Amino acid dipepetide frequency for Bole Tick Virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.07AlaAla: 10.07 ± 6.497
2.441AlaCys: 2.441 ± 0.874
3.052AlaAsp: 3.052 ± 1.122
4.883AlaGlu: 4.883 ± 1.922
3.357AlaPhe: 3.357 ± 0.584
5.188AlaGly: 5.188 ± 1.142
1.831AlaHis: 1.831 ± 0.132
3.357AlaIle: 3.357 ± 1.725
3.052AlaLys: 3.052 ± 0.966
7.934AlaLeu: 7.934 ± 2.268
2.441AlaMet: 2.441 ± 0.373
3.052AlaAsn: 3.052 ± 0.611
6.408AlaPro: 6.408 ± 4.416
3.967AlaGln: 3.967 ± 1.691
3.967AlaArg: 3.967 ± 1.2
4.577AlaSer: 4.577 ± 1.598
3.052AlaThr: 3.052 ± 1.016
5.798AlaVal: 5.798 ± 0.747
0.61AlaTrp: 0.61 ± 0.631
5.188AlaTyr: 5.188 ± 0.988
0.0AlaXaa: 0.0 ± 0.0
Cys
0.915CysAla: 0.915 ± 0.484
0.0CysCys: 0.0 ± 0.0
1.221CysAsp: 1.221 ± 0.645
0.305CysGlu: 0.305 ± 0.539
0.305CysPhe: 0.305 ± 0.161
0.915CysGly: 0.915 ± 0.785
0.61CysHis: 0.61 ± 0.351
0.305CysIle: 0.305 ± 0.161
1.526CysLys: 1.526 ± 0.806
2.136CysLeu: 2.136 ± 0.341
1.221CysMet: 1.221 ± 0.645
0.61CysAsn: 0.61 ± 0.322
1.221CysPro: 1.221 ± 0.645
0.915CysGln: 0.915 ± 0.474
0.61CysArg: 0.61 ± 0.322
1.831CysSer: 1.831 ± 1.619
1.526CysThr: 1.526 ± 0.636
1.526CysVal: 1.526 ± 0.457
0.305CysTrp: 0.305 ± 0.161
1.526CysTyr: 1.526 ± 0.457
0.0CysXaa: 0.0 ± 0.0
Asp
4.883AspAla: 4.883 ± 0.456
0.915AspCys: 0.915 ± 0.785
3.357AspAsp: 3.357 ± 1.227
2.441AspGlu: 2.441 ± 0.874
1.526AspPhe: 1.526 ± 0.561
3.052AspGly: 3.052 ± 0.611
1.526AspHis: 1.526 ± 0.186
3.052AspIle: 3.052 ± 1.18
2.746AspLys: 2.746 ± 0.19
6.408AspLeu: 6.408 ± 1.528
1.831AspMet: 1.831 ± 0.132
0.61AspAsn: 0.61 ± 0.322
2.136AspPro: 2.136 ± 0.993
1.831AspGln: 1.831 ± 0.722
3.967AspArg: 3.967 ± 2.238
2.441AspSer: 2.441 ± 0.373
1.526AspThr: 1.526 ± 0.806
3.967AspVal: 3.967 ± 0.706
1.526AspTrp: 1.526 ± 0.186
1.221AspTyr: 1.221 ± 0.322
0.0AspXaa: 0.0 ± 0.0
Glu
5.188GluAla: 5.188 ± 2.267
1.526GluCys: 1.526 ± 0.648
2.746GluAsp: 2.746 ± 1.032
2.441GluGlu: 2.441 ± 0.373
2.441GluPhe: 2.441 ± 0.373
3.357GluGly: 3.357 ± 1.038
1.221GluHis: 1.221 ± 0.645
3.967GluIle: 3.967 ± 0.861
1.831GluLys: 1.831 ± 0.967
5.798GluLeu: 5.798 ± 1.178
1.831GluMet: 1.831 ± 0.394
1.221GluAsn: 1.221 ± 0.48
2.441GluPro: 2.441 ± 0.717
1.831GluGln: 1.831 ± 1.402
4.272GluArg: 4.272 ± 1.588
3.662GluSer: 3.662 ± 0.782
3.662GluThr: 3.662 ± 0.504
3.357GluVal: 3.357 ± 1.025
0.61GluTrp: 0.61 ± 0.322
1.526GluTyr: 1.526 ± 0.561
0.0GluXaa: 0.0 ± 0.0
Phe
1.221PheAla: 1.221 ± 0.359
1.221PheCys: 1.221 ± 0.645
2.746PheAsp: 2.746 ± 0.19
3.357PheGlu: 3.357 ± 0.844
1.526PhePhe: 1.526 ± 0.806
2.441PheGly: 2.441 ± 0.957
1.221PheHis: 1.221 ± 0.359
1.831PheIle: 1.831 ± 0.967
1.831PheLys: 1.831 ± 0.132
4.577PheLeu: 4.577 ± 1.365
0.915PheMet: 0.915 ± 0.474
1.221PheAsn: 1.221 ± 0.322
1.831PhePro: 1.831 ± 0.485
1.221PheGln: 1.221 ± 0.322
3.662PheArg: 3.662 ± 0.815
2.441PheSer: 2.441 ± 0.224
1.831PheThr: 1.831 ± 0.722
2.441PheVal: 2.441 ± 0.586
0.305PheTrp: 0.305 ± 0.161
0.61PheTyr: 0.61 ± 0.322
0.0PheXaa: 0.0 ± 0.0
Gly
5.493GlyAla: 5.493 ± 0.899
0.915GlyCys: 0.915 ± 0.316
2.136GlyAsp: 2.136 ± 0.229
4.577GlyGlu: 4.577 ± 0.085
3.357GlyPhe: 3.357 ± 0.515
4.272GlyGly: 4.272 ± 1.323
2.136GlyHis: 2.136 ± 0.912
3.357GlyIle: 3.357 ± 1.025
1.831GlyLys: 1.831 ± 0.632
7.019GlyLeu: 7.019 ± 2.041
3.052GlyMet: 3.052 ± 1.268
0.915GlyAsn: 0.915 ± 0.484
1.831GlyPro: 1.831 ± 0.722
1.831GlyGln: 1.831 ± 0.892
1.526GlyArg: 1.526 ± 0.457
2.746GlySer: 2.746 ± 0.527
2.746GlyThr: 2.746 ± 0.948
5.188GlyVal: 5.188 ± 2.009
1.526GlyTrp: 1.526 ± 0.186
3.357GlyTyr: 3.357 ± 0.404
0.0GlyXaa: 0.0 ± 0.0
His
0.915HisAla: 0.915 ± 1.336
0.61HisCys: 0.61 ± 0.351
1.221HisAsp: 1.221 ± 0.48
1.831HisGlu: 1.831 ± 0.722
0.61HisPhe: 0.61 ± 0.322
0.915HisGly: 0.915 ± 0.316
1.221HisHis: 1.221 ± 0.359
1.526HisIle: 1.526 ± 0.457
1.831HisLys: 1.831 ± 0.585
3.357HisLeu: 3.357 ± 0.515
0.915HisMet: 0.915 ± 0.474
1.526HisAsn: 1.526 ± 0.806
1.831HisPro: 1.831 ± 0.132
1.831HisGln: 1.831 ± 0.632
1.221HisArg: 1.221 ± 0.645
1.831HisSer: 1.831 ± 1.57
1.831HisThr: 1.831 ± 0.485
3.967HisVal: 3.967 ± 1.691
0.61HisTrp: 0.61 ± 0.322
0.915HisTyr: 0.915 ± 0.316
0.0HisXaa: 0.0 ± 0.0
Ile
5.188IleAla: 5.188 ± 1.152
0.61IleCys: 0.61 ± 0.467
1.831IleAsp: 1.831 ± 0.948
3.357IleGlu: 3.357 ± 0.404
0.915IlePhe: 0.915 ± 0.484
2.441IleGly: 2.441 ± 0.961
1.831IleHis: 1.831 ± 0.967
1.526IleIle: 1.526 ± 1.671
1.526IleLys: 1.526 ± 0.806
3.967IleLeu: 3.967 ± 0.706
1.221IleMet: 1.221 ± 0.702
2.441IleAsn: 2.441 ± 0.874
3.052IlePro: 3.052 ± 0.271
2.441IleGln: 2.441 ± 1.29
4.577IleArg: 4.577 ± 0.555
4.272IleSer: 4.272 ± 1.451
3.357IleThr: 3.357 ± 0.515
4.272IleVal: 4.272 ± 0.683
1.526IleTrp: 1.526 ± 0.899
1.831IleTyr: 1.831 ± 0.632
0.0IleXaa: 0.0 ± 0.0
Lys
2.136LysAla: 2.136 ± 0.638
0.915LysCys: 0.915 ± 0.785
2.136LysAsp: 2.136 ± 0.638
1.831LysGlu: 1.831 ± 0.585
3.357LysPhe: 3.357 ± 0.844
2.746LysGly: 2.746 ± 1.032
1.526LysHis: 1.526 ± 0.806
1.221LysIle: 1.221 ± 0.359
1.831LysLys: 1.831 ± 0.722
4.577LysLeu: 4.577 ± 0.085
0.915LysMet: 0.915 ± 0.446
0.0LysAsn: 0.0 ± 0.0
1.831LysPro: 1.831 ± 0.632
1.221LysGln: 1.221 ± 0.359
1.526LysArg: 1.526 ± 0.561
1.831LysSer: 1.831 ± 0.585
3.052LysThr: 3.052 ± 0.915
4.577LysVal: 4.577 ± 1.598
0.305LysTrp: 0.305 ± 0.161
1.526LysTyr: 1.526 ± 0.648
0.0LysXaa: 0.0 ± 0.0
Leu
8.239LeuAla: 8.239 ± 2.715
1.526LeuCys: 1.526 ± 0.806
8.239LeuAsp: 8.239 ± 2.418
4.577LeuGlu: 4.577 ± 1.948
4.883LeuPhe: 4.883 ± 0.232
4.577LeuGly: 4.577 ± 0.598
3.357LeuHis: 3.357 ± 0.404
5.188LeuIle: 5.188 ± 1.521
3.052LeuLys: 3.052 ± 0.574
11.596LeuLeu: 11.596 ± 1.459
2.441LeuMet: 2.441 ± 0.288
3.052LeuAsn: 3.052 ± 0.574
7.019LeuPro: 7.019 ± 1.653
5.798LeuGln: 5.798 ± 0.747
5.188LeuArg: 5.188 ± 2.019
5.493LeuSer: 5.493 ± 0.397
4.272LeuThr: 4.272 ± 0.825
8.239LeuVal: 8.239 ± 1.679
0.915LeuTrp: 0.915 ± 0.484
4.272LeuTyr: 4.272 ± 0.825
0.0LeuXaa: 0.0 ± 0.0
Met
2.441MetAla: 2.441 ± 0.961
0.61MetCys: 0.61 ± 0.351
1.221MetAsp: 1.221 ± 0.645
1.526MetGlu: 1.526 ± 0.186
1.221MetPhe: 1.221 ± 0.792
1.831MetGly: 1.831 ± 1.052
0.915MetHis: 0.915 ± 0.316
2.441MetIle: 2.441 ± 0.957
1.221MetLys: 1.221 ± 0.935
2.136MetLeu: 2.136 ± 0.638
1.831MetMet: 1.831 ± 0.967
0.305MetAsn: 0.305 ± 0.445
1.221MetPro: 1.221 ± 0.48
0.915MetGln: 0.915 ± 0.316
2.136MetArg: 2.136 ± 1.362
2.441MetSer: 2.441 ± 0.957
2.136MetThr: 2.136 ± 0.799
2.136MetVal: 2.136 ± 0.229
0.305MetTrp: 0.305 ± 0.161
1.526MetTyr: 1.526 ± 1.671
0.0MetXaa: 0.0 ± 0.0
Asn
3.052AsnAla: 3.052 ± 1.122
0.61AsnCys: 0.61 ± 0.322
1.221AsnAsp: 1.221 ± 0.935
1.221AsnGlu: 1.221 ± 0.702
2.136AsnPhe: 2.136 ± 0.913
1.221AsnGly: 1.221 ± 0.322
0.915AsnHis: 0.915 ± 0.484
1.831AsnIle: 1.831 ± 0.585
1.221AsnLys: 1.221 ± 0.702
2.136AsnLeu: 2.136 ± 0.726
2.136AsnMet: 2.136 ± 0.799
0.915AsnAsn: 0.915 ± 0.484
1.526AsnPro: 1.526 ± 0.186
0.915AsnGln: 0.915 ± 0.484
1.221AsnArg: 1.221 ± 0.48
0.915AsnSer: 0.915 ± 0.446
1.831AsnThr: 1.831 ± 0.485
2.441AsnVal: 2.441 ± 0.782
0.0AsnTrp: 0.0 ± 0.0
0.915AsnTyr: 0.915 ± 0.484
0.0AsnXaa: 0.0 ± 0.0
Pro
3.662ProAla: 3.662 ± 2.857
0.915ProCys: 0.915 ± 0.484
4.272ProAsp: 4.272 ± 0.458
4.883ProGlu: 4.883 ± 0.718
2.136ProPhe: 2.136 ± 1.128
3.967ProGly: 3.967 ± 1.982
0.61ProHis: 0.61 ± 0.467
2.746ProIle: 2.746 ± 0.527
0.61ProLys: 0.61 ± 0.322
4.272ProLeu: 4.272 ± 0.825
1.831ProMet: 1.831 ± 0.546
2.136ProAsn: 2.136 ± 0.229
3.662ProPro: 3.662 ± 1.022
1.526ProGln: 1.526 ± 0.83
5.188ProArg: 5.188 ± 0.809
3.052ProSer: 3.052 ± 0.372
3.662ProThr: 3.662 ± 1.264
3.357ProVal: 3.357 ± 1.679
0.305ProTrp: 0.305 ± 0.161
2.136ProTyr: 2.136 ± 0.726
0.0ProXaa: 0.0 ± 0.0
Gln
2.441GlnAla: 2.441 ± 1.87
1.221GlnCys: 1.221 ± 0.48
1.221GlnAsp: 1.221 ± 0.48
2.746GlnGlu: 2.746 ± 0.501
1.831GlnPhe: 1.831 ± 0.722
1.831GlnGly: 1.831 ± 0.132
2.441GlnHis: 2.441 ± 1.403
1.526GlnIle: 1.526 ± 0.561
1.526GlnLys: 1.526 ± 0.457
3.052GlnLeu: 3.052 ± 0.574
0.305GlnMet: 0.305 ± 0.161
1.221GlnAsn: 1.221 ± 0.48
3.052GlnPro: 3.052 ± 1.112
3.052GlnGln: 3.052 ± 2.49
2.441GlnArg: 2.441 ± 0.586
3.662GlnSer: 3.662 ± 1.361
3.052GlnThr: 3.052 ± 2.264
3.052GlnVal: 3.052 ± 0.372
0.61GlnTrp: 0.61 ± 0.322
2.136GlnTyr: 2.136 ± 1.362
0.0GlnXaa: 0.0 ± 0.0
Arg
4.272ArgAla: 4.272 ± 0.863
0.915ArgCys: 0.915 ± 0.446
2.136ArgAsp: 2.136 ± 0.638
2.136ArgGlu: 2.136 ± 0.794
0.915ArgPhe: 0.915 ± 0.484
4.883ArgGly: 4.883 ± 2.346
1.526ArgHis: 1.526 ± 0.636
3.357ArgIle: 3.357 ± 1.336
4.577ArgLys: 4.577 ± 1.684
6.408ArgLeu: 6.408 ± 0.84
1.526ArgMet: 1.526 ± 1.194
2.441ArgAsn: 2.441 ± 0.961
2.441ArgPro: 2.441 ± 0.586
2.746ArgGln: 2.746 ± 0.19
3.662ArgArg: 3.662 ± 1.519
3.662ArgSer: 3.662 ± 1.264
2.746ArgThr: 2.746 ± 0.19
6.103ArgVal: 6.103 ± 1.715
1.221ArgTrp: 1.221 ± 0.645
3.662ArgTyr: 3.662 ± 1.343
0.0ArgXaa: 0.0 ± 0.0
Ser
5.798SerAla: 5.798 ± 1.471
1.221SerCys: 1.221 ± 0.792
3.662SerAsp: 3.662 ± 0.504
3.052SerGlu: 3.052 ± 0.611
2.441SerPhe: 2.441 ± 0.782
4.577SerGly: 4.577 ± 0.82
2.441SerHis: 2.441 ± 0.957
3.357SerIle: 3.357 ± 0.844
3.357SerLys: 3.357 ± 1.382
6.408SerLeu: 6.408 ± 1.079
1.831SerMet: 1.831 ± 0.132
0.61SerAsn: 0.61 ± 0.322
5.188SerPro: 5.188 ± 1.559
3.967SerGln: 3.967 ± 1.356
3.052SerArg: 3.052 ± 0.271
2.136SerSer: 2.136 ± 2.56
3.662SerThr: 3.662 ± 1.451
3.357SerVal: 3.357 ± 1.27
0.915SerTrp: 0.915 ± 0.316
2.136SerTyr: 2.136 ± 0.993
0.0SerXaa: 0.0 ± 0.0
Thr
3.357ThrAla: 3.357 ± 1.557
0.915ThrCys: 0.915 ± 0.316
2.441ThrAsp: 2.441 ± 0.717
3.662ThrGlu: 3.662 ± 1.076
0.915ThrPhe: 0.915 ± 0.785
2.746ThrGly: 2.746 ± 0.948
2.136ThrHis: 2.136 ± 0.726
5.493ThrIle: 5.493 ± 0.55
2.746ThrLys: 2.746 ± 0.19
6.408ThrLeu: 6.408 ± 1.58
0.915ThrMet: 0.915 ± 0.484
1.221ThrAsn: 1.221 ± 1.593
3.052ThrPro: 3.052 ± 0.574
1.831ThrGln: 1.831 ± 0.722
3.662ThrArg: 3.662 ± 0.424
3.662ThrSer: 3.662 ± 2.105
3.967ThrThr: 3.967 ± 0.543
3.662ThrVal: 3.662 ± 0.265
1.526ThrTrp: 1.526 ± 0.561
2.136ThrTyr: 2.136 ± 0.726
0.0ThrXaa: 0.0 ± 0.0
Val
9.155ValAla: 9.155 ± 1.76
2.441ValCys: 2.441 ± 0.373
4.272ValAsp: 4.272 ± 0.113
4.577ValGlu: 4.577 ± 1.214
2.746ValPhe: 2.746 ± 0.948
4.577ValGly: 4.577 ± 1.122
1.221ValHis: 1.221 ± 0.322
2.746ValIle: 2.746 ± 0.948
1.526ValLys: 1.526 ± 0.636
7.934ValLeu: 7.934 ± 1.412
1.831ValMet: 1.831 ± 0.485
2.441ValAsn: 2.441 ± 0.224
3.662ValPro: 3.662 ± 1.343
2.441ValGln: 2.441 ± 0.586
5.798ValArg: 5.798 ± 1.659
6.103ValSer: 6.103 ± 3.365
4.272ValThr: 4.272 ± 0.622
2.136ValVal: 2.136 ± 0.726
0.61ValTrp: 0.61 ± 0.351
3.357ValTyr: 3.357 ± 0.515
0.0ValXaa: 0.0 ± 0.0
Trp
2.746TrpAla: 2.746 ± 1.103
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.61TrpGlu: 0.61 ± 0.322
0.0TrpPhe: 0.0 ± 0.0
0.915TrpGly: 0.915 ± 0.484
0.305TrpHis: 0.305 ± 0.161
0.61TrpIle: 0.61 ± 1.078
0.61TrpLys: 0.61 ± 0.322
2.136TrpLeu: 2.136 ± 0.799
0.305TrpMet: 0.305 ± 0.161
0.915TrpAsn: 0.915 ± 0.785
0.61TrpPro: 0.61 ± 0.322
0.305TrpGln: 0.305 ± 0.161
0.305TrpArg: 0.305 ± 0.161
1.526TrpSer: 1.526 ± 0.457
1.526TrpThr: 1.526 ± 0.457
0.61TrpVal: 0.61 ± 0.351
0.915TrpTrp: 0.915 ± 0.785
0.305TrpTyr: 0.305 ± 0.161
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.052TyrAla: 3.052 ± 1.18
0.0TyrCys: 0.0 ± 0.0
1.831TyrAsp: 1.831 ± 0.672
1.221TyrGlu: 1.221 ± 0.645
1.831TyrPhe: 1.831 ± 0.485
3.357TyrGly: 3.357 ± 0.844
1.526TyrHis: 1.526 ± 0.186
2.746TyrIle: 2.746 ± 0.948
0.61TyrLys: 0.61 ± 0.351
3.662TyrLeu: 3.662 ± 0.504
0.915TyrMet: 0.915 ± 0.316
1.526TyrAsn: 1.526 ± 0.806
0.915TyrPro: 0.915 ± 0.316
1.831TyrGln: 1.831 ± 0.948
3.357TyrArg: 3.357 ± 1.336
4.883TyrSer: 4.883 ± 1.592
2.746TyrThr: 2.746 ± 0.577
3.662TyrVal: 3.662 ± 0.969
0.61TyrTrp: 0.61 ± 0.351
1.831TyrTyr: 1.831 ± 0.672
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (3278 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski