Cynomolgus cytomegalovirus

Taxonomy: Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes; Herpesvirales; Herpesviridae; Betaherpesvirinae; Cytomegalovirus; unclassified Cytomegalovirus

Average proteome isoelectric point is 6.99

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 173 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A1L6Z020|A0A1L6Z020_9BETA Capsid scaffolding protein OS=Cynomolgus cytomegalovirus OX=1919083 PE=3 SV=1
MM1 pKa = 7.5RR2 pKa = 11.84WVAMRR7 pKa = 11.84WLLLIVATSAKK18 pKa = 10.29ASSTTAGNTSTPTASTITSTVTTASTTNMSTPSPASSPATTNTTTSSPSTKK69 pKa = 10.33SSTSSTNTTITTTGTASATTPKK91 pKa = 10.4SSTSVTSSPANSTSTSTKK109 pKa = 9.78PSTTNTSSPITTSSPASNTSTTTSSTSTVNGTNSTTEE146 pKa = 4.13TNTTSLPDD154 pKa = 3.27TTADD158 pKa = 3.45MNVTTTEE165 pKa = 4.5PYY167 pKa = 10.96NSTGYY172 pKa = 11.03EE173 pKa = 3.7NVTINITTPSPYY185 pKa = 10.0EE186 pKa = 3.61ALQIVDD192 pKa = 4.79LCNEE196 pKa = 4.43TISIVFKK203 pKa = 11.14DD204 pKa = 3.61PGEE207 pKa = 4.06EE208 pKa = 4.2DD209 pKa = 3.46EE210 pKa = 5.09SSEE213 pKa = 3.95TTEE216 pKa = 4.2YY217 pKa = 11.17SDD219 pKa = 4.21EE220 pKa = 4.3EE221 pKa = 4.3PVASSNEE228 pKa = 3.83DD229 pKa = 3.2DD230 pKa = 3.48STYY233 pKa = 10.3FPQSPGYY240 pKa = 7.88TLTYY244 pKa = 9.43DD245 pKa = 3.78TEE247 pKa = 4.17DD248 pKa = 3.27TIYY251 pKa = 10.65FQATCDD257 pKa = 4.08RR258 pKa = 11.84NDD260 pKa = 3.33TYY262 pKa = 11.56NITSCDD268 pKa = 3.68YY269 pKa = 10.21TNKK272 pKa = 10.2SVNSWSTVTSVSFFPPTLTPCHH294 pKa = 6.56KK295 pKa = 9.56PVAIIKK301 pKa = 9.88IGNDD305 pKa = 3.25SLVVSASATSNLVDD319 pKa = 5.76AIYY322 pKa = 10.99KK323 pKa = 10.49LLGLPDD329 pKa = 3.78VNSDD333 pKa = 4.72FINQLGRR340 pKa = 11.84YY341 pKa = 8.7HH342 pKa = 7.95PITLQGQIEE351 pKa = 4.19YY352 pKa = 9.97RR353 pKa = 11.84DD354 pKa = 3.61WYY356 pKa = 7.62TTEE359 pKa = 3.67

Molecular weight: 38.05 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A1L6YZS4|A0A1L6YZS4_9BETA Cy50.1 OS=Cynomolgus cytomegalovirus OX=1919083 PE=4 SV=1
MM1 pKa = 7.56ARR3 pKa = 11.84HH4 pKa = 6.08RR5 pKa = 11.84CHH7 pKa = 6.77KK8 pKa = 10.42CWLLWLTVILGSWIHH23 pKa = 6.3LLNALEE29 pKa = 4.01IVEE32 pKa = 4.73EE33 pKa = 4.2YY34 pKa = 11.11VEE36 pKa = 4.07EE37 pKa = 4.24QEE39 pKa = 6.3IIMQTTRR46 pKa = 11.84QMALRR51 pKa = 11.84LAAAPVRR58 pKa = 11.84GRR60 pKa = 11.84RR61 pKa = 11.84QEE63 pKa = 3.52IDD65 pKa = 3.18GRR67 pKa = 11.84PPSIPSWLDD76 pKa = 2.93VRR78 pKa = 11.84SPRR81 pKa = 11.84PPRR84 pKa = 11.84RR85 pKa = 11.84HH86 pKa = 6.97DD87 pKa = 3.55EE88 pKa = 3.7NTMQRR93 pKa = 11.84NIRR96 pKa = 11.84WQHH99 pKa = 4.73EE100 pKa = 4.06QMQVLMSLHH109 pKa = 6.6HH110 pKa = 6.7SRR112 pKa = 11.84MQARR116 pKa = 11.84GWNPDD121 pKa = 2.48QRR123 pKa = 11.84TPDD126 pKa = 3.43RR127 pKa = 11.84LPAHH131 pKa = 7.21FGRR134 pKa = 11.84SASGSRR140 pKa = 11.84PVPIQRR146 pKa = 11.84IGTSTRR152 pKa = 11.84PTPMAEE158 pKa = 3.98EE159 pKa = 4.33AEE161 pKa = 4.45EE162 pKa = 3.91PRR164 pKa = 11.84VTIVRR169 pKa = 11.84NRR171 pKa = 11.84RR172 pKa = 11.84PDD174 pKa = 3.19NSSPGPRR181 pKa = 11.84LPHH184 pKa = 6.25KK185 pKa = 10.17RR186 pKa = 11.84RR187 pKa = 11.84NAVTFTGSTDD197 pKa = 3.48SLDD200 pKa = 3.57LTRR203 pKa = 11.84LRR205 pKa = 11.84LSYY208 pKa = 10.28EE209 pKa = 3.53RR210 pKa = 11.84RR211 pKa = 11.84HH212 pKa = 5.58RR213 pKa = 11.84KK214 pKa = 9.0GYY216 pKa = 9.28YY217 pKa = 8.18RR218 pKa = 11.84WKK220 pKa = 9.73HH221 pKa = 5.0HH222 pKa = 5.87GKK224 pKa = 10.33RR225 pKa = 11.84SPTVKK230 pKa = 10.49AHH232 pKa = 6.7IPPPRR237 pKa = 11.84PTISDD242 pKa = 3.26PMEE245 pKa = 4.18FRR247 pKa = 11.84PAPSPVPQRR256 pKa = 11.84RR257 pKa = 11.84TLNEE261 pKa = 3.77RR262 pKa = 11.84FNDD265 pKa = 3.38LLRR268 pKa = 11.84RR269 pKa = 11.84HH270 pKa = 6.03SAHH273 pKa = 6.35EE274 pKa = 4.2NIRR277 pKa = 11.84HH278 pKa = 5.58KK279 pKa = 10.27WHH281 pKa = 6.26VRR283 pKa = 11.84PKK285 pKa = 10.59DD286 pKa = 3.72DD287 pKa = 4.98PVWIYY292 pKa = 11.51NDD294 pKa = 3.88GEE296 pKa = 4.66SEE298 pKa = 4.18VTSIGEE304 pKa = 4.09RR305 pKa = 11.84ASLLTRR311 pKa = 11.84TRR313 pKa = 11.84SWIQSHH319 pKa = 5.41MHH321 pKa = 5.83RR322 pKa = 11.84TYY324 pKa = 9.33TWRR327 pKa = 11.84LGSSGGGNEE336 pKa = 3.81PLVRR340 pKa = 11.84SLSTEE345 pKa = 3.65QPRR348 pKa = 11.84NNNANQSRR356 pKa = 11.84LHH358 pKa = 6.33SPSEE362 pKa = 4.21SVQVNLEE369 pKa = 3.94TGEE372 pKa = 4.39VVVTCHH378 pKa = 4.92NTGANEE384 pKa = 3.98QQHH387 pKa = 6.01VLTSNQLCSRR397 pKa = 11.84NSMEE401 pKa = 4.59VTDD404 pKa = 3.94ACDD407 pKa = 3.14RR408 pKa = 11.84EE409 pKa = 4.66TPRR412 pKa = 11.84RR413 pKa = 11.84ALLGSSIALWLSGMWMRR430 pKa = 11.84HH431 pKa = 3.95YY432 pKa = 10.52RR433 pKa = 11.84KK434 pKa = 10.15SSS436 pKa = 2.93

Molecular weight: 50.65 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

173

0

173

62217

53

2179

359.6

40.68

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.582 ± 0.144

2.676 ± 0.117

4.79 ± 0.139

5.235 ± 0.158

4.121 ± 0.117

4.568 ± 0.125

3.025 ± 0.116

5.174 ± 0.125

3.874 ± 0.143

9.88 ± 0.198

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.589 ± 0.089

4.285 ± 0.108

5.526 ± 0.204

3.893 ± 0.157

6.379 ± 0.153

7.948 ± 0.175

7.389 ± 0.271

6.961 ± 0.163

1.385 ± 0.077

3.721 ± 0.092
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski