Pantherophis guttatus (Corn snake) (Elaphe guttata)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Sauropsida; Sauria;

Average proteome isoelectric point is 6.62

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 33951 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A6P9B308|A0A6P9B308_PANGU glycosaminoglycan xylosylkinase OS=Pantherophis guttatus OX=94885 GN=FAM20B PE=3 SV=1
FF1 pKa = 7.05MEE3 pKa = 5.82SEE5 pKa = 4.7LDD7 pKa = 3.68LNDD10 pKa = 4.95IIQEE14 pKa = 4.03MHH16 pKa = 6.28VVATMPDD23 pKa = 4.18LYY25 pKa = 11.11HH26 pKa = 7.42LLVEE30 pKa = 4.56LNAVHH35 pKa = 6.82SLLGLLGHH43 pKa = 7.44DD44 pKa = 3.8NTDD47 pKa = 2.85VAIAVVDD54 pKa = 4.4LLQEE58 pKa = 4.11LTDD61 pKa = 3.45IDD63 pKa = 4.07TLHH66 pKa = 6.67EE67 pKa = 4.39SEE69 pKa = 4.86EE70 pKa = 4.52GAGVLIDD77 pKa = 4.19SLVSSTWWHH86 pKa = 6.67LGLGWGSNPP95 pKa = 4.14

Molecular weight: 10.44 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A6P9CQI5|A0A6P9CQI5_PANGU Tyrosine-protein kinase OS=Pantherophis guttatus OX=94885 GN=YES1 PE=3 SV=1
MM1 pKa = 7.57SSHH4 pKa = 6.01KK5 pKa = 9.07TFKK8 pKa = 10.28IKK10 pKa = 10.6RR11 pKa = 11.84FLAKK15 pKa = 9.68KK16 pKa = 9.58QKK18 pKa = 8.69QNRR21 pKa = 11.84PIPQWIRR28 pKa = 11.84MKK30 pKa = 9.89TGNKK34 pKa = 8.61IRR36 pKa = 11.84YY37 pKa = 7.09NSKK40 pKa = 8.3RR41 pKa = 11.84RR42 pKa = 11.84HH43 pKa = 3.95WRR45 pKa = 11.84RR46 pKa = 11.84TKK48 pKa = 10.83LGLL51 pKa = 3.67

Molecular weight: 6.38 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

19712

14239

33951

23272350

31

34038

685.5

76.86

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.31 ± 0.01

2.128 ± 0.01

4.902 ± 0.009

7.44 ± 0.02

3.691 ± 0.01

5.89 ± 0.016

2.606 ± 0.006

5.001 ± 0.011

6.418 ± 0.017

9.65 ± 0.018

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.276 ± 0.005

4.182 ± 0.009

5.677 ± 0.019

4.943 ± 0.015

5.213 ± 0.01

8.688 ± 0.016

5.401 ± 0.009

5.723 ± 0.01

1.12 ± 0.004

2.741 ± 0.008
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski