Amino acid dipepetide frequency for Mycobacterium phage L5 (Mycobacteriophage L5)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.352AlaAla: 10.352 ± 0.989
0.757AlaCys: 0.757 ± 0.272
5.744AlaAsp: 5.744 ± 0.604
7.954AlaGlu: 7.954 ± 0.776
3.598AlaPhe: 3.598 ± 0.518
7.512AlaGly: 7.512 ± 0.823
1.452AlaHis: 1.452 ± 0.323
4.734AlaIle: 4.734 ± 0.416
5.239AlaLys: 5.239 ± 0.527
8.648AlaLeu: 8.648 ± 0.961
2.777AlaMet: 2.777 ± 0.345
2.904AlaAsn: 2.904 ± 0.446
4.797AlaPro: 4.797 ± 0.638
3.472AlaGln: 3.472 ± 0.505
5.555AlaArg: 5.555 ± 0.558
4.671AlaSer: 4.671 ± 0.449
5.176AlaThr: 5.176 ± 0.582
6.565AlaVal: 6.565 ± 0.537
2.146AlaTrp: 2.146 ± 0.369
2.714AlaTyr: 2.714 ± 0.492
0.0AlaXaa: 0.0 ± 0.0
Cys
0.631CysAla: 0.631 ± 0.221
0.189CysCys: 0.189 ± 0.128
0.884CysAsp: 0.884 ± 0.264
0.631CysGlu: 0.631 ± 0.195
0.316CysPhe: 0.316 ± 0.162
0.947CysGly: 0.947 ± 0.272
0.252CysHis: 0.252 ± 0.146
0.252CysIle: 0.252 ± 0.13
0.568CysLys: 0.568 ± 0.167
0.821CysLeu: 0.821 ± 0.267
0.252CysMet: 0.252 ± 0.138
0.379CysAsn: 0.379 ± 0.127
0.631CysPro: 0.631 ± 0.22
0.316CysGln: 0.316 ± 0.133
0.568CysArg: 0.568 ± 0.194
0.379CysSer: 0.379 ± 0.212
0.631CysThr: 0.631 ± 0.193
0.568CysVal: 0.568 ± 0.209
0.316CysTrp: 0.316 ± 0.166
0.316CysTyr: 0.316 ± 0.143
0.0CysXaa: 0.0 ± 0.0
Asp
5.492AspAla: 5.492 ± 0.698
0.947AspCys: 0.947 ± 0.295
4.292AspAsp: 4.292 ± 0.691
4.86AspGlu: 4.86 ± 0.598
2.399AspPhe: 2.399 ± 0.496
5.744AspGly: 5.744 ± 0.611
1.641AspHis: 1.641 ± 0.407
3.409AspIle: 3.409 ± 0.419
2.841AspLys: 2.841 ± 0.41
5.429AspLeu: 5.429 ± 0.574
1.262AspMet: 1.262 ± 0.277
1.578AspAsn: 1.578 ± 0.384
4.356AspPro: 4.356 ± 0.547
2.272AspGln: 2.272 ± 0.422
3.661AspArg: 3.661 ± 0.5
2.714AspSer: 2.714 ± 0.489
3.219AspThr: 3.219 ± 0.477
4.482AspVal: 4.482 ± 0.469
1.389AspTrp: 1.389 ± 0.279
2.462AspTyr: 2.462 ± 0.393
0.0AspXaa: 0.0 ± 0.0
Glu
6.944GluAla: 6.944 ± 0.907
0.316GluCys: 0.316 ± 0.127
4.734GluAsp: 4.734 ± 0.596
5.176GluGlu: 5.176 ± 0.693
3.093GluPhe: 3.093 ± 0.422
4.987GluGly: 4.987 ± 0.661
1.262GluHis: 1.262 ± 0.301
3.724GluIle: 3.724 ± 0.467
2.525GluLys: 2.525 ± 0.378
7.701GluLeu: 7.701 ± 0.677
2.462GluMet: 2.462 ± 0.421
2.399GluAsn: 2.399 ± 0.357
2.525GluPro: 2.525 ± 0.41
1.578GluGln: 1.578 ± 0.306
4.987GluArg: 4.987 ± 0.551
2.651GluSer: 2.651 ± 0.432
3.787GluThr: 3.787 ± 0.493
5.492GluVal: 5.492 ± 0.67
1.389GluTrp: 1.389 ± 0.302
2.588GluTyr: 2.588 ± 0.361
0.0GluXaa: 0.0 ± 0.0
Phe
3.409PheAla: 3.409 ± 0.472
0.252PheCys: 0.252 ± 0.135
2.272PheAsp: 2.272 ± 0.403
3.03PheGlu: 3.03 ± 0.395
0.694PhePhe: 0.694 ± 0.26
2.714PheGly: 2.714 ± 0.414
0.884PheHis: 0.884 ± 0.261
1.515PheIle: 1.515 ± 0.394
1.452PheLys: 1.452 ± 0.29
2.336PheLeu: 2.336 ± 0.348
0.568PheMet: 0.568 ± 0.205
1.262PheAsn: 1.262 ± 0.299
2.083PhePro: 2.083 ± 0.373
1.452PheGln: 1.452 ± 0.314
2.462PheArg: 2.462 ± 0.375
1.894PheSer: 1.894 ± 0.391
2.336PheThr: 2.336 ± 0.322
2.02PheVal: 2.02 ± 0.378
0.568PheTrp: 0.568 ± 0.224
0.631PheTyr: 0.631 ± 0.205
0.0PheXaa: 0.0 ± 0.0
Gly
6.754GlyAla: 6.754 ± 0.759
0.884GlyCys: 0.884 ± 0.265
5.492GlyAsp: 5.492 ± 0.595
4.482GlyGlu: 4.482 ± 0.589
2.904GlyPhe: 2.904 ± 0.419
7.954GlyGly: 7.954 ± 1.224
1.894GlyHis: 1.894 ± 0.316
4.04GlyIle: 4.04 ± 0.523
3.787GlyLys: 3.787 ± 0.573
6.502GlyLeu: 6.502 ± 0.916
1.957GlyMet: 1.957 ± 0.355
3.346GlyAsn: 3.346 ± 0.37
3.156GlyPro: 3.156 ± 0.333
3.093GlyGln: 3.093 ± 0.431
4.356GlyArg: 4.356 ± 0.444
3.219GlySer: 3.219 ± 0.382
5.176GlyThr: 5.176 ± 0.726
5.807GlyVal: 5.807 ± 0.663
1.704GlyTrp: 1.704 ± 0.343
2.588GlyTyr: 2.588 ± 0.418
0.0GlyXaa: 0.0 ± 0.0
His
1.578HisAla: 1.578 ± 0.369
0.379HisCys: 0.379 ± 0.145
1.767HisAsp: 1.767 ± 0.357
1.641HisGlu: 1.641 ± 0.445
0.442HisPhe: 0.442 ± 0.173
1.578HisGly: 1.578 ± 0.389
0.631HisHis: 0.631 ± 0.205
1.452HisIle: 1.452 ± 0.422
1.073HisLys: 1.073 ± 0.271
1.767HisLeu: 1.767 ± 0.323
0.379HisMet: 0.379 ± 0.134
0.379HisAsn: 0.379 ± 0.14
1.389HisPro: 1.389 ± 0.259
0.947HisGln: 0.947 ± 0.191
1.831HisArg: 1.831 ± 0.444
0.821HisSer: 0.821 ± 0.226
1.515HisThr: 1.515 ± 0.39
1.578HisVal: 1.578 ± 0.261
0.379HisTrp: 0.379 ± 0.165
0.884HisTyr: 0.884 ± 0.334
0.0HisXaa: 0.0 ± 0.0
Ile
5.176IleAla: 5.176 ± 0.526
0.505IleCys: 0.505 ± 0.215
3.598IleAsp: 3.598 ± 0.429
4.356IleGlu: 4.356 ± 0.474
1.199IlePhe: 1.199 ± 0.266
3.598IleGly: 3.598 ± 0.658
1.389IleHis: 1.389 ± 0.42
1.831IleIle: 1.831 ± 0.347
2.967IleLys: 2.967 ± 0.477
4.103IleLeu: 4.103 ± 0.537
0.694IleMet: 0.694 ± 0.189
1.957IleAsn: 1.957 ± 0.368
3.472IlePro: 3.472 ± 0.391
1.831IleGln: 1.831 ± 0.385
2.841IleArg: 2.841 ± 0.416
2.399IleSer: 2.399 ± 0.444
3.03IleThr: 3.03 ± 0.388
3.093IleVal: 3.093 ± 0.354
0.631IleTrp: 0.631 ± 0.177
1.073IleTyr: 1.073 ± 0.269
0.0IleXaa: 0.0 ± 0.0
Lys
5.176LysAla: 5.176 ± 0.57
0.252LysCys: 0.252 ± 0.146
3.409LysAsp: 3.409 ± 0.497
2.083LysGlu: 2.083 ± 0.325
1.326LysPhe: 1.326 ± 0.273
3.282LysGly: 3.282 ± 0.499
0.884LysHis: 0.884 ± 0.217
2.336LysIle: 2.336 ± 0.409
3.724LysLys: 3.724 ± 0.551
3.724LysLeu: 3.724 ± 0.492
1.389LysMet: 1.389 ± 0.31
1.262LysAsn: 1.262 ± 0.317
3.598LysPro: 3.598 ± 0.564
1.578LysGln: 1.578 ± 0.329
3.787LysArg: 3.787 ± 0.604
2.083LysSer: 2.083 ± 0.381
3.093LysThr: 3.093 ± 0.48
4.86LysVal: 4.86 ± 0.554
0.947LysTrp: 0.947 ± 0.235
1.136LysTyr: 1.136 ± 0.335
0.0LysXaa: 0.0 ± 0.0
Leu
8.522LeuAla: 8.522 ± 0.874
0.694LeuCys: 0.694 ± 0.234
4.545LeuAsp: 4.545 ± 0.468
5.807LeuGlu: 5.807 ± 0.564
2.777LeuPhe: 2.777 ± 0.401
6.754LeuGly: 6.754 ± 0.942
2.272LeuHis: 2.272 ± 0.472
4.292LeuIle: 4.292 ± 0.461
3.346LeuLys: 3.346 ± 0.357
5.302LeuLeu: 5.302 ± 0.495
2.588LeuMet: 2.588 ± 0.428
2.777LeuAsn: 2.777 ± 0.435
4.482LeuPro: 4.482 ± 0.466
3.093LeuGln: 3.093 ± 0.746
4.987LeuArg: 4.987 ± 0.726
5.618LeuSer: 5.618 ± 0.59
4.545LeuThr: 4.545 ± 0.628
5.05LeuVal: 5.05 ± 0.693
1.515LeuTrp: 1.515 ± 0.323
2.462LeuTyr: 2.462 ± 0.422
0.0LeuXaa: 0.0 ± 0.0
Met
2.777MetAla: 2.777 ± 0.422
0.189MetCys: 0.189 ± 0.11
1.01MetAsp: 1.01 ± 0.239
1.704MetGlu: 1.704 ± 0.305
0.316MetPhe: 0.316 ± 0.135
1.452MetGly: 1.452 ± 0.341
0.505MetHis: 0.505 ± 0.183
1.515MetIle: 1.515 ± 0.316
1.767MetLys: 1.767 ± 0.401
1.262MetLeu: 1.262 ± 0.29
0.505MetMet: 0.505 ± 0.16
0.694MetAsn: 0.694 ± 0.212
1.831MetPro: 1.831 ± 0.31
0.947MetGln: 0.947 ± 0.25
1.578MetArg: 1.578 ± 0.354
2.02MetSer: 2.02 ± 0.268
2.777MetThr: 2.777 ± 0.384
1.389MetVal: 1.389 ± 0.277
0.379MetTrp: 0.379 ± 0.142
0.442MetTyr: 0.442 ± 0.173
0.0MetXaa: 0.0 ± 0.0
Asn
3.282AsnAla: 3.282 ± 0.583
0.442AsnCys: 0.442 ± 0.166
1.831AsnAsp: 1.831 ± 0.378
1.894AsnGlu: 1.894 ± 0.364
0.884AsnPhe: 0.884 ± 0.31
3.156AsnGly: 3.156 ± 0.516
1.073AsnHis: 1.073 ± 0.289
1.326AsnIle: 1.326 ± 0.335
1.199AsnLys: 1.199 ± 0.33
2.841AsnLeu: 2.841 ± 0.445
0.947AsnMet: 0.947 ± 0.211
0.757AsnAsn: 0.757 ± 0.237
2.399AsnPro: 2.399 ± 0.39
1.326AsnGln: 1.326 ± 0.311
2.588AsnArg: 2.588 ± 0.483
1.578AsnSer: 1.578 ± 0.265
1.767AsnThr: 1.767 ± 0.326
2.588AsnVal: 2.588 ± 0.386
0.631AsnTrp: 0.631 ± 0.184
1.01AsnTyr: 1.01 ± 0.207
0.0AsnXaa: 0.0 ± 0.0
Pro
4.356ProAla: 4.356 ± 0.425
0.379ProCys: 0.379 ± 0.17
3.914ProAsp: 3.914 ± 0.528
4.229ProGlu: 4.229 ± 0.537
1.957ProPhe: 1.957 ± 0.351
4.229ProGly: 4.229 ± 0.58
1.136ProHis: 1.136 ± 0.26
2.904ProIle: 2.904 ± 0.362
2.336ProLys: 2.336 ± 0.487
3.346ProLeu: 3.346 ± 0.404
1.326ProMet: 1.326 ± 0.291
2.02ProAsn: 2.02 ± 0.334
2.588ProPro: 2.588 ± 0.548
1.957ProGln: 1.957 ± 0.397
3.472ProArg: 3.472 ± 0.61
2.777ProSer: 2.777 ± 0.438
3.409ProThr: 3.409 ± 0.425
4.292ProVal: 4.292 ± 0.538
1.136ProTrp: 1.136 ± 0.438
1.578ProTyr: 1.578 ± 0.329
0.0ProXaa: 0.0 ± 0.0
Gln
4.419GlnAla: 4.419 ± 0.717
0.316GlnCys: 0.316 ± 0.124
1.704GlnAsp: 1.704 ± 0.436
1.894GlnGlu: 1.894 ± 0.398
1.326GlnPhe: 1.326 ± 0.293
2.651GlnGly: 2.651 ± 0.369
0.884GlnHis: 0.884 ± 0.208
2.146GlnIle: 2.146 ± 0.351
1.894GlnLys: 1.894 ± 0.384
3.724GlnLeu: 3.724 ± 0.488
0.947GlnMet: 0.947 ± 0.276
1.389GlnAsn: 1.389 ± 0.311
1.262GlnPro: 1.262 ± 0.293
1.704GlnGln: 1.704 ± 0.401
2.272GlnArg: 2.272 ± 0.367
1.389GlnSer: 1.389 ± 0.324
1.704GlnThr: 1.704 ± 0.434
2.399GlnVal: 2.399 ± 0.343
0.821GlnTrp: 0.821 ± 0.235
1.01GlnTyr: 1.01 ± 0.223
0.0GlnXaa: 0.0 ± 0.0
Arg
5.744ArgAla: 5.744 ± 0.616
1.01ArgCys: 1.01 ± 0.302
4.356ArgAsp: 4.356 ± 0.599
4.797ArgGlu: 4.797 ± 0.648
2.399ArgPhe: 2.399 ± 0.52
3.787ArgGly: 3.787 ± 0.503
1.389ArgHis: 1.389 ± 0.307
4.229ArgIle: 4.229 ± 0.55
3.724ArgLys: 3.724 ± 0.531
5.681ArgLeu: 5.681 ± 0.541
1.704ArgMet: 1.704 ± 0.275
2.209ArgAsn: 2.209 ± 0.339
2.588ArgPro: 2.588 ± 0.362
2.02ArgGln: 2.02 ± 0.361
5.429ArgArg: 5.429 ± 0.558
2.714ArgSer: 2.714 ± 0.436
2.651ArgThr: 2.651 ± 0.373
4.356ArgVal: 4.356 ± 0.54
1.326ArgTrp: 1.326 ± 0.31
2.336ArgTyr: 2.336 ± 0.442
0.0ArgXaa: 0.0 ± 0.0
Ser
4.987SerAla: 4.987 ± 0.568
0.505SerCys: 0.505 ± 0.196
2.967SerAsp: 2.967 ± 0.337
3.409SerGlu: 3.409 ± 0.538
1.957SerPhe: 1.957 ± 0.377
4.482SerGly: 4.482 ± 0.606
1.01SerHis: 1.01 ± 0.242
2.083SerIle: 2.083 ± 0.343
2.714SerLys: 2.714 ± 0.408
3.851SerLeu: 3.851 ± 0.653
1.073SerMet: 1.073 ± 0.203
1.389SerAsn: 1.389 ± 0.276
2.904SerPro: 2.904 ± 0.414
1.641SerGln: 1.641 ± 0.288
3.535SerArg: 3.535 ± 0.459
2.525SerSer: 2.525 ± 0.454
2.904SerThr: 2.904 ± 0.407
3.472SerVal: 3.472 ± 0.487
1.262SerTrp: 1.262 ± 0.286
0.947SerTyr: 0.947 ± 0.206
0.0SerXaa: 0.0 ± 0.0
Thr
6.375ThrAla: 6.375 ± 0.698
0.694ThrCys: 0.694 ± 0.239
3.598ThrAsp: 3.598 ± 0.497
3.282ThrGlu: 3.282 ± 0.446
2.399ThrPhe: 2.399 ± 0.343
4.797ThrGly: 4.797 ± 0.642
1.262ThrHis: 1.262 ± 0.277
2.399ThrIle: 2.399 ± 0.423
3.346ThrLys: 3.346 ± 0.458
4.86ThrLeu: 4.86 ± 0.634
1.452ThrMet: 1.452 ± 0.261
1.957ThrAsn: 1.957 ± 0.337
3.598ThrPro: 3.598 ± 0.509
2.209ThrGln: 2.209 ± 0.382
3.156ThrArg: 3.156 ± 0.534
2.651ThrSer: 2.651 ± 0.474
2.462ThrThr: 2.462 ± 0.459
5.05ThrVal: 5.05 ± 0.497
1.136ThrTrp: 1.136 ± 0.284
1.894ThrTyr: 1.894 ± 0.298
0.0ThrXaa: 0.0 ± 0.0
Val
6.439ValAla: 6.439 ± 0.86
0.757ValCys: 0.757 ± 0.219
4.671ValAsp: 4.671 ± 0.548
5.618ValGlu: 5.618 ± 0.606
2.272ValPhe: 2.272 ± 0.386
5.239ValGly: 5.239 ± 0.614
1.767ValHis: 1.767 ± 0.325
3.03ValIle: 3.03 ± 0.409
3.472ValLys: 3.472 ± 0.435
5.492ValLeu: 5.492 ± 0.624
1.452ValMet: 1.452 ± 0.279
3.156ValAsn: 3.156 ± 0.55
3.346ValPro: 3.346 ± 0.534
2.083ValGln: 2.083 ± 0.442
4.419ValArg: 4.419 ± 0.484
4.419ValSer: 4.419 ± 0.581
5.113ValThr: 5.113 ± 0.591
5.113ValVal: 5.113 ± 0.466
1.326ValTrp: 1.326 ± 0.27
2.399ValTyr: 2.399 ± 0.442
0.0ValXaa: 0.0 ± 0.0
Trp
1.704TrpAla: 1.704 ± 0.413
0.252TrpCys: 0.252 ± 0.144
1.515TrpAsp: 1.515 ± 0.337
1.452TrpGlu: 1.452 ± 0.294
0.694TrpPhe: 0.694 ± 0.218
1.515TrpGly: 1.515 ± 0.315
0.505TrpHis: 0.505 ± 0.228
1.136TrpIle: 1.136 ± 0.25
0.694TrpLys: 0.694 ± 0.189
1.199TrpLeu: 1.199 ± 0.278
0.442TrpMet: 0.442 ± 0.145
0.568TrpAsn: 0.568 ± 0.202
1.01TrpPro: 1.01 ± 0.331
0.947TrpGln: 0.947 ± 0.229
0.947TrpArg: 0.947 ± 0.217
1.326TrpSer: 1.326 ± 0.287
1.515TrpThr: 1.515 ± 0.315
1.199TrpVal: 1.199 ± 0.279
0.505TrpTrp: 0.505 ± 0.196
0.821TrpTyr: 0.821 ± 0.267
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.651TyrAla: 2.651 ± 0.523
0.126TyrCys: 0.126 ± 0.103
2.146TyrAsp: 2.146 ± 0.325
2.02TyrGlu: 2.02 ± 0.387
0.884TyrPhe: 0.884 ± 0.205
2.714TyrGly: 2.714 ± 0.441
0.316TyrHis: 0.316 ± 0.135
1.389TyrIle: 1.389 ± 0.289
1.262TyrLys: 1.262 ± 0.289
2.841TyrLeu: 2.841 ± 0.388
0.821TyrMet: 0.821 ± 0.226
1.136TyrAsn: 1.136 ± 0.241
1.389TyrPro: 1.389 ± 0.285
1.389TyrGln: 1.389 ± 0.31
2.02TyrArg: 2.02 ± 0.412
1.767TyrSer: 1.767 ± 0.305
1.767TyrThr: 1.767 ± 0.294
2.209TyrVal: 2.209 ± 0.417
0.442TyrTrp: 0.442 ± 0.24
0.947TyrTyr: 0.947 ± 0.255
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 90 proteins (15843 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski