Macaca nemestrina (Pig-tailed macaque)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires;

Average proteome isoelectric point is 6.7

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 45002 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A2K6D1Z7|A0A2K6D1Z7_MACNE Neuronal PAS domain protein 1 OS=Macaca nemestrina OX=9545 GN=NPAS1 PE=4 SV=1
MM1 pKa = 8.28DD2 pKa = 4.65ILFAAILAVPLILGQEE18 pKa = 4.32YY19 pKa = 10.42EE20 pKa = 4.16DD21 pKa = 4.06EE22 pKa = 4.14EE23 pKa = 5.45RR24 pKa = 11.84MGEE27 pKa = 3.93DD28 pKa = 3.06EE29 pKa = 4.79YY30 pKa = 11.7YY31 pKa = 10.43QVVYY35 pKa = 10.06YY36 pKa = 7.57YY37 pKa = 10.19TVTPSYY43 pKa = 11.45DD44 pKa = 3.41DD45 pKa = 4.42FSADD49 pKa = 3.3FTIDD53 pKa = 3.3YY54 pKa = 10.76SIFEE58 pKa = 4.24SEE60 pKa = 4.57DD61 pKa = 3.04RR62 pKa = 11.84LNRR65 pKa = 11.84LDD67 pKa = 4.3KK68 pKa = 10.73DD69 pKa = 3.46TTEE72 pKa = 4.3AVGTTISLEE81 pKa = 4.2TARR84 pKa = 11.84ADD86 pKa = 3.33HH87 pKa = 6.74PKK89 pKa = 9.96PVTVKK94 pKa = 10.37PVTTEE99 pKa = 3.76PQSPDD104 pKa = 3.21LNDD107 pKa = 3.53AVSSLRR113 pKa = 11.84SPIPLLLSCAFVQAGMYY130 pKa = 9.95FMM132 pKa = 6.19

Molecular weight: 14.89 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A2K6ED53|A0A2K6ED53_MACNE Dynactin subunit 3 OS=Macaca nemestrina OX=9545 GN=DCTN3 PE=4 SV=1
MM1 pKa = 7.1RR2 pKa = 11.84AKK4 pKa = 9.12WRR6 pKa = 11.84KK7 pKa = 9.1KK8 pKa = 9.32RR9 pKa = 11.84MRR11 pKa = 11.84RR12 pKa = 11.84LKK14 pKa = 10.08RR15 pKa = 11.84KK16 pKa = 8.21RR17 pKa = 11.84RR18 pKa = 11.84KK19 pKa = 8.46MRR21 pKa = 11.84QRR23 pKa = 11.84SKK25 pKa = 11.41

Molecular weight: 3.46 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

21022

23980

45002

24382028

12

22498

541.8

60.44

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.892 ± 0.013

2.214 ± 0.01

4.859 ± 0.008

7.237 ± 0.013

3.609 ± 0.008

6.463 ± 0.016

2.6 ± 0.006

4.404 ± 0.01

5.866 ± 0.015

9.868 ± 0.016

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.165 ± 0.005

3.676 ± 0.009

6.183 ± 0.017

4.825 ± 0.011

5.647 ± 0.012

8.325 ± 0.017

5.327 ± 0.008

5.99 ± 0.009

1.199 ± 0.004

2.648 ± 0.007
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski