ± 0.064	2.906PheThr: 2.906 ± 0.05	2.885PheVal: 2.885 ± 0.054	0.708PheTrp: 0.708 ± 0.026	2.222PheTyr: 2.222 ± 0.048	0.0PheXaa: 0.0 ± 0.0
Gly	4.452GlyAla: 4.452 ± 0.067	0.631GlyCys: 0.631 ± 0.022	3.332GlyAsp: 3.332 ± 0.063	3.216GlyGlu: 3.216 ± 0.06	3.561GlyPhe: 3.561 ± 0.061	4.781GlyGly: 4.781 ± 0.095	1.271GlyHis: 1.271 ± 0.035	5.519GlyIle: 5.519 ± 0.083	5.4GlyLys: 5.4 ± 0.074	5.858GlyLeu: 5.858 ± 0.076	1.696GlyMet: 1.696 ± 0.039	4.099GlyAsn: 4.099 ± 0.063	1.39GlyPro: 1.39 ± 0.041	2.16GlyGln: 2.16 ± 0.043	2.352GlyArg: 2.352 ± 0.048	4.217GlySer: 4.217 ± 0.067	3.776GlyThr: 3.776 ± 0.071	4.232GlyVal: 4.232 ± 0.063	1.113GlyTrp: 1.113 ± 0.031	3.091GlyTyr: 3.091 ± 0.063	0.0GlyXaa: 0.0 ± 0.0
His	1.143HisAla: 1.143 ± 0.032	0.225HisCys: 0.225 ± 0.014	0.82HisAsp: 0.82 ± 0.03	0.865HisGlu: 0.865 ± 0.024	1.291HisPhe: 1.291 ± 0.033	1.131HisGly: 1.131 ± 0.03	0.58HisHis: 0.58 ± 0.022	1.584HisIle: 1.584 ± 0.036	1.201HisLys: 1.201 ± 0.032	2.07HisLeu: 2.07 ± 0.044	0.346HisMet: 0.346 ± 0.014	1.044HisAsn: 1.044 ± 0.026	1.074HisPro: 1.074 ± 0.03	0.862HisGln: 0.862 ± 0.03	0.761HisArg: 0.761 ± 0.029	1.285HisSer: 1.285 ± 0.031	1.006HisThr: 1.006 ± 0.026	0.887HisVal: 0.887 ± 0.027	0.331HisTrp: 0.331 ± 0.017	0.963HisTyr: 0.963 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	6.124IleAla: 6.124 ± 0.083	0.794IleCys: 0.794 ± 0.026	4.542IleAsp: 4.542 ± 0.069	4.606IleGlu: 4.606 ± 0.067	3.595IlePhe: 3.595 ± 0.065	5.159IleGly: 5.159 ± 0.073	1.612IleHis: 1.612 ± 0.04	6.092IleIle: 6.092 ± 0.1	5.682IleLys: 5.682 ± 0.07	6.87IleLeu: 6.87 ± 0.093	1.441IleMet: 1.441 ± 0.038	4.693IleAsn: 4.693 ± 0.071	3.254IlePro: 3.254 ± 0.054	2.797IleGln: 2.797 ± 0.054	2.888IleArg: 2.888 ± 0.049	5.594IleSer: 5.594 ± 0.072	4.482IleThr: 4.482 ± 0.071	4.581IleVal: 4.581 ± 0.066	0.819IleTrp: 0.819 ± 0.029	2.889IleTyr: 2.889 ± 0.041	0.0IleXaa: 0.0 ± 0.0
Lys	4.973LysAla: 4.973 ± 0.082	0.4LysCys: 0.4 ± 0.018	4.464LysAsp: 4.464 ± 0.061	5.597LysGlu: 5.597 ± 0.077	2.744LysPhe: 2.744 ± 0.049	4.738LysGly: 4.738 ± 0.071	1.339LysHis: 1.339 ± 0.034	6.089LysIle: 6.089 ± 0.078	6.374LysLys: 6.374 ± 0.087	6.075LysLeu: 6.075 ± 0.078	2.216LysMet: 2.216 ± 0.04	5.383LysAsn: 5.383 ± 0.073	2.563LysPro: 2.563 ± 0.048	2.938LysGln: 2.938 ± 0.051	2.781LysArg: 2.781 ± 0.044	4.141LysSer: 4.141 ± 0.057	4.256LysThr: 4.256 ± 0.068	4.297LysVal: 4.297 ± 0.063	0.894LysTrp: 0.894 ± 0.028	3.352LysTyr: 3.352 ± 0.053	0.0LysXaa: 0.0 ± 0.0
Leu	6.015LeuAla: 6.015 ± 0.082	0.878LeuCys: 0.878 ± 0.031	4.418LeuAsp: 4.418 ± 0.065	4.799LeuGlu: 4.799 ± 0.075	4.819LeuPhe: 4.819 ± 0.083	5.667LeuGly: 5.667 ± 0.079	2.005LeuHis: 2.005 ± 0.049	6.472LeuIle: 6.472 ± 0.086	7.352LeuLys: 7.352 ± 0.088	9.169LeuLeu: 9.169 ± 0.119	2.226LeuMet: 2.226 ± 0.051	5.889LeuAsn: 5.889 ± 0.065	4.222LeuPro: 4.222 ± 0.057	4.115LeuGln: 4.115 ± 0.071	3.534LeuArg: 3.534 ± 0.061	6.882LeuSer: 6.882 ± 0.091	4.668LeuThr: 4.668 ± 0.072	4.754LeuVal: 4.754 ± 0.062	1.032LeuTrp: 1.032 ± 0.032	3.464LeuTyr: 3.464 ± 0.057	0.0LeuXaa: 0.0 ± 0.0
Met	1.699MetAla: 1.699 ± 0.035	0.135MetCys: 0.135 ± 0.011	1.225MetAsp: 1.225 ± 0.032	1.374MetGlu: 1.374 ± 0.036	0.895MetPhe: 0.895 ± 0.025	1.516MetGly: 1.516 ± 0.035	0.513MetHis: 0.513 ± 0.021	1.544MetIle: 1.544 ± 0.036	1.993MetLys: 1.993 ± 0.039	2.132MetLeu: 2.132 ± 0.047	0.65MetMet: 0.65 ± 0.024	1.443MetAsn: 1.443 ± 0.035	1.02MetPro: 1.02 ± 0.033	1.264MetGln: 1.264 ± 0.034	1.037MetArg: 1.037 ± 0.027	1.432MetSer: 1.432 ± 0.034	1.06MetThr: 1.06 ± 0.029	1.274MetVal: 1.274 ± 0.031	0.236MetTrp: 0.236 ± 0.017	0.784MetTyr: 0.784 ± 0.026	0.0MetXaa: 0.0 ± 0.0
Asn	4.535AsnAla: 4.535 ± 0.063	0.5AsnCys: 0.5 ± 0.021	3.161AsnAsp: 3.161 ± 0.049	3.357AsnGlu: 3.357 ± 0.057	3.042AsnPhe: 3.042 ± 0.053	4.482AsnGly: 4.482 ± 0.071	1.159AsnHis: 1.159 ± 0.031	5.386AsnIle: 5.386 ± 0.071	4.724AsnLys: 4.724 ± 0.067	5.439AsnLeu: 5.439 ± 0.084	1.308AsnMet: 1.308 ± 0.035	4.228AsnAsn: 4.228 ± 0.076	2.848AsnPro: 2.848 ± 0.053	2.14AsnGln: 2.14 ± 0.043	2.16AsnArg: 2.16 ± 0.048	3.737AsnSer: 3.737 ± 0.068	3.532AsnThr: 3.532 ± 0.056	3.36AsnVal: 3.36 ± 0.06	0.927AsnTrp: 0.927 ± 0.033	3.025AsnTyr: 3.025 ± 0.06	0.0AsnXaa: 0.0 ± 0.0
Pro	2.551ProAla: 2.551 ± 0.044	0.241ProCys: 0.241 ± 0.015	2.196ProAsp: 2.196 ± 0.052	2.464ProGlu: 2.464 ± 0.047	2.021ProPhe: 2.021 ± 0.041	2.425ProGly: 2.425 ± 0.047	0.756ProHis: 0.756 ± 0.026	2.782ProIle: 2.782 ± 0.047	2.44ProLys: 2.44 ± 0.044	3.325ProLeu: 3.325 ± 0.047	0.801ProMet: 0.801 ± 0.027	2.346ProAsn: 2.346 ± 0.049	1.041ProPro: 1.041 ± 0.037	1.541ProGln: 1.541 ± 0.031	1.032ProArg: 1.032 ± 0.033	2.473ProSer: 2.473 ± 0.053	2.101ProThr: 2.101 ± 0.045	2.433ProVal: 2.433 ± 0.042	0.507ProTrp: 0.507 ± 0.022	1.672ProTyr: 1.672 ± 0.036	0.0ProXaa: 0.0 ± 0.0
Gln	2.493GlnAla: 2.493 ± 0.051	0.22GlnCys: 0.22 ± 0.013	1.61GlnAsp: 1.61 ± 0.041	2.059GlnGlu: 2.059 ± 0.05	1.716GlnPhe: 1.716 ± 0.04	1.973GlnGly: 1.973 ± 0.042	0.768GlnHis: 0.768 ± 0.026	2.901GlnIle: 2.901 ± 0.049	3.201GlnLys: 3.201 ± 0.049	3.874GlnLeu: 3.874 ± 0.07	1.008GlnMet: 1.008 ± 0.033	2.498GlnAsn: 2.498 ± 0.052	1.459GlnPro: 1.459 ± 0.029	2.145GlnGln: 2.145 ± 0.044	1.563GlnArg: 1.563 ± 0.041	2.439GlnSer: 2.439 ± 0.048	2.122GlnThr: 2.122 ± 0.04	2.001GlnVal: 2.001 ± 0.049	0.489GlnTrp: 0.489 ± 0.02	1.726GlnTyr: 1.726 ± 0.043	0.0GlnXaa: 0.0 ± 0.0
Arg	2.306ArgAla: 2.306 ± 0.043	0.258ArgCys: 0.258 ± 0.016	1.824ArgAsp: 1.824 ± 0.04	1.928ArgGlu: 1.928 ± 0.046	1.954ArgPhe: 1.954 ± 0.035	2.089ArgGly: 2.089 ± 0.044	0.628ArgHis: 0.628 ± 0.025	2.993ArgIle: 2.993 ± 0.056	2.971ArgLys: 2.971 ± 0.05	3.432ArgLeu: 3.432 ± 0.055	0.98ArgMet: 0.98 ± 0.027	2.327ArgAsn: 2.327 ± 0.044	1.232ArgPro: 1.232 ± 0.029	1.386ArgGln: 1.386 ± 0.037	1.443ArgArg: 1.443 ± 0.041	2.007ArgSer: 2.007 ± 0.044	1.893ArgThr: 1.893 ± 0.035	2.051ArgVal: 2.051 ± 0.044	0.582ArgTrp: 0.582 ± 0.024	1.613ArgTyr: 1.613 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	4.333SerAla: 4.333 ± 0.064	0.693SerCys: 0.693 ± 0.023	3.198SerAsp: 3.198 ± 0.055	3.12SerGlu: 3.12 ± 0.062	4.036SerPhe: 4.036 ± 0.062	4.767SerGly: 4.767 ± 0.08	1.128SerHis: 1.128 ± 0.032	5.393SerIle: 5.393 ± 0.068	4.301SerLys: 4.301 ± 0.064	6.546SerLeu: 6.546 ± 0.079	1.345SerMet: 1.345 ± 0.034	3.8SerAsn: 3.8 ± 0.064	2.355SerPro: 2.355 ± 0.047	2.157SerGln: 2.157 ± 0.046	2.149SerArg: 2.149 ± 0.045	4.545SerSer: 4.545 ± 0.072	3.648SerThr: 3.648 ± 0.065	3.849SerVal: 3.849 ± 0.06	0.9SerTrp: 0.9 ± 0.029	2.813SerTyr: 2.813 ± 0.053	0.0SerXaa: 0.0 ± 0.0
Thr	4.087ThrAla: 4.087 ± 0.06	0.447ThrCys: 0.447 ± 0.022	2.948ThrAsp: 2.948 ± 0.058	2.792ThrGlu: 2.792 ± 0.055	2.58ThrPhe: 2.58 ± 0.051	4.177ThrGly: 4.177 ± 0.06	1.106ThrHis: 1.106 ± 0.032	4.561ThrIle: 4.561 ± 0.063	3.51ThrLys: 3.51 ± 0.061	5.069ThrLeu: 5.069 ± 0.058	1.086ThrMet: 1.086 ± 0.033	3.232ThrAsn: 3.232 ± 0.061	2.594ThrPro: 2.594 ± 0.05	2.025ThrGln: 2.025 ± 0.038	1.678ThrArg: 1.678 ± 0.036	3.472ThrSer: 3.472 ± 0.067	3.47ThrThr: 3.47 ± 0.065	3.396ThrVal: 3.396 ± 0.053	0.695ThrTrp: 0.695 ± 0.027	2.289ThrTyr: 2.289 ± 0.047	0.0ThrXaa: 0.0 ± 0.0
Val	4.134ValAla: 4.134 ± 0.067	0.628ValCys: 0.628 ± 0.025	3.165ValAsp: 3.165 ± 0.049	3.123ValGlu: 3.123 ± 0.054	2.955ValPhe: 2.955 ± 0.059	3.64ValGly: 3.64 ± 0.067	1.112ValHis: 1.112 ± 0.03	4.369ValIle: 4.369 ± 0.064	4.109ValLys: 4.109 ± 0.056	5.416ValLeu: 5.416 ± 0.079	1.275ValMet: 1.275 ± 0.036	3.471ValAsn: 3.471 ± 0.062	2.238ValPro: 2.238 ± 0.047	2.07ValGln: 2.07 ± 0.037	2.006ValArg: 2.006 ± 0.039	3.998ValSer: 3.998 ± 0.067	3.123ValThr: 3.123 ± 0.06	3.601ValVal: 3.601 ± 0.061	0.706ValTrp: 0.706 ± 0.027	2.269ValTyr: 2.269 ± 0.049	0.0ValXaa: 0.0 ± 0.0
Trp	0.843TrpAla: 0.843 ± 0.027	0.173TrpCys: 0.173 ± 0.011	0.688TrpAsp: 0.688 ± 0.026	0.716TrpGlu: 0.716 ± 0.027	0.6TrpPhe: 0.6 ± 0.021	0.927TrpGly: 0.927 ± 0.03	0.346TrpHis: 0.346 ± 0.015	0.856TrpIle: 0.856 ± 0.031	0.977TrpLys: 0.977 ± 0.029	1.297TrpLeu: 1.297 ± 0.034	0.442TrpMet: 0.442 ± 0.019	0.888TrpAsn: 0.888 ± 0.028	0.366TrpPro: 0.366 ± 0.022	0.681TrpGln: 0.681 ± 0.026	0.576TrpArg: 0.576 ± 0.024	0.783TrpSer: 0.783 ± 0.027	0.693TrpThr: 0.693 ± 0.027	0.747TrpVal: 0.747 ± 0.028	0.253TrpTrp: 0.253 ± 0.017	0.572TrpTyr: 0.572 ± 0.025	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.833TyrAla: 2.833 ± 0.048	0.427TyrCys: 0.427 ± 0.02	2.164TyrAsp: 2.164 ± 0.046	1.909TyrGlu: 1.909 ± 0.045	2.485TyrPhe: 2.485 ± 0.044	2.993TyrGly: 2.993 ± 0.053	0.928TyrHis: 0.928 ± 0.03	2.799TyrIle: 2.799 ± 0.042	3.081TyrLys: 3.081 ± 0.053	3.986TyrLeu: 3.986 ± 0.065	0.793TyrMet: 0.793 ± 0.03	2.917TyrAsn: 2.917 ± 0.058	1.79TyrPro: 1.79 ± 0.037	1.802TyrGln: 1.802 ± 0.041	1.597TyrArg: 1.597 ± 0.039	2.86TyrSer: 2.86 ± 0.06	2.489TyrThr: 2.489 ± 0.047	2.041TyrVal: 2.041 ± 0.044	0.645TyrTrp: 0.645 ± 0.025	2.057TyrTyr: 2.057 ± 0.044	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3298 proteins (1183952 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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