Amino acid dipepetide frequency for Flavihumibacter petaseus NBRC 106054

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.05AlaAla: 9.05 ± 0.115	0.778AlaCys: 0.778 ± 0.023	4.674AlaAsp: 4.674 ± 0.054	4.273AlaGlu: 4.273 ± 0.058	3.873AlaPhe: 3.873 ± 0.046	7.227AlaGly: 7.227 ± 0.075	1.33AlaHis: 1.33 ± 0.028	5.627AlaIle: 5.627 ± 0.076	3.942AlaLys: 3.942 ± 0.061	7.707AlaLeu: 7.707 ± 0.083	2.007AlaMet: 2.007 ± 0.033	3.428AlaAsn: 3.428 ± 0.056	3.094AlaPro: 3.094 ± 0.065	2.834AlaGln: 2.834 ± 0.046	3.393AlaArg: 3.393 ± 0.045	4.79AlaSer: 4.79 ± 0.054	4.77AlaThr: 4.77 ± 0.07	5.835AlaVal: 5.835 ± 0.078	1.169AlaTrp: 1.169 ± 0.028	2.921AlaTyr: 2.921 ± 0.044	0.0AlaXaa: 0.0 ± 0.0
Cys	0.641CysAla: 0.641 ± 0.047	0.156CysCys: 0.156 ± 0.01	0.368CysAsp: 0.368 ± 0.013	0.356CysGlu: 0.356 ± 0.017	0.462CysPhe: 0.462 ± 0.016	0.657CysGly: 0.657 ± 0.022	0.191CysHis: 0.191 ± 0.011	0.579CysIle: 0.579 ± 0.02	0.367CysLys: 0.367 ± 0.015	0.887CysLeu: 0.887 ± 0.025	0.216CysMet: 0.216 ± 0.011	0.374CysAsn: 0.374 ± 0.014	0.359CysPro: 0.359 ± 0.018	0.299CysGln: 0.299 ± 0.016	0.466CysArg: 0.466 ± 0.018	0.568CysSer: 0.568 ± 0.021	0.457CysThr: 0.457 ± 0.018	0.435CysVal: 0.435 ± 0.016	0.141CysTrp: 0.141 ± 0.01	0.343CysTyr: 0.343 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	4.429AspAla: 4.429 ± 0.056	0.41AspCys: 0.41 ± 0.015	2.512AspAsp: 2.512 ± 0.042	2.906AspGlu: 2.906 ± 0.049	2.8AspPhe: 2.8 ± 0.039	4.269AspGly: 4.269 ± 0.07	1.09AspHis: 1.09 ± 0.03	3.55AspIle: 3.55 ± 0.046	3.186AspLys: 3.186 ± 0.048	5.033AspLeu: 5.033 ± 0.061	1.152AspMet: 1.152 ± 0.026	2.645AspAsn: 2.645 ± 0.047	2.644AspPro: 2.644 ± 0.043	2.057AspGln: 2.057 ± 0.035	2.641AspArg: 2.641 ± 0.044	3.175AspSer: 3.175 ± 0.058	2.677AspThr: 2.677 ± 0.035	2.993AspVal: 2.993 ± 0.048	0.928AspTrp: 0.928 ± 0.024	2.308AspTyr: 2.308 ± 0.042	0.0AspXaa: 0.0 ± 0.0
Glu	4.575GluAla: 4.575 ± 0.064	0.348GluCys: 0.348 ± 0.015	2.485GluAsp: 2.485 ± 0.044	3.253GluGlu: 3.253 ± 0.057	2.129GluPhe: 2.129 ± 0.034	3.69GluGly: 3.69 ± 0.047	1.047GluHis: 1.047 ± 0.024	3.666GluIle: 3.666 ± 0.054	4.661GluLys: 4.661 ± 0.063	5.193GluLeu: 5.193 ± 0.057	1.536GluMet: 1.536 ± 0.034	2.796GluAsn: 2.796 ± 0.045	1.877GluPro: 1.877 ± 0.035	2.432GluGln: 2.432 ± 0.047	2.483GluArg: 2.483 ± 0.04	2.857GluSer: 2.857 ± 0.042	3.056GluThr: 3.056 ± 0.043	3.382GluVal: 3.382 ± 0.045	0.84GluTrp: 0.84 ± 0.024	1.866GluTyr: 1.866 ± 0.031	0.0GluXaa: 0.0 ± 0.0
Phe	3.447PheAla: 3.447 ± 0.045	0.466PheCys: 0.466 ± 0.022	2.856PheAsp: 2.856 ± 0.038	2.444PheGlu: 2.444 ± 0.041	2.319PhePhe: 2.319 ± 0.045	3.497PheGly: 3.497 ± 0.052	0.97PheHis: 0.97 ± 0.024	2.759PheIle: 2.759 ± 0.042	2.087PheLys: 2.087 ± 0.036	4.501PheLeu: 4.501 ± 0.058	1.007PheMet: 1.007 ± 0.026	2.543PheAsn: 2.543 ± 0.038	2.032PhePro: 2.032 ± 0.034	1.605PheGln: 1.605 ± 0.036	2.851PheArg: 2.851 ± 0.044	3.606PheSer: 3.606 ± 0.048	3.172PheThr: 3.172 ± 0.056	2.768PheVal: 2.768 ± 0.048	0.698PheTrp: 0.698 ± 0.023	1.798PheTyr: 1.798 ± 0.036	0.0PheXaa: 0.0 ± 0.0
Gly	5.172GlyAla: 5.172 ± 0.063	0.716GlyCys: 0.716 ± 0.026	3.868GlyAsp: 3.868 ± 0.061	3.697GlyGlu: 3.697 ± 0.046	3.751GlyPhe: 3.751 ± 0.054	5.606GlyGly: 5.606 ± 0.105	1.335GlyHis: 1.335 ± 0.03	5.441GlyIle: 5.441 ± 0.062	5.494GlyLys: 5.494 ± 0.063	6.444GlyLeu: 6.444 ± 0.068	1.937GlyMet: 1.937 ± 0.036	4.189GlyAsn: 4.189 ± 0.058	1.979GlyPro: 1.979 ± 0.039	2.612GlyGln: 2.612 ± 0.049	3.352GlyArg: 3.352 ± 0.054	4.827GlySer: 4.827 ± 0.077	4.645GlyThr: 4.645 ± 0.097	4.717GlyVal: 4.717 ± 0.061	1.319GlyTrp: 1.319 ± 0.029	3.341GlyTyr: 3.341 ± 0.053	0.0GlyXaa: 0.0 ± 0.0
His	1.394HisAla: 1.394 ± 0.033	0.203HisCys: 0.203 ± 0.012	0.952HisAsp: 0.952 ± 0.025	0.99HisGlu: 0.99 ± 0.025	1.23HisPhe: 1.23 ± 0.029	1.27HisGly: 1.27 ± 0.032	0.631HisHis: 0.631 ± 0.021	1.214HisIle: 1.214 ± 0.026	0.79HisLys: 0.79 ± 0.021	1.978HisLeu: 1.978 ± 0.039	0.394HisMet: 0.394 ± 0.016	0.777HisAsn: 0.777 ± 0.02	1.244HisPro: 1.244 ± 0.029	0.912HisGln: 0.912 ± 0.025	1.005HisArg: 1.005 ± 0.026	1.079HisSer: 1.079 ± 0.022	0.975HisThr: 0.975 ± 0.022	0.969HisVal: 0.969 ± 0.019	0.331HisTrp: 0.331 ± 0.016	0.948HisTyr: 0.948 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	5.518IleAla: 5.518 ± 0.064	0.662IleCys: 0.662 ± 0.023	3.769IleAsp: 3.769 ± 0.052	3.27IleGlu: 3.27 ± 0.049	2.731IlePhe: 2.731 ± 0.047	4.661IleGly: 4.661 ± 0.058	1.226IleHis: 1.226 ± 0.023	3.7IleIle: 3.7 ± 0.048	2.96IleLys: 2.96 ± 0.051	5.6IleLeu: 5.6 ± 0.063	1.173IleMet: 1.173 ± 0.027	3.316IleAsn: 3.316 ± 0.059	3.233IlePro: 3.233 ± 0.048	2.157IleGln: 2.157 ± 0.036	4.0IleArg: 4.0 ± 0.05	4.546IleSer: 4.546 ± 0.058	4.235IleThr: 4.235 ± 0.069	3.865IleVal: 3.865 ± 0.048	0.743IleTrp: 0.743 ± 0.024	2.157IleTyr: 2.157 ± 0.031	0.0IleXaa: 0.0 ± 0.0
Lys	4.86LysAla: 4.86 ± 0.06	0.278LysCys: 0.278 ± 0.014	3.363LysAsp: 3.363 ± 0.05	3.733LysGlu: 3.733 ± 0.054	2.086LysPhe: 2.086 ± 0.034	4.321LysGly: 4.321 ± 0.059	1.007LysHis: 1.007 ± 0.029	3.499LysIle: 3.499 ± 0.049	4.268LysLys: 4.268 ± 0.067	5.005LysLeu: 5.005 ± 0.06	1.627LysMet: 1.627 ± 0.031	2.729LysAsn: 2.729 ± 0.044	2.437LysPro: 2.437 ± 0.041	2.348LysGln: 2.348 ± 0.047	2.387LysArg: 2.387 ± 0.032	3.313LysSer: 3.313 ± 0.043	3.411LysThr: 3.411 ± 0.044	3.709LysVal: 3.709 ± 0.053	0.794LysTrp: 0.794 ± 0.023	2.042LysTyr: 2.042 ± 0.043	0.0LysXaa: 0.0 ± 0.0
Leu	7.539LeuAla: 7.539 ± 0.081	0.829LeuCys: 0.829 ± 0.025	4.714LeuAsp: 4.714 ± 0.053	5.284LeuGlu: 5.284 ± 0.078	4.503LeuPhe: 4.503 ± 0.061	5.896LeuGly: 5.896 ± 0.071	1.985LeuHis: 1.985 ± 0.041	5.426LeuIle: 5.426 ± 0.064	5.596LeuLys: 5.596 ± 0.066	10.541LeuLeu: 10.541 ± 0.112	2.139LeuMet: 2.139 ± 0.042	4.617LeuAsn: 4.617 ± 0.06	4.982LeuPro: 4.982 ± 0.06	4.642LeuGln: 4.642 ± 0.061	4.68LeuArg: 4.68 ± 0.061	6.578LeuSer: 6.578 ± 0.068	5.431LeuThr: 5.431 ± 0.055	6.275LeuVal: 6.275 ± 0.066	1.049LeuTrp: 1.049 ± 0.028	3.347LeuTyr: 3.347 ± 0.057	0.0LeuXaa: 0.0 ± 0.0
Met	2.055MetAla: 2.055 ± 0.038	0.127MetCys: 0.127 ± 0.007	1.252MetAsp: 1.252 ± 0.03	1.482MetGlu: 1.482 ± 0.032	0.758MetPhe: 0.758 ± 0.023	1.674MetGly: 1.674 ± 0.035	0.476MetHis: 0.476 ± 0.016	1.497MetIle: 1.497 ± 0.037	1.758MetLys: 1.758 ± 0.035	2.25MetLeu: 2.25 ± 0.043	0.653MetMet: 0.653 ± 0.021	1.166MetAsn: 1.166 ± 0.025	1.214MetPro: 1.214 ± 0.027	1.019MetGln: 1.019 ± 0.025	1.12MetArg: 1.12 ± 0.025	1.249MetSer: 1.249 ± 0.03	1.313MetThr: 1.313 ± 0.027	1.528MetVal: 1.528 ± 0.032	0.201MetTrp: 0.201 ± 0.011	0.613MetTyr: 0.613 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.848AsnAla: 3.848 ± 0.053	0.4AsnCys: 0.4 ± 0.015	2.609AsnAsp: 2.609 ± 0.046	2.451AsnGlu: 2.451 ± 0.039	2.196AsnPhe: 2.196 ± 0.04	4.33AsnGly: 4.33 ± 0.081	0.895AsnHis: 0.895 ± 0.025	3.231AsnIle: 3.231 ± 0.047	2.497AsnLys: 2.497 ± 0.04	4.351AsnLeu: 4.351 ± 0.06	1.071AsnMet: 1.071 ± 0.024	2.805AsnAsn: 2.805 ± 0.058	2.507AsnPro: 2.507 ± 0.046	1.858AsnGln: 1.858 ± 0.035	2.596AsnArg: 2.596 ± 0.041	2.994AsnSer: 2.994 ± 0.05	3.036AsnThr: 3.036 ± 0.065	2.633AsnVal: 2.633 ± 0.048	0.764AsnTrp: 0.764 ± 0.02	2.095AsnTyr: 2.095 ± 0.044	0.0AsnXaa: 0.0 ± 0.0
Pro	4.784ProAla: 4.784 ± 0.127	0.239ProCys: 0.239 ± 0.011	3.131ProAsp: 3.131 ± 0.047	3.143ProGlu: 3.143 ± 0.044	2.1ProPhe: 2.1 ± 0.033	3.805ProGly: 3.805 ± 0.052	0.768ProHis: 0.768 ± 0.022	2.134ProIle: 2.134 ± 0.036	1.761ProLys: 1.761 ± 0.035	3.866ProLeu: 3.866 ± 0.046	0.904ProMet: 0.904 ± 0.025	1.761ProAsn: 1.761 ± 0.039	1.48ProPro: 1.48 ± 0.036	1.497ProGln: 1.497 ± 0.027	1.512ProArg: 1.512 ± 0.03	2.398ProSer: 2.398 ± 0.036	2.054ProThr: 2.054 ± 0.058	4.254ProVal: 4.254 ± 0.063	0.597ProTrp: 0.597 ± 0.021	1.622ProTyr: 1.622 ± 0.037	0.0ProXaa: 0.0 ± 0.0
Gln	3.015GlnAla: 3.015 ± 0.045	0.276GlnCys: 0.276 ± 0.026	1.685GlnAsp: 1.685 ± 0.031	2.28GlnGlu: 2.28 ± 0.041	1.915GlnPhe: 1.915 ± 0.038	2.207GlnGly: 2.207 ± 0.042	0.969GlnHis: 0.969 ± 0.026	2.051GlnIle: 2.051 ± 0.037	2.21GlnLys: 2.21 ± 0.036	4.73GlnLeu: 4.73 ± 0.071	0.979GlnMet: 0.979 ± 0.024	1.52GlnAsn: 1.52 ± 0.03	2.103GlnPro: 2.103 ± 0.033	2.69GlnGln: 2.69 ± 0.048	1.858GlnArg: 1.858 ± 0.032	2.163GlnSer: 2.163 ± 0.036	2.057GlnThr: 2.057 ± 0.034	2.793GlnVal: 2.793 ± 0.045	0.637GlnTrp: 0.637 ± 0.019	1.801GlnTyr: 1.801 ± 0.035	0.0GlnXaa: 0.0 ± 0.0
Arg	2.978ArgAla: 2.978 ± 0.043	0.307ArgCys: 0.307 ± 0.013	2.478ArgAsp: 2.478 ± 0.038	3.03ArgGlu: 3.03 ± 0.053	2.635ArgPhe: 2.635 ± 0.044	2.58ArgGly: 2.58 ± 0.043	0.981ArgHis: 0.981 ± 0.028	3.59ArgIle: 3.59 ± 0.047	3.412ArgLys: 3.412 ± 0.047	4.74ArgLeu: 4.74 ± 0.062	1.355ArgMet: 1.355 ± 0.03	2.803ArgAsn: 2.803 ± 0.039	1.881ArgPro: 1.881 ± 0.037	2.413ArgGln: 2.413 ± 0.04	2.285ArgArg: 2.285 ± 0.041	2.721ArgSer: 2.721 ± 0.042	2.371ArgThr: 2.371 ± 0.035	2.734ArgVal: 2.734 ± 0.041	0.798ArgTrp: 0.798 ± 0.02	2.269ArgTyr: 2.269 ± 0.04	0.0ArgXaa: 0.0 ± 0.0
Ser	4.904SerAla: 4.904 ± 0.064	0.614SerCys: 0.614 ± 0.021	3.04SerAsp: 3.04 ± 0.048	2.753SerGlu: 2.753 ± 0.044	3.396SerPhe: 3.396 ± 0.047	5.669SerGly: 5.669 ± 0.091	1.096SerHis: 1.096 ± 0.028	4.1SerIle: 4.1 ± 0.052	3.006SerLys: 3.006 ± 0.042	6.327SerLeu: 6.327 ± 0.068	1.406SerMet: 1.406 ± 0.028	2.889SerAsn: 2.889 ± 0.051	2.663SerPro: 2.663 ± 0.045	2.078SerGln: 2.078 ± 0.037	3.216SerArg: 3.216 ± 0.041	3.779SerSer: 3.779 ± 0.067	3.447SerThr: 3.447 ± 0.055	4.159SerVal: 4.159 ± 0.06	0.991SerTrp: 0.991 ± 0.027	2.382SerTyr: 2.382 ± 0.043	0.0SerXaa: 0.0 ± 0.0
Thr	5.499ThrAla: 5.499 ± 0.069	0.448ThrCys: 0.448 ± 0.015	3.293ThrAsp: 3.293 ± 0.049	2.831ThrGlu: 2.831 ± 0.044	2.556ThrPhe: 2.556 ± 0.077	5.423ThrGly: 5.423 ± 0.064	0.951ThrHis: 0.951 ± 0.022	4.16ThrIle: 4.16 ± 0.063	2.373ThrLys: 2.373 ± 0.046	5.338ThrLeu: 5.338 ± 0.068	1.068ThrMet: 1.068 ± 0.025	2.518ThrAsn: 2.518 ± 0.047	2.884ThrPro: 2.884 ± 0.091	1.705ThrGln: 1.705 ± 0.028	2.569ThrArg: 2.569 ± 0.042	3.447ThrSer: 3.447 ± 0.07	3.728ThrThr: 3.728 ± 0.105	4.317ThrVal: 4.317 ± 0.078	0.975ThrTrp: 0.975 ± 0.038	2.257ThrTyr: 2.257 ± 0.051	0.0ThrXaa: 0.0 ± 0.0
Val	5.197ValAla: 5.197 ± 0.069	0.564ValCys: 0.564 ± 0.018	3.358ValAsp: 3.358 ± 0.042	3.289ValGlu: 3.289 ± 0.048	3.133ValPhe: 3.133 ± 0.045	3.742ValGly: 3.742 ± 0.048	1.162ValHis: 1.162 ± 0.026	4.402ValIle: 4.402 ± 0.058	3.889ValLys: 3.889 ± 0.053	6.299ValLeu: 6.299 ± 0.067	1.556ValMet: 1.556 ± 0.028	3.491ValAsn: 3.491 ± 0.062	2.939ValPro: 2.939 ± 0.048	2.32ValGln: 2.32 ± 0.042	2.984ValArg: 2.984 ± 0.046	4.399ValSer: 4.399 ± 0.058	4.37ValThr: 4.37 ± 0.086	4.511ValVal: 4.511 ± 0.053	0.798ValTrp: 0.798 ± 0.022	2.407ValTyr: 2.407 ± 0.036	0.0ValXaa: 0.0 ± 0.0
Trp	0.875TrpAla: 0.875 ± 0.024	0.127TrpCys: 0.127 ± 0.008	0.738TrpAsp: 0.738 ± 0.027	0.816TrpGlu: 0.816 ± 0.022	0.715TrpPhe: 0.715 ± 0.019	0.99TrpGly: 0.99 ± 0.029	0.309TrpHis: 0.309 ± 0.013	0.869TrpIle: 0.869 ± 0.026	1.072TrpLys: 1.072 ± 0.028	1.573TrpLeu: 1.573 ± 0.035	0.473TrpMet: 0.473 ± 0.018	0.757TrpAsn: 0.757 ± 0.023	0.454TrpPro: 0.454 ± 0.017	0.727TrpGln: 0.727 ± 0.022	0.683TrpArg: 0.683 ± 0.018	0.909TrpSer: 0.909 ± 0.034	0.808TrpThr: 0.808 ± 0.025	0.876TrpVal: 0.876 ± 0.024	0.304TrpTrp: 0.304 ± 0.013	0.604TrpTyr: 0.604 ± 0.023	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.941TyrAla: 2.941 ± 0.047	0.374TyrCys: 0.374 ± 0.016	2.258TyrAsp: 2.258 ± 0.038	1.891TyrGlu: 1.891 ± 0.034	2.135TyrPhe: 2.135 ± 0.037	2.929TyrGly: 2.929 ± 0.054	0.867TyrHis: 0.867 ± 0.023	2.028TyrIle: 2.028 ± 0.041	1.89TyrLys: 1.89 ± 0.037	3.69TyrLeu: 3.69 ± 0.049	0.753TyrMet: 0.753 ± 0.021	2.041TyrAsn: 2.041 ± 0.042	1.804TyrPro: 1.804 ± 0.033	1.734TyrGln: 1.734 ± 0.028	2.28TyrArg: 2.28 ± 0.04	2.518TyrSer: 2.518 ± 0.053	2.327TyrThr: 2.327 ± 0.057	2.06TyrVal: 2.06 ± 0.039	0.6TyrTrp: 0.6 ± 0.018	1.886TyrTyr: 1.886 ± 0.042	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4759 proteins (1741998 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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