Amino acid dipepetide frequency for Vernonia crinkle virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.559AlaAla: 3.559 ± 1.705
1.779AlaCys: 1.779 ± 1.527
0.0AlaAsp: 0.0 ± 0.0
3.559AlaGlu: 3.559 ± 1.538
1.779AlaPhe: 1.779 ± 0.973
0.89AlaGly: 0.89 ± 1.002
1.779AlaHis: 1.779 ± 1.797
3.559AlaIle: 3.559 ± 1.796
2.669AlaLys: 2.669 ± 0.906
7.117AlaLeu: 7.117 ± 3.065
0.89AlaMet: 0.89 ± 1.002
2.669AlaAsn: 2.669 ± 1.282
2.669AlaPro: 2.669 ± 1.497
4.448AlaGln: 4.448 ± 1.16
6.228AlaArg: 6.228 ± 2.294
5.338AlaSer: 5.338 ± 1.77
0.89AlaThr: 0.89 ± 0.763
0.89AlaVal: 0.89 ± 0.898
0.89AlaTrp: 0.89 ± 0.596
1.779AlaTyr: 1.779 ± 0.973
0.0AlaXaa: 0.0 ± 0.0
Cys
1.779CysAla: 1.779 ± 0.973
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.779CysGlu: 1.779 ± 1.066
0.89CysPhe: 0.89 ± 1.002
1.779CysGly: 1.779 ± 0.973
0.0CysHis: 0.0 ± 0.0
0.89CysIle: 0.89 ± 0.763
1.779CysLys: 1.779 ± 1.527
1.779CysLeu: 1.779 ± 1.089
0.89CysMet: 0.89 ± 0.763
1.779CysAsn: 1.779 ± 0.973
0.89CysPro: 0.89 ± 0.898
1.779CysGln: 1.779 ± 0.883
2.669CysArg: 2.669 ± 1.282
3.559CysSer: 3.559 ± 1.538
0.89CysThr: 0.89 ± 0.763
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.779AspAla: 1.779 ± 1.191
0.0AspCys: 0.0 ± 0.0
1.779AspAsp: 1.779 ± 1.146
1.779AspGlu: 1.779 ± 0.805
3.559AspPhe: 3.559 ± 1.614
1.779AspGly: 1.779 ± 1.191
1.779AspHis: 1.779 ± 0.973
3.559AspIle: 3.559 ± 1.366
0.0AspLys: 0.0 ± 0.0
4.448AspLeu: 4.448 ± 2.173
1.779AspMet: 1.779 ± 0.86
0.89AspAsn: 0.89 ± 0.763
1.779AspPro: 1.779 ± 0.883
1.779AspGln: 1.779 ± 1.066
2.669AspArg: 2.669 ± 1.451
4.448AspSer: 4.448 ± 2.14
4.448AspThr: 4.448 ± 1.954
5.338AspVal: 5.338 ± 1.688
1.779AspTrp: 1.779 ± 0.973
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
6.228GluAla: 6.228 ± 3.205
0.0GluCys: 0.0 ± 0.0
1.779GluAsp: 1.779 ± 0.973
5.338GluGlu: 5.338 ± 3.047
2.669GluPhe: 2.669 ± 1.497
2.669GluGly: 2.669 ± 1.193
1.779GluHis: 1.779 ± 0.926
0.0GluIle: 0.0 ± 0.0
4.448GluLys: 4.448 ± 1.603
3.559GluLeu: 3.559 ± 2.006
0.0GluMet: 0.0 ± 0.0
5.338GluAsn: 5.338 ± 2.069
4.448GluPro: 4.448 ± 0.935
3.559GluGln: 3.559 ± 1.366
0.0GluArg: 0.0 ± 0.0
2.669GluSer: 2.669 ± 1.811
2.669GluThr: 2.669 ± 2.111
2.669GluVal: 2.669 ± 1.4
1.779GluTrp: 1.779 ± 0.973
0.89GluTyr: 0.89 ± 1.002
0.0GluXaa: 0.0 ± 0.0
Phe
0.89PheAla: 0.89 ± 0.596
0.89PheCys: 0.89 ± 0.898
4.448PheAsp: 4.448 ± 2.097
0.89PheGlu: 0.89 ± 0.596
1.779PhePhe: 1.779 ± 1.191
1.779PheGly: 1.779 ± 1.066
2.669PheHis: 2.669 ± 1.787
2.669PheIle: 2.669 ± 1.183
3.559PheLys: 3.559 ± 1.098
7.117PheLeu: 7.117 ± 2.202
0.89PheMet: 0.89 ± 0.596
5.338PheAsn: 5.338 ± 1.739
0.89PhePro: 0.89 ± 0.898
0.89PheGln: 0.89 ± 0.596
1.779PheArg: 1.779 ± 1.066
2.669PheSer: 2.669 ± 1.364
3.559PheThr: 3.559 ± 2.813
1.779PheVal: 1.779 ± 0.883
0.89PheTrp: 0.89 ± 0.763
1.779PheTyr: 1.779 ± 0.985
0.0PheXaa: 0.0 ± 0.0
Gly
2.669GlyAla: 2.669 ± 1.787
2.669GlyCys: 2.669 ± 0.818
1.779GlyAsp: 1.779 ± 1.191
3.559GlyGlu: 3.559 ± 2.007
1.779GlyPhe: 1.779 ± 1.275
2.669GlyGly: 2.669 ± 1.193
1.779GlyHis: 1.779 ± 0.883
1.779GlyIle: 1.779 ± 0.926
4.448GlyLys: 4.448 ± 1.946
4.448GlyLeu: 4.448 ± 2.17
0.0GlyMet: 0.0 ± 0.0
2.669GlyAsn: 2.669 ± 1.277
4.448GlyPro: 4.448 ± 1.459
0.89GlyGln: 0.89 ± 0.763
1.779GlyArg: 1.779 ± 0.883
1.779GlySer: 1.779 ± 0.805
3.559GlyThr: 3.559 ± 1.884
0.89GlyVal: 0.89 ± 0.596
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.89HisAla: 0.89 ± 0.763
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.779HisGlu: 1.779 ± 0.973
2.669HisPhe: 2.669 ± 1.183
2.669HisGly: 2.669 ± 1.109
2.669HisHis: 2.669 ± 1.331
0.0HisIle: 0.0 ± 0.0
1.779HisLys: 1.779 ± 2.005
4.448HisLeu: 4.448 ± 1.433
0.89HisMet: 0.89 ± 1.046
5.338HisAsn: 5.338 ± 2.42
0.89HisPro: 0.89 ± 0.596
2.669HisGln: 2.669 ± 0.818
3.559HisArg: 3.559 ± 1.998
1.779HisSer: 1.779 ± 1.452
5.338HisThr: 5.338 ± 1.77
4.448HisVal: 4.448 ± 1.906
0.0HisTrp: 0.0 ± 0.0
1.779HisTyr: 1.779 ± 0.973
0.0HisXaa: 0.0 ± 0.0
Ile
1.779IleAla: 1.779 ± 1.452
1.779IleCys: 1.779 ± 0.883
2.669IleAsp: 2.669 ± 1.282
0.0IleGlu: 0.0 ± 0.0
1.779IlePhe: 1.779 ± 1.191
0.89IleGly: 0.89 ± 0.763
1.779IleHis: 1.779 ± 1.406
1.779IleIle: 1.779 ± 0.805
4.448IleLys: 4.448 ± 0.935
3.559IleLeu: 3.559 ± 1.413
2.669IleMet: 2.669 ± 1.631
4.448IleAsn: 4.448 ± 3.973
2.669IlePro: 2.669 ± 0.906
6.228IleGln: 6.228 ± 1.122
6.228IleArg: 6.228 ± 1.601
2.669IleSer: 2.669 ± 1.451
2.669IleThr: 2.669 ± 1.183
2.669IleVal: 2.669 ± 2.041
2.669IleTrp: 2.669 ± 2.041
4.448IleTyr: 4.448 ± 2.061
0.0IleXaa: 0.0 ± 0.0
Lys
2.669LysAla: 2.669 ± 1.21
2.669LysCys: 2.669 ± 1.183
2.669LysAsp: 2.669 ± 1.192
5.338LysGlu: 5.338 ± 2.272
3.559LysPhe: 3.559 ± 1.474
1.779LysGly: 1.779 ± 0.883
0.89LysHis: 0.89 ± 0.596
5.338LysIle: 5.338 ± 1.863
3.559LysLys: 3.559 ± 1.998
0.89LysLeu: 0.89 ± 0.596
0.89LysMet: 0.89 ± 1.046
2.669LysAsn: 2.669 ± 1.193
1.779LysPro: 1.779 ± 0.805
0.89LysGln: 0.89 ± 0.898
3.559LysArg: 3.559 ± 1.652
4.448LysSer: 4.448 ± 1.946
2.669LysThr: 2.669 ± 1.154
1.779LysVal: 1.779 ± 1.527
0.0LysTrp: 0.0 ± 0.0
5.338LysTyr: 5.338 ± 1.623
0.0LysXaa: 0.0 ± 0.0
Leu
2.669LeuAla: 2.669 ± 1.364
3.559LeuCys: 3.559 ± 1.102
6.228LeuAsp: 6.228 ± 3.394
7.117LeuGlu: 7.117 ± 3.157
2.669LeuPhe: 2.669 ± 1.787
1.779LeuGly: 1.779 ± 0.926
5.338LeuHis: 5.338 ± 2.778
5.338LeuIle: 5.338 ± 3.346
4.448LeuLys: 4.448 ± 1.479
4.448LeuLeu: 4.448 ± 1.458
0.89LeuMet: 0.89 ± 0.866
7.117LeuAsn: 7.117 ± 1.184
0.89LeuPro: 0.89 ± 0.979
4.448LeuGln: 4.448 ± 2.511
4.448LeuArg: 4.448 ± 2.712
6.228LeuSer: 6.228 ± 2.722
3.559LeuThr: 3.559 ± 1.325
3.559LeuVal: 3.559 ± 1.61
1.779LeuTrp: 1.779 ± 0.926
3.559LeuTyr: 3.559 ± 2.34
0.0LeuXaa: 0.0 ± 0.0
Met
1.779MetAla: 1.779 ± 1.066
0.0MetCys: 0.0 ± 0.0
2.669MetAsp: 2.669 ± 1.22
2.669MetGlu: 2.669 ± 1.497
3.559MetPhe: 3.559 ± 2.3
1.779MetGly: 1.779 ± 1.146
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
2.669MetLys: 2.669 ± 1.22
1.779MetLeu: 1.779 ± 1.422
0.0MetMet: 0.0 ± 0.0
1.779MetAsn: 1.779 ± 2.005
2.669MetPro: 2.669 ± 2.111
0.0MetGln: 0.0 ± 0.0
1.779MetArg: 1.779 ± 0.985
0.0MetSer: 0.0 ± 0.0
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
1.779MetTyr: 1.779 ± 1.527
0.0MetXaa: 0.0 ± 0.0
Asn
5.338AsnAla: 5.338 ± 2.829
0.89AsnCys: 0.89 ± 0.979
2.669AsnAsp: 2.669 ± 1.193
3.559AsnGlu: 3.559 ± 1.884
1.779AsnPhe: 1.779 ± 0.805
2.669AsnGly: 2.669 ± 1.183
6.228AsnHis: 6.228 ± 2.902
4.448AsnIle: 4.448 ± 0.935
2.669AsnLys: 2.669 ± 0.966
7.117AsnLeu: 7.117 ± 3.318
2.669AsnMet: 2.669 ± 1.371
2.669AsnAsn: 2.669 ± 1.787
4.448AsnPro: 4.448 ± 1.153
1.779AsnGln: 1.779 ± 1.406
2.669AsnArg: 2.669 ± 1.193
6.228AsnSer: 6.228 ± 3.626
2.669AsnThr: 2.669 ± 1.193
5.338AsnVal: 5.338 ± 1.346
0.0AsnTrp: 0.0 ± 0.0
1.779AsnTyr: 1.779 ± 0.926
0.0AsnXaa: 0.0 ± 0.0
Pro
2.669ProAla: 2.669 ± 1.811
1.779ProCys: 1.779 ± 0.985
0.89ProAsp: 0.89 ± 0.596
0.89ProGlu: 0.89 ± 0.596
2.669ProPhe: 2.669 ± 1.183
1.779ProGly: 1.779 ± 0.883
2.669ProHis: 2.669 ± 1.787
5.338ProIle: 5.338 ± 2.067
2.669ProLys: 2.669 ± 1.209
3.559ProLeu: 3.559 ± 1.258
3.559ProMet: 3.559 ± 1.188
5.338ProAsn: 5.338 ± 2.146
2.669ProPro: 2.669 ± 1.859
4.448ProGln: 4.448 ± 2.887
5.338ProArg: 5.338 ± 1.448
6.228ProSer: 6.228 ± 2.796
6.228ProThr: 6.228 ± 2.914
0.89ProVal: 0.89 ± 0.763
0.0ProTrp: 0.0 ± 0.0
2.669ProTyr: 2.669 ± 2.29
0.0ProXaa: 0.0 ± 0.0
Gln
3.559GlnAla: 3.559 ± 2.007
0.0GlnCys: 0.0 ± 0.0
2.669GlnAsp: 2.669 ± 1.176
3.559GlnGlu: 3.559 ± 2.662
2.669GlnPhe: 2.669 ± 1.787
1.779GlnGly: 1.779 ± 1.146
0.89GlnHis: 0.89 ± 0.979
5.338GlnIle: 5.338 ± 1.955
0.0GlnLys: 0.0 ± 0.0
1.779GlnLeu: 1.779 ± 0.973
0.0GlnMet: 0.0 ± 0.0
1.779GlnAsn: 1.779 ± 0.805
6.228GlnPro: 6.228 ± 4.21
0.0GlnGln: 0.0 ± 0.0
3.559GlnArg: 3.559 ± 1.037
3.559GlnSer: 3.559 ± 1.102
2.669GlnThr: 2.669 ± 2.237
2.669GlnVal: 2.669 ± 1.466
0.89GlnTrp: 0.89 ± 0.763
1.779GlnTyr: 1.779 ± 0.883
0.0GlnXaa: 0.0 ± 0.0
Arg
1.779ArgAla: 1.779 ± 1.17
2.669ArgCys: 2.669 ± 0.818
4.448ArgAsp: 4.448 ± 1.9
3.559ArgGlu: 3.559 ± 1.588
1.779ArgPhe: 1.779 ± 0.926
3.559ArgGly: 3.559 ± 1.248
0.89ArgHis: 0.89 ± 1.046
4.448ArgIle: 4.448 ± 1.618
3.559ArgLys: 3.559 ± 1.652
1.779ArgLeu: 1.779 ± 1.527
2.669ArgMet: 2.669 ± 1.563
3.559ArgAsn: 3.559 ± 1.946
7.117ArgPro: 7.117 ± 2.436
0.89ArgGln: 0.89 ± 0.898
6.228ArgArg: 6.228 ± 2.892
10.676ArgSer: 10.676 ± 2.162
2.669ArgThr: 2.669 ± 0.966
1.779ArgVal: 1.779 ± 1.406
0.0ArgTrp: 0.0 ± 0.0
0.89ArgTyr: 0.89 ± 0.763
0.0ArgXaa: 0.0 ± 0.0
Ser
4.448SerAla: 4.448 ± 2.054
0.0SerCys: 0.0 ± 0.0
5.338SerAsp: 5.338 ± 1.651
0.89SerGlu: 0.89 ± 0.596
3.559SerPhe: 3.559 ± 1.614
4.448SerGly: 4.448 ± 0.852
1.779SerHis: 1.779 ± 1.452
4.448SerIle: 4.448 ± 3.084
2.669SerLys: 2.669 ± 1.056
6.228SerLeu: 6.228 ± 1.665
0.89SerMet: 0.89 ± 1.046
5.338SerAsn: 5.338 ± 1.448
10.676SerPro: 10.676 ± 2.07
2.669SerGln: 2.669 ± 1.282
5.338SerArg: 5.338 ± 2.711
11.566SerSer: 11.566 ± 3.657
5.338SerThr: 5.338 ± 2.01
3.559SerVal: 3.559 ± 1.971
0.0SerTrp: 0.0 ± 0.0
2.669SerTyr: 2.669 ± 1.209
0.0SerXaa: 0.0 ± 0.0
Thr
2.669ThrAla: 2.669 ± 1.331
2.669ThrCys: 2.669 ± 1.994
1.779ThrAsp: 1.779 ± 1.275
5.338ThrGlu: 5.338 ± 1.624
0.0ThrPhe: 0.0 ± 0.0
6.228ThrGly: 6.228 ± 2.311
5.338ThrHis: 5.338 ± 2.554
3.559ThrIle: 3.559 ± 1.853
2.669ThrLys: 2.669 ± 1.209
2.669ThrLeu: 2.669 ± 1.192
0.89ThrMet: 0.89 ± 1.002
3.559ThrAsn: 3.559 ± 1.474
4.448ThrPro: 4.448 ± 2.801
2.669ThrGln: 2.669 ± 1.192
0.89ThrArg: 0.89 ± 0.763
3.559ThrSer: 3.559 ± 1.942
2.669ThrThr: 2.669 ± 2.333
5.338ThrVal: 5.338 ± 1.678
0.89ThrTrp: 0.89 ± 1.046
2.669ThrTyr: 2.669 ± 0.906
0.0ThrXaa: 0.0 ± 0.0
Val
0.89ValAla: 0.89 ± 1.046
0.89ValCys: 0.89 ± 0.596
1.779ValAsp: 1.779 ± 0.926
0.0ValGlu: 0.0 ± 0.0
4.448ValPhe: 4.448 ± 1.056
0.89ValGly: 0.89 ± 0.898
3.559ValHis: 3.559 ± 2.023
1.779ValIle: 1.779 ± 2.005
3.559ValLys: 3.559 ± 1.423
7.117ValLeu: 7.117 ± 1.902
0.0ValMet: 0.0 ± 0.0
2.669ValAsn: 2.669 ± 1.193
1.779ValPro: 1.779 ± 0.805
1.779ValGln: 1.779 ± 1.275
3.559ValArg: 3.559 ± 3.053
2.669ValSer: 2.669 ± 1.365
5.338ValThr: 5.338 ± 3.805
0.89ValVal: 0.89 ± 0.763
0.0ValTrp: 0.0 ± 0.0
1.779ValTyr: 1.779 ± 0.985
0.0ValXaa: 0.0 ± 0.0
Trp
2.669TrpAla: 2.669 ± 1.787
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
1.779TrpPhe: 1.779 ± 0.973
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.89TrpLys: 0.89 ± 1.046
0.89TrpLeu: 0.89 ± 0.763
0.89TrpMet: 0.89 ± 0.763
1.779TrpAsn: 1.779 ± 2.005
0.0TrpPro: 0.0 ± 0.0
1.779TrpGln: 1.779 ± 0.805
0.89TrpArg: 0.89 ± 0.979
0.0TrpSer: 0.0 ± 0.0
0.89TrpThr: 0.89 ± 1.002
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.669TyrAla: 2.669 ± 1.451
0.89TyrCys: 0.89 ± 0.979
1.779TyrAsp: 1.779 ± 1.17
0.89TyrGlu: 0.89 ± 0.763
1.779TyrPhe: 1.779 ± 1.17
1.779TyrGly: 1.779 ± 0.805
1.779TyrHis: 1.779 ± 1.066
3.559TyrIle: 3.559 ± 1.796
0.89TyrLys: 0.89 ± 0.596
5.338TyrLeu: 5.338 ± 2.219
2.669TyrMet: 2.669 ± 0.964
0.89TyrAsn: 0.89 ± 0.763
0.89TyrPro: 0.89 ± 0.596
1.779TyrGln: 1.779 ± 0.985
1.779TyrArg: 1.779 ± 1.527
1.779TyrSer: 1.779 ± 0.883
1.779TyrThr: 1.779 ± 1.422
0.89TyrVal: 0.89 ± 0.763
0.89TyrTrp: 0.89 ± 0.596
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1125 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski