Amino acid dipepetide frequency for Raphanus sativas chrysovirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.165AlaAla: 2.165 ± 0.998
1.547AlaCys: 1.547 ± 0.293
4.021AlaAsp: 4.021 ± 0.176
4.64AlaGlu: 4.64 ± 0.689
1.547AlaPhe: 1.547 ± 0.637
4.021AlaGly: 4.021 ± 1.96
0.619AlaHis: 0.619 ± 0.247
3.093AlaIle: 3.093 ± 0.231
4.021AlaLys: 4.021 ± 1.296
7.114AlaLeu: 7.114 ± 1.203
2.165AlaMet: 2.165 ± 0.646
2.165AlaAsn: 2.165 ± 0.337
4.021AlaPro: 4.021 ± 1.714
3.402AlaGln: 3.402 ± 1.176
3.712AlaArg: 3.712 ± 0.466
4.021AlaSer: 4.021 ± 0.804
2.784AlaThr: 2.784 ± 0.806
2.784AlaVal: 2.784 ± 1.008
0.619AlaTrp: 0.619 ± 0.55
2.474AlaTyr: 2.474 ± 0.859
0.0AlaXaa: 0.0 ± 0.0
Cys
1.237CysAla: 1.237 ± 0.624
0.619CysCys: 0.619 ± 0.488
0.619CysAsp: 0.619 ± 0.244
0.619CysGlu: 0.619 ± 0.244
0.309CysPhe: 0.309 ± 0.275
0.619CysGly: 0.619 ± 0.268
0.309CysHis: 0.309 ± 0.244
0.0CysIle: 0.0 ± 0.0
0.619CysLys: 0.619 ± 0.268
2.784CysLeu: 2.784 ± 1.414
0.0CysMet: 0.0 ± 0.0
1.547CysAsn: 1.547 ± 0.261
0.928CysPro: 0.928 ± 0.407
0.928CysGln: 0.928 ± 0.414
0.619CysArg: 0.619 ± 0.474
2.165CysSer: 2.165 ± 0.203
0.928CysThr: 0.928 ± 0.032
1.856CysVal: 1.856 ± 0.436
0.0CysTrp: 0.0 ± 0.0
0.619CysTyr: 0.619 ± 0.247
0.0CysXaa: 0.0 ± 0.0
Asp
3.093AspAla: 3.093 ± 0.809
0.619AspCys: 0.619 ± 0.247
4.64AspAsp: 4.64 ± 0.64
4.64AspGlu: 4.64 ± 0.483
3.712AspPhe: 3.712 ± 0.671
5.568AspGly: 5.568 ± 2.301
2.165AspHis: 2.165 ± 0.457
1.856AspIle: 1.856 ± 0.396
4.33AspLys: 4.33 ± 0.317
8.351AspLeu: 8.351 ± 0.577
1.856AspMet: 1.856 ± 0.34
2.474AspAsn: 2.474 ± 0.768
1.856AspPro: 1.856 ± 0.402
0.928AspGln: 0.928 ± 0.462
2.784AspArg: 2.784 ± 0.697
4.949AspSer: 4.949 ± 0.249
3.402AspThr: 3.402 ± 1.096
5.877AspVal: 5.877 ± 0.673
1.547AspTrp: 1.547 ± 0.213
2.165AspTyr: 2.165 ± 0.612
0.0AspXaa: 0.0 ± 0.0
Glu
4.949GluAla: 4.949 ± 0.923
1.547GluCys: 1.547 ± 0.651
3.712GluAsp: 3.712 ± 1.086
5.258GluGlu: 5.258 ± 1.026
3.093GluPhe: 3.093 ± 0.932
3.712GluGly: 3.712 ± 0.399
0.928GluHis: 0.928 ± 0.407
3.093GluIle: 3.093 ± 1.712
4.64GluLys: 4.64 ± 0.306
5.877GluLeu: 5.877 ± 1.087
3.402GluMet: 3.402 ± 0.632
2.474GluAsn: 2.474 ± 0.445
1.547GluPro: 1.547 ± 0.856
0.928GluGln: 0.928 ± 0.427
3.712GluArg: 3.712 ± 1.872
3.712GluSer: 3.712 ± 1.21
3.093GluThr: 3.093 ± 0.601
6.805GluVal: 6.805 ± 1.607
1.547GluTrp: 1.547 ± 0.213
3.093GluTyr: 3.093 ± 1.316
0.0GluXaa: 0.0 ± 0.0
Phe
0.928PheAla: 0.928 ± 0.032
1.856PheCys: 1.856 ± 0.854
2.784PheAsp: 2.784 ± 0.701
3.712PheGlu: 3.712 ± 0.792
0.309PhePhe: 0.309 ± 0.275
0.928PheGly: 0.928 ± 0.032
0.928PheHis: 0.928 ± 0.427
0.928PheIle: 0.928 ± 0.488
1.237PheLys: 1.237 ± 0.488
3.093PheLeu: 3.093 ± 0.944
1.547PheMet: 1.547 ± 0.466
1.547PheAsn: 1.547 ± 0.581
0.619PhePro: 0.619 ± 0.247
2.165PheGln: 2.165 ± 0.94
2.165PheArg: 2.165 ± 0.561
3.093PheSer: 3.093 ± 0.188
2.165PheThr: 2.165 ± 0.229
3.093PheVal: 3.093 ± 1.044
0.619PheTrp: 0.619 ± 0.244
1.237PheTyr: 1.237 ± 0.624
0.0PheXaa: 0.0 ± 0.0
Gly
6.805GlyAla: 6.805 ± 1.843
1.237GlyCys: 1.237 ± 0.231
5.568GlyAsp: 5.568 ± 1.462
7.114GlyGlu: 7.114 ± 1.65
1.237GlyPhe: 1.237 ± 0.488
7.114GlyGly: 7.114 ± 0.461
2.165GlyHis: 2.165 ± 0.457
2.474GlyIle: 2.474 ± 0.612
4.021GlyLys: 4.021 ± 0.396
6.496GlyLeu: 6.496 ± 0.814
1.547GlyMet: 1.547 ± 0.293
2.474GlyAsn: 2.474 ± 0.445
0.619GlyPro: 0.619 ± 0.268
1.237GlyGln: 1.237 ± 0.536
7.114GlyArg: 7.114 ± 0.826
5.258GlySer: 5.258 ± 1.212
3.093GlyThr: 3.093 ± 0.809
5.877GlyVal: 5.877 ± 1.255
1.237GlyTrp: 1.237 ± 0.222
3.402GlyTyr: 3.402 ± 1.0
0.0GlyXaa: 0.0 ± 0.0
His
2.474HisAla: 2.474 ± 0.462
0.619HisCys: 0.619 ± 0.474
0.309HisAsp: 0.309 ± 0.237
1.237HisGlu: 1.237 ± 0.488
0.309HisPhe: 0.309 ± 0.244
2.165HisGly: 2.165 ± 0.862
1.237HisHis: 1.237 ± 0.624
1.547HisIle: 1.547 ± 0.293
0.309HisLys: 0.309 ± 0.237
1.856HisLeu: 1.856 ± 0.064
0.928HisMet: 0.928 ± 0.407
1.856HisAsn: 1.856 ± 0.396
0.309HisPro: 0.309 ± 0.275
0.928HisGln: 0.928 ± 0.425
0.619HisArg: 0.619 ± 0.488
2.474HisSer: 2.474 ± 0.629
0.0HisThr: 0.0 ± 0.0
1.856HisVal: 1.856 ± 0.71
1.237HisTrp: 1.237 ± 0.651
0.928HisTyr: 0.928 ± 0.462
0.0HisXaa: 0.0 ± 0.0
Ile
2.474IleAla: 2.474 ± 0.686
0.619IleCys: 0.619 ± 0.268
2.784IleAsp: 2.784 ± 1.085
3.712IleGlu: 3.712 ± 0.692
1.856IlePhe: 1.856 ± 0.402
3.402IleGly: 3.402 ± 0.632
0.309IleHis: 0.309 ± 0.244
0.928IleIle: 0.928 ± 0.414
2.474IleLys: 2.474 ± 0.277
4.949IleLeu: 4.949 ± 0.833
1.856IleMet: 1.856 ± 0.71
2.165IleAsn: 2.165 ± 0.954
2.784IlePro: 2.784 ± 0.366
0.928IleGln: 0.928 ± 0.407
3.093IleArg: 3.093 ± 0.844
4.021IleSer: 4.021 ± 0.396
1.856IleThr: 1.856 ± 0.396
3.093IleVal: 3.093 ± 0.188
0.619IleTrp: 0.619 ± 0.244
1.237IleTyr: 1.237 ± 0.624
0.0IleXaa: 0.0 ± 0.0
Lys
3.712LysAla: 3.712 ± 1.221
0.309LysCys: 0.309 ± 0.275
3.402LysAsp: 3.402 ± 0.459
2.474LysGlu: 2.474 ± 0.619
2.784LysPhe: 2.784 ± 0.55
3.402LysGly: 3.402 ± 0.643
2.165LysHis: 2.165 ± 0.337
3.093LysIle: 3.093 ± 1.34
3.712LysLys: 3.712 ± 0.336
4.64LysLeu: 4.64 ± 0.567
3.093LysMet: 3.093 ± 0.188
1.547LysAsn: 1.547 ± 0.293
1.547LysPro: 1.547 ± 0.467
1.856LysGln: 1.856 ± 0.396
2.474LysArg: 2.474 ± 0.277
2.784LysSer: 2.784 ± 0.806
1.856LysThr: 1.856 ± 0.732
4.021LysVal: 4.021 ± 1.664
0.309LysTrp: 0.309 ± 0.237
1.856LysTyr: 1.856 ± 0.064
0.0LysXaa: 0.0 ± 0.0
Leu
7.114LeuAla: 7.114 ± 1.058
1.237LeuCys: 1.237 ± 0.488
7.114LeuAsp: 7.114 ± 1.479
6.496LeuGlu: 6.496 ± 0.701
2.165LeuPhe: 2.165 ± 0.203
6.496LeuGly: 6.496 ± 1.389
1.856LeuHis: 1.856 ± 0.392
3.712LeuIle: 3.712 ± 0.336
6.186LeuLys: 6.186 ± 0.433
8.042LeuLeu: 8.042 ± 2.587
2.784LeuMet: 2.784 ± 0.095
4.021LeuAsn: 4.021 ± 1.247
6.186LeuPro: 6.186 ± 1.173
1.856LeuGln: 1.856 ± 0.402
7.423LeuArg: 7.423 ± 1.62
5.877LeuSer: 5.877 ± 0.666
5.877LeuThr: 5.877 ± 0.673
6.496LeuVal: 6.496 ± 0.623
0.619LeuTrp: 0.619 ± 0.247
2.474LeuTyr: 2.474 ± 1.047
0.0LeuXaa: 0.0 ± 0.0
Met
2.474MetAla: 2.474 ± 1.198
0.928MetCys: 0.928 ± 0.414
3.402MetAsp: 3.402 ± 0.347
2.784MetGlu: 2.784 ± 0.45
0.928MetPhe: 0.928 ± 0.462
4.021MetGly: 4.021 ± 0.964
0.928MetHis: 0.928 ± 0.407
2.165MetIle: 2.165 ± 0.623
1.856MetLys: 1.856 ± 0.703
1.547MetLeu: 1.547 ± 0.637
2.474MetMet: 2.474 ± 0.462
3.093MetAsn: 3.093 ± 1.314
1.547MetPro: 1.547 ± 0.213
0.309MetGln: 0.309 ± 0.237
1.547MetArg: 1.547 ± 0.637
2.474MetSer: 2.474 ± 1.072
0.928MetThr: 0.928 ± 0.732
1.547MetVal: 1.547 ± 0.261
0.619MetTrp: 0.619 ± 0.247
1.856MetTyr: 1.856 ± 0.402
0.0MetXaa: 0.0 ± 0.0
Asn
3.402AsnAla: 3.402 ± 1.044
0.619AsnCys: 0.619 ± 0.247
2.784AsnAsp: 2.784 ± 0.371
4.33AsnGlu: 4.33 ± 1.931
2.474AsnPhe: 2.474 ± 0.619
0.928AsnGly: 0.928 ± 0.462
1.547AsnHis: 1.547 ± 0.628
3.402AsnIle: 3.402 ± 0.347
2.474AsnLys: 2.474 ± 1.073
4.949AsnLeu: 4.949 ± 1.78
1.237AsnMet: 1.237 ± 0.231
2.165AsnAsn: 2.165 ± 0.927
2.474AsnPro: 2.474 ± 0.32
0.619AsnGln: 0.619 ± 0.244
3.093AsnArg: 3.093 ± 0.775
1.547AsnSer: 1.547 ± 0.467
1.547AsnThr: 1.547 ± 0.213
4.021AsnVal: 4.021 ± 0.176
0.309AsnTrp: 0.309 ± 0.244
1.547AsnTyr: 1.547 ± 1.013
0.0AsnXaa: 0.0 ± 0.0
Pro
3.093ProAla: 3.093 ± 0.933
0.309ProCys: 0.309 ± 0.237
2.474ProAsp: 2.474 ± 1.198
1.547ProGlu: 1.547 ± 0.581
0.928ProPhe: 0.928 ± 0.425
4.33ProGly: 4.33 ± 0.674
0.619ProHis: 0.619 ± 0.268
1.547ProIle: 1.547 ± 0.669
2.165ProLys: 2.165 ± 0.229
1.856ProLeu: 1.856 ± 1.086
1.237ProMet: 1.237 ± 0.306
2.784ProAsn: 2.784 ± 1.286
2.784ProPro: 2.784 ± 1.085
2.165ProGln: 2.165 ± 0.623
3.093ProArg: 3.093 ± 0.521
2.784ProSer: 2.784 ± 0.828
2.474ProThr: 2.474 ± 0.686
3.093ProVal: 3.093 ± 0.595
0.309ProTrp: 0.309 ± 0.244
1.856ProTyr: 1.856 ± 0.392
0.0ProXaa: 0.0 ± 0.0
Gln
0.309GlnAla: 0.309 ± 0.237
0.0GlnCys: 0.0 ± 0.0
1.856GlnAsp: 1.856 ± 0.856
2.165GlnGlu: 2.165 ± 0.229
0.619GlnPhe: 0.619 ± 0.488
1.237GlnGly: 1.237 ± 0.651
1.237GlnHis: 1.237 ± 0.651
0.619GlnIle: 0.619 ± 0.474
2.165GlnLys: 2.165 ± 0.337
2.784GlnLeu: 2.784 ± 0.095
1.237GlnMet: 1.237 ± 0.651
1.237GlnAsn: 1.237 ± 0.231
0.928GlnPro: 0.928 ± 0.425
0.619GlnGln: 0.619 ± 0.244
0.928GlnArg: 0.928 ± 0.032
2.474GlnSer: 2.474 ± 0.183
0.309GlnThr: 0.309 ± 0.275
1.547GlnVal: 1.547 ± 0.293
0.928GlnTrp: 0.928 ± 0.427
1.547GlnTyr: 1.547 ± 0.886
0.0GlnXaa: 0.0 ± 0.0
Arg
4.021ArgAla: 4.021 ± 0.238
1.547ArgCys: 1.547 ± 0.738
5.568ArgAsp: 5.568 ± 1.253
3.093ArgGlu: 3.093 ± 1.499
2.165ArgPhe: 2.165 ± 0.612
8.661ArgGly: 8.661 ± 2.23
2.165ArgHis: 2.165 ± 0.747
1.856ArgIle: 1.856 ± 0.854
1.237ArgLys: 1.237 ± 0.977
5.568ArgLeu: 5.568 ± 1.205
2.165ArgMet: 2.165 ± 0.337
2.784ArgAsn: 2.784 ± 1.085
3.712ArgPro: 3.712 ± 0.692
2.165ArgGln: 2.165 ± 0.337
5.568ArgArg: 5.568 ± 0.406
4.021ArgSer: 4.021 ± 0.612
2.165ArgThr: 2.165 ± 0.778
5.258ArgVal: 5.258 ± 1.497
1.856ArgTrp: 1.856 ± 1.093
2.784ArgTyr: 2.784 ± 1.085
0.0ArgXaa: 0.0 ± 0.0
Ser
3.402SerAla: 3.402 ± 1.076
1.237SerCys: 1.237 ± 0.231
3.402SerAsp: 3.402 ± 1.437
2.784SerGlu: 2.784 ± 0.688
3.402SerPhe: 3.402 ± 0.153
7.114SerGly: 7.114 ± 1.17
0.928SerHis: 0.928 ± 0.032
3.712SerIle: 3.712 ± 0.466
3.402SerLys: 3.402 ± 1.103
6.186SerLeu: 6.186 ± 1.171
3.093SerMet: 3.093 ± 0.427
2.165SerAsn: 2.165 ± 0.507
2.784SerPro: 2.784 ± 0.095
1.237SerGln: 1.237 ± 0.222
6.805SerArg: 6.805 ± 0.936
4.021SerSer: 4.021 ± 0.567
3.712SerThr: 3.712 ± 0.336
4.33SerVal: 4.33 ± 0.56
0.928SerTrp: 0.928 ± 0.427
3.093SerTyr: 3.093 ± 0.932
0.0SerXaa: 0.0 ± 0.0
Thr
2.784ThrAla: 2.784 ± 0.697
0.309ThrCys: 0.309 ± 0.237
4.33ThrAsp: 4.33 ± 1.121
1.547ThrGlu: 1.547 ± 0.213
1.856ThrPhe: 1.856 ± 0.487
3.402ThrGly: 3.402 ± 0.296
0.928ThrHis: 0.928 ± 0.711
1.856ThrIle: 1.856 ± 0.519
1.547ThrLys: 1.547 ± 0.213
5.258ThrLeu: 5.258 ± 0.779
1.856ThrMet: 1.856 ± 1.087
0.928ThrAsn: 0.928 ± 0.425
1.856ThrPro: 1.856 ± 0.487
0.619ThrGln: 0.619 ± 0.474
3.093ThrArg: 3.093 ± 0.595
3.402ThrSer: 3.402 ± 0.732
2.474ThrThr: 2.474 ± 0.183
5.258ThrVal: 5.258 ± 0.39
1.547ThrTrp: 1.547 ± 0.628
0.928ThrTyr: 0.928 ± 0.425
0.0ThrXaa: 0.0 ± 0.0
Val
4.949ValAla: 4.949 ± 0.89
0.928ValCys: 0.928 ± 0.462
4.949ValAsp: 4.949 ± 0.982
4.949ValGlu: 4.949 ± 0.982
2.474ValPhe: 2.474 ± 0.445
6.496ValGly: 6.496 ± 0.996
1.237ValHis: 1.237 ± 0.222
6.496ValIle: 6.496 ± 0.996
1.856ValLys: 1.856 ± 0.392
7.114ValLeu: 7.114 ± 0.461
3.402ValMet: 3.402 ± 1.073
4.64ValAsn: 4.64 ± 0.306
3.093ValPro: 3.093 ± 0.586
1.237ValGln: 1.237 ± 0.306
5.568ValArg: 5.568 ± 1.253
4.949ValSer: 4.949 ± 0.873
3.402ValThr: 3.402 ± 0.705
7.423ValVal: 7.423 ± 1.407
0.928ValTrp: 0.928 ± 0.414
2.474ValTyr: 2.474 ± 0.611
0.0ValXaa: 0.0 ± 0.0
Trp
0.619TrpAla: 0.619 ± 0.247
0.619TrpCys: 0.619 ± 0.247
0.309TrpAsp: 0.309 ± 0.237
1.237TrpGlu: 1.237 ± 0.222
0.928TrpPhe: 0.928 ± 0.732
0.309TrpGly: 0.309 ± 0.244
0.309TrpHis: 0.309 ± 0.237
0.928TrpIle: 0.928 ± 0.407
1.237TrpLys: 1.237 ± 0.222
1.856TrpLeu: 1.856 ± 0.854
0.0TrpMet: 0.0 ± 0.0
1.237TrpAsn: 1.237 ± 0.488
0.309TrpPro: 0.309 ± 0.237
0.0TrpGln: 0.0 ± 0.0
1.856TrpArg: 1.856 ± 0.519
0.619TrpSer: 0.619 ± 0.488
1.237TrpThr: 1.237 ± 0.222
1.237TrpVal: 1.237 ± 0.222
0.309TrpTrp: 0.309 ± 0.237
0.928TrpTyr: 0.928 ± 0.732
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.928TyrAla: 0.928 ± 0.711
0.619TyrCys: 0.619 ± 0.244
2.784TyrAsp: 2.784 ± 0.366
2.784TyrGlu: 2.784 ± 1.442
1.856TyrPhe: 1.856 ± 0.436
2.165TyrGly: 2.165 ± 1.025
0.619TyrHis: 0.619 ± 0.247
1.856TyrIle: 1.856 ± 0.703
1.547TyrLys: 1.547 ± 0.466
3.712TyrLeu: 3.712 ± 0.352
1.237TyrMet: 1.237 ± 0.624
2.165TyrAsn: 2.165 ± 0.998
1.547TyrPro: 1.547 ± 0.738
0.619TyrGln: 0.619 ± 0.247
3.093TyrArg: 3.093 ± 0.427
3.093TyrSer: 3.093 ± 0.188
2.474TyrThr: 2.474 ± 0.462
3.402TyrVal: 3.402 ± 1.498
0.0TyrTrp: 0.0 ± 0.0
1.237TyrTyr: 1.237 ± 0.651
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (3234 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski