Amino acid dipepetide frequency for Mandrillus leucophaeus (Drill) (Papio leucophaeus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.212AlaAla: 6.212 ± 0.034	1.366AlaCys: 1.366 ± 0.009	2.88AlaAsp: 2.88 ± 0.012	4.688AlaGlu: 4.688 ± 0.025	2.597AlaPhe: 2.597 ± 0.015	4.481AlaGly: 4.481 ± 0.024	1.528AlaHis: 1.528 ± 0.01	2.823AlaIle: 2.823 ± 0.015	3.509AlaLys: 3.509 ± 0.019	6.927AlaLeu: 6.927 ± 0.031	1.481AlaMet: 1.481 ± 0.01	2.047AlaAsn: 2.047 ± 0.011	3.9AlaPro: 3.9 ± 0.022	3.205AlaGln: 3.205 ± 0.018	3.459AlaArg: 3.459 ± 0.017	5.626AlaSer: 5.626 ± 0.022	3.604AlaThr: 3.604 ± 0.015	4.654AlaVal: 4.654 ± 0.017	0.798AlaTrp: 0.798 ± 0.008	1.53AlaTyr: 1.53 ± 0.009	0.0AlaXaa: 0.0 ± 0.0
Cys	1.205CysAla: 1.205 ± 0.01	0.646CysCys: 0.646 ± 0.01	1.021CysAsp: 1.021 ± 0.011	1.318CysGlu: 1.318 ± 0.013	0.845CysPhe: 0.845 ± 0.008	1.726CysGly: 1.726 ± 0.016	0.677CysHis: 0.677 ± 0.007	0.977CysIle: 0.977 ± 0.009	1.193CysLys: 1.193 ± 0.009	2.203CysLeu: 2.203 ± 0.014	0.421CysMet: 0.421 ± 0.005	0.838CysAsn: 0.838 ± 0.009	1.368CysPro: 1.368 ± 0.013	1.088CysGln: 1.088 ± 0.011	1.288CysArg: 1.288 ± 0.01	2.009CysSer: 2.009 ± 0.014	1.102CysThr: 1.102 ± 0.011	1.31CysVal: 1.31 ± 0.011	0.299CysTrp: 0.299 ± 0.004	0.575CysTyr: 0.575 ± 0.006	0.0CysXaa: 0.0 ± 0.0
Asp	2.836AspAla: 2.836 ± 0.014	1.064AspCys: 1.064 ± 0.01	2.679AspAsp: 2.679 ± 0.016	3.504AspGlu: 3.504 ± 0.017	2.129AspPhe: 2.129 ± 0.012	3.315AspGly: 3.315 ± 0.022	1.143AspHis: 1.143 ± 0.007	2.656AspIle: 2.656 ± 0.014	2.605AspLys: 2.605 ± 0.013	5.043AspLeu: 5.043 ± 0.019	1.124AspMet: 1.124 ± 0.008	1.718AspAsn: 1.718 ± 0.01	2.9AspPro: 2.9 ± 0.014	1.852AspGln: 1.852 ± 0.011	2.426AspArg: 2.426 ± 0.014	4.19AspSer: 4.19 ± 0.019	2.495AspThr: 2.495 ± 0.013	3.096AspVal: 3.096 ± 0.014	0.635AspTrp: 0.635 ± 0.007	1.525AspTyr: 1.525 ± 0.011	0.0AspXaa: 0.0 ± 0.0
Glu	5.193GluAla: 5.193 ± 0.023	1.511GluCys: 1.511 ± 0.021	4.498GluAsp: 4.498 ± 0.02	8.063GluGlu: 8.063 ± 0.041	2.095GluPhe: 2.095 ± 0.012	4.2GluGly: 4.2 ± 0.017	1.534GluHis: 1.534 ± 0.009	3.271GluIle: 3.271 ± 0.02	5.614GluLys: 5.614 ± 0.032	6.533GluLeu: 6.533 ± 0.031	1.719GluMet: 1.719 ± 0.01	3.244GluAsn: 3.244 ± 0.018	3.192GluPro: 3.192 ± 0.026	3.175GluGln: 3.175 ± 0.022	4.016GluArg: 4.016 ± 0.021	4.411GluSer: 4.411 ± 0.02	3.461GluThr: 3.461 ± 0.016	4.229GluVal: 4.229 ± 0.021	0.715GluTrp: 0.715 ± 0.006	1.665GluTyr: 1.665 ± 0.015	0.0GluXaa: 0.0 ± 0.0
Phe	1.955PheAla: 1.955 ± 0.012	0.925PheCys: 0.925 ± 0.007	1.708PheAsp: 1.708 ± 0.01	2.053PheGlu: 2.053 ± 0.013	1.602PhePhe: 1.602 ± 0.011	2.205PheGly: 2.205 ± 0.014	1.058PheHis: 1.058 ± 0.008	1.845PheIle: 1.845 ± 0.012	1.841PheLys: 1.841 ± 0.01	4.059PheLeu: 4.059 ± 0.021	0.775PheMet: 0.775 ± 0.007	1.376PheAsn: 1.376 ± 0.009	1.997PhePro: 1.997 ± 0.013	1.822PheGln: 1.822 ± 0.01	2.003PheArg: 2.003 ± 0.015	3.421PheSer: 3.421 ± 0.016	2.069PheThr: 2.069 ± 0.012	2.143PheVal: 2.143 ± 0.013	0.49PheTrp: 0.49 ± 0.006	1.175PheTyr: 1.175 ± 0.008	0.0PheXaa: 0.0 ± 0.0
Gly	4.199GlyAla: 4.199 ± 0.02	1.244GlyCys: 1.244 ± 0.01	3.129GlyAsp: 3.129 ± 0.015	4.197GlyGlu: 4.197 ± 0.025	2.394GlyPhe: 2.394 ± 0.017	4.711GlyGly: 4.711 ± 0.028	1.678GlyHis: 1.678 ± 0.012	2.822GlyIle: 2.822 ± 0.014	3.907GlyLys: 3.907 ± 0.019	5.791GlyLeu: 5.791 ± 0.023	1.327GlyMet: 1.327 ± 0.01	2.381GlyAsn: 2.381 ± 0.011	4.055GlyPro: 4.055 ± 0.036	2.745GlyGln: 2.745 ± 0.017	3.612GlyArg: 3.612 ± 0.018	5.709GlySer: 5.709 ± 0.025	3.559GlyThr: 3.559 ± 0.015	3.534GlyVal: 3.534 ± 0.015	0.793GlyTrp: 0.793 ± 0.007	1.735GlyTyr: 1.735 ± 0.015	0.0GlyXaa: 0.0 ± 0.0
His	1.308HisAla: 1.308 ± 0.009	0.742HisCys: 0.742 ± 0.007	0.902HisAsp: 0.902 ± 0.007	1.349HisGlu: 1.349 ± 0.009	1.094HisPhe: 1.094 ± 0.007	1.514HisGly: 1.514 ± 0.011	0.899HisHis: 0.899 ± 0.011	1.278HisIle: 1.278 ± 0.009	1.304HisLys: 1.304 ± 0.009	2.93HisLeu: 2.93 ± 0.015	0.596HisMet: 0.596 ± 0.006	0.881HisAsn: 0.881 ± 0.006	1.657HisPro: 1.657 ± 0.011	1.375HisGln: 1.375 ± 0.013	1.582HisArg: 1.582 ± 0.009	2.314HisSer: 2.314 ± 0.014	1.561HisThr: 1.561 ± 0.016	1.494HisVal: 1.494 ± 0.009	0.353HisTrp: 0.353 ± 0.004	0.801HisTyr: 0.801 ± 0.007	0.0HisXaa: 0.0 ± 0.0
Ile	2.637IleAla: 2.637 ± 0.014	1.098IleCys: 1.098 ± 0.01	2.067IleAsp: 2.067 ± 0.013	2.692IleGlu: 2.692 ± 0.014	1.922IlePhe: 1.922 ± 0.013	2.262IleGly: 2.262 ± 0.013	1.413IleHis: 1.413 ± 0.012	2.451IleIle: 2.451 ± 0.017	2.741IleLys: 2.741 ± 0.017	4.646IleLeu: 4.646 ± 0.019	1.014IleMet: 1.014 ± 0.008	1.889IleAsn: 1.889 ± 0.013	2.647IlePro: 2.647 ± 0.012	2.353IleGln: 2.353 ± 0.012	2.404IleArg: 2.404 ± 0.012	3.773IleSer: 3.773 ± 0.016	2.65IleThr: 2.65 ± 0.017	2.551IleVal: 2.551 ± 0.016	0.517IleTrp: 0.517 ± 0.005	1.401IleTyr: 1.401 ± 0.01	0.0IleXaa: 0.0 ± 0.0
Lys	4.075LysAla: 4.075 ± 0.021	1.214LysCys: 1.214 ± 0.01	3.258LysAsp: 3.258 ± 0.019	5.316LysGlu: 5.316 ± 0.032	1.783LysPhe: 1.783 ± 0.01	3.304LysGly: 3.304 ± 0.02	1.431LysHis: 1.431 ± 0.011	2.908LysIle: 2.908 ± 0.014	4.881LysLys: 4.881 ± 0.025	5.281LysLeu: 5.281 ± 0.023	1.463LysMet: 1.463 ± 0.01	2.482LysAsn: 2.482 ± 0.013	3.203LysPro: 3.203 ± 0.02	2.689LysGln: 2.689 ± 0.016	3.363LysArg: 3.363 ± 0.016	3.962LysSer: 3.962 ± 0.023	3.197LysThr: 3.197 ± 0.018	3.576LysVal: 3.576 ± 0.02	0.624LysTrp: 0.624 ± 0.007	1.625LysTyr: 1.625 ± 0.013	0.0LysXaa: 0.0 ± 0.0
Leu	6.653LeuAla: 6.653 ± 0.028	2.199LeuCys: 2.199 ± 0.014	4.745LeuAsp: 4.745 ± 0.017	7.263LeuGlu: 7.263 ± 0.033	3.376LeuPhe: 3.376 ± 0.019	5.76LeuGly: 5.76 ± 0.026	2.737LeuHis: 2.737 ± 0.015	3.957LeuIle: 3.957 ± 0.02	5.958LeuLys: 5.958 ± 0.024	10.623LeuLeu: 10.623 ± 0.044	2.026LeuMet: 2.026 ± 0.013	3.554LeuAsn: 3.554 ± 0.016	5.931LeuPro: 5.931 ± 0.024	5.827LeuGln: 5.827 ± 0.031	5.794LeuArg: 5.794 ± 0.02	7.926LeuSer: 7.926 ± 0.024	5.121LeuThr: 5.121 ± 0.02	5.476LeuVal: 5.476 ± 0.021	1.14LeuTrp: 1.14 ± 0.008	2.552LeuTyr: 2.552 ± 0.014	0.001LeuXaa: 0.001 ± 0.0
Met	1.872MetAla: 1.872 ± 0.01	0.404MetCys: 0.404 ± 0.005	1.266MetAsp: 1.266 ± 0.009	1.914MetGlu: 1.914 ± 0.011	0.739MetPhe: 0.739 ± 0.007	1.295MetGly: 1.295 ± 0.009	0.474MetHis: 0.474 ± 0.005	0.869MetIle: 0.869 ± 0.008	1.48MetLys: 1.48 ± 0.008	1.991MetLeu: 1.991 ± 0.012	0.58MetMet: 0.58 ± 0.006	0.923MetAsn: 0.923 ± 0.008	1.096MetPro: 1.096 ± 0.009	0.935MetGln: 0.935 ± 0.007	1.048MetArg: 1.048 ± 0.007	1.547MetSer: 1.547 ± 0.011	1.148MetThr: 1.148 ± 0.008	1.412MetVal: 1.412 ± 0.009	0.241MetTrp: 0.241 ± 0.003	0.561MetTyr: 0.561 ± 0.006	0.0MetXaa: 0.0 ± 0.0
Asn	2.081AsnAla: 2.081 ± 0.011	0.851AsnCys: 0.851 ± 0.007	1.567AsnAsp: 1.567 ± 0.01	2.31AsnGlu: 2.31 ± 0.014	1.504AsnPhe: 1.504 ± 0.009	2.467AsnGly: 2.467 ± 0.017	0.963AsnHis: 0.963 ± 0.007	2.171AsnIle: 2.171 ± 0.013	2.281AsnLys: 2.281 ± 0.015	3.807AsnLeu: 3.807 ± 0.018	0.927AsnMet: 0.927 ± 0.007	1.566AsnAsn: 1.566 ± 0.011	2.206AsnPro: 2.206 ± 0.012	1.692AsnGln: 1.692 ± 0.011	1.877AsnArg: 1.877 ± 0.011	3.181AsnSer: 3.181 ± 0.017	1.995AsnThr: 1.995 ± 0.011	2.252AsnVal: 2.252 ± 0.011	0.466AsnTrp: 0.466 ± 0.005	1.155AsnTyr: 1.155 ± 0.009	0.0AsnXaa: 0.0 ± 0.0
Pro	4.585ProAla: 4.585 ± 0.024	1.126ProCys: 1.126 ± 0.011	2.77ProAsp: 2.77 ± 0.012	4.4ProGlu: 4.4 ± 0.021	1.914ProPhe: 1.914 ± 0.01	5.065ProGly: 5.065 ± 0.045	1.43ProHis: 1.43 ± 0.011	1.937ProIle: 1.937 ± 0.016	2.802ProLys: 2.802 ± 0.018	5.171ProLeu: 5.171 ± 0.022	1.036ProMet: 1.036 ± 0.009	1.856ProAsn: 1.856 ± 0.012	5.818ProPro: 5.818 ± 0.048	2.809ProGln: 2.809 ± 0.016	3.205ProArg: 3.205 ± 0.018	5.621ProSer: 5.621 ± 0.029	3.141ProThr: 3.141 ± 0.02	3.816ProVal: 3.816 ± 0.021	0.693ProTrp: 0.693 ± 0.007	1.553ProTyr: 1.553 ± 0.013	0.001ProXaa: 0.001 ± 0.0
Gln	3.525GlnAla: 3.525 ± 0.023	0.969GlnCys: 0.969 ± 0.009	2.346GlnAsp: 2.346 ± 0.012	3.978GlnGlu: 3.978 ± 0.023	1.402GlnPhe: 1.402 ± 0.009	2.842GlnGly: 2.842 ± 0.015	1.306GlnHis: 1.306 ± 0.009	2.027GlnIle: 2.027 ± 0.011	3.049GlnLys: 3.049 ± 0.017	4.758GlnLeu: 4.758 ± 0.027	1.129GlnMet: 1.129 ± 0.008	1.887GlnAsn: 1.887 ± 0.012	2.77GlnPro: 2.77 ± 0.02	3.132GlnGln: 3.132 ± 0.036	2.956GlnArg: 2.956 ± 0.018	3.143GlnSer: 3.143 ± 0.017	2.328GlnThr: 2.328 ± 0.012	2.84GlnVal: 2.84 ± 0.014	0.561GlnTrp: 0.561 ± 0.005	1.162GlnTyr: 1.162 ± 0.009	0.0GlnXaa: 0.0 ± 0.0
Arg	3.649ArgAla: 3.649 ± 0.017	1.22ArgCys: 1.22 ± 0.012	2.744ArgAsp: 2.744 ± 0.013	3.966ArgGlu: 3.966 ± 0.022	1.844ArgPhe: 1.844 ± 0.011	3.483ArgGly: 3.483 ± 0.021	1.527ArgHis: 1.527 ± 0.01	2.505ArgIle: 2.505 ± 0.013	3.717ArgLys: 3.717 ± 0.015	5.318ArgLeu: 5.318 ± 0.021	1.207ArgMet: 1.207 ± 0.008	2.156ArgAsn: 2.156 ± 0.012	3.111ArgPro: 3.111 ± 0.017	2.607ArgGln: 2.607 ± 0.015	4.155ArgArg: 4.155 ± 0.024	4.171ArgSer: 4.171 ± 0.025	2.815ArgThr: 2.815 ± 0.012	3.143ArgVal: 3.143 ± 0.021	0.701ArgTrp: 0.701 ± 0.008	1.44ArgTyr: 1.44 ± 0.009	0.0ArgXaa: 0.0 ± 0.0
Ser	5.175SerAla: 5.175 ± 0.022	1.851SerCys: 1.851 ± 0.015	3.905SerAsp: 3.905 ± 0.021	5.221SerGlu: 5.221 ± 0.022	3.064SerPhe: 3.064 ± 0.016	5.539SerGly: 5.539 ± 0.024	2.147SerHis: 2.147 ± 0.013	3.26SerIle: 3.26 ± 0.013	4.146SerLys: 4.146 ± 0.021	8.209SerLeu: 8.209 ± 0.028	1.605SerMet: 1.605 ± 0.01	2.749SerAsn: 2.749 ± 0.015	5.873SerPro: 5.873 ± 0.034	3.899SerGln: 3.899 ± 0.021	4.465SerArg: 4.465 ± 0.022	9.252SerSer: 9.252 ± 0.05	4.475SerThr: 4.475 ± 0.029	4.881SerVal: 4.881 ± 0.017	1.081SerTrp: 1.081 ± 0.009	2.073SerTyr: 2.073 ± 0.012	0.001SerXaa: 0.001 ± 0.0
Thr	3.742ThrAla: 3.742 ± 0.016	1.305ThrCys: 1.305 ± 0.014	2.507ThrAsp: 2.507 ± 0.013	3.591ThrGlu: 3.591 ± 0.015	2.118ThrPhe: 2.118 ± 0.012	3.596ThrGly: 3.596 ± 0.019	1.343ThrHis: 1.343 ± 0.011	2.456ThrIle: 2.456 ± 0.015	2.738ThrLys: 2.738 ± 0.016	5.317ThrLeu: 5.317 ± 0.017	1.125ThrMet: 1.125 ± 0.009	1.788ThrAsn: 1.788 ± 0.01	3.59ThrPro: 3.59 ± 0.029	2.32ThrGln: 2.32 ± 0.011	2.466ThrArg: 2.466 ± 0.011	4.69ThrSer: 4.69 ± 0.024	3.091ThrThr: 3.091 ± 0.029	3.879ThrVal: 3.879 ± 0.02	0.708ThrTrp: 0.708 ± 0.009	1.423ThrTyr: 1.423 ± 0.01	0.001ThrXaa: 0.001 ± 0.0
Val	4.237ValAla: 4.237 ± 0.017	1.44ValCys: 1.44 ± 0.011	2.984ValAsp: 2.984 ± 0.014	3.927ValGlu: 3.927 ± 0.022	2.427ValPhe: 2.427 ± 0.015	3.375ValGly: 3.375 ± 0.016	1.569ValHis: 1.569 ± 0.01	2.954ValIle: 2.954 ± 0.016	3.481ValLys: 3.481 ± 0.02	6.143ValLeu: 6.143 ± 0.021	1.32ValMet: 1.32 ± 0.009	2.308ValAsn: 2.308 ± 0.013	3.606ValPro: 3.606 ± 0.022	2.751ValGln: 2.751 ± 0.013	3.001ValArg: 3.001 ± 0.014	4.859ValSer: 4.859 ± 0.019	3.834ValThr: 3.834 ± 0.029	3.984ValVal: 3.984 ± 0.018	0.726ValTrp: 0.726 ± 0.007	1.628ValTyr: 1.628 ± 0.011	0.0ValXaa: 0.0 ± 0.0
Trp	0.782TrpAla: 0.782 ± 0.007	0.252TrpCys: 0.252 ± 0.003	0.659TrpAsp: 0.659 ± 0.007	0.833TrpGlu: 0.833 ± 0.008	0.448TrpPhe: 0.448 ± 0.005	0.728TrpGly: 0.728 ± 0.009	0.315TrpHis: 0.315 ± 0.004	0.55TrpIle: 0.55 ± 0.006	0.831TrpLys: 0.831 ± 0.007	1.219TrpLeu: 1.219 ± 0.009	0.318TrpMet: 0.318 ± 0.004	0.555TrpAsn: 0.555 ± 0.006	0.536TrpPro: 0.536 ± 0.006	0.54TrpGln: 0.54 ± 0.006	0.726TrpArg: 0.726 ± 0.007	0.884TrpSer: 0.884 ± 0.008	0.683TrpThr: 0.683 ± 0.008	0.705TrpVal: 0.705 ± 0.006	0.201TrpTrp: 0.201 ± 0.003	0.344TrpTyr: 0.344 ± 0.004	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.394TyrAla: 1.394 ± 0.009	0.682TyrCys: 0.682 ± 0.007	1.298TyrAsp: 1.298 ± 0.01	1.757TyrGlu: 1.757 ± 0.011	1.226TyrPhe: 1.226 ± 0.01	1.653TyrGly: 1.653 ± 0.011	0.762TyrHis: 0.762 ± 0.007	1.412TyrIle: 1.412 ± 0.013	1.56TyrLys: 1.56 ± 0.019	2.65TyrLeu: 2.65 ± 0.014	0.601TyrMet: 0.601 ± 0.006	1.122TyrAsn: 1.122 ± 0.008	1.293TyrPro: 1.293 ± 0.01	1.295TyrGln: 1.295 ± 0.01	1.631TyrArg: 1.631 ± 0.01	2.181TyrSer: 2.181 ± 0.014	1.462TyrThr: 1.462 ± 0.012	1.578TyrVal: 1.578 ± 0.01	0.367TyrTrp: 0.367 ± 0.006	0.941TyrTyr: 0.941 ± 0.008	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.001XaaPhe: 0.001 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.274XaaXaa: 0.274 ± 0.052

Statistics based on 40661 proteins (21213084 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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