Amino acid dipepetide frequency for Pusillimonas noertemannii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.239AlaAla: 15.239 ± 0.165	1.265AlaCys: 1.265 ± 0.033	6.098AlaAsp: 6.098 ± 0.068	6.204AlaGlu: 6.204 ± 0.083	3.88AlaPhe: 3.88 ± 0.055	10.49AlaGly: 10.49 ± 0.125	2.49AlaHis: 2.49 ± 0.047	5.444AlaIle: 5.444 ± 0.075	3.305AlaLys: 3.305 ± 0.068	13.451AlaLeu: 13.451 ± 0.132	3.391AlaMet: 3.391 ± 0.057	2.791AlaAsn: 2.791 ± 0.046	5.245AlaPro: 5.245 ± 0.08	5.616AlaGln: 5.616 ± 0.076	8.131AlaArg: 8.131 ± 0.099	6.744AlaSer: 6.744 ± 0.084	5.179AlaThr: 5.179 ± 0.069	8.21AlaVal: 8.21 ± 0.086	1.743AlaTrp: 1.743 ± 0.044	2.783AlaTyr: 2.783 ± 0.05	0.0AlaXaa: 0.0 ± 0.0
Cys	1.033CysAla: 1.033 ± 0.029	0.134CysCys: 0.134 ± 0.01	0.52CysAsp: 0.52 ± 0.02	0.492CysGlu: 0.492 ± 0.016	0.334CysPhe: 0.334 ± 0.015	0.995CysGly: 0.995 ± 0.03	0.256CysHis: 0.256 ± 0.014	0.457CysIle: 0.457 ± 0.019	0.211CysLys: 0.211 ± 0.013	0.925CysLeu: 0.925 ± 0.027	0.214CysMet: 0.214 ± 0.013	0.236CysAsn: 0.236 ± 0.013	0.502CysPro: 0.502 ± 0.025	0.287CysGln: 0.287 ± 0.016	0.587CysArg: 0.587 ± 0.021	0.535CysSer: 0.535 ± 0.022	0.464CysThr: 0.464 ± 0.02	0.751CysVal: 0.751 ± 0.024	0.123CysTrp: 0.123 ± 0.01	0.219CysTyr: 0.219 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	6.388AspAla: 6.388 ± 0.086	0.5AspCys: 0.5 ± 0.023	2.979AspAsp: 2.979 ± 0.053	3.643AspGlu: 3.643 ± 0.058	2.017AspPhe: 2.017 ± 0.04	4.477AspGly: 4.477 ± 0.079	1.177AspHis: 1.177 ± 0.031	2.885AspIle: 2.885 ± 0.046	1.773AspLys: 1.773 ± 0.04	5.146AspLeu: 5.146 ± 0.08	1.407AspMet: 1.407 ± 0.036	1.37AspAsn: 1.37 ± 0.035	3.068AspPro: 3.068 ± 0.047	1.82AspGln: 1.82 ± 0.041	3.192AspArg: 3.192 ± 0.054	2.742AspSer: 2.742 ± 0.059	2.769AspThr: 2.769 ± 0.046	3.931AspVal: 3.931 ± 0.055	0.937AspTrp: 0.937 ± 0.027	1.581AspTyr: 1.581 ± 0.034	0.0AspXaa: 0.0 ± 0.0
Glu	6.686GluAla: 6.686 ± 0.091	0.421GluCys: 0.421 ± 0.018	2.435GluAsp: 2.435 ± 0.051	2.847GluGlu: 2.847 ± 0.06	1.908GluPhe: 1.908 ± 0.041	4.19GluGly: 4.19 ± 0.066	1.558GluHis: 1.558 ± 0.031	2.965GluIle: 2.965 ± 0.058	2.058GluLys: 2.058 ± 0.051	5.875GluLeu: 5.875 ± 0.071	1.276GluMet: 1.276 ± 0.03	1.594GluAsn: 1.594 ± 0.037	2.709GluPro: 2.709 ± 0.052	3.038GluGln: 3.038 ± 0.047	4.297GluArg: 4.297 ± 0.058	2.956GluSer: 2.956 ± 0.049	2.795GluThr: 2.795 ± 0.049	3.773GluVal: 3.773 ± 0.069	0.788GluTrp: 0.788 ± 0.029	1.27GluTyr: 1.27 ± 0.03	0.0GluXaa: 0.0 ± 0.0
Phe	3.637PheAla: 3.637 ± 0.066	0.37PheCys: 0.37 ± 0.019	2.473PheAsp: 2.473 ± 0.045	2.155PheGlu: 2.155 ± 0.036	1.336PhePhe: 1.336 ± 0.037	3.362PheGly: 3.362 ± 0.06	0.769PheHis: 0.769 ± 0.024	1.781PheIle: 1.781 ± 0.044	1.143PheLys: 1.143 ± 0.032	3.173PheLeu: 3.173 ± 0.054	0.91PheMet: 0.91 ± 0.034	1.164PheAsn: 1.164 ± 0.03	1.575PhePro: 1.575 ± 0.033	1.17PheGln: 1.17 ± 0.029	1.938PheArg: 1.938 ± 0.039	2.49PheSer: 2.49 ± 0.048	1.889PheThr: 1.889 ± 0.039	2.712PheVal: 2.712 ± 0.054	0.494PheTrp: 0.494 ± 0.02	1.026PheTyr: 1.026 ± 0.033	0.0PheXaa: 0.0 ± 0.0
Gly	8.785GlyAla: 8.785 ± 0.097	0.855GlyCys: 0.855 ± 0.028	4.001GlyAsp: 4.001 ± 0.073	4.445GlyGlu: 4.445 ± 0.06	3.197GlyPhe: 3.197 ± 0.053	7.465GlyGly: 7.465 ± 0.277	2.065GlyHis: 2.065 ± 0.042	4.438GlyIle: 4.438 ± 0.071	3.513GlyLys: 3.513 ± 0.064	9.194GlyLeu: 9.194 ± 0.102	2.514GlyMet: 2.514 ± 0.047	2.32GlyAsn: 2.32 ± 0.063	3.373GlyPro: 3.373 ± 0.05	3.501GlyGln: 3.501 ± 0.057	5.782GlyArg: 5.782 ± 0.066	5.036GlySer: 5.036 ± 0.099	4.246GlyThr: 4.246 ± 0.073	6.585GlyVal: 6.585 ± 0.08	1.341GlyTrp: 1.341 ± 0.033	2.476GlyTyr: 2.476 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	2.736HisAla: 2.736 ± 0.05	0.289HisCys: 0.289 ± 0.015	1.394HisAsp: 1.394 ± 0.037	1.415HisGlu: 1.415 ± 0.033	0.888HisPhe: 0.888 ± 0.03	2.189HisGly: 2.189 ± 0.044	0.656HisHis: 0.656 ± 0.023	1.091HisIle: 1.091 ± 0.031	0.609HisLys: 0.609 ± 0.021	2.061HisLeu: 2.061 ± 0.048	0.527HisMet: 0.527 ± 0.023	0.625HisAsn: 0.625 ± 0.021	1.446HisPro: 1.446 ± 0.035	0.783HisGln: 0.783 ± 0.022	1.437HisArg: 1.437 ± 0.036	1.254HisSer: 1.254 ± 0.037	1.098HisThr: 1.098 ± 0.033	1.668HisVal: 1.668 ± 0.041	0.403HisTrp: 0.403 ± 0.018	0.725HisTyr: 0.725 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	5.935IleAla: 5.935 ± 0.073	0.449IleCys: 0.449 ± 0.021	3.338IleAsp: 3.338 ± 0.05	3.479IleGlu: 3.479 ± 0.057	1.579IlePhe: 1.579 ± 0.038	4.296IleGly: 4.296 ± 0.072	0.959IleHis: 0.959 ± 0.029	2.077IleIle: 2.077 ± 0.049	1.654IleLys: 1.654 ± 0.04	4.051IleLeu: 4.051 ± 0.072	1.074IleMet: 1.074 ± 0.034	1.516IleAsn: 1.516 ± 0.034	2.289IlePro: 2.289 ± 0.043	1.696IleGln: 1.696 ± 0.039	2.754IleArg: 2.754 ± 0.047	2.956IleSer: 2.956 ± 0.058	2.619IleThr: 2.619 ± 0.048	3.995IleVal: 3.995 ± 0.068	0.604IleTrp: 0.604 ± 0.023	1.201IleTyr: 1.201 ± 0.031	0.0IleXaa: 0.0 ± 0.0
Lys	3.908LysAla: 3.908 ± 0.066	0.148LysCys: 0.148 ± 0.01	1.541LysAsp: 1.541 ± 0.039	1.774LysGlu: 1.774 ± 0.039	0.879LysPhe: 0.879 ± 0.028	2.606LysGly: 2.606 ± 0.05	0.729LysHis: 0.729 ± 0.022	1.501LysIle: 1.501 ± 0.041	1.361LysLys: 1.361 ± 0.054	3.296LysLeu: 3.296 ± 0.055	0.812LysMet: 0.812 ± 0.026	0.964LysAsn: 0.964 ± 0.034	1.949LysPro: 1.949 ± 0.044	1.368LysGln: 1.368 ± 0.036	2.209LysArg: 2.209 ± 0.045	1.755LysSer: 1.755 ± 0.044	1.825LysThr: 1.825 ± 0.047	2.479LysVal: 2.479 ± 0.048	0.441LysTrp: 0.441 ± 0.02	0.73LysTyr: 0.73 ± 0.023	0.0LysXaa: 0.0 ± 0.0
Leu	13.805LeuAla: 13.805 ± 0.146	1.057LeuCys: 1.057 ± 0.028	6.08LeuAsp: 6.08 ± 0.08	5.553LeuGlu: 5.553 ± 0.076	3.71LeuPhe: 3.71 ± 0.067	8.8LeuGly: 8.8 ± 0.098	2.366LeuHis: 2.366 ± 0.047	4.912LeuIle: 4.912 ± 0.081	3.421LeuLys: 3.421 ± 0.057	10.66LeuLeu: 10.66 ± 0.137	2.476LeuMet: 2.476 ± 0.052	2.918LeuAsn: 2.918 ± 0.055	5.748LeuPro: 5.748 ± 0.078	3.903LeuGln: 3.903 ± 0.061	7.359LeuArg: 7.359 ± 0.087	6.457LeuSer: 6.457 ± 0.076	5.009LeuThr: 5.009 ± 0.07	7.358LeuVal: 7.358 ± 0.096	1.245LeuTrp: 1.245 ± 0.035	2.361LeuTyr: 2.361 ± 0.045	0.0LeuXaa: 0.0 ± 0.0
Met	3.169MetAla: 3.169 ± 0.055	0.172MetCys: 0.172 ± 0.011	1.164MetAsp: 1.164 ± 0.029	1.071MetGlu: 1.071 ± 0.031	0.746MetPhe: 0.746 ± 0.026	2.006MetGly: 2.006 ± 0.045	0.61MetHis: 0.61 ± 0.023	1.053MetIle: 1.053 ± 0.029	1.018MetLys: 1.018 ± 0.026	2.917MetLeu: 2.917 ± 0.063	0.625MetMet: 0.625 ± 0.021	0.925MetAsn: 0.925 ± 0.027	1.58MetPro: 1.58 ± 0.033	1.173MetGln: 1.173 ± 0.029	1.811MetArg: 1.811 ± 0.038	1.698MetSer: 1.698 ± 0.04	1.426MetThr: 1.426 ± 0.035	1.687MetVal: 1.687 ± 0.039	0.236MetTrp: 0.236 ± 0.015	0.434MetTyr: 0.434 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.22AsnAla: 3.22 ± 0.06	0.241AsnCys: 0.241 ± 0.015	1.469AsnAsp: 1.469 ± 0.035	1.489AsnGlu: 1.489 ± 0.034	1.004AsnPhe: 1.004 ± 0.033	2.404AsnGly: 2.404 ± 0.059	0.618AsnHis: 0.618 ± 0.024	1.45AsnIle: 1.45 ± 0.031	0.873AsnLys: 0.873 ± 0.027	2.704AsnLeu: 2.704 ± 0.047	0.724AsnMet: 0.724 ± 0.024	0.839AsnAsn: 0.839 ± 0.031	1.844AsnPro: 1.844 ± 0.042	0.979AsnGln: 0.979 ± 0.027	1.748AsnArg: 1.748 ± 0.038	1.388AsnSer: 1.388 ± 0.042	1.617AsnThr: 1.617 ± 0.039	2.103AsnVal: 2.103 ± 0.05	0.452AsnTrp: 0.452 ± 0.02	0.741AsnTyr: 0.741 ± 0.027	0.0AsnXaa: 0.0 ± 0.0
Pro	6.204ProAla: 6.204 ± 0.078	0.377ProCys: 0.377 ± 0.016	3.462ProAsp: 3.462 ± 0.05	3.716ProGlu: 3.716 ± 0.058	1.774ProPhe: 1.774 ± 0.039	4.494ProGly: 4.494 ± 0.057	1.147ProHis: 1.147 ± 0.03	2.143ProIle: 2.143 ± 0.042	1.373ProLys: 1.373 ± 0.038	4.956ProLeu: 4.956 ± 0.072	1.321ProMet: 1.321 ± 0.032	1.361ProAsn: 1.361 ± 0.035	2.52ProPro: 2.52 ± 0.05	1.985ProGln: 1.985 ± 0.038	2.971ProArg: 2.971 ± 0.052	2.984ProSer: 2.984 ± 0.049	2.217ProThr: 2.217 ± 0.038	4.006ProVal: 4.006 ± 0.058	0.793ProTrp: 0.793 ± 0.027	1.27ProTyr: 1.27 ± 0.038	0.0ProXaa: 0.0 ± 0.0
Gln	6.225GlnAla: 6.225 ± 0.093	0.351GlnCys: 0.351 ± 0.016	1.832GlnAsp: 1.832 ± 0.04	2.058GlnGlu: 2.058 ± 0.041	1.235GlnPhe: 1.235 ± 0.033	3.505GlnGly: 3.505 ± 0.052	0.961GlnHis: 0.961 ± 0.027	1.923GlnIle: 1.923 ± 0.04	1.229GlnLys: 1.229 ± 0.028	4.041GlnLeu: 4.041 ± 0.06	0.96GlnMet: 0.96 ± 0.026	1.023GlnAsn: 1.023 ± 0.03	2.117GlnPro: 2.117 ± 0.042	1.888GlnGln: 1.888 ± 0.047	3.154GlnArg: 3.154 ± 0.063	2.179GlnSer: 2.179 ± 0.048	1.826GlnThr: 1.826 ± 0.038	2.893GlnVal: 2.893 ± 0.045	0.696GlnTrp: 0.696 ± 0.022	0.943GlnTyr: 0.943 ± 0.029	0.0GlnXaa: 0.0 ± 0.0
Arg	6.798ArgAla: 6.798 ± 0.097	0.578ArgCys: 0.578 ± 0.021	3.488ArgAsp: 3.488 ± 0.057	3.808ArgGlu: 3.808 ± 0.059	2.682ArgPhe: 2.682 ± 0.046	4.599ArgGly: 4.599 ± 0.064	1.932ArgHis: 1.932 ± 0.041	3.772ArgIle: 3.772 ± 0.06	2.288ArgLys: 2.288 ± 0.048	7.657ArgLeu: 7.657 ± 0.094	1.818ArgMet: 1.818 ± 0.04	2.096ArgAsn: 2.096 ± 0.04	3.268ArgPro: 3.268 ± 0.051	3.173ArgGln: 3.173 ± 0.06	5.174ArgArg: 5.174 ± 0.084	3.801ArgSer: 3.801 ± 0.056	2.944ArgThr: 2.944 ± 0.049	4.641ArgVal: 4.641 ± 0.063	0.97ArgTrp: 0.97 ± 0.033	2.023ArgTyr: 2.023 ± 0.047	0.0ArgXaa: 0.0 ± 0.0
Ser	6.18SerAla: 6.18 ± 0.088	0.494SerCys: 0.494 ± 0.02	2.937SerAsp: 2.937 ± 0.043	2.703SerGlu: 2.703 ± 0.049	2.222SerPhe: 2.222 ± 0.042	5.776SerGly: 5.776 ± 0.083	1.286SerHis: 1.286 ± 0.033	2.993SerIle: 2.993 ± 0.058	1.675SerLys: 1.675 ± 0.036	6.296SerLeu: 6.296 ± 0.079	1.578SerMet: 1.578 ± 0.036	1.599SerAsn: 1.599 ± 0.036	2.995SerPro: 2.995 ± 0.046	2.199SerGln: 2.199 ± 0.041	3.931SerArg: 3.931 ± 0.065	3.628SerSer: 3.628 ± 0.059	3.042SerThr: 3.042 ± 0.059	4.197SerVal: 4.197 ± 0.067	0.873SerTrp: 0.873 ± 0.029	1.546SerTyr: 1.546 ± 0.035	0.0SerXaa: 0.0 ± 0.0
Thr	5.165ThrAla: 5.165 ± 0.073	0.366ThrCys: 0.366 ± 0.019	2.389ThrAsp: 2.389 ± 0.047	2.472ThrGlu: 2.472 ± 0.051	1.714ThrPhe: 1.714 ± 0.037	4.655ThrGly: 4.655 ± 0.067	1.188ThrHis: 1.188 ± 0.029	2.351ThrIle: 2.351 ± 0.048	1.158ThrLys: 1.158 ± 0.031	5.935ThrLeu: 5.935 ± 0.075	1.108ThrMet: 1.108 ± 0.029	1.17ThrAsn: 1.17 ± 0.037	3.275ThrPro: 3.275 ± 0.053	1.91ThrGln: 1.91 ± 0.039	3.087ThrArg: 3.087 ± 0.05	2.734ThrSer: 2.734 ± 0.052	2.551ThrThr: 2.551 ± 0.05	4.119ThrVal: 4.119 ± 0.061	0.617ThrTrp: 0.617 ± 0.023	1.107ThrTyr: 1.107 ± 0.035	0.0ThrXaa: 0.0 ± 0.0
Val	8.547ValAla: 8.547 ± 0.09	0.765ValCys: 0.765 ± 0.025	4.153ValAsp: 4.153 ± 0.061	4.16ValGlu: 4.16 ± 0.059	2.862ValPhe: 2.862 ± 0.053	5.601ValGly: 5.601 ± 0.073	1.597ValHis: 1.597 ± 0.034	3.524ValIle: 3.524 ± 0.061	2.335ValLys: 2.335 ± 0.043	8.287ValLeu: 8.287 ± 0.1	1.815ValMet: 1.815 ± 0.041	2.209ValAsn: 2.209 ± 0.051	3.693ValPro: 3.693 ± 0.057	2.788ValGln: 2.788 ± 0.052	4.886ValArg: 4.886 ± 0.057	4.521ValSer: 4.521 ± 0.076	3.464ValThr: 3.464 ± 0.066	6.0ValVal: 6.0 ± 0.089	0.963ValTrp: 0.963 ± 0.03	1.752ValTyr: 1.752 ± 0.038	0.0ValXaa: 0.0 ± 0.0
Trp	1.3TrpAla: 1.3 ± 0.035	0.148TrpCys: 0.148 ± 0.01	0.593TrpAsp: 0.593 ± 0.02	0.554TrpGlu: 0.554 ± 0.02	0.55TrpPhe: 0.55 ± 0.022	0.921TrpGly: 0.921 ± 0.03	0.388TrpHis: 0.388 ± 0.018	0.683TrpIle: 0.683 ± 0.025	0.517TrpLys: 0.517 ± 0.02	2.023TrpLeu: 2.023 ± 0.049	0.43TrpMet: 0.43 ± 0.017	0.489TrpAsn: 0.489 ± 0.019	0.689TrpPro: 0.689 ± 0.024	0.731TrpGln: 0.731 ± 0.026	1.249TrpArg: 1.249 ± 0.036	0.798TrpSer: 0.798 ± 0.025	0.747TrpThr: 0.747 ± 0.027	0.969TrpVal: 0.969 ± 0.029	0.238TrpTrp: 0.238 ± 0.014	0.355TrpTyr: 0.355 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.742TyrAla: 2.742 ± 0.049	0.294TyrCys: 0.294 ± 0.014	1.456TyrAsp: 1.456 ± 0.039	1.404TyrGlu: 1.404 ± 0.039	1.05TyrPhe: 1.05 ± 0.03	2.3TyrGly: 2.3 ± 0.042	0.541TyrHis: 0.541 ± 0.023	1.076TyrIle: 1.076 ± 0.03	0.76TyrLys: 0.76 ± 0.027	2.553TyrLeu: 2.553 ± 0.043	0.54TyrMet: 0.54 ± 0.021	0.696TyrAsn: 0.696 ± 0.027	1.191TyrPro: 1.191 ± 0.035	1.03TyrGln: 1.03 ± 0.03	1.814TyrArg: 1.814 ± 0.039	1.496TyrSer: 1.496 ± 0.032	1.342TyrThr: 1.342 ± 0.033	1.845TyrVal: 1.845 ± 0.034	0.414TyrTrp: 0.414 ± 0.02	0.68TyrTyr: 0.68 ± 0.024	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3863 proteins (1266444 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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