Beihai barnacle viurs 1
Average proteome isoelectric point is 6.79
Get precalculated fractions of proteins
Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
All
Note: above files contain also dissociation constants (pKa)
Virtual 2D-PAGE plot for 1 proteins (isoelectric point calculated using IPC2_protein)
Get csv file with sequences according to given criteria:
* You can choose from 21 different methods for calculating isoelectric point
Summary statistics related to proteome-wise predictions
Protein with the lowest isoelectric point:
>tr|A0A0P0QKJ0|A0A0P0QKJ0_9VIRU Polyprotein OS=Beihai barnacle viurs 1 OX=1746057 PE=4 SV=1
MM1 pKa = 7.16 TKK3 pKa = 8.83 KK4 pKa = 8.44 TVQRR8 pKa = 11.84 RR9 pKa = 11.84 VVSDD13 pKa = 3.48 SLFEE17 pKa = 4.08 FVLPARR23 pKa = 11.84 VRR25 pKa = 11.84 DD26 pKa = 3.88 TGSVKK31 pKa = 10.81 AKK33 pKa = 10.04 VSCDD37 pKa = 3.42 LPYY40 pKa = 10.27 VTLDD44 pKa = 3.55 DD45 pKa = 3.95 EE46 pKa = 4.74 RR47 pKa = 11.84 VLAEE51 pKa = 3.92 EE52 pKa = 4.54 HH53 pKa = 7.06 DD54 pKa = 4.4 EE55 pKa = 4.18 KK56 pKa = 10.64 TSRR59 pKa = 11.84 QRR61 pKa = 11.84 DD62 pKa = 3.51 EE63 pKa = 3.78 ASKK66 pKa = 10.37 RR67 pKa = 11.84 RR68 pKa = 11.84 SGRR71 pKa = 11.84 EE72 pKa = 3.8 FRR74 pKa = 11.84 WGAAVAKK81 pKa = 10.27 RR82 pKa = 11.84 RR83 pKa = 11.84 LEE85 pKa = 3.95 EE86 pKa = 3.82 EE87 pKa = 4.11 AYY89 pKa = 10.07 EE90 pKa = 4.56 LYY92 pKa = 10.82 DD93 pKa = 5.49 LEE95 pKa = 4.52 TEE97 pKa = 3.93 ADD99 pKa = 3.42 KK100 pKa = 11.4 ARR102 pKa = 11.84 SRR104 pKa = 11.84 RR105 pKa = 11.84 YY106 pKa = 8.66 QQLVYY111 pKa = 10.57 DD112 pKa = 4.23 RR113 pKa = 11.84 SFAARR118 pKa = 11.84 CGEE121 pKa = 4.15 LDD123 pKa = 3.42 ALLAIEE129 pKa = 4.94 VKK131 pKa = 10.46 RR132 pKa = 11.84 QALVDD137 pKa = 3.54 QAIADD142 pKa = 4.32 LEE144 pKa = 4.29 QVGAYY149 pKa = 9.31 RR150 pKa = 11.84 RR151 pKa = 11.84 AEE153 pKa = 3.84 AAKK156 pKa = 10.28 LRR158 pKa = 11.84 EE159 pKa = 3.96 DD160 pKa = 3.67 AYY162 pKa = 10.33 FAEE165 pKa = 5.0 RR166 pKa = 11.84 LGEE169 pKa = 4.08 LDD171 pKa = 4.66 ALISQLGAEE180 pKa = 4.75 LSYY183 pKa = 11.51 AQGQYY188 pKa = 11.01 DD189 pKa = 4.72 AIYY192 pKa = 9.7 CSEE195 pKa = 4.05 EE196 pKa = 3.87 AVEE199 pKa = 4.59 IDD201 pKa = 4.03 CDD203 pKa = 3.78 TKK205 pKa = 10.86 RR206 pKa = 11.84 GEE208 pKa = 4.09 FLAASTEE215 pKa = 4.02 YY216 pKa = 11.11 DD217 pKa = 2.83 EE218 pKa = 4.6 TMRR221 pKa = 11.84 LKK223 pKa = 10.97 KK224 pKa = 9.48 EE225 pKa = 4.03 VNRR228 pKa = 11.84 IRR230 pKa = 11.84 HH231 pKa = 4.83 AQRR234 pKa = 11.84 KK235 pKa = 7.48 RR236 pKa = 11.84 GYY238 pKa = 10.46 YY239 pKa = 9.76 GVNDD243 pKa = 4.34 EE244 pKa = 4.86 GWLIACGSGRR254 pKa = 11.84 SKK256 pKa = 11.19 DD257 pKa = 3.77 DD258 pKa = 3.41 CEE260 pKa = 4.82 KK261 pKa = 11.05 CIEE264 pKa = 4.12 THH266 pKa = 6.1 NAFEE270 pKa = 4.21 VLEE273 pKa = 4.2 CQPLPEE279 pKa = 5.25 RR280 pKa = 11.84 DD281 pKa = 3.36 SDD283 pKa = 4.7 GEE285 pKa = 4.25 VPKK288 pKa = 11.07 NGEE291 pKa = 3.88 QKK293 pKa = 10.57 RR294 pKa = 11.84 LRR296 pKa = 11.84 KK297 pKa = 9.47 VVRR300 pKa = 11.84 KK301 pKa = 8.94 PKK303 pKa = 10.24 RR304 pKa = 11.84 ADD306 pKa = 3.36 NFDD309 pKa = 3.62 EE310 pKa = 5.09 LMAEE314 pKa = 3.96 AAKK317 pKa = 10.1 WNAEE321 pKa = 4.08 CEE323 pKa = 4.39 KK324 pKa = 10.79 QGATLMPSRR333 pKa = 11.84 AAYY336 pKa = 8.97 EE337 pKa = 4.15 AIARR341 pKa = 11.84 KK342 pKa = 9.18 RR343 pKa = 11.84 VRR345 pKa = 11.84 SFGVRR350 pKa = 11.84 GEE352 pKa = 4.21 EE353 pKa = 4.03 KK354 pKa = 10.59 QEE356 pKa = 3.94 LLLIASNTVEE366 pKa = 4.12 VVEE369 pKa = 5.2 RR370 pKa = 11.84 LTKK373 pKa = 10.91 ANGSSGKK380 pKa = 7.16 EE381 pKa = 3.77 TKK383 pKa = 9.67 EE384 pKa = 3.77 EE385 pKa = 3.83 KK386 pKa = 9.87 FRR388 pKa = 11.84 RR389 pKa = 11.84 AFGKK393 pKa = 10.09 QGEE396 pKa = 4.29 ILYY399 pKa = 10.52 EE400 pKa = 3.96 SGKK403 pKa = 9.9 WYY405 pKa = 10.46 LRR407 pKa = 11.84 RR408 pKa = 11.84 CNHH411 pKa = 5.65 TFGTSVQNGDD421 pKa = 3.67 IQWFALTLRR430 pKa = 11.84 KK431 pKa = 9.76 GVAIKK436 pKa = 9.89 TEE438 pKa = 3.97 AKK440 pKa = 9.93 APRR443 pKa = 11.84 FGSYY447 pKa = 9.91 YY448 pKa = 9.99 EE449 pKa = 4.42 HH450 pKa = 7.26 GAMMWYY456 pKa = 8.65 QNKK459 pKa = 9.07 VEE461 pKa = 4.11 RR462 pKa = 11.84 CGLVEE467 pKa = 4.18 VSCLEE472 pKa = 3.82 ASRR475 pKa = 11.84 LKK477 pKa = 10.89 GKK479 pKa = 10.46 SGTNCFGGTLLGVIHH494 pKa = 7.55 DD495 pKa = 4.35 IDD497 pKa = 3.91 YY498 pKa = 10.36 DD499 pKa = 4.1 YY500 pKa = 11.48 YY501 pKa = 11.23 GAVIHH506 pKa = 6.41 TSDD509 pKa = 3.69 PVEE512 pKa = 4.41 EE513 pKa = 4.15 IQYY516 pKa = 10.62 HH517 pKa = 5.59 VDD519 pKa = 3.5 HH520 pKa = 7.15 HH521 pKa = 7.33 DD522 pKa = 3.44 DD523 pKa = 3.15 WVDD526 pKa = 2.87 IGRR529 pKa = 11.84 SFGEE533 pKa = 3.94 EE534 pKa = 3.74 RR535 pKa = 11.84 GKK537 pKa = 8.12 MTYY540 pKa = 9.07 TPCSKK545 pKa = 9.5 TALTFMCLLSSVFSCEE561 pKa = 4.11 VVSEE565 pKa = 4.17 IYY567 pKa = 9.07 GTYY570 pKa = 10.15 LVNEE574 pKa = 4.47 IQQLDD579 pKa = 3.77 WPSGEE584 pKa = 4.39 TEE586 pKa = 4.85 CMIPPCIGCSDD597 pKa = 4.37 LEE599 pKa = 4.56 CGVGYY604 pKa = 10.61 DD605 pKa = 3.73 LATWQYY611 pKa = 10.58 ICNQADD617 pKa = 3.57 LCIEE621 pKa = 4.09 SEE623 pKa = 4.28 ALVMLFNSNYY633 pKa = 10.37 SVDD636 pKa = 4.54 LDD638 pKa = 4.02 CMYY641 pKa = 8.56 NTPRR645 pKa = 11.84 QRR647 pKa = 11.84 TKK649 pKa = 10.84 RR650 pKa = 11.84 DD651 pKa = 3.27 TSSSDD656 pKa = 3.1 EE657 pKa = 4.39 TFSSLVNKK665 pKa = 10.46 FGFDD669 pKa = 3.03 ASAIKK674 pKa = 10.36 EE675 pKa = 4.15 KK676 pKa = 10.25 ATSFKK681 pKa = 11.09 DD682 pKa = 3.25 KK683 pKa = 10.61 VVEE686 pKa = 3.84 YY687 pKa = 10.08 SRR689 pKa = 11.84 NSIVIAVTILLFWLSLTLLGVSPVVSMIFIVLSFYY724 pKa = 10.55 ISSVQSVNIAKK735 pKa = 10.32 DD736 pKa = 3.32 RR737 pKa = 11.84 TNCRR741 pKa = 11.84 IEE743 pKa = 3.91 YY744 pKa = 9.19 RR745 pKa = 11.84 KK746 pKa = 9.65 PDD748 pKa = 3.27 LTVRR752 pKa = 11.84 SGCATNTRR760 pKa = 11.84 MFSGVIFCNQTGVSGCGWYY779 pKa = 8.14 ITFGNFKK786 pKa = 10.49 SDD788 pKa = 2.75 MRR790 pKa = 11.84 TRR792 pKa = 11.84 ALSCVSDD799 pKa = 3.82 DD800 pKa = 4.88 QMKK803 pKa = 9.94 FWIEE807 pKa = 3.58 QTPTQKK813 pKa = 10.15 FVRR816 pKa = 11.84 SYY818 pKa = 10.97 CAANPLDD825 pKa = 3.71 IVGLTRR831 pKa = 11.84 KK832 pKa = 9.16 VVEE835 pKa = 4.29 YY836 pKa = 10.74 YY837 pKa = 10.5 FGYY840 pKa = 10.02 LQEE843 pKa = 4.44 PSEE846 pKa = 4.13 AHH848 pKa = 6.48 LKK850 pKa = 10.39 RR851 pKa = 11.84 ISDD854 pKa = 3.64 EE855 pKa = 4.28 FSRR858 pKa = 11.84 TMTHH862 pKa = 7.55 LLGTKK867 pKa = 9.95 YY868 pKa = 10.79 YY869 pKa = 9.81 EE870 pKa = 3.9 ILYY873 pKa = 8.52 KK874 pKa = 10.26 ICVGVICLVALLILPFPLGAIVAIMFVSVYY904 pKa = 9.48 IAEE907 pKa = 4.43 AASVCQTSMVMTQSGLQYY925 pKa = 10.55 HH926 pKa = 6.06 VGGLEE931 pKa = 3.91 KK932 pKa = 10.01 TVTRR936 pKa = 11.84 GKK938 pKa = 10.45 VKK940 pKa = 10.38 VSRR943 pKa = 11.84 GFCLRR948 pKa = 11.84 WHH950 pKa = 6.36 EE951 pKa = 4.33 KK952 pKa = 8.26 EE953 pKa = 4.29 TVVVDD958 pKa = 3.75 NVQSEE963 pKa = 4.72 VFTQHH968 pKa = 7.07 KK969 pKa = 10.13 IDD971 pKa = 5.24 VLDD974 pKa = 3.5 QTPNFHH980 pKa = 5.95 TTDD983 pKa = 2.66 IVRR986 pKa = 11.84 IVATPKK992 pKa = 9.57 IDD994 pKa = 3.46 HH995 pKa = 6.49 LCSYY999 pKa = 9.76 RR1000 pKa = 11.84 CKK1002 pKa = 10.62 KK1003 pKa = 10.22 SWLDD1007 pKa = 3.19 TFEE1010 pKa = 5.25 RR1011 pKa = 11.84 EE1012 pKa = 3.69 EE1013 pKa = 3.97 RR1014 pKa = 11.84 LISGGAYY1021 pKa = 9.76 VYY1023 pKa = 10.78 KK1024 pKa = 10.3 CNRR1027 pKa = 11.84 WTRR1030 pKa = 11.84 EE1031 pKa = 3.38 RR1032 pKa = 11.84 KK1033 pKa = 10.08 LYY1035 pKa = 9.54 WGSSWDD1041 pKa = 3.28 ASYY1044 pKa = 11.05 EE1045 pKa = 4.14 HH1046 pKa = 7.01 YY1047 pKa = 10.97 DD1048 pKa = 2.81 GWTCNGCPGASYY1060 pKa = 10.86 SFKK1063 pKa = 10.58 KK1064 pKa = 10.2 SCIYY1068 pKa = 9.54 WKK1070 pKa = 10.73 RR1071 pKa = 11.84 EE1072 pKa = 3.99 DD1073 pKa = 3.35 EE1074 pKa = 4.94 CVFQNKK1080 pKa = 8.69 IVEE1083 pKa = 4.35 SLTMKK1088 pKa = 9.97 VRR1090 pKa = 11.84 YY1091 pKa = 7.06 TKK1093 pKa = 11.12 NEE1095 pKa = 3.81 VEE1097 pKa = 4.26 EE1098 pKa = 4.71 DD1099 pKa = 3.41 RR1100 pKa = 11.84 VFTVTRR1106 pKa = 11.84 DD1107 pKa = 3.33 SPFTLGGVTFHH1118 pKa = 6.94 LLSHH1122 pKa = 6.1 KK1123 pKa = 9.93 HH1124 pKa = 5.35 IKK1126 pKa = 10.18 YY1127 pKa = 10.52 DD1128 pKa = 4.43 VINCQDD1134 pKa = 2.98 RR1135 pKa = 11.84 KK1136 pKa = 10.77 YY1137 pKa = 10.98 LVNDD1141 pKa = 4.43 RR1142 pKa = 11.84 SAIPQDD1148 pKa = 3.41 VIQYY1152 pKa = 9.13 NEE1154 pKa = 3.81 KK1155 pKa = 10.66 SEE1157 pKa = 3.82 ITEE1160 pKa = 3.83 RR1161 pKa = 11.84 YY1162 pKa = 9.36 LFSRR1166 pKa = 11.84 CSTHH1170 pKa = 6.03 YY1171 pKa = 10.27 VCKK1174 pKa = 10.02 TYY1176 pKa = 11.27 SNSCNDD1182 pKa = 3.33 KK1183 pKa = 11.13 NGAICTWKK1191 pKa = 10.6 SLTHH1195 pKa = 6.49 AMPPRR1200 pKa = 11.84 SLSEE1204 pKa = 3.94 TTMLIHH1210 pKa = 7.26 PEE1212 pKa = 3.9 AKK1214 pKa = 8.71 QTWGHH1219 pKa = 6.19 FEE1221 pKa = 4.43 LLVSGQVTEE1230 pKa = 4.2 TTICKK1235 pKa = 8.4 TFRR1238 pKa = 11.84 VHH1240 pKa = 4.92 PTGRR1244 pKa = 11.84 VDD1246 pKa = 4.22 FTTSSSGFVEE1256 pKa = 5.08 FTFDD1260 pKa = 3.48 AHH1262 pKa = 7.04 KK1263 pKa = 10.56 LPCIPEE1269 pKa = 4.14 LNAIDD1274 pKa = 4.46 SDD1276 pKa = 3.93 EE1277 pKa = 4.9 CEE1279 pKa = 4.25 VTILRR1284 pKa = 11.84 PTLTDD1289 pKa = 3.02 NATEE1293 pKa = 3.78 VSMGVTCRR1301 pKa = 11.84 RR1302 pKa = 11.84 VQVANFSVDD1311 pKa = 3.11 GQQVVATVRR1320 pKa = 11.84 YY1321 pKa = 9.94 VKK1323 pKa = 10.42 FANYY1327 pKa = 10.36 DD1328 pKa = 3.75 LLEE1331 pKa = 4.31 NAAIEE1336 pKa = 4.57 FWSSGGEE1343 pKa = 3.37 IGSFGEE1349 pKa = 5.12 AISDD1353 pKa = 3.46 WFHH1356 pKa = 5.29 QTFSFKK1362 pKa = 9.92 WPNLRR1367 pKa = 11.84 EE1368 pKa = 3.97 IGVKK1372 pKa = 10.0 VLIVLVIYY1380 pKa = 8.37 MVSPPLAIFVVIFYY1394 pKa = 9.1 FLINGAFAVEE1404 pKa = 4.62 GNCYY1408 pKa = 10.39 GYY1410 pKa = 10.68 VANSNGRR1417 pKa = 11.84 TIMNKK1422 pKa = 7.74 WLYY1425 pKa = 10.46 EE1426 pKa = 3.8 KK1427 pKa = 10.49 GISYY1431 pKa = 7.65 NTHH1434 pKa = 5.25 GFFFGGIPDD1443 pKa = 3.92 SACDD1447 pKa = 3.48 SRR1449 pKa = 11.84 RR1450 pKa = 11.84 GQIVKK1455 pKa = 9.28 EE1456 pKa = 3.98 KK1457 pKa = 10.09 CDD1459 pKa = 3.43 QILYY1463 pKa = 10.22 RR1464 pKa = 11.84 LEE1466 pKa = 3.93 SLKK1469 pKa = 10.24 WYY1471 pKa = 10.61 SNSPVNDD1478 pKa = 3.57 RR1479 pKa = 11.84 LNDD1482 pKa = 3.25 VTCRR1486 pKa = 11.84 HH1487 pKa = 6.77 EE1488 pKa = 4.21 YY1489 pKa = 9.76 CKK1491 pKa = 10.6 HH1492 pKa = 6.3 GIGADD1497 pKa = 3.64 LSFEE1501 pKa = 4.32 EE1502 pKa = 4.51 YY1503 pKa = 10.73 VDD1505 pKa = 6.13 LIEE1508 pKa = 5.72 DD1509 pKa = 3.88 CAKK1512 pKa = 10.39 TSVTKK1517 pKa = 9.92 IWYY1520 pKa = 8.77 PRR1522 pKa = 11.84 EE1523 pKa = 3.8 CTKK1526 pKa = 11.11 NVINEE1531 pKa = 3.87 VTTNKK1536 pKa = 9.95 SANINCPVNGLVLNGKK1552 pKa = 7.64 EE1553 pKa = 4.19 VIVPFSVAGGEE1564 pKa = 4.1 RR1565 pKa = 11.84 EE1566 pKa = 4.2 TVSFYY1571 pKa = 10.59 IKK1573 pKa = 10.52 LVIVYY1578 pKa = 8.76 VVLSVLFVNLEE1589 pKa = 3.9 MPDD1592 pKa = 3.69 INNLAALCHH1601 pKa = 5.98 NPAFEE1606 pKa = 4.52 LLVDD1610 pKa = 3.65 ITCIVLNPLNLMVLLLVKK1628 pKa = 10.31 RR1629 pKa = 11.84 LHH1631 pKa = 7.33 LSFCCSCLVIIFASVVEE1648 pKa = 4.19 NTLIALVTAFVRR1660 pKa = 11.84 IAAMVYY1666 pKa = 9.6 SKK1668 pKa = 10.62 SIHH1671 pKa = 5.92 FPFVASNIEE1680 pKa = 3.98 YY1681 pKa = 5.87 WTKK1684 pKa = 10.53 YY1685 pKa = 10.23 DD1686 pKa = 4.32 DD1687 pKa = 4.02 RR1688 pKa = 11.84 GSLFTSPASKK1698 pKa = 10.19 VVKK1701 pKa = 9.99 SICDD1705 pKa = 3.33 SGCQTEE1711 pKa = 4.42 GNMVVQSCDD1720 pKa = 2.98 IVLEE1724 pKa = 4.4 RR1725 pKa = 11.84 YY1726 pKa = 9.37 NGVWIRR1732 pKa = 11.84 KK1733 pKa = 7.06 EE1734 pKa = 3.7 LHH1736 pKa = 6.39 SEE1738 pKa = 4.21 DD1739 pKa = 3.95 IEE1741 pKa = 4.09 PLARR1745 pKa = 11.84 EE1746 pKa = 4.44 DD1747 pKa = 5.09 CPVDD1751 pKa = 3.61 PYY1753 pKa = 11.26 KK1754 pKa = 10.73 YY1755 pKa = 9.32 EE1756 pKa = 4.23 CGIKK1760 pKa = 9.99 ISVSKK1765 pKa = 10.03 TSDD1768 pKa = 3.71 DD1769 pKa = 3.4 VDD1771 pKa = 3.75 GDD1773 pKa = 4.42 SNEE1776 pKa = 3.47 HH1777 pKa = 5.97 RR1778 pKa = 11.84 NYY1780 pKa = 9.64 IRR1782 pKa = 11.84 SVVDD1786 pKa = 3.76 FEE1788 pKa = 5.49 SNSRR1792 pKa = 11.84 PDD1794 pKa = 3.63 LNKK1797 pKa = 9.28 ATPKK1801 pKa = 9.08 VTEE1804 pKa = 4.17 AAQLCINPHH1813 pKa = 4.91 VKK1815 pKa = 10.43 CMLDD1819 pKa = 3.16 MFEE1822 pKa = 5.07 PFINNNTVGHH1832 pKa = 6.98 LALEE1836 pKa = 4.24 YY1837 pKa = 10.38 SNCEE1841 pKa = 4.08 IIQSWFGRR1849 pKa = 11.84 LEE1851 pKa = 4.4 SIVGKK1856 pKa = 9.14 EE1857 pKa = 3.89 WEE1859 pKa = 4.32 SQVAIMQLTTFSKK1872 pKa = 10.6 RR1873 pKa = 11.84 GFCFAYY1879 pKa = 10.24 GGGIYY1884 pKa = 9.34 TAMHH1888 pKa = 5.6 VTHH1891 pKa = 7.21 GDD1893 pKa = 3.85 SIFHH1897 pKa = 6.96 PGYY1900 pKa = 10.48 KK1901 pKa = 9.89 PLPCTFNSEE1910 pKa = 4.14 EE1911 pKa = 4.31 EE1912 pKa = 4.55 DD1913 pKa = 3.19 ICVYY1917 pKa = 10.92 GDD1919 pKa = 3.8 PLEE1922 pKa = 5.0 LEE1924 pKa = 4.14 QPKK1927 pKa = 9.88 TGDD1930 pKa = 2.85 LYY1932 pKa = 11.61 YY1933 pKa = 10.97 VVNPKK1938 pKa = 10.5 LGVYY1942 pKa = 9.49 VVLSLQKK1949 pKa = 9.78 EE1950 pKa = 4.08 QWGNKK1955 pKa = 5.85 YY1956 pKa = 9.27 YY1957 pKa = 10.75 RR1958 pKa = 11.84 RR1959 pKa = 11.84 IVSGDD1964 pKa = 3.45 YY1965 pKa = 10.64 KK1966 pKa = 10.87 VINYY1970 pKa = 9.52 ADD1972 pKa = 3.32 QRR1974 pKa = 11.84 GTLFRR1979 pKa = 11.84 NDD1981 pKa = 3.9 FDD1983 pKa = 6.0 DD1984 pKa = 5.17 EE1985 pKa = 4.49 PATQSLFSSDD1995 pKa = 3.26 SCNLHH2000 pKa = 5.93 GWSGLPICRR2009 pKa = 11.84 ISDD2012 pKa = 3.88 GKK2014 pKa = 10.0 PVGIYY2019 pKa = 9.86 TGTEE2023 pKa = 4.08 KK2024 pKa = 10.02 IDD2026 pKa = 3.3 GSIWIKK2032 pKa = 10.64 NVSPTKK2038 pKa = 10.46 IPAQPFNRR2046 pKa = 11.84 IINDD2050 pKa = 3.26 ILDD2053 pKa = 3.94 TPTVRR2058 pKa = 11.84 FTLDD2062 pKa = 2.91 APTGAGKK2069 pKa = 6.87 TTRR2072 pKa = 11.84 FVLQLAEE2079 pKa = 4.39 QSILKK2084 pKa = 9.65 NKK2086 pKa = 9.31 PIHH2089 pKa = 6.44 ILVANPLLTITYY2101 pKa = 8.46 AYY2103 pKa = 10.05 EE2104 pKa = 4.31 FVKK2107 pKa = 9.39 HH2108 pKa = 5.46 TLLEE2112 pKa = 4.35 KK2113 pKa = 10.76 SSLRR2117 pKa = 11.84 DD2118 pKa = 3.67 KK2119 pKa = 11.11 ISMNLQTSSVTKK2131 pKa = 11.12 YY2132 pKa = 7.05 EE2133 pKa = 4.25 TKK2135 pKa = 10.37 KK2136 pKa = 10.48 LASITYY2142 pKa = 6.51 MTYY2145 pKa = 10.87 GCVLNQMKK2153 pKa = 10.65 NNASLPYY2160 pKa = 10.26 DD2161 pKa = 3.02 IVLLDD2166 pKa = 4.1 EE2167 pKa = 4.58 CHH2169 pKa = 6.47 TDD2171 pKa = 3.35 QPHH2174 pKa = 4.73 VVAVLTAKK2182 pKa = 10.38 NLPRR2186 pKa = 11.84 HH2187 pKa = 5.54 VLMTATPLFGGLAPSYY2203 pKa = 10.22 RR2204 pKa = 11.84 SNIDD2208 pKa = 2.94 VRR2210 pKa = 11.84 KK2211 pKa = 8.38 ITHH2214 pKa = 6.94 KK2215 pKa = 10.09 STAAQGFVEE2224 pKa = 5.89 LYY2226 pKa = 9.46 TNTFVKK2232 pKa = 10.69 QEE2234 pKa = 3.97 VFEE2237 pKa = 4.84 DD2238 pKa = 3.65 LCKK2241 pKa = 10.13 PGSIIFCGSIAEE2253 pKa = 4.11 TDD2255 pKa = 3.35 KK2256 pKa = 11.37 VKK2258 pKa = 10.96 NRR2260 pKa = 11.84 IQKK2263 pKa = 9.67 QNAEE2267 pKa = 4.15 AQVVTVSSKK2276 pKa = 9.14 TPLRR2280 pKa = 11.84 EE2281 pKa = 3.82 VDD2283 pKa = 3.79 SSRR2286 pKa = 11.84 DD2287 pKa = 3.32 DD2288 pKa = 4.16 CVWVTTDD2295 pKa = 3.55 ALMSGVTIAKK2305 pKa = 9.29 AVRR2308 pKa = 11.84 GIAQGRR2314 pKa = 11.84 QFRR2317 pKa = 11.84 QTFSVVEE2324 pKa = 3.98 QRR2326 pKa = 11.84 AEE2328 pKa = 3.73 LMARR2332 pKa = 11.84 KK2333 pKa = 6.08 TTLSEE2338 pKa = 4.05 DD2339 pKa = 3.18 VQMAGRR2345 pKa = 11.84 IARR2348 pKa = 11.84 TPNSFGVWYY2357 pKa = 10.49 KK2358 pKa = 10.69 LDD2360 pKa = 3.76 EE2361 pKa = 4.71 YY2362 pKa = 10.7 YY2363 pKa = 10.6 HH2364 pKa = 6.1 EE2365 pKa = 5.35 PSWSPHH2371 pKa = 5.74 LLLSALTALNARR2383 pKa = 11.84 KK2384 pKa = 8.92 IQYY2387 pKa = 8.95 DD2388 pKa = 3.45 RR2389 pKa = 11.84 KK2390 pKa = 10.38 YY2391 pKa = 9.35 YY2392 pKa = 10.63 EE2393 pKa = 4.06 CVKK2396 pKa = 10.96 DD2397 pKa = 4.09 LVAGIADD2404 pKa = 4.61 DD2405 pKa = 5.02 DD2406 pKa = 4.4 EE2407 pKa = 5.48 LWVQADD2413 pKa = 3.8 KK2414 pKa = 11.74 NSIDD2418 pKa = 3.43 GVSFKK2423 pKa = 10.98 KK2424 pKa = 10.47 FLEE2427 pKa = 4.64 SGTIPYY2433 pKa = 10.19 HH2434 pKa = 6.87 FDD2436 pKa = 2.91 AKK2438 pKa = 10.99 LPGKK2442 pKa = 10.02 EE2443 pKa = 3.94 RR2444 pKa = 11.84 GTHH2447 pKa = 5.52 EE2448 pKa = 4.31 DD2449 pKa = 2.98 WFEE2452 pKa = 3.72 LSKK2455 pKa = 10.71 KK2456 pKa = 9.79 YY2457 pKa = 10.37 RR2458 pKa = 11.84 EE2459 pKa = 3.9 LSRR2462 pKa = 11.84 FDD2464 pKa = 4.06 EE2465 pKa = 4.62 NCAEE2469 pKa = 4.31 CGEE2472 pKa = 4.31 KK2473 pKa = 10.01 KK2474 pKa = 9.95 RR2475 pKa = 11.84 RR2476 pKa = 11.84 LRR2478 pKa = 11.84 RR2479 pKa = 11.84 DD2480 pKa = 3.34 HH2481 pKa = 7.02 EE2482 pKa = 4.12 EE2483 pKa = 3.92 HH2484 pKa = 6.79 AVGTIGLAVVAAGTTAGCLLAYY2506 pKa = 8.39 MCSHH2510 pKa = 5.58 QQVLVNDD2517 pKa = 3.75 VWWPQRR2523 pKa = 11.84 EE2524 pKa = 4.24 KK2525 pKa = 11.3 NFNGLLSGVTHH2536 pKa = 7.11 DD2537 pKa = 4.47 FVLGYY2542 pKa = 7.83 TEE2544 pKa = 5.43 KK2545 pKa = 10.75 EE2546 pKa = 3.89 LEE2548 pKa = 4.26 KK2549 pKa = 11.4 YY2550 pKa = 10.13 EE2551 pKa = 4.41 GFYY2554 pKa = 10.88 DD2555 pKa = 3.4 PHH2557 pKa = 7.73 YY2558 pKa = 10.66 KK2559 pKa = 9.5 ATFKK2563 pKa = 10.52 AWKK2566 pKa = 8.43 PDD2568 pKa = 3.16 RR2569 pKa = 11.84 SNDD2572 pKa = 3.24 EE2573 pKa = 3.56 GFIRR2577 pKa = 11.84 HH2578 pKa = 5.83 NLMIKK2583 pKa = 10.26 VPTSTNYY2590 pKa = 10.03 QMYY2593 pKa = 8.18 HH2594 pKa = 4.08 VKK2596 pKa = 10.18 YY2597 pKa = 9.54 RR2598 pKa = 11.84 NHH2600 pKa = 5.83 HH2601 pKa = 6.16 RR2602 pKa = 11.84 IARR2605 pKa = 11.84 NYY2607 pKa = 10.45 KK2608 pKa = 9.94 LDD2610 pKa = 3.64 EE2611 pKa = 4.77 HH2612 pKa = 7.38 PDD2614 pKa = 3.55 LDD2616 pKa = 3.83 WYY2618 pKa = 10.31 DD2619 pKa = 2.84 IRR2621 pKa = 11.84 NPVFSDD2627 pKa = 2.97 TDD2629 pKa = 3.07 GRR2631 pKa = 11.84 RR2632 pKa = 11.84 RR2633 pKa = 11.84 LMPDD2637 pKa = 2.94 EE2638 pKa = 5.41 LDD2640 pKa = 3.54 GFNPRR2645 pKa = 11.84 RR2646 pKa = 11.84 CVLEE2650 pKa = 3.3 QRR2652 pKa = 11.84 RR2653 pKa = 11.84 RR2654 pKa = 11.84 KK2655 pKa = 10.08 KK2656 pKa = 9.39 STLIKK2661 pKa = 10.84 GFIQQLIMLFGDD2673 pKa = 3.49 NTVTRR2678 pKa = 11.84 SIRR2681 pKa = 11.84 DD2682 pKa = 3.25 ALVPYY2687 pKa = 9.53 EE2688 pKa = 4.08 YY2689 pKa = 10.5 EE2690 pKa = 3.66 SDD2692 pKa = 3.03 RR2693 pKa = 11.84 MQRR2696 pKa = 11.84 HH2697 pKa = 6.77 AIFTYY2702 pKa = 9.91 VPFYY2706 pKa = 10.81 HH2707 pKa = 6.96 WFCIQTGTTPVLFMEE2722 pKa = 4.34 WLKK2725 pKa = 10.35 TYY2727 pKa = 10.65 GFAFLPAVMAPLGNEE2742 pKa = 3.47 IAGSVGSFILAIAATYY2758 pKa = 6.86 MTFYY2762 pKa = 10.54 TVGIKK2767 pKa = 10.04 ISYY2770 pKa = 9.78 DD2771 pKa = 3.17 VLAGVICANGFVTWLLNKK2789 pKa = 10.23 FGNASLKK2796 pKa = 10.79 KK2797 pKa = 10.19 NLLIDD2802 pKa = 3.84 TQAGLRR2808 pKa = 11.84 DD2809 pKa = 3.93 RR2810 pKa = 11.84 FTKK2813 pKa = 10.36 PFLISAVTMSAVVAYY2828 pKa = 10.12 QNGHH2832 pKa = 5.52 VGLPAVLTNLAEE2844 pKa = 4.27 EE2845 pKa = 4.0 ASKK2848 pKa = 10.77 RR2849 pKa = 11.84 IGLAPVTTTQSFVASVVEE2867 pKa = 3.95 GDD2869 pKa = 3.81 LVSFIYY2875 pKa = 10.41 RR2876 pKa = 11.84 CMRR2879 pKa = 11.84 FIDD2882 pKa = 3.85 EE2883 pKa = 5.03 GDD2885 pKa = 3.62 INSNWVAMCVDD2896 pKa = 3.7 VGITALNLPYY2906 pKa = 10.35 SQVAAAVVLAFLFYY2920 pKa = 10.72 LSKK2923 pKa = 11.03 KK2924 pKa = 9.84 NDD2926 pKa = 3.4 IIKK2929 pKa = 9.25 TVLIKK2934 pKa = 10.81 AQLLKK2939 pKa = 10.7 DD2940 pKa = 3.75 RR2941 pKa = 11.84 KK2942 pKa = 8.8 TSTEE2946 pKa = 3.75 DD2947 pKa = 2.84 AKK2949 pKa = 11.51 ASDD2952 pKa = 4.25 RR2953 pKa = 11.84 YY2954 pKa = 10.95 LLGEE2958 pKa = 5.31 DD2959 pKa = 3.21 IDD2961 pKa = 4.36 KK2962 pKa = 11.23 KK2963 pKa = 10.98 LVLDD2967 pKa = 4.25 AVCFLSYY2974 pKa = 10.45 CVNPLNMLKK2983 pKa = 10.6 AMSGFTVSYY2992 pKa = 9.89 IYY2994 pKa = 11.17 NKK2996 pKa = 6.82 VTRR2999 pKa = 11.84 RR3000 pKa = 11.84 DD3001 pKa = 3.57 FEE3003 pKa = 4.34 MKK3005 pKa = 10.65 DD3006 pKa = 3.5 LVLKK3010 pKa = 9.76 SLRR3013 pKa = 11.84 DD3014 pKa = 3.38 APMGVVYY3021 pKa = 9.19 MAKK3024 pKa = 9.73 QFYY3027 pKa = 10.18 CQITEE3032 pKa = 3.82 IANLILRR3039 pKa = 11.84 YY3040 pKa = 9.88 FGDD3043 pKa = 3.5 RR3044 pKa = 11.84 DD3045 pKa = 3.77 DD3046 pKa = 4.95 RR3047 pKa = 11.84 HH3048 pKa = 6.37 ASPDD3052 pKa = 3.46 NVLSGLYY3059 pKa = 9.5 EE3060 pKa = 4.04 LAVQKK3065 pKa = 10.89 CSGIPDD3071 pKa = 3.69 WFKK3074 pKa = 10.91 QSCSKK3079 pKa = 10.63 VKK3081 pKa = 10.53 QFICDD3086 pKa = 3.64 MVPGDD3091 pKa = 4.0 NVMLARR3097 pKa = 11.84 IRR3099 pKa = 11.84 IIFKK3103 pKa = 10.61 KK3104 pKa = 10.69 LFFKK3108 pKa = 10.67 PLLWVARR3115 pKa = 11.84 WFWSIAQKK3123 pKa = 10.89 IMGVCMLMSIPLIGASEE3140 pKa = 4.2 VLRR3143 pKa = 11.84 CILEE3147 pKa = 4.13 KK3148 pKa = 10.37 TFSFLGRR3155 pKa = 11.84 VNKK3158 pKa = 10.31 KK3159 pKa = 7.95 FTNLLYY3165 pKa = 10.75 GFTMSHH3171 pKa = 5.37 WEE3173 pKa = 3.85 YY3174 pKa = 10.48 NISIFASNEE3183 pKa = 3.77 QIRR3186 pKa = 11.84 TCMEE3190 pKa = 3.67 RR3191 pKa = 11.84 SKK3193 pKa = 10.29 MYY3195 pKa = 9.01 PHH3197 pKa = 7.16 WKK3199 pKa = 10.16 LEE3201 pKa = 3.87 RR3202 pKa = 11.84 LLAGLAEE3209 pKa = 4.62 PEE3211 pKa = 4.11 TEE3213 pKa = 4.04 RR3214 pKa = 11.84 RR3215 pKa = 11.84 RR3216 pKa = 11.84 SSTPNSSVDD3225 pKa = 3.22 EE3226 pKa = 3.93 QLNYY3230 pKa = 10.26 LEE3232 pKa = 4.77 RR3233 pKa = 11.84 MARR3236 pKa = 11.84 EE3237 pKa = 4.16 DD3238 pKa = 4.38 PEE3240 pKa = 4.2 VSMIGVNLEE3249 pKa = 4.16 CSGGGYY3255 pKa = 9.46 IDD3257 pKa = 4.89 DD3258 pKa = 5.79 SIRR3261 pKa = 11.84 QMSPEE3266 pKa = 3.79 RR3267 pKa = 11.84 LEE3269 pKa = 4.19 EE3270 pKa = 3.69 QDD3272 pKa = 3.16 RR3273 pKa = 11.84 QYY3275 pKa = 11.83 AEE3277 pKa = 4.34 AMGPNLGDD3285 pKa = 3.49 NCEE3288 pKa = 4.23 LEE3290 pKa = 4.42 ALSSEE3295 pKa = 4.25 RR3296 pKa = 11.84 VQHH3299 pKa = 5.92 CEE3301 pKa = 3.52 KK3302 pKa = 10.68 FSLLRR3307 pKa = 11.84 TLFDD3311 pKa = 3.77 MMIEE3315 pKa = 4.26 PPSEE3319 pKa = 4.17 DD3320 pKa = 3.18 MSPTANIYY3328 pKa = 9.15 VNKK3331 pKa = 9.59 PIEE3334 pKa = 3.83 WLQNVVEE3341 pKa = 4.43 VADD3344 pKa = 3.77 VDD3346 pKa = 3.88 QKK3348 pKa = 9.69 TKK3350 pKa = 10.66 RR3351 pKa = 11.84 EE3352 pKa = 4.14 SNIPYY3357 pKa = 9.63 YY3358 pKa = 10.31 SAYY3361 pKa = 10.2 LSGMNPHH3368 pKa = 6.73 PVDD3371 pKa = 3.68 PLEE3374 pKa = 4.23 EE3375 pKa = 4.17 KK3376 pKa = 8.74 TLKK3379 pKa = 8.23 MTEE3382 pKa = 3.89 DD3383 pKa = 4.25 TIWPDD3388 pKa = 3.27 LYY3390 pKa = 10.86 GAEE3393 pKa = 4.58 VIGNTQIAFEE3403 pKa = 4.15 KK3404 pKa = 10.42 LKK3406 pKa = 10.26 TILTVNVKK3414 pKa = 8.16 QKK3416 pKa = 10.52 RR3417 pKa = 11.84 SGRR3420 pKa = 11.84 EE3421 pKa = 3.76 ALPEE3425 pKa = 4.09 SASQVTSRR3433 pKa = 11.84 GFYY3436 pKa = 10.94 VMSNLDD3442 pKa = 3.44 KK3443 pKa = 10.89 NDD3445 pKa = 3.32 SVFRR3449 pKa = 11.84 DD3450 pKa = 3.2 WDD3452 pKa = 4.03 LKK3454 pKa = 10.32 TMSSKK3459 pKa = 10.61 IKK3461 pKa = 10.03 DD3462 pKa = 3.33 KK3463 pKa = 11.65 SMTVLDD3469 pKa = 3.98 ATPGFGGSVNYY3480 pKa = 10.22 LLQSMKK3486 pKa = 10.61 GGSLHH3491 pKa = 7.26 IYY3493 pKa = 9.47 QRR3495 pKa = 11.84 QKK3497 pKa = 11.39 DD3498 pKa = 3.91 PWPLKK3503 pKa = 10.44 EE3504 pKa = 6.06 DD3505 pKa = 5.17 LITPNINVKK3514 pKa = 9.83 VIRR3517 pKa = 11.84 SDD3519 pKa = 3.27 QFCYY3523 pKa = 10.41 KK3524 pKa = 10.44 EE3525 pKa = 4.04 EE3526 pKa = 3.93 EE3527 pKa = 4.13 FDD3529 pKa = 5.28 FVVCDD3534 pKa = 3.65 SVSDD3538 pKa = 3.43 IKK3540 pKa = 11.33 SIVSRR3545 pKa = 11.84 NDD3547 pKa = 2.96 KK3548 pKa = 10.92 EE3549 pKa = 5.57 FVLQCHH3555 pKa = 4.94 NVVRR3559 pKa = 11.84 QGGSFWVSCGLLDD3572 pKa = 4.38 ILNWPQEE3579 pKa = 4.28 LNCYY3583 pKa = 7.92 EE3584 pKa = 4.07 HH3585 pKa = 7.33 AKK3587 pKa = 10.28 FHH3589 pKa = 7.3 ISPTPNADD3597 pKa = 3.34 KK3598 pKa = 10.68 FYY3600 pKa = 10.68 FWVQLGGRR3608 pKa = 11.84 TTTRR3612 pKa = 11.84 KK3613 pKa = 9.31 IYY3615 pKa = 9.95 VNRR3618 pKa = 11.84 FYY3620 pKa = 11.33 GILCDD3625 pKa = 3.88 LVRR3628 pKa = 11.84 IHH3630 pKa = 7.12 LLKK3633 pKa = 10.8 LKK3635 pKa = 10.69 YY3636 pKa = 9.82 AVKK3639 pKa = 10.16 KK3640 pKa = 10.41 DD3641 pKa = 3.53 KK3642 pKa = 11.26 KK3643 pKa = 10.0 PVQLYY3648 pKa = 10.49 HH3649 pKa = 7.14 PVIQKK3654 pKa = 10.31 NKK3656 pKa = 8.17 TGAIPMINYY3665 pKa = 6.98 TQNIDD3670 pKa = 3.29 RR3671 pKa = 11.84 DD3672 pKa = 3.9 RR3673 pKa = 11.84 YY3674 pKa = 10.2 SEE3676 pKa = 4.11 MFEE3679 pKa = 4.11 MTNTSYY3685 pKa = 11.12 KK3686 pKa = 9.59 IRR3688 pKa = 11.84 HH3689 pKa = 5.89 RR3690 pKa = 11.84 LDD3692 pKa = 3.84 RR3693 pKa = 11.84 LDD3695 pKa = 4.04 SMRR3698 pKa = 11.84 KK3699 pKa = 7.75 QPRR3702 pKa = 11.84 LMKK3705 pKa = 10.5 SFSRR3709 pKa = 11.84 LQNFQFLTSVDD3720 pKa = 3.87 FKK3722 pKa = 11.14 RR3723 pKa = 11.84 GVRR3726 pKa = 11.84 LLPGKK3731 pKa = 9.92 LRR3733 pKa = 11.84 NQLIVATWDD3742 pKa = 3.24 QEE3744 pKa = 4.49 RR3745 pKa = 11.84 VKK3747 pKa = 10.07 VTSDD3751 pKa = 2.87 RR3752 pKa = 11.84 VLVSNVLSDD3761 pKa = 3.5 MLHH3764 pKa = 7.69 DD3765 pKa = 3.83 IFAVNWANTPITQVSKK3781 pKa = 10.95 DD3782 pKa = 3.46 LHH3784 pKa = 6.69 KK3785 pKa = 11.09 VDD3787 pKa = 3.54 MAIVDD3792 pKa = 3.99 RR3793 pKa = 11.84 LDD3795 pKa = 3.47 INNKK3799 pKa = 9.2 VLLDD3803 pKa = 3.79 SQVEE3807 pKa = 4.26 KK3808 pKa = 10.85 LLEE3811 pKa = 4.09 ASEE3814 pKa = 5.71 FILQPPDD3821 pKa = 3.54 RR3822 pKa = 11.84 LFKK3825 pKa = 10.72 LCTWEE3830 pKa = 4.07 EE3831 pKa = 3.94 LGTFINRR3838 pKa = 11.84 QGAAGMLDD3846 pKa = 4.06 DD3847 pKa = 4.02 VSKK3850 pKa = 10.58 MGEE3853 pKa = 4.19 LYY3855 pKa = 10.71 DD3856 pKa = 4.71 DD3857 pKa = 3.38 SRR3859 pKa = 11.84 TRR3861 pKa = 11.84 KK3862 pKa = 9.82 LCEE3865 pKa = 3.83 QIIGCLANGQDD3876 pKa = 3.59 CPLYY3880 pKa = 11.0 YY3881 pKa = 9.56 STCHH3885 pKa = 6.12 HH3886 pKa = 6.24 KK3887 pKa = 10.94 VEE3889 pKa = 4.7 SKK3891 pKa = 9.4 VSKK3894 pKa = 10.18 RR3895 pKa = 11.84 AVDD3898 pKa = 3.69 GKK3900 pKa = 10.72 IVDD3903 pKa = 4.05 TLPALLKK3910 pKa = 9.87 PVPRR3914 pKa = 11.84 LIQYY3918 pKa = 9.01 LSSYY3922 pKa = 10.14 ARR3924 pKa = 11.84 LVDD3927 pKa = 3.12 IWIFGSMMHH3936 pKa = 5.94 YY3937 pKa = 10.33 HH3938 pKa = 5.98 MKK3940 pKa = 10.18 VKK3942 pKa = 10.42 KK3943 pKa = 10.0 LYY3945 pKa = 9.96 KK3946 pKa = 9.99 YY3947 pKa = 10.67 SNTGTPITHH3956 pKa = 6.6 VGDD3959 pKa = 4.06 DD3960 pKa = 3.56 MHH3962 pKa = 7.09 AAWEE3966 pKa = 4.14 KK3967 pKa = 10.88 HH3968 pKa = 6.03 GGDD3971 pKa = 4.28 DD3972 pKa = 3.45 EE3973 pKa = 5.5 CIGVTGDD3980 pKa = 3.76 ASRR3983 pKa = 11.84 WDD3985 pKa = 3.8 HH3986 pKa = 6.37 NLGPSHH3992 pKa = 6.81 TYY3994 pKa = 9.7 VEE3996 pKa = 4.5 KK3997 pKa = 10.77 EE3998 pKa = 4.02 CVKK4001 pKa = 10.76 KK4002 pKa = 10.65 FFEE4005 pKa = 4.59 PSMHH4009 pKa = 6.8 KK4010 pKa = 10.07 IIEE4013 pKa = 4.05 TRR4015 pKa = 11.84 YY4016 pKa = 8.19 EE4017 pKa = 3.84 HH4018 pKa = 6.08 TAFPITFTDD4027 pKa = 2.67 MGYY4030 pKa = 10.75 AVSTAGQRR4038 pKa = 11.84 QSGDD4042 pKa = 3.5 YY4043 pKa = 8.67 LTSWGNGLIHH4053 pKa = 6.98 SLIQHH4058 pKa = 5.28 VCWSKK4063 pKa = 9.57 VLHH4066 pKa = 5.8 RR4067 pKa = 11.84 GVRR4070 pKa = 11.84 EE4071 pKa = 3.89 SHH4073 pKa = 6.55 EE4074 pKa = 4.31 DD4075 pKa = 3.6 LVEE4078 pKa = 3.99 HH4079 pKa = 6.87 RR4080 pKa = 11.84 VDD4082 pKa = 5.83 GDD4084 pKa = 4.56 DD4085 pKa = 3.45 NWHH4088 pKa = 5.87 MMNFRR4093 pKa = 11.84 HH4094 pKa = 5.88 ICVGRR4099 pKa = 11.84 EE4100 pKa = 3.37 KK4101 pKa = 11.31 DD4102 pKa = 4.21 KK4103 pKa = 11.23 FDD4105 pKa = 3.86 EE4106 pKa = 5.07 KK4107 pKa = 11.32 AKK4109 pKa = 10.3 LWEE4112 pKa = 4.62 KK4113 pKa = 10.37 IKK4115 pKa = 11.01 RR4116 pKa = 11.84 PGNLFDD4122 pKa = 5.48 KK4123 pKa = 10.64 EE4124 pKa = 4.14 PALSAEE4130 pKa = 3.89 ISFDD4134 pKa = 3.95 NILTRR4139 pKa = 11.84 VARR4142 pKa = 11.84 HH4143 pKa = 4.81 YY4144 pKa = 11.31 EE4145 pKa = 3.88 EE4146 pKa = 5.76 FGVKK4150 pKa = 9.59 LRR4152 pKa = 11.84 SGTHH4156 pKa = 4.57 TGFRR4160 pKa = 11.84 LHH4162 pKa = 6.0 YY4163 pKa = 9.88 QFSTVDD4169 pKa = 4.27 FLSHH4173 pKa = 7.09 TYY4175 pKa = 9.46 TEE4177 pKa = 4.11 IPIRR4181 pKa = 11.84 CIKK4184 pKa = 10.18 DD4185 pKa = 3.16 GNYY4188 pKa = 9.29 VQVRR4192 pKa = 11.84 KK4193 pKa = 9.55 YY4194 pKa = 11.01 LPVRR4198 pKa = 11.84 PYY4200 pKa = 11.13 SEE4202 pKa = 4.27 MFGKK4206 pKa = 10.74 LLFTLKK4212 pKa = 10.44 QGTSKK4217 pKa = 11.14 YY4218 pKa = 9.45 YY4219 pKa = 9.72 GAAIYY4224 pKa = 9.97 DD4225 pKa = 3.59 HH4226 pKa = 6.75 SRR4228 pKa = 11.84 GRR4230 pKa = 11.84 EE4231 pKa = 3.69 IAKK4234 pKa = 9.65 DD4235 pKa = 3.11 ACEE4238 pKa = 4.88 AIDD4241 pKa = 3.75 IQTSKK4246 pKa = 10.89 CMSYY4250 pKa = 10.68 LFQYY4254 pKa = 8.62 PHH4256 pKa = 6.3 VMCIRR4261 pKa = 11.84 EE4262 pKa = 3.91 FCLGVLSYY4270 pKa = 11.26 LGGPPSDD4277 pKa = 3.46 VKK4279 pKa = 10.96 KK4280 pKa = 9.67 WGSQFRR4286 pKa = 11.84 VTEE4289 pKa = 3.81 RR4290 pKa = 11.84 LAIDD4294 pKa = 3.53 KK4295 pKa = 10.62 VLAKK4299 pKa = 10.25 LDD4301 pKa = 3.65 EE4302 pKa = 4.4 VKK4304 pKa = 10.77 RR4305 pKa = 11.84 LDD4307 pKa = 3.6 WTCVEE4312 pKa = 3.93 PALRR4316 pKa = 11.84 QILDD4320 pKa = 3.73 LDD4322 pKa = 3.65 ITSLSDD4328 pKa = 2.66 IGTVSFEE4335 pKa = 4.16 QDD4337 pKa = 3.37 NFWKK4341 pKa = 9.87 EE4342 pKa = 3.56 QHH4344 pKa = 6.47 AEE4346 pKa = 3.89 NVALCARR4353 pKa = 11.84 EE4354 pKa = 4.04 YY4355 pKa = 10.73 KK4356 pKa = 10.16 IEE4358 pKa = 4.04 APRR4361 pKa = 11.84 FVHH4364 pKa = 6.3 SGDD4367 pKa = 3.44 YY4368 pKa = 9.59 MRR4370 pKa = 11.84 STRR4373 pKa = 11.84 IRR4375 pKa = 11.84 EE4376 pKa = 4.17 RR4377 pKa = 11.84 IVKK4380 pKa = 8.51 TVLHH4384 pKa = 5.76 QYY4386 pKa = 9.41 RR4387 pKa = 11.84 MCMARR4392 pKa = 11.84 KK4393 pKa = 8.54 GVTMRR4398 pKa = 11.84 EE4399 pKa = 3.93 QIAINPVIIPFWGYY4413 pKa = 11.1 LSMSPRR4419 pKa = 11.84 LLSVAKK4425 pKa = 10.34 IKK4427 pKa = 10.65 VKK4429 pKa = 10.55 KK4430 pKa = 9.8 QLSEE4434 pKa = 4.19 YY4435 pKa = 10.35 GVEE4438 pKa = 4.36 LEE4440 pKa = 4.86 PEE4442 pKa = 3.73 ILDD4445 pKa = 3.59 RR4446 pKa = 11.84 LVEE4449 pKa = 4.21 GVEE4452 pKa = 4.1 PKK4454 pKa = 10.54 KK4455 pKa = 9.66 QTEE4458 pKa = 4.16 SNEE4461 pKa = 3.87 RR4462 pKa = 11.84 MKK4464 pKa = 11.13 SFIEE4468 pKa = 3.92 QTGLFSVTSVAALRR4482 pKa = 11.84 QAGKK4486 pKa = 8.72 YY4487 pKa = 5.93 TVKK4490 pKa = 10.14 TGDD4493 pKa = 3.35 HH4494 pKa = 5.99 TVTFSNVYY4502 pKa = 10.33 NDD4504 pKa = 3.54 AFGSGFQILSLRR4516 pKa = 11.84 KK4517 pKa = 9.96 LFGIPINCAAEE4528 pKa = 4.3 TVEE4531 pKa = 5.45 DD4532 pKa = 3.8 LQFTKK4537 pKa = 10.52 RR4538 pKa = 11.84 FLEE4541 pKa = 4.18 AQPAVRR4547 pKa = 11.84 VADD4550 pKa = 3.79 GFEE4553 pKa = 3.98 FQSMYY4558 pKa = 10.99 EE4559 pKa = 4.11 EE4560 pKa = 4.27 TRR4562 pKa = 11.84 PRR4564 pKa = 11.84 PDD4566 pKa = 2.59 KK4567 pKa = 9.18 TTTFEE4572 pKa = 3.98 IEE4574 pKa = 4.16 TVKK4577 pKa = 11.09 NILFKK4582 pKa = 10.64 RR4583 pKa = 11.84 YY4584 pKa = 9.27 GLSRR4588 pKa = 11.84 CEE4590 pKa = 3.75 TVFILNQLEE4599 pKa = 4.32 PAVLQHH4605 pKa = 6.25 NRR4607 pKa = 11.84 GKK4609 pKa = 10.75 VYY4611 pKa = 10.56 LRR4613 pKa = 11.84 SDD4615 pKa = 3.27 VGDD4618 pKa = 3.44 EE4619 pKa = 3.98 EE4620 pKa = 3.99 NFYY4623 pKa = 10.87 RR4624 pKa = 11.84 FKK4626 pKa = 10.97 LCYY4629 pKa = 9.41 IDD4631 pKa = 3.53 CTKK4634 pKa = 10.71 IKK4636 pKa = 10.25 LKK4638 pKa = 10.35 RR4639 pKa = 11.84 AGVFMRR4645 pKa = 11.84 SVVEE4649 pKa = 4.96 RR4650 pKa = 11.84 EE4651 pKa = 4.04 DD4652 pKa = 3.44 LSKK4655 pKa = 10.86 LVEE4658 pKa = 4.31 RR4659 pKa = 11.84 VGTLPVGSSCVVKK4672 pKa = 10.5 VDD4674 pKa = 3.19 KK4675 pKa = 10.81 TFLHH4679 pKa = 6.78 AVTIDD4684 pKa = 3.88 LDD4686 pKa = 3.98 SLSEE4690 pKa = 4.04 LFSVQEE4696 pKa = 3.96 IFRR4699 pKa = 11.84 SPFTGGSSEE4708 pKa = 4.18 LYY4710 pKa = 10.0 IYY4712 pKa = 10.73 FGGKK4716 pKa = 9.51 GLQQEE4721 pKa = 4.77 VKK4723 pKa = 9.86 VSRR4726 pKa = 11.84 IGNVEE4731 pKa = 3.88 AASCVPLRR4739 pKa = 11.84 EE4740 pKa = 3.85 QVAIFLKK4747 pKa = 11.03 LLLQSNHH4754 pKa = 6.42 LNMNKK4759 pKa = 9.63 NLASAVYY4766 pKa = 9.7 SGTSAFSDD4774 pKa = 3.33 EE4775 pKa = 4.56 HH4776 pKa = 7.73 VGILARR4782 pKa = 11.84 EE4783 pKa = 3.83 NAMIPFCTKK4792 pKa = 10.04 KK4793 pKa = 10.74 KK4794 pKa = 9.85 FDD4796 pKa = 4.12 LRR4798 pKa = 11.84 VKK4800 pKa = 10.24 QYY4802 pKa = 10.59 EE4803 pKa = 3.7 PGMRR4807 pKa = 11.84 FGVQGPLAIWQYY4819 pKa = 10.34 FVHH4822 pKa = 7.12 PSLVHH4827 pKa = 5.55 WFYY4830 pKa = 11.44 NAYY4833 pKa = 9.27 EE4834 pKa = 4.09 NEE4836 pKa = 4.13 MDD4838 pKa = 4.04 GKK4840 pKa = 10.57 RR4841 pKa = 11.84 RR4842 pKa = 11.84 DD4843 pKa = 3.73 VKK4845 pKa = 11.26 VMSSVPRR4852 pKa = 11.84 LLVPPSFKK4860 pKa = 10.57 LGKK4863 pKa = 10.23 LKK4865 pKa = 10.49 IEE4867 pKa = 4.42 FEE4869 pKa = 4.19 TDD4871 pKa = 2.59 LGKK4874 pKa = 10.8 EE4875 pKa = 4.01 DD4876 pKa = 4.33 FVRR4879 pKa = 11.84 DD4880 pKa = 3.89 SDD4882 pKa = 4.55 TNWLRR4887 pKa = 11.84 DD4888 pKa = 3.51 YY4889 pKa = 11.18 VIAKK4893 pKa = 9.06 TEE4895 pKa = 4.36 DD4896 pKa = 3.21 STLDD4900 pKa = 3.4 PKK4902 pKa = 10.6 HH4903 pKa = 6.45 ARR4905 pKa = 11.84 FRR4907 pKa = 11.84 NPVKK4911 pKa = 10.4 KK4912 pKa = 9.49 WIKK4915 pKa = 10.7 LDD4917 pKa = 3.46 VDD4919 pKa = 4.57 DD4920 pKa = 4.54 NTEE4923 pKa = 4.11 KK4924 pKa = 10.84 PSVAQFSYY4932 pKa = 8.0 QTCIRR4937 pKa = 11.84 ICQIISDD4944 pKa = 4.1 IGSKK4948 pKa = 10.8 NIVCEE4953 pKa = 4.29 IDD4955 pKa = 3.47 PDD4957 pKa = 4.0 DD4958 pKa = 5.29 DD4959 pKa = 4.31 GRR4961 pKa = 11.84 FTYY4964 pKa = 9.96 VFNYY4968 pKa = 7.64 LQCGKK4973 pKa = 9.47 VHH4975 pKa = 6.64 VDD4977 pKa = 3.19 RR4978 pKa = 11.84 EE4979 pKa = 4.35 KK4980 pKa = 11.06 PLLQALRR4987 pKa = 11.84 KK4988 pKa = 9.22 VGEE4991 pKa = 4.11 RR4992 pKa = 11.84 MSLRR4996 pKa = 11.84 EE4997 pKa = 3.65 THH4999 pKa = 6.58 EE5000 pKa = 4.17 PANLCVTRR5008 pKa = 11.84 NLSKK5012 pKa = 10.9 SYY5014 pKa = 10.12 DD5015 pKa = 3.48 RR5016 pKa = 11.84 KK5017 pKa = 10.68 YY5018 pKa = 10.73 VICVGNTSKK5027 pKa = 10.9 LDD5029 pKa = 3.53 EE5030 pKa = 4.01 VRR5032 pKa = 11.84 RR5033 pKa = 11.84 RR5034 pKa = 11.84 ARR5036 pKa = 11.84 HH5037 pKa = 4.61 VYY5039 pKa = 8.5 TRR5041 pKa = 11.84 FVEE5044 pKa = 4.52 TPILNEE5050 pKa = 3.88 QILLVSFRR5058 pKa = 11.84 EE5059 pKa = 3.99 VNITKK5064 pKa = 10.36 KK5065 pKa = 10.77 KK5066 pKa = 9.68 NLPPMRR5072 pKa = 11.84 SNRR5075 pKa = 11.84 IEE5077 pKa = 4.17 PLDD5080 pKa = 3.42 VNYY5083 pKa = 10.69 SVKK5086 pKa = 10.49 RR5087 pKa = 11.84 CVSYY5091 pKa = 10.29 DD5092 pKa = 2.95 HH5093 pKa = 6.7 RR5094 pKa = 11.84 QIDD5097 pKa = 3.45 ISKK5100 pKa = 10.21 KK5101 pKa = 9.47 KK5102 pKa = 10.25 LHH5104 pKa = 5.06 THH5106 pKa = 6.0 ICISCQTEE5114 pKa = 3.94 YY5115 pKa = 11.6 ASFHH5119 pKa = 7.19 DD5120 pKa = 3.78 ITRR5123 pKa = 11.84 QNHH5126 pKa = 5.12 GKK5128 pKa = 9.39 LCYY5131 pKa = 8.69 MCALQVYY5138 pKa = 8.31 IQRR5141 pKa = 11.84 EE5142 pKa = 4.18 KK5143 pKa = 10.37 EE5144 pKa = 4.24 AKK5146 pKa = 9.81 FQLNLDD5152 pKa = 3.54 RR5153 pKa = 11.84 HH5154 pKa = 6.29 DD5155 pKa = 4.5 NPVTDD5160 pKa = 4.13 HH5161 pKa = 6.72 FFDD5164 pKa = 4.4 VIAGAVRR5171 pKa = 11.84 EE5172 pKa = 4.03 YY5173 pKa = 11.26 LNEE5176 pKa = 3.99 LFNRR5180 pKa = 11.84 ALIMPMYY5187 pKa = 7.14 EE5188 pKa = 3.47 TWVWRR5193 pKa = 11.84 FTYY5196 pKa = 10.31 SRR5198 pKa = 11.84 AFAAPLIKK5206 pKa = 10.38 KK5207 pKa = 9.51 ILSPLLGFVFLMLMTGCGRR5226 pKa = 11.84 IGFGLLLVTMWLMAQFVPIVYY5247 pKa = 9.45 KK5248 pKa = 10.48 ISYY5251 pKa = 9.13 AEE5253 pKa = 3.89 VVMGVAGYY5261 pKa = 10.75 RR5262 pKa = 11.84 MPAEE5266 pKa = 4.13 STYY5269 pKa = 11.41 LLAFIFGLSFMTYY5282 pKa = 9.97 SAFDD5286 pKa = 3.64 LVKK5289 pKa = 10.67 LVLHH5293 pKa = 6.47 PFYY5296 pKa = 11.06 YY5297 pKa = 10.55 LWPSNWVDD5305 pKa = 2.92 ILSIVIFNPGVRR5317 pKa = 11.84 RR5318 pKa = 11.84 TDD5320 pKa = 3.02 RR5321 pKa = 11.84 YY5322 pKa = 9.97 IWNLCTLPIRR5332 pKa = 11.84 ITFDD5336 pKa = 2.74 TLYY5339 pKa = 10.85 YY5340 pKa = 9.03 LTKK5343 pKa = 10.72 SLLTYY5348 pKa = 10.46 LISFEE5353 pKa = 5.5 KK5354 pKa = 9.6 GRR5356 pKa = 11.84 QWATEE5361 pKa = 3.2 ISLRR5365 pKa = 11.84 HH5366 pKa = 4.56 ARR5368 pKa = 11.84 FRR5370 pKa = 11.84 EE5371 pKa = 3.86 FAQDD5375 pKa = 3.47 CFGPAARR5382 pKa = 11.84 RR5383 pKa = 11.84 AYY5385 pKa = 10.38 GIRR5388 pKa = 11.84 NYY5390 pKa = 10.78 YY5391 pKa = 10.43 NNLTRR5396 pKa = 11.84 DD5397 pKa = 3.61 FEE5399 pKa = 4.68 GANTASFYY5407 pKa = 10.78 FFYY5410 pKa = 11.13 YY5411 pKa = 10.47 FLNHH5415 pKa = 6.59 DD5416 pKa = 3.68 QVIVKK5421 pKa = 9.6 LYY5423 pKa = 8.58 VAVFFVLYY5431 pKa = 10.7 AHH5433 pKa = 6.43 FTGRR5437 pKa = 11.84 FNKK5440 pKa = 9.68 YY5441 pKa = 7.08 VQILRR5446 pKa = 11.84 LYY5448 pKa = 10.14 IIYY5451 pKa = 8.25 STHH5454 pKa = 6.72 WLNLWQDD5461 pKa = 3.4 PSQIVFNSLKK5471 pKa = 11.0 SNMLLEE5477 pKa = 4.26 LFGMGSDD5484 pKa = 3.51 SLGGISVKK5492 pKa = 9.94 TIPSFSTSTDD5502 pKa = 3.14 LKK5504 pKa = 10.96 LAACLILILLFVTLVDD5520 pKa = 4.93 FYY5522 pKa = 11.19 ISFYY5526 pKa = 10.45 QALAGTNALGPFCQYY5541 pKa = 10.82 VEE5543 pKa = 4.44 ALPEE5547 pKa = 3.85 FLNYY5551 pKa = 10.07 HH5552 pKa = 6.39 YY5553 pKa = 10.64 YY5554 pKa = 8.42 QTLEE5558 pKa = 3.71 YY5559 pKa = 10.29 LKK5561 pKa = 10.7 FIFYY5565 pKa = 10.24 FLVGCTIITLRR5576 pKa = 11.84 IIFRR5580 pKa = 11.84 NQFTEE5585 pKa = 3.92 ALFNRR5590 pKa = 11.84 AALHH5594 pKa = 6.77 ISAQYY5599 pKa = 9.9 RR5600 pKa = 11.84 NHH5602 pKa = 6.8 ISRR5605 pKa = 11.84 LIYY5608 pKa = 9.92 PYY5610 pKa = 10.83 VAVLGNILHH5619 pKa = 5.92 QFGIIDD5625 pKa = 3.7 FTGLANLQIILFAFHH5640 pKa = 6.91 WAGVGYY5646 pKa = 10.13 ISDD5649 pKa = 4.19 DD5650 pKa = 3.93 ADD5652 pKa = 3.72 PTIHH5656 pKa = 6.95 WSITLVMCLFKK5667 pKa = 11.05 LIGFSPYY5674 pKa = 8.37 VTLVLVLIIFGPVIHH5689 pKa = 6.69 FFGFEE5694 pKa = 4.67 LIRR5697 pKa = 11.84 YY5698 pKa = 8.72 LSLQTAIRR5706 pKa = 11.84 GMFNLCRR5713 pKa = 11.84 NTFIHH5718 pKa = 6.97 NILFVCVISNLTGTIHH5734 pKa = 6.42 PVVTVGVIILLKK5746 pKa = 10.43 HH5747 pKa = 4.33 LTEE5750 pKa = 5.09 RR5751 pKa = 11.84 YY5752 pKa = 10.05 SFLLPSRR5759 pKa = 11.84 RR5760 pKa = 11.84 TVANLFVLDD5769 pKa = 3.74 SFLFVLMYY5777 pKa = 8.19 NTWAFFDD5784 pKa = 3.9 LQPTFVLEE5792 pKa = 4.28 YY5793 pKa = 8.84 IWRR5796 pKa = 11.84 FLFQFYY5802 pKa = 10.15 IGQPPGSS5809 pKa = 3.66
Molecular weight: 665.05 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 6.792
IPC2_protein 7.102
IPC_protein 6.898
Toseland 6.722
ProMoST 7.512
Dawson 7.571
Bjellqvist 8.039
Wikipedia 7.483
Rodwell 7.585
Grimsley 6.795
Solomon 7.571
Lehninger 7.585
Nozaki 8.244
DTASelect 7.775
Thurlkill 7.819
EMBOSS 7.805
Sillero 8.126
Patrickios 4.062
IPC_peptide 7.571
IPC2_peptide 7.234
IPC2.peptide.svr19 7.066
Protein with the highest isoelectric point:
>tr|A0A0P0QKJ0|A0A0P0QKJ0_9VIRU Polyprotein OS=Beihai barnacle viurs 1 OX=1746057 PE=4 SV=1
MM1 pKa = 7.16 TKK3 pKa = 8.83 KK4 pKa = 8.44 TVQRR8 pKa = 11.84 RR9 pKa = 11.84 VVSDD13 pKa = 3.48 SLFEE17 pKa = 4.08 FVLPARR23 pKa = 11.84 VRR25 pKa = 11.84 DD26 pKa = 3.88 TGSVKK31 pKa = 10.81 AKK33 pKa = 10.04 VSCDD37 pKa = 3.42 LPYY40 pKa = 10.27 VTLDD44 pKa = 3.55 DD45 pKa = 3.95 EE46 pKa = 4.74 RR47 pKa = 11.84 VLAEE51 pKa = 3.92 EE52 pKa = 4.54 HH53 pKa = 7.06 DD54 pKa = 4.4 EE55 pKa = 4.18 KK56 pKa = 10.64 TSRR59 pKa = 11.84 QRR61 pKa = 11.84 DD62 pKa = 3.51 EE63 pKa = 3.78 ASKK66 pKa = 10.37 RR67 pKa = 11.84 RR68 pKa = 11.84 SGRR71 pKa = 11.84 EE72 pKa = 3.8 FRR74 pKa = 11.84 WGAAVAKK81 pKa = 10.27 RR82 pKa = 11.84 RR83 pKa = 11.84 LEE85 pKa = 3.95 EE86 pKa = 3.82 EE87 pKa = 4.11 AYY89 pKa = 10.07 EE90 pKa = 4.56 LYY92 pKa = 10.82 DD93 pKa = 5.49 LEE95 pKa = 4.52 TEE97 pKa = 3.93 ADD99 pKa = 3.42 KK100 pKa = 11.4 ARR102 pKa = 11.84 SRR104 pKa = 11.84 RR105 pKa = 11.84 YY106 pKa = 8.66 QQLVYY111 pKa = 10.57 DD112 pKa = 4.23 RR113 pKa = 11.84 SFAARR118 pKa = 11.84 CGEE121 pKa = 4.15 LDD123 pKa = 3.42 ALLAIEE129 pKa = 4.94 VKK131 pKa = 10.46 RR132 pKa = 11.84 QALVDD137 pKa = 3.54 QAIADD142 pKa = 4.32 LEE144 pKa = 4.29 QVGAYY149 pKa = 9.31 RR150 pKa = 11.84 RR151 pKa = 11.84 AEE153 pKa = 3.84 AAKK156 pKa = 10.28 LRR158 pKa = 11.84 EE159 pKa = 3.96 DD160 pKa = 3.67 AYY162 pKa = 10.33 FAEE165 pKa = 5.0 RR166 pKa = 11.84 LGEE169 pKa = 4.08 LDD171 pKa = 4.66 ALISQLGAEE180 pKa = 4.75 LSYY183 pKa = 11.51 AQGQYY188 pKa = 11.01 DD189 pKa = 4.72 AIYY192 pKa = 9.7 CSEE195 pKa = 4.05 EE196 pKa = 3.87 AVEE199 pKa = 4.59 IDD201 pKa = 4.03 CDD203 pKa = 3.78 TKK205 pKa = 10.86 RR206 pKa = 11.84 GEE208 pKa = 4.09 FLAASTEE215 pKa = 4.02 YY216 pKa = 11.11 DD217 pKa = 2.83 EE218 pKa = 4.6 TMRR221 pKa = 11.84 LKK223 pKa = 10.97 KK224 pKa = 9.48 EE225 pKa = 4.03 VNRR228 pKa = 11.84 IRR230 pKa = 11.84 HH231 pKa = 4.83 AQRR234 pKa = 11.84 KK235 pKa = 7.48 RR236 pKa = 11.84 GYY238 pKa = 10.46 YY239 pKa = 9.76 GVNDD243 pKa = 4.34 EE244 pKa = 4.86 GWLIACGSGRR254 pKa = 11.84 SKK256 pKa = 11.19 DD257 pKa = 3.77 DD258 pKa = 3.41 CEE260 pKa = 4.82 KK261 pKa = 11.05 CIEE264 pKa = 4.12 THH266 pKa = 6.1 NAFEE270 pKa = 4.21 VLEE273 pKa = 4.2 CQPLPEE279 pKa = 5.25 RR280 pKa = 11.84 DD281 pKa = 3.36 SDD283 pKa = 4.7 GEE285 pKa = 4.25 VPKK288 pKa = 11.07 NGEE291 pKa = 3.88 QKK293 pKa = 10.57 RR294 pKa = 11.84 LRR296 pKa = 11.84 KK297 pKa = 9.47 VVRR300 pKa = 11.84 KK301 pKa = 8.94 PKK303 pKa = 10.24 RR304 pKa = 11.84 ADD306 pKa = 3.36 NFDD309 pKa = 3.62 EE310 pKa = 5.09 LMAEE314 pKa = 3.96 AAKK317 pKa = 10.1 WNAEE321 pKa = 4.08 CEE323 pKa = 4.39 KK324 pKa = 10.79 QGATLMPSRR333 pKa = 11.84 AAYY336 pKa = 8.97 EE337 pKa = 4.15 AIARR341 pKa = 11.84 KK342 pKa = 9.18 RR343 pKa = 11.84 VRR345 pKa = 11.84 SFGVRR350 pKa = 11.84 GEE352 pKa = 4.21 EE353 pKa = 4.03 KK354 pKa = 10.59 QEE356 pKa = 3.94 LLLIASNTVEE366 pKa = 4.12 VVEE369 pKa = 5.2 RR370 pKa = 11.84 LTKK373 pKa = 10.91 ANGSSGKK380 pKa = 7.16 EE381 pKa = 3.77 TKK383 pKa = 9.67 EE384 pKa = 3.77 EE385 pKa = 3.83 KK386 pKa = 9.87 FRR388 pKa = 11.84 RR389 pKa = 11.84 AFGKK393 pKa = 10.09 QGEE396 pKa = 4.29 ILYY399 pKa = 10.52 EE400 pKa = 3.96 SGKK403 pKa = 9.9 WYY405 pKa = 10.46 LRR407 pKa = 11.84 RR408 pKa = 11.84 CNHH411 pKa = 5.65 TFGTSVQNGDD421 pKa = 3.67 IQWFALTLRR430 pKa = 11.84 KK431 pKa = 9.76 GVAIKK436 pKa = 9.89 TEE438 pKa = 3.97 AKK440 pKa = 9.93 APRR443 pKa = 11.84 FGSYY447 pKa = 9.91 YY448 pKa = 9.99 EE449 pKa = 4.42 HH450 pKa = 7.26 GAMMWYY456 pKa = 8.65 QNKK459 pKa = 9.07 VEE461 pKa = 4.11 RR462 pKa = 11.84 CGLVEE467 pKa = 4.18 VSCLEE472 pKa = 3.82 ASRR475 pKa = 11.84 LKK477 pKa = 10.89 GKK479 pKa = 10.46 SGTNCFGGTLLGVIHH494 pKa = 7.55 DD495 pKa = 4.35 IDD497 pKa = 3.91 YY498 pKa = 10.36 DD499 pKa = 4.1 YY500 pKa = 11.48 YY501 pKa = 11.23 GAVIHH506 pKa = 6.41 TSDD509 pKa = 3.69 PVEE512 pKa = 4.41 EE513 pKa = 4.15 IQYY516 pKa = 10.62 HH517 pKa = 5.59 VDD519 pKa = 3.5 HH520 pKa = 7.15 HH521 pKa = 7.33 DD522 pKa = 3.44 DD523 pKa = 3.15 WVDD526 pKa = 2.87 IGRR529 pKa = 11.84 SFGEE533 pKa = 3.94 EE534 pKa = 3.74 RR535 pKa = 11.84 GKK537 pKa = 8.12 MTYY540 pKa = 9.07 TPCSKK545 pKa = 9.5 TALTFMCLLSSVFSCEE561 pKa = 4.11 VVSEE565 pKa = 4.17 IYY567 pKa = 9.07 GTYY570 pKa = 10.15 LVNEE574 pKa = 4.47 IQQLDD579 pKa = 3.77 WPSGEE584 pKa = 4.39 TEE586 pKa = 4.85 CMIPPCIGCSDD597 pKa = 4.37 LEE599 pKa = 4.56 CGVGYY604 pKa = 10.61 DD605 pKa = 3.73 LATWQYY611 pKa = 10.58 ICNQADD617 pKa = 3.57 LCIEE621 pKa = 4.09 SEE623 pKa = 4.28 ALVMLFNSNYY633 pKa = 10.37 SVDD636 pKa = 4.54 LDD638 pKa = 4.02 CMYY641 pKa = 8.56 NTPRR645 pKa = 11.84 QRR647 pKa = 11.84 TKK649 pKa = 10.84 RR650 pKa = 11.84 DD651 pKa = 3.27 TSSSDD656 pKa = 3.1 EE657 pKa = 4.39 TFSSLVNKK665 pKa = 10.46 FGFDD669 pKa = 3.03 ASAIKK674 pKa = 10.36 EE675 pKa = 4.15 KK676 pKa = 10.25 ATSFKK681 pKa = 11.09 DD682 pKa = 3.25 KK683 pKa = 10.61 VVEE686 pKa = 3.84 YY687 pKa = 10.08 SRR689 pKa = 11.84 NSIVIAVTILLFWLSLTLLGVSPVVSMIFIVLSFYY724 pKa = 10.55 ISSVQSVNIAKK735 pKa = 10.32 DD736 pKa = 3.32 RR737 pKa = 11.84 TNCRR741 pKa = 11.84 IEE743 pKa = 3.91 YY744 pKa = 9.19 RR745 pKa = 11.84 KK746 pKa = 9.65 PDD748 pKa = 3.27 LTVRR752 pKa = 11.84 SGCATNTRR760 pKa = 11.84 MFSGVIFCNQTGVSGCGWYY779 pKa = 8.14 ITFGNFKK786 pKa = 10.49 SDD788 pKa = 2.75 MRR790 pKa = 11.84 TRR792 pKa = 11.84 ALSCVSDD799 pKa = 3.82 DD800 pKa = 4.88 QMKK803 pKa = 9.94 FWIEE807 pKa = 3.58 QTPTQKK813 pKa = 10.15 FVRR816 pKa = 11.84 SYY818 pKa = 10.97 CAANPLDD825 pKa = 3.71 IVGLTRR831 pKa = 11.84 KK832 pKa = 9.16 VVEE835 pKa = 4.29 YY836 pKa = 10.74 YY837 pKa = 10.5 FGYY840 pKa = 10.02 LQEE843 pKa = 4.44 PSEE846 pKa = 4.13 AHH848 pKa = 6.48 LKK850 pKa = 10.39 RR851 pKa = 11.84 ISDD854 pKa = 3.64 EE855 pKa = 4.28 FSRR858 pKa = 11.84 TMTHH862 pKa = 7.55 LLGTKK867 pKa = 9.95 YY868 pKa = 10.79 YY869 pKa = 9.81 EE870 pKa = 3.9 ILYY873 pKa = 8.52 KK874 pKa = 10.26 ICVGVICLVALLILPFPLGAIVAIMFVSVYY904 pKa = 9.48 IAEE907 pKa = 4.43 AASVCQTSMVMTQSGLQYY925 pKa = 10.55 HH926 pKa = 6.06 VGGLEE931 pKa = 3.91 KK932 pKa = 10.01 TVTRR936 pKa = 11.84 GKK938 pKa = 10.45 VKK940 pKa = 10.38 VSRR943 pKa = 11.84 GFCLRR948 pKa = 11.84 WHH950 pKa = 6.36 EE951 pKa = 4.33 KK952 pKa = 8.26 EE953 pKa = 4.29 TVVVDD958 pKa = 3.75 NVQSEE963 pKa = 4.72 VFTQHH968 pKa = 7.07 KK969 pKa = 10.13 IDD971 pKa = 5.24 VLDD974 pKa = 3.5 QTPNFHH980 pKa = 5.95 TTDD983 pKa = 2.66 IVRR986 pKa = 11.84 IVATPKK992 pKa = 9.57 IDD994 pKa = 3.46 HH995 pKa = 6.49 LCSYY999 pKa = 9.76 RR1000 pKa = 11.84 CKK1002 pKa = 10.62 KK1003 pKa = 10.22 SWLDD1007 pKa = 3.19 TFEE1010 pKa = 5.25 RR1011 pKa = 11.84 EE1012 pKa = 3.69 EE1013 pKa = 3.97 RR1014 pKa = 11.84 LISGGAYY1021 pKa = 9.76 VYY1023 pKa = 10.78 KK1024 pKa = 10.3 CNRR1027 pKa = 11.84 WTRR1030 pKa = 11.84 EE1031 pKa = 3.38 RR1032 pKa = 11.84 KK1033 pKa = 10.08 LYY1035 pKa = 9.54 WGSSWDD1041 pKa = 3.28 ASYY1044 pKa = 11.05 EE1045 pKa = 4.14 HH1046 pKa = 7.01 YY1047 pKa = 10.97 DD1048 pKa = 2.81 GWTCNGCPGASYY1060 pKa = 10.86 SFKK1063 pKa = 10.58 KK1064 pKa = 10.2 SCIYY1068 pKa = 9.54 WKK1070 pKa = 10.73 RR1071 pKa = 11.84 EE1072 pKa = 3.99 DD1073 pKa = 3.35 EE1074 pKa = 4.94 CVFQNKK1080 pKa = 8.69 IVEE1083 pKa = 4.35 SLTMKK1088 pKa = 9.97 VRR1090 pKa = 11.84 YY1091 pKa = 7.06 TKK1093 pKa = 11.12 NEE1095 pKa = 3.81 VEE1097 pKa = 4.26 EE1098 pKa = 4.71 DD1099 pKa = 3.41 RR1100 pKa = 11.84 VFTVTRR1106 pKa = 11.84 DD1107 pKa = 3.33 SPFTLGGVTFHH1118 pKa = 6.94 LLSHH1122 pKa = 6.1 KK1123 pKa = 9.93 HH1124 pKa = 5.35 IKK1126 pKa = 10.18 YY1127 pKa = 10.52 DD1128 pKa = 4.43 VINCQDD1134 pKa = 2.98 RR1135 pKa = 11.84 KK1136 pKa = 10.77 YY1137 pKa = 10.98 LVNDD1141 pKa = 4.43 RR1142 pKa = 11.84 SAIPQDD1148 pKa = 3.41 VIQYY1152 pKa = 9.13 NEE1154 pKa = 3.81 KK1155 pKa = 10.66 SEE1157 pKa = 3.82 ITEE1160 pKa = 3.83 RR1161 pKa = 11.84 YY1162 pKa = 9.36 LFSRR1166 pKa = 11.84 CSTHH1170 pKa = 6.03 YY1171 pKa = 10.27 VCKK1174 pKa = 10.02 TYY1176 pKa = 11.27 SNSCNDD1182 pKa = 3.33 KK1183 pKa = 11.13 NGAICTWKK1191 pKa = 10.6 SLTHH1195 pKa = 6.49 AMPPRR1200 pKa = 11.84 SLSEE1204 pKa = 3.94 TTMLIHH1210 pKa = 7.26 PEE1212 pKa = 3.9 AKK1214 pKa = 8.71 QTWGHH1219 pKa = 6.19 FEE1221 pKa = 4.43 LLVSGQVTEE1230 pKa = 4.2 TTICKK1235 pKa = 8.4 TFRR1238 pKa = 11.84 VHH1240 pKa = 4.92 PTGRR1244 pKa = 11.84 VDD1246 pKa = 4.22 FTTSSSGFVEE1256 pKa = 5.08 FTFDD1260 pKa = 3.48 AHH1262 pKa = 7.04 KK1263 pKa = 10.56 LPCIPEE1269 pKa = 4.14 LNAIDD1274 pKa = 4.46 SDD1276 pKa = 3.93 EE1277 pKa = 4.9 CEE1279 pKa = 4.25 VTILRR1284 pKa = 11.84 PTLTDD1289 pKa = 3.02 NATEE1293 pKa = 3.78 VSMGVTCRR1301 pKa = 11.84 RR1302 pKa = 11.84 VQVANFSVDD1311 pKa = 3.11 GQQVVATVRR1320 pKa = 11.84 YY1321 pKa = 9.94 VKK1323 pKa = 10.42 FANYY1327 pKa = 10.36 DD1328 pKa = 3.75 LLEE1331 pKa = 4.31 NAAIEE1336 pKa = 4.57 FWSSGGEE1343 pKa = 3.37 IGSFGEE1349 pKa = 5.12 AISDD1353 pKa = 3.46 WFHH1356 pKa = 5.29 QTFSFKK1362 pKa = 9.92 WPNLRR1367 pKa = 11.84 EE1368 pKa = 3.97 IGVKK1372 pKa = 10.0 VLIVLVIYY1380 pKa = 8.37 MVSPPLAIFVVIFYY1394 pKa = 9.1 FLINGAFAVEE1404 pKa = 4.62 GNCYY1408 pKa = 10.39 GYY1410 pKa = 10.68 VANSNGRR1417 pKa = 11.84 TIMNKK1422 pKa = 7.74 WLYY1425 pKa = 10.46 EE1426 pKa = 3.8 KK1427 pKa = 10.49 GISYY1431 pKa = 7.65 NTHH1434 pKa = 5.25 GFFFGGIPDD1443 pKa = 3.92 SACDD1447 pKa = 3.48 SRR1449 pKa = 11.84 RR1450 pKa = 11.84 GQIVKK1455 pKa = 9.28 EE1456 pKa = 3.98 KK1457 pKa = 10.09 CDD1459 pKa = 3.43 QILYY1463 pKa = 10.22 RR1464 pKa = 11.84 LEE1466 pKa = 3.93 SLKK1469 pKa = 10.24 WYY1471 pKa = 10.61 SNSPVNDD1478 pKa = 3.57 RR1479 pKa = 11.84 LNDD1482 pKa = 3.25 VTCRR1486 pKa = 11.84 HH1487 pKa = 6.77 EE1488 pKa = 4.21 YY1489 pKa = 9.76 CKK1491 pKa = 10.6 HH1492 pKa = 6.3 GIGADD1497 pKa = 3.64 LSFEE1501 pKa = 4.32 EE1502 pKa = 4.51 YY1503 pKa = 10.73 VDD1505 pKa = 6.13 LIEE1508 pKa = 5.72 DD1509 pKa = 3.88 CAKK1512 pKa = 10.39 TSVTKK1517 pKa = 9.92 IWYY1520 pKa = 8.77 PRR1522 pKa = 11.84 EE1523 pKa = 3.8 CTKK1526 pKa = 11.11 NVINEE1531 pKa = 3.87 VTTNKK1536 pKa = 9.95 SANINCPVNGLVLNGKK1552 pKa = 7.64 EE1553 pKa = 4.19 VIVPFSVAGGEE1564 pKa = 4.1 RR1565 pKa = 11.84 EE1566 pKa = 4.2 TVSFYY1571 pKa = 10.59 IKK1573 pKa = 10.52 LVIVYY1578 pKa = 8.76 VVLSVLFVNLEE1589 pKa = 3.9 MPDD1592 pKa = 3.69 INNLAALCHH1601 pKa = 5.98 NPAFEE1606 pKa = 4.52 LLVDD1610 pKa = 3.65 ITCIVLNPLNLMVLLLVKK1628 pKa = 10.31 RR1629 pKa = 11.84 LHH1631 pKa = 7.33 LSFCCSCLVIIFASVVEE1648 pKa = 4.19 NTLIALVTAFVRR1660 pKa = 11.84 IAAMVYY1666 pKa = 9.6 SKK1668 pKa = 10.62 SIHH1671 pKa = 5.92 FPFVASNIEE1680 pKa = 3.98 YY1681 pKa = 5.87 WTKK1684 pKa = 10.53 YY1685 pKa = 10.23 DD1686 pKa = 4.32 DD1687 pKa = 4.02 RR1688 pKa = 11.84 GSLFTSPASKK1698 pKa = 10.19 VVKK1701 pKa = 9.99 SICDD1705 pKa = 3.33 SGCQTEE1711 pKa = 4.42 GNMVVQSCDD1720 pKa = 2.98 IVLEE1724 pKa = 4.4 RR1725 pKa = 11.84 YY1726 pKa = 9.37 NGVWIRR1732 pKa = 11.84 KK1733 pKa = 7.06 EE1734 pKa = 3.7 LHH1736 pKa = 6.39 SEE1738 pKa = 4.21 DD1739 pKa = 3.95 IEE1741 pKa = 4.09 PLARR1745 pKa = 11.84 EE1746 pKa = 4.44 DD1747 pKa = 5.09 CPVDD1751 pKa = 3.61 PYY1753 pKa = 11.26 KK1754 pKa = 10.73 YY1755 pKa = 9.32 EE1756 pKa = 4.23 CGIKK1760 pKa = 9.99 ISVSKK1765 pKa = 10.03 TSDD1768 pKa = 3.71 DD1769 pKa = 3.4 VDD1771 pKa = 3.75 GDD1773 pKa = 4.42 SNEE1776 pKa = 3.47 HH1777 pKa = 5.97 RR1778 pKa = 11.84 NYY1780 pKa = 9.64 IRR1782 pKa = 11.84 SVVDD1786 pKa = 3.76 FEE1788 pKa = 5.49 SNSRR1792 pKa = 11.84 PDD1794 pKa = 3.63 LNKK1797 pKa = 9.28 ATPKK1801 pKa = 9.08 VTEE1804 pKa = 4.17 AAQLCINPHH1813 pKa = 4.91 VKK1815 pKa = 10.43 CMLDD1819 pKa = 3.16 MFEE1822 pKa = 5.07 PFINNNTVGHH1832 pKa = 6.98 LALEE1836 pKa = 4.24 YY1837 pKa = 10.38 SNCEE1841 pKa = 4.08 IIQSWFGRR1849 pKa = 11.84 LEE1851 pKa = 4.4 SIVGKK1856 pKa = 9.14 EE1857 pKa = 3.89 WEE1859 pKa = 4.32 SQVAIMQLTTFSKK1872 pKa = 10.6 RR1873 pKa = 11.84 GFCFAYY1879 pKa = 10.24 GGGIYY1884 pKa = 9.34 TAMHH1888 pKa = 5.6 VTHH1891 pKa = 7.21 GDD1893 pKa = 3.85 SIFHH1897 pKa = 6.96 PGYY1900 pKa = 10.48 KK1901 pKa = 9.89 PLPCTFNSEE1910 pKa = 4.14 EE1911 pKa = 4.31 EE1912 pKa = 4.55 DD1913 pKa = 3.19 ICVYY1917 pKa = 10.92 GDD1919 pKa = 3.8 PLEE1922 pKa = 5.0 LEE1924 pKa = 4.14 QPKK1927 pKa = 9.88 TGDD1930 pKa = 2.85 LYY1932 pKa = 11.61 YY1933 pKa = 10.97 VVNPKK1938 pKa = 10.5 LGVYY1942 pKa = 9.49 VVLSLQKK1949 pKa = 9.78 EE1950 pKa = 4.08 QWGNKK1955 pKa = 5.85 YY1956 pKa = 9.27 YY1957 pKa = 10.75 RR1958 pKa = 11.84 RR1959 pKa = 11.84 IVSGDD1964 pKa = 3.45 YY1965 pKa = 10.64 KK1966 pKa = 10.87 VINYY1970 pKa = 9.52 ADD1972 pKa = 3.32 QRR1974 pKa = 11.84 GTLFRR1979 pKa = 11.84 NDD1981 pKa = 3.9 FDD1983 pKa = 6.0 DD1984 pKa = 5.17 EE1985 pKa = 4.49 PATQSLFSSDD1995 pKa = 3.26 SCNLHH2000 pKa = 5.93 GWSGLPICRR2009 pKa = 11.84 ISDD2012 pKa = 3.88 GKK2014 pKa = 10.0 PVGIYY2019 pKa = 9.86 TGTEE2023 pKa = 4.08 KK2024 pKa = 10.02 IDD2026 pKa = 3.3 GSIWIKK2032 pKa = 10.64 NVSPTKK2038 pKa = 10.46 IPAQPFNRR2046 pKa = 11.84 IINDD2050 pKa = 3.26 ILDD2053 pKa = 3.94 TPTVRR2058 pKa = 11.84 FTLDD2062 pKa = 2.91 APTGAGKK2069 pKa = 6.87 TTRR2072 pKa = 11.84 FVLQLAEE2079 pKa = 4.39 QSILKK2084 pKa = 9.65 NKK2086 pKa = 9.31 PIHH2089 pKa = 6.44 ILVANPLLTITYY2101 pKa = 8.46 AYY2103 pKa = 10.05 EE2104 pKa = 4.31 FVKK2107 pKa = 9.39 HH2108 pKa = 5.46 TLLEE2112 pKa = 4.35 KK2113 pKa = 10.76 SSLRR2117 pKa = 11.84 DD2118 pKa = 3.67 KK2119 pKa = 11.11 ISMNLQTSSVTKK2131 pKa = 11.12 YY2132 pKa = 7.05 EE2133 pKa = 4.25 TKK2135 pKa = 10.37 KK2136 pKa = 10.48 LASITYY2142 pKa = 6.51 MTYY2145 pKa = 10.87 GCVLNQMKK2153 pKa = 10.65 NNASLPYY2160 pKa = 10.26 DD2161 pKa = 3.02 IVLLDD2166 pKa = 4.1 EE2167 pKa = 4.58 CHH2169 pKa = 6.47 TDD2171 pKa = 3.35 QPHH2174 pKa = 4.73 VVAVLTAKK2182 pKa = 10.38 NLPRR2186 pKa = 11.84 HH2187 pKa = 5.54 VLMTATPLFGGLAPSYY2203 pKa = 10.22 RR2204 pKa = 11.84 SNIDD2208 pKa = 2.94 VRR2210 pKa = 11.84 KK2211 pKa = 8.38 ITHH2214 pKa = 6.94 KK2215 pKa = 10.09 STAAQGFVEE2224 pKa = 5.89 LYY2226 pKa = 9.46 TNTFVKK2232 pKa = 10.69 QEE2234 pKa = 3.97 VFEE2237 pKa = 4.84 DD2238 pKa = 3.65 LCKK2241 pKa = 10.13 PGSIIFCGSIAEE2253 pKa = 4.11 TDD2255 pKa = 3.35 KK2256 pKa = 11.37 VKK2258 pKa = 10.96 NRR2260 pKa = 11.84 IQKK2263 pKa = 9.67 QNAEE2267 pKa = 4.15 AQVVTVSSKK2276 pKa = 9.14 TPLRR2280 pKa = 11.84 EE2281 pKa = 3.82 VDD2283 pKa = 3.79 SSRR2286 pKa = 11.84 DD2287 pKa = 3.32 DD2288 pKa = 4.16 CVWVTTDD2295 pKa = 3.55 ALMSGVTIAKK2305 pKa = 9.29 AVRR2308 pKa = 11.84 GIAQGRR2314 pKa = 11.84 QFRR2317 pKa = 11.84 QTFSVVEE2324 pKa = 3.98 QRR2326 pKa = 11.84 AEE2328 pKa = 3.73 LMARR2332 pKa = 11.84 KK2333 pKa = 6.08 TTLSEE2338 pKa = 4.05 DD2339 pKa = 3.18 VQMAGRR2345 pKa = 11.84 IARR2348 pKa = 11.84 TPNSFGVWYY2357 pKa = 10.49 KK2358 pKa = 10.69 LDD2360 pKa = 3.76 EE2361 pKa = 4.71 YY2362 pKa = 10.7 YY2363 pKa = 10.6 HH2364 pKa = 6.1 EE2365 pKa = 5.35 PSWSPHH2371 pKa = 5.74 LLLSALTALNARR2383 pKa = 11.84 KK2384 pKa = 8.92 IQYY2387 pKa = 8.95 DD2388 pKa = 3.45 RR2389 pKa = 11.84 KK2390 pKa = 10.38 YY2391 pKa = 9.35 YY2392 pKa = 10.63 EE2393 pKa = 4.06 CVKK2396 pKa = 10.96 DD2397 pKa = 4.09 LVAGIADD2404 pKa = 4.61 DD2405 pKa = 5.02 DD2406 pKa = 4.4 EE2407 pKa = 5.48 LWVQADD2413 pKa = 3.8 KK2414 pKa = 11.74 NSIDD2418 pKa = 3.43 GVSFKK2423 pKa = 10.98 KK2424 pKa = 10.47 FLEE2427 pKa = 4.64 SGTIPYY2433 pKa = 10.19 HH2434 pKa = 6.87 FDD2436 pKa = 2.91 AKK2438 pKa = 10.99 LPGKK2442 pKa = 10.02 EE2443 pKa = 3.94 RR2444 pKa = 11.84 GTHH2447 pKa = 5.52 EE2448 pKa = 4.31 DD2449 pKa = 2.98 WFEE2452 pKa = 3.72 LSKK2455 pKa = 10.71 KK2456 pKa = 9.79 YY2457 pKa = 10.37 RR2458 pKa = 11.84 EE2459 pKa = 3.9 LSRR2462 pKa = 11.84 FDD2464 pKa = 4.06 EE2465 pKa = 4.62 NCAEE2469 pKa = 4.31 CGEE2472 pKa = 4.31 KK2473 pKa = 10.01 KK2474 pKa = 9.95 RR2475 pKa = 11.84 RR2476 pKa = 11.84 LRR2478 pKa = 11.84 RR2479 pKa = 11.84 DD2480 pKa = 3.34 HH2481 pKa = 7.02 EE2482 pKa = 4.12 EE2483 pKa = 3.92 HH2484 pKa = 6.79 AVGTIGLAVVAAGTTAGCLLAYY2506 pKa = 8.39 MCSHH2510 pKa = 5.58 QQVLVNDD2517 pKa = 3.75 VWWPQRR2523 pKa = 11.84 EE2524 pKa = 4.24 KK2525 pKa = 11.3 NFNGLLSGVTHH2536 pKa = 7.11 DD2537 pKa = 4.47 FVLGYY2542 pKa = 7.83 TEE2544 pKa = 5.43 KK2545 pKa = 10.75 EE2546 pKa = 3.89 LEE2548 pKa = 4.26 KK2549 pKa = 11.4 YY2550 pKa = 10.13 EE2551 pKa = 4.41 GFYY2554 pKa = 10.88 DD2555 pKa = 3.4 PHH2557 pKa = 7.73 YY2558 pKa = 10.66 KK2559 pKa = 9.5 ATFKK2563 pKa = 10.52 AWKK2566 pKa = 8.43 PDD2568 pKa = 3.16 RR2569 pKa = 11.84 SNDD2572 pKa = 3.24 EE2573 pKa = 3.56 GFIRR2577 pKa = 11.84 HH2578 pKa = 5.83 NLMIKK2583 pKa = 10.26 VPTSTNYY2590 pKa = 10.03 QMYY2593 pKa = 8.18 HH2594 pKa = 4.08 VKK2596 pKa = 10.18 YY2597 pKa = 9.54 RR2598 pKa = 11.84 NHH2600 pKa = 5.83 HH2601 pKa = 6.16 RR2602 pKa = 11.84 IARR2605 pKa = 11.84 NYY2607 pKa = 10.45 KK2608 pKa = 9.94 LDD2610 pKa = 3.64 EE2611 pKa = 4.77 HH2612 pKa = 7.38 PDD2614 pKa = 3.55 LDD2616 pKa = 3.83 WYY2618 pKa = 10.31 DD2619 pKa = 2.84 IRR2621 pKa = 11.84 NPVFSDD2627 pKa = 2.97 TDD2629 pKa = 3.07 GRR2631 pKa = 11.84 RR2632 pKa = 11.84 RR2633 pKa = 11.84 LMPDD2637 pKa = 2.94 EE2638 pKa = 5.41 LDD2640 pKa = 3.54 GFNPRR2645 pKa = 11.84 RR2646 pKa = 11.84 CVLEE2650 pKa = 3.3 QRR2652 pKa = 11.84 RR2653 pKa = 11.84 RR2654 pKa = 11.84 KK2655 pKa = 10.08 KK2656 pKa = 9.39 STLIKK2661 pKa = 10.84 GFIQQLIMLFGDD2673 pKa = 3.49 NTVTRR2678 pKa = 11.84 SIRR2681 pKa = 11.84 DD2682 pKa = 3.25 ALVPYY2687 pKa = 9.53 EE2688 pKa = 4.08 YY2689 pKa = 10.5 EE2690 pKa = 3.66 SDD2692 pKa = 3.03 RR2693 pKa = 11.84 MQRR2696 pKa = 11.84 HH2697 pKa = 6.77 AIFTYY2702 pKa = 9.91 VPFYY2706 pKa = 10.81 HH2707 pKa = 6.96 WFCIQTGTTPVLFMEE2722 pKa = 4.34 WLKK2725 pKa = 10.35 TYY2727 pKa = 10.65 GFAFLPAVMAPLGNEE2742 pKa = 3.47 IAGSVGSFILAIAATYY2758 pKa = 6.86 MTFYY2762 pKa = 10.54 TVGIKK2767 pKa = 10.04 ISYY2770 pKa = 9.78 DD2771 pKa = 3.17 VLAGVICANGFVTWLLNKK2789 pKa = 10.23 FGNASLKK2796 pKa = 10.79 KK2797 pKa = 10.19 NLLIDD2802 pKa = 3.84 TQAGLRR2808 pKa = 11.84 DD2809 pKa = 3.93 RR2810 pKa = 11.84 FTKK2813 pKa = 10.36 PFLISAVTMSAVVAYY2828 pKa = 10.12 QNGHH2832 pKa = 5.52 VGLPAVLTNLAEE2844 pKa = 4.27 EE2845 pKa = 4.0 ASKK2848 pKa = 10.77 RR2849 pKa = 11.84 IGLAPVTTTQSFVASVVEE2867 pKa = 3.95 GDD2869 pKa = 3.81 LVSFIYY2875 pKa = 10.41 RR2876 pKa = 11.84 CMRR2879 pKa = 11.84 FIDD2882 pKa = 3.85 EE2883 pKa = 5.03 GDD2885 pKa = 3.62 INSNWVAMCVDD2896 pKa = 3.7 VGITALNLPYY2906 pKa = 10.35 SQVAAAVVLAFLFYY2920 pKa = 10.72 LSKK2923 pKa = 11.03 KK2924 pKa = 9.84 NDD2926 pKa = 3.4 IIKK2929 pKa = 9.25 TVLIKK2934 pKa = 10.81 AQLLKK2939 pKa = 10.7 DD2940 pKa = 3.75 RR2941 pKa = 11.84 KK2942 pKa = 8.8 TSTEE2946 pKa = 3.75 DD2947 pKa = 2.84 AKK2949 pKa = 11.51 ASDD2952 pKa = 4.25 RR2953 pKa = 11.84 YY2954 pKa = 10.95 LLGEE2958 pKa = 5.31 DD2959 pKa = 3.21 IDD2961 pKa = 4.36 KK2962 pKa = 11.23 KK2963 pKa = 10.98 LVLDD2967 pKa = 4.25 AVCFLSYY2974 pKa = 10.45 CVNPLNMLKK2983 pKa = 10.6 AMSGFTVSYY2992 pKa = 9.89 IYY2994 pKa = 11.17 NKK2996 pKa = 6.82 VTRR2999 pKa = 11.84 RR3000 pKa = 11.84 DD3001 pKa = 3.57 FEE3003 pKa = 4.34 MKK3005 pKa = 10.65 DD3006 pKa = 3.5 LVLKK3010 pKa = 9.76 SLRR3013 pKa = 11.84 DD3014 pKa = 3.38 APMGVVYY3021 pKa = 9.19 MAKK3024 pKa = 9.73 QFYY3027 pKa = 10.18 CQITEE3032 pKa = 3.82 IANLILRR3039 pKa = 11.84 YY3040 pKa = 9.88 FGDD3043 pKa = 3.5 RR3044 pKa = 11.84 DD3045 pKa = 3.77 DD3046 pKa = 4.95 RR3047 pKa = 11.84 HH3048 pKa = 6.37 ASPDD3052 pKa = 3.46 NVLSGLYY3059 pKa = 9.5 EE3060 pKa = 4.04 LAVQKK3065 pKa = 10.89 CSGIPDD3071 pKa = 3.69 WFKK3074 pKa = 10.91 QSCSKK3079 pKa = 10.63 VKK3081 pKa = 10.53 QFICDD3086 pKa = 3.64 MVPGDD3091 pKa = 4.0 NVMLARR3097 pKa = 11.84 IRR3099 pKa = 11.84 IIFKK3103 pKa = 10.61 KK3104 pKa = 10.69 LFFKK3108 pKa = 10.67 PLLWVARR3115 pKa = 11.84 WFWSIAQKK3123 pKa = 10.89 IMGVCMLMSIPLIGASEE3140 pKa = 4.2 VLRR3143 pKa = 11.84 CILEE3147 pKa = 4.13 KK3148 pKa = 10.37 TFSFLGRR3155 pKa = 11.84 VNKK3158 pKa = 10.31 KK3159 pKa = 7.95 FTNLLYY3165 pKa = 10.75 GFTMSHH3171 pKa = 5.37 WEE3173 pKa = 3.85 YY3174 pKa = 10.48 NISIFASNEE3183 pKa = 3.77 QIRR3186 pKa = 11.84 TCMEE3190 pKa = 3.67 RR3191 pKa = 11.84 SKK3193 pKa = 10.29 MYY3195 pKa = 9.01 PHH3197 pKa = 7.16 WKK3199 pKa = 10.16 LEE3201 pKa = 3.87 RR3202 pKa = 11.84 LLAGLAEE3209 pKa = 4.62 PEE3211 pKa = 4.11 TEE3213 pKa = 4.04 RR3214 pKa = 11.84 RR3215 pKa = 11.84 RR3216 pKa = 11.84 SSTPNSSVDD3225 pKa = 3.22 EE3226 pKa = 3.93 QLNYY3230 pKa = 10.26 LEE3232 pKa = 4.77 RR3233 pKa = 11.84 MARR3236 pKa = 11.84 EE3237 pKa = 4.16 DD3238 pKa = 4.38 PEE3240 pKa = 4.2 VSMIGVNLEE3249 pKa = 4.16 CSGGGYY3255 pKa = 9.46 IDD3257 pKa = 4.89 DD3258 pKa = 5.79 SIRR3261 pKa = 11.84 QMSPEE3266 pKa = 3.79 RR3267 pKa = 11.84 LEE3269 pKa = 4.19 EE3270 pKa = 3.69 QDD3272 pKa = 3.16 RR3273 pKa = 11.84 QYY3275 pKa = 11.83 AEE3277 pKa = 4.34 AMGPNLGDD3285 pKa = 3.49 NCEE3288 pKa = 4.23 LEE3290 pKa = 4.42 ALSSEE3295 pKa = 4.25 RR3296 pKa = 11.84 VQHH3299 pKa = 5.92 CEE3301 pKa = 3.52 KK3302 pKa = 10.68 FSLLRR3307 pKa = 11.84 TLFDD3311 pKa = 3.77 MMIEE3315 pKa = 4.26 PPSEE3319 pKa = 4.17 DD3320 pKa = 3.18 MSPTANIYY3328 pKa = 9.15 VNKK3331 pKa = 9.59 PIEE3334 pKa = 3.83 WLQNVVEE3341 pKa = 4.43 VADD3344 pKa = 3.77 VDD3346 pKa = 3.88 QKK3348 pKa = 9.69 TKK3350 pKa = 10.66 RR3351 pKa = 11.84 EE3352 pKa = 4.14 SNIPYY3357 pKa = 9.63 YY3358 pKa = 10.31 SAYY3361 pKa = 10.2 LSGMNPHH3368 pKa = 6.73 PVDD3371 pKa = 3.68 PLEE3374 pKa = 4.23 EE3375 pKa = 4.17 KK3376 pKa = 8.74 TLKK3379 pKa = 8.23 MTEE3382 pKa = 3.89 DD3383 pKa = 4.25 TIWPDD3388 pKa = 3.27 LYY3390 pKa = 10.86 GAEE3393 pKa = 4.58 VIGNTQIAFEE3403 pKa = 4.15 KK3404 pKa = 10.42 LKK3406 pKa = 10.26 TILTVNVKK3414 pKa = 8.16 QKK3416 pKa = 10.52 RR3417 pKa = 11.84 SGRR3420 pKa = 11.84 EE3421 pKa = 3.76 ALPEE3425 pKa = 4.09 SASQVTSRR3433 pKa = 11.84 GFYY3436 pKa = 10.94 VMSNLDD3442 pKa = 3.44 KK3443 pKa = 10.89 NDD3445 pKa = 3.32 SVFRR3449 pKa = 11.84 DD3450 pKa = 3.2 WDD3452 pKa = 4.03 LKK3454 pKa = 10.32 TMSSKK3459 pKa = 10.61 IKK3461 pKa = 10.03 DD3462 pKa = 3.33 KK3463 pKa = 11.65 SMTVLDD3469 pKa = 3.98 ATPGFGGSVNYY3480 pKa = 10.22 LLQSMKK3486 pKa = 10.61 GGSLHH3491 pKa = 7.26 IYY3493 pKa = 9.47 QRR3495 pKa = 11.84 QKK3497 pKa = 11.39 DD3498 pKa = 3.91 PWPLKK3503 pKa = 10.44 EE3504 pKa = 6.06 DD3505 pKa = 5.17 LITPNINVKK3514 pKa = 9.83 VIRR3517 pKa = 11.84 SDD3519 pKa = 3.27 QFCYY3523 pKa = 10.41 KK3524 pKa = 10.44 EE3525 pKa = 4.04 EE3526 pKa = 3.93 EE3527 pKa = 4.13 FDD3529 pKa = 5.28 FVVCDD3534 pKa = 3.65 SVSDD3538 pKa = 3.43 IKK3540 pKa = 11.33 SIVSRR3545 pKa = 11.84 NDD3547 pKa = 2.96 KK3548 pKa = 10.92 EE3549 pKa = 5.57 FVLQCHH3555 pKa = 4.94 NVVRR3559 pKa = 11.84 QGGSFWVSCGLLDD3572 pKa = 4.38 ILNWPQEE3579 pKa = 4.28 LNCYY3583 pKa = 7.92 EE3584 pKa = 4.07 HH3585 pKa = 7.33 AKK3587 pKa = 10.28 FHH3589 pKa = 7.3 ISPTPNADD3597 pKa = 3.34 KK3598 pKa = 10.68 FYY3600 pKa = 10.68 FWVQLGGRR3608 pKa = 11.84 TTTRR3612 pKa = 11.84 KK3613 pKa = 9.31 IYY3615 pKa = 9.95 VNRR3618 pKa = 11.84 FYY3620 pKa = 11.33 GILCDD3625 pKa = 3.88 LVRR3628 pKa = 11.84 IHH3630 pKa = 7.12 LLKK3633 pKa = 10.8 LKK3635 pKa = 10.69 YY3636 pKa = 9.82 AVKK3639 pKa = 10.16 KK3640 pKa = 10.41 DD3641 pKa = 3.53 KK3642 pKa = 11.26 KK3643 pKa = 10.0 PVQLYY3648 pKa = 10.49 HH3649 pKa = 7.14 PVIQKK3654 pKa = 10.31 NKK3656 pKa = 8.17 TGAIPMINYY3665 pKa = 6.98 TQNIDD3670 pKa = 3.29 RR3671 pKa = 11.84 DD3672 pKa = 3.9 RR3673 pKa = 11.84 YY3674 pKa = 10.2 SEE3676 pKa = 4.11 MFEE3679 pKa = 4.11 MTNTSYY3685 pKa = 11.12 KK3686 pKa = 9.59 IRR3688 pKa = 11.84 HH3689 pKa = 5.89 RR3690 pKa = 11.84 LDD3692 pKa = 3.84 RR3693 pKa = 11.84 LDD3695 pKa = 4.04 SMRR3698 pKa = 11.84 KK3699 pKa = 7.75 QPRR3702 pKa = 11.84 LMKK3705 pKa = 10.5 SFSRR3709 pKa = 11.84 LQNFQFLTSVDD3720 pKa = 3.87 FKK3722 pKa = 11.14 RR3723 pKa = 11.84 GVRR3726 pKa = 11.84 LLPGKK3731 pKa = 9.92 LRR3733 pKa = 11.84 NQLIVATWDD3742 pKa = 3.24 QEE3744 pKa = 4.49 RR3745 pKa = 11.84 VKK3747 pKa = 10.07 VTSDD3751 pKa = 2.87 RR3752 pKa = 11.84 VLVSNVLSDD3761 pKa = 3.5 MLHH3764 pKa = 7.69 DD3765 pKa = 3.83 IFAVNWANTPITQVSKK3781 pKa = 10.95 DD3782 pKa = 3.46 LHH3784 pKa = 6.69 KK3785 pKa = 11.09 VDD3787 pKa = 3.54 MAIVDD3792 pKa = 3.99 RR3793 pKa = 11.84 LDD3795 pKa = 3.47 INNKK3799 pKa = 9.2 VLLDD3803 pKa = 3.79 SQVEE3807 pKa = 4.26 KK3808 pKa = 10.85 LLEE3811 pKa = 4.09 ASEE3814 pKa = 5.71 FILQPPDD3821 pKa = 3.54 RR3822 pKa = 11.84 LFKK3825 pKa = 10.72 LCTWEE3830 pKa = 4.07 EE3831 pKa = 3.94 LGTFINRR3838 pKa = 11.84 QGAAGMLDD3846 pKa = 4.06 DD3847 pKa = 4.02 VSKK3850 pKa = 10.58 MGEE3853 pKa = 4.19 LYY3855 pKa = 10.71 DD3856 pKa = 4.71 DD3857 pKa = 3.38 SRR3859 pKa = 11.84 TRR3861 pKa = 11.84 KK3862 pKa = 9.82 LCEE3865 pKa = 3.83 QIIGCLANGQDD3876 pKa = 3.59 CPLYY3880 pKa = 11.0 YY3881 pKa = 9.56 STCHH3885 pKa = 6.12 HH3886 pKa = 6.24 KK3887 pKa = 10.94 VEE3889 pKa = 4.7 SKK3891 pKa = 9.4 VSKK3894 pKa = 10.18 RR3895 pKa = 11.84 AVDD3898 pKa = 3.69 GKK3900 pKa = 10.72 IVDD3903 pKa = 4.05 TLPALLKK3910 pKa = 9.87 PVPRR3914 pKa = 11.84 LIQYY3918 pKa = 9.01 LSSYY3922 pKa = 10.14 ARR3924 pKa = 11.84 LVDD3927 pKa = 3.12 IWIFGSMMHH3936 pKa = 5.94 YY3937 pKa = 10.33 HH3938 pKa = 5.98 MKK3940 pKa = 10.18 VKK3942 pKa = 10.42 KK3943 pKa = 10.0 LYY3945 pKa = 9.96 KK3946 pKa = 9.99 YY3947 pKa = 10.67 SNTGTPITHH3956 pKa = 6.6 VGDD3959 pKa = 4.06 DD3960 pKa = 3.56 MHH3962 pKa = 7.09 AAWEE3966 pKa = 4.14 KK3967 pKa = 10.88 HH3968 pKa = 6.03 GGDD3971 pKa = 4.28 DD3972 pKa = 3.45 EE3973 pKa = 5.5 CIGVTGDD3980 pKa = 3.76 ASRR3983 pKa = 11.84 WDD3985 pKa = 3.8 HH3986 pKa = 6.37 NLGPSHH3992 pKa = 6.81 TYY3994 pKa = 9.7 VEE3996 pKa = 4.5 KK3997 pKa = 10.77 EE3998 pKa = 4.02 CVKK4001 pKa = 10.76 KK4002 pKa = 10.65 FFEE4005 pKa = 4.59 PSMHH4009 pKa = 6.8 KK4010 pKa = 10.07 IIEE4013 pKa = 4.05 TRR4015 pKa = 11.84 YY4016 pKa = 8.19 EE4017 pKa = 3.84 HH4018 pKa = 6.08 TAFPITFTDD4027 pKa = 2.67 MGYY4030 pKa = 10.75 AVSTAGQRR4038 pKa = 11.84 QSGDD4042 pKa = 3.5 YY4043 pKa = 8.67 LTSWGNGLIHH4053 pKa = 6.98 SLIQHH4058 pKa = 5.28 VCWSKK4063 pKa = 9.57 VLHH4066 pKa = 5.8 RR4067 pKa = 11.84 GVRR4070 pKa = 11.84 EE4071 pKa = 3.89 SHH4073 pKa = 6.55 EE4074 pKa = 4.31 DD4075 pKa = 3.6 LVEE4078 pKa = 3.99 HH4079 pKa = 6.87 RR4080 pKa = 11.84 VDD4082 pKa = 5.83 GDD4084 pKa = 4.56 DD4085 pKa = 3.45 NWHH4088 pKa = 5.87 MMNFRR4093 pKa = 11.84 HH4094 pKa = 5.88 ICVGRR4099 pKa = 11.84 EE4100 pKa = 3.37 KK4101 pKa = 11.31 DD4102 pKa = 4.21 KK4103 pKa = 11.23 FDD4105 pKa = 3.86 EE4106 pKa = 5.07 KK4107 pKa = 11.32 AKK4109 pKa = 10.3 LWEE4112 pKa = 4.62 KK4113 pKa = 10.37 IKK4115 pKa = 11.01 RR4116 pKa = 11.84 PGNLFDD4122 pKa = 5.48 KK4123 pKa = 10.64 EE4124 pKa = 4.14 PALSAEE4130 pKa = 3.89 ISFDD4134 pKa = 3.95 NILTRR4139 pKa = 11.84 VARR4142 pKa = 11.84 HH4143 pKa = 4.81 YY4144 pKa = 11.31 EE4145 pKa = 3.88 EE4146 pKa = 5.76 FGVKK4150 pKa = 9.59 LRR4152 pKa = 11.84 SGTHH4156 pKa = 4.57 TGFRR4160 pKa = 11.84 LHH4162 pKa = 6.0 YY4163 pKa = 9.88 QFSTVDD4169 pKa = 4.27 FLSHH4173 pKa = 7.09 TYY4175 pKa = 9.46 TEE4177 pKa = 4.11 IPIRR4181 pKa = 11.84 CIKK4184 pKa = 10.18 DD4185 pKa = 3.16 GNYY4188 pKa = 9.29 VQVRR4192 pKa = 11.84 KK4193 pKa = 9.55 YY4194 pKa = 11.01 LPVRR4198 pKa = 11.84 PYY4200 pKa = 11.13 SEE4202 pKa = 4.27 MFGKK4206 pKa = 10.74 LLFTLKK4212 pKa = 10.44 QGTSKK4217 pKa = 11.14 YY4218 pKa = 9.45 YY4219 pKa = 9.72 GAAIYY4224 pKa = 9.97 DD4225 pKa = 3.59 HH4226 pKa = 6.75 SRR4228 pKa = 11.84 GRR4230 pKa = 11.84 EE4231 pKa = 3.69 IAKK4234 pKa = 9.65 DD4235 pKa = 3.11 ACEE4238 pKa = 4.88 AIDD4241 pKa = 3.75 IQTSKK4246 pKa = 10.89 CMSYY4250 pKa = 10.68 LFQYY4254 pKa = 8.62 PHH4256 pKa = 6.3 VMCIRR4261 pKa = 11.84 EE4262 pKa = 3.91 FCLGVLSYY4270 pKa = 11.26 LGGPPSDD4277 pKa = 3.46 VKK4279 pKa = 10.96 KK4280 pKa = 9.67 WGSQFRR4286 pKa = 11.84 VTEE4289 pKa = 3.81 RR4290 pKa = 11.84 LAIDD4294 pKa = 3.53 KK4295 pKa = 10.62 VLAKK4299 pKa = 10.25 LDD4301 pKa = 3.65 EE4302 pKa = 4.4 VKK4304 pKa = 10.77 RR4305 pKa = 11.84 LDD4307 pKa = 3.6 WTCVEE4312 pKa = 3.93 PALRR4316 pKa = 11.84 QILDD4320 pKa = 3.73 LDD4322 pKa = 3.65 ITSLSDD4328 pKa = 2.66 IGTVSFEE4335 pKa = 4.16 QDD4337 pKa = 3.37 NFWKK4341 pKa = 9.87 EE4342 pKa = 3.56 QHH4344 pKa = 6.47 AEE4346 pKa = 3.89 NVALCARR4353 pKa = 11.84 EE4354 pKa = 4.04 YY4355 pKa = 10.73 KK4356 pKa = 10.16 IEE4358 pKa = 4.04 APRR4361 pKa = 11.84 FVHH4364 pKa = 6.3 SGDD4367 pKa = 3.44 YY4368 pKa = 9.59 MRR4370 pKa = 11.84 STRR4373 pKa = 11.84 IRR4375 pKa = 11.84 EE4376 pKa = 4.17 RR4377 pKa = 11.84 IVKK4380 pKa = 8.51 TVLHH4384 pKa = 5.76 QYY4386 pKa = 9.41 RR4387 pKa = 11.84 MCMARR4392 pKa = 11.84 KK4393 pKa = 8.54 GVTMRR4398 pKa = 11.84 EE4399 pKa = 3.93 QIAINPVIIPFWGYY4413 pKa = 11.1 LSMSPRR4419 pKa = 11.84 LLSVAKK4425 pKa = 10.34 IKK4427 pKa = 10.65 VKK4429 pKa = 10.55 KK4430 pKa = 9.8 QLSEE4434 pKa = 4.19 YY4435 pKa = 10.35 GVEE4438 pKa = 4.36 LEE4440 pKa = 4.86 PEE4442 pKa = 3.73 ILDD4445 pKa = 3.59 RR4446 pKa = 11.84 LVEE4449 pKa = 4.21 GVEE4452 pKa = 4.1 PKK4454 pKa = 10.54 KK4455 pKa = 9.66 QTEE4458 pKa = 4.16 SNEE4461 pKa = 3.87 RR4462 pKa = 11.84 MKK4464 pKa = 11.13 SFIEE4468 pKa = 3.92 QTGLFSVTSVAALRR4482 pKa = 11.84 QAGKK4486 pKa = 8.72 YY4487 pKa = 5.93 TVKK4490 pKa = 10.14 TGDD4493 pKa = 3.35 HH4494 pKa = 5.99 TVTFSNVYY4502 pKa = 10.33 NDD4504 pKa = 3.54 AFGSGFQILSLRR4516 pKa = 11.84 KK4517 pKa = 9.96 LFGIPINCAAEE4528 pKa = 4.3 TVEE4531 pKa = 5.45 DD4532 pKa = 3.8 LQFTKK4537 pKa = 10.52 RR4538 pKa = 11.84 FLEE4541 pKa = 4.18 AQPAVRR4547 pKa = 11.84 VADD4550 pKa = 3.79 GFEE4553 pKa = 3.98 FQSMYY4558 pKa = 10.99 EE4559 pKa = 4.11 EE4560 pKa = 4.27 TRR4562 pKa = 11.84 PRR4564 pKa = 11.84 PDD4566 pKa = 2.59 KK4567 pKa = 9.18 TTTFEE4572 pKa = 3.98 IEE4574 pKa = 4.16 TVKK4577 pKa = 11.09 NILFKK4582 pKa = 10.64 RR4583 pKa = 11.84 YY4584 pKa = 9.27 GLSRR4588 pKa = 11.84 CEE4590 pKa = 3.75 TVFILNQLEE4599 pKa = 4.32 PAVLQHH4605 pKa = 6.25 NRR4607 pKa = 11.84 GKK4609 pKa = 10.75 VYY4611 pKa = 10.56 LRR4613 pKa = 11.84 SDD4615 pKa = 3.27 VGDD4618 pKa = 3.44 EE4619 pKa = 3.98 EE4620 pKa = 3.99 NFYY4623 pKa = 10.87 RR4624 pKa = 11.84 FKK4626 pKa = 10.97 LCYY4629 pKa = 9.41 IDD4631 pKa = 3.53 CTKK4634 pKa = 10.71 IKK4636 pKa = 10.25 LKK4638 pKa = 10.35 RR4639 pKa = 11.84 AGVFMRR4645 pKa = 11.84 SVVEE4649 pKa = 4.96 RR4650 pKa = 11.84 EE4651 pKa = 4.04 DD4652 pKa = 3.44 LSKK4655 pKa = 10.86 LVEE4658 pKa = 4.31 RR4659 pKa = 11.84 VGTLPVGSSCVVKK4672 pKa = 10.5 VDD4674 pKa = 3.19 KK4675 pKa = 10.81 TFLHH4679 pKa = 6.78 AVTIDD4684 pKa = 3.88 LDD4686 pKa = 3.98 SLSEE4690 pKa = 4.04 LFSVQEE4696 pKa = 3.96 IFRR4699 pKa = 11.84 SPFTGGSSEE4708 pKa = 4.18 LYY4710 pKa = 10.0 IYY4712 pKa = 10.73 FGGKK4716 pKa = 9.51 GLQQEE4721 pKa = 4.77 VKK4723 pKa = 9.86 VSRR4726 pKa = 11.84 IGNVEE4731 pKa = 3.88 AASCVPLRR4739 pKa = 11.84 EE4740 pKa = 3.85 QVAIFLKK4747 pKa = 11.03 LLLQSNHH4754 pKa = 6.42 LNMNKK4759 pKa = 9.63 NLASAVYY4766 pKa = 9.7 SGTSAFSDD4774 pKa = 3.33 EE4775 pKa = 4.56 HH4776 pKa = 7.73 VGILARR4782 pKa = 11.84 EE4783 pKa = 3.83 NAMIPFCTKK4792 pKa = 10.04 KK4793 pKa = 10.74 KK4794 pKa = 9.85 FDD4796 pKa = 4.12 LRR4798 pKa = 11.84 VKK4800 pKa = 10.24 QYY4802 pKa = 10.59 EE4803 pKa = 3.7 PGMRR4807 pKa = 11.84 FGVQGPLAIWQYY4819 pKa = 10.34 FVHH4822 pKa = 7.12 PSLVHH4827 pKa = 5.55 WFYY4830 pKa = 11.44 NAYY4833 pKa = 9.27 EE4834 pKa = 4.09 NEE4836 pKa = 4.13 MDD4838 pKa = 4.04 GKK4840 pKa = 10.57 RR4841 pKa = 11.84 RR4842 pKa = 11.84 DD4843 pKa = 3.73 VKK4845 pKa = 11.26 VMSSVPRR4852 pKa = 11.84 LLVPPSFKK4860 pKa = 10.57 LGKK4863 pKa = 10.23 LKK4865 pKa = 10.49 IEE4867 pKa = 4.42 FEE4869 pKa = 4.19 TDD4871 pKa = 2.59 LGKK4874 pKa = 10.8 EE4875 pKa = 4.01 DD4876 pKa = 4.33 FVRR4879 pKa = 11.84 DD4880 pKa = 3.89 SDD4882 pKa = 4.55 TNWLRR4887 pKa = 11.84 DD4888 pKa = 3.51 YY4889 pKa = 11.18 VIAKK4893 pKa = 9.06 TEE4895 pKa = 4.36 DD4896 pKa = 3.21 STLDD4900 pKa = 3.4 PKK4902 pKa = 10.6 HH4903 pKa = 6.45 ARR4905 pKa = 11.84 FRR4907 pKa = 11.84 NPVKK4911 pKa = 10.4 KK4912 pKa = 9.49 WIKK4915 pKa = 10.7 LDD4917 pKa = 3.46 VDD4919 pKa = 4.57 DD4920 pKa = 4.54 NTEE4923 pKa = 4.11 KK4924 pKa = 10.84 PSVAQFSYY4932 pKa = 8.0 QTCIRR4937 pKa = 11.84 ICQIISDD4944 pKa = 4.1 IGSKK4948 pKa = 10.8 NIVCEE4953 pKa = 4.29 IDD4955 pKa = 3.47 PDD4957 pKa = 4.0 DD4958 pKa = 5.29 DD4959 pKa = 4.31 GRR4961 pKa = 11.84 FTYY4964 pKa = 9.96 VFNYY4968 pKa = 7.64 LQCGKK4973 pKa = 9.47 VHH4975 pKa = 6.64 VDD4977 pKa = 3.19 RR4978 pKa = 11.84 EE4979 pKa = 4.35 KK4980 pKa = 11.06 PLLQALRR4987 pKa = 11.84 KK4988 pKa = 9.22 VGEE4991 pKa = 4.11 RR4992 pKa = 11.84 MSLRR4996 pKa = 11.84 EE4997 pKa = 3.65 THH4999 pKa = 6.58 EE5000 pKa = 4.17 PANLCVTRR5008 pKa = 11.84 NLSKK5012 pKa = 10.9 SYY5014 pKa = 10.12 DD5015 pKa = 3.48 RR5016 pKa = 11.84 KK5017 pKa = 10.68 YY5018 pKa = 10.73 VICVGNTSKK5027 pKa = 10.9 LDD5029 pKa = 3.53 EE5030 pKa = 4.01 VRR5032 pKa = 11.84 RR5033 pKa = 11.84 RR5034 pKa = 11.84 ARR5036 pKa = 11.84 HH5037 pKa = 4.61 VYY5039 pKa = 8.5 TRR5041 pKa = 11.84 FVEE5044 pKa = 4.52 TPILNEE5050 pKa = 3.88 QILLVSFRR5058 pKa = 11.84 EE5059 pKa = 3.99 VNITKK5064 pKa = 10.36 KK5065 pKa = 10.77 KK5066 pKa = 9.68 NLPPMRR5072 pKa = 11.84 SNRR5075 pKa = 11.84 IEE5077 pKa = 4.17 PLDD5080 pKa = 3.42 VNYY5083 pKa = 10.69 SVKK5086 pKa = 10.49 RR5087 pKa = 11.84 CVSYY5091 pKa = 10.29 DD5092 pKa = 2.95 HH5093 pKa = 6.7 RR5094 pKa = 11.84 QIDD5097 pKa = 3.45 ISKK5100 pKa = 10.21 KK5101 pKa = 9.47 KK5102 pKa = 10.25 LHH5104 pKa = 5.06 THH5106 pKa = 6.0 ICISCQTEE5114 pKa = 3.94 YY5115 pKa = 11.6 ASFHH5119 pKa = 7.19 DD5120 pKa = 3.78 ITRR5123 pKa = 11.84 QNHH5126 pKa = 5.12 GKK5128 pKa = 9.39 LCYY5131 pKa = 8.69 MCALQVYY5138 pKa = 8.31 IQRR5141 pKa = 11.84 EE5142 pKa = 4.18 KK5143 pKa = 10.37 EE5144 pKa = 4.24 AKK5146 pKa = 9.81 FQLNLDD5152 pKa = 3.54 RR5153 pKa = 11.84 HH5154 pKa = 6.29 DD5155 pKa = 4.5 NPVTDD5160 pKa = 4.13 HH5161 pKa = 6.72 FFDD5164 pKa = 4.4 VIAGAVRR5171 pKa = 11.84 EE5172 pKa = 4.03 YY5173 pKa = 11.26 LNEE5176 pKa = 3.99 LFNRR5180 pKa = 11.84 ALIMPMYY5187 pKa = 7.14 EE5188 pKa = 3.47 TWVWRR5193 pKa = 11.84 FTYY5196 pKa = 10.31 SRR5198 pKa = 11.84 AFAAPLIKK5206 pKa = 10.38 KK5207 pKa = 9.51 ILSPLLGFVFLMLMTGCGRR5226 pKa = 11.84 IGFGLLLVTMWLMAQFVPIVYY5247 pKa = 9.45 KK5248 pKa = 10.48 ISYY5251 pKa = 9.13 AEE5253 pKa = 3.89 VVMGVAGYY5261 pKa = 10.75 RR5262 pKa = 11.84 MPAEE5266 pKa = 4.13 STYY5269 pKa = 11.41 LLAFIFGLSFMTYY5282 pKa = 9.97 SAFDD5286 pKa = 3.64 LVKK5289 pKa = 10.67 LVLHH5293 pKa = 6.47 PFYY5296 pKa = 11.06 YY5297 pKa = 10.55 LWPSNWVDD5305 pKa = 2.92 ILSIVIFNPGVRR5317 pKa = 11.84 RR5318 pKa = 11.84 TDD5320 pKa = 3.02 RR5321 pKa = 11.84 YY5322 pKa = 9.97 IWNLCTLPIRR5332 pKa = 11.84 ITFDD5336 pKa = 2.74 TLYY5339 pKa = 10.85 YY5340 pKa = 9.03 LTKK5343 pKa = 10.72 SLLTYY5348 pKa = 10.46 LISFEE5353 pKa = 5.5 KK5354 pKa = 9.6 GRR5356 pKa = 11.84 QWATEE5361 pKa = 3.2 ISLRR5365 pKa = 11.84 HH5366 pKa = 4.56 ARR5368 pKa = 11.84 FRR5370 pKa = 11.84 EE5371 pKa = 3.86 FAQDD5375 pKa = 3.47 CFGPAARR5382 pKa = 11.84 RR5383 pKa = 11.84 AYY5385 pKa = 10.38 GIRR5388 pKa = 11.84 NYY5390 pKa = 10.78 YY5391 pKa = 10.43 NNLTRR5396 pKa = 11.84 DD5397 pKa = 3.61 FEE5399 pKa = 4.68 GANTASFYY5407 pKa = 10.78 FFYY5410 pKa = 11.13 YY5411 pKa = 10.47 FLNHH5415 pKa = 6.59 DD5416 pKa = 3.68 QVIVKK5421 pKa = 9.6 LYY5423 pKa = 8.58 VAVFFVLYY5431 pKa = 10.7 AHH5433 pKa = 6.43 FTGRR5437 pKa = 11.84 FNKK5440 pKa = 9.68 YY5441 pKa = 7.08 VQILRR5446 pKa = 11.84 LYY5448 pKa = 10.14 IIYY5451 pKa = 8.25 STHH5454 pKa = 6.72 WLNLWQDD5461 pKa = 3.4 PSQIVFNSLKK5471 pKa = 11.0 SNMLLEE5477 pKa = 4.26 LFGMGSDD5484 pKa = 3.51 SLGGISVKK5492 pKa = 9.94 TIPSFSTSTDD5502 pKa = 3.14 LKK5504 pKa = 10.96 LAACLILILLFVTLVDD5520 pKa = 4.93 FYY5522 pKa = 11.19 ISFYY5526 pKa = 10.45 QALAGTNALGPFCQYY5541 pKa = 10.82 VEE5543 pKa = 4.44 ALPEE5547 pKa = 3.85 FLNYY5551 pKa = 10.07 HH5552 pKa = 6.39 YY5553 pKa = 10.64 YY5554 pKa = 8.42 QTLEE5558 pKa = 3.71 YY5559 pKa = 10.29 LKK5561 pKa = 10.7 FIFYY5565 pKa = 10.24 FLVGCTIITLRR5576 pKa = 11.84 IIFRR5580 pKa = 11.84 NQFTEE5585 pKa = 3.92 ALFNRR5590 pKa = 11.84 AALHH5594 pKa = 6.77 ISAQYY5599 pKa = 9.9 RR5600 pKa = 11.84 NHH5602 pKa = 6.8 ISRR5605 pKa = 11.84 LIYY5608 pKa = 9.92 PYY5610 pKa = 10.83 VAVLGNILHH5619 pKa = 5.92 QFGIIDD5625 pKa = 3.7 FTGLANLQIILFAFHH5640 pKa = 6.91 WAGVGYY5646 pKa = 10.13 ISDD5649 pKa = 4.19 DD5650 pKa = 3.93 ADD5652 pKa = 3.72 PTIHH5656 pKa = 6.95 WSITLVMCLFKK5667 pKa = 11.05 LIGFSPYY5674 pKa = 8.37 VTLVLVLIIFGPVIHH5689 pKa = 6.69 FFGFEE5694 pKa = 4.67 LIRR5697 pKa = 11.84 YY5698 pKa = 8.72 LSLQTAIRR5706 pKa = 11.84 GMFNLCRR5713 pKa = 11.84 NTFIHH5718 pKa = 6.97 NILFVCVISNLTGTIHH5734 pKa = 6.42 PVVTVGVIILLKK5746 pKa = 10.43 HH5747 pKa = 4.33 LTEE5750 pKa = 5.09 RR5751 pKa = 11.84 YY5752 pKa = 10.05 SFLLPSRR5759 pKa = 11.84 RR5760 pKa = 11.84 TVANLFVLDD5769 pKa = 3.74 SFLFVLMYY5777 pKa = 8.19 NTWAFFDD5784 pKa = 3.9 LQPTFVLEE5792 pKa = 4.28 YY5793 pKa = 8.84 IWRR5796 pKa = 11.84 FLFQFYY5802 pKa = 10.15 IGQPPGSS5809 pKa = 3.66
Molecular weight: 665.05 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 6.792
IPC2_protein 7.102
IPC_protein 6.898
Toseland 6.722
ProMoST 7.512
Dawson 7.571
Bjellqvist 8.039
Wikipedia 7.483
Rodwell 7.585
Grimsley 6.795
Solomon 7.571
Lehninger 7.585
Nozaki 8.244
DTASelect 7.775
Thurlkill 7.819
EMBOSS 7.805
Sillero 8.126
Patrickios 4.062
IPC_peptide 7.571
IPC2_peptide 7.234
IPC2.peptide.svr19 7.066
Peptides (in silico digests for buttom-up proteomics)
Below you can find
in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.
Try ESI
ChTry ESI
ArgC ESI
LysN ESI
TryLysC ESI
Try MALDI
ChTry MALDI
ArgC MALDI
LysN MALDI
TryLysC MALDI
Try LTQ
ChTry LTQ
ArgC LTQ
LysN LTQ
TryLysC LTQ
Try MSlow
ChTry MSlow
ArgC MSlow
LysN MSlow
TryLysC MSlow
Try MShigh
ChTry MShigh
ArgC MShigh
LysN MShigh
TryLysC MShigh
General Statistics
Number of major isoforms
Number of additional isoforms
Number of all proteins
Number of amino acids
Min. Seq. Length
Max. Seq. Length
Avg. Seq. Length
Avg. Mol. Weight
1
0
1
5809
5809
5809
5809.0
665.05
Amino acid frequency
Ala
Cys
Asp
Glu
Phe
Gly
His
Ile
Lys
Leu
5.646 ± 0.0
2.617 ± 0.0
5.543 ± 0.0
6.128 ± 0.0
5.147 ± 0.0
5.491 ± 0.0
2.393 ± 0.0
6.111 ± 0.0
6.146 ± 0.0
9.107 ± 0.0
Met
Asn
Gln
Pro
Arg
Ser
Thr
Val
Trp
Tyr
2.203 ± 0.0
4.132 ± 0.0
3.581 ± 0.0
3.34 ± 0.0
5.887 ± 0.0
6.783 ± 0.0
5.732 ± 0.0
7.953 ± 0.0
1.567 ± 0.0
4.493 ± 0.0
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level
Most of the basic statistics you can see at this page can be downloaded from this CSV file
For dipeptide frequency statistics click here