Amino acid dipepetide frequency for Lake Sarah-associated circular virus-11

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.17AlaAla: 8.17 ± 0.133
1.634AlaCys: 1.634 ± 0.777
3.268AlaAsp: 3.268 ± 1.555
4.902AlaGlu: 4.902 ± 1.421
4.902AlaPhe: 4.902 ± 1.421
3.268AlaGly: 3.268 ± 0.322
1.634AlaHis: 1.634 ± 0.777
6.536AlaIle: 6.536 ± 0.644
8.17AlaLys: 8.17 ± 1.743
4.902AlaLeu: 4.902 ± 0.455
1.634AlaMet: 1.634 ± 1.099
3.268AlaAsn: 3.268 ± 0.322
1.634AlaPro: 1.634 ± 0.777
1.634AlaGln: 1.634 ± 0.777
1.634AlaArg: 1.634 ± 1.099
6.536AlaSer: 6.536 ± 0.644
4.902AlaThr: 4.902 ± 2.332
1.634AlaVal: 1.634 ± 0.777
0.0AlaTrp: 0.0 ± 0.0
3.268AlaTyr: 3.268 ± 0.322
0.0AlaXaa: 0.0 ± 0.0
Cys
1.634CysAla: 1.634 ± 0.777
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.634CysGlu: 1.634 ± 0.777
1.634CysPhe: 1.634 ± 0.777
1.634CysGly: 1.634 ± 0.777
1.634CysHis: 1.634 ± 0.777
0.0CysIle: 0.0 ± 0.0
1.634CysLys: 1.634 ± 0.777
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
3.268CysSer: 3.268 ± 1.555
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
3.268CysTyr: 3.268 ± 0.322
0.0CysXaa: 0.0 ± 0.0
Asp
3.268AspAla: 3.268 ± 0.322
0.0AspCys: 0.0 ± 0.0
1.634AspAsp: 1.634 ± 1.099
4.902AspGlu: 4.902 ± 0.455
3.268AspPhe: 3.268 ± 0.322
1.634AspGly: 1.634 ± 1.099
3.268AspHis: 3.268 ± 0.322
3.268AspIle: 3.268 ± 0.322
1.634AspLys: 1.634 ± 0.777
3.268AspLeu: 3.268 ± 0.322
0.0AspMet: 0.0 ± 0.0
4.902AspAsn: 4.902 ± 1.421
0.0AspPro: 0.0 ± 0.0
0.0AspGln: 0.0 ± 0.0
1.634AspArg: 1.634 ± 0.777
4.902AspSer: 4.902 ± 3.298
3.268AspThr: 3.268 ± 0.322
0.0AspVal: 0.0 ± 0.0
0.0AspTrp: 0.0 ± 0.0
3.268AspTyr: 3.268 ± 1.555
0.0AspXaa: 0.0 ± 0.0
Glu
4.902GluAla: 4.902 ± 1.421
1.634GluCys: 1.634 ± 0.777
3.268GluAsp: 3.268 ± 1.555
6.536GluGlu: 6.536 ± 1.233
3.268GluPhe: 3.268 ± 1.555
4.902GluGly: 4.902 ± 1.421
1.634GluHis: 1.634 ± 0.777
1.634GluIle: 1.634 ± 0.777
4.902GluLys: 4.902 ± 2.332
3.268GluLeu: 3.268 ± 0.322
0.0GluMet: 0.0 ± 0.0
1.634GluAsn: 1.634 ± 0.777
4.902GluPro: 4.902 ± 2.332
1.634GluGln: 1.634 ± 0.777
6.536GluArg: 6.536 ± 3.109
6.536GluSer: 6.536 ± 3.109
1.634GluThr: 1.634 ± 0.777
1.634GluVal: 1.634 ± 0.777
1.634GluTrp: 1.634 ± 1.099
3.268GluTyr: 3.268 ± 1.555
0.0GluXaa: 0.0 ± 0.0
Phe
6.536PheAla: 6.536 ± 2.52
1.634PheCys: 1.634 ± 0.777
1.634PheAsp: 1.634 ± 0.777
6.536PheGlu: 6.536 ± 3.109
0.0PhePhe: 0.0 ± 0.0
4.902PheGly: 4.902 ± 1.421
0.0PheHis: 0.0 ± 0.0
1.634PheIle: 1.634 ± 0.777
0.0PheLys: 0.0 ± 0.0
6.536PheLeu: 6.536 ± 1.233
0.0PheMet: 0.0 ± 0.0
4.902PheAsn: 4.902 ± 0.455
1.634PhePro: 1.634 ± 0.777
0.0PheGln: 0.0 ± 0.0
3.268PheArg: 3.268 ± 0.322
3.268PheSer: 3.268 ± 0.322
6.536PheThr: 6.536 ± 1.233
4.902PheVal: 4.902 ± 1.421
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
1.634GlyAla: 1.634 ± 0.777
1.634GlyCys: 1.634 ± 0.777
3.268GlyAsp: 3.268 ± 2.198
4.902GlyGlu: 4.902 ± 2.332
4.902GlyPhe: 4.902 ± 1.421
14.706GlyGly: 14.706 ± 2.387
0.0GlyHis: 0.0 ± 0.0
0.0GlyIle: 0.0 ± 0.0
9.804GlyLys: 9.804 ± 0.966
3.268GlyLeu: 3.268 ± 0.322
1.634GlyMet: 1.634 ± 0.777
6.536GlyAsn: 6.536 ± 2.52
0.0GlyPro: 0.0 ± 0.0
0.0GlyGln: 0.0 ± 0.0
8.17GlyArg: 8.17 ± 3.62
1.634GlySer: 1.634 ± 0.777
4.902GlyThr: 4.902 ± 2.332
3.268GlyVal: 3.268 ± 2.198
1.634GlyTrp: 1.634 ± 1.099
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
1.634HisAsp: 1.634 ± 1.099
0.0HisGlu: 0.0 ± 0.0
1.634HisPhe: 1.634 ± 0.777
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
4.902HisIle: 4.902 ± 0.455
0.0HisLys: 0.0 ± 0.0
4.902HisLeu: 4.902 ± 0.455
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.634HisPro: 1.634 ± 0.777
0.0HisGln: 0.0 ± 0.0
1.634HisArg: 1.634 ± 1.099
1.634HisSer: 1.634 ± 0.777
0.0HisThr: 0.0 ± 0.0
1.634HisVal: 1.634 ± 0.777
1.634HisTrp: 1.634 ± 0.777
1.634HisTyr: 1.634 ± 0.777
0.0HisXaa: 0.0 ± 0.0
Ile
3.268IleAla: 3.268 ± 0.322
1.634IleCys: 1.634 ± 0.777
1.634IleAsp: 1.634 ± 1.099
3.268IleGlu: 3.268 ± 0.322
4.902IlePhe: 4.902 ± 2.332
1.634IleGly: 1.634 ± 0.777
1.634IleHis: 1.634 ± 0.777
3.268IleIle: 3.268 ± 1.555
6.536IleLys: 6.536 ± 1.233
0.0IleLeu: 0.0 ± 0.0
3.268IleMet: 3.268 ± 2.198
6.536IleAsn: 6.536 ± 1.233
1.634IlePro: 1.634 ± 0.777
1.634IleGln: 1.634 ± 0.777
1.634IleArg: 1.634 ± 0.777
3.268IleSer: 3.268 ± 0.322
3.268IleThr: 3.268 ± 0.322
1.634IleVal: 1.634 ± 1.099
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
3.268LysAla: 3.268 ± 0.322
0.0LysCys: 0.0 ± 0.0
1.634LysAsp: 1.634 ± 1.099
4.902LysGlu: 4.902 ± 2.332
3.268LysPhe: 3.268 ± 0.322
6.536LysGly: 6.536 ± 0.644
0.0LysHis: 0.0 ± 0.0
3.268LysIle: 3.268 ± 2.198
3.268LysLys: 3.268 ± 0.322
1.634LysLeu: 1.634 ± 0.777
1.634LysMet: 1.634 ± 0.777
4.902LysAsn: 4.902 ± 0.455
1.634LysPro: 1.634 ± 1.099
3.268LysGln: 3.268 ± 0.322
8.17LysArg: 8.17 ± 3.62
8.17LysSer: 8.17 ± 0.133
6.536LysThr: 6.536 ± 0.644
9.804LysVal: 9.804 ± 0.966
0.0LysTrp: 0.0 ± 0.0
6.536LysTyr: 6.536 ± 1.233
0.0LysXaa: 0.0 ± 0.0
Leu
8.17LeuAla: 8.17 ± 0.133
0.0LeuCys: 0.0 ± 0.0
1.634LeuAsp: 1.634 ± 0.777
3.268LeuGlu: 3.268 ± 1.555
3.268LeuPhe: 3.268 ± 0.322
1.634LeuGly: 1.634 ± 1.099
0.0LeuHis: 0.0 ± 0.0
3.268LeuIle: 3.268 ± 0.322
9.804LeuLys: 9.804 ± 0.966
4.902LeuLeu: 4.902 ± 2.332
1.634LeuMet: 1.634 ± 0.874
3.268LeuAsn: 3.268 ± 0.322
1.634LeuPro: 1.634 ± 0.777
4.902LeuGln: 4.902 ± 0.455
1.634LeuArg: 1.634 ± 0.777
4.902LeuSer: 4.902 ± 2.332
4.902LeuThr: 4.902 ± 0.455
4.902LeuVal: 4.902 ± 0.455
0.0LeuTrp: 0.0 ± 0.0
1.634LeuTyr: 1.634 ± 1.099
0.0LeuXaa: 0.0 ± 0.0
Met
1.634MetAla: 1.634 ± 0.777
0.0MetCys: 0.0 ± 0.0
1.634MetAsp: 1.634 ± 1.099
1.634MetGlu: 1.634 ± 1.099
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.634MetLys: 1.634 ± 1.099
1.634MetLeu: 1.634 ± 1.099
1.634MetMet: 1.634 ± 1.099
0.0MetAsn: 0.0 ± 0.0
1.634MetPro: 1.634 ± 1.099
1.634MetGln: 1.634 ± 1.099
1.634MetArg: 1.634 ± 0.777
3.268MetSer: 3.268 ± 1.555
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
1.634MetTrp: 1.634 ± 1.099
1.634MetTyr: 1.634 ± 1.099
0.0MetXaa: 0.0 ± 0.0
Asn
8.17AsnAla: 8.17 ± 1.743
1.634AsnCys: 1.634 ± 0.777
4.902AsnAsp: 4.902 ± 1.421
1.634AsnGlu: 1.634 ± 0.777
0.0AsnPhe: 0.0 ± 0.0
4.902AsnGly: 4.902 ± 0.455
0.0AsnHis: 0.0 ± 0.0
0.0AsnIle: 0.0 ± 0.0
1.634AsnLys: 1.634 ± 1.099
4.902AsnLeu: 4.902 ± 0.455
1.634AsnMet: 1.634 ± 1.099
6.536AsnAsn: 6.536 ± 2.52
0.0AsnPro: 0.0 ± 0.0
1.634AsnGln: 1.634 ± 1.099
1.634AsnArg: 1.634 ± 0.777
4.902AsnSer: 4.902 ± 1.421
8.17AsnThr: 8.17 ± 3.62
0.0AsnVal: 0.0 ± 0.0
1.634AsnTrp: 1.634 ± 0.777
1.634AsnTyr: 1.634 ± 0.777
0.0AsnXaa: 0.0 ± 0.0
Pro
0.0ProAla: 0.0 ± 0.0
0.0ProCys: 0.0 ± 0.0
3.268ProAsp: 3.268 ± 0.322
0.0ProGlu: 0.0 ± 0.0
3.268ProPhe: 3.268 ± 1.555
4.902ProGly: 4.902 ± 1.421
3.268ProHis: 3.268 ± 1.555
1.634ProIle: 1.634 ± 0.777
1.634ProLys: 1.634 ± 1.099
1.634ProLeu: 1.634 ± 0.777
0.0ProMet: 0.0 ± 0.0
0.0ProAsn: 0.0 ± 0.0
1.634ProPro: 1.634 ± 0.777
0.0ProGln: 0.0 ± 0.0
3.268ProArg: 3.268 ± 1.555
0.0ProSer: 0.0 ± 0.0
1.634ProThr: 1.634 ± 0.777
4.902ProVal: 4.902 ± 2.332
0.0ProTrp: 0.0 ± 0.0
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
1.634GlnAla: 1.634 ± 0.777
1.634GlnCys: 1.634 ± 1.099
0.0GlnAsp: 0.0 ± 0.0
1.634GlnGlu: 1.634 ± 0.777
3.268GlnPhe: 3.268 ± 2.198
1.634GlnGly: 1.634 ± 0.777
0.0GlnHis: 0.0 ± 0.0
3.268GlnIle: 3.268 ± 0.322
0.0GlnLys: 0.0 ± 0.0
3.268GlnLeu: 3.268 ± 0.322
0.0GlnMet: 0.0 ± 0.0
1.634GlnAsn: 1.634 ± 1.099
1.634GlnPro: 1.634 ± 1.099
6.536GlnGln: 6.536 ± 0.644
1.634GlnArg: 1.634 ± 0.777
1.634GlnSer: 1.634 ± 0.777
1.634GlnThr: 1.634 ± 0.777
1.634GlnVal: 1.634 ± 0.777
0.0GlnTrp: 0.0 ± 0.0
1.634GlnTyr: 1.634 ± 1.099
0.0GlnXaa: 0.0 ± 0.0
Arg
3.268ArgAla: 3.268 ± 1.555
0.0ArgCys: 0.0 ± 0.0
1.634ArgAsp: 1.634 ± 0.777
1.634ArgGlu: 1.634 ± 0.777
0.0ArgPhe: 0.0 ± 0.0
9.804ArgGly: 9.804 ± 0.966
3.268ArgHis: 3.268 ± 0.322
4.902ArgIle: 4.902 ± 0.455
4.902ArgLys: 4.902 ± 3.298
6.536ArgLeu: 6.536 ± 1.233
0.0ArgMet: 0.0 ± 0.0
0.0ArgAsn: 0.0 ± 0.0
1.634ArgPro: 1.634 ± 0.777
0.0ArgGln: 0.0 ± 0.0
13.072ArgArg: 13.072 ± 6.917
1.634ArgSer: 1.634 ± 0.777
4.902ArgThr: 4.902 ± 0.455
4.902ArgVal: 4.902 ± 3.298
3.268ArgTrp: 3.268 ± 1.555
1.634ArgTyr: 1.634 ± 1.099
0.0ArgXaa: 0.0 ± 0.0
Ser
3.268SerAla: 3.268 ± 1.555
1.634SerCys: 1.634 ± 0.777
1.634SerAsp: 1.634 ± 0.777
6.536SerGlu: 6.536 ± 3.109
6.536SerPhe: 6.536 ± 0.644
3.268SerGly: 3.268 ± 0.322
1.634SerHis: 1.634 ± 1.099
3.268SerIle: 3.268 ± 0.322
8.17SerLys: 8.17 ± 2.01
0.0SerLeu: 0.0 ± 0.0
0.0SerMet: 0.0 ± 0.0
4.902SerAsn: 4.902 ± 0.455
1.634SerPro: 1.634 ± 0.777
4.902SerGln: 4.902 ± 0.455
1.634SerArg: 1.634 ± 1.099
3.268SerSer: 3.268 ± 1.555
3.268SerThr: 3.268 ± 2.198
9.804SerVal: 9.804 ± 0.966
1.634SerTrp: 1.634 ± 0.777
1.634SerTyr: 1.634 ± 1.099
0.0SerXaa: 0.0 ± 0.0
Thr
4.902ThrAla: 4.902 ± 1.421
0.0ThrCys: 0.0 ± 0.0
1.634ThrAsp: 1.634 ± 0.777
4.902ThrGlu: 4.902 ± 2.332
3.268ThrPhe: 3.268 ± 1.555
4.902ThrGly: 4.902 ± 0.455
0.0ThrHis: 0.0 ± 0.0
4.902ThrIle: 4.902 ± 2.332
3.268ThrLys: 3.268 ± 1.555
4.902ThrLeu: 4.902 ± 1.421
1.634ThrMet: 1.634 ± 0.988
1.634ThrAsn: 1.634 ± 1.099
3.268ThrPro: 3.268 ± 1.555
1.634ThrGln: 1.634 ± 1.099
3.268ThrArg: 3.268 ± 1.555
4.902ThrSer: 4.902 ± 1.421
3.268ThrThr: 3.268 ± 0.322
3.268ThrVal: 3.268 ± 0.322
3.268ThrTrp: 3.268 ± 0.322
1.634ThrTyr: 1.634 ± 1.099
0.0ThrXaa: 0.0 ± 0.0
Val
3.268ValAla: 3.268 ± 0.322
1.634ValCys: 1.634 ± 0.777
3.268ValAsp: 3.268 ± 0.322
0.0ValGlu: 0.0 ± 0.0
3.268ValPhe: 3.268 ± 1.555
1.634ValGly: 1.634 ± 1.099
3.268ValHis: 3.268 ± 0.322
4.902ValIle: 4.902 ± 2.332
4.902ValLys: 4.902 ± 1.421
4.902ValLeu: 4.902 ± 0.455
0.0ValMet: 0.0 ± 0.0
4.902ValAsn: 4.902 ± 3.298
4.902ValPro: 4.902 ± 0.455
0.0ValGln: 0.0 ± 0.0
6.536ValArg: 6.536 ± 0.644
1.634ValSer: 1.634 ± 1.099
0.0ValThr: 0.0 ± 0.0
4.902ValVal: 4.902 ± 1.421
1.634ValTrp: 1.634 ± 0.777
3.268ValTyr: 3.268 ± 2.198
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
3.268TrpGlu: 3.268 ± 0.322
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
1.634TrpHis: 1.634 ± 0.777
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
1.634TrpLeu: 1.634 ± 1.099
3.268TrpMet: 3.268 ± 0.322
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
3.268TrpGln: 3.268 ± 0.322
0.0TrpArg: 0.0 ± 0.0
1.634TrpSer: 1.634 ± 0.777
3.268TrpThr: 3.268 ± 1.555
0.0TrpVal: 0.0 ± 0.0
1.634TrpTrp: 1.634 ± 1.099
1.634TrpTyr: 1.634 ± 0.777
0.0TrpXaa: 0.0 ± 0.0
Tyr
6.536TyrAla: 6.536 ± 1.233
1.634TyrCys: 1.634 ± 0.777
6.536TyrAsp: 6.536 ± 2.52
3.268TyrGlu: 3.268 ± 1.555
3.268TyrPhe: 3.268 ± 0.322
0.0TyrGly: 0.0 ± 0.0
0.0TyrHis: 0.0 ± 0.0
0.0TyrIle: 0.0 ± 0.0
6.536TyrLys: 6.536 ± 2.52
3.268TyrLeu: 3.268 ± 1.555
1.634TyrMet: 1.634 ± 1.099
0.0TyrAsn: 0.0 ± 0.0
0.0TyrPro: 0.0 ± 0.0
1.634TyrGln: 1.634 ± 1.099
0.0TyrArg: 0.0 ± 0.0
1.634TyrSer: 1.634 ± 1.099
0.0TyrThr: 0.0 ± 0.0
0.0TyrVal: 0.0 ± 0.0
1.634TyrTrp: 1.634 ± 0.777
1.634TyrTyr: 1.634 ± 1.099
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (613 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski