Amino acid dipepetide frequency for Macrophomina phaseolina (strain MS6) (Charcoal rot fungus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.085AlaAla: 11.085 ± 0.075	1.201AlaCys: 1.201 ± 0.014	4.767AlaAsp: 4.767 ± 0.031	5.679AlaGlu: 5.679 ± 0.044	3.407AlaPhe: 3.407 ± 0.028	6.478AlaGly: 6.478 ± 0.039	2.05AlaHis: 2.05 ± 0.019	4.139AlaIle: 4.139 ± 0.026	4.164AlaLys: 4.164 ± 0.036	8.434AlaLeu: 8.434 ± 0.047	2.008AlaMet: 2.008 ± 0.018	3.114AlaAsn: 3.114 ± 0.021	5.364AlaPro: 5.364 ± 0.045	3.67AlaGln: 3.67 ± 0.028	5.59AlaArg: 5.59 ± 0.033	7.772AlaSer: 7.772 ± 0.045	5.561AlaThr: 5.561 ± 0.041	5.845AlaVal: 5.845 ± 0.039	1.331AlaTrp: 1.331 ± 0.017	2.372AlaTyr: 2.372 ± 0.02	0.0AlaXaa: 0.0 ± 0.0
Cys	1.058CysAla: 1.058 ± 0.014	0.287CysCys: 0.287 ± 0.008	0.62CysAsp: 0.62 ± 0.01	0.622CysGlu: 0.622 ± 0.012	0.557CysPhe: 0.557 ± 0.011	0.971CysGly: 0.971 ± 0.015	0.325CysHis: 0.325 ± 0.007	0.689CysIle: 0.689 ± 0.011	0.517CysLys: 0.517 ± 0.01	1.236CysLeu: 1.236 ± 0.016	0.29CysMet: 0.29 ± 0.007	0.437CysAsn: 0.437 ± 0.009	0.694CysPro: 0.694 ± 0.014	0.449CysGln: 0.449 ± 0.01	0.833CysArg: 0.833 ± 0.013	0.993CysSer: 0.993 ± 0.014	0.722CysThr: 0.722 ± 0.012	0.821CysVal: 0.821 ± 0.012	0.221CysTrp: 0.221 ± 0.006	0.363CysTyr: 0.363 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	5.247AspAla: 5.247 ± 0.033	0.64AspCys: 0.64 ± 0.011	4.116AspAsp: 4.116 ± 0.038	4.424AspGlu: 4.424 ± 0.04	2.216AspPhe: 2.216 ± 0.021	4.263AspGly: 4.263 ± 0.029	1.163AspHis: 1.163 ± 0.015	2.779AspIle: 2.779 ± 0.026	2.266AspLys: 2.266 ± 0.024	4.82AspLeu: 4.82 ± 0.032	1.171AspMet: 1.171 ± 0.014	1.733AspAsn: 1.733 ± 0.018	3.378AspPro: 3.378 ± 0.024	1.737AspGln: 1.737 ± 0.017	3.0AspArg: 3.0 ± 0.026	3.847AspSer: 3.847 ± 0.028	2.763AspThr: 2.763 ± 0.021	3.733AspVal: 3.733 ± 0.032	0.917AspTrp: 0.917 ± 0.014	1.57AspTyr: 1.57 ± 0.018	0.0AspXaa: 0.0 ± 0.0
Glu	5.734GluAla: 5.734 ± 0.044	0.619GluCys: 0.619 ± 0.011	4.144GluAsp: 4.144 ± 0.038	5.628GluGlu: 5.628 ± 0.059	1.843GluPhe: 1.843 ± 0.019	3.99GluGly: 3.99 ± 0.032	1.461GluHis: 1.461 ± 0.017	2.809GluIle: 2.809 ± 0.024	3.784GluLys: 3.784 ± 0.041	5.221GluLeu: 5.221 ± 0.041	1.446GluMet: 1.446 ± 0.016	2.138GluAsn: 2.138 ± 0.02	2.767GluPro: 2.767 ± 0.032	2.574GluGln: 2.574 ± 0.028	4.339GluArg: 4.339 ± 0.037	3.959GluSer: 3.959 ± 0.032	3.213GluThr: 3.213 ± 0.027	3.581GluVal: 3.581 ± 0.025	0.923GluTrp: 0.923 ± 0.013	1.641GluTyr: 1.641 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	3.299PheAla: 3.299 ± 0.024	0.58PheCys: 0.58 ± 0.01	2.264PheAsp: 2.264 ± 0.019	2.132PheGlu: 2.132 ± 0.017	1.754PhePhe: 1.754 ± 0.021	2.917PheGly: 2.917 ± 0.03	0.889PheHis: 0.889 ± 0.012	1.68PheIle: 1.68 ± 0.018	1.458PheLys: 1.458 ± 0.018	3.426PheLeu: 3.426 ± 0.029	0.759PheMet: 0.759 ± 0.012	1.394PheAsn: 1.394 ± 0.017	2.008PhePro: 2.008 ± 0.021	1.317PheGln: 1.317 ± 0.015	1.998PheArg: 1.998 ± 0.018	3.018PheSer: 3.018 ± 0.027	2.135PheThr: 2.135 ± 0.024	2.479PheVal: 2.479 ± 0.021	0.673PheTrp: 0.673 ± 0.011	1.087PheTyr: 1.087 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	6.063GlyAla: 6.063 ± 0.043	0.928GlyCys: 0.928 ± 0.015	3.679GlyAsp: 3.679 ± 0.027	3.891GlyGlu: 3.891 ± 0.026	2.806GlyPhe: 2.806 ± 0.024	6.148GlyGly: 6.148 ± 0.056	1.684GlyHis: 1.684 ± 0.018	3.382GlyIle: 3.382 ± 0.024	3.479GlyLys: 3.479 ± 0.03	6.012GlyLeu: 6.012 ± 0.039	1.63GlyMet: 1.63 ± 0.022	2.495GlyAsn: 2.495 ± 0.025	3.473GlyPro: 3.473 ± 0.028	2.52GlyGln: 2.52 ± 0.024	4.325GlyArg: 4.325 ± 0.033	5.76GlySer: 5.76 ± 0.041	4.025GlyThr: 4.025 ± 0.036	4.52GlyVal: 4.52 ± 0.031	1.218GlyTrp: 1.218 ± 0.014	2.118GlyTyr: 2.118 ± 0.023	0.0GlyXaa: 0.0 ± 0.0
His	2.125HisAla: 2.125 ± 0.02	0.363HisCys: 0.363 ± 0.009	1.265HisAsp: 1.265 ± 0.015	1.331HisGlu: 1.331 ± 0.017	0.955HisPhe: 0.955 ± 0.014	1.747HisGly: 1.747 ± 0.017	0.886HisHis: 0.886 ± 0.016	1.133HisIle: 1.133 ± 0.015	0.892HisLys: 0.892 ± 0.012	2.249HisLeu: 2.249 ± 0.021	0.466HisMet: 0.466 ± 0.008	0.805HisAsn: 0.805 ± 0.012	1.683HisPro: 1.683 ± 0.02	1.002HisGln: 1.002 ± 0.013	1.612HisArg: 1.612 ± 0.019	1.823HisSer: 1.823 ± 0.02	1.265HisThr: 1.265 ± 0.015	1.492HisVal: 1.492 ± 0.018	0.365HisTrp: 0.365 ± 0.008	0.685HisTyr: 0.685 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	4.102IleAla: 4.102 ± 0.027	0.704IleCys: 0.704 ± 0.01	2.666IleAsp: 2.666 ± 0.021	2.677IleGlu: 2.677 ± 0.025	1.876IlePhe: 1.876 ± 0.019	3.015IleGly: 3.015 ± 0.023	1.104IleHis: 1.104 ± 0.014	2.236IleIle: 2.236 ± 0.024	2.015IleLys: 2.015 ± 0.022	4.128IleLeu: 4.128 ± 0.031	0.954IleMet: 0.954 ± 0.014	1.685IleAsn: 1.685 ± 0.019	2.861IlePro: 2.861 ± 0.021	1.706IleGln: 1.706 ± 0.017	2.689IleArg: 2.689 ± 0.021	3.564IleSer: 3.564 ± 0.024	2.738IleThr: 2.738 ± 0.031	2.977IleVal: 2.977 ± 0.022	0.697IleTrp: 0.697 ± 0.011	1.307IleTyr: 1.307 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	4.357LysAla: 4.357 ± 0.035	0.474LysCys: 0.474 ± 0.009	2.661LysAsp: 2.661 ± 0.026	3.397LysGlu: 3.397 ± 0.035	1.382LysPhe: 1.382 ± 0.018	2.954LysGly: 2.954 ± 0.028	1.132LysHis: 1.132 ± 0.015	2.051LysIle: 2.051 ± 0.021	3.349LysLys: 3.349 ± 0.044	3.923LysLeu: 3.923 ± 0.034	0.986LysMet: 0.986 ± 0.013	1.675LysAsn: 1.675 ± 0.019	2.676LysPro: 2.676 ± 0.026	1.864LysGln: 1.864 ± 0.022	3.487LysArg: 3.487 ± 0.031	3.182LysSer: 3.182 ± 0.027	2.637LysThr: 2.637 ± 0.021	2.667LysVal: 2.667 ± 0.023	0.648LysTrp: 0.648 ± 0.012	1.297LysTyr: 1.297 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	8.257LeuAla: 8.257 ± 0.043	1.242LeuCys: 1.242 ± 0.015	4.975LeuAsp: 4.975 ± 0.035	5.358LeuGlu: 5.358 ± 0.042	3.348LeuPhe: 3.348 ± 0.028	5.787LeuGly: 5.787 ± 0.036	2.292LeuHis: 2.292 ± 0.02	3.661LeuIle: 3.661 ± 0.026	3.976LeuLys: 3.976 ± 0.033	8.338LeuLeu: 8.338 ± 0.057	1.722LeuMet: 1.722 ± 0.016	3.035LeuAsn: 3.035 ± 0.028	5.636LeuPro: 5.636 ± 0.042	3.699LeuGln: 3.699 ± 0.027	6.088LeuArg: 6.088 ± 0.037	7.085LeuSer: 7.085 ± 0.045	4.671LeuThr: 4.671 ± 0.033	5.363LeuVal: 5.363 ± 0.029	1.223LeuTrp: 1.223 ± 0.016	2.314LeuTyr: 2.314 ± 0.021	0.0LeuXaa: 0.0 ± 0.0
Met	2.205MetAla: 2.205 ± 0.021	0.248MetCys: 0.248 ± 0.006	1.204MetAsp: 1.204 ± 0.014	1.233MetGlu: 1.233 ± 0.014	0.697MetPhe: 0.697 ± 0.011	1.421MetGly: 1.421 ± 0.021	0.496MetHis: 0.496 ± 0.01	0.898MetIle: 0.898 ± 0.012	0.971MetLys: 0.971 ± 0.014	1.87MetLeu: 1.87 ± 0.019	0.553MetMet: 0.553 ± 0.01	0.747MetAsn: 0.747 ± 0.012	1.284MetPro: 1.284 ± 0.017	0.872MetGln: 0.872 ± 0.014	1.341MetArg: 1.341 ± 0.014	1.709MetSer: 1.709 ± 0.018	1.186MetThr: 1.186 ± 0.017	1.253MetVal: 1.253 ± 0.016	0.292MetTrp: 0.292 ± 0.007	0.511MetTyr: 0.511 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	3.293AsnAla: 3.293 ± 0.026	0.446AsnCys: 0.446 ± 0.008	1.842AsnAsp: 1.842 ± 0.021	1.926AsnGlu: 1.926 ± 0.021	1.361AsnPhe: 1.361 ± 0.012	2.995AsnGly: 2.995 ± 0.031	0.815AsnHis: 0.815 ± 0.012	1.878AsnIle: 1.878 ± 0.017	1.505AsnLys: 1.505 ± 0.019	3.032AsnLeu: 3.032 ± 0.022	0.765AsnMet: 0.765 ± 0.012	1.429AsnAsn: 1.429 ± 0.02	2.312AsnPro: 2.312 ± 0.021	1.238AsnGln: 1.238 ± 0.014	1.859AsnArg: 1.859 ± 0.018	2.613AsnSer: 2.613 ± 0.024	2.1AsnThr: 2.1 ± 0.017	2.239AsnVal: 2.239 ± 0.018	0.554AsnTrp: 0.554 ± 0.01	1.032AsnTyr: 1.032 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	5.978ProAla: 5.978 ± 0.046	0.547ProCys: 0.547 ± 0.011	3.274ProAsp: 3.274 ± 0.025	3.817ProGlu: 3.817 ± 0.031	2.131ProPhe: 2.131 ± 0.018	4.115ProGly: 4.115 ± 0.037	1.436ProHis: 1.436 ± 0.017	2.351ProIle: 2.351 ± 0.021	2.556ProLys: 2.556 ± 0.022	4.812ProLeu: 4.812 ± 0.028	1.032ProMet: 1.032 ± 0.015	2.111ProAsn: 2.111 ± 0.021	5.346ProPro: 5.346 ± 0.062	2.497ProGln: 2.497 ± 0.028	3.58ProArg: 3.58 ± 0.032	5.911ProSer: 5.911 ± 0.055	4.016ProThr: 4.016 ± 0.04	3.594ProVal: 3.594 ± 0.034	0.762ProTrp: 0.762 ± 0.011	1.54ProTyr: 1.54 ± 0.022	0.0ProXaa: 0.0 ± 0.0
Gln	3.588GlnAla: 3.588 ± 0.029	0.447GlnCys: 0.447 ± 0.008	2.02GlnAsp: 2.02 ± 0.018	2.388GlnGlu: 2.388 ± 0.025	1.235GlnPhe: 1.235 ± 0.015	2.33GlnGly: 2.33 ± 0.023	1.135GlnHis: 1.135 ± 0.016	1.698GlnIle: 1.698 ± 0.018	1.898GlnLys: 1.898 ± 0.018	3.413GlnLeu: 3.413 ± 0.031	0.871GlnMet: 0.871 ± 0.014	1.466GlnAsn: 1.466 ± 0.016	2.606GlnPro: 2.606 ± 0.027	2.58GlnGln: 2.58 ± 0.043	2.8GlnArg: 2.8 ± 0.023	2.946GlnSer: 2.946 ± 0.024	2.185GlnThr: 2.185 ± 0.019	2.052GlnVal: 2.052 ± 0.02	0.584GlnTrp: 0.584 ± 0.01	1.122GlnTyr: 1.122 ± 0.014	0.0GlnXaa: 0.0 ± 0.0
Arg	5.382ArgAla: 5.382 ± 0.037	0.815ArgCys: 0.815 ± 0.015	3.353ArgAsp: 3.353 ± 0.029	3.99ArgGlu: 3.99 ± 0.036	2.19ArgPhe: 2.19 ± 0.018	3.889ArgGly: 3.889 ± 0.032	1.633ArgHis: 1.633 ± 0.019	2.915ArgIle: 2.915 ± 0.024	3.545ArgLys: 3.545 ± 0.033	5.705ArgLeu: 5.705 ± 0.039	1.379ArgMet: 1.379 ± 0.016	2.286ArgAsn: 2.286 ± 0.022	3.694ArgPro: 3.694 ± 0.033	2.656ArgGln: 2.656 ± 0.024	5.518ArgArg: 5.518 ± 0.05	4.897ArgSer: 4.897 ± 0.041	3.497ArgThr: 3.497 ± 0.028	3.508ArgVal: 3.508 ± 0.026	1.039ArgTrp: 1.039 ± 0.016	1.678ArgTyr: 1.678 ± 0.018	0.0ArgXaa: 0.0 ± 0.0
Ser	7.452SerAla: 7.452 ± 0.047	0.907SerCys: 0.907 ± 0.013	4.041SerAsp: 4.041 ± 0.028	3.967SerGlu: 3.967 ± 0.032	3.032SerPhe: 3.032 ± 0.026	5.675SerGly: 5.675 ± 0.052	1.844SerHis: 1.844 ± 0.02	3.666SerIle: 3.666 ± 0.025	3.405SerLys: 3.405 ± 0.029	6.809SerLeu: 6.809 ± 0.041	1.609SerMet: 1.609 ± 0.017	2.85SerAsn: 2.85 ± 0.025	5.481SerPro: 5.481 ± 0.045	3.002SerGln: 3.002 ± 0.028	4.878SerArg: 4.878 ± 0.043	8.707SerSer: 8.707 ± 0.086	5.459SerThr: 5.459 ± 0.053	4.567SerVal: 4.567 ± 0.032	1.136SerTrp: 1.136 ± 0.013	2.025SerTyr: 2.025 ± 0.023	0.0SerXaa: 0.0 ± 0.0
Thr	5.662ThrAla: 5.662 ± 0.04	0.735ThrCys: 0.735 ± 0.011	2.724ThrAsp: 2.724 ± 0.021	2.92ThrGlu: 2.92 ± 0.025	2.257ThrPhe: 2.257 ± 0.021	4.184ThrGly: 4.184 ± 0.04	1.267ThrHis: 1.267 ± 0.016	2.868ThrIle: 2.868 ± 0.032	2.396ThrLys: 2.396 ± 0.021	5.101ThrLeu: 5.101 ± 0.037	1.101ThrMet: 1.101 ± 0.014	2.034ThrAsn: 2.034 ± 0.021	4.333ThrPro: 4.333 ± 0.043	2.008ThrGln: 2.008 ± 0.022	3.161ThrArg: 3.161 ± 0.022	5.136ThrSer: 5.136 ± 0.046	4.291ThrThr: 4.291 ± 0.064	3.76ThrVal: 3.76 ± 0.035	0.861ThrTrp: 0.861 ± 0.011	1.624ThrTyr: 1.624 ± 0.02	0.0ThrXaa: 0.0 ± 0.0
Val	5.569ValAla: 5.569 ± 0.038	0.884ValCys: 0.884 ± 0.013	3.654ValAsp: 3.654 ± 0.027	4.036ValGlu: 4.036 ± 0.032	2.457ValPhe: 2.457 ± 0.024	4.183ValGly: 4.183 ± 0.034	1.415ValHis: 1.415 ± 0.017	2.778ValIle: 2.778 ± 0.027	2.754ValLys: 2.754 ± 0.023	5.572ValLeu: 5.572 ± 0.035	1.283ValMet: 1.283 ± 0.017	2.122ValAsn: 2.122 ± 0.022	3.661ValPro: 3.661 ± 0.029	2.359ValGln: 2.359 ± 0.023	3.751ValArg: 3.751 ± 0.027	4.531ValSer: 4.531 ± 0.031	3.377ValThr: 3.377 ± 0.034	4.447ValVal: 4.447 ± 0.04	0.927ValTrp: 0.927 ± 0.015	1.727ValTyr: 1.727 ± 0.019	0.0ValXaa: 0.0 ± 0.0
Trp	1.263TrpAla: 1.263 ± 0.017	0.215TrpCys: 0.215 ± 0.006	0.891TrpAsp: 0.891 ± 0.013	0.881TrpGlu: 0.881 ± 0.012	0.571TrpPhe: 0.571 ± 0.01	0.929TrpGly: 0.929 ± 0.017	0.384TrpHis: 0.384 ± 0.009	0.759TrpIle: 0.759 ± 0.012	0.816TrpLys: 0.816 ± 0.011	1.41TrpLeu: 1.41 ± 0.016	0.37TrpMet: 0.37 ± 0.009	0.614TrpAsn: 0.614 ± 0.01	0.655TrpPro: 0.655 ± 0.012	0.581TrpGln: 0.581 ± 0.01	1.098TrpArg: 1.098 ± 0.012	1.085TrpSer: 1.085 ± 0.015	0.943TrpThr: 0.943 ± 0.014	0.917TrpVal: 0.917 ± 0.014	0.301TrpTrp: 0.301 ± 0.007	0.45TrpTyr: 0.45 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.313TyrAla: 2.313 ± 0.021	0.423TyrCys: 0.423 ± 0.008	1.62TyrAsp: 1.62 ± 0.019	1.517TyrGlu: 1.517 ± 0.018	1.192TyrPhe: 1.192 ± 0.016	2.163TyrGly: 2.163 ± 0.022	0.73TyrHis: 0.73 ± 0.01	1.331TyrIle: 1.331 ± 0.017	1.053TyrLys: 1.053 ± 0.014	2.559TyrLeu: 2.559 ± 0.026	0.596TyrMet: 0.596 ± 0.009	1.065TyrAsn: 1.065 ± 0.014	1.497TyrPro: 1.497 ± 0.02	1.034TyrGln: 1.034 ± 0.013	1.623TyrArg: 1.623 ± 0.016	1.979TyrSer: 1.979 ± 0.021	1.638TyrThr: 1.638 ± 0.022	1.669TyrVal: 1.669 ± 0.017	0.459TyrTrp: 0.459 ± 0.01	0.951TyrTyr: 0.951 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 13803 proteins (5914650 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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