Amino acid dipepetide frequency for Wenling toti-like virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.342AlaAla: 9.342 ± 1.918
1.946AlaCys: 1.946 ± 0.549
5.839AlaAsp: 5.839 ± 1.05
4.282AlaGlu: 4.282 ± 0.73
0.0AlaPhe: 0.0 ± 0.0
7.785AlaGly: 7.785 ± 0.406
3.503AlaHis: 3.503 ± 2.062
5.06AlaIle: 5.06 ± 0.592
2.725AlaLys: 2.725 ± 1.976
8.174AlaLeu: 8.174 ± 1.751
2.336AlaMet: 2.336 ± 0.778
1.946AlaAsn: 1.946 ± 0.048
4.671AlaPro: 4.671 ± 0.363
3.893AlaGln: 3.893 ± 0.692
4.671AlaArg: 4.671 ± 0.959
6.617AlaSer: 6.617 ± 0.315
5.45AlaThr: 5.45 ± 1.417
5.06AlaVal: 5.06 ± 1.188
1.557AlaTrp: 1.557 ± 0.916
2.725AlaTyr: 2.725 ± 1.379
0.0AlaXaa: 0.0 ± 0.0
Cys
0.779CysAla: 0.779 ± 0.458
0.0CysCys: 0.0 ± 0.0
0.389CysAsp: 0.389 ± 0.367
0.389CysGlu: 0.389 ± 0.229
0.0CysPhe: 0.0 ± 0.0
1.557CysGly: 1.557 ± 0.916
0.0CysHis: 0.0 ± 0.0
0.389CysIle: 0.389 ± 0.367
0.389CysLys: 0.389 ± 0.367
1.557CysLeu: 1.557 ± 0.32
0.779CysMet: 0.779 ± 0.138
1.168CysAsn: 1.168 ± 0.506
2.725CysPro: 2.725 ± 0.41
1.557CysGln: 1.557 ± 0.32
1.168CysArg: 1.168 ± 0.687
0.779CysSer: 0.779 ± 0.458
0.0CysThr: 0.0 ± 0.0
1.168CysVal: 1.168 ± 0.091
0.0CysTrp: 0.0 ± 0.0
0.779CysTyr: 0.779 ± 0.138
0.0CysXaa: 0.0 ± 0.0
Asp
6.617AspAla: 6.617 ± 0.912
1.168AspCys: 1.168 ± 0.687
4.671AspAsp: 4.671 ± 0.83
3.893AspGlu: 3.893 ± 0.095
2.725AspPhe: 2.725 ± 0.186
4.282AspGly: 4.282 ± 1.327
1.557AspHis: 1.557 ± 0.873
3.893AspIle: 3.893 ± 0.501
1.557AspLys: 1.557 ± 0.32
4.282AspLeu: 4.282 ± 0.134
0.779AspMet: 0.779 ± 0.138
2.336AspAsn: 2.336 ± 0.778
2.336AspPro: 2.336 ± 0.778
1.946AspGln: 1.946 ± 0.549
2.725AspArg: 2.725 ± 1.007
5.839AspSer: 5.839 ± 0.453
5.06AspThr: 5.06 ± 0.601
5.06AspVal: 5.06 ± 0.601
0.389AspTrp: 0.389 ± 0.229
2.336AspTyr: 2.336 ± 0.181
0.0AspXaa: 0.0 ± 0.0
Glu
3.114GluAla: 3.114 ± 0.043
2.336GluCys: 2.336 ± 0.415
2.336GluAsp: 2.336 ± 1.374
2.336GluGlu: 2.336 ± 1.012
3.114GluPhe: 3.114 ± 0.554
2.725GluGly: 2.725 ± 1.603
1.168GluHis: 1.168 ± 1.102
2.336GluIle: 2.336 ± 1.608
0.779GluLys: 0.779 ± 0.138
5.06GluLeu: 5.06 ± 0.005
0.389GluMet: 0.389 ± 0.367
1.557GluAsn: 1.557 ± 0.916
1.946GluPro: 1.946 ± 0.644
0.389GluGln: 0.389 ± 0.229
1.946GluArg: 1.946 ± 1.241
3.503GluSer: 3.503 ± 0.272
2.336GluThr: 2.336 ± 0.778
0.779GluVal: 0.779 ± 0.138
1.946GluTrp: 1.946 ± 1.241
2.725GluTyr: 2.725 ± 2.572
0.0GluXaa: 0.0 ± 0.0
Phe
2.725PheAla: 2.725 ± 0.41
0.389PheCys: 0.389 ± 0.229
2.336PheAsp: 2.336 ± 1.012
1.168PheGlu: 1.168 ± 1.102
0.779PhePhe: 0.779 ± 0.458
3.893PheGly: 3.893 ± 1.288
1.557PheHis: 1.557 ± 0.277
1.946PheIle: 1.946 ± 1.241
1.946PheLys: 1.946 ± 1.837
3.114PheLeu: 3.114 ± 0.639
0.0PheMet: 0.0 ± 0.0
0.779PheAsn: 0.779 ± 0.458
2.725PhePro: 2.725 ± 0.186
0.0PheGln: 0.0 ± 0.0
1.557PheArg: 1.557 ± 0.277
3.893PheSer: 3.893 ± 1.694
1.557PheThr: 1.557 ± 0.277
2.336PheVal: 2.336 ± 1.012
0.389PheTrp: 0.389 ± 0.367
0.389PheTyr: 0.389 ± 0.229
0.0PheXaa: 0.0 ± 0.0
Gly
2.725GlyAla: 2.725 ± 0.41
0.0GlyCys: 0.0 ± 0.0
3.114GlyAsp: 3.114 ± 0.639
3.893GlyGlu: 3.893 ± 1.288
3.114GlyPhe: 3.114 ± 0.639
4.671GlyGly: 4.671 ± 0.234
1.946GlyHis: 1.946 ± 0.048
5.06GlyIle: 5.06 ± 1.188
4.282GlyLys: 4.282 ± 0.463
6.228GlyLeu: 6.228 ± 0.086
1.168GlyMet: 1.168 ± 0.687
3.114GlyAsn: 3.114 ± 0.639
5.839GlyPro: 5.839 ± 1.646
1.946GlyGln: 1.946 ± 0.048
4.671GlyArg: 4.671 ± 0.83
6.228GlySer: 6.228 ± 1.279
5.45GlyThr: 5.45 ± 0.372
5.45GlyVal: 5.45 ± 0.821
1.168GlyTrp: 1.168 ± 0.506
3.503GlyTyr: 3.503 ± 0.869
0.0GlyXaa: 0.0 ± 0.0
His
2.725HisAla: 2.725 ± 0.41
0.0HisCys: 0.0 ± 0.0
1.557HisAsp: 1.557 ± 0.873
2.336HisGlu: 2.336 ± 0.415
0.0HisPhe: 0.0 ± 0.0
3.114HisGly: 3.114 ± 1.15
0.0HisHis: 0.0 ± 0.0
0.779HisIle: 0.779 ± 0.735
0.0HisLys: 0.0 ± 0.0
2.725HisLeu: 2.725 ± 0.186
0.779HisMet: 0.779 ± 0.285
0.779HisAsn: 0.779 ± 0.138
0.779HisPro: 0.779 ± 0.138
0.779HisGln: 0.779 ± 0.138
2.336HisArg: 2.336 ± 1.012
1.946HisSer: 1.946 ± 0.549
1.168HisThr: 1.168 ± 0.506
1.168HisVal: 1.168 ± 0.687
0.0HisTrp: 0.0 ± 0.0
1.946HisTyr: 1.946 ± 0.048
0.0HisXaa: 0.0 ± 0.0
Ile
5.839IleAla: 5.839 ± 0.453
1.168IleCys: 1.168 ± 0.091
2.336IleAsp: 2.336 ± 0.415
1.946IleGlu: 1.946 ± 0.048
1.946IlePhe: 1.946 ± 0.644
2.725IleGly: 2.725 ± 1.007
1.168IleHis: 1.168 ± 0.506
3.114IleIle: 3.114 ± 0.043
1.168IleLys: 1.168 ± 0.506
3.893IleLeu: 3.893 ± 1.098
0.779IleMet: 0.779 ± 0.138
0.389IleAsn: 0.389 ± 0.367
5.06IlePro: 5.06 ± 0.601
1.557IleGln: 1.557 ± 0.277
4.282IleArg: 4.282 ± 0.463
1.946IleSer: 1.946 ± 0.048
5.06IleThr: 5.06 ± 2.391
0.779IleVal: 0.779 ± 0.138
0.0IleTrp: 0.0 ± 0.0
1.946IleTyr: 1.946 ± 0.644
0.0IleXaa: 0.0 ± 0.0
Lys
2.336LysAla: 2.336 ± 0.181
0.389LysCys: 0.389 ± 0.367
1.168LysAsp: 1.168 ± 1.102
0.779LysGlu: 0.779 ± 0.735
1.168LysPhe: 1.168 ± 1.102
1.557LysGly: 1.557 ± 0.873
0.389LysHis: 0.389 ± 0.367
1.557LysIle: 1.557 ± 1.47
1.557LysLys: 1.557 ± 0.916
5.06LysLeu: 5.06 ± 0.005
0.779LysMet: 0.779 ± 0.458
1.946LysAsn: 1.946 ± 1.241
2.336LysPro: 2.336 ± 0.415
1.168LysGln: 1.168 ± 0.091
3.893LysArg: 3.893 ± 0.095
1.557LysSer: 1.557 ± 0.277
2.336LysThr: 2.336 ± 0.415
1.557LysVal: 1.557 ± 0.873
1.168LysTrp: 1.168 ± 0.506
2.336LysTyr: 2.336 ± 1.012
0.0LysXaa: 0.0 ± 0.0
Leu
11.288LeuAla: 11.288 ± 1.112
1.168LeuCys: 1.168 ± 0.687
7.007LeuAsp: 7.007 ± 0.544
1.557LeuGlu: 1.557 ± 0.32
2.725LeuPhe: 2.725 ± 0.41
5.06LeuGly: 5.06 ± 1.188
0.779LeuHis: 0.779 ± 0.138
3.893LeuIle: 3.893 ± 0.095
4.282LeuLys: 4.282 ± 0.463
10.899LeuLeu: 10.899 ± 1.045
1.946LeuMet: 1.946 ± 0.048
4.282LeuAsn: 4.282 ± 0.134
8.564LeuPro: 8.564 ± 2.057
3.114LeuGln: 3.114 ± 1.236
5.45LeuArg: 5.45 ± 2.758
7.396LeuSer: 7.396 ± 0.177
5.06LeuThr: 5.06 ± 0.601
5.06LeuVal: 5.06 ± 1.188
1.946LeuTrp: 1.946 ± 1.241
3.114LeuTyr: 3.114 ± 1.747
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.779MetGlu: 0.779 ± 0.138
0.779MetPhe: 0.779 ± 0.735
1.557MetGly: 1.557 ± 0.32
1.168MetHis: 1.168 ± 0.687
1.557MetIle: 1.557 ± 0.277
1.557MetLys: 1.557 ± 0.873
0.389MetLeu: 0.389 ± 0.229
0.0MetMet: 0.0 ± 0.0
0.389MetAsn: 0.389 ± 0.229
0.779MetPro: 0.779 ± 0.458
0.779MetGln: 0.779 ± 0.458
0.779MetArg: 0.779 ± 0.458
0.779MetSer: 0.779 ± 0.138
3.503MetThr: 3.503 ± 0.921
0.779MetVal: 0.779 ± 0.138
0.389MetTrp: 0.389 ± 0.367
0.389MetTyr: 0.389 ± 0.229
0.0MetXaa: 0.0 ± 0.0
Asn
3.893AsnAla: 3.893 ± 0.095
0.779AsnCys: 0.779 ± 0.458
3.114AsnAsp: 3.114 ± 1.236
3.114AsnGlu: 3.114 ± 0.554
0.389AsnPhe: 0.389 ± 0.229
1.168AsnGly: 1.168 ± 0.687
0.0AsnHis: 0.0 ± 0.0
0.779AsnIle: 0.779 ± 0.138
0.389AsnLys: 0.389 ± 0.229
3.114AsnLeu: 3.114 ± 1.15
0.389AsnMet: 0.389 ± 0.367
1.168AsnAsn: 1.168 ± 0.687
3.503AsnPro: 3.503 ± 0.272
1.168AsnGln: 1.168 ± 0.687
2.336AsnArg: 2.336 ± 0.181
3.114AsnSer: 3.114 ± 0.639
1.168AsnThr: 1.168 ± 0.091
2.725AsnVal: 2.725 ± 0.41
1.168AsnTrp: 1.168 ± 0.506
0.389AsnTyr: 0.389 ± 0.367
0.0AsnXaa: 0.0 ± 0.0
Pro
6.228ProAla: 6.228 ± 1.279
0.0ProCys: 0.0 ± 0.0
6.228ProAsp: 6.228 ± 1.875
2.725ProGlu: 2.725 ± 1.379
2.725ProPhe: 2.725 ± 1.007
5.839ProGly: 5.839 ± 1.05
1.946ProHis: 1.946 ± 0.644
3.503ProIle: 3.503 ± 0.921
2.336ProLys: 2.336 ± 0.778
5.06ProLeu: 5.06 ± 0.005
1.168ProMet: 1.168 ± 0.091
0.389ProAsn: 0.389 ± 0.367
5.45ProPro: 5.45 ± 0.821
2.336ProGln: 2.336 ± 0.778
3.893ProArg: 3.893 ± 0.095
6.617ProSer: 6.617 ± 0.912
8.564ProThr: 8.564 ± 3.25
4.671ProVal: 4.671 ± 0.363
1.946ProTrp: 1.946 ± 1.837
0.389ProTyr: 0.389 ± 0.229
0.0ProXaa: 0.0 ± 0.0
Gln
2.336GlnAla: 2.336 ± 0.778
1.168GlnCys: 1.168 ± 0.687
1.557GlnAsp: 1.557 ± 0.916
0.779GlnGlu: 0.779 ± 0.458
1.946GlnPhe: 1.946 ± 0.644
3.114GlnGly: 3.114 ± 0.043
1.557GlnHis: 1.557 ± 0.277
1.168GlnIle: 1.168 ± 0.091
0.779GlnLys: 0.779 ± 0.138
3.893GlnLeu: 3.893 ± 1.694
0.389GlnMet: 0.389 ± 0.367
1.557GlnAsn: 1.557 ± 0.916
0.779GlnPro: 0.779 ± 0.458
0.779GlnGln: 0.779 ± 0.458
1.946GlnArg: 1.946 ± 1.145
3.114GlnSer: 3.114 ± 1.236
2.725GlnThr: 2.725 ± 0.783
1.946GlnVal: 1.946 ± 1.241
0.0GlnTrp: 0.0 ± 0.0
0.389GlnTyr: 0.389 ± 0.367
0.0GlnXaa: 0.0 ± 0.0
Arg
5.06ArgAla: 5.06 ± 0.601
0.389ArgCys: 0.389 ± 0.229
3.503ArgAsp: 3.503 ± 0.869
3.503ArgGlu: 3.503 ± 0.325
3.503ArgPhe: 3.503 ± 1.518
5.45ArgGly: 5.45 ± 0.372
1.168ArgHis: 1.168 ± 0.091
1.946ArgIle: 1.946 ± 0.048
2.336ArgLys: 2.336 ± 1.012
5.06ArgLeu: 5.06 ± 0.005
1.557ArgMet: 1.557 ± 0.32
2.336ArgAsn: 2.336 ± 0.415
4.282ArgPro: 4.282 ± 0.134
3.114ArgGln: 3.114 ± 0.554
4.282ArgArg: 4.282 ± 1.059
4.671ArgSer: 4.671 ± 1.556
3.893ArgThr: 3.893 ± 0.095
4.671ArgVal: 4.671 ± 0.234
0.779ArgTrp: 0.779 ± 0.458
1.557ArgTyr: 1.557 ± 0.32
0.0ArgXaa: 0.0 ± 0.0
Ser
7.785SerAla: 7.785 ± 1.002
0.779SerCys: 0.779 ± 0.138
7.785SerAsp: 7.785 ± 2.195
3.114SerGlu: 3.114 ± 0.043
3.114SerPhe: 3.114 ± 0.639
8.564SerGly: 8.564 ± 0.267
1.557SerHis: 1.557 ± 0.277
4.282SerIle: 4.282 ± 0.73
1.946SerLys: 1.946 ± 0.048
5.839SerLeu: 5.839 ± 0.74
1.168SerMet: 1.168 ± 0.506
3.893SerAsn: 3.893 ± 1.098
4.671SerPro: 4.671 ± 0.234
2.336SerGln: 2.336 ± 0.778
2.725SerArg: 2.725 ± 0.186
7.007SerSer: 7.007 ± 0.544
6.228SerThr: 6.228 ± 1.279
5.45SerVal: 5.45 ± 0.224
3.114SerTrp: 3.114 ± 0.043
0.779SerTyr: 0.779 ± 0.458
0.0SerXaa: 0.0 ± 0.0
Thr
6.617ThrAla: 6.617 ± 0.912
0.779ThrCys: 0.779 ± 0.138
4.671ThrAsp: 4.671 ± 0.363
1.946ThrGlu: 1.946 ± 0.048
2.725ThrPhe: 2.725 ± 1.379
3.503ThrGly: 3.503 ± 0.921
2.725ThrHis: 2.725 ± 0.186
3.114ThrIle: 3.114 ± 0.043
2.725ThrLys: 2.725 ± 1.976
8.564ThrLeu: 8.564 ± 0.267
0.779ThrMet: 0.779 ± 0.735
2.336ThrAsn: 2.336 ± 0.181
5.45ThrPro: 5.45 ± 0.821
3.503ThrGln: 3.503 ± 0.272
6.228ThrArg: 6.228 ± 1.279
7.007ThrSer: 7.007 ± 1.842
5.06ThrThr: 5.06 ± 0.592
4.671ThrVal: 4.671 ± 1.556
0.389ThrTrp: 0.389 ± 0.367
2.725ThrTyr: 2.725 ± 0.186
0.0ThrXaa: 0.0 ± 0.0
Val
4.671ValAla: 4.671 ± 0.959
1.557ValCys: 1.557 ± 0.277
2.725ValAsp: 2.725 ± 0.186
1.946ValGlu: 1.946 ± 0.048
1.557ValPhe: 1.557 ± 0.873
4.671ValGly: 4.671 ± 2.152
1.946ValHis: 1.946 ± 1.241
0.779ValIle: 0.779 ± 0.138
2.725ValLys: 2.725 ± 0.783
6.617ValLeu: 6.617 ± 0.282
0.389ValMet: 0.389 ± 0.229
2.336ValAsn: 2.336 ± 0.181
6.617ValPro: 6.617 ± 0.912
0.779ValGln: 0.779 ± 0.458
5.45ValArg: 5.45 ± 0.224
4.282ValSer: 4.282 ± 0.73
7.007ValThr: 7.007 ± 1.246
2.725ValVal: 2.725 ± 1.603
1.168ValTrp: 1.168 ± 0.091
0.389ValTyr: 0.389 ± 0.367
0.0ValXaa: 0.0 ± 0.0
Trp
1.168TrpAla: 1.168 ± 0.091
0.389TrpCys: 0.389 ± 0.367
1.946TrpAsp: 1.946 ± 1.241
0.779TrpGlu: 0.779 ± 0.458
0.0TrpPhe: 0.0 ± 0.0
1.557TrpGly: 1.557 ± 0.277
0.389TrpHis: 0.389 ± 0.367
1.557TrpIle: 1.557 ± 0.277
0.0TrpLys: 0.0 ± 0.0
1.557TrpLeu: 1.557 ± 0.277
0.0TrpMet: 0.0 ± 0.23
0.779TrpAsn: 0.779 ± 0.735
1.946TrpPro: 1.946 ± 0.644
0.0TrpGln: 0.0 ± 0.0
2.336TrpArg: 2.336 ± 0.181
1.168TrpSer: 1.168 ± 1.102
0.389TrpThr: 0.389 ± 0.229
1.557TrpVal: 1.557 ± 0.277
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.336TyrAla: 2.336 ± 1.012
1.168TyrCys: 1.168 ± 0.091
1.168TyrAsp: 1.168 ± 0.506
1.557TyrGlu: 1.557 ± 0.873
1.168TyrPhe: 1.168 ± 0.506
0.779TyrGly: 0.779 ± 0.735
0.389TyrHis: 0.389 ± 0.367
0.389TyrIle: 0.389 ± 0.367
1.557TyrLys: 1.557 ± 0.873
3.503TyrLeu: 3.503 ± 0.325
0.389TyrMet: 0.389 ± 0.229
0.389TyrAsn: 0.389 ± 0.229
1.557TyrPro: 1.557 ± 0.916
0.779TyrGln: 0.779 ± 0.458
0.389TyrArg: 0.389 ± 0.367
4.671TyrSer: 4.671 ± 0.234
3.503TyrThr: 3.503 ± 0.921
2.725TyrVal: 2.725 ± 1.379
0.389TyrTrp: 0.389 ± 0.229
0.389TyrTyr: 0.389 ± 0.367
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2570 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski