Human papillomavirus 39

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Alphapapillomavirus; Alphapapillomavirus 7

Average proteome isoelectric point is 6.82

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 9 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>sp|P24838|VL1_HPV39 Major capsid protein L1 OS=Human papillomavirus 39 OX=10588 GN=L1 PE=3 SV=1
MM1 pKa = 7.92RR2 pKa = 11.84GPKK5 pKa = 8.48PTLQEE10 pKa = 4.0IVLDD14 pKa = 3.79LCPYY18 pKa = 10.95NEE20 pKa = 4.34IQPVDD25 pKa = 4.22LVCHH29 pKa = 5.44EE30 pKa = 4.22QLGEE34 pKa = 4.16SEE36 pKa = 5.31DD37 pKa = 4.4EE38 pKa = 3.96IDD40 pKa = 4.66EE41 pKa = 4.61PDD43 pKa = 3.34HH44 pKa = 6.8AVNHH48 pKa = 4.82QHH50 pKa = 6.25QLLARR55 pKa = 11.84RR56 pKa = 11.84DD57 pKa = 3.48EE58 pKa = 4.45PQRR61 pKa = 11.84HH62 pKa = 5.95TIQCSCCKK70 pKa = 10.36CNNTLQLVVEE80 pKa = 4.76ASRR83 pKa = 11.84DD84 pKa = 3.63TLRR87 pKa = 11.84QLQQLFMDD95 pKa = 4.27SLGFVCPWCATANQQ109 pKa = 3.65

Molecular weight:
12.5 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>sp|P24829|VE1_HPV39 Replication protein E1 OS=Human papillomavirus 39 OX=10588 GN=E1 PE=3 SV=1
MM1 pKa = 7.76AIWKK5 pKa = 7.87WKK7 pKa = 6.48QLKK10 pKa = 9.33WSTSDD15 pKa = 3.03GSVPTTEE22 pKa = 4.35LTTEE26 pKa = 4.63LSNTTATHH34 pKa = 5.33STATTPCTQKK44 pKa = 9.88TIPPPSRR51 pKa = 11.84KK52 pKa = 9.32RR53 pKa = 11.84PRR55 pKa = 11.84QCAVTEE61 pKa = 3.97PTEE64 pKa = 4.12PDD66 pKa = 4.07GVSLDD71 pKa = 3.77HH72 pKa = 6.99LNNPLHH78 pKa = 6.67SNSTGHH84 pKa = 4.91NTRR87 pKa = 11.84RR88 pKa = 11.84YY89 pKa = 8.91LSCGNTTPIIHH100 pKa = 7.1LKK102 pKa = 9.86GDD104 pKa = 3.68KK105 pKa = 10.75NGLKK109 pKa = 10.14CLRR112 pKa = 11.84YY113 pKa = 9.56RR114 pKa = 11.84LQKK117 pKa = 10.66YY118 pKa = 7.59DD119 pKa = 3.66TLFEE123 pKa = 5.07NISCTWHH130 pKa = 6.68WIRR133 pKa = 11.84GKK135 pKa = 8.24GTKK138 pKa = 9.47NAGILTVTYY147 pKa = 8.48ATEE150 pKa = 3.96SQRR153 pKa = 11.84QKK155 pKa = 11.07FLDD158 pKa = 3.7TVKK161 pKa = 10.22IPSSVHH167 pKa = 4.93VSLGYY172 pKa = 7.7MTLL175 pKa = 3.52

Molecular weight:
19.64 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

9

0

9

2597

72

647

288.6

32.44

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.468 ± 0.524

2.926 ± 0.706

5.93 ± 0.699

4.505 ± 0.551

3.466 ± 0.563

5.583 ± 0.707

2.349 ± 0.361

5.006 ± 0.405

5.044 ± 0.632

8.048 ± 0.807

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.041 ± 0.32

4.428 ± 0.397

6.007 ± 1.04

4.351 ± 0.558

5.16 ± 0.562

7.624 ± 0.932

9.665 ± 1.04

6.469 ± 0.545

1.656 ± 0.317

4.274 ± 0.476

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski