Amino acid dipepetide frequency for Beihai rhabdo-like virus 4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.759AlaAla: 3.759 ± 3.315
1.128AlaCys: 1.128 ± 0.614
3.008AlaAsp: 3.008 ± 0.84
3.383AlaGlu: 3.383 ± 0.991
4.135AlaPhe: 4.135 ± 1.643
3.759AlaGly: 3.759 ± 2.647
1.128AlaHis: 1.128 ± 0.837
4.887AlaIle: 4.887 ± 0.366
4.511AlaLys: 4.511 ± 1.312
5.639AlaLeu: 5.639 ± 1.752
2.632AlaMet: 2.632 ± 0.563
0.752AlaAsn: 0.752 ± 0.409
1.128AlaPro: 1.128 ± 1.26
3.008AlaGln: 3.008 ± 1.184
2.256AlaArg: 2.256 ± 1.101
4.511AlaSer: 4.511 ± 1.072
3.008AlaThr: 3.008 ± 0.656
4.511AlaVal: 4.511 ± 0.469
1.504AlaTrp: 1.504 ± 0.328
1.504AlaTyr: 1.504 ± 1.335
0.0AlaXaa: 0.0 ± 0.0
Cys
2.256CysAla: 2.256 ± 1.673
0.376CysCys: 0.376 ± 0.205
1.88CysAsp: 1.88 ± 0.477
1.128CysGlu: 1.128 ± 1.183
0.376CysPhe: 0.376 ± 0.205
1.128CysGly: 1.128 ± 0.614
0.752CysHis: 0.752 ± 1.245
1.504CysIle: 1.504 ± 0.328
0.752CysLys: 0.752 ± 1.245
1.88CysLeu: 1.88 ± 1.023
0.752CysMet: 0.752 ± 0.801
0.752CysAsn: 0.752 ± 0.346
0.376CysPro: 0.376 ± 0.205
0.0CysGln: 0.0 ± 0.0
1.88CysArg: 1.88 ± 1.01
1.128CysSer: 1.128 ± 0.614
1.128CysThr: 1.128 ± 0.614
0.752CysVal: 0.752 ± 0.409
0.0CysTrp: 0.0 ± 0.0
1.504CysTyr: 1.504 ± 1.153
0.0CysXaa: 0.0 ± 0.0
Asp
3.383AspAla: 3.383 ± 0.804
0.752AspCys: 0.752 ± 0.346
3.759AspAsp: 3.759 ± 0.953
4.511AspGlu: 4.511 ± 2.203
3.759AspPhe: 3.759 ± 1.442
2.632AspGly: 2.632 ± 0.939
1.88AspHis: 1.88 ± 0.477
2.632AspIle: 2.632 ± 0.847
2.256AspLys: 2.256 ± 1.227
9.398AspLeu: 9.398 ± 1.27
0.0AspMet: 0.0 ± 0.0
2.632AspAsn: 2.632 ± 2.379
2.632AspPro: 2.632 ± 1.522
3.008AspGln: 3.008 ± 2.014
6.391AspArg: 6.391 ± 3.247
1.128AspSer: 1.128 ± 0.268
3.008AspThr: 3.008 ± 1.043
4.511AspVal: 4.511 ± 0.984
0.752AspTrp: 0.752 ± 0.409
3.008AspTyr: 3.008 ± 1.043
0.0AspXaa: 0.0 ± 0.0
Glu
3.008GluAla: 3.008 ± 1.762
0.0GluCys: 0.0 ± 0.0
3.383GluAsp: 3.383 ± 2.849
3.383GluGlu: 3.383 ± 1.866
3.383GluPhe: 3.383 ± 0.685
4.135GluGly: 4.135 ± 0.882
0.752GluHis: 0.752 ± 0.409
3.008GluIle: 3.008 ± 0.656
3.759GluLys: 3.759 ± 0.953
6.391GluLeu: 6.391 ± 1.943
2.256GluMet: 2.256 ± 0.656
1.128GluAsn: 1.128 ± 0.614
1.504GluPro: 1.504 ± 0.328
0.376GluGln: 0.376 ± 0.205
4.511GluArg: 4.511 ± 2.637
3.759GluSer: 3.759 ± 1.73
3.383GluThr: 3.383 ± 2.127
5.639GluVal: 5.639 ± 1.889
0.376GluTrp: 0.376 ± 0.205
3.759GluTyr: 3.759 ± 1.442
0.0GluXaa: 0.0 ± 0.0
Phe
1.504PheAla: 1.504 ± 0.328
1.128PheCys: 1.128 ± 0.268
3.383PheAsp: 3.383 ± 0.792
3.008PheGlu: 3.008 ± 1.636
2.632PhePhe: 2.632 ± 1.432
1.88PheGly: 1.88 ± 0.477
1.128PheHis: 1.128 ± 0.614
2.256PheIle: 2.256 ± 0.656
1.88PheLys: 1.88 ± 1.16
4.135PheLeu: 4.135 ± 0.625
1.128PheMet: 1.128 ± 0.614
2.632PheAsn: 2.632 ± 0.922
2.256PhePro: 2.256 ± 0.536
1.88PheGln: 1.88 ± 1.16
2.632PheArg: 2.632 ± 2.327
2.632PheSer: 2.632 ± 1.432
2.256PheThr: 2.256 ± 1.038
2.632PheVal: 2.632 ± 1.432
0.752PheTrp: 0.752 ± 0.346
0.752PheTyr: 0.752 ± 0.409
0.0PheXaa: 0.0 ± 0.0
Gly
1.88GlyAla: 1.88 ± 1.01
0.752GlyCys: 0.752 ± 0.409
5.263GlyAsp: 5.263 ± 1.878
3.383GlyGlu: 3.383 ± 1.264
1.128GlyPhe: 1.128 ± 0.268
7.895GlyGly: 7.895 ± 8.456
1.128GlyHis: 1.128 ± 0.268
3.008GlyIle: 3.008 ± 1.184
1.504GlyLys: 1.504 ± 0.328
6.015GlyLeu: 6.015 ± 0.613
2.256GlyMet: 2.256 ± 1.176
1.88GlyAsn: 1.88 ± 1.023
2.632GlyPro: 2.632 ± 1.381
3.759GlyGln: 3.759 ± 1.168
5.263GlyArg: 5.263 ± 3.203
3.759GlySer: 3.759 ± 0.819
2.256GlyThr: 2.256 ± 1.038
5.639GlyVal: 5.639 ± 1.114
1.504GlyTrp: 1.504 ± 0.328
1.88GlyTyr: 1.88 ± 2.455
0.0GlyXaa: 0.0 ± 0.0
His
0.752HisAla: 0.752 ± 0.409
0.0HisCys: 0.0 ± 0.0
1.128HisAsp: 1.128 ± 0.614
2.256HisGlu: 2.256 ± 0.656
1.504HisPhe: 1.504 ± 0.818
0.752HisGly: 0.752 ± 0.346
0.0HisHis: 0.0 ± 0.0
0.752HisIle: 0.752 ± 0.346
1.504HisLys: 1.504 ± 0.328
4.511HisLeu: 4.511 ± 0.692
0.752HisMet: 0.752 ± 0.409
2.256HisAsn: 2.256 ± 1.227
0.752HisPro: 0.752 ± 0.409
0.752HisGln: 0.752 ± 0.409
1.88HisArg: 1.88 ± 0.477
1.128HisSer: 1.128 ± 0.614
1.504HisThr: 1.504 ± 1.153
1.504HisVal: 1.504 ± 1.153
0.376HisTrp: 0.376 ± 0.205
1.128HisTyr: 1.128 ± 0.268
0.0HisXaa: 0.0 ± 0.0
Ile
4.887IleAla: 4.887 ± 1.448
1.88IleCys: 1.88 ± 1.023
1.88IleAsp: 1.88 ± 0.584
3.383IleGlu: 3.383 ± 0.804
0.752IlePhe: 0.752 ± 0.409
3.008IleGly: 3.008 ± 1.636
2.256IleHis: 2.256 ± 1.202
3.383IleIle: 3.383 ± 1.242
3.759IleLys: 3.759 ± 0.819
6.015IleLeu: 6.015 ± 0.148
2.256IleMet: 2.256 ± 0.656
2.632IleAsn: 2.632 ± 0.922
3.008IlePro: 3.008 ± 1.636
2.256IleGln: 2.256 ± 0.536
3.383IleArg: 3.383 ± 2.304
4.135IleSer: 4.135 ± 2.375
2.256IleThr: 2.256 ± 0.656
2.632IleVal: 2.632 ± 0.563
0.752IleTrp: 0.752 ± 0.409
1.88IleTyr: 1.88 ± 1.01
0.0IleXaa: 0.0 ± 0.0
Lys
1.128LysAla: 1.128 ± 0.268
1.504LysCys: 1.504 ± 0.818
3.759LysAsp: 3.759 ± 0.819
3.383LysGlu: 3.383 ± 0.804
1.88LysPhe: 1.88 ± 0.584
3.383LysGly: 3.383 ± 0.685
0.376LysHis: 0.376 ± 0.205
3.759LysIle: 3.759 ± 2.045
3.759LysLys: 3.759 ± 1.442
6.015LysLeu: 6.015 ± 1.97
0.752LysMet: 0.752 ± 0.346
4.135LysAsn: 4.135 ± 1.128
3.008LysPro: 3.008 ± 1.384
2.256LysGln: 2.256 ± 0.536
6.015LysArg: 6.015 ± 0.148
4.887LysSer: 4.887 ± 0.366
3.383LysThr: 3.383 ± 0.792
6.015LysVal: 6.015 ± 0.775
1.504LysTrp: 1.504 ± 0.328
3.759LysTyr: 3.759 ± 1.442
0.0LysXaa: 0.0 ± 0.0
Leu
6.015LeuAla: 6.015 ± 0.148
2.256LeuCys: 2.256 ± 0.536
5.263LeuAsp: 5.263 ± 1.126
6.391LeuGlu: 6.391 ± 1.472
3.383LeuPhe: 3.383 ± 0.792
5.639LeuGly: 5.639 ± 1.729
2.256LeuHis: 2.256 ± 1.202
3.759LeuIle: 3.759 ± 0.819
7.895LeuLys: 7.895 ± 2.503
6.391LeuLeu: 6.391 ± 1.379
3.008LeuMet: 3.008 ± 0.745
2.632LeuAsn: 2.632 ± 1.432
5.263LeuPro: 5.263 ± 0.362
4.135LeuGln: 4.135 ± 1.15
9.023LeuArg: 9.023 ± 1.942
6.391LeuSer: 6.391 ± 0.579
5.263LeuThr: 5.263 ± 2.29
3.759LeuVal: 3.759 ± 0.953
1.128LeuTrp: 1.128 ± 1.183
6.015LeuTyr: 6.015 ± 1.289
0.0LeuXaa: 0.0 ± 0.0
Met
1.504MetAla: 1.504 ± 1.335
0.0MetCys: 0.0 ± 0.0
1.128MetAsp: 1.128 ± 0.268
0.376MetGlu: 0.376 ± 0.501
0.376MetPhe: 0.376 ± 0.205
1.128MetGly: 1.128 ± 0.614
0.752MetHis: 0.752 ± 0.409
1.504MetIle: 1.504 ± 0.328
2.256MetLys: 2.256 ± 1.227
2.256MetLeu: 2.256 ± 0.656
0.752MetMet: 0.752 ± 0.346
2.632MetAsn: 2.632 ± 1.432
1.88MetPro: 1.88 ± 0.584
1.128MetGln: 1.128 ± 0.268
2.256MetArg: 2.256 ± 0.536
2.256MetSer: 2.256 ± 1.101
2.632MetThr: 2.632 ± 0.563
1.504MetVal: 1.504 ± 0.818
0.376MetTrp: 0.376 ± 0.205
1.504MetTyr: 1.504 ± 0.818
0.0MetXaa: 0.0 ± 0.0
Asn
2.256AsnAla: 2.256 ± 1.038
0.752AsnCys: 0.752 ± 0.409
1.128AsnAsp: 1.128 ± 0.268
1.504AsnGlu: 1.504 ± 0.818
1.88AsnPhe: 1.88 ± 1.01
1.88AsnGly: 1.88 ± 1.16
1.504AsnHis: 1.504 ± 0.818
3.759AsnIle: 3.759 ± 0.624
4.511AsnLys: 4.511 ± 1.312
6.015AsnLeu: 6.015 ± 2.086
1.128AsnMet: 1.128 ± 0.268
0.752AsnAsn: 0.752 ± 0.409
3.008AsnPro: 3.008 ± 1.184
1.128AsnGln: 1.128 ± 0.614
2.256AsnArg: 2.256 ± 0.536
3.008AsnSer: 3.008 ± 0.656
1.88AsnThr: 1.88 ± 1.023
0.752AsnVal: 0.752 ± 0.346
0.0AsnTrp: 0.0 ± 0.0
0.752AsnTyr: 0.752 ± 0.346
0.0AsnXaa: 0.0 ± 0.0
Pro
4.511ProAla: 4.511 ± 1.504
0.0ProCys: 0.0 ± 0.0
4.511ProAsp: 4.511 ± 1.312
2.256ProGlu: 2.256 ± 1.673
1.128ProPhe: 1.128 ± 0.614
3.759ProGly: 3.759 ± 0.819
2.632ProHis: 2.632 ± 0.563
2.256ProIle: 2.256 ± 1.202
5.263ProLys: 5.263 ± 1.367
2.256ProLeu: 2.256 ± 1.038
0.752ProMet: 0.752 ± 1.002
0.752ProAsn: 0.752 ± 0.346
1.128ProPro: 1.128 ± 0.614
2.256ProGln: 2.256 ± 2.347
2.632ProArg: 2.632 ± 1.966
3.008ProSer: 3.008 ± 2.247
2.256ProThr: 2.256 ± 2.347
1.504ProVal: 1.504 ± 0.692
0.0ProTrp: 0.0 ± 0.0
1.504ProTyr: 1.504 ± 1.124
0.0ProXaa: 0.0 ± 0.0
Gln
3.383GlnAla: 3.383 ± 0.991
1.504GlnCys: 1.504 ± 0.818
3.383GlnAsp: 3.383 ± 1.264
1.128GlnGlu: 1.128 ± 0.837
0.752GlnPhe: 0.752 ± 0.409
3.008GlnGly: 3.008 ± 1.384
0.376GlnHis: 0.376 ± 0.205
1.128GlnIle: 1.128 ± 0.837
1.504GlnLys: 1.504 ± 0.328
3.008GlnLeu: 3.008 ± 0.656
1.128GlnMet: 1.128 ± 1.504
1.504GlnAsn: 1.504 ± 1.124
1.88GlnPro: 1.88 ± 1.276
0.752GlnGln: 0.752 ± 0.346
2.256GlnArg: 2.256 ± 1.101
2.256GlnSer: 2.256 ± 1.227
3.008GlnThr: 3.008 ± 0.893
1.88GlnVal: 1.88 ± 1.16
0.376GlnTrp: 0.376 ± 0.501
0.376GlnTyr: 0.376 ± 0.205
0.0GlnXaa: 0.0 ± 0.0
Arg
4.135ArgAla: 4.135 ± 1.608
1.128ArgCys: 1.128 ± 1.183
4.887ArgAsp: 4.887 ± 2.045
6.767ArgGlu: 6.767 ± 1.755
3.008ArgPhe: 3.008 ± 2.172
7.895ArgGly: 7.895 ± 1.894
1.88ArgHis: 1.88 ± 1.023
3.383ArgIle: 3.383 ± 2.127
3.383ArgLys: 3.383 ± 1.264
5.263ArgLeu: 5.263 ± 0.95
1.504ArgMet: 1.504 ± 0.818
3.383ArgAsn: 3.383 ± 1.264
4.135ArgPro: 4.135 ± 4.126
1.88ArgGln: 1.88 ± 1.01
6.015ArgArg: 6.015 ± 2.369
5.639ArgSer: 5.639 ± 1.206
1.88ArgThr: 1.88 ± 0.477
4.511ArgVal: 4.511 ± 2.036
0.752ArgTrp: 0.752 ± 0.409
1.128ArgTyr: 1.128 ± 0.837
0.0ArgXaa: 0.0 ± 0.0
Ser
4.511SerAla: 4.511 ± 0.946
0.752SerCys: 0.752 ± 0.409
4.887SerAsp: 4.887 ± 0.742
3.008SerGlu: 3.008 ± 1.762
3.759SerPhe: 3.759 ± 0.953
3.759SerGly: 3.759 ± 2.552
1.88SerHis: 1.88 ± 1.023
5.263SerIle: 5.263 ± 1.266
3.383SerLys: 3.383 ± 1.242
7.895SerLeu: 7.895 ± 0.578
2.632SerMet: 2.632 ± 1.432
3.008SerAsn: 3.008 ± 0.796
1.128SerPro: 1.128 ± 0.268
2.256SerGln: 2.256 ± 0.536
4.511SerArg: 4.511 ± 1.857
7.895SerSer: 7.895 ± 0.328
3.383SerThr: 3.383 ± 0.804
4.887SerVal: 4.887 ± 2.116
0.0SerTrp: 0.0 ± 0.0
1.128SerTyr: 1.128 ± 0.268
0.0SerXaa: 0.0 ± 0.0
Thr
4.135ThrAla: 4.135 ± 2.25
1.88ThrCys: 1.88 ± 1.01
4.887ThrAsp: 4.887 ± 1.501
4.887ThrGlu: 4.887 ± 0.742
3.008ThrPhe: 3.008 ± 0.893
1.504ThrGly: 1.504 ± 2.005
1.504ThrHis: 1.504 ± 0.818
3.008ThrIle: 3.008 ± 1.376
4.135ThrLys: 4.135 ± 1.608
3.759ThrLeu: 3.759 ± 0.624
0.752ThrMet: 0.752 ± 0.409
1.504ThrAsn: 1.504 ± 0.818
4.135ThrPro: 4.135 ± 1.15
1.128ThrGln: 1.128 ± 0.268
2.256ThrArg: 2.256 ± 0.536
1.88ThrSer: 1.88 ± 1.023
1.504ThrThr: 1.504 ± 0.818
3.759ThrVal: 3.759 ± 2.32
1.504ThrTrp: 1.504 ± 1.153
1.128ThrTyr: 1.128 ± 1.183
0.0ThrXaa: 0.0 ± 0.0
Val
2.632ValAla: 2.632 ± 1.381
1.128ValCys: 1.128 ± 2.576
3.008ValAsp: 3.008 ± 0.796
1.88ValGlu: 1.88 ± 1.023
3.759ValPhe: 3.759 ± 0.953
4.887ValGly: 4.887 ± 1.448
1.504ValHis: 1.504 ± 0.328
3.008ValIle: 3.008 ± 1.636
5.639ValLys: 5.639 ± 1.79
5.263ValLeu: 5.263 ± 1.615
2.256ValMet: 2.256 ± 0.656
3.759ValAsn: 3.759 ± 0.953
2.256ValPro: 2.256 ± 0.536
0.752ValGln: 0.752 ± 0.409
4.887ValArg: 4.887 ± 0.806
6.391ValSer: 6.391 ± 1.51
3.383ValThr: 3.383 ± 0.943
4.135ValVal: 4.135 ± 1.643
0.752ValTrp: 0.752 ± 1.002
1.504ValTyr: 1.504 ± 0.818
0.0ValXaa: 0.0 ± 0.0
Trp
1.88TrpAla: 1.88 ± 0.477
0.752TrpCys: 0.752 ± 1.245
0.0TrpAsp: 0.0 ± 0.0
1.128TrpGlu: 1.128 ± 0.268
0.752TrpPhe: 0.752 ± 0.346
0.752TrpGly: 0.752 ± 0.409
0.0TrpHis: 0.0 ± 0.0
0.376TrpIle: 0.376 ± 0.205
1.128TrpLys: 1.128 ± 0.268
0.376TrpLeu: 0.376 ± 0.205
0.376TrpMet: 0.376 ± 0.205
0.0TrpAsn: 0.0 ± 0.0
0.376TrpPro: 0.376 ± 0.205
0.376TrpGln: 0.376 ± 0.501
0.0TrpArg: 0.0 ± 0.0
1.128TrpSer: 1.128 ± 1.183
2.256TrpThr: 2.256 ± 0.536
0.752TrpVal: 0.752 ± 0.409
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.632TyrAla: 2.632 ± 0.847
3.008TyrCys: 3.008 ± 1.184
1.504TyrAsp: 1.504 ± 0.818
0.752TyrGlu: 0.752 ± 0.409
1.128TyrPhe: 1.128 ± 0.268
0.0TyrGly: 0.0 ± 0.0
1.504TyrHis: 1.504 ± 0.328
3.759TyrIle: 3.759 ± 0.624
1.88TyrLys: 1.88 ± 1.023
3.383TyrLeu: 3.383 ± 2.127
0.752TyrMet: 0.752 ± 0.346
1.128TyrAsn: 1.128 ± 0.614
1.88TyrPro: 1.88 ± 0.477
1.504TyrGln: 1.504 ± 0.328
2.256TyrArg: 2.256 ± 1.227
3.008TyrSer: 3.008 ± 1.043
2.632TyrThr: 2.632 ± 2.252
1.504TyrVal: 1.504 ± 1.124
0.0TyrTrp: 0.0 ± 0.0
1.128TyrTyr: 1.128 ± 0.614
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (2661 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski