Amino acid dipepetide frequency for Globisporangium ultimum (strain ATCC 200006 / CBS 805.95 / DAOM BR144) (Pythium ultimum)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.493AlaAla: 10.493 ± 0.063
1.321AlaCys: 1.321 ± 0.017
4.357AlaAsp: 4.357 ± 0.031
4.784AlaGlu: 4.784 ± 0.031
3.543AlaPhe: 3.543 ± 0.023
4.709AlaGly: 4.709 ± 0.034
2.116AlaHis: 2.116 ± 0.019
4.323AlaIle: 4.323 ± 0.028
4.869AlaLys: 4.869 ± 0.035
8.768AlaLeu: 8.768 ± 0.047
2.43AlaMet: 2.43 ± 0.019
3.419AlaAsn: 3.419 ± 0.028
4.19AlaPro: 4.19 ± 0.033
3.73AlaGln: 3.73 ± 0.025
4.742AlaArg: 4.742 ± 0.03
8.164AlaSer: 8.164 ± 0.043
6.04AlaThr: 6.04 ± 0.035
5.988AlaVal: 5.988 ± 0.034
0.898AlaTrp: 0.898 ± 0.013
2.134AlaTyr: 2.134 ± 0.02
0.0AlaXaa: 0.0 ± 0.0
Cys
1.381CysAla: 1.381 ± 0.014
0.401CysCys: 0.401 ± 0.009
0.88CysAsp: 0.88 ± 0.013
0.902CysGlu: 0.902 ± 0.013
0.743CysPhe: 0.743 ± 0.011
1.198CysGly: 1.198 ± 0.016
0.39CysHis: 0.39 ± 0.008
0.833CysIle: 0.833 ± 0.012
0.721CysLys: 0.721 ± 0.013
1.338CysLeu: 1.338 ± 0.016
0.417CysMet: 0.417 ± 0.009
0.531CysAsn: 0.531 ± 0.009
0.725CysPro: 0.725 ± 0.016
0.538CysGln: 0.538 ± 0.009
0.891CysArg: 0.891 ± 0.013
1.263CysSer: 1.263 ± 0.016
0.965CysThr: 0.965 ± 0.014
1.263CysVal: 1.263 ± 0.015
0.213CysTrp: 0.213 ± 0.007
0.442CysTyr: 0.442 ± 0.009
0.0CysXaa: 0.0 ± 0.0
Asp
6.207AspAla: 6.207 ± 0.034
0.766AspCys: 0.766 ± 0.013
5.105AspAsp: 5.105 ± 0.045
4.838AspGlu: 4.838 ± 0.032
2.161AspPhe: 2.161 ± 0.023
3.915AspGly: 3.915 ± 0.03
1.263AspHis: 1.263 ± 0.014
2.621AspIle: 2.621 ± 0.022
2.371AspLys: 2.371 ± 0.022
4.672AspLeu: 4.672 ± 0.026
1.274AspMet: 1.274 ± 0.013
1.85AspAsn: 1.85 ± 0.018
2.487AspPro: 2.487 ± 0.024
1.845AspGln: 1.845 ± 0.017
2.596AspArg: 2.596 ± 0.023
3.771AspSer: 3.771 ± 0.025
2.823AspThr: 2.823 ± 0.019
4.21AspVal: 4.21 ± 0.024
0.6AspTrp: 0.6 ± 0.01
1.372AspTyr: 1.372 ± 0.016
0.0AspXaa: 0.0 ± 0.0
Glu
5.094GluAla: 5.094 ± 0.034
0.926GluCys: 0.926 ± 0.013
3.933GluAsp: 3.933 ± 0.028
5.137GluGlu: 5.137 ± 0.045
2.363GluPhe: 2.363 ± 0.021
2.884GluGly: 2.884 ± 0.02
1.569GluHis: 1.569 ± 0.017
3.244GluIle: 3.244 ± 0.023
3.944GluLys: 3.944 ± 0.039
6.274GluLeu: 6.274 ± 0.042
1.675GluMet: 1.675 ± 0.017
2.605GluAsn: 2.605 ± 0.024
2.103GluPro: 2.103 ± 0.021
2.905GluGln: 2.905 ± 0.026
3.903GluArg: 3.903 ± 0.031
4.444GluSer: 4.444 ± 0.028
3.333GluThr: 3.333 ± 0.028
3.656GluVal: 3.656 ± 0.028
0.828GluTrp: 0.828 ± 0.012
1.865GluTyr: 1.865 ± 0.018
0.0GluXaa: 0.0 ± 0.0
Phe
3.563PheAla: 3.563 ± 0.027
0.772PheCys: 0.772 ± 0.012
2.425PheAsp: 2.425 ± 0.022
2.344PheGlu: 2.344 ± 0.018
1.781PhePhe: 1.781 ± 0.02
2.759PheGly: 2.759 ± 0.026
1.092PheHis: 1.092 ± 0.014
1.668PheIle: 1.668 ± 0.014
1.565PheLys: 1.565 ± 0.018
3.87PheLeu: 3.87 ± 0.027
0.952PheMet: 0.952 ± 0.014
1.38PheAsn: 1.38 ± 0.016
1.73PhePro: 1.73 ± 0.019
1.696PheGln: 1.696 ± 0.016
2.127PheArg: 2.127 ± 0.019
3.046PheSer: 3.046 ± 0.022
2.205PheThr: 2.205 ± 0.022
3.149PheVal: 3.149 ± 0.026
0.497PheTrp: 0.497 ± 0.01
1.269PheTyr: 1.269 ± 0.015
0.0PheXaa: 0.0 ± 0.0
Gly
5.186GlyAla: 5.186 ± 0.031
1.049GlyCys: 1.049 ± 0.016
3.733GlyAsp: 3.733 ± 0.028
3.238GlyGlu: 3.238 ± 0.023
2.549GlyPhe: 2.549 ± 0.024
5.036GlyGly: 5.036 ± 0.057
1.503GlyHis: 1.503 ± 0.017
2.976GlyIle: 2.976 ± 0.025
3.314GlyLys: 3.314 ± 0.024
4.534GlyLeu: 4.534 ± 0.03
1.454GlyMet: 1.454 ± 0.015
2.535GlyAsn: 2.535 ± 0.024
1.826GlyPro: 1.826 ± 0.019
1.776GlyGln: 1.776 ± 0.017
2.979GlyArg: 2.979 ± 0.028
5.224GlySer: 5.224 ± 0.042
3.281GlyThr: 3.281 ± 0.029
4.308GlyVal: 4.308 ± 0.031
0.691GlyTrp: 0.691 ± 0.012
1.848GlyTyr: 1.848 ± 0.02
0.0GlyXaa: 0.0 ± 0.0
His
2.459HisAla: 2.459 ± 0.021
0.437HisCys: 0.437 ± 0.009
1.486HisAsp: 1.486 ± 0.019
1.709HisGlu: 1.709 ± 0.017
1.112HisPhe: 1.112 ± 0.013
1.762HisGly: 1.762 ± 0.018
1.045HisHis: 1.045 ± 0.017
1.088HisIle: 1.088 ± 0.012
1.038HisLys: 1.038 ± 0.014
2.369HisLeu: 2.369 ± 0.022
0.594HisMet: 0.594 ± 0.008
0.836HisAsn: 0.836 ± 0.01
1.26HisPro: 1.26 ± 0.014
1.144HisGln: 1.144 ± 0.014
1.541HisArg: 1.541 ± 0.018
1.823HisSer: 1.823 ± 0.016
1.275HisThr: 1.275 ± 0.014
1.972HisVal: 1.972 ± 0.02
0.312HisTrp: 0.312 ± 0.007
0.722HisTyr: 0.722 ± 0.011
0.0HisXaa: 0.0 ± 0.0
Ile
4.515IleAla: 4.515 ± 0.031
0.854IleCys: 0.854 ± 0.011
2.79IleAsp: 2.79 ± 0.023
2.939IleGlu: 2.939 ± 0.024
1.765IlePhe: 1.765 ± 0.018
2.852IleGly: 2.852 ± 0.024
1.159IleHis: 1.159 ± 0.016
1.93IleIle: 1.93 ± 0.02
2.133IleLys: 2.133 ± 0.02
4.144IleLeu: 4.144 ± 0.029
1.018IleMet: 1.018 ± 0.014
1.58IleAsn: 1.58 ± 0.017
2.251IlePro: 2.251 ± 0.021
2.031IleGln: 2.031 ± 0.019
2.564IleArg: 2.564 ± 0.018
3.368IleSer: 3.368 ± 0.025
2.525IleThr: 2.525 ± 0.024
3.664IleVal: 3.664 ± 0.023
0.528IleTrp: 0.528 ± 0.01
1.222IleTyr: 1.222 ± 0.014
0.0IleXaa: 0.0 ± 0.0
Lys
4.278LysAla: 4.278 ± 0.031
0.829LysCys: 0.829 ± 0.012
2.643LysAsp: 2.643 ± 0.026
3.441LysGlu: 3.441 ± 0.032
1.795LysPhe: 1.795 ± 0.017
2.332LysGly: 2.332 ± 0.023
1.44LysHis: 1.44 ± 0.015
2.361LysIle: 2.361 ± 0.02
4.388LysLys: 4.388 ± 0.043
4.989LysLeu: 4.989 ± 0.034
1.35LysMet: 1.35 ± 0.015
2.067LysAsn: 2.067 ± 0.02
2.136LysPro: 2.136 ± 0.021
2.693LysGln: 2.693 ± 0.023
3.803LysArg: 3.803 ± 0.03
3.799LysSer: 3.799 ± 0.028
3.045LysThr: 3.045 ± 0.023
3.123LysVal: 3.123 ± 0.025
0.755LysTrp: 0.755 ± 0.011
1.687LysTyr: 1.687 ± 0.019
0.0LysXaa: 0.0 ± 0.0
Leu
7.914LeuAla: 7.914 ± 0.04
1.567LeuCys: 1.567 ± 0.018
4.98LeuAsp: 4.98 ± 0.03
6.091LeuGlu: 6.091 ± 0.038
3.764LeuPhe: 3.764 ± 0.033
4.811LeuGly: 4.811 ± 0.032
2.772LeuHis: 2.772 ± 0.024
3.621LeuIle: 3.621 ± 0.027
4.79LeuLys: 4.79 ± 0.032
9.843LeuLeu: 9.843 ± 0.061
2.176LeuMet: 2.176 ± 0.019
3.244LeuAsn: 3.244 ± 0.026
4.433LeuPro: 4.433 ± 0.028
4.795LeuGln: 4.795 ± 0.036
6.04LeuArg: 6.04 ± 0.039
7.22LeuSer: 7.22 ± 0.043
4.868LeuThr: 4.868 ± 0.027
6.544LeuVal: 6.544 ± 0.043
1.035LeuTrp: 1.035 ± 0.013
2.437LeuTyr: 2.437 ± 0.02
0.0LeuXaa: 0.0 ± 0.0
Met
2.248MetAla: 2.248 ± 0.02
0.38MetCys: 0.38 ± 0.008
1.526MetAsp: 1.526 ± 0.017
1.682MetGlu: 1.682 ± 0.018
0.853MetPhe: 0.853 ± 0.011
1.361MetGly: 1.361 ± 0.014
0.643MetHis: 0.643 ± 0.011
1.095MetIle: 1.095 ± 0.014
1.489MetLys: 1.489 ± 0.016
2.416MetLeu: 2.416 ± 0.018
0.737MetMet: 0.737 ± 0.011
1.002MetAsn: 1.002 ± 0.013
1.011MetPro: 1.011 ± 0.013
1.141MetGln: 1.141 ± 0.014
1.46MetArg: 1.46 ± 0.015
1.815MetSer: 1.815 ± 0.018
1.479MetThr: 1.479 ± 0.018
1.57MetVal: 1.57 ± 0.015
0.297MetTrp: 0.297 ± 0.006
0.699MetTyr: 0.699 ± 0.011
0.0MetXaa: 0.0 ± 0.0
Asn
3.895AsnAla: 3.895 ± 0.028
0.594AsnCys: 0.594 ± 0.01
2.296AsnAsp: 2.296 ± 0.02
2.473AsnGlu: 2.473 ± 0.02
1.405AsnPhe: 1.405 ± 0.016
3.068AsnGly: 3.068 ± 0.026
0.887AsnHis: 0.887 ± 0.012
1.613AsnIle: 1.613 ± 0.017
1.671AsnLys: 1.671 ± 0.017
3.033AsnLeu: 3.033 ± 0.027
0.879AsnMet: 0.879 ± 0.011
1.573AsnAsn: 1.573 ± 0.02
1.827AsnPro: 1.827 ± 0.017
1.449AsnGln: 1.449 ± 0.017
1.87AsnArg: 1.87 ± 0.02
2.809AsnSer: 2.809 ± 0.024
1.922AsnThr: 1.922 ± 0.017
2.78AsnVal: 2.78 ± 0.022
0.413AsnTrp: 0.413 ± 0.008
0.995AsnTyr: 0.995 ± 0.011
0.0AsnXaa: 0.0 ± 0.0
Pro
3.932ProAla: 3.932 ± 0.031
0.528ProCys: 0.528 ± 0.011
2.08ProAsp: 2.08 ± 0.02
2.689ProGlu: 2.689 ± 0.021
1.734ProPhe: 1.734 ± 0.019
2.302ProGly: 2.302 ± 0.023
1.168ProHis: 1.168 ± 0.014
1.91ProIle: 1.91 ± 0.018
2.15ProLys: 2.15 ± 0.022
4.01ProLeu: 4.01 ± 0.028
1.066ProMet: 1.066 ± 0.015
1.6ProAsn: 1.6 ± 0.017
3.06ProPro: 3.06 ± 0.04
1.861ProGln: 1.861 ± 0.019
2.442ProArg: 2.442 ± 0.021
4.475ProSer: 4.475 ± 0.034
3.034ProThr: 3.034 ± 0.026
3.155ProVal: 3.155 ± 0.026
0.47ProTrp: 0.47 ± 0.009
1.04ProTyr: 1.04 ± 0.013
0.0ProXaa: 0.0 ± 0.0
Gln
3.163GlnAla: 3.163 ± 0.021
0.644GlnCys: 0.644 ± 0.01
2.05GlnAsp: 2.05 ± 0.018
2.782GlnGlu: 2.782 ± 0.026
1.62GlnPhe: 1.62 ± 0.015
1.818GlnGly: 1.818 ± 0.017
1.376GlnHis: 1.376 ± 0.018
1.951GlnIle: 1.951 ± 0.017
2.319GlnLys: 2.319 ± 0.02
4.52GlnLeu: 4.52 ± 0.036
1.149GlnMet: 1.149 ± 0.013
1.453GlnAsn: 1.453 ± 0.015
1.762GlnPro: 1.762 ± 0.019
3.513GlnGln: 3.513 ± 0.035
3.082GlnArg: 3.082 ± 0.027
3.034GlnSer: 3.034 ± 0.023
2.156GlnThr: 2.156 ± 0.017
2.823GlnVal: 2.823 ± 0.021
0.598GlnTrp: 0.598 ± 0.01
1.234GlnTyr: 1.234 ± 0.016
0.0GlnXaa: 0.0 ± 0.0
Arg
4.733ArgAla: 4.733 ± 0.03
0.903ArgCys: 0.903 ± 0.012
3.101ArgAsp: 3.101 ± 0.025
3.719ArgGlu: 3.719 ± 0.029
2.364ArgPhe: 2.364 ± 0.019
3.15ArgGly: 3.15 ± 0.029
1.621ArgHis: 1.621 ± 0.016
2.849ArgIle: 2.849 ± 0.02
3.566ArgLys: 3.566 ± 0.031
5.183ArgLeu: 5.183 ± 0.03
1.519ArgMet: 1.519 ± 0.016
2.204ArgAsn: 2.204 ± 0.018
2.131ArgPro: 2.131 ± 0.019
2.63ArgGln: 2.63 ± 0.025
4.371ArgArg: 4.371 ± 0.039
4.498ArgSer: 4.498 ± 0.033
2.876ArgThr: 2.876 ± 0.022
4.077ArgVal: 4.077 ± 0.029
0.715ArgTrp: 0.715 ± 0.011
1.524ArgTyr: 1.524 ± 0.015
0.0ArgXaa: 0.0 ± 0.0
Ser
7.326SerAla: 7.326 ± 0.042
1.173SerCys: 1.173 ± 0.015
4.33SerAsp: 4.33 ± 0.029
4.286SerGlu: 4.286 ± 0.031
3.211SerPhe: 3.211 ± 0.027
5.395SerGly: 5.395 ± 0.056
1.753SerHis: 1.753 ± 0.018
3.838SerIle: 3.838 ± 0.026
4.05SerLys: 4.05 ± 0.024
6.806SerLeu: 6.806 ± 0.035
2.041SerMet: 2.041 ± 0.017
3.183SerAsn: 3.183 ± 0.024
3.93SerPro: 3.93 ± 0.03
2.747SerGln: 2.747 ± 0.022
4.161SerArg: 4.161 ± 0.033
10.389SerSer: 10.389 ± 0.082
5.487SerThr: 5.487 ± 0.035
5.403SerVal: 5.403 ± 0.034
0.882SerTrp: 0.882 ± 0.011
1.978SerTyr: 1.978 ± 0.019
0.0SerXaa: 0.0 ± 0.0
Thr
5.18ThrAla: 5.18 ± 0.031
0.934ThrCys: 0.934 ± 0.013
2.586ThrAsp: 2.586 ± 0.021
3.003ThrGlu: 3.003 ± 0.023
2.289ThrPhe: 2.289 ± 0.023
3.379ThrGly: 3.379 ± 0.032
1.343ThrHis: 1.343 ± 0.015
2.879ThrIle: 2.879 ± 0.027
3.136ThrLys: 3.136 ± 0.024
5.346ThrLeu: 5.346 ± 0.034
1.459ThrMet: 1.459 ± 0.015
2.167ThrAsn: 2.167 ± 0.019
3.281ThrPro: 3.281 ± 0.029
2.246ThrGln: 2.246 ± 0.018
3.071ThrArg: 3.071 ± 0.025
5.337ThrSer: 5.337 ± 0.037
4.498ThrThr: 4.498 ± 0.041
3.59ThrVal: 3.59 ± 0.028
0.686ThrTrp: 0.686 ± 0.011
1.455ThrTyr: 1.455 ± 0.018
0.0ThrXaa: 0.0 ± 0.0
Val
6.465ValAla: 6.465 ± 0.034
1.218ValCys: 1.218 ± 0.015
4.141ValAsp: 4.141 ± 0.026
4.222ValGlu: 4.222 ± 0.027
3.019ValPhe: 3.019 ± 0.028
3.765ValGly: 3.765 ± 0.029
1.812ValHis: 1.812 ± 0.018
3.182ValIle: 3.182 ± 0.024
3.455ValLys: 3.455 ± 0.026
7.006ValLeu: 7.006 ± 0.035
1.655ValMet: 1.655 ± 0.017
2.606ValAsn: 2.606 ± 0.022
3.058ValPro: 3.058 ± 0.029
2.765ValGln: 2.765 ± 0.022
3.729ValArg: 3.729 ± 0.024
5.159ValSer: 5.159 ± 0.035
3.916ValThr: 3.916 ± 0.029
5.78ValVal: 5.78 ± 0.041
0.818ValTrp: 0.818 ± 0.014
1.998ValTyr: 1.998 ± 0.019
0.0ValXaa: 0.0 ± 0.0
Trp
0.694TrpAla: 0.694 ± 0.01
0.201TrpCys: 0.201 ± 0.006
0.637TrpAsp: 0.637 ± 0.014
0.646TrpGlu: 0.646 ± 0.01
0.52TrpPhe: 0.52 ± 0.01
0.635TrpGly: 0.635 ± 0.012
0.301TrpHis: 0.301 ± 0.007
0.669TrpIle: 0.669 ± 0.011
0.808TrpLys: 0.808 ± 0.013
1.206TrpLeu: 1.206 ± 0.017
0.373TrpMet: 0.373 ± 0.007
0.547TrpAsn: 0.547 ± 0.011
0.355TrpPro: 0.355 ± 0.008
0.475TrpGln: 0.475 ± 0.009
0.814TrpArg: 0.814 ± 0.013
0.919TrpSer: 0.919 ± 0.015
0.711TrpThr: 0.711 ± 0.011
0.723TrpVal: 0.723 ± 0.011
0.176TrpTrp: 0.176 ± 0.005
0.379TrpTyr: 0.379 ± 0.007
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.294TyrAla: 2.294 ± 0.02
0.536TyrCys: 0.536 ± 0.011
1.667TyrAsp: 1.667 ± 0.016
1.761TyrGlu: 1.761 ± 0.018
1.298TyrPhe: 1.298 ± 0.015
1.908TyrGly: 1.908 ± 0.024
0.733TyrHis: 0.733 ± 0.011
1.18TyrIle: 1.18 ± 0.013
1.181TyrLys: 1.181 ± 0.013
2.616TyrLeu: 2.616 ± 0.023
0.683TyrMet: 0.683 ± 0.01
1.071TyrAsn: 1.071 ± 0.014
1.15TyrPro: 1.15 ± 0.015
1.068TyrGln: 1.068 ± 0.012
1.549TyrArg: 1.549 ± 0.015
1.812TyrSer: 1.812 ± 0.017
1.427TyrThr: 1.427 ± 0.019
1.992TyrVal: 1.992 ± 0.019
0.374TyrTrp: 0.374 ± 0.008
0.926TyrTyr: 0.926 ± 0.014
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.008XaaXaa: 0.008 ± 0.003
Statistics based on 15153 proteins (6584968 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski