Leishmania infantum
Average proteome isoelectric point is 6.77
Get precalculated fractions of proteins
Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
All
Note: above files contain also dissociation constants (pKa)
Virtual 2D-PAGE plot for 8045 proteins (isoelectric point calculated using IPC2_protein)
Get csv file with sequences according to given criteria:
* You can choose from 21 different methods for calculating isoelectric point
Summary statistics related to proteome-wise predictions
Protein with the lowest isoelectric point:
>tr|A4I2V2|A4I2V2_LEIIN Putative amino acid transporter OS=Leishmania infantum OX=5671 GN=AAT24 PE=4 SV=1
MM1 pKa = 7.48 SGLRR5 pKa = 11.84 QLIISAFFLVMGFLFLILGCTVVRR29 pKa = 11.84 KK30 pKa = 9.99 RR31 pKa = 11.84 NAWPLMSLALYY42 pKa = 10.01 CFAPVPFFLCGRR54 pKa = 11.84 GADD57 pKa = 3.61 SDD59 pKa = 4.64 DD60 pKa = 5.6 FIDD63 pKa = 6.25 FDD65 pKa = 5.76 DD66 pKa = 4.84 EE67 pKa = 4.34 PLDD70 pKa = 3.86 AFSTVGLFMGGVLLISGPGLAVVLYY95 pKa = 7.66 HH96 pKa = 6.36 TSVICGLALFFTLLSGVCFIAAGVSLTVADD126 pKa = 5.15 GGDD129 pKa = 3.64 GDD131 pKa = 5.32 DD132 pKa = 5.38 AADD135 pKa = 4.44 GYY137 pKa = 11.82 NFF139 pKa = 4.0
Molecular weight: 14.73 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 3.776
IPC2_protein 3.872
IPC_protein 3.846
Toseland 3.617
ProMoST 4.062
Dawson 3.884
Bjellqvist 4.037
Wikipedia 3.897
Rodwell 3.681
Grimsley 3.528
Solomon 3.859
Lehninger 3.821
Nozaki 4.012
DTASelect 4.342
Thurlkill 3.706
EMBOSS 3.897
Sillero 3.986
Patrickios 0.54
IPC_peptide 3.859
IPC2_peptide 3.948
IPC2.peptide.svr19 3.849
Protein with the highest isoelectric point:
>tr|Q25302|Q25302_LEIIN Hypothetical_protein_-_conserved OS=Leishmania infantum OX=5671 GN=LINF_350056300 PE=4 SV=1
MM1 pKa = 7.42 TLQHH5 pKa = 6.97 LLAQGARR12 pKa = 11.84 RR13 pKa = 11.84 TPKK16 pKa = 10.2 RR17 pKa = 11.84 QWHH20 pKa = 5.8 PAVPGLMIVAVTVLASFVSGVTAAPPPIMGGKK52 pKa = 8.58 PAVLIEE58 pKa = 4.23 KK59 pKa = 10.36 VVDD62 pKa = 3.32 CTGRR66 pKa = 11.84 DD67 pKa = 3.57 TIPFYY72 pKa = 10.52 TVEE75 pKa = 4.06 QQANTLAFLAEE86 pKa = 4.43 FPYY89 pKa = 10.59 TIAALSKK96 pKa = 9.03 TWVCRR101 pKa = 11.84 NFCEE105 pKa = 4.22 WDD107 pKa = 3.73 GVHH110 pKa = 5.98 CTAEE114 pKa = 4.28 GVEE117 pKa = 4.1 VRR119 pKa = 11.84 LGSRR123 pKa = 11.84 QLVGRR128 pKa = 11.84 LPEE131 pKa = 4.05 VPTAVDD137 pKa = 3.58 VEE139 pKa = 4.48 QVMVTRR145 pKa = 11.84 FAVEE149 pKa = 4.02 GEE151 pKa = 3.88 GDD153 pKa = 4.06 GIKK156 pKa = 10.33 SQLPEE161 pKa = 3.58 SWRR164 pKa = 11.84 KK165 pKa = 9.74 LEE167 pKa = 3.94 QLKK170 pKa = 10.81 SLEE173 pKa = 4.11 LSLDD177 pKa = 3.63 YY178 pKa = 10.7 RR179 pKa = 11.84 SSASKK184 pKa = 10.57 SSEE187 pKa = 3.7 VQNTVRR193 pKa = 11.84 TVRR196 pKa = 11.84 TITGTASRR204 pKa = 11.84 TEE206 pKa = 4.02 LDD208 pKa = 3.02 RR209 pKa = 11.84 CFIPRR214 pKa = 11.84 NAEE217 pKa = 3.97 NVSLYY222 pKa = 9.9 SNRR225 pKa = 11.84 MSGTLPPHH233 pKa = 7.03 LPICNPKK240 pKa = 9.01 MKK242 pKa = 10.4 YY243 pKa = 10.18 LYY245 pKa = 10.27 LHH247 pKa = 6.76 NNTGLEE253 pKa = 4.02 GTIPKK258 pKa = 9.72 EE259 pKa = 3.8 WGSWTSLQIINIEE272 pKa = 4.0 LTNLCGCPPKK282 pKa = 10.48 EE283 pKa = 3.48 WATFNPSVIVLAEE296 pKa = 3.92 DD297 pKa = 5.6 RR298 pKa = 11.84 ITNPDD303 pKa = 3.52 LCKK306 pKa = 10.69 VSCKK310 pKa = 10.28 DD311 pKa = 3.37 SSSSSSSSSRR321 pKa = 11.84 EE322 pKa = 3.97 LEE324 pKa = 4.0 CDD326 pKa = 3.48 GPIPFYY332 pKa = 10.97 TPTQQAHH339 pKa = 4.59 TRR341 pKa = 11.84 NFLEE345 pKa = 4.09 AFKK348 pKa = 10.39 YY349 pKa = 9.32 TITDD353 pKa = 4.16 LQPLWTCTNFCVWEE367 pKa = 4.21 YY368 pKa = 8.94 VHH370 pKa = 6.24 CTPAGVAVEE379 pKa = 4.05 ITGTEE384 pKa = 4.06 FFGSVPEE391 pKa = 4.47 VPADD395 pKa = 3.67 VNPSEE400 pKa = 4.53 VVVSKK405 pKa = 11.28 LDD407 pKa = 3.85 FSHH410 pKa = 6.58 SGWVEE415 pKa = 3.7 GEE417 pKa = 4.47 YY418 pKa = 10.22 PSSWALLTSLQNVSFAYY435 pKa = 9.29 TSMWGTLPSHH445 pKa = 6.82 WSSMSALKK453 pKa = 10.85 YY454 pKa = 10.51 LDD456 pKa = 5.74 LSFTWTDD463 pKa = 3.02 GRR465 pKa = 11.84 FPEE468 pKa = 4.31 SWSRR472 pKa = 11.84 LANLEE477 pKa = 3.91 VLRR480 pKa = 11.84 LVHH483 pKa = 6.15 LTIPDD488 pKa = 3.9 RR489 pKa = 11.84 LPASWSSMSALRR501 pKa = 11.84 EE502 pKa = 3.76 LDD504 pKa = 3.7 LDD506 pKa = 3.93 STSTSGTLPPSWGALKK522 pKa = 10.6 NLEE525 pKa = 4.39 KK526 pKa = 10.95 LSLSNNNIDD535 pKa = 5.06 AILPAEE541 pKa = 4.14 WSSLTRR547 pKa = 11.84 LRR549 pKa = 11.84 ILHH552 pKa = 6.27 LHH554 pKa = 6.44 HH555 pKa = 6.6 NQLSGSIPEE564 pKa = 4.81 IYY566 pKa = 10.51 NAMSTLTRR574 pKa = 11.84 VSLEE578 pKa = 3.5 INRR581 pKa = 11.84 FCGCLPSTWAAKK593 pKa = 10.36 NGVSMTITAQTEE605 pKa = 4.14 LLAPACATEE614 pKa = 4.26 NACKK618 pKa = 10.28 PEE620 pKa = 4.22 TEE622 pKa = 4.7 FSSSSAPSASSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSVSSSSAPSSSSSAPSASSSSAPSSSSSVPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSTPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSTPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSPSSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSSSSSAPSPSSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSSSSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAPSASSSSAPSSSSSAHH1812 pKa = 4.72 VGGRR1816 pKa = 11.84 RR1817 pKa = 11.84 SIMRR1821 pKa = 11.84 PSRR1824 pKa = 11.84 QQLRR1828 pKa = 11.84 AVGVLVVCAVQQQLRR1843 pKa = 11.84 RR1844 pKa = 11.84 RR1845 pKa = 11.84 QRR1847 pKa = 11.84 PRR1849 pKa = 11.84 RR1850 pKa = 11.84 LRR1852 pKa = 11.84 RR1853 pKa = 11.84 PAAAPRR1859 pKa = 11.84 RR1860 pKa = 11.84 RR1861 pKa = 11.84 RR1862 pKa = 11.84 RR1863 pKa = 11.84 RR1864 pKa = 11.84 RR1865 pKa = 11.84 LRR1867 pKa = 11.84 RR1868 pKa = 11.84 PAAAPRR1874 pKa = 11.84 RR1875 pKa = 11.84 QRR1877 pKa = 11.84 RR1878 pKa = 11.84 RR1879 pKa = 11.84 RR1880 pKa = 11.84 LRR1882 pKa = 11.84 RR1883 pKa = 11.84 PAAAPRR1889 pKa = 11.84 RR1890 pKa = 11.84 QRR1892 pKa = 11.84 RR1893 pKa = 11.84 RR1894 pKa = 11.84 RR1895 pKa = 11.84 LHH1897 pKa = 6.42 RR1898 pKa = 11.84 PAAAPRR1904 pKa = 11.84 RR1905 pKa = 11.84 RR1906 pKa = 11.84 RR1907 pKa = 11.84 HH1908 pKa = 5.01 RR1909 pKa = 11.84 RR1910 pKa = 11.84 LRR1912 pKa = 11.84 RR1913 pKa = 11.84 PAAAPRR1919 pKa = 11.84 RR1920 pKa = 11.84 RR1921 pKa = 11.84 RR1922 pKa = 11.84 RR1923 pKa = 11.84 RR1924 pKa = 11.84 RR1925 pKa = 11.84 LRR1927 pKa = 11.84 RR1928 pKa = 11.84 PAAAPRR1934 pKa = 11.84 RR1935 pKa = 11.84 RR1936 pKa = 11.84 RR1937 pKa = 11.84 PRR1939 pKa = 11.84 RR1940 pKa = 11.84 LRR1942 pKa = 11.84 RR1943 pKa = 11.84 PAAAPRR1949 pKa = 11.84 RR1950 pKa = 11.84 QRR1952 pKa = 11.84 RR1953 pKa = 11.84 RR1954 pKa = 11.84 RR1955 pKa = 11.84 LRR1957 pKa = 11.84 RR1958 pKa = 11.84 PAAAPRR1964 pKa = 11.84 RR1965 pKa = 11.84 RR1966 pKa = 11.84 RR1967 pKa = 11.84 RR1968 pKa = 11.84 RR1969 pKa = 11.84 RR1970 pKa = 11.84 LRR1972 pKa = 11.84 RR1973 pKa = 11.84 PAAAPRR1979 pKa = 11.84 RR1980 pKa = 11.84 RR1981 pKa = 11.84 RR1982 pKa = 11.84 PRR1984 pKa = 11.84 RR1985 pKa = 11.84 LRR1987 pKa = 11.84 RR1988 pKa = 11.84 PAAAPRR1994 pKa = 11.84 RR1995 pKa = 11.84 RR1996 pKa = 11.84 RR1997 pKa = 11.84 RR1998 pKa = 11.84 RR1999 pKa = 11.84 RR2000 pKa = 11.84 LRR2002 pKa = 11.84 RR2003 pKa = 11.84 PAAAPRR2009 pKa = 11.84 RR2010 pKa = 11.84 RR2011 pKa = 11.84 RR2012 pKa = 11.84 PRR2014 pKa = 11.84 RR2015 pKa = 11.84 LRR2017 pKa = 11.84 RR2018 pKa = 11.84 PAAAPRR2024 pKa = 11.84 RR2025 pKa = 11.84 RR2026 pKa = 11.84 RR2027 pKa = 11.84 PRR2029 pKa = 11.84 RR2030 pKa = 11.84 LRR2032 pKa = 11.84 RR2033 pKa = 11.84 PAAAPRR2039 pKa = 11.84 RR2040 pKa = 11.84 RR2041 pKa = 11.84 RR2042 pKa = 11.84 RR2043 pKa = 11.84 RR2044 pKa = 11.84 RR2045 pKa = 11.84 LRR2047 pKa = 11.84 RR2048 pKa = 11.84 PAAAPRR2054 pKa = 11.84 RR2055 pKa = 11.84 RR2056 pKa = 11.84 RR2057 pKa = 11.84 PRR2059 pKa = 11.84 RR2060 pKa = 11.84 LRR2062 pKa = 11.84 RR2063 pKa = 11.84 PAAAPRR2069 pKa = 11.84 RR2070 pKa = 11.84 RR2071 pKa = 11.84 RR2072 pKa = 11.84 RR2073 pKa = 11.84 RR2074 pKa = 11.84 RR2075 pKa = 11.84 LRR2077 pKa = 11.84 RR2078 pKa = 11.84 PAAAPRR2084 pKa = 11.84 RR2085 pKa = 11.84 RR2086 pKa = 11.84 RR2087 pKa = 11.84 PRR2089 pKa = 11.84 RR2090 pKa = 11.84 LRR2092 pKa = 11.84 RR2093 pKa = 11.84 PAAAPRR2099 pKa = 11.84 RR2100 pKa = 11.84 RR2101 pKa = 11.84 RR2102 pKa = 11.84 PRR2104 pKa = 11.84 RR2105 pKa = 11.84 LRR2107 pKa = 11.84 RR2108 pKa = 11.84 PAAAPRR2114 pKa = 11.84 RR2115 pKa = 11.84 RR2116 pKa = 11.84 RR2117 pKa = 11.84 RR2118 pKa = 11.84 RR2119 pKa = 11.84 RR2120 pKa = 11.84 LRR2122 pKa = 11.84 RR2123 pKa = 11.84 PAAAPRR2129 pKa = 11.84 RR2130 pKa = 11.84 RR2131 pKa = 11.84 RR2132 pKa = 11.84 PRR2134 pKa = 11.84 RR2135 pKa = 11.84 LRR2137 pKa = 11.84 RR2138 pKa = 11.84 PAAAPRR2144 pKa = 11.84 RR2145 pKa = 11.84 RR2146 pKa = 11.84 RR2147 pKa = 11.84 PRR2149 pKa = 11.84 RR2150 pKa = 11.84 LRR2152 pKa = 11.84 RR2153 pKa = 11.84 PAAAPRR2159 pKa = 11.84 RR2160 pKa = 11.84 RR2161 pKa = 11.84 RR2162 pKa = 11.84 PRR2164 pKa = 11.84 RR2165 pKa = 11.84 LRR2167 pKa = 11.84 RR2168 pKa = 11.84 PAAAPRR2174 pKa = 11.84 RR2175 pKa = 11.84 RR2176 pKa = 11.84 RR2177 pKa = 11.84 PRR2179 pKa = 11.84 RR2180 pKa = 11.84 LRR2182 pKa = 11.84 RR2183 pKa = 11.84 PAAAPRR2189 pKa = 11.84 RR2190 pKa = 11.84 RR2191 pKa = 11.84 RR2192 pKa = 11.84 PRR2194 pKa = 11.84 RR2195 pKa = 11.84 LRR2197 pKa = 11.84 RR2198 pKa = 11.84 PAAAPRR2204 pKa = 11.84 RR2205 pKa = 11.84 RR2206 pKa = 11.84 RR2207 pKa = 11.84 RR2208 pKa = 11.84 RR2209 pKa = 11.84 RR2210 pKa = 11.84 LRR2212 pKa = 11.84 RR2213 pKa = 11.84 PAAAPRR2219 pKa = 11.84 RR2220 pKa = 11.84 RR2221 pKa = 11.84 RR2222 pKa = 11.84 RR2223 pKa = 11.84 RR2224 pKa = 11.84 RR2225 pKa = 11.84 LRR2227 pKa = 11.84 RR2228 pKa = 11.84 PAAAPRR2234 pKa = 11.84 RR2235 pKa = 11.84 RR2236 pKa = 11.84 RR2237 pKa = 11.84 RR2238 pKa = 11.84 RR2239 pKa = 11.84 RR2240 pKa = 11.84 LRR2242 pKa = 11.84 RR2243 pKa = 11.84 PAAAPRR2249 pKa = 11.84 RR2250 pKa = 11.84 RR2251 pKa = 11.84 RR2252 pKa = 11.84 PRR2254 pKa = 11.84 RR2255 pKa = 11.84 LRR2257 pKa = 11.84 RR2258 pKa = 11.84 PAAALRR2264 pKa = 11.84 RR2265 pKa = 11.84 RR2266 pKa = 11.84 RR2267 pKa = 11.84 RR2268 pKa = 11.84 RR2269 pKa = 11.84 RR2270 pKa = 11.84 LRR2272 pKa = 11.84 RR2273 pKa = 11.84 PAAAPRR2279 pKa = 11.84 RR2280 pKa = 11.84 RR2281 pKa = 11.84 RR2282 pKa = 11.84 RR2283 pKa = 11.84 RR2284 pKa = 11.84 RR2285 pKa = 11.84 LRR2287 pKa = 11.84 RR2288 pKa = 11.84 PAAALRR2294 pKa = 11.84 RR2295 pKa = 11.84 RR2296 pKa = 11.84 RR2297 pKa = 11.84 PRR2299 pKa = 11.84 RR2300 pKa = 11.84 LRR2302 pKa = 11.84 RR2303 pKa = 11.84 PAAAPRR2309 pKa = 11.84 RR2310 pKa = 11.84 RR2311 pKa = 11.84 RR2312 pKa = 11.84 RR2313 pKa = 11.84 RR2314 pKa = 11.84 RR2315 pKa = 11.84 LRR2317 pKa = 11.84 RR2318 pKa = 11.84 PAAAPRR2324 pKa = 11.84 RR2325 pKa = 11.84 PAAAPRR2331 pKa = 11.84 RR2332 pKa = 11.84 RR2333 pKa = 11.84 RR2334 pKa = 11.84 PRR2336 pKa = 11.84 RR2337 pKa = 11.84 LRR2339 pKa = 11.84 RR2340 pKa = 11.84 PAAAPRR2346 pKa = 11.84 RR2347 pKa = 11.84 QRR2349 pKa = 11.84 RR2350 pKa = 11.84 RR2351 pKa = 11.84 RR2352 pKa = 11.84 LRR2354 pKa = 11.84 RR2355 pKa = 11.84 PAAAPRR2361 pKa = 11.84 RR2362 pKa = 11.84 QRR2364 pKa = 11.84 RR2365 pKa = 11.84 RR2366 pKa = 11.84 RR2367 pKa = 11.84 LRR2369 pKa = 11.84 RR2370 pKa = 11.84 PAAAPRR2376 pKa = 11.84 RR2377 pKa = 11.84 RR2378 pKa = 11.84 RR2379 pKa = 11.84 PRR2381 pKa = 11.84 RR2382 pKa = 11.84 LRR2384 pKa = 11.84 RR2385 pKa = 11.84 PAAAPRR2391 pKa = 11.84 RR2392 pKa = 11.84 RR2393 pKa = 11.84 RR2394 pKa = 11.84 PRR2396 pKa = 11.84 RR2397 pKa = 11.84 LRR2399 pKa = 11.84 RR2400 pKa = 11.84 PAAAPRR2406 pKa = 11.84 RR2407 pKa = 11.84 RR2408 pKa = 11.84 RR2409 pKa = 11.84 RR2410 pKa = 11.84 RR2411 pKa = 11.84 RR2412 pKa = 11.84 LRR2414 pKa = 11.84 RR2415 pKa = 11.84 PAAAPRR2421 pKa = 11.84 RR2422 pKa = 11.84 RR2423 pKa = 11.84 RR2424 pKa = 11.84 PRR2426 pKa = 11.84 RR2427 pKa = 11.84 LRR2429 pKa = 11.84 RR2430 pKa = 11.84 PAAAPRR2436 pKa = 11.84 RR2437 pKa = 11.84 RR2438 pKa = 11.84 RR2439 pKa = 11.84 PRR2441 pKa = 11.84 RR2442 pKa = 11.84 LRR2444 pKa = 11.84 RR2445 pKa = 11.84 PAAAPRR2451 pKa = 11.84 RR2452 pKa = 11.84 RR2453 pKa = 11.84 RR2454 pKa = 11.84 RR2455 pKa = 11.84 RR2456 pKa = 11.84 RR2457 pKa = 11.84 LRR2459 pKa = 11.84 RR2460 pKa = 11.84 PAAAPRR2466 pKa = 11.84 RR2467 pKa = 11.84 RR2468 pKa = 11.84 RR2469 pKa = 11.84 RR2470 pKa = 11.84 RR2471 pKa = 11.84 RR2472 pKa = 11.84 LRR2474 pKa = 11.84 RR2475 pKa = 11.84 PAAAPRR2481 pKa = 11.84 RR2482 pKa = 11.84 RR2483 pKa = 11.84 RR2484 pKa = 11.84 RR2485 pKa = 11.84 RR2486 pKa = 11.84 RR2487 pKa = 11.84 LRR2489 pKa = 11.84 RR2490 pKa = 11.84 QQRR2493 pKa = 11.84 PRR2495 pKa = 11.84 RR2496 pKa = 11.84 LRR2498 pKa = 11.84 RR2499 pKa = 11.84 PAAAPRR2505 pKa = 11.84 SSVLAVCAVHH2515 pKa = 6.8 SSPRR2519 pKa = 11.84 RR2520 pKa = 11.84 PAAAPRR2526 pKa = 11.84 RR2527 pKa = 11.84 RR2528 pKa = 11.84 RR2529 pKa = 11.84 RR2530 pKa = 11.84 RR2531 pKa = 11.84 RR2532 pKa = 11.84 LRR2534 pKa = 11.84 RR2535 pKa = 11.84 PAAALRR2541 pKa = 11.84 RR2542 pKa = 11.84 RR2543 pKa = 11.84 RR2544 pKa = 11.84 RR2545 pKa = 11.84 RR2546 pKa = 11.84 RR2547 pKa = 11.84 LRR2549 pKa = 11.84 RR2550 pKa = 11.84 PAAAPRR2556 pKa = 11.84 RR2557 pKa = 11.84 RR2558 pKa = 11.84 RR2559 pKa = 11.84 RR2560 pKa = 11.84 RR2561 pKa = 11.84 RR2562 pKa = 11.84 LRR2564 pKa = 11.84 RR2565 pKa = 11.84 PAAALRR2571 pKa = 11.84 RR2572 pKa = 11.84 RR2573 pKa = 11.84 RR2574 pKa = 11.84 PRR2576 pKa = 11.84 RR2577 pKa = 11.84 LRR2579 pKa = 11.84 RR2580 pKa = 11.84 PAAAPRR2586 pKa = 11.84 RR2587 pKa = 11.84 RR2588 pKa = 11.84 RR2589 pKa = 11.84 RR2590 pKa = 11.84 RR2591 pKa = 11.84 RR2592 pKa = 11.84 LRR2594 pKa = 11.84 RR2595 pKa = 11.84 PAAAPRR2601 pKa = 11.84 RR2602 pKa = 11.84 RR2603 pKa = 11.84 RR2604 pKa = 11.84 RR2605 pKa = 11.84 RR2606 pKa = 11.84 RR2607 pKa = 11.84 LRR2609 pKa = 11.84 RR2610 pKa = 11.84 PAAALRR2616 pKa = 11.84 RR2617 pKa = 11.84 PAAAPRR2623 pKa = 11.84 HH2624 pKa = 4.96 RR2625 pKa = 11.84 RR2626 pKa = 11.84 RR2627 pKa = 11.84 RR2628 pKa = 11.84 RR2629 pKa = 11.84 LRR2631 pKa = 11.84 RR2632 pKa = 11.84 PAAAPRR2638 pKa = 11.84 RR2639 pKa = 11.84 RR2640 pKa = 11.84 RR2641 pKa = 11.84 RR2642 pKa = 11.84 RR2643 pKa = 11.84 RR2644 pKa = 11.84 LRR2646 pKa = 11.84 RR2647 pKa = 11.84 PAAAPRR2653 pKa = 11.84 RR2654 pKa = 11.84 RR2655 pKa = 11.84 RR2656 pKa = 11.84 RR2657 pKa = 11.84 RR2658 pKa = 11.84 RR2659 pKa = 11.84 LRR2661 pKa = 11.84 RR2662 pKa = 11.84 PAAAPRR2668 pKa = 11.84 RR2669 pKa = 11.84 RR2670 pKa = 11.84 RR2671 pKa = 11.84 RR2672 pKa = 11.84 RR2673 pKa = 11.84 RR2674 pKa = 11.84 LRR2676 pKa = 11.84 RR2677 pKa = 11.84 PAAAPRR2683 pKa = 11.84 RR2684 pKa = 11.84 RR2685 pKa = 11.84 RR2686 pKa = 11.84 RR2687 pKa = 11.84 RR2688 pKa = 11.84 RR2689 pKa = 11.84 LRR2691 pKa = 11.84 RR2692 pKa = 11.84 PAAAPRR2698 pKa = 11.84 RR2699 pKa = 11.84 RR2700 pKa = 11.84 RR2701 pKa = 11.84 PRR2703 pKa = 11.84 RR2704 pKa = 11.84 LRR2706 pKa = 11.84 RR2707 pKa = 11.84 PAAAPRR2713 pKa = 11.84 RR2714 pKa = 11.84 QRR2716 pKa = 11.84 PRR2718 pKa = 11.84 RR2719 pKa = 11.84 LRR2721 pKa = 11.84 RR2722 pKa = 11.84 PAAAPRR2728 pKa = 11.84 HH2729 pKa = 5.42 LRR2731 pKa = 11.84 RR2732 pKa = 11.84 LHH2734 pKa = 6.47 RR2735 pKa = 11.84 PAAAPRR2741 pKa = 11.84 RR2742 pKa = 11.84 RR2743 pKa = 11.84 RR2744 pKa = 11.84 RR2745 pKa = 11.84 RR2746 pKa = 11.84 RR2747 pKa = 11.84 LRR2749 pKa = 11.84 RR2750 pKa = 11.84 PAAAPRR2756 pKa = 11.84 RR2757 pKa = 11.84 RR2758 pKa = 11.84 RR2759 pKa = 11.84 PRR2761 pKa = 11.84 RR2762 pKa = 11.84 LRR2764 pKa = 11.84 RR2765 pKa = 11.84 PAAAPRR2771 pKa = 11.84 RR2772 pKa = 11.84 QRR2774 pKa = 11.84 PRR2776 pKa = 11.84 RR2777 pKa = 11.84 LRR2779 pKa = 11.84 RR2780 pKa = 11.84 PAAAPRR2786 pKa = 11.84 RR2787 pKa = 11.84 RR2788 pKa = 11.84 RR2789 pKa = 11.84 PRR2791 pKa = 11.84 RR2792 pKa = 11.84 LRR2794 pKa = 11.84 RR2795 pKa = 11.84 PAAAPRR2801 pKa = 11.84 RR2802 pKa = 11.84 RR2803 pKa = 11.84 RR2804 pKa = 11.84 PRR2806 pKa = 11.84 RR2807 pKa = 11.84 LRR2809 pKa = 11.84 RR2810 pKa = 11.84 PAAAPRR2816 pKa = 11.84 RR2817 pKa = 11.84 QRR2819 pKa = 11.84 PRR2821 pKa = 11.84 RR2822 pKa = 11.84 LRR2824 pKa = 11.84 RR2825 pKa = 11.84 PAAAPRR2831 pKa = 11.84 RR2832 pKa = 11.84 QRR2834 pKa = 11.84 PRR2836 pKa = 11.84 RR2837 pKa = 11.84 LHH2839 pKa = 6.4 RR2840 pKa = 11.84 PAAAPRR2846 pKa = 11.84 HH2847 pKa = 5.42 LRR2849 pKa = 11.84 RR2850 pKa = 11.84 LHH2852 pKa = 6.47 RR2853 pKa = 11.84 PAAAPRR2859 pKa = 11.84 RR2860 pKa = 11.84 RR2861 pKa = 11.84 RR2862 pKa = 11.84 RR2863 pKa = 11.84 RR2864 pKa = 11.84 RR2865 pKa = 11.84 LRR2867 pKa = 11.84 RR2868 pKa = 11.84 PAAAPRR2874 pKa = 11.84 RR2875 pKa = 11.84 RR2876 pKa = 11.84 RR2877 pKa = 11.84 PRR2879 pKa = 11.84 RR2880 pKa = 11.84 LRR2882 pKa = 11.84 RR2883 pKa = 11.84 PAAAPRR2889 pKa = 11.84 RR2890 pKa = 11.84 RR2891 pKa = 11.84 RR2892 pKa = 11.84 RR2893 pKa = 11.84 RR2894 pKa = 11.84 RR2895 pKa = 11.84 LRR2897 pKa = 11.84 RR2898 pKa = 11.84 PAAAPRR2904 pKa = 11.84 RR2905 pKa = 11.84 RR2906 pKa = 11.84 RR2907 pKa = 11.84 PRR2909 pKa = 11.84 RR2910 pKa = 11.84 LRR2912 pKa = 11.84 RR2913 pKa = 11.84 PAAAPRR2919 pKa = 11.84 RR2920 pKa = 11.84 RR2921 pKa = 11.84 RR2922 pKa = 11.84 PRR2924 pKa = 11.84 RR2925 pKa = 11.84 LRR2927 pKa = 11.84 RR2928 pKa = 11.84 PAAAPRR2934 pKa = 11.84 RR2935 pKa = 11.84 RR2936 pKa = 11.84 RR2937 pKa = 11.84 RR2938 pKa = 11.84 RR2939 pKa = 11.84 RR2940 pKa = 11.84 LRR2942 pKa = 11.84 RR2943 pKa = 11.84 PAAAPRR2949 pKa = 11.84 RR2950 pKa = 11.84 RR2951 pKa = 11.84 RR2952 pKa = 11.84 PRR2954 pKa = 11.84 RR2955 pKa = 11.84 LRR2957 pKa = 11.84 RR2958 pKa = 11.84 PAAAPRR2964 pKa = 11.84 RR2965 pKa = 11.84 RR2966 pKa = 11.84 RR2967 pKa = 11.84 PRR2969 pKa = 11.84 RR2970 pKa = 11.84 LRR2972 pKa = 11.84 RR2973 pKa = 11.84 PAAAPHH2979 pKa = 6.0 RR2980 pKa = 11.84 RR2981 pKa = 11.84 RR2982 pKa = 11.84 PRR2984 pKa = 11.84 RR2985 pKa = 11.84 LRR2987 pKa = 11.84 RR2988 pKa = 11.84 PAAAPRR2994 pKa = 11.84 RR2995 pKa = 11.84 RR2996 pKa = 11.84 RR2997 pKa = 11.84 PRR2999 pKa = 11.84 RR3000 pKa = 11.84 LRR3002 pKa = 11.84 RR3003 pKa = 11.84 PAAAPRR3009 pKa = 11.84 RR3010 pKa = 11.84 RR3011 pKa = 11.84 RR3012 pKa = 11.84 RR3013 pKa = 11.84 RR3014 pKa = 11.84 LRR3016 pKa = 11.84 RR3017 pKa = 11.84 PAAAPRR3023 pKa = 11.84 RR3024 pKa = 11.84 RR3025 pKa = 11.84 RR3026 pKa = 11.84 RR3027 pKa = 11.84 RR3028 pKa = 11.84 RR3029 pKa = 11.84 LHH3031 pKa = 6.46 RR3032 pKa = 11.84 PAAAPRR3038 pKa = 11.84 RR3039 pKa = 11.84 RR3040 pKa = 11.84 RR3041 pKa = 11.84 PRR3043 pKa = 11.84 RR3044 pKa = 11.84 LHH3046 pKa = 6.45 RR3047 pKa = 11.84 PAAAPRR3053 pKa = 11.84 RR3054 pKa = 11.84 RR3055 pKa = 11.84 RR3056 pKa = 11.84 RR3057 pKa = 11.84 RR3058 pKa = 11.84 RR3059 pKa = 11.84 LHH3061 pKa = 6.46 RR3062 pKa = 11.84 PAAAPRR3068 pKa = 11.84 RR3069 pKa = 11.84 RR3070 pKa = 11.84 RR3071 pKa = 11.84 PRR3073 pKa = 11.84 RR3074 pKa = 11.84 LRR3076 pKa = 11.84 RR3077 pKa = 11.84 PAAAPRR3083 pKa = 11.84 RR3084 pKa = 11.84 RR3085 pKa = 11.84 RR3086 pKa = 11.84 RR3087 pKa = 11.84 RR3088 pKa = 11.84 RR3089 pKa = 11.84 LRR3091 pKa = 11.84 RR3092 pKa = 11.84 PAAAPRR3098 pKa = 11.84 RR3099 pKa = 11.84 RR3100 pKa = 11.84 RR3101 pKa = 11.84 PRR3103 pKa = 11.84 RR3104 pKa = 11.84 LRR3106 pKa = 11.84 RR3107 pKa = 11.84 PAAAPRR3113 pKa = 11.84 RR3114 pKa = 11.84 RR3115 pKa = 11.84 RR3116 pKa = 11.84 RR3117 pKa = 11.84 RR3118 pKa = 11.84 RR3119 pKa = 11.84 LRR3121 pKa = 11.84 RR3122 pKa = 11.84 PAAAPRR3128 pKa = 11.84 RR3129 pKa = 11.84 RR3130 pKa = 11.84 RR3131 pKa = 11.84 RR3132 pKa = 11.84 RR3133 pKa = 11.84 RR3134 pKa = 11.84 LRR3136 pKa = 11.84 RR3137 pKa = 11.84 PAAAPRR3143 pKa = 11.84 RR3144 pKa = 11.84 RR3145 pKa = 11.84 RR3146 pKa = 11.84 PRR3148 pKa = 11.84 RR3149 pKa = 11.84 LRR3151 pKa = 11.84 RR3152 pKa = 11.84 PAAAPRR3158 pKa = 11.84 RR3159 pKa = 11.84 RR3160 pKa = 11.84 RR3161 pKa = 11.84 RR3162 pKa = 11.84 RR3163 pKa = 11.84 RR3164 pKa = 11.84 LRR3166 pKa = 11.84 RR3167 pKa = 11.84 PAAAPRR3173 pKa = 11.84 RR3174 pKa = 11.84 RR3175 pKa = 11.84 RR3176 pKa = 11.84 PRR3178 pKa = 11.84 RR3179 pKa = 11.84 LRR3181 pKa = 11.84 RR3182 pKa = 11.84 PAAAPRR3188 pKa = 11.84 RR3189 pKa = 11.84 RR3190 pKa = 11.84 RR3191 pKa = 11.84 PRR3193 pKa = 11.84 RR3194 pKa = 11.84 LRR3196 pKa = 11.84 RR3197 pKa = 11.84 PAAAPRR3203 pKa = 11.84 RR3204 pKa = 11.84 RR3205 pKa = 11.84 RR3206 pKa = 11.84 RR3207 pKa = 11.84 RR3208 pKa = 11.84 RR3209 pKa = 11.84 LRR3211 pKa = 11.84 RR3212 pKa = 11.84 PAAAPRR3218 pKa = 11.84 RR3219 pKa = 11.84 RR3220 pKa = 11.84 RR3221 pKa = 11.84 RR3222 pKa = 11.84 RR3223 pKa = 11.84 RR3224 pKa = 11.84 LRR3226 pKa = 11.84 RR3227 pKa = 11.84 PAAAPRR3233 pKa = 11.84 RR3234 pKa = 11.84 RR3235 pKa = 11.84 RR3236 pKa = 11.84 PRR3238 pKa = 11.84 RR3239 pKa = 11.84 LRR3241 pKa = 11.84 RR3242 pKa = 11.84 PAAAPRR3248 pKa = 11.84 RR3249 pKa = 11.84 RR3250 pKa = 11.84 RR3251 pKa = 11.84 RR3252 pKa = 11.84 RR3253 pKa = 11.84 RR3254 pKa = 11.84 LRR3256 pKa = 11.84 RR3257 pKa = 11.84 PAAAPRR3263 pKa = 11.84 RR3264 pKa = 11.84 RR3265 pKa = 11.84 RR3266 pKa = 11.84 PRR3268 pKa = 11.84 RR3269 pKa = 11.84 LRR3271 pKa = 11.84 RR3272 pKa = 11.84 PAAAPRR3278 pKa = 11.84 RR3279 pKa = 11.84 RR3280 pKa = 11.84 RR3281 pKa = 11.84 RR3282 pKa = 11.84 RR3283 pKa = 11.84 RR3284 pKa = 11.84 LRR3286 pKa = 11.84 RR3287 pKa = 11.84 PAAAPRR3293 pKa = 11.84 RR3294 pKa = 11.84 QRR3296 pKa = 11.84 RR3297 pKa = 11.84 RR3298 pKa = 11.84 RR3299 pKa = 11.84 LRR3301 pKa = 11.84 RR3302 pKa = 11.84 PAAAPRR3308 pKa = 11.84 RR3309 pKa = 11.84 RR3310 pKa = 11.84 RR3311 pKa = 11.84 PRR3313 pKa = 11.84 RR3314 pKa = 11.84 LRR3316 pKa = 11.84 RR3317 pKa = 11.84 PAAAPRR3323 pKa = 11.84 RR3324 pKa = 11.84 RR3325 pKa = 11.84 RR3326 pKa = 11.84 RR3327 pKa = 11.84 RR3328 pKa = 11.84 RR3329 pKa = 11.84 LRR3331 pKa = 11.84 RR3332 pKa = 11.84 PAAAPRR3338 pKa = 11.84 RR3339 pKa = 11.84 RR3340 pKa = 11.84 RR3341 pKa = 11.84 PRR3343 pKa = 11.84 RR3344 pKa = 11.84 LRR3346 pKa = 11.84 RR3347 pKa = 11.84 PAAAPRR3353 pKa = 11.84 RR3354 pKa = 11.84 QRR3356 pKa = 11.84 PRR3358 pKa = 11.84 RR3359 pKa = 11.84 LRR3361 pKa = 11.84 RR3362 pKa = 11.84 PAAAPRR3368 pKa = 11.84 RR3369 pKa = 11.84 RR3370 pKa = 11.84 RR3371 pKa = 11.84 PRR3373 pKa = 11.84 RR3374 pKa = 11.84 LRR3376 pKa = 11.84 RR3377 pKa = 11.84 PAAAPRR3383 pKa = 11.84 HH3384 pKa = 4.72 LRR3386 pKa = 11.84 RR3387 pKa = 11.84 RR3388 pKa = 11.84 RR3389 pKa = 11.84 LRR3391 pKa = 11.84 RR3392 pKa = 11.84 PAAAPRR3398 pKa = 11.84 RR3399 pKa = 11.84 QRR3401 pKa = 11.84 PRR3403 pKa = 11.84 RR3404 pKa = 11.84 LHH3406 pKa = 6.4 RR3407 pKa = 11.84 PAAAPRR3413 pKa = 11.84 RR3414 pKa = 11.84 RR3415 pKa = 11.84 RR3416 pKa = 11.84 PRR3418 pKa = 11.84 RR3419 pKa = 11.84 LRR3421 pKa = 11.84 RR3422 pKa = 11.84 PAAAPRR3428 pKa = 11.84 RR3429 pKa = 11.84 RR3430 pKa = 11.84 RR3431 pKa = 11.84 PRR3433 pKa = 11.84 RR3434 pKa = 11.84 LRR3436 pKa = 11.84 RR3437 pKa = 11.84 PAAAPRR3443 pKa = 11.84 RR3444 pKa = 11.84 QRR3446 pKa = 11.84 PRR3448 pKa = 11.84 RR3449 pKa = 11.84 LRR3451 pKa = 11.84 RR3452 pKa = 11.84 PAAAPRR3458 pKa = 11.84 RR3459 pKa = 11.84 RR3460 pKa = 11.84 RR3461 pKa = 11.84 PRR3463 pKa = 11.84 RR3464 pKa = 11.84 LRR3466 pKa = 11.84 RR3467 pKa = 11.84 PAAAPRR3473 pKa = 11.84 RR3474 pKa = 11.84 QRR3476 pKa = 11.84 PRR3478 pKa = 11.84 RR3479 pKa = 11.84 LHH3481 pKa = 6.4 RR3482 pKa = 11.84 PAAAPRR3488 pKa = 11.84 RR3489 pKa = 11.84 QRR3491 pKa = 11.84 PRR3493 pKa = 11.84 RR3494 pKa = 11.84 LHH3496 pKa = 6.4 RR3497 pKa = 11.84 PAAAPRR3503 pKa = 11.84 RR3504 pKa = 11.84 RR3505 pKa = 11.84 RR3506 pKa = 11.84 PRR3508 pKa = 11.84 RR3509 pKa = 11.84 LRR3511 pKa = 11.84 RR3512 pKa = 11.84 PAAAPRR3518 pKa = 11.84 RR3519 pKa = 11.84 RR3520 pKa = 11.84 RR3521 pKa = 11.84 RR3522 pKa = 11.84 RR3523 pKa = 11.84 RR3524 pKa = 11.84 LRR3526 pKa = 11.84 RR3527 pKa = 11.84 PAAAPRR3533 pKa = 11.84 HH3534 pKa = 4.72 LRR3536 pKa = 11.84 RR3537 pKa = 11.84 RR3538 pKa = 11.84 RR3539 pKa = 11.84 LRR3541 pKa = 11.84 RR3542 pKa = 11.84 PAAAPRR3548 pKa = 11.84 RR3549 pKa = 11.84 RR3550 pKa = 11.84 RR3551 pKa = 11.84 RR3552 pKa = 11.84 RR3553 pKa = 11.84 RR3554 pKa = 11.84 LRR3556 pKa = 11.84 RR3557 pKa = 11.84 PAAAPRR3563 pKa = 11.84 HH3564 pKa = 4.96 RR3565 pKa = 11.84 RR3566 pKa = 11.84 RR3567 pKa = 11.84 RR3568 pKa = 11.84 RR3569 pKa = 11.84 LRR3571 pKa = 11.84 RR3572 pKa = 11.84 PAAAPRR3578 pKa = 11.84 RR3579 pKa = 11.84 RR3580 pKa = 11.84 RR3581 pKa = 11.84 RR3582 pKa = 11.84 RR3583 pKa = 11.84 RR3584 pKa = 11.84 LRR3586 pKa = 11.84 RR3587 pKa = 11.84 PAAAPRR3593 pKa = 11.84 RR3594 pKa = 11.84 RR3595 pKa = 11.84 RR3596 pKa = 11.84 PRR3598 pKa = 11.84 RR3599 pKa = 11.84 LRR3601 pKa = 11.84 RR3602 pKa = 11.84 PAAAPRR3608 pKa = 11.84 RR3609 pKa = 11.84 RR3610 pKa = 11.84 RR3611 pKa = 11.84 RR3612 pKa = 11.84 RR3613 pKa = 11.84 RR3614 pKa = 11.84 LRR3616 pKa = 11.84 RR3617 pKa = 11.84 PAAAPRR3623 pKa = 11.84 RR3624 pKa = 11.84 RR3625 pKa = 11.84 RR3626 pKa = 11.84 PRR3628 pKa = 11.84 RR3629 pKa = 11.84 LRR3631 pKa = 11.84 RR3632 pKa = 11.84 PAAAPRR3638 pKa = 11.84 RR3639 pKa = 11.84 RR3640 pKa = 11.84 RR3641 pKa = 11.84 RR3642 pKa = 11.84 RR3643 pKa = 11.84 RR3644 pKa = 11.84 LRR3646 pKa = 11.84 RR3647 pKa = 11.84 PAAAPRR3653 pKa = 11.84 RR3654 pKa = 11.84 RR3655 pKa = 11.84 RR3656 pKa = 11.84 RR3657 pKa = 11.84 RR3658 pKa = 11.84 RR3659 pKa = 11.84 LRR3661 pKa = 11.84 RR3662 pKa = 11.84 PAAAPRR3668 pKa = 11.84 RR3669 pKa = 11.84 QRR3671 pKa = 11.84 RR3672 pKa = 11.84 RR3673 pKa = 11.84 RR3674 pKa = 11.84 LRR3676 pKa = 11.84 RR3677 pKa = 11.84 PAAALRR3683 pKa = 11.84 RR3684 pKa = 11.84 RR3685 pKa = 11.84 RR3686 pKa = 11.84 RR3687 pKa = 11.84 RR3688 pKa = 11.84 RR3689 pKa = 11.84 LRR3691 pKa = 11.84 RR3692 pKa = 11.84 PAAAPRR3698 pKa = 11.84 RR3699 pKa = 11.84 QRR3701 pKa = 11.84 PRR3703 pKa = 11.84 RR3704 pKa = 11.84 LRR3706 pKa = 11.84 RR3707 pKa = 11.84 PAAAPRR3713 pKa = 11.84 RR3714 pKa = 11.84 RR3715 pKa = 11.84 RR3716 pKa = 11.84 RR3717 pKa = 11.84 RR3718 pKa = 11.84 RR3719 pKa = 11.84 LRR3721 pKa = 11.84 RR3722 pKa = 11.84 PAAAPRR3728 pKa = 11.84 RR3729 pKa = 11.84 RR3730 pKa = 11.84 RR3731 pKa = 11.84 RR3732 pKa = 11.84 RR3733 pKa = 11.84 RR3734 pKa = 11.84 LRR3736 pKa = 11.84 RR3737 pKa = 11.84 PAAAPRR3743 pKa = 11.84 RR3744 pKa = 11.84 RR3745 pKa = 11.84 RR3746 pKa = 11.84 RR3747 pKa = 11.84 RR3748 pKa = 11.84 RR3749 pKa = 11.84 LRR3751 pKa = 11.84 RR3752 pKa = 11.84 PAAAPRR3758 pKa = 11.84 RR3759 pKa = 11.84 RR3760 pKa = 11.84 RR3761 pKa = 11.84 PRR3763 pKa = 11.84 RR3764 pKa = 11.84 LRR3766 pKa = 11.84 RR3767 pKa = 11.84 PAAAPRR3773 pKa = 11.84 RR3774 pKa = 11.84 RR3775 pKa = 11.84 RR3776 pKa = 11.84 RR3777 pKa = 11.84 RR3778 pKa = 11.84 RR3779 pKa = 11.84 LRR3781 pKa = 11.84 RR3782 pKa = 11.84 PAAALRR3788 pKa = 11.84 RR3789 pKa = 11.84 RR3790 pKa = 11.84 RR3791 pKa = 11.84 PRR3793 pKa = 11.84 RR3794 pKa = 11.84 LRR3796 pKa = 11.84 RR3797 pKa = 11.84 PAAAPRR3803 pKa = 11.84 RR3804 pKa = 11.84 PAAAPRR3810 pKa = 11.84 HH3811 pKa = 4.96 RR3812 pKa = 11.84 RR3813 pKa = 11.84 RR3814 pKa = 11.84 RR3815 pKa = 11.84 RR3816 pKa = 11.84 LRR3818 pKa = 11.84 RR3819 pKa = 11.84 PAAAPRR3825 pKa = 11.84 RR3826 pKa = 11.84 RR3827 pKa = 11.84 RR3828 pKa = 11.84 PRR3830 pKa = 11.84 RR3831 pKa = 11.84 LRR3833 pKa = 11.84 RR3834 pKa = 11.84 PAAALRR3840 pKa = 11.84 RR3841 pKa = 11.84 RR3842 pKa = 11.84 RR3843 pKa = 11.84 PRR3845 pKa = 11.84 RR3846 pKa = 11.84 LRR3848 pKa = 11.84 RR3849 pKa = 11.84 PAAAPRR3855 pKa = 11.84 RR3856 pKa = 11.84 RR3857 pKa = 11.84 RR3858 pKa = 11.84 PRR3860 pKa = 11.84 RR3861 pKa = 11.84 LRR3863 pKa = 11.84 RR3864 pKa = 11.84 PAAALRR3870 pKa = 11.84 RR3871 pKa = 11.84 RR3872 pKa = 11.84 RR3873 pKa = 11.84 RR3874 pKa = 11.84 RR3875 pKa = 11.84 RR3876 pKa = 11.84 LRR3878 pKa = 11.84 RR3879 pKa = 11.84 PAAAPRR3885 pKa = 11.84 RR3886 pKa = 11.84 PAAAPRR3892 pKa = 11.84 RR3893 pKa = 11.84 RR3894 pKa = 11.84 RR3895 pKa = 11.84 RR3896 pKa = 11.84 RR3897 pKa = 11.84 RR3898 pKa = 11.84 LHH3900 pKa = 6.46 RR3901 pKa = 11.84 PAAAPRR3907 pKa = 11.84 RR3908 pKa = 11.84 RR3909 pKa = 11.84 RR3910 pKa = 11.84 PRR3912 pKa = 11.84 RR3913 pKa = 11.84 LHH3915 pKa = 6.45 RR3916 pKa = 11.84 PAAAPRR3922 pKa = 11.84 RR3923 pKa = 11.84 RR3924 pKa = 11.84 RR3925 pKa = 11.84 PRR3927 pKa = 11.84 RR3928 pKa = 11.84 LHH3930 pKa = 6.35 RR3931 pKa = 11.84 PAAALRR3937 pKa = 11.84 RR3938 pKa = 11.84 RR3939 pKa = 11.84 RR3940 pKa = 11.84 RR3941 pKa = 11.84 RR3942 pKa = 11.84 RR3943 pKa = 11.84 LHH3945 pKa = 6.46 RR3946 pKa = 11.84 PAAAPRR3952 pKa = 11.84 RR3953 pKa = 11.84 RR3954 pKa = 11.84 RR3955 pKa = 11.84 RR3956 pKa = 11.84 RR3957 pKa = 11.84 RR3958 pKa = 11.84 LRR3960 pKa = 11.84 RR3961 pKa = 11.84 PAAAPRR3967 pKa = 11.84 RR3968 pKa = 11.84 RR3969 pKa = 11.84 RR3970 pKa = 11.84 RR3971 pKa = 11.84 RR3972 pKa = 11.84 RR3973 pKa = 11.84 LRR3975 pKa = 11.84 RR3976 pKa = 11.84 PAAAPRR3982 pKa = 11.84 RR3983 pKa = 11.84 RR3984 pKa = 11.84 RR3985 pKa = 11.84 PRR3987 pKa = 11.84 RR3988 pKa = 11.84 LRR3990 pKa = 11.84 RR3991 pKa = 11.84 PAAAPRR3997 pKa = 11.84 RR3998 pKa = 11.84 RR3999 pKa = 11.84 RR4000 pKa = 11.84 RR4001 pKa = 11.84 RR4002 pKa = 11.84 RR4003 pKa = 11.84 LRR4005 pKa = 11.84 RR4006 pKa = 11.84 PAAAPRR4012 pKa = 11.84 RR4013 pKa = 11.84 RR4014 pKa = 11.84 RR4015 pKa = 11.84 RR4016 pKa = 11.84 RR4017 pKa = 11.84 RR4018 pKa = 11.84 LRR4020 pKa = 11.84 RR4021 pKa = 11.84 PAAAPRR4027 pKa = 11.84 RR4028 pKa = 11.84 RR4029 pKa = 11.84 RR4030 pKa = 11.84 PRR4032 pKa = 11.84 RR4033 pKa = 11.84 LRR4035 pKa = 11.84 RR4036 pKa = 11.84 PAAAPRR4042 pKa = 11.84 RR4043 pKa = 11.84 RR4044 pKa = 11.84 RR4045 pKa = 11.84 PRR4047 pKa = 11.84 RR4048 pKa = 11.84 LRR4050 pKa = 11.84 RR4051 pKa = 11.84 PAAAPRR4057 pKa = 11.84 RR4058 pKa = 11.84 RR4059 pKa = 11.84 RR4060 pKa = 11.84 PRR4062 pKa = 11.84 RR4063 pKa = 11.84 LRR4065 pKa = 11.84 RR4066 pKa = 11.84 PAAAPRR4072 pKa = 11.84 RR4073 pKa = 11.84 RR4074 pKa = 11.84 RR4075 pKa = 11.84 PRR4077 pKa = 11.84 RR4078 pKa = 11.84 LRR4080 pKa = 11.84 RR4081 pKa = 11.84 PAAAPRR4087 pKa = 11.84 RR4088 pKa = 11.84 RR4089 pKa = 11.84 RR4090 pKa = 11.84 PRR4092 pKa = 11.84 RR4093 pKa = 11.84 LRR4095 pKa = 11.84 RR4096 pKa = 11.84 PAAAPRR4102 pKa = 11.84 RR4103 pKa = 11.84 RR4104 pKa = 11.84 RR4105 pKa = 11.84 PRR4107 pKa = 11.84 RR4108 pKa = 11.84 LRR4110 pKa = 11.84 RR4111 pKa = 11.84 PAAAPRR4117 pKa = 11.84 RR4118 pKa = 11.84 RR4119 pKa = 11.84 RR4120 pKa = 11.84 PRR4122 pKa = 11.84 RR4123 pKa = 11.84 LHH4125 pKa = 6.45 RR4126 pKa = 11.84 PAAAPRR4132 pKa = 11.84 RR4133 pKa = 11.84 RR4134 pKa = 11.84 RR4135 pKa = 11.84 PRR4137 pKa = 11.84 RR4138 pKa = 11.84 LHH4140 pKa = 6.45 RR4141 pKa = 11.84 PAAAPRR4147 pKa = 11.84 RR4148 pKa = 11.84 RR4149 pKa = 11.84 RR4150 pKa = 11.84 RR4151 pKa = 11.84 RR4152 pKa = 11.84 RR4153 pKa = 11.84 LRR4155 pKa = 11.84 RR4156 pKa = 11.84 PAAAPRR4162 pKa = 11.84 RR4163 pKa = 11.84 QRR4165 pKa = 11.84 PRR4167 pKa = 11.84 RR4168 pKa = 11.84 LRR4170 pKa = 11.84 RR4171 pKa = 11.84 PAAAPRR4177 pKa = 11.84 RR4178 pKa = 11.84 QRR4180 pKa = 11.84 PRR4182 pKa = 11.84 RR4183 pKa = 11.84 LHH4185 pKa = 6.4 RR4186 pKa = 11.84 PAAAPRR4192 pKa = 11.84 RR4193 pKa = 11.84 QRR4195 pKa = 11.84 PRR4197 pKa = 11.84 RR4198 pKa = 11.84 LRR4200 pKa = 11.84 RR4201 pKa = 11.84 PAAAPRR4207 pKa = 11.84 RR4208 pKa = 11.84 RR4209 pKa = 11.84 RR4210 pKa = 11.84 RR4211 pKa = 11.84 RR4212 pKa = 11.84 RR4213 pKa = 11.84 LHH4215 pKa = 6.46 RR4216 pKa = 11.84 PAAAPRR4222 pKa = 11.84 RR4223 pKa = 11.84 QRR4225 pKa = 11.84 PRR4227 pKa = 11.84 RR4228 pKa = 11.84 LRR4230 pKa = 11.84 RR4231 pKa = 11.84 PEE4233 pKa = 3.7 AAPRR4237 pKa = 11.84 RR4238 pKa = 4.1
Molecular weight: 474.41 kDa
Isoelectric point according different methods:
IPC2.protein.svr19 9.527
IPC2_protein 11.359
IPC_protein 12.939
Toseland 13.1
ProMoST 13.598
Dawson 13.1
Bjellqvist 13.1
Wikipedia 13.583
Rodwell 12.603
Grimsley 13.144
Solomon 13.598
Lehninger 13.495
Nozaki 13.1
DTASelect 13.1
Thurlkill 13.1
EMBOSS 13.598
Sillero 13.1
Patrickios 12.31
IPC_peptide 13.598
IPC2_peptide 12.588
IPC2.peptide.svr19 9.275
Peptides (in silico digests for buttom-up proteomics)
Below you can find
in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.
Try ESI
ChTry ESI
ArgC ESI
LysN ESI
TryLysC ESI
Try MALDI
ChTry MALDI
ArgC MALDI
LysN MALDI
TryLysC MALDI
Try LTQ
ChTry LTQ
ArgC LTQ
LysN LTQ
TryLysC LTQ
Try MSlow
ChTry MSlow
ArgC MSlow
LysN MSlow
TryLysC MSlow
Try MShigh
ChTry MShigh
ArgC MShigh
LysN MShigh
TryLysC MShigh
General Statistics
Number of major isoforms
Number of additional isoforms
Number of all proteins
Number of amino acids
Min. Seq. Length
Max. Seq. Length
Avg. Seq. Length
Avg. Mol. Weight
8045
0
8045
5116451
34
7009
636.0
69.1
Amino acid frequency
Ala
Cys
Asp
Glu
Phe
Gly
His
Ile
Lys
Leu
12.131 ± 0.039
1.874 ± 0.012
4.867 ± 0.019
5.995 ± 0.035
2.946 ± 0.017
6.487 ± 0.029
2.693 ± 0.012
2.974 ± 0.02
3.329 ± 0.026
9.186 ± 0.03
Met
Asn
Gln
Pro
Arg
Ser
Thr
Val
Trp
Tyr
2.252 ± 0.012
2.617 ± 0.015
5.823 ± 0.03
4.141 ± 0.026
7.269 ± 0.03
8.847 ± 0.059
5.965 ± 0.021
7.143 ± 0.038
1.07 ± 0.008
2.39 ± 0.014
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level
Most of the basic statistics you can see at this page can be downloaded from this CSV file
For dipeptide frequency statistics click here