Amino acid dipepetide frequency for Cryphonectria hypovirus 4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.025AlaAla: 7.025 ± 0.0
1.054AlaCys: 1.054 ± 0.0
3.512AlaAsp: 3.512 ± 0.0
3.864AlaGlu: 3.864 ± 0.0
3.864AlaPhe: 3.864 ± 0.0
7.025AlaGly: 7.025 ± 0.0
3.161AlaHis: 3.161 ± 0.0
3.512AlaIle: 3.512 ± 0.0
4.215AlaLys: 4.215 ± 0.0
9.484AlaLeu: 9.484 ± 0.0
2.107AlaMet: 2.107 ± 0.0
2.107AlaAsn: 2.107 ± 0.0
4.566AlaPro: 4.566 ± 0.0
2.459AlaGln: 2.459 ± 0.0
5.62AlaArg: 5.62 ± 0.0
4.215AlaSer: 4.215 ± 0.0
4.215AlaThr: 4.215 ± 0.0
5.62AlaVal: 5.62 ± 0.0
3.512AlaTrp: 3.512 ± 0.0
2.459AlaTyr: 2.459 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.405CysAla: 1.405 ± 0.0
0.351CysCys: 0.351 ± 0.0
0.351CysAsp: 0.351 ± 0.0
1.405CysGlu: 1.405 ± 0.0
0.702CysPhe: 0.702 ± 0.0
1.405CysGly: 1.405 ± 0.0
1.054CysHis: 1.054 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.702CysLys: 0.702 ± 0.0
1.405CysLeu: 1.405 ± 0.0
0.351CysMet: 0.351 ± 0.0
0.351CysAsn: 0.351 ± 0.0
2.107CysPro: 2.107 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.405CysArg: 1.405 ± 0.0
0.351CysSer: 0.351 ± 0.0
1.054CysThr: 1.054 ± 0.0
2.459CysVal: 2.459 ± 0.0
0.702CysTrp: 0.702 ± 0.0
0.351CysTyr: 0.351 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.62AspAla: 5.62 ± 0.0
0.702AspCys: 0.702 ± 0.0
3.512AspAsp: 3.512 ± 0.0
2.459AspGlu: 2.459 ± 0.0
4.215AspPhe: 4.215 ± 0.0
2.107AspGly: 2.107 ± 0.0
1.405AspHis: 1.405 ± 0.0
1.756AspIle: 1.756 ± 0.0
1.756AspLys: 1.756 ± 0.0
8.079AspLeu: 8.079 ± 0.0
0.0AspMet: 0.0 ± 0.0
1.756AspAsn: 1.756 ± 0.0
3.512AspPro: 3.512 ± 0.0
2.81AspGln: 2.81 ± 0.0
2.81AspArg: 2.81 ± 0.0
3.512AspSer: 3.512 ± 0.0
2.459AspThr: 2.459 ± 0.0
5.269AspVal: 5.269 ± 0.0
2.107AspTrp: 2.107 ± 0.0
1.405AspTyr: 1.405 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
5.971GluAla: 5.971 ± 0.0
0.702GluCys: 0.702 ± 0.0
2.459GluAsp: 2.459 ± 0.0
2.81GluGlu: 2.81 ± 0.0
3.512GluPhe: 3.512 ± 0.0
6.322GluGly: 6.322 ± 0.0
2.459GluHis: 2.459 ± 0.0
1.405GluIle: 1.405 ± 0.0
2.459GluLys: 2.459 ± 0.0
6.322GluLeu: 6.322 ± 0.0
1.756GluMet: 1.756 ± 0.0
2.459GluAsn: 2.459 ± 0.0
1.756GluPro: 1.756 ± 0.0
1.756GluGln: 1.756 ± 0.0
4.917GluArg: 4.917 ± 0.0
2.107GluSer: 2.107 ± 0.0
1.756GluThr: 1.756 ± 0.0
5.269GluVal: 5.269 ± 0.0
2.107GluTrp: 2.107 ± 0.0
2.459GluTyr: 2.459 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
3.161PheAla: 3.161 ± 0.0
2.459PheCys: 2.459 ± 0.0
2.107PheAsp: 2.107 ± 0.0
2.459PheGlu: 2.459 ± 0.0
0.351PhePhe: 0.351 ± 0.0
4.917PheGly: 4.917 ± 0.0
1.054PheHis: 1.054 ± 0.0
2.107PheIle: 2.107 ± 0.0
2.459PheLys: 2.459 ± 0.0
3.161PheLeu: 3.161 ± 0.0
0.351PheMet: 0.351 ± 0.0
0.351PheAsn: 0.351 ± 0.0
4.215PhePro: 4.215 ± 0.0
1.054PheGln: 1.054 ± 0.0
3.864PheArg: 3.864 ± 0.0
5.62PheSer: 5.62 ± 0.0
1.405PheThr: 1.405 ± 0.0
2.107PheVal: 2.107 ± 0.0
2.107PheTrp: 2.107 ± 0.0
0.702PheTyr: 0.702 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
3.512GlyAla: 3.512 ± 0.0
1.405GlyCys: 1.405 ± 0.0
3.864GlyAsp: 3.864 ± 0.0
5.971GlyGlu: 5.971 ± 0.0
2.107GlyPhe: 2.107 ± 0.0
6.322GlyGly: 6.322 ± 0.0
1.756GlyHis: 1.756 ± 0.0
0.351GlyIle: 0.351 ± 0.0
4.215GlyLys: 4.215 ± 0.0
8.43GlyLeu: 8.43 ± 0.0
0.351GlyMet: 0.351 ± 0.0
1.405GlyAsn: 1.405 ± 0.0
4.566GlyPro: 4.566 ± 0.0
1.405GlyGln: 1.405 ± 0.0
6.674GlyArg: 6.674 ± 0.0
4.917GlySer: 4.917 ± 0.0
4.917GlyThr: 4.917 ± 0.0
7.025GlyVal: 7.025 ± 0.0
3.161GlyTrp: 3.161 ± 0.0
2.107GlyTyr: 2.107 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
2.459HisAla: 2.459 ± 0.0
0.702HisCys: 0.702 ± 0.0
1.756HisAsp: 1.756 ± 0.0
1.405HisGlu: 1.405 ± 0.0
1.756HisPhe: 1.756 ± 0.0
1.756HisGly: 1.756 ± 0.0
2.81HisHis: 2.81 ± 0.0
0.702HisIle: 0.702 ± 0.0
0.702HisLys: 0.702 ± 0.0
3.512HisLeu: 3.512 ± 0.0
0.351HisMet: 0.351 ± 0.0
0.702HisAsn: 0.702 ± 0.0
1.405HisPro: 1.405 ± 0.0
1.405HisGln: 1.405 ± 0.0
1.054HisArg: 1.054 ± 0.0
1.405HisSer: 1.405 ± 0.0
0.702HisThr: 0.702 ± 0.0
3.161HisVal: 3.161 ± 0.0
0.702HisTrp: 0.702 ± 0.0
2.107HisTyr: 2.107 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.756IleAla: 1.756 ± 0.0
0.351IleCys: 0.351 ± 0.0
1.405IleAsp: 1.405 ± 0.0
2.107IleGlu: 2.107 ± 0.0
1.405IlePhe: 1.405 ± 0.0
2.459IleGly: 2.459 ± 0.0
0.351IleHis: 0.351 ± 0.0
1.054IleIle: 1.054 ± 0.0
2.81IleLys: 2.81 ± 0.0
2.81IleLeu: 2.81 ± 0.0
0.351IleMet: 0.351 ± 0.0
2.107IleAsn: 2.107 ± 0.0
2.107IlePro: 2.107 ± 0.0
0.702IleGln: 0.702 ± 0.0
1.756IleArg: 1.756 ± 0.0
1.054IleSer: 1.054 ± 0.0
2.107IleThr: 2.107 ± 0.0
3.864IleVal: 3.864 ± 0.0
0.702IleTrp: 0.702 ± 0.0
0.351IleTyr: 0.351 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
3.512LysAla: 3.512 ± 0.0
1.054LysCys: 1.054 ± 0.0
1.756LysAsp: 1.756 ± 0.0
1.756LysGlu: 1.756 ± 0.0
2.107LysPhe: 2.107 ± 0.0
1.756LysGly: 1.756 ± 0.0
1.756LysHis: 1.756 ± 0.0
1.054LysIle: 1.054 ± 0.0
2.107LysLys: 2.107 ± 0.0
5.62LysLeu: 5.62 ± 0.0
0.351LysMet: 0.351 ± 0.0
1.054LysAsn: 1.054 ± 0.0
2.459LysPro: 2.459 ± 0.0
1.054LysGln: 1.054 ± 0.0
3.161LysArg: 3.161 ± 0.0
1.405LysSer: 1.405 ± 0.0
1.054LysThr: 1.054 ± 0.0
3.864LysVal: 3.864 ± 0.0
1.756LysTrp: 1.756 ± 0.0
1.054LysTyr: 1.054 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
9.835LeuAla: 9.835 ± 0.0
2.107LeuCys: 2.107 ± 0.0
6.322LeuAsp: 6.322 ± 0.0
6.674LeuGlu: 6.674 ± 0.0
3.864LeuPhe: 3.864 ± 0.0
7.025LeuGly: 7.025 ± 0.0
1.756LeuHis: 1.756 ± 0.0
3.161LeuIle: 3.161 ± 0.0
2.81LeuLys: 2.81 ± 0.0
6.322LeuLeu: 6.322 ± 0.0
1.405LeuMet: 1.405 ± 0.0
2.459LeuAsn: 2.459 ± 0.0
7.025LeuPro: 7.025 ± 0.0
3.512LeuGln: 3.512 ± 0.0
8.781LeuArg: 8.781 ± 0.0
8.079LeuSer: 8.079 ± 0.0
7.376LeuThr: 7.376 ± 0.0
8.079LeuVal: 8.079 ± 0.0
2.107LeuTrp: 2.107 ± 0.0
2.107LeuTyr: 2.107 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
1.405MetAla: 1.405 ± 0.0
1.054MetCys: 1.054 ± 0.0
1.405MetAsp: 1.405 ± 0.0
0.351MetGlu: 0.351 ± 0.0
0.702MetPhe: 0.702 ± 0.0
1.054MetGly: 1.054 ± 0.0
0.702MetHis: 0.702 ± 0.0
0.351MetIle: 0.351 ± 0.0
0.702MetLys: 0.702 ± 0.0
0.702MetLeu: 0.702 ± 0.0
0.702MetMet: 0.702 ± 0.0
0.351MetAsn: 0.351 ± 0.0
1.405MetPro: 1.405 ± 0.0
1.756MetGln: 1.756 ± 0.0
1.405MetArg: 1.405 ± 0.0
1.756MetSer: 1.756 ± 0.0
1.405MetThr: 1.405 ± 0.0
0.0MetVal: 0.0 ± 0.0
0.351MetTrp: 0.351 ± 0.0
0.702MetTyr: 0.702 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.107AsnAla: 2.107 ± 0.0
1.054AsnCys: 1.054 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
1.054AsnGlu: 1.054 ± 0.0
1.405AsnPhe: 1.405 ± 0.0
1.054AsnGly: 1.054 ± 0.0
0.351AsnHis: 0.351 ± 0.0
1.405AsnIle: 1.405 ± 0.0
0.702AsnLys: 0.702 ± 0.0
3.512AsnLeu: 3.512 ± 0.0
0.0AsnMet: 0.0 ± 0.0
0.351AsnAsn: 0.351 ± 0.0
1.756AsnPro: 1.756 ± 0.0
0.351AsnGln: 0.351 ± 0.0
2.459AsnArg: 2.459 ± 0.0
1.405AsnSer: 1.405 ± 0.0
2.459AsnThr: 2.459 ± 0.0
0.702AsnVal: 0.702 ± 0.0
0.702AsnTrp: 0.702 ± 0.0
0.351AsnTyr: 0.351 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.161ProAla: 3.161 ± 0.0
0.0ProCys: 0.0 ± 0.0
3.864ProAsp: 3.864 ± 0.0
7.727ProGlu: 7.727 ± 0.0
2.81ProPhe: 2.81 ± 0.0
5.971ProGly: 5.971 ± 0.0
0.702ProHis: 0.702 ± 0.0
1.756ProIle: 1.756 ± 0.0
1.756ProLys: 1.756 ± 0.0
5.62ProLeu: 5.62 ± 0.0
0.702ProMet: 0.702 ± 0.0
1.054ProAsn: 1.054 ± 0.0
4.215ProPro: 4.215 ± 0.0
3.161ProGln: 3.161 ± 0.0
3.512ProArg: 3.512 ± 0.0
2.459ProSer: 2.459 ± 0.0
3.864ProThr: 3.864 ± 0.0
6.322ProVal: 6.322 ± 0.0
2.107ProTrp: 2.107 ± 0.0
1.054ProTyr: 1.054 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
2.459GlnAla: 2.459 ± 0.0
0.702GlnCys: 0.702 ± 0.0
3.512GlnAsp: 3.512 ± 0.0
2.107GlnGlu: 2.107 ± 0.0
1.405GlnPhe: 1.405 ± 0.0
2.459GlnGly: 2.459 ± 0.0
0.0GlnHis: 0.0 ± 0.0
0.702GlnIle: 0.702 ± 0.0
1.054GlnLys: 1.054 ± 0.0
2.81GlnLeu: 2.81 ± 0.0
1.756GlnMet: 1.756 ± 0.0
0.351GlnAsn: 0.351 ± 0.0
1.405GlnPro: 1.405 ± 0.0
2.107GlnGln: 2.107 ± 0.0
3.512GlnArg: 3.512 ± 0.0
1.054GlnSer: 1.054 ± 0.0
1.054GlnThr: 1.054 ± 0.0
3.512GlnVal: 3.512 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
6.322ArgAla: 6.322 ± 0.0
0.351ArgCys: 0.351 ± 0.0
4.215ArgAsp: 4.215 ± 0.0
6.322ArgGlu: 6.322 ± 0.0
4.566ArgPhe: 4.566 ± 0.0
4.215ArgGly: 4.215 ± 0.0
3.512ArgHis: 3.512 ± 0.0
4.215ArgIle: 4.215 ± 0.0
2.459ArgLys: 2.459 ± 0.0
6.674ArgLeu: 6.674 ± 0.0
1.405ArgMet: 1.405 ± 0.0
1.405ArgAsn: 1.405 ± 0.0
3.161ArgPro: 3.161 ± 0.0
1.054ArgGln: 1.054 ± 0.0
7.025ArgArg: 7.025 ± 0.0
3.864ArgSer: 3.864 ± 0.0
4.215ArgThr: 4.215 ± 0.0
5.971ArgVal: 5.971 ± 0.0
2.459ArgTrp: 2.459 ± 0.0
2.107ArgTyr: 2.107 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
6.674SerAla: 6.674 ± 0.0
0.702SerCys: 0.702 ± 0.0
3.512SerAsp: 3.512 ± 0.0
2.81SerGlu: 2.81 ± 0.0
4.566SerPhe: 4.566 ± 0.0
3.864SerGly: 3.864 ± 0.0
2.107SerHis: 2.107 ± 0.0
1.756SerIle: 1.756 ± 0.0
0.351SerLys: 0.351 ± 0.0
7.376SerLeu: 7.376 ± 0.0
1.054SerMet: 1.054 ± 0.0
1.405SerAsn: 1.405 ± 0.0
3.512SerPro: 3.512 ± 0.0
1.756SerGln: 1.756 ± 0.0
3.512SerArg: 3.512 ± 0.0
3.512SerSer: 3.512 ± 0.0
4.215SerThr: 4.215 ± 0.0
3.161SerVal: 3.161 ± 0.0
0.702SerTrp: 0.702 ± 0.0
1.054SerTyr: 1.054 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
3.864ThrAla: 3.864 ± 0.0
1.405ThrCys: 1.405 ± 0.0
3.864ThrAsp: 3.864 ± 0.0
1.405ThrGlu: 1.405 ± 0.0
2.107ThrPhe: 2.107 ± 0.0
5.62ThrGly: 5.62 ± 0.0
0.702ThrHis: 0.702 ± 0.0
2.107ThrIle: 2.107 ± 0.0
2.459ThrLys: 2.459 ± 0.0
4.917ThrLeu: 4.917 ± 0.0
0.702ThrMet: 0.702 ± 0.0
0.702ThrAsn: 0.702 ± 0.0
5.62ThrPro: 5.62 ± 0.0
2.107ThrGln: 2.107 ± 0.0
3.864ThrArg: 3.864 ± 0.0
2.107ThrSer: 2.107 ± 0.0
3.161ThrThr: 3.161 ± 0.0
4.215ThrVal: 4.215 ± 0.0
0.351ThrTrp: 0.351 ± 0.0
3.512ThrTyr: 3.512 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
8.781ValAla: 8.781 ± 0.0
1.054ValCys: 1.054 ± 0.0
5.62ValAsp: 5.62 ± 0.0
5.971ValGlu: 5.971 ± 0.0
1.756ValPhe: 1.756 ± 0.0
6.322ValGly: 6.322 ± 0.0
2.107ValHis: 2.107 ± 0.0
2.107ValIle: 2.107 ± 0.0
2.459ValLys: 2.459 ± 0.0
7.025ValLeu: 7.025 ± 0.0
2.81ValMet: 2.81 ± 0.0
0.351ValAsn: 0.351 ± 0.0
5.971ValPro: 5.971 ± 0.0
1.756ValGln: 1.756 ± 0.0
5.971ValArg: 5.971 ± 0.0
4.215ValSer: 4.215 ± 0.0
4.917ValThr: 4.917 ± 0.0
5.971ValVal: 5.971 ± 0.0
2.107ValTrp: 2.107 ± 0.0
1.405ValTyr: 1.405 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
3.161TrpAla: 3.161 ± 0.0
0.702TrpCys: 0.702 ± 0.0
2.81TrpAsp: 2.81 ± 0.0
1.405TrpGlu: 1.405 ± 0.0
1.405TrpPhe: 1.405 ± 0.0
0.351TrpGly: 0.351 ± 0.0
1.756TrpHis: 1.756 ± 0.0
1.054TrpIle: 1.054 ± 0.0
1.405TrpLys: 1.405 ± 0.0
3.161TrpLeu: 3.161 ± 0.0
0.702TrpMet: 0.702 ± 0.0
1.756TrpAsn: 1.756 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.351TrpGln: 0.351 ± 0.0
2.459TrpArg: 2.459 ± 0.0
3.161TrpSer: 3.161 ± 0.0
1.054TrpThr: 1.054 ± 0.0
1.756TrpVal: 1.756 ± 0.0
0.702TrpTrp: 0.702 ± 0.0
0.351TrpTyr: 0.351 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.405TyrAla: 1.405 ± 0.0
0.0TyrCys: 0.0 ± 0.0
1.405TyrAsp: 1.405 ± 0.0
1.054TyrGlu: 1.054 ± 0.0
1.405TyrPhe: 1.405 ± 0.0
2.459TyrGly: 2.459 ± 0.0
1.054TyrHis: 1.054 ± 0.0
1.054TyrIle: 1.054 ± 0.0
2.107TyrLys: 2.107 ± 0.0
3.864TyrLeu: 3.864 ± 0.0
0.702TyrMet: 0.702 ± 0.0
0.702TyrAsn: 0.702 ± 0.0
1.054TyrPro: 1.054 ± 0.0
1.405TyrGln: 1.405 ± 0.0
1.756TyrArg: 1.756 ± 0.0
1.405TyrSer: 1.405 ± 0.0
1.405TyrThr: 1.405 ± 0.0
0.351TyrVal: 0.351 ± 0.0
1.054TyrTrp: 1.054 ± 0.0
0.351TyrTyr: 0.351 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (2848 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski