Amino acid dipepetide frequency for Beihai picorna-like virus 17

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.194AlaAla: 6.194 ± 0.384
0.774AlaCys: 0.774 ± 0.409
3.097AlaAsp: 3.097 ± 0.481
5.807AlaGlu: 5.807 ± 0.179
4.646AlaPhe: 4.646 ± 0.721
2.71AlaGly: 2.71 ± 0.879
1.549AlaHis: 1.549 ± 0.337
4.646AlaIle: 4.646 ± 1.59
6.194AlaLys: 6.194 ± 1.539
4.259AlaLeu: 4.259 ± 1.216
2.71AlaMet: 2.71 ± 0.177
4.646AlaAsn: 4.646 ± 0.144
3.871AlaPro: 3.871 ± 1.421
3.097AlaGln: 3.097 ± 0.675
2.323AlaArg: 2.323 ± 0.65
5.42AlaSer: 5.42 ± 2.914
6.194AlaThr: 6.194 ± 1.927
5.807AlaVal: 5.807 ± 1.335
1.161AlaTrp: 1.161 ± 0.036
3.097AlaTyr: 3.097 ± 0.481
0.0AlaXaa: 0.0 ± 0.0
Cys
0.774CysAla: 0.774 ± 0.746
0.387CysCys: 0.387 ± 0.205
1.549CysAsp: 1.549 ± 0.24
2.323CysGlu: 2.323 ± 1.227
1.161CysPhe: 1.161 ± 0.036
0.387CysGly: 0.387 ± 0.205
0.387CysHis: 0.387 ± 0.205
0.774CysIle: 0.774 ± 0.409
0.387CysLys: 0.387 ± 0.205
1.936CysLeu: 1.936 ± 0.445
0.774CysMet: 0.774 ± 0.409
0.774CysAsn: 0.774 ± 0.409
0.387CysPro: 0.387 ± 0.205
0.774CysGln: 0.774 ± 0.169
0.774CysArg: 0.774 ± 0.169
1.161CysSer: 1.161 ± 0.036
0.774CysThr: 0.774 ± 0.746
0.387CysVal: 0.387 ± 0.373
0.0CysTrp: 0.0 ± 0.0
0.387CysTyr: 0.387 ± 0.205
0.0CysXaa: 0.0 ± 0.0
Asp
4.259AspAla: 4.259 ± 1.672
0.387AspCys: 0.387 ± 0.205
3.871AspAsp: 3.871 ± 0.89
5.033AspGlu: 5.033 ± 0.807
3.484AspPhe: 3.484 ± 0.47
1.549AspGly: 1.549 ± 0.818
0.774AspHis: 0.774 ± 0.409
3.097AspIle: 3.097 ± 0.675
4.259AspLys: 4.259 ± 1.095
4.259AspLeu: 4.259 ± 2.25
1.161AspMet: 1.161 ± 0.614
1.936AspAsn: 1.936 ± 0.71
3.097AspPro: 3.097 ± 1.83
0.774AspGln: 0.774 ± 0.409
0.387AspArg: 0.387 ± 0.373
3.871AspSer: 3.871 ± 0.265
3.871AspThr: 3.871 ± 1.421
3.871AspVal: 3.871 ± 0.312
1.549AspTrp: 1.549 ± 0.915
2.71AspTyr: 2.71 ± 0.276
0.0AspXaa: 0.0 ± 0.0
Glu
2.323GluAla: 2.323 ± 0.65
1.936GluCys: 1.936 ± 1.023
2.71GluAsp: 2.71 ± 0.276
3.871GluGlu: 3.871 ± 1.468
1.936GluPhe: 1.936 ± 0.445
1.549GluGly: 1.549 ± 0.24
2.323GluHis: 2.323 ± 0.65
3.484GluIle: 3.484 ± 0.685
1.936GluLys: 1.936 ± 1.023
5.42GluLeu: 5.42 ± 0.025
3.097GluMet: 3.097 ± 0.675
1.936GluAsn: 1.936 ± 0.445
2.323GluPro: 2.323 ± 1.084
2.323GluGln: 2.323 ± 0.65
2.71GluArg: 2.71 ± 0.854
4.646GluSer: 4.646 ± 0.144
2.71GluThr: 2.71 ± 0.301
5.42GluVal: 5.42 ± 0.603
1.549GluTrp: 1.549 ± 0.818
2.323GluTyr: 2.323 ± 0.072
0.0GluXaa: 0.0 ± 0.0
Phe
4.646PheAla: 4.646 ± 1.012
0.0PheCys: 0.0 ± 0.0
3.484PheAsp: 3.484 ± 1.048
2.323PheGlu: 2.323 ± 1.084
3.484PhePhe: 3.484 ± 0.108
3.484PheGly: 3.484 ± 0.108
1.161PheHis: 1.161 ± 0.036
2.71PheIle: 2.71 ± 1.432
3.097PheLys: 3.097 ± 1.636
3.484PheLeu: 3.484 ± 1.841
0.774PheMet: 0.774 ± 0.409
3.871PheAsn: 3.871 ± 0.265
1.161PhePro: 1.161 ± 0.614
2.71PheGln: 2.71 ± 0.854
1.549PheArg: 1.549 ± 0.337
3.097PheSer: 3.097 ± 2.408
2.71PheThr: 2.71 ± 0.276
0.774PheVal: 0.774 ± 0.169
0.774PheTrp: 0.774 ± 0.169
3.097PheTyr: 3.097 ± 0.675
0.0PheXaa: 0.0 ± 0.0
Gly
3.871GlyAla: 3.871 ± 1.999
0.774GlyCys: 0.774 ± 0.409
1.936GlyAsp: 1.936 ± 0.445
4.259GlyGlu: 4.259 ± 0.517
3.871GlyPhe: 3.871 ± 0.89
2.323GlyGly: 2.323 ± 0.506
1.161GlyHis: 1.161 ± 0.542
2.323GlyIle: 2.323 ± 0.65
2.323GlyLys: 2.323 ± 1.227
3.484GlyLeu: 3.484 ± 0.47
1.936GlyMet: 1.936 ± 1.023
3.484GlyAsn: 3.484 ± 0.47
1.936GlyPro: 1.936 ± 0.133
1.161GlyGln: 1.161 ± 1.12
1.936GlyArg: 1.936 ± 1.288
3.871GlySer: 3.871 ± 0.265
5.807GlyThr: 5.807 ± 1.554
5.033GlyVal: 5.033 ± 0.348
1.549GlyTrp: 1.549 ± 0.337
2.71GlyTyr: 2.71 ± 0.301
0.0GlyXaa: 0.0 ± 0.0
His
2.323HisAla: 2.323 ± 0.072
0.387HisCys: 0.387 ± 0.205
1.161HisAsp: 1.161 ± 0.614
1.161HisGlu: 1.161 ± 0.542
1.161HisPhe: 1.161 ± 0.542
1.936HisGly: 1.936 ± 1.023
0.387HisHis: 0.387 ± 0.205
2.323HisIle: 2.323 ± 1.084
1.549HisLys: 1.549 ± 0.24
0.774HisLeu: 0.774 ± 0.409
0.0HisMet: 0.0 ± 0.0
1.161HisAsn: 1.161 ± 0.542
2.71HisPro: 2.71 ± 0.276
0.387HisGln: 0.387 ± 0.205
1.549HisArg: 1.549 ± 0.24
1.161HisSer: 1.161 ± 0.542
0.774HisThr: 0.774 ± 0.746
2.323HisVal: 2.323 ± 0.65
0.387HisTrp: 0.387 ± 0.205
0.774HisTyr: 0.774 ± 0.169
0.0HisXaa: 0.0 ± 0.0
Ile
7.743IleAla: 7.743 ± 0.047
0.387IleCys: 0.387 ± 0.373
4.259IleAsp: 4.259 ± 0.061
2.323IleGlu: 2.323 ± 0.072
1.936IlePhe: 1.936 ± 0.133
3.871IleGly: 3.871 ± 0.89
0.387IleHis: 0.387 ± 0.373
4.259IleIle: 4.259 ± 1.095
4.259IleLys: 4.259 ± 1.095
2.71IleLeu: 2.71 ± 0.301
1.161IleMet: 1.161 ± 0.542
3.097IleAsn: 3.097 ± 0.675
4.259IlePro: 4.259 ± 0.639
0.774IleGln: 0.774 ± 0.409
3.097IleArg: 3.097 ± 0.481
5.033IleSer: 5.033 ± 0.926
3.871IleThr: 3.871 ± 1.468
3.484IleVal: 3.484 ± 0.47
1.161IleTrp: 1.161 ± 0.542
0.774IleTyr: 0.774 ± 0.169
0.0IleXaa: 0.0 ± 0.0
Lys
3.097LysAla: 3.097 ± 0.097
0.774LysCys: 0.774 ± 0.409
1.161LysAsp: 1.161 ± 0.614
5.033LysGlu: 5.033 ± 2.659
1.161LysPhe: 1.161 ± 0.036
3.097LysGly: 3.097 ± 1.059
3.097LysHis: 3.097 ± 1.059
2.323LysIle: 2.323 ± 0.072
2.323LysLys: 2.323 ± 1.227
6.581LysLeu: 6.581 ± 0.589
1.549LysMet: 1.549 ± 0.24
2.71LysAsn: 2.71 ± 0.854
2.71LysPro: 2.71 ± 0.276
2.323LysGln: 2.323 ± 0.072
3.097LysArg: 3.097 ± 1.059
5.42LysSer: 5.42 ± 2.286
3.097LysThr: 3.097 ± 0.481
3.097LysVal: 3.097 ± 0.481
0.774LysTrp: 0.774 ± 0.409
3.097LysTyr: 3.097 ± 0.481
0.0LysXaa: 0.0 ± 0.0
Leu
5.42LeuAla: 5.42 ± 0.603
1.936LeuCys: 1.936 ± 0.445
3.871LeuAsp: 3.871 ± 0.265
3.484LeuGlu: 3.484 ± 1.263
3.871LeuPhe: 3.871 ± 0.89
5.807LeuGly: 5.807 ± 0.398
3.097LeuHis: 3.097 ± 1.252
3.871LeuIle: 3.871 ± 0.89
5.42LeuLys: 5.42 ± 0.553
4.259LeuLeu: 4.259 ± 1.794
1.936LeuMet: 1.936 ± 0.133
4.646LeuAsn: 4.646 ± 0.144
4.646LeuPro: 4.646 ± 0.434
3.484LeuGln: 3.484 ± 0.108
3.484LeuArg: 3.484 ± 0.685
4.259LeuSer: 4.259 ± 1.095
6.581LeuThr: 6.581 ± 1.145
3.484LeuVal: 3.484 ± 1.263
0.774LeuTrp: 0.774 ± 0.169
1.936LeuTyr: 1.936 ± 0.133
0.0LeuXaa: 0.0 ± 0.0
Met
3.097MetAla: 3.097 ± 1.059
0.387MetCys: 0.387 ± 0.205
0.774MetAsp: 0.774 ± 0.169
0.387MetGlu: 0.387 ± 0.205
1.549MetPhe: 1.549 ± 0.24
1.549MetGly: 1.549 ± 0.24
0.387MetHis: 0.387 ± 0.205
0.774MetIle: 0.774 ± 0.746
1.549MetLys: 1.549 ± 0.818
2.323MetLeu: 2.323 ± 0.65
0.774MetMet: 0.774 ± 0.169
1.549MetAsn: 1.549 ± 0.24
1.161MetPro: 1.161 ± 0.036
0.774MetGln: 0.774 ± 0.169
3.097MetArg: 3.097 ± 0.481
1.549MetSer: 1.549 ± 0.24
1.549MetThr: 1.549 ± 0.337
1.549MetVal: 1.549 ± 0.24
0.387MetTrp: 0.387 ± 0.205
1.161MetTyr: 1.161 ± 0.036
0.0MetXaa: 0.0 ± 0.0
Asn
5.42AsnAla: 5.42 ± 0.553
1.161AsnCys: 1.161 ± 0.036
1.936AsnAsp: 1.936 ± 0.133
1.161AsnGlu: 1.161 ± 0.036
2.71AsnPhe: 2.71 ± 0.854
3.871AsnGly: 3.871 ± 0.312
1.161AsnHis: 1.161 ± 0.036
5.807AsnIle: 5.807 ± 0.757
2.323AsnLys: 2.323 ± 0.072
4.646AsnLeu: 4.646 ± 1.012
1.161AsnMet: 1.161 ± 0.036
1.549AsnAsn: 1.549 ± 0.24
1.549AsnPro: 1.549 ± 0.337
1.161AsnGln: 1.161 ± 0.036
1.549AsnArg: 1.549 ± 0.337
3.097AsnSer: 3.097 ± 1.252
5.033AsnThr: 5.033 ± 0.23
4.259AsnVal: 4.259 ± 2.95
0.387AsnTrp: 0.387 ± 0.205
2.323AsnTyr: 2.323 ± 0.506
0.0AsnXaa: 0.0 ± 0.0
Pro
3.484ProAla: 3.484 ± 1.625
1.161ProCys: 1.161 ± 1.12
1.549ProAsp: 1.549 ± 0.818
2.323ProGlu: 2.323 ± 1.227
3.484ProPhe: 3.484 ± 1.625
2.71ProGly: 2.71 ± 0.879
1.161ProHis: 1.161 ± 0.036
3.097ProIle: 3.097 ± 0.097
2.323ProLys: 2.323 ± 0.65
4.646ProLeu: 4.646 ± 0.144
0.387ProMet: 0.387 ± 0.205
2.71ProAsn: 2.71 ± 0.879
2.71ProPro: 2.71 ± 0.854
3.097ProGln: 3.097 ± 0.675
1.161ProArg: 1.161 ± 0.036
3.097ProSer: 3.097 ± 0.481
3.871ProThr: 3.871 ± 1.999
3.484ProVal: 3.484 ± 1.263
0.387ProTrp: 0.387 ± 0.373
1.161ProTyr: 1.161 ± 1.12
0.0ProXaa: 0.0 ± 0.0
Gln
5.42GlnAla: 5.42 ± 1.758
0.774GlnCys: 0.774 ± 0.169
1.161GlnAsp: 1.161 ± 0.614
3.484GlnGlu: 3.484 ± 0.108
0.774GlnPhe: 0.774 ± 0.169
1.161GlnGly: 1.161 ± 0.542
1.549GlnHis: 1.549 ± 0.24
1.161GlnIle: 1.161 ± 0.036
1.936GlnLys: 1.936 ± 0.445
2.71GlnLeu: 2.71 ± 1.432
1.549GlnMet: 1.549 ± 0.24
1.549GlnAsn: 1.549 ± 0.915
1.549GlnPro: 1.549 ± 0.915
1.549GlnGln: 1.549 ± 0.818
1.936GlnArg: 1.936 ± 0.445
1.936GlnSer: 1.936 ± 0.445
3.484GlnThr: 3.484 ± 0.47
2.71GlnVal: 2.71 ± 1.457
0.774GlnTrp: 0.774 ± 0.409
1.161GlnTyr: 1.161 ± 0.614
0.0GlnXaa: 0.0 ± 0.0
Arg
3.484ArgAla: 3.484 ± 1.263
1.161ArgCys: 1.161 ± 0.614
3.097ArgAsp: 3.097 ± 0.481
1.936ArgGlu: 1.936 ± 0.445
3.097ArgPhe: 3.097 ± 0.675
2.71ArgGly: 2.71 ± 2.035
0.387ArgHis: 0.387 ± 0.205
4.259ArgIle: 4.259 ± 0.639
2.323ArgLys: 2.323 ± 1.227
2.323ArgLeu: 2.323 ± 0.506
1.936ArgMet: 1.936 ± 0.445
1.936ArgAsn: 1.936 ± 1.023
2.323ArgPro: 2.323 ± 0.506
2.71ArgGln: 2.71 ± 0.854
3.871ArgArg: 3.871 ± 2.045
5.42ArgSer: 5.42 ± 0.025
1.161ArgThr: 1.161 ± 0.542
3.097ArgVal: 3.097 ± 1.059
0.387ArgTrp: 0.387 ± 0.373
0.774ArgTyr: 0.774 ± 0.169
0.0ArgXaa: 0.0 ± 0.0
Ser
5.807SerAla: 5.807 ± 0.976
0.774SerCys: 0.774 ± 0.169
3.871SerAsp: 3.871 ± 0.265
3.871SerGlu: 3.871 ± 0.265
3.097SerPhe: 3.097 ± 1.252
2.71SerGly: 2.71 ± 0.879
1.161SerHis: 1.161 ± 0.036
4.646SerIle: 4.646 ± 1.877
6.581SerLys: 6.581 ± 0.589
6.969SerLeu: 6.969 ± 0.793
0.774SerMet: 0.774 ± 0.169
4.646SerAsn: 4.646 ± 0.144
3.097SerPro: 3.097 ± 1.059
4.646SerGln: 4.646 ± 1.59
2.323SerArg: 2.323 ± 0.506
4.646SerSer: 4.646 ± 0.721
5.42SerThr: 5.42 ± 0.603
6.581SerVal: 6.581 ± 0.589
0.774SerTrp: 0.774 ± 0.409
2.323SerTyr: 2.323 ± 0.506
0.0SerXaa: 0.0 ± 0.0
Thr
3.871ThrAla: 3.871 ± 1.421
0.0ThrCys: 0.0 ± 0.0
5.033ThrAsp: 5.033 ± 0.807
3.871ThrGlu: 3.871 ± 1.421
0.774ThrPhe: 0.774 ± 0.409
3.097ThrGly: 3.097 ± 0.097
2.323ThrHis: 2.323 ± 0.506
4.259ThrIle: 4.259 ± 1.794
3.097ThrLys: 3.097 ± 1.059
6.194ThrLeu: 6.194 ± 2.505
1.549ThrMet: 1.549 ± 0.24
2.323ThrAsn: 2.323 ± 1.084
4.259ThrPro: 4.259 ± 0.517
3.484ThrGln: 3.484 ± 0.47
2.71ThrArg: 2.71 ± 0.276
6.194ThrSer: 6.194 ± 0.384
4.646ThrThr: 4.646 ± 2.167
6.194ThrVal: 6.194 ± 1.927
0.387ThrTrp: 0.387 ± 0.205
2.323ThrTyr: 2.323 ± 1.084
0.0ThrXaa: 0.0 ± 0.0
Val
4.259ValAla: 4.259 ± 1.095
2.71ValCys: 2.71 ± 0.276
5.033ValAsp: 5.033 ± 0.807
0.774ValGlu: 0.774 ± 0.409
4.646ValPhe: 4.646 ± 0.144
5.807ValGly: 5.807 ± 0.976
1.161ValHis: 1.161 ± 0.614
3.097ValIle: 3.097 ± 0.481
2.71ValLys: 2.71 ± 0.301
4.646ValLeu: 4.646 ± 0.144
1.936ValMet: 1.936 ± 1.133
3.484ValAsn: 3.484 ± 0.47
2.71ValPro: 2.71 ± 1.457
1.549ValGln: 1.549 ± 0.24
6.581ValArg: 6.581 ± 0.589
6.581ValSer: 6.581 ± 0.011
3.484ValThr: 3.484 ± 0.47
5.42ValVal: 5.42 ± 1.181
0.387ValTrp: 0.387 ± 0.205
2.323ValTyr: 2.323 ± 0.506
0.0ValXaa: 0.0 ± 0.0
Trp
0.774TrpAla: 0.774 ± 0.169
0.0TrpCys: 0.0 ± 0.0
1.549TrpAsp: 1.549 ± 0.24
0.774TrpGlu: 0.774 ± 0.409
0.774TrpPhe: 0.774 ± 0.409
1.936TrpGly: 1.936 ± 0.71
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.387TrpLys: 0.387 ± 0.205
2.323TrpLeu: 2.323 ± 0.65
0.387TrpMet: 0.387 ± 0.205
1.549TrpAsn: 1.549 ± 0.915
0.0TrpPro: 0.0 ± 0.0
0.387TrpGln: 0.387 ± 0.205
0.774TrpArg: 0.774 ± 0.746
1.161TrpSer: 1.161 ± 0.036
0.387TrpThr: 0.387 ± 0.205
0.774TrpVal: 0.774 ± 0.409
0.0TrpTrp: 0.0 ± 0.0
0.387TrpTyr: 0.387 ± 0.373
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.936TyrAla: 1.936 ± 1.288
0.387TyrCys: 0.387 ± 0.373
3.097TyrAsp: 3.097 ± 0.675
2.323TyrGlu: 2.323 ± 0.65
0.774TyrPhe: 0.774 ± 0.169
3.484TyrGly: 3.484 ± 0.47
0.774TyrHis: 0.774 ± 0.746
1.936TyrIle: 1.936 ± 0.445
1.549TyrLys: 1.549 ± 0.337
2.323TyrLeu: 2.323 ± 0.506
0.387TyrMet: 0.387 ± 0.205
2.71TyrAsn: 2.71 ± 0.301
1.549TyrPro: 1.549 ± 0.24
1.161TyrGln: 1.161 ± 0.542
3.484TyrArg: 3.484 ± 0.108
3.097TyrSer: 3.097 ± 0.097
1.161TyrThr: 1.161 ± 0.036
1.936TyrVal: 1.936 ± 0.445
0.774TyrTrp: 0.774 ± 0.169
1.549TyrTyr: 1.549 ± 1.493
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2584 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski