Amino acid dipepetide frequency for Drosophila unispina virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.242AlaAla: 1.242 ± 0.667
0.0AlaCys: 0.0 ± 0.0
2.484AlaAsp: 2.484 ± 0.61
2.981AlaGlu: 2.981 ± 0.736
1.49AlaPhe: 1.49 ± 0.443
2.235AlaGly: 2.235 ± 1.316
0.497AlaHis: 0.497 ± 0.504
1.739AlaIle: 1.739 ± 0.695
2.235AlaLys: 2.235 ± 2.12
1.739AlaLeu: 1.739 ± 0.551
0.994AlaMet: 0.994 ± 0.294
3.726AlaAsn: 3.726 ± 0.693
1.49AlaPro: 1.49 ± 0.581
1.739AlaGln: 1.739 ± 0.483
1.987AlaArg: 1.987 ± 0.963
1.242AlaSer: 1.242 ± 0.323
2.235AlaThr: 2.235 ± 1.21
1.242AlaVal: 1.242 ± 0.772
0.745AlaTrp: 0.745 ± 0.643
1.242AlaTyr: 1.242 ± 0.601
0.0AlaXaa: 0.0 ± 0.0
Cys
0.745CysAla: 0.745 ± 0.464
0.0CysCys: 0.0 ± 0.0
1.242CysAsp: 1.242 ± 0.522
0.745CysGlu: 0.745 ± 0.329
1.242CysPhe: 1.242 ± 0.536
0.994CysGly: 0.994 ± 0.56
0.994CysHis: 0.994 ± 0.498
1.242CysIle: 1.242 ± 0.522
2.484CysLys: 2.484 ± 0.401
2.235CysLeu: 2.235 ± 0.682
0.0CysMet: 0.0 ± 0.0
1.739CysAsn: 1.739 ± 0.814
1.49CysPro: 1.49 ± 0.598
0.745CysGln: 0.745 ± 0.301
0.994CysArg: 0.994 ± 0.453
0.994CysSer: 0.994 ± 0.29
0.497CysThr: 0.497 ± 0.253
0.994CysVal: 0.994 ± 0.63
0.745CysTrp: 0.745 ± 0.31
1.242CysTyr: 1.242 ± 1.034
0.0CysXaa: 0.0 ± 0.0
Asp
2.981AspAla: 2.981 ± 0.712
1.242AspCys: 1.242 ± 0.536
2.235AspAsp: 2.235 ± 1.049
1.242AspGlu: 1.242 ± 0.516
2.235AspPhe: 2.235 ± 1.009
2.235AspGly: 2.235 ± 0.836
1.49AspHis: 1.49 ± 0.882
4.223AspIle: 4.223 ± 0.915
4.223AspLys: 4.223 ± 2.139
6.458AspLeu: 6.458 ± 1.257
0.745AspMet: 0.745 ± 0.441
4.223AspAsn: 4.223 ± 1.125
1.739AspPro: 1.739 ± 0.389
1.987AspGln: 1.987 ± 1.001
2.235AspArg: 2.235 ± 0.634
3.974AspSer: 3.974 ± 1.066
3.974AspThr: 3.974 ± 0.843
2.235AspVal: 2.235 ± 0.732
0.248AspTrp: 0.248 ± 0.147
2.235AspTyr: 2.235 ± 0.605
0.0AspXaa: 0.0 ± 0.0
Glu
1.49GluAla: 1.49 ± 0.62
1.987GluCys: 1.987 ± 0.524
3.477GluAsp: 3.477 ± 0.948
4.968GluGlu: 4.968 ± 1.032
3.229GluPhe: 3.229 ± 0.676
3.974GluGly: 3.974 ± 1.046
0.497GluHis: 0.497 ± 0.419
5.713GluIle: 5.713 ± 1.258
5.216GluLys: 5.216 ± 1.292
6.21GluLeu: 6.21 ± 0.827
2.235GluMet: 2.235 ± 0.455
4.223GluAsn: 4.223 ± 0.947
0.497GluPro: 0.497 ± 0.253
1.49GluGln: 1.49 ± 0.64
1.987GluArg: 1.987 ± 0.547
4.223GluSer: 4.223 ± 1.233
4.968GluThr: 4.968 ± 1.058
4.471GluVal: 4.471 ± 2.351
0.994GluTrp: 0.994 ± 0.632
2.235GluTyr: 2.235 ± 1.159
0.0GluXaa: 0.0 ± 0.0
Phe
3.477PheAla: 3.477 ± 1.796
1.739PheCys: 1.739 ± 0.475
2.981PheAsp: 2.981 ± 1.004
2.235PheGlu: 2.235 ± 0.605
1.242PhePhe: 1.242 ± 0.516
1.987PheGly: 1.987 ± 0.441
0.248PheHis: 0.248 ± 0.371
3.477PheIle: 3.477 ± 1.04
2.235PheLys: 2.235 ± 0.919
5.464PheLeu: 5.464 ± 0.974
0.497PheMet: 0.497 ± 0.568
1.242PheAsn: 1.242 ± 0.477
1.987PhePro: 1.987 ± 0.933
0.745PheGln: 0.745 ± 0.329
2.732PheArg: 2.732 ± 0.717
5.464PheSer: 5.464 ± 1.345
1.49PheThr: 1.49 ± 0.443
1.987PheVal: 1.987 ± 0.541
0.745PheTrp: 0.745 ± 0.625
1.49PheTyr: 1.49 ± 0.487
0.0PheXaa: 0.0 ± 0.0
Gly
1.987GlyAla: 1.987 ± 0.841
0.994GlyCys: 0.994 ± 0.407
2.235GlyAsp: 2.235 ± 0.69
2.732GlyGlu: 2.732 ± 0.803
3.229GlyPhe: 3.229 ± 1.462
3.974GlyGly: 3.974 ± 0.913
0.994GlyHis: 0.994 ± 0.407
5.464GlyIle: 5.464 ± 0.824
4.223GlyLys: 4.223 ± 1.137
3.974GlyLeu: 3.974 ± 0.516
1.739GlyMet: 1.739 ± 0.305
3.229GlyAsn: 3.229 ± 0.477
1.49GlyPro: 1.49 ± 0.798
1.49GlyGln: 1.49 ± 0.742
2.235GlyArg: 2.235 ± 0.579
4.223GlySer: 4.223 ± 1.112
2.981GlyThr: 2.981 ± 1.175
1.987GlyVal: 1.987 ± 1.19
0.248GlyTrp: 0.248 ± 0.445
2.235GlyTyr: 2.235 ± 0.753
0.0GlyXaa: 0.0 ± 0.0
His
0.994HisAla: 0.994 ± 0.688
0.497HisCys: 0.497 ± 0.586
1.49HisAsp: 1.49 ± 0.564
0.745HisGlu: 0.745 ± 0.556
1.242HisPhe: 1.242 ± 0.536
1.49HisGly: 1.49 ± 1.004
0.745HisHis: 0.745 ± 0.352
0.994HisIle: 0.994 ± 0.4
1.242HisLys: 1.242 ± 0.598
1.987HisLeu: 1.987 ± 0.665
0.0HisMet: 0.0 ± 0.0
0.745HisAsn: 0.745 ± 0.502
1.242HisPro: 1.242 ± 0.303
2.235HisGln: 2.235 ± 0.605
1.242HisArg: 1.242 ± 0.735
1.49HisSer: 1.49 ± 0.444
0.248HisThr: 0.248 ± 0.371
1.242HisVal: 1.242 ± 0.522
0.248HisTrp: 0.248 ± 0.147
1.739HisTyr: 1.739 ± 0.575
0.0HisXaa: 0.0 ± 0.0
Ile
2.235IleAla: 2.235 ± 0.934
2.235IleCys: 2.235 ± 0.605
4.968IleAsp: 4.968 ± 0.992
4.719IleGlu: 4.719 ± 0.698
2.235IlePhe: 2.235 ± 0.704
4.719IleGly: 4.719 ± 0.773
1.739IleHis: 1.739 ± 0.483
7.203IleIle: 7.203 ± 2.069
6.458IleLys: 6.458 ± 1.73
6.458IleLeu: 6.458 ± 1.027
2.235IleMet: 2.235 ± 1.151
6.21IleAsn: 6.21 ± 0.732
4.223IlePro: 4.223 ± 0.641
2.235IleGln: 2.235 ± 0.634
7.203IleArg: 7.203 ± 1.572
6.955IleSer: 6.955 ± 2.15
5.961IleThr: 5.961 ± 1.599
3.974IleVal: 3.974 ± 1.208
0.994IleTrp: 0.994 ± 1.052
2.732IleTyr: 2.732 ± 0.866
0.0IleXaa: 0.0 ± 0.0
Lys
2.484LysAla: 2.484 ± 0.817
1.987LysCys: 1.987 ± 0.587
3.974LysAsp: 3.974 ± 0.822
4.968LysGlu: 4.968 ± 0.786
3.477LysPhe: 3.477 ± 1.489
4.223LysGly: 4.223 ± 0.939
0.994LysHis: 0.994 ± 0.375
8.197LysIle: 8.197 ± 1.432
3.477LysLys: 3.477 ± 0.938
7.203LysLeu: 7.203 ± 0.501
1.987LysMet: 1.987 ± 0.517
5.961LysAsn: 5.961 ± 1.685
2.235LysPro: 2.235 ± 0.275
1.987LysGln: 1.987 ± 0.659
3.229LysArg: 3.229 ± 1.248
3.974LysSer: 3.974 ± 1.379
3.974LysThr: 3.974 ± 0.611
3.477LysVal: 3.477 ± 0.909
1.242LysTrp: 1.242 ± 0.601
2.981LysTyr: 2.981 ± 1.129
0.0LysXaa: 0.0 ± 0.0
Leu
3.477LeuAla: 3.477 ± 1.039
0.994LeuCys: 0.994 ± 0.294
5.464LeuAsp: 5.464 ± 0.712
4.719LeuGlu: 4.719 ± 1.311
5.961LeuPhe: 5.961 ± 1.884
4.719LeuGly: 4.719 ± 1.848
2.732LeuHis: 2.732 ± 0.381
10.184LeuIle: 10.184 ± 0.605
7.7LeuLys: 7.7 ± 2.175
8.942LeuLeu: 8.942 ± 0.698
2.732LeuMet: 2.732 ± 0.841
6.706LeuAsn: 6.706 ± 1.46
4.968LeuPro: 4.968 ± 1.377
3.726LeuGln: 3.726 ± 0.593
3.477LeuArg: 3.477 ± 0.313
7.948LeuSer: 7.948 ± 1.43
5.464LeuThr: 5.464 ± 0.923
4.471LeuVal: 4.471 ± 1.271
0.497LeuTrp: 0.497 ± 0.307
4.719LeuTyr: 4.719 ± 1.18
0.0LeuXaa: 0.0 ± 0.0
Met
0.497MetAla: 0.497 ± 0.742
0.248MetCys: 0.248 ± 0.147
0.497MetAsp: 0.497 ± 0.419
1.739MetGlu: 1.739 ± 0.634
0.745MetPhe: 0.745 ± 0.301
2.235MetGly: 2.235 ± 0.818
0.248MetHis: 0.248 ± 0.147
1.49MetIle: 1.49 ± 0.62
2.484MetLys: 2.484 ± 1.086
2.484MetLeu: 2.484 ± 1.147
0.497MetMet: 0.497 ± 0.253
0.497MetAsn: 0.497 ± 0.419
1.242MetPro: 1.242 ± 1.216
0.745MetGln: 0.745 ± 0.441
0.745MetArg: 0.745 ± 0.4
3.477MetSer: 3.477 ± 0.901
1.739MetThr: 1.739 ± 0.772
1.739MetVal: 1.739 ± 0.459
0.994MetTrp: 0.994 ± 0.588
0.745MetTyr: 0.745 ± 0.517
0.0MetXaa: 0.0 ± 0.0
Asn
2.484AsnAla: 2.484 ± 1.291
0.745AsnCys: 0.745 ± 0.352
3.477AsnAsp: 3.477 ± 0.646
5.713AsnGlu: 5.713 ± 2.743
3.477AsnPhe: 3.477 ± 0.732
1.987AsnGly: 1.987 ± 0.506
2.235AsnHis: 2.235 ± 0.392
6.21AsnIle: 6.21 ± 1.476
5.961AsnLys: 5.961 ± 0.763
5.464AsnLeu: 5.464 ± 1.706
1.242AsnMet: 1.242 ± 0.323
3.726AsnAsn: 3.726 ± 1.198
1.49AsnPro: 1.49 ± 0.487
3.477AsnGln: 3.477 ± 1.106
3.726AsnArg: 3.726 ± 1.032
4.968AsnSer: 4.968 ± 0.682
4.223AsnThr: 4.223 ± 1.166
0.745AsnVal: 0.745 ± 0.643
1.242AsnTrp: 1.242 ± 0.598
3.229AsnTyr: 3.229 ± 0.921
0.0AsnXaa: 0.0 ± 0.0
Pro
0.745ProAla: 0.745 ± 0.441
1.242ProCys: 1.242 ± 0.323
2.484ProAsp: 2.484 ± 0.726
3.477ProGlu: 3.477 ± 0.758
0.994ProPhe: 0.994 ± 0.858
1.242ProGly: 1.242 ± 0.303
0.745ProHis: 0.745 ± 0.556
3.974ProIle: 3.974 ± 1.143
2.484ProLys: 2.484 ± 0.359
3.229ProLeu: 3.229 ± 0.629
0.745ProMet: 0.745 ± 0.329
1.49ProAsn: 1.49 ± 0.443
1.987ProPro: 1.987 ± 0.865
1.987ProGln: 1.987 ± 0.462
1.242ProArg: 1.242 ± 0.601
2.484ProSer: 2.484 ± 0.962
2.484ProThr: 2.484 ± 0.349
1.987ProVal: 1.987 ± 0.519
0.745ProTrp: 0.745 ± 0.329
1.739ProTyr: 1.739 ± 0.571
0.0ProXaa: 0.0 ± 0.0
Gln
0.248GlnAla: 0.248 ± 0.445
0.745GlnCys: 0.745 ± 0.4
0.745GlnAsp: 0.745 ± 0.517
2.981GlnGlu: 2.981 ± 0.334
1.987GlnPhe: 1.987 ± 0.58
2.235GlnGly: 2.235 ± 1.099
0.497GlnHis: 0.497 ± 0.397
3.229GlnIle: 3.229 ± 0.659
2.484GlnLys: 2.484 ± 0.684
6.21GlnLeu: 6.21 ± 0.912
1.49GlnMet: 1.49 ± 0.553
2.235GlnAsn: 2.235 ± 1.031
1.987GlnPro: 1.987 ± 0.27
0.745GlnGln: 0.745 ± 0.31
1.987GlnArg: 1.987 ± 0.865
1.49GlnSer: 1.49 ± 0.882
1.987GlnThr: 1.987 ± 0.586
2.235GlnVal: 2.235 ± 0.593
0.497GlnTrp: 0.497 ± 0.309
1.49GlnTyr: 1.49 ± 0.802
0.0GlnXaa: 0.0 ± 0.0
Arg
0.745ArgAla: 0.745 ± 0.301
1.49ArgCys: 1.49 ± 0.601
2.981ArgAsp: 2.981 ± 0.555
3.726ArgGlu: 3.726 ± 0.969
1.49ArgPhe: 1.49 ± 0.375
2.981ArgGly: 2.981 ± 0.751
0.994ArgHis: 0.994 ± 0.407
4.223ArgIle: 4.223 ± 1.582
4.223ArgLys: 4.223 ± 2.008
3.477ArgLeu: 3.477 ± 0.95
0.745ArgMet: 0.745 ± 0.541
2.235ArgAsn: 2.235 ± 0.265
0.745ArgPro: 0.745 ± 0.517
1.987ArgGln: 1.987 ± 0.27
1.987ArgArg: 1.987 ± 0.519
2.235ArgSer: 2.235 ± 0.518
2.484ArgThr: 2.484 ± 0.807
3.229ArgVal: 3.229 ± 0.338
0.745ArgTrp: 0.745 ± 0.517
2.484ArgTyr: 2.484 ± 0.889
0.0ArgXaa: 0.0 ± 0.0
Ser
1.987SerAla: 1.987 ± 1.435
2.484SerCys: 2.484 ± 1.008
1.987SerAsp: 1.987 ± 0.933
4.471SerGlu: 4.471 ± 0.924
2.235SerPhe: 2.235 ± 0.988
2.732SerGly: 2.732 ± 0.425
2.235SerHis: 2.235 ± 0.61
5.216SerIle: 5.216 ± 1.15
3.726SerLys: 3.726 ± 1.554
9.19SerLeu: 9.19 ± 1.153
0.994SerMet: 0.994 ± 0.588
3.726SerAsn: 3.726 ± 0.494
3.477SerPro: 3.477 ± 0.399
3.229SerGln: 3.229 ± 0.995
1.49SerArg: 1.49 ± 0.598
5.216SerSer: 5.216 ± 1.009
7.948SerThr: 7.948 ± 0.963
4.719SerVal: 4.719 ± 0.828
0.994SerTrp: 0.994 ± 0.688
3.726SerTyr: 3.726 ± 0.841
0.0SerXaa: 0.0 ± 0.0
Thr
2.732ThrAla: 2.732 ± 0.671
0.745ThrCys: 0.745 ± 0.502
3.477ThrAsp: 3.477 ± 0.695
5.216ThrGlu: 5.216 ± 1.136
1.49ThrPhe: 1.49 ± 0.449
2.981ThrGly: 2.981 ± 0.739
1.987ThrHis: 1.987 ± 0.456
4.223ThrIle: 4.223 ± 1.207
3.726ThrLys: 3.726 ± 0.677
6.706ThrLeu: 6.706 ± 0.353
2.981ThrMet: 2.981 ± 0.477
5.216ThrAsn: 5.216 ± 0.704
1.739ThrPro: 1.739 ± 0.772
2.981ThrGln: 2.981 ± 1.01
2.981ThrArg: 2.981 ± 0.77
3.229ThrSer: 3.229 ± 0.449
2.484ThrThr: 2.484 ± 0.548
2.981ThrVal: 2.981 ± 1.142
1.987ThrTrp: 1.987 ± 0.931
2.484ThrTyr: 2.484 ± 0.745
0.0ThrXaa: 0.0 ± 0.0
Val
1.987ValAla: 1.987 ± 0.517
1.242ValCys: 1.242 ± 0.303
1.739ValAsp: 1.739 ± 0.68
3.477ValGlu: 3.477 ± 0.761
2.484ValPhe: 2.484 ± 1.139
1.739ValGly: 1.739 ± 0.394
0.745ValHis: 0.745 ± 0.329
4.968ValIle: 4.968 ± 0.871
3.229ValLys: 3.229 ± 0.839
6.21ValLeu: 6.21 ± 1.697
1.739ValMet: 1.739 ± 0.603
2.484ValAsn: 2.484 ± 0.854
0.745ValPro: 0.745 ± 0.301
2.484ValGln: 2.484 ± 1.147
2.484ValArg: 2.484 ± 0.359
3.477ValSer: 3.477 ± 0.977
2.484ValThr: 2.484 ± 0.917
3.477ValVal: 3.477 ± 0.913
0.248ValTrp: 0.248 ± 0.351
2.981ValTyr: 2.981 ± 1.487
0.0ValXaa: 0.0 ± 0.0
Trp
0.497TrpAla: 0.497 ± 0.543
0.497TrpCys: 0.497 ± 0.419
1.739TrpAsp: 1.739 ± 0.965
1.49TrpGlu: 1.49 ± 0.553
0.745TrpPhe: 0.745 ± 0.329
0.497TrpGly: 0.497 ± 0.294
0.248TrpHis: 0.248 ± 0.284
0.248TrpIle: 0.248 ± 0.351
1.242TrpLys: 1.242 ± 0.624
1.739TrpLeu: 1.739 ± 0.551
0.497TrpMet: 0.497 ± 0.742
1.739TrpAsn: 1.739 ± 0.725
0.0TrpPro: 0.0 ± 0.0
0.248TrpGln: 0.248 ± 0.147
0.0TrpArg: 0.0 ± 0.0
0.497TrpSer: 0.497 ± 0.504
0.745TrpThr: 0.745 ± 0.31
0.745TrpVal: 0.745 ± 0.352
0.0TrpTrp: 0.0 ± 0.0
0.994TrpTyr: 0.994 ± 0.333
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.248TyrAla: 0.248 ± 0.147
0.248TyrCys: 0.248 ± 0.147
2.484TyrAsp: 2.484 ± 0.798
1.987TyrGlu: 1.987 ± 0.99
2.235TyrPhe: 2.235 ± 0.767
2.484TyrGly: 2.484 ± 0.909
0.994TyrHis: 0.994 ± 0.424
3.477TyrIle: 3.477 ± 1.079
2.981TyrLys: 2.981 ± 0.475
4.223TyrLeu: 4.223 ± 1.207
0.745TyrMet: 0.745 ± 0.352
4.471TyrAsn: 4.471 ± 1.503
2.732TyrPro: 2.732 ± 0.424
1.242TyrGln: 1.242 ± 0.432
1.242TyrArg: 1.242 ± 0.516
4.223TyrSer: 4.223 ± 0.71
3.974TyrThr: 3.974 ± 1.2
2.484TyrVal: 2.484 ± 0.541
0.248TyrTrp: 0.248 ± 0.445
1.987TyrTyr: 1.987 ± 0.441
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (4027 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski