Echinococcus granulosus (Hydatid tapeworm)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda; Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus;

Average proteome isoelectric point is 7.01

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 11279 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|W6U0T9|W6U0T9_ECHGR Uncharacterized protein OS=Echinococcus granulosus OX=6210 GN=EGR_10476 PE=4 SV=1
MM1 pKa = 7.08KK2 pKa = 9.75TLLFLLTLSAILLVACTKK20 pKa = 10.26ARR22 pKa = 11.84PYY24 pKa = 6.71TTPIATQLRR33 pKa = 11.84DD34 pKa = 3.51EE35 pKa = 4.79RR36 pKa = 11.84GEE38 pKa = 3.96EE39 pKa = 4.2SSGKK43 pKa = 10.17DD44 pKa = 3.07AVSQADD50 pKa = 3.52GHH52 pKa = 7.05DD53 pKa = 3.65EE54 pKa = 3.9QDD56 pKa = 3.51DD57 pKa = 4.05NEE59 pKa = 5.3DD60 pKa = 3.64YY61 pKa = 11.42DD62 pKa = 4.08VFIYY66 pKa = 10.55DD67 pKa = 4.37SYY69 pKa = 11.76NDD71 pKa = 3.83TVKK74 pKa = 11.08ADD76 pKa = 3.53AQEE79 pKa = 4.2VEE81 pKa = 4.28EE82 pKa = 4.47TEE84 pKa = 3.99AAEE87 pKa = 4.71EE88 pKa = 4.01YY89 pKa = 11.02DD90 pKa = 3.19EE91 pKa = 6.3AYY93 pKa = 11.08YY94 pKa = 11.0DD95 pKa = 3.96DD96 pKa = 4.04EE97 pKa = 4.74WYY99 pKa = 10.78AKK101 pKa = 9.28YY102 pKa = 10.86APVYY106 pKa = 11.02VDD108 pKa = 4.69FEE110 pKa = 4.54EE111 pKa = 5.06KK112 pKa = 10.66KK113 pKa = 10.96EE114 pKa = 3.95GDD116 pKa = 3.32KK117 pKa = 11.36DD118 pKa = 4.18KK119 pKa = 11.24EE120 pKa = 4.17DD121 pKa = 3.64EE122 pKa = 4.41RR123 pKa = 11.84EE124 pKa = 4.0GLTFDD129 pKa = 3.78DD130 pKa = 5.07ARR132 pKa = 11.84YY133 pKa = 6.64TQHH136 pKa = 5.58TPAYY140 pKa = 8.83KK141 pKa = 10.27EE142 pKa = 3.97EE143 pKa = 4.2EE144 pKa = 4.25EE145 pKa = 4.66KK146 pKa = 11.3EE147 pKa = 3.98EE148 pKa = 4.07TEE150 pKa = 3.95AAEE153 pKa = 4.78EE154 pKa = 4.01YY155 pKa = 11.02DD156 pKa = 3.19EE157 pKa = 6.3AYY159 pKa = 11.08YY160 pKa = 11.0DD161 pKa = 3.96DD162 pKa = 4.04EE163 pKa = 4.74WYY165 pKa = 10.78AKK167 pKa = 9.15YY168 pKa = 10.81APVYY172 pKa = 9.12VQSDD176 pKa = 3.93EE177 pKa = 4.52NEE179 pKa = 4.07EE180 pKa = 3.99

Molecular weight: 21.06 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|W6UE18|W6UE18_ECHGR Uncharacterized protein OS=Echinococcus granulosus OX=6210 GN=EGR_05894 PE=4 SV=1
MM1 pKa = 7.45ALHH4 pKa = 6.78RR5 pKa = 11.84RR6 pKa = 11.84LHH8 pKa = 6.06PQPQPPMRR16 pKa = 11.84SPPFRR21 pKa = 11.84PSRR24 pKa = 11.84LPPSTFPSALDD35 pKa = 3.56LTLSLALHH43 pKa = 6.53TCTHH47 pKa = 6.76AGRR50 pKa = 11.84RR51 pKa = 11.84ARR53 pKa = 11.84SRR55 pKa = 11.84SHH57 pKa = 4.92NTPRR61 pKa = 11.84LAPFSQHH68 pKa = 5.7VLLLASRR75 pKa = 11.84SLSCAYY81 pKa = 9.77CQQAVATSSQWLSARR96 pKa = 11.84VSAVRR101 pKa = 11.84SCALGRR107 pKa = 11.84LKK109 pKa = 11.03YY110 pKa = 10.2LVPGCAAASLPLLTPFVLPLLLLPLLLVSQTIHH143 pKa = 6.85LSSAQLLVEE152 pKa = 4.73LPFPSPANRR161 pKa = 11.84LFFPCLNPSQSSHH174 pKa = 5.85EE175 pKa = 4.47SVDD178 pKa = 3.73SGCCDD183 pKa = 3.77AEE185 pKa = 4.7GSLNTCSKK193 pKa = 10.53VFNTFSLINTPSQQQQQAPFPSHH216 pKa = 5.24STPPKK221 pKa = 10.14RR222 pKa = 11.84PPLTKK227 pKa = 9.79PRR229 pKa = 11.84SSMKK233 pKa = 10.05KK234 pKa = 10.32DD235 pKa = 3.08EE236 pKa = 4.53TTTPTAKK243 pKa = 10.43AAEE246 pKa = 4.19TAQTGGGASYY256 pKa = 10.76KK257 pKa = 10.14YY258 pKa = 9.31LTWRR262 pKa = 11.84EE263 pKa = 3.08KK264 pKa = 10.4DD265 pKa = 2.74RR266 pKa = 11.84RR267 pKa = 11.84RR268 pKa = 11.84RR269 pKa = 11.84FRR271 pKa = 11.84EE272 pKa = 3.65EE273 pKa = 3.79WKK275 pKa = 10.55HH276 pKa = 5.03LWLVVPHH283 pKa = 6.32GMYY286 pKa = 10.75EE287 pKa = 4.2VMCLVCHH294 pKa = 7.52KK295 pKa = 10.76IMTQRR300 pKa = 11.84KK301 pKa = 7.9LDD303 pKa = 3.76TIKK306 pKa = 10.01RR307 pKa = 11.84HH308 pKa = 5.2TIRR311 pKa = 11.84RR312 pKa = 11.84HH313 pKa = 5.35AEE315 pKa = 3.88LLSMSEE321 pKa = 4.22TEE323 pKa = 4.24RR324 pKa = 11.84QRR326 pKa = 11.84LYY328 pKa = 11.03HH329 pKa = 7.05DD330 pKa = 5.3LVTQYY335 pKa = 10.16FRR337 pKa = 11.84RR338 pKa = 11.84GGDD341 pKa = 3.28FCGEE345 pKa = 4.0SDD347 pKa = 4.16PFCSTSVPRR356 pKa = 11.84LRR358 pKa = 11.84QTGTRR363 pKa = 11.84GSRR366 pKa = 11.84MEE368 pKa = 3.86VAGVRR373 pKa = 11.84RR374 pKa = 11.84HH375 pKa = 6.05SRR377 pKa = 11.84LTDD380 pKa = 3.2VPSPFRR386 pKa = 11.84ARR388 pKa = 11.84MSAPRR393 pKa = 11.84RR394 pKa = 11.84SEE396 pKa = 3.84IDD398 pKa = 3.2THH400 pKa = 6.65PLASSPPSVQTSMSLLPPPPPPPPLPPPLLPTQSDD435 pKa = 3.79TAALLLNRR443 pKa = 4.92

Molecular weight: 49.36 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

11279

0

11279

5264045

30

7853

466.7

52.0

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.378 ± 0.023

2.203 ± 0.015

4.909 ± 0.016

6.099 ± 0.027

4.087 ± 0.018

5.736 ± 0.029

2.548 ± 0.011

4.977 ± 0.015

4.891 ± 0.022

9.893 ± 0.032

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.142 ± 0.01

4.063 ± 0.013

5.703 ± 0.026

3.98 ± 0.017

6.217 ± 0.018

9.09 ± 0.028

5.912 ± 0.016

6.379 ± 0.017

1.112 ± 0.008

2.679 ± 0.013
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski